ORF STATUS Function Best COG Functional category Pathways and functional systems
r_klactIV3028 good S KOG3790 Function unknown Uncharacterized conserved protein
Only best alignment is shown:
BLASTP 2.2.3 [May-13-2002]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= r_klactIV3028 1024590 1026200 537
(537 letters)
Database: KOG eukaryal database 04/03
60,738 sequences; 30,389,216 total letters
Searching..................................................done
Color Key for Alignment Scores: 
Score E
Sequences producing significant alignments: (bits) Value
YPL030w [S] KOG3790 Uncharacterized conserved protein 684 0.0
SPCC663.10 [S] KOG3790 Uncharacterized conserved protein 301 2e-81
7299200 [S] KOG3790 Uncharacterized conserved protein 136 9e-32
Hs22044059 [S] KOG3790 Uncharacterized conserved protein 125 1e-28
CE04053 [S] KOG3790 Uncharacterized conserved protein 115 1e-25
>YPL030w [S] KOG3790 Uncharacterized conserved protein
Length = 567
Score = 684 bits (1765), Expect = 0.0
Identities = 348/547 (63%), Positives = 419/547 (75%), Gaps = 19/547 (3%)
Query: 8 YTVEKSSILGPEWQSLYSTAEPVDFDKSHFEQAMLNVIRQPNVNSTVILRADMLIDNEYD 67
+ V SILGP+W SLY T V F KSHFEQAM+NVIR+PN+NSTVILRAD+L + +
Sbjct: 23 FIVNDKSILGPQWLSLYQTDGKVTFAKSHFEQAMMNVIREPNINSTVILRADILKEINHA 82
Query: 68 LESGSCVKSE-----KKDIALGSDEG---ILKVNIDDLAPRSVPIALA-DVTTKFQFVRR 118
E+GS K + K +I G++ G + K+NI+DL RS + + ++ +FVRR
Sbjct: 83 AEAGSEPKFDESVLKKFEIDNGNESGEEDVKKINIEDLNIRSCETSESLKLSPVHEFVRR 142
Query: 119 IVPRNPFKDAIINQTCLVMNSNSD--ASTSLVIYIPHFDNAELCPFYIPQVAAVGILLHD 176
I+PRN +KDAIINQTCL++NS TSL++Y PH ++ + CPFYIP+ +VGILLH
Sbjct: 143 IIPRNFYKDAIINQTCLILNSKDPNFQETSLIVYTPHINSEKDCPFYIPRTQSVGILLHQ 202
Query: 177 HQLSVHYIPFAGQKELLFDPKQRVVRTAFRLLQTAYKHSKGVKDGYAKRVMHDVVVDKVL 236
LSVHYIPF K D +RVVRTA+RLLQTA KHSKGV GY KRV HD VV+KV
Sbjct: 203 SVLSVHYIPFPEDKTAFTDESERVVRTAYRLLQTANKHSKGVMQGYEKRVNHDQVVNKVN 262
Query: 237 FQDQYIHLKKKYSKFLVDNWAESTDPKKHVFEDIAIAAFLIELWKKIYGAENTTNKMQFR 296
FQ+ YI LKKKYSKFLV+NWAESTDPKKHVFEDIAIAAFLIELW K+YG + +KMQFR
Sbjct: 263 FQNTYIVLKKKYSKFLVENWAESTDPKKHVFEDIAIAAFLIELWIKVYGPD-FRSKMQFR 321
Query: 297 DLGCGNGVLCYILIQEGFKGLGIDARQRKSWSIYPAEVKRCLKEQVIIPSVLLRPHPTMK 356
DLGCGNG LCYIL+ E KGLGIDAR+RKSWSIYP EV+ LKEQVIIPS+LLRPHP +K
Sbjct: 322 DLGCGNGALCYILLSESIKGLGIDARKRKSWSIYPPEVQSSLKEQVIIPSILLRPHPALK 381
Query: 357 LHAPHLQHNGRFFPMQLVSPQLIAPATVMYSSADLLQSPQVNIAEFPPDTFIIGNHSDEL 416
PHL+HNGRFFP++ V+ ++IAPATV+YSS DLL+SPQVN AEFPPDTFIIGNHSDEL
Sbjct: 382 RQVPHLEHNGRFFPVK-VTHEVIAPATVVYSSEDLLKSPQVNTAEFPPDTFIIGNHSDEL 440
Query: 417 TCWIPLLGYPFMVIPCCSHNLSGNRIRYAVRD-VERAKKLGN-----STYQGLVDRVEYL 470
TCWIPLLG+P+MVIPCCSHN SG R+R+ VR R+ ++ N STY GLVD VEY+
Sbjct: 441 TCWIPLLGHPYMVIPCCSHNFSGQRVRFNVRKRSPRSNEIKNQNNSKSTYSGLVDHVEYI 500
Query: 471 ADRVGWKTEKEMLRIPSTRNAAIIGYKNDKLNEFPTDEIYSILMEEGGADGWVANTMNLM 530
+ RVGWK EKEMLRIPSTRNAAIIG +N L FPT +Y ++ E+GGA+GW+ NTM+L+
Sbjct: 501 SSRVGWKVEKEMLRIPSTRNAAIIGVENATLKHFPTQAVYDMIWEDGGAEGWIQNTMSLL 560
Query: 531 KSNPRGH 537
K NPR H
Sbjct: 561 KRNPRNH 567
>SPCC663.10 [S] KOG3790 Uncharacterized conserved protein
Length = 502
Score = 301 bits (771), Expect = 2e-81
Identities = 194/533 (36%), Positives = 292/533 (54%), Gaps = 75/533 (14%)
Query: 19 EWQSLYSTAEPVDFDKSHFEQAMLNVIRQPNVNSTVILRADMLIDNEYDLESGSCVKSEK 78
+WQS+ + F++ M+ ++ P S+VI+R D+++D++ D
Sbjct: 31 QWQSILE--HDTCYAAEVFDKMMIELVYHPERTSSVIMRTDIILDSQED----------- 77
Query: 79 KDIALGSDEGILKVNIDDLAPRSVPIALADVTTKFQFVRRIVPRNPFKDAIINQTCLVMN 138
D L + + + N+D+ S I RRI+PRN DA ++QT +V++
Sbjct: 78 -DSILNKQKSVFE-NLDERYQISRWID-----------RRIIPRNTNLDATMDQTVVVLH 124
Query: 139 SNSDASTSLVIYIPHFDNA-----ELCPFYIPQVAAVGILLHDHQLSVHYIPFAGQKELL 193
+ + +++Y+PH D + P+Y P VA GI H SV + + +K+
Sbjct: 125 EKLE-NDRILMYLPHLDKSLEQPYNHLPYYHPAVA--GIAFHYKGSSVEVL-YLVEKDFQ 180
Query: 194 FDPKQRVVRTAFRLLQTAYKHSKGVKDGYAKRVMHDVVVDKVLFQDQYIHLKKKYSKFLV 253
+ R++RTA LL +KH KG +GY KR++HD VV++ FQD Y+ LK KY+K LV
Sbjct: 181 RELSSRLLRTAHMLLLVLHKHCKGAVEGYQKRMLHDTVVERNKFQDTYVILKDKYAKQLV 240
Query: 254 DNWAESTDPKKHVFEDIAIAAFLIELWKKIYGAENTTNKMQFRDLGCGNGVLCYILIQEG 313
DNW E TDP KHVFED+AIAAFLIELWK+ Y ++ + F D+GCGNG+L Y+L+ EG
Sbjct: 241 DNWVEKTDPGKHVFEDLAIAAFLIELWKQTY---SSNKEFSFVDVGCGNGLLVYLLLMEG 297
Query: 314 FKGLGIDARQRKSWSIYPAEVKRCLKEQVIIPSVLLRPHPTMKLHAPHLQHNGRFFPMQL 373
+ G G DAR+RKSW YP V+ L E+V++P L H+ F ++
Sbjct: 298 YNGYGFDARKRKSWETYPLWVQVKLYEKVLVPYFL---------------HD---FETKI 339
Query: 374 VSPQLIAPATVMYSSADLLQSPQVNIAEFPPDTFIIGNHSDELTCWIPLLG-----YPFM 428
PQL PA S+A+ ++ F ++F+IGNH+DELT ++P+L FM
Sbjct: 340 PFPQL--PAGFTMSAAN------IHDGRFSENSFLIGNHADELTPYLPILARLNQKCYFM 391
Query: 429 VIPCCSHNLSGNRIRYAVRDVERAKKLGNSTYQGLVDRVEYLADRVGWKTEKEMLRIPST 488
IPCC H+L+G +I +A+ K G Y ++ + L++ VGW E E LRIPST
Sbjct: 392 SIPCCVHDLTGAKISWALPKPRNPKHGGR--YAMYIEWLMQLSEEVGWNIEVEPLRIPST 449
Query: 489 RNAAIIGYK---NDKL-NEFPTDEIYSILMEEGGADGWVANTMNLMKSNPRGH 537
RN A+IG K ND L + TD +Y I+ + G+ G+ + M + +N R H
Sbjct: 450 RNYALIGRKLLSNDLLHSSLSTDALYDIVEKNHGSQGFFVHAMQVAAANSRSH 502
>7299200 [S] KOG3790 Uncharacterized conserved protein
Length = 469
Score = 136 bits (342), Expect = 9e-32
Identities = 85/268 (31%), Positives = 134/268 (49%), Gaps = 70/268 (26%)
Query: 237 FQDQYIHLKKKYSKFLVDNWA---ESTDPKKHVFEDIAIAAFLIELWKKIYGAENTTNKM 293
+ D Y LK+++S+ L+++W ESTDP K ++ED+AIAA+LI LW ++ +
Sbjct: 107 YNDLYKELKQRHSQRLLEHWKTAQESTDPLKFIYEDLAIAAYLIVLW-----SQTQSEPT 161
Query: 294 QFRDLGCGNGVLCYILIQEGFKGLGIDARQRKSWSIYPAEVKRCLKEQVIIPSVLLRPHP 353
F DLGCGNG+L ++L EG+KG G D R+RK WS+YP + +R L E+ + P+
Sbjct: 162 AFADLGCGNGLLVHVLNAEGYKGYGYDIRKRKLWSLYPPDTQRSLIEKAVEPN------- 214
Query: 354 TMKLHAPHLQHNGRFFPMQLVSPQLIAPATVMYSSADLLQSPQVNIAEFPPDTFIIGNHS 413
+ +L P + ++IGNHS
Sbjct: 215 SFRLDFPGVD-------------------------------------------WLIGNHS 231
Query: 414 DELTCWIPL----LGYPFMVIPCCSHNLSGNRIRYAVRDVERAKKLGNSTYQGLVDRVEY 469
DEL+ W+P+ L + ++PCC LSG + R R K+ S YQ V
Sbjct: 232 DELSPWLPVLAGRLNINYFLLPCCPFELSGAKFR------RRNTKI--SAYQDFFQYVTQ 283
Query: 470 LADRVGWKTEKEMLRIPSTRNAAIIGYK 497
++ G++ ++ L+IPST+ A++G K
Sbjct: 284 VSHECGYEILQDRLKIPSTKRLALLGIK 311
>Hs22044059 [S] KOG3790 Uncharacterized conserved protein
Length = 528
Score = 125 bits (315), Expect = 1e-28
Identities = 84/265 (31%), Positives = 126/265 (46%), Gaps = 69/265 (26%)
Query: 237 FQDQYIHLKKKYSKFLVDNWAESTDPKKHVFEDIAIAAFLIELWKKIYGAENTTNKMQFR 296
+ Y LK+KY K +V W E TDP+K V+ED+AIAA+L+ LW++ T + F
Sbjct: 73 YSKAYQELKEKY-KEMVKVWPEVTDPEKFVYEDVAIAAYLLILWEEERAERRLTARQSFV 131
Query: 297 DLGCGNGVLCYILIQEGFKGLGIDARQRKSWSIYPAEVKRCLKEQVIIPSVLLRPHPTMK 356
DLGCGNG+L +IL EG G GID R+RK W +Y + + L+E I P+
Sbjct: 132 DLGCGNGLLVHILSSEGHPGRGIDVRRRKIWDMYGPQTQ--LEEDAITPN---------- 179
Query: 357 LHAPHLQHNGRFFPMQLVSPQLIAPATVMYSSADLLQSPQVNIAEFPPDTFIIGNHSDEL 416
D P V+ ++IGNHSDEL
Sbjct: 180 ---------------------------------DKTLFPDVD--------WLIGNHSDEL 198
Query: 417 TCWIPLL------GYPFMVIPCCSHNLSGNRIRYAVRDVERAKKLGNSTYQGLVDRVEYL 470
T WIP++ F V+PCC + G RY+ R ++ + Y+ +D ++ +
Sbjct: 199 TPWIPVIAARSSYNCRFFVLPCCFFDFIG---RYSRRQSKKTQ------YREYLDFIKEV 249
Query: 471 ADRVGWKTEKEMLRIPSTRNAAIIG 495
G+ +++ LRIPST+ ++G
Sbjct: 250 GFTCGFHVDEDCLRIPSTKRVCLVG 274
>CE04053 [S] KOG3790 Uncharacterized conserved protein
Length = 567
Score = 115 bits (289), Expect = 1e-25
Identities = 96/348 (27%), Positives = 150/348 (42%), Gaps = 75/348 (21%)
Query: 152 PHFDNAELCPFYIPQVAAVGILLHDHQLSVHYIPFAGQKELLFDPKQRVVRTAFRLLQTA 211
PHF++ IP ++ QL + Q+ F KQ AF+ L
Sbjct: 127 PHFESPYSIAIKIPTDTSI-------QLQFLKQANSSQEHFEFMKKQ-----AFKQL--- 171
Query: 212 YKHSKGVKDGYAKRVMHDVVVDKVLFQDQYIHLKKKYSKFLVDNWAESTDPKKHVFEDIA 271
Y KG+ + R + ++ DK + Y H+++ Y + ++ W E+++P+K +FED
Sbjct: 172 YTWLKGIDLSKSSRKTNSLL-DKESYIKTYRHIREDYGRGMIKGWTENSNPQKSIFEDCG 230
Query: 272 IAAFLIELWKKIYGAENTTNKMQFRDLGCGNGVLCYILIQEGFKGLGIDARQRKSWSIYP 331
IA+++ EL ++ +F D+GCGNG+L ++L + G G GID R R W
Sbjct: 231 IASYINEL----VNSDLLPKPNKFVDIGCGNGLLVHLLNKIGMSGYGIDVRHRNIWKTTL 286
Query: 332 AEVKRCLKEQVIIPSVLLRPHPTMKLHAPHLQHNGRFFPMQLVSPQLIAPATVMYSSADL 391
+V L+E + P ++++ P L DL
Sbjct: 287 KDVD--LREMPVDPQIVVQNEPHFDL------------------------------DVDL 314
Query: 392 LQSPQVNIAEFPPDTFIIGNHSDELTCWIPL----LGYPFMVIPCCSHNLSGNRIRYAVR 447
L IGNHSDELT WIP+ L F +IPCC N G +YA
Sbjct: 315 L----------------IGNHSDELTPWIPVMAAKLNCNFFLIPCCPFNFFG---KYANN 355
Query: 448 DVERAKKLGNSTYQGLVDRVEYLADRVGWKTEKEMLRIPSTRNAAIIG 495
K S Y+ + +A+R+G+ + + L IPST+ IIG
Sbjct: 356 GSHLGPKRIVSQYESFFEWTVSVAERLGFDVKIDRLAIPSTKRLCIIG 403
Database: KOG eukaryal database 04/03
Posted date: Apr 14, 2003 1:07 PM
Number of letters in database: 30,389,216
Number of sequences in database: 60,738
Lambda K H
0.321 0.137 0.414
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 33,830,124
Number of Sequences: 60738
Number of extensions: 1532470
Number of successful extensions: 3222
Number of sequences better than 1.0e-05: 5
Number of HSP's better than 0.0 without gapping: 4
Number of HSP's successfully gapped in prelim test: 1
Number of HSP's that attempted gapping in prelim test: 3194
Number of HSP's gapped (non-prelim): 8
length of query: 537
length of database: 30,389,216
effective HSP length: 111
effective length of query: 426
effective length of database: 23,647,298
effective search space: 10073748948
effective search space used: 10073748948
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)