ORF STATUS Function Best COG Functional category Pathways and functional systems
r_klactIV3171 good R KOG0255 General function prediction only Synaptic vesicle transporter SVOP and related transporters (major facilitator superfamily)
Only best alignment is shown:
BLASTP 2.2.3 [May-13-2002]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= r_klactIV3171 1070297 1068519 -593
(593 letters)
Database: KOG eukaryal database 04/03
60,738 sequences; 30,389,216 total letters
Searching..................................................done
Color Key for Alignment Scores: 
Score E
Sequences producing significant alignments: (bits) Value
SPBC1271.10c [R] KOG0255 Synaptic vesicle transporter SVOP and r... 220 5e-57
YNR055c [R] KOG0255 Synaptic vesicle transporter SVOP and relate... 185 2e-46
SPBC530.02 [R] KOG0255 Synaptic vesicle transporter SVOP and rel... 84 6e-16
YBR043c [R] KOG0255 Synaptic vesicle transporter SVOP and relate... 80 9e-15
SPCC794.04c [R] KOG0255 Synaptic vesicle transporter SVOP and re... 75 4e-13
SPAC11D3.05 [R] KOG0255 Synaptic vesicle transporter SVOP and re... 72 2e-12
SPBC609.04 [R] KOG0255 Synaptic vesicle transporter SVOP and rel... 69 3e-11
YOR273c [R] KOG0255 Synaptic vesicle transporter SVOP and relate... 68 3e-11
YLL028w [R] KOG0255 Synaptic vesicle transporter SVOP and relate... 65 4e-10
SPBPB2B2.16c [R] KOG0255 Synaptic vesicle transporter SVOP and r... 64 5e-10
SPAC750.02c [R] KOG0255 Synaptic vesicle transporter SVOP and re... 64 5e-10
SPAC1348.05 [R] KOG0255 Synaptic vesicle transporter SVOP and re... 64 5e-10
SPAC17C9.16c [R] KOG0255 Synaptic vesicle transporter SVOP and r... 64 8e-10
SPAPB1A11.01 [R] KOG0255 Synaptic vesicle transporter SVOP and r... 62 2e-09
YHR048w [R] KOG0255 Synaptic vesicle transporter SVOP and relate... 58 5e-08
YBR008c [R] KOG0255 Synaptic vesicle transporter SVOP and relate... 57 6e-08
SPCC1529.01 [R] KOG0255 Synaptic vesicle transporter SVOP and re... 57 1e-07
SPBC36.02c [R] KOG0255 Synaptic vesicle transporter SVOP and rel... 54 5e-07
YGR224w [R] KOG0254 Predicted transporter (major facilitator sup... 54 7e-07
SPBC409.08 [R] KOG0255 Synaptic vesicle transporter SVOP and rel... 52 3e-06
>SPBC1271.10c [R] KOG0255 Synaptic vesicle transporter SVOP and related
transporters (major facilitator superfamily)
Length = 581
Score = 220 bits (560), Expect = 5e-57
Identities = 151/569 (26%), Positives = 241/569 (41%), Gaps = 36/569 (6%)
Query: 21 NVHLVDGHDKSDKNAKIVLVPTPSDDPDDPLNWEMKRKLLALSCSLVYTLGVGVPTAAIY 80
N + H K+ IVL P PSDDP+DPLNW RK L + +L G
Sbjct: 20 NQYAASEHSVLKKDGDIVLQPQPSDDPNDPLNWNKFRKNWHLVLICLVSLVTGAIANDAG 79
Query: 81 SVLNDVSIQTGISLSQLNNATGYLFLFLGIGCFVFQPLALQYGKRPVYVFTMLATALICV 140
S + ++ + GIS ++NA G LF+ +G ++ P YG+R VY+ +L L +
Sbjct: 80 SAQDQMNAELGISYDAMDNAAGVLFICVGYFTYLAMPATFLYGRRCVYLVCLLFGMLGSM 139
Query: 141 WPPYTKSKGEWIGSKVVQGFFGAAIESLPEITVSDLFFEHQRSSGLATYGVTLLFASYIA 200
W K+ IG++ G A E+L + +VS++FFEH+R + Y ++ +Y+
Sbjct: 140 WFALVKTTSNSIGNQAFIGISEACAEALTQFSVSEVFFEHERGIKIGIYILSTSVGTYLG 199
Query: 201 PCIAGFISDGQSWEWVMWWCAIFAAVCTVFLFFFMEETNYDRKLKIDSRTGQPITMDRHD 260
P AG+I+ Q W W+ WW I + + V F EET +DR ID + Q
Sbjct: 200 PLAAGYIASSQGWRWIGWWGLIISGITFVLFLFTFEETTFDRAAAIDRKQIQ-------- 251
Query: 261 GTVVSNVFSATANIDTLLNKENNHINVDETSSDSVGGVTGDVPDVLHSVLSAENSNIMNQ 320
+SN T D L + I D SD++ V ++ + +A
Sbjct: 252 ---ISN-DQLTVKEDFDLKDMQSDIKPDVEKSDAMDDSKMKVDYTVNEISNA-------- 299
Query: 321 LSRVEVVDGATVQQRKSTKTFWSKLSMTSGAK--EKFLLHHYFMAPFY---LFGLPGILW 375
VQ S ++W ++++ + A Y M F +F P +L+
Sbjct: 300 -----------VQPIYSKPSYWKRIALITPANSLSGIGFRQYIMRLFQTLRIFLFPAVLY 348
Query: 376 AGFFYGQSLIWFNVLNATEVLILAAPPYNFSSTACGLAYFSPLIFSFIVFFLVGTFSDWL 435
+G +G W + TE PYN+ A + +I + I G F D+
Sbjct: 349 SGLQWGAQDAWLSFYLTTEEEDWMEAPYNYGDNAVAIMNVPCIIGATIGCIYGGYFGDYF 408
Query: 436 KVRIARYRGGLSLPEDRLYTVIIYCFIGVAACILWGVGAYYEIHWXXXXXXXXXXXXCSM 495
+ A+ G+ E RL+ +I+ C I ++G+G HW
Sbjct: 409 TLWAAKRNNGIKEAESRLWLMILPCIINPIGLFMFGIGTARHWHWGPTYVGLGFIGFGWG 468
Query: 496 FGITISTTYAIDCYKELDTEAMVVVIIIRNVMSFAVSFGITKWIENLGLKNAFISAAFIL 555
IS Y +D Y + EAMV V +I N + +F WI++LG + +IS +
Sbjct: 469 CAGDISMAYLMDAYPGMVLEAMVGVSVINNTFGYVFTFACQSWIDSLGTERTYISIGVLC 528
Query: 556 LACNLTFVGMVIWGPGLRNRTKHYYWSLV 584
T M++ G LR T Y++ +
Sbjct: 529 FIFIATSFPMILCGKRLRKWTAKQYYTFL 557
>YNR055c [R] KOG0255 Synaptic vesicle transporter SVOP and related
transporters (major facilitator superfamily)
Length = 586
Score = 185 bits (469), Expect = 2e-46
Identities = 137/551 (24%), Positives = 234/551 (41%), Gaps = 23/551 (4%)
Query: 37 IVLVPTPSDDPDDPLNWEMKRKLL---ALSCSLVYTLGVGVPTAAIYSVLNDVSIQTGIS 93
+VL+P PS P+DPLNW RKL ++ +T A LN++ GIS
Sbjct: 42 VVLIPQPSYSPNDPLNWSSWRKLAHFGLMAFITAFTAATSNDAGAAQDSLNEIY---GIS 98
Query: 94 LSQLNNATGYLFLFLGIGCFVFQPLALQYGKRPVYVFTMLATALICVWPPYTKSKGEWIG 153
+N G LFL +G P A YG++ Y+ +W K + I
Sbjct: 99 YDSMNTGAGVLFLGIGWSTLFLAPFANLYGRKITYIVCTTLGLFGALWFALAKRTSDTIW 158
Query: 154 SKVVQGFFGAAIESLPEITVSDLFFEHQRSSGLATYGVTLLFASYIAPCIAGFISDGQSW 213
S++ G + E+ ++++SD+FF+HQ S L Y + +++ P IAG+IS ++
Sbjct: 159 SQLFVGISESCAEAQVQLSLSDIFFQHQLGSVLTVYIMCTSIGTFLGPLIAGYISAFTNF 218
Query: 214 EWVMWWCAIFAAVCTVFLFFFMEETNYDRKLKIDSRTGQPITMDRHDGTVVSNVFSATAN 273
WV W I + + + F EET +DR + T DGT + N +
Sbjct: 219 RWVGWVAVIISGGLLITIIFGCEETYFDRGQYMTPLTS--CQSGYEDGTTLQN------S 270
Query: 274 IDTLLNKENNHINVDETSSDSVGGVTGDVPDVLHSVLSAENSNIMNQLSRVEVVDGATVQ 333
+T +++ H++ ++ ++G D+ + ++ E + + E++DG+
Sbjct: 271 DNTAVSRRKRHLDAKLSTPGAMGEKGVDLSETAEFEVNNEEEVTIPETR--ELIDGSKEH 328
Query: 334 QRKSTKTFWSKLSMTS----GAKEKFLLHHYFMAPFYLFGLPGILWAGFFYGQSLIWFNV 389
+ K T+ G K+ F Y +F P + +G F+G ++
Sbjct: 329 LKPYPKRVAILTKATNLKGYGFKQYF---KYLKINLRMFLFPPVWLSGMFWGIQDVFLTF 385
Query: 390 LNATEVLILAAPPYNFSSTACGLAYFSPLIFSFIVFFLVGTFSDWLKVRIARYRGGLSLP 449
T+ PP+N+S + LI + I G SD+ + +AR+ G+
Sbjct: 386 YLTTQESAYYEPPWNYSDFGVAIMNVPTLIGAVIGCICAGIVSDYFVLWMARHNRGILEA 445
Query: 450 EDRLYTVIIYCFIGVAACILWGVGAYYEIHWXXXXXXXXXXXXCSMFGITISTTYAIDCY 509
E RLY I IG A +++G+G + W I+ Y +DCY
Sbjct: 446 EFRLYFSIATAIIGPAGLLMFGIGTARQWPWQAIYVGLGFVGFAWGCSGDIAMAYLMDCY 505
Query: 510 KELDTEAMVVVIIIRNVMSFAVSFGITKWIENLGLKNAFISAAFILLACNLTFVGMVIWG 569
++ E MV II N +S +F + W+ G +N +I+ A I + M +G
Sbjct: 506 PDMVLEGMVCTAIINNTISCIFTFTCSDWLAASGTENTYIALAVINFGITAFALPMYYYG 565
Query: 570 PGLRNRTKHYY 580
+R TK +Y
Sbjct: 566 KRIRLWTKRWY 576
>SPBC530.02 [R] KOG0255 Synaptic vesicle transporter SVOP and related
transporters (major facilitator superfamily)
Length = 541
Score = 84.0 bits (206), Expect = 6e-16
Identities = 62/206 (30%), Positives = 92/206 (44%), Gaps = 1/206 (0%)
Query: 45 DDPDDPLNWEMKRKLLALSCSLVYTLGVGVPTAAIYSVLNDVSIQTGISLSQLNNATGYL 104
DDP +P NW M +K + + + V ++ S + +VS+ G+S+S + +
Sbjct: 85 DDPLNPKNWPMWKKWIVVVQISLIAFVVTFGSSVYSSGIGNVSMDFGVSISVSSLGSCVF 144
Query: 105 FLFLGIGCFVFQPLALQYGKRPVYVFTMLATALICVWPPYTKSKGEWIGSKVVQGFFGAA 164
+ G G F PL+ YG+ VY T+L L + ++ + + QGFFG+
Sbjct: 145 LVGFGFGSLPFAPLSGIYGRFVVYFCTLLMFTLFQIGGGCAQNIWTLVILRFFQGFFGST 204
Query: 165 IESLPEITVSDLFFEHQRSSGLATYGVTLLFASYIAPCIAGFISDGQ-SWEWVMWWCAIF 223
S T+SDLF QR+ L + P I FI W WV W I
Sbjct: 205 PLSNCGGTLSDLFTPIQRTYVLPGFCTFPFLGPIFGPIIGDFICQSYLGWCWVFWINMIM 264
Query: 224 AAVCTVFLFFFMEETNYDRKLKIDSR 249
AV V +FFFM ET+ D L +R
Sbjct: 265 GAVVIVIIFFFMPETHGDTILDYKAR 290
>YBR043c [R] KOG0255 Synaptic vesicle transporter SVOP and related
transporters (major facilitator superfamily)
Length = 689
Score = 80.1 bits (196), Expect = 9e-15
Identities = 107/588 (18%), Positives = 210/588 (35%), Gaps = 69/588 (11%)
Query: 36 KIVLVPTPSDDPDDPLNWEMKRKLLALSCSLVYTLGVGVPTAAIYSVLNDVSIQTGISLS 95
++ ++P D D P M +K++ + +G + T+ I+ +N ++ + S+
Sbjct: 88 QLAIIPEFKDARDYP---PMMKKMIVFLIAFSSMMGP-MGTSIIFPAINSITTEFKTSVI 143
Query: 96 QLNNATGYLFLFLGIGCFVFQPLALQYGKRPVYVFTMLATALICVWPPYTKSKGEWIGSK 155
+N + G L LG+ + L+ G+R Y+ + + +I +
Sbjct: 144 MVNVSIGVYLLSLGVFPLWWSSLSELEGRRTTYITSFALLFAFNIGSALAPDINSFIALR 203
Query: 156 VVQGFFGAAIESLPEITVSDLFFEHQRSSGLATYGVTLLFASYIAPCIAGFISDGQSWEW 215
++ G A+++S+ TV+DL+ R L+ Y + L A ++P + + W
Sbjct: 204 MLCGAASASVQSVGAGTVADLYISEDRGKNLSYYYLGPLLAPLLSPIFGSLLVNRWPWRS 263
Query: 216 VMWWCAIFAAVCTVFLFFFMEET-------------NYDRKLKIDSRTGQPITMDRHDGT 262
W+ I + + L + ET +R++++D+ I D G
Sbjct: 264 TQWFMVILSGCNVILLTVLLPETLRKQDSKGAIAQILAERRIQVDNNERGEIQEDYQRGE 323
Query: 263 VVSNVFSATANIDTLLNKENNHI-------NVDETSSDSVGGVTGDVPDV-LHSVLSAEN 314
+ TL +++N++ ++D S S G + L + + +
Sbjct: 324 --DETDRIENQVATLSTEKHNYVGEVRDQDSLDLESHSSPNTYDGRAGETQLQRIYTEAS 381
Query: 315 SNIMNQLSRVEVVDGATVQ-----------QRKSTKTFWSKLSMTSGAKEKFLLHH---- 359
++ +D T Q R + KL + K +L
Sbjct: 382 RSLYEYQLDDSGIDATTAQVTRIRSTDPKLARSIRENSLRKLQTNLEEQVKKVLSSNGGE 441
Query: 360 ------------------YFMAP---FYLFGLPGILWAGFFYGQSLIWFNVLNATEVLIL 398
YF+ P + P + A F S +N T
Sbjct: 442 IAPKQVSAVRKVWDTFFVYFIKPLKSLHFLEYPPVALAITFSAISFSTVYFVNMTVEYKY 501
Query: 399 AAPPYNFSSTACGLAYFSPLIFSFIVFFLVGTFSDWLKVRIARYRG--GLSLPEDRL-YT 455
+ PPYNF GL Y + F G W+ + + RY+ G+ PE R+ +
Sbjct: 502 SRPPYNFKPLYIGLLYIPNSVTYFFASIYGGR---WVDMLLKRYKEKYGILAPEARISWN 558
Query: 456 VIIYCFIGVAACILWGVGAYYEIHWXXXXXXXXXXXXCSMFGITISTTYAIDCYKELDTE 515
V+ A +++G + HW +M I + +Y +D
Sbjct: 559 VVTSVISFPIALLIFGWCLDKKCHWVTPLIGTALFGYAAMMTIGATLSYLVDSLPGKGAT 618
Query: 516 AMVVVIIIRNVMSFAVSFGITKWIENLGLKNAFISAAFILLACNLTFV 563
+ + +IR +++ F T + +G AF AFI+L + +
Sbjct: 619 GVALNNLIRQILAATAVFVTTPMLNGMGTGWAFTMLAFIVLGASSVLI 666
>SPCC794.04c [R] KOG0255 Synaptic vesicle transporter SVOP and related
transporters (major facilitator superfamily)
Length = 547
Score = 74.7 bits (182), Expect = 4e-13
Identities = 54/208 (25%), Positives = 94/208 (44%), Gaps = 7/208 (3%)
Query: 46 DPDDPLNWEMKRKLLALSCSLVYTLGVGVPTAAIYSVLNDVSIQ---TGISLSQLNNATG 102
DP P NW M +K+ L + + + ++I+S ++ Q G ++ L +AT
Sbjct: 95 DPLAPKNWPMWKKIYTLLVASFIAIVI-TANSSIFSDGGGIAAQQYHVGATVGDLCSAT- 152
Query: 103 YLFLFLGIGCFVFQPLALQYGKRPVYVFTMLATALICVWPPYTKSKGEWIGSKVVQGFFG 162
L G +F PL+ YG+ P+Y T++ + + +K+ + + GFFG
Sbjct: 153 -FLLGFAAGSVLFAPLSEVYGRLPLYSVTLVIFVVFQIGGGCSKNIWSLVIFRFFHGFFG 211
Query: 163 AAIESLPEITVSDLFFEHQRSSGLATYGVTLLFASYIAPCIAGFISDGQ-SWEWVMWWCA 221
S T+SDLF QR+ L + + P + G+I++ + W W W
Sbjct: 212 CTPMSACGGTISDLFNPIQRTGALLVFCAAAFVGPLVGPVMGGYITESKLGWRWDFWINM 271
Query: 222 IFAAVCTVFLFFFMEETNYDRKLKIDSR 249
I+A + V + F M ET+ + L +R
Sbjct: 272 IWAGLTWVIVCFTMPETHSETLLDFKAR 299
Score = 51.2 bits (121), Expect = 4e-06
Identities = 45/184 (24%), Positives = 69/184 (37%), Gaps = 13/184 (7%)
Query: 403 YNFSSTACGLAYFSPLIFSFIVFFLVG-TFSDWLKVRIAR---YRGGLSLPEDRLYTVII 458
Y F++ GLA I +V L+G + + V R R G PEDRL+ +
Sbjct: 369 YGFNAGEVGLA-----ILGILVGILLGLALTPIIYVHYRRRYEMRDGNICPEDRLFPLFF 423
Query: 459 YCFIGVAACILWGVGAYYEIHWXXXXXXXXXXXXCSMFGITISTTYAIDCYKELDTEAMV 518
F A G Y +HW ++ + + +Y +DCY E+ A+
Sbjct: 424 GSFFIPIALFWLGWTCYPSVHWAAPMVSGIFLGWGFLYVLAVCYSYLVDCYHEMAASALS 483
Query: 519 VVIIIRNVMSFAVSFGITKWIENLGLKNAFISAAFILLACNLTFVGMV--IWGPGLRNRT 576
V R ++ NL A AF+ C L + + WG +R R+
Sbjct: 484 VATFTRYAAGGGMTIVARPMYNNLNYHWATSLLAFV--GCGLVPIPFIFFFWGRRIRQRS 541
Query: 577 KHYY 580
H Y
Sbjct: 542 PHAY 545
>SPAC11D3.05 [R] KOG0255 Synaptic vesicle transporter SVOP and related
transporters (major facilitator superfamily)
Length = 546
Score = 72.4 bits (176), Expect = 2e-12
Identities = 59/203 (29%), Positives = 88/203 (43%), Gaps = 8/203 (3%)
Query: 45 DDPDDPL---NWEMKRKLLALSCSLVYTLGVGVPTAAIYSVLNDVS--IQTGISLSQLNN 99
D PDDPL NW K + V T+ V ++ S + D++ + + I +S L +
Sbjct: 89 DGPDDPLNPRNWSHSYKWWIVIQVSVITIVVTFASSVYSSGIIDIASELHSSIPVSTLGS 148
Query: 100 ATGYLFLFLGIGCFVFQPLALQYGKRPVYVFTMLATALICVWPPYTKSKGEWIGSKVVQG 159
T + G+G F PL+ YG+ +Y T+L + V + + QG
Sbjct: 149 CT--FLVGFGVGSLPFAPLSDIYGRFIIYFVTLLIFTIFQVGGGCAHNVWTLAIVRFFQG 206
Query: 160 FFGAAIESLPEITVSDLFFEHQRSSGLATYGVTLLFASYIAPCIAGFISDGQ-SWEWVMW 218
FG+ + T+SDLF QR+ L + I P I FI+ W W W
Sbjct: 207 VFGSTPLANAGGTISDLFTPVQRTYVLPGFCTFPYLGPIIGPIIGDFITQSYLEWRWTFW 266
Query: 219 WCAIFAAVCTVFLFFFMEETNYD 241
I+AA VF+F F ET+ D
Sbjct: 267 INMIWAAAVIVFVFIFFPETHED 289
Score = 50.4 bits (119), Expect = 7e-06
Identities = 39/157 (24%), Positives = 62/157 (38%), Gaps = 4/157 (2%)
Query: 403 YNFSSTACGLAYFSPLIFSFIVFFLVGTFSDWLKVRIARYRGGLSLPEDRLYTVIIYCFI 462
Y F+ GL++ + + L F W +++ + R G+ PEDRLY + I CF+
Sbjct: 367 YGFNKGEQGLSFIGVGV-GIVCAGLCTPFIYWHYLKVNKKRNGVICPEDRLYPLFIGCFL 425
Query: 463 GVAACILWGVGAYY--EIHWXXXXXXXXXXXXCSMFGITISTTYAIDCYKELDTEAMVVV 520
+ + W Y IHW + +S Y ID Y+ + A+
Sbjct: 426 -LPISMFWFAWTCYPHHIHWIVPIIASAFFGFSLLIVFFVSYNYIIDSYQHMAPSALAAA 484
Query: 521 IIIRNVMSFAVSFGITKWIENLGLKNAFISAAFILLA 557
++R S +S NLG A FI +A
Sbjct: 485 TLVRYSASGGISMVARPMYLNLGDHWATSVLGFISVA 521
>SPBC609.04 [R] KOG0255 Synaptic vesicle transporter SVOP and related
transporters (major facilitator superfamily)
Length = 531
Score = 68.6 bits (166), Expect = 3e-11
Identities = 51/209 (24%), Positives = 94/209 (44%), Gaps = 24/209 (11%)
Query: 44 SDDPDDPLNWEMKRKLLALS--CSLVYTLGVGVPTAAIYSVLNDVSIQTGISLSQLNNAT 101
++DP++PLNW + KL+ C L + + VG +AI++ GIS Q
Sbjct: 68 ANDPENPLNWPLWAKLVVTFDICFLTFAVYVG---SAIFT--------PGISEMQETMHV 116
Query: 102 GYLFLFLGIGCFVFQ----PLAL-------QYGKRPVYVFTMLATALICVWPPYTKSKGE 150
G + + LG+ FV PL L Q G++ +YV ++L + + S G
Sbjct: 117 GTVPVVLGLTLFVLGYAIGPLILSPLSEIPQVGRQKIYVLSLLVFVCLQIPTALGSSLGV 176
Query: 151 WIGSKVVQGFFGAAIESLPEITVSDLFFEHQRSSGLATYGVTLLFASYIAPCIAGFISDG 210
+ + + GFFG+ + T++D++ + + + + + P + G +
Sbjct: 177 LLPMRFLAGFFGSPALATGGATLADIWQPWLLPYFMCFWAIGAIGGPVLGPLLGGAMVVA 236
Query: 211 QSWEWVMWWCAIFAAVCTVFLFFFMEETN 239
+SW W W + + + +FFFM ET+
Sbjct: 237 ESWRWQFWLLMMISGFALIVIFFFMPETS 265
>YOR273c [R] KOG0255 Synaptic vesicle transporter SVOP and related
transporters (major facilitator superfamily)
Length = 659
Score = 68.2 bits (165), Expect = 3e-11
Identities = 45/197 (22%), Positives = 88/197 (43%), Gaps = 11/197 (5%)
Query: 45 DDPDDPLNWEMKRKLLALSCS----LVYTLGVGVPTAAIYSVLNDVSIQTGISLSQLNNA 100
DDPD+P NW +K S LV T+G + +++ ++ + ++L+
Sbjct: 78 DDPDNPHNWSSLKKWYTTMTSAFLCLVVTMGSSLYVSSVPELVERYHVSQTLALA----- 132
Query: 101 TGYLFLFLGIGCFVFQPLALQYGKRPVYVFTMLATALICVWPPYTKSKGEWI-GSKVVQG 159
G F LG+ + PL+ +G++PVY+F++ + L + + I + + G
Sbjct: 133 -GLTFYLLGLSTVIGAPLSEVFGRKPVYLFSLPVSMLFTMGVGLSNGHMRIILPLRFLSG 191
Query: 160 FFGAAIESLPEITVSDLFFEHQRSSGLATYGVTLLFASYIAPCIAGFISDGQSWEWVMWW 219
F + S+ T+ D+F Q S + + ++ ++P +AGF ++ + W W W
Sbjct: 192 VFASPALSVGSGTILDIFDVDQVSVAMTYFVLSPFLGPVLSPIMAGFATEAKGWRWSEWI 251
Query: 220 CAIFAAVCTVFLFFFME 236
I + F+ E
Sbjct: 252 QLIAGGLILPFIALMPE 268
>YLL028w [R] KOG0255 Synaptic vesicle transporter SVOP and related
transporters (major facilitator superfamily)
Length = 586
Score = 64.7 bits (156), Expect = 4e-10
Identities = 50/207 (24%), Positives = 89/207 (42%), Gaps = 22/207 (10%)
Query: 45 DDPDDPLNWEMKRKLLAL-----------SCSLVYTLGVGVPTAAIYSVLNDVSIQTGIS 93
+DP P NW MK+K+L CS ++ V IY V+ V+I GI+
Sbjct: 132 NDPLHPFNWPMKKKVLLCLVLCLDSIAIAMCSSIFASAVP-QICEIYHVIEVVAI-LGIT 189
Query: 94 LSQLNNATGYLFLFLGIGCFVFQPLALQYGKRPVYVFTMLATALICVWPPYTKSKGEWIG 153
L L A + ++ PL+ YG++ V V + AL ++
Sbjct: 190 LFVLGFAASPV---------IYAPLSELYGRKGVLVLSAFGFALFQFAVATAENLQTIFI 240
Query: 154 SKVVQGFFGAAIESLPEITVSDLFFEHQRSSGLATYGVTLLFASYIAPCIAGFISDGQSW 213
+ GF GAA ++ +D+F + R +A + + + ++P + +I+ +W
Sbjct: 241 CRFFGGFIGAAPMAVVPAAFADMFDTNVRGKAIALFSLGVFVGPILSPVMGSYIAQRTTW 300
Query: 214 EWVMWWCAIFAAVCTVFLFFFMEETNY 240
W+ + FA+ V + F EET++
Sbjct: 301 RWLEYVVGCFASAVFVAIVLFFEETHH 327
>SPBPB2B2.16c [R] KOG0255 Synaptic vesicle transporter SVOP and related
transporters (major facilitator superfamily)
Length = 485
Score = 64.3 bits (155), Expect = 5e-10
Identities = 51/206 (24%), Positives = 92/206 (43%), Gaps = 13/206 (6%)
Query: 41 PTPSDDPD--DPLNWEMKRK----LLALSCSLVYTLGVGVPTAAIYSVLNDV-SIQTGIS 93
P ++ PD +P W ++ K ++ S + + G V +I ++ + +T ++
Sbjct: 22 PLETNCPDKYNPKTWPIRLKVRNVIVISSMTFLNQYGDSVFAPSISNIAEQFHASRTLVT 81
Query: 94 LSQLNNATGYLFLFLGIGCFVFQPLALQYGKRPVYVFTMLATALICVWPPYTKSKGEWIG 153
L G LF G +F PL+ Q+G+RP+Y+ AL+ + + + ++
Sbjct: 82 LGATLYTLGILF-----GNLIFAPLSEQFGRRPIYLIGYSVFALLQIPIALSVNLAMFLV 136
Query: 154 SKVVQGFFGAAIESLPEITVSDLFFEHQRSSGLATYGVTLLFASYIAPCIAGFISDGQ-S 212
+ G FG+ S +++DLF + R + Y L IAP I+GFIS
Sbjct: 137 FRFFSGLFGSVGLSNGSGSLADLFEKKDRGKYMVIYFTVLSIGPGIAPIISGFISQSSIG 196
Query: 213 WEWVMWWCAIFAAVCTVFLFFFMEET 238
W+W W I + + F ++ET
Sbjct: 197 WQWEFWILLILSGFNLFWAFLLLKET 222
>SPAC750.02c [R] KOG0255 Synaptic vesicle transporter SVOP and related
transporters (major facilitator superfamily)
Length = 485
Score = 64.3 bits (155), Expect = 5e-10
Identities = 51/206 (24%), Positives = 92/206 (43%), Gaps = 13/206 (6%)
Query: 41 PTPSDDPD--DPLNWEMKRK----LLALSCSLVYTLGVGVPTAAIYSVLNDV-SIQTGIS 93
P ++ PD +P W ++ K ++ S + + G V +I ++ + +T ++
Sbjct: 22 PLETNCPDKYNPKTWPIRLKVRNVIVISSMTFLNQYGDSVFAPSISNIAEQFHASRTLVT 81
Query: 94 LSQLNNATGYLFLFLGIGCFVFQPLALQYGKRPVYVFTMLATALICVWPPYTKSKGEWIG 153
L G LF G +F PL+ Q+G+RP+Y+ AL+ + + + ++
Sbjct: 82 LGATLYTLGILF-----GNLIFAPLSEQFGRRPIYLIGYSVFALLQIPIALSVNLAMFLV 136
Query: 154 SKVVQGFFGAAIESLPEITVSDLFFEHQRSSGLATYGVTLLFASYIAPCIAGFISDGQ-S 212
+ G FG+ S +++DLF + R + Y L IAP I+GFIS
Sbjct: 137 FRFFSGLFGSVGLSNGSGSLADLFEKKDRGKYMVIYFTVLSIGPGIAPIISGFISQSSIG 196
Query: 213 WEWVMWWCAIFAAVCTVFLFFFMEET 238
W+W W I + + F ++ET
Sbjct: 197 WQWEFWILLILSGFNLFWAFLLLKET 222
>SPAC1348.05 [R] KOG0255 Synaptic vesicle transporter SVOP and related
transporters (major facilitator superfamily)
Length = 485
Score = 64.3 bits (155), Expect = 5e-10
Identities = 51/206 (24%), Positives = 92/206 (43%), Gaps = 13/206 (6%)
Query: 41 PTPSDDPD--DPLNWEMKRK----LLALSCSLVYTLGVGVPTAAIYSVLNDV-SIQTGIS 93
P ++ PD +P W ++ K ++ S + + G V +I ++ + +T ++
Sbjct: 22 PLETNCPDKYNPKTWPIRLKVRNVIVISSMTFLNQYGDSVFAPSISNIAEQFHASRTLVT 81
Query: 94 LSQLNNATGYLFLFLGIGCFVFQPLALQYGKRPVYVFTMLATALICVWPPYTKSKGEWIG 153
L G LF G +F PL+ Q+G+RP+Y+ AL+ + + + ++
Sbjct: 82 LGATLYTLGILF-----GNLIFAPLSEQFGRRPIYLIGYSVFALLQIPIALSVNLAMFLV 136
Query: 154 SKVVQGFFGAAIESLPEITVSDLFFEHQRSSGLATYGVTLLFASYIAPCIAGFISDGQ-S 212
+ G FG+ S +++DLF + R + Y L IAP I+GFIS
Sbjct: 137 FRFFSGLFGSVGLSNGSGSLADLFEKKDRGKYMVIYFTVLSIGPGIAPIISGFISQSSIG 196
Query: 213 WEWVMWWCAIFAAVCTVFLFFFMEET 238
W+W W I + + F ++ET
Sbjct: 197 WQWEFWILLILSGFNLFWAFLLLKET 222
>SPAC17C9.16c [R] KOG0255 Synaptic vesicle transporter SVOP and related
transporters (major facilitator superfamily)
Length = 531
Score = 63.5 bits (153), Expect = 8e-10
Identities = 50/229 (21%), Positives = 98/229 (41%), Gaps = 17/229 (7%)
Query: 37 IVLVPTPSDDPDDPLNWEMKRKLLALS--CSLVYT--LGVGVPTAAIYSVLNDVSIQT-G 91
I++ DDP++P NW + KL+ C L + +G + T I + + + T
Sbjct: 61 IIVTWDGEDDPENPKNWPLWAKLVVTFDVCFLTFAVYMGSAIFTPGIQEIRETMHVGTVP 120
Query: 92 ISLSQLNNATGYLFLFLGIGCFVFQPLAL--QYGKRPVYVFTMLATALICVWPPYTKSKG 149
+ L GY +G +F PL+ Q G++ +YV +++ + + S G
Sbjct: 121 VILGLTLFVEGY-----AVGPLIFSPLSEVPQIGRQKIYVLSLIVFICLQIPTALGSSLG 175
Query: 150 EWIGSKVVQGFFGAAIESLPEITVSDLFFEHQRSSGLATYGVTLLFASYIAPCIAGFISD 209
+ + + G FG+ S +++D++ + + + + + P + +
Sbjct: 176 VLLPMRFLAGVFGSPALSTGGASLADIWQPWLYPYFMCFWSLGAVGGPVLGPLLGAAMVV 235
Query: 210 GQSWEWVMWWCAIFAAVCTVFLFFFMEETN-----YDRKLKIDSRTGQP 253
+SW W W + +A+ V + FFM ET+ Y R ++ TG P
Sbjct: 236 AKSWRWQFWLLMMISALVLVIITFFMPETSEWHLLYKRAKRLRELTGNP 284
>SPAPB1A11.01 [R] KOG0255 Synaptic vesicle transporter SVOP and related
transporters (major facilitator superfamily)
Length = 351
Score = 62.4 bits (150), Expect = 2e-09
Identities = 49/216 (22%), Positives = 96/216 (43%), Gaps = 8/216 (3%)
Query: 31 SDKNAK-IVLVPTPSD------DPDDPLNWEMKRKLLALSCSLVYTLGVGVPTAAIYSVL 83
SDK+ K I L+P S D DPL W ++ +++ T+ ++ +
Sbjct: 4 SDKDFKDIELLPVKSIESKDSIDQCDPLTWPIRIRIINTIIISFMTMLCMYGSSVFMPSI 63
Query: 84 NDVSIQTGISLSQLNNATGYLFLFLGIGCFVFQPLALQYGKRPVYVFTMLATALICVWPP 143
++ + G + + + + +G +F PL+ YG+RP+ +F AL+ +
Sbjct: 64 PELCEKFGEPETLVVLGATLYVIGVMLGPLIFSPLSELYGRRPLNIFGYTLFALMQIPTA 123
Query: 144 YTKSKGEWIGSKVVQGFFGAAIESLPEITVSDLFFEHQRSSGLATYGVTLLFASYIAPCI 203
+ + ++ + GFFG+ + ++SD+F + R + Y + + IAP
Sbjct: 124 LSVNLAMFVVFRFFSGFFGSVGLGIGAGSLSDMFSKRDRGKYIGIYFLGICLGPAIAPIA 183
Query: 204 AGFISDGQ-SWEWVMWWCAIFAAVCTVFLFFFMEET 238
+GFI+ SW W W + + V + F++ET
Sbjct: 184 SGFIAGSSISWRWEFWILLMLSGVSLLAGVVFLKET 219
>YHR048w [R] KOG0255 Synaptic vesicle transporter SVOP and related
transporters (major facilitator superfamily)
Length = 514
Score = 57.8 bits (138), Expect = 5e-08
Identities = 44/179 (24%), Positives = 82/179 (45%), Gaps = 12/179 (6%)
Query: 104 LFLF-LGIGCFVFQPLALQYGKRPVYVFTMLATALICVWPPYTKSKGEWIGSKVVQGFFG 162
L++F LGIG PL+ YG+R +++ + + + ++K+ + + + GFFG
Sbjct: 117 LYVFGLGIGPLFLSPLSELYGRRITFLYALTLSIIWQCLTIWSKTITGVMFGRFLSGFFG 176
Query: 163 AAIESLPEITVSDLFFEHQRSSGLATYGVTLLFASYIAPCIAGFISDGQSWEWVMWWCAI 222
+A S+ ++D+F + Q +A Y + + P I G + QS++W I
Sbjct: 177 SAFLSVAGGAIADIFDKDQIGIPMAIYTTSAFLGPSLGPIIGGALYH-QSYKWTFITLLI 235
Query: 223 FAAVCTVFLFFFMEETNYD----------RKLKIDSRTGQPITMDRHDGTVVSNVFSAT 271
+ C V + F + ET RK K D R + + R +++S +F +T
Sbjct: 236 TSGCCLVMIIFTIPETYKPMLLIRKAKRLRKEKNDQRYYAVLEVTREQTSLLSAIFLST 294
>YBR008c [R] KOG0255 Synaptic vesicle transporter SVOP and related
transporters (major facilitator superfamily)
Length = 548
Score = 57.4 bits (137), Expect = 6e-08
Identities = 50/216 (23%), Positives = 91/216 (41%), Gaps = 13/216 (6%)
Query: 46 DPDDPLNWEMKRKLLALSCSLVYTLGVGVPTAAIYSVLNDV---SIQTGISLSQLNNATG 102
DP++P NW + +K L + ++ T V ++IY+ + G ++ LN
Sbjct: 90 DPENPQNWPLLKKSLVVFQIMLLTC-VTYMGSSIYTPGQEYIQEEFHVGHVVATLN--LS 146
Query: 103 YLFLFLGIGCFVFQPLA--LQYGKRPVYVFTMLATALICVWPPYTKSKGEWIGSKVVQGF 160
L G+G +F PL+ +YG+ +Y+ T+ + V + G I + + G
Sbjct: 147 LYVLGYGLGPIIFSPLSETARYGRLNLYMVTLFFFMIFQVGCATVHNIGGLIVMRFISGI 206
Query: 161 FGAAIESLPEITVSDLFFEHQRSSGLATYGVTLLFASYIAPCIAGFISDGQSWEWVMWWC 220
+ + TV+D+ L + + A +AP + + D ++W ++ W
Sbjct: 207 LCSPSLATGGGTVADIISPEMVPLVLGMWSAGAVAAPVLAPLLGAAMVDAKNWRFIFWLL 266
Query: 221 AIFAAVCTVFLFFFMEETN-----YDRKLKIDSRTG 251
+A + L FF ET Y R LK+ TG
Sbjct: 267 MWLSAATFILLAFFFPETQHHNILYRRALKLRKETG 302
>SPCC1529.01 [R] KOG0255 Synaptic vesicle transporter SVOP and related
transporters (major facilitator superfamily)
Length = 462
Score = 56.6 bits (135), Expect = 1e-07
Identities = 44/195 (22%), Positives = 84/195 (42%), Gaps = 3/195 (1%)
Query: 46 DPDDPLNWEMKRKLLALSCSLVYTLGVGVPTAAIYSVLNDVSIQTGI--SLSQLNNATGY 103
DP +P NW RK L + L + ++ + L+ ++ + I S + + Y
Sbjct: 32 DPKNPKNWIYARKWTQLILVSAFALLGPMASSMVAPCLDQIADRFHIQNSTEKALILSIY 91
Query: 104 LFLFLGIGCFVFQPLALQYGKRPVYVFTMLATALICVWPPYTKSKGEWIGSKVVQGFFGA 163
L +F I + PL+ +G+R + + + + ++K + + + GF A
Sbjct: 92 LLVF-AISPMISAPLSEVFGRRMLLQVGNVIFIVFNMACGLARTKAQMYIFRFLAGFGSA 150
Query: 164 AIESLPEITVSDLFFEHQRSSGLATYGVTLLFASYIAPCIAGFISDGQSWEWVMWWCAIF 223
L T+SDLF +R +A + L I P ++GFI++ +++W+ W IF
Sbjct: 151 TPMGLGSGTISDLFTPDERGKAVAVMSLAPLLGPTIGPVVSGFIAEYTTYKWIFWSTTIF 210
Query: 224 AAVCTVFLFFFMEET 238
+ + ET
Sbjct: 211 SGFIFALSLPLLAET 225
>SPBC36.02c [R] KOG0255 Synaptic vesicle transporter SVOP and related
transporters (major facilitator superfamily)
Length = 577
Score = 54.3 bits (129), Expect = 5e-07
Identities = 42/201 (20%), Positives = 84/201 (40%), Gaps = 8/201 (3%)
Query: 44 SDDPDDPL---NWEMKRKLLALSCSLVYTLGVGVPTAAIYSVLNDVSIQTGISLSQLNNA 100
S DP PL NW KRKL +C L Y +++++V + +I T +S +
Sbjct: 117 SIDPKSPLIAVNWPFKRKLKT-TCILAYVALCSSFASSVFAVPAE-AITTVFHISLTVSL 174
Query: 101 TGYLFLFLGI--GCFVFQPLALQYGKRPVYVFTMLATALICVWPPYTKSKGEWIGSKVVQ 158
LG G ++ PL+ G++P + ML + + K + +
Sbjct: 175 LTMTVFLLGYCSGPIIWAPLSELSGRKPPILIGMLGFGIFNISVAVGKDIQTIMMCRFFA 234
Query: 159 GFFGAAIESLPEITVSDLFFEHQRSSGLATYGVTLLFASYIAPCIAGFISDGQ-SWEWVM 217
GFF +A ++ ++D++ R + + + + ++P + GF++ W W
Sbjct: 235 GFFASAPLTVVAAALADMYSNKYRGTAITLFSAMVFDGPLVSPIVGGFLTKSYLGWRWTE 294
Query: 218 WWCAIFAAVCTVFLFFFMEET 238
+ + + ++ F +ET
Sbjct: 295 YITSFMGFFALIIVYLFCDET 315
>YGR224w [R] KOG0254 Predicted transporter (major facilitator superfamily)
Length = 613
Score = 53.9 bits (128), Expect = 7e-07
Identities = 48/209 (22%), Positives = 89/209 (41%), Gaps = 13/209 (6%)
Query: 31 SDKNAKIVLVPTPSDDPDDPLNWEMKRKLLALSCSLVYTLGVGVPTAAIYSVLNDVSIQT 90
S +N +VL S+ + P + + L+AL+ SL + + +++ +V+ Q
Sbjct: 42 SKQNVSVVLEDNASESNELPKGFILYASLIALALSLFLA---ALDIMIVSTIIEEVAKQF 98
Query: 91 GISLSQLNNATGYLFLFLGIG----CFVFQPLALQYGKRPVYVFTMLATALICVWPPYTK 146
G S S++ G+LF + ++ +A G + +F ++ + +
Sbjct: 99 G-SYSEI----GWLFTGYSLPNALLALIWGRIATPIGFKETMLFAIVIFEIGSLISALAN 153
Query: 147 SKGEWIGSKVVQGFFGAAIESLPEITVSDLFFEHQRSSGLATYGVTLLFASYIAPCIAGF 206
S IG +V+ G G I+SL + S L E QR +A + AS + P + G
Sbjct: 154 SMSMLIGGRVIAGVGGCGIQSLSFVIGSTLVEESQRGILIAVLSCSFAIASVVGPFLGGV 213
Query: 207 ISDGQSWEWVMWW-CAIFAAVCTVFLFFF 234
+ +W W + I +FLFF+
Sbjct: 214 FTSSVTWRWCFYVNLPIGGLAFFLFLFFY 242
>SPBC409.08 [R] KOG0255 Synaptic vesicle transporter SVOP and related
transporters (major facilitator superfamily)
Length = 539
Score = 51.6 bits (122), Expect = 3e-06
Identities = 41/189 (21%), Positives = 77/189 (40%), Gaps = 1/189 (0%)
Query: 39 LVPTPSDDPDDPLNWEMKRKLLALSCSLVYTLGVGVPTAAIYSVLNDVSIQTGISLSQLN 98
LV +DP++P NW K + + + ++ I L DVS + N
Sbjct: 81 LVTWELNDPENPHNWSRLWKWYITIVNSLLVVCSAFGSSVIAGDLEDVSRDLKVGPEVAN 140
Query: 99 NATGYLFLFLGIGCFVFQPLALQYGKRPVYVFTMLATALICVWPPYTKSKGEWIGSKVVQ 158
+ + + GIG V PL+ G+R VY+ T++ ++ + + + +
Sbjct: 141 LSCSLMVVGFGIGPLVISPLSEMIGRRIVYLVTLMIYIVLQIPCALAPNIACLLIVRFFC 200
Query: 159 GFFGAAIESLPEITVSDLFFEHQRSSGLATYGVTLLFASYIAPCIAGFISDGQ-SWEWVM 217
G FG +L +SD++ +R +A + + P + G+I G + W+
Sbjct: 201 GCFGCTPLTLAGGVISDVWETRERGLAIAFFAAGPYAGPTLGPLVGGWIGVGTGDFRWIF 260
Query: 218 WWCAIFAAV 226
W I+ V
Sbjct: 261 WVNMIYMFV 269
Database: KOG eukaryal database 04/03
Posted date: Apr 14, 2003 1:07 PM
Number of letters in database: 30,389,216
Number of sequences in database: 60,738
Lambda K H
0.325 0.140 0.442
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 35,038,914
Number of Sequences: 60738
Number of extensions: 1468034
Number of successful extensions: 4578
Number of sequences better than 1.0e-05: 20
Number of HSP's better than 0.0 without gapping: 2
Number of HSP's successfully gapped in prelim test: 18
Number of HSP's that attempted gapping in prelim test: 4517
Number of HSP's gapped (non-prelim): 35
length of query: 593
length of database: 30,389,216
effective HSP length: 112
effective length of query: 481
effective length of database: 23,586,560
effective search space: 11345135360
effective search space used: 11345135360
T: 11
A: 40
X1: 15 ( 7.0 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 40 (21.6 bits)