ORF STATUS Function Best COG Functional category Pathways and functional systems
r_klactIV3218 good G KOG2533 Carbohydrate transport and metabolism Permease of the major facilitator superfamily
Only best alignment is shown:
BLASTP 2.2.3 [May-13-2002]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= r_klactIV3218 1085849 1084065 -595
(595 letters)
Database: KOG eukaryal database 04/03
60,738 sequences; 30,389,216 total letters
Searching..................................................done
Color Key for Alignment Scores: 
Score E
Sequences producing significant alignments: (bits) Value
YAL067c [G] KOG2533 Permease of the major facilitator superfamily 830 0.0
YGR065c [G] KOG2533 Permease of the major facilitator superfamily 412 e-115
SPBC2G2.01c [G] KOG2533 Permease of the major facilitator superf... 239 1e-62
YCR028c [G] KOG2533 Permease of the major facilitator superfamily 185 2e-46
SPAC1002.16c [G] KOG2533 Permease of the major facilitator super... 122 2e-27
YLR004c [G] KOG2533 Permease of the major facilitator superfamily 97 5e-20
SPAC1039.04 [G] KOG2533 Permease of the major facilitator superf... 94 6e-19
SPCC417.10 [G] KOG2533 Permease of the major facilitator superfa... 93 1e-18
SPBC1773.15 [G] KOG2533 Permease of the major facilitator superf... 89 2e-17
SPCC757.13 [G] KOG2533 Permease of the major facilitator superfa... 87 7e-17
SPAC11D3.18c [G] KOG2533 Permease of the major facilitator super... 85 4e-16
SPBC1683.12 [G] KOG2533 Permease of the major facilitator superf... 84 6e-16
SPBPB10D8.01 [G] KOG2533 Permease of the major facilitator super... 79 1e-14
YIL166c [G] KOG2533 Permease of the major facilitator superfamily 69 2e-11
YGR260w [G] KOG2533 Permease of the major facilitator superfamily 69 2e-11
YJR152w [G] KOG2533 Permease of the major facilitator superfamily 64 6e-10
YLL055w [G] KOG2533 Permease of the major facilitator superfamily 63 1e-09
SPCPB1C11.03 [G] KOG2533 Permease of the major facilitator super... 61 5e-09
SPAC1B3.15c [G] KOG2533 Permease of the major facilitator superf... 51 6e-06
SPAC1B3.16c [G] KOG2533 Permease of the major facilitator superf... 50 7e-06
>YAL067c [G] KOG2533 Permease of the major facilitator superfamily
Length = 593
Score = 830 bits (2145), Expect = 0.0
Identities = 406/591 (68%), Positives = 464/591 (77%), Gaps = 21/591 (3%)
Query: 9 SLTQELLIDPYKRLKWGFIXXXXXXXXX-----XXXXXXXANTAESD--AGLSVTTGSEL 61
S+ +E+++DPYKRLKWGFI +N+ +S A +TT SE
Sbjct: 3 SIVKEIIVDPYKRLKWGFIPVKRQVEDLPDDLNSTEIVTISNSIQSHETAENFITTTSEK 62
Query: 62 ----VESGKKSSQSDTFEVTSDDDTEYEYRDEANRKWWKFFDEQEYRINKKQNDNWKWYN 117
E+ S D VT YEYRDEA+R WW+FFDEQEYRIN+K+ + KWY+
Sbjct: 63 DQLHFETSSYSEHKDNVNVTRS----YEYRDEADRPWWRFFDEQEYRINEKERSHNKWYS 118
Query: 118 WFAPDMSTQEXXXXXXXXXXXAFYSMIAYWVKYLDTVNLNNAYVSGMKEEIGFKGNDLVN 177
WF S +E AFYS IAYWVKYLDTVN+NNAYVSGMKE++GF+GNDLV+
Sbjct: 119 WFKQGTSFKEKKLLIKLDVLLAFYSCIAYWVKYLDTVNINNAYVSGMKEDLGFQGNDLVH 178
Query: 178 TQVMYTVGNIIFQIPFIFILNKVPLNYVLPGLDICWSLLTLGAAYVDTVPHLKAIRFFIG 237
TQVMYTVGNIIFQ+PF+ LNK+PLNYVLP LD+CWSLLT+GAAYV++VPHLKAIRFFIG
Sbjct: 179 TQVMYTVGNIIFQLPFLIYLNKLPLNYVLPSLDLCWSLLTVGAAYVNSVPHLKAIRFFIG 238
Query: 238 AFEAPSYLAYQYLFGCFYKHDEMVRRSAFYYFGQYAGVLSSGGIISAVHATMNGLHGKSG 297
AFEAPSYLAYQYLFG FYKHDEMVRRSAFYY GQY G+LS+GGI SAV++++NG++G G
Sbjct: 239 AFEAPSYLAYQYLFGSFYKHDEMVRRSAFYYLGQYIGILSAGGIQSAVYSSLNGVNGLEG 298
Query: 298 WRWNFIIDAVISVAVGLLGFYMLPGDPYNCYSIFLTDDEIRLARKRLRENNTEKSDFHNK 357
WRWNFIIDA++SV VGL+GFY LPGDPYNCYSIFLTDDEIRLARKRL+EN T KSDF K
Sbjct: 299 WRWNFIIDAIVSVVVGLIGFYSLPGDPYNCYSIFLTDDEIRLARKRLKENQTGKSDFETK 358
Query: 358 FFDKEVWKRIIFDWKIYVLTLWNIFCWNNNNGSSGAFLLWLNSLKNSDGSTRLSIEKKNQ 417
FD ++WK I DWKIY+LTLWNIFCWN++N SSGA+LLWL SLK R SI K NQ
Sbjct: 359 VFDIKLWKTIFSDWKIYILTLWNIFCWNDSNVSSGAYLLWLKSLK------RYSIPKLNQ 412
Query: 418 FSMITPGLGMVYLFLTSLLADKGHTRWGAIIVTQVFNFIGNVILAAWNVPEGAKWFAFML 477
SMITPGLGMVYL LT ++ADK H+RW AII TQVFN IGN ILAAW+V EGAKWFAFML
Sbjct: 413 LSMITPGLGMVYLMLTGIIADKLHSRWFAIIFTQVFNIIGNSILAAWDVAEGAKWFAFML 472
Query: 478 QYFGWAMAPVLYSWQNDICRRDAQARAVILVVMNMLAQTSTAWISVLVWKTVEAPRYLKG 537
Q FGWAMAPVLYSWQNDICRRDAQ RA+ LV MN++AQ+STAWISVLVWKT EAPRYLKG
Sbjct: 473 QCFGWAMAPVLYSWQNDICRRDAQTRAITLVTMNIMAQSSTAWISVLVWKTEEAPRYLKG 532
Query: 538 FTWTAVAAFCLSAWTFVVLYFYKRDERRNAKANGIILYNSKTGENYPPKKD 588
FT+TA +AFCLS WTFVVLYFYKRDER NAK NGI+LYNSK G P KD
Sbjct: 533 FTFTACSAFCLSIWTFVVLYFYKRDERNNAKKNGIVLYNSKHGVEKPTSKD 583
>YGR065c [G] KOG2533 Permease of the major facilitator superfamily
Length = 593
Score = 412 bits (1060), Expect = e-115
Identities = 214/562 (38%), Positives = 322/562 (57%), Gaps = 23/562 (4%)
Query: 50 DAGLSVTTGSELVESGKKSSQSD-TFEVTSDD--------DTEYEYRDEANRKWWKFFDE 100
D S+ EL S KSS++D T E T+ + D YE RDEA RKWWK+FDE
Sbjct: 29 DTNSSIIAEEELHHSVDKSSKTDVTAETTAVEPHPHNLRHDLPYEVRDEAGRKWWKYFDE 88
Query: 101 QEYRINKKQNDNWKWYNWFAPDMSTQ---EXXXXXXXXXXXAFYSMIAYWVKYLDTVNLN 157
EYR+NK+ + KWY + P+ +TQ E A Y + W K +D N
Sbjct: 89 FEYRVNKEYKKSRKWYEFLYPNHTTQTKAERRLLYKLDIIIALYFFMLCWSKSVDLNNYT 148
Query: 158 NAYVSGMKEEIGFKGNDLVNTQVMYTVGNIIFQIPFIFILNKVPLNYVLPGLDICWSLLT 217
NAYVS MKE++ KGND V T + VG I+FQ+PF+++L + P + +LP +D+ W+ T
Sbjct: 149 NAYVSNMKEDLNMKGNDYVYTSTIANVGAIVFQLPFMYLLPRFPSHIILPVMDLGWTWFT 208
Query: 218 LGAAYVDTVPHLKAIRFFIGAFEAPSYLAYQYLFGCFYKHDEMVRRSAFYYFGQYAGVLS 277
+++ L+A RF + AF A Y QY+ GC+Y DE+ R ++ GQ G ++
Sbjct: 209 FACYRANSLAELRAYRFILSAFGAAYYPVSQYILGCWYAPDEINSRVCLFFCGQQLGSVT 268
Query: 278 SGGIISAVHATMNGLHGKSGWRWNFIIDAV-ISVAVGLLGFYMLPGDPYNCYSIFLTDDE 336
SG + S + ++NG+HG +GWRW F+IDA+ IS+ ++GF+++PG P CYS+FLTD+E
Sbjct: 269 SGLLQSRIFKSLNGVHGLAGWRWMFLIDAIAISLPTAIIGFFVIPGVPSKCYSLFLTDEE 328
Query: 337 IRLARKRLRENNTEKSDFHNK---FFDKEVWKRIIFDWKIYVLTLWNIFCWNNNNGSSGA 393
IR+AR R + N + +K + +++WK++ +VL +++ WNN SG+
Sbjct: 329 IRIARARNKRNQIKDGVDKSKLAPLWSRKLWKKVFCTPAFWVLVVFDTCSWNNMTAYSGS 388
Query: 394 FLLWLNSLKNSDGSTRLSIEKKNQFSMITPGLGMVYLFLTSLLADKGHTRWGAIIVTQVF 453
+ LWL S +T+ SI + N S+I LG Y+ + AD +W ++ +
Sbjct: 389 YTLWLKS------NTKYSIAQVNNLSVIPACLGFAYVIFCAFGADLFRCKWIFMVFAAIM 442
Query: 454 NFIGNVILAAWNVPEGAKWFAFMLQYFGWAMAPVLYSWQNDICRRDAQARAVILVVMNML 513
N + +L W++P AKW+AF YF A +P L+S+ ND R D Q +A+ + +
Sbjct: 443 NTVSCALLIKWDIPSKAKWYAFFTTYFSVAASPCLWSFINDFLRFDPQVKAITWIAIYSF 502
Query: 514 AQTSTAWISVLVWKTVEAPRYLKGFTWTAVAAFCLSAWTFVVLYFYKRDERRNAKANGII 573
+Q++ AWI L W TVE+PR+ G+T + + WTFVVL+FYKR+E+++A NGII
Sbjct: 503 SQSTYAWIPTLAWPTVESPRFKTGYTVSLIFGAIYGLWTFVVLFFYKRNEKKHALGNGII 562
Query: 574 LYNSKTGENYPP-KKDEKEETD 594
LY+S GE P K EE D
Sbjct: 563 LYDSNKGEELPEFVKKNMEERD 584
>SPBC2G2.01c [G] KOG2533 Permease of the major facilitator superfamily
Length = 514
Score = 239 bits (609), Expect = 1e-62
Identities = 133/430 (30%), Positives = 224/430 (51%), Gaps = 21/430 (4%)
Query: 141 YSMIAYWVKYLDTVNLNNAYVSGMKEEIGFKGNDLVNTQVMYTVGNIIFQIPFIFILNKV 200
Y ++Y++ YLD ++NNAY+SGM+E++ GN+L + V++T G II Q+P + L +V
Sbjct: 35 YCCVSYFINYLDRSSINNAYLSGMQEDLKMHGNELQDINVVFTCGYIIGQLPGSYALQRV 94
Query: 201 PLNYVLPGLDICWSLLTLGAAYVDTVPHLKAIRFFIGAFEAPSYLAYQYLFGCFYKHDEM 260
P ++I W L+T+ + V +V L +RFF+ EA ++ Y+ G +YK E+
Sbjct: 95 PARLWFSVMNILWGLMTIFSFAVHSVRALMILRFFMAVAEASTFAGTHYILGAWYKESEL 154
Query: 261 VRRSAFYYFGQYAGVLSSGGIISAVHATMNGLHGKSGWRWNFIIDAVISVAVGLLGFYML 320
+R+ + G + +G + +AVH+++NG G SGWRW FIID ++++ + L G ++
Sbjct: 155 CKRAGIFSASGLVGTMFAGYLQTAVHSSLNGKGGLSGWRWLFIIDGILTIPLSLYGLFLF 214
Query: 321 PGDPYNCYSIFLTDDEIRLARKRLRENNTEKSDFHNKFFDKEVWKRIIFDWKIYVLTLWN 380
P P + + T+ E L+ KRL +K + K I+ W+IY L +
Sbjct: 215 PDVPETTKAPYFTEQEKELSFKRLPARPKKKP------LTLKAIKDIVRSWRIYGLCILW 268
Query: 381 IFCWNNN----NGSSGAFLLWLNSLKNSDGSTRLSIEKKNQFSMITPGLGMVYLFLTSLL 436
IF N G ++ W S + S+ + N + + +G+V S++
Sbjct: 269 IFSGETQAIAVNVLMGQWMKW---------SNKFSVAQINNYPTVITAVGVVSTLGASVI 319
Query: 437 ADK--GHTRWGAIIVTQVFNFIGNVILAAWNVPEGAKWFAFMLQYFGWAMAPVLYSWQND 494
+DK G+ RW + V + IL AWNVP+GAK+FA+ +A V +SW ND
Sbjct: 320 SDKLAGNPRWPFGLFLCVITTVSATILLAWNVPDGAKFFAYFASGCTYAGQAVWFSWAND 379
Query: 495 ICRRDAQARAVILVVMNMLAQTSTAWISVLVWKTVEAPRYLKGFTWTAVAAFCLSAWTFV 554
ICR + Q R V++ +MNM W + +++ + PR++KG V + + +
Sbjct: 380 ICRDNDQERGVVVFLMNMCQNIWHIWWAPIMYPNTDTPRFIKGLIGLLVVGGIVFVSSCI 439
Query: 555 VLYFYKRDER 564
V Y RD+R
Sbjct: 440 VSYMQIRDKR 449
>YCR028c [G] KOG2533 Permease of the major facilitator superfamily
Length = 512
Score = 185 bits (469), Expect = 2e-46
Identities = 132/464 (28%), Positives = 214/464 (45%), Gaps = 35/464 (7%)
Query: 144 IAYWVKYLDTVNLNNAYVSGMKEEIGFKGNDLVNTQVMYTVGNIIFQIPFIFILNKVPLN 203
+ YW+ Y+D V NAY+SGMKE++ GNDL + ++ +G I+ +P +L VP
Sbjct: 43 LQYWINYVDRVGFTNAYISGMKEDLKMVGNDLTVSNTVFMIGYIVGMVPNNLMLLCVPPR 102
Query: 204 YVLPGLDICWSLLTLGAAYVDTVPHLKAIRFFIGAFEAPSYLAYQYLFGCFYKHDEMVRR 263
L W LLTLG V + H+ AIRFF FE+ ++ ++ G +YK DE+ R
Sbjct: 103 IWLSFCTFAWGLLTLGMYKVTSFKHICAIRFFQALFESCTFSGTHFVLGSWYKEDELPIR 162
Query: 264 SAFYYFGQYAGVLSSGGIISAVHATMNGLHGKSGWRWNFIIDAVISVAVGLLGFYMLPGD 323
SA + G + SG + +++ +NG +G +GWRW FIID I++ + + GF PG
Sbjct: 163 SAIFTGSGLVGSMFSGFMQTSIFTHLNGRNGLAGWRWLFIIDFCITLPIAIYGFIFFPGL 222
Query: 324 P--------YNCYSIFLTDDEIRLARKRL--RENNTEKSDFHNKFFDKEVWKRIIFDWKI 373
P ++ + E+ AR+RL R+ +T D R++ W
Sbjct: 223 PDQTSAVSKFSMTRYIFNEQELHYARRRLPARDESTR--------LDWSTIPRVLKRWHW 274
Query: 374 YVLTL-WNIFCWNNNNGSSGAFLLWLNSLKNSDGSTRLSIEKKNQFSMITPGLGMVYLFL 432
++ +L W + N S+ F LWL + K ++ ++N + +G+V
Sbjct: 275 WMFSLVWVLGGENLGFASNSTFALWLQNQK-------YTLAQRNNYPSGIFAVGIVSTLC 327
Query: 433 TSLLADK--GHTRWGAIIVTQVFNFIGNVILAAWNVPEGAKWFAFMLQYFG---WAMAPV 487
+++ K W + + I V++ A P K F QY G +A V
Sbjct: 328 SAVYMSKIPRARHWHVSVFISLVMVIVAVLIRA--DPLNPK-VVFSAQYLGGVAYAGQAV 384
Query: 488 LYSWQNDICRRDAQARAVILVVMNMLAQTSTAWISVLVWKTVEAPRYLKGFTWTAVAAFC 547
+SW N IC D Q RA++L MNM + AW S+L + + P++ +G + +A
Sbjct: 385 FFSWANIICHADLQERAIVLASMNMFSGAVNAWWSILFFASDMVPKFERG-CYALLATAI 443
Query: 548 LSAWTFVVLYFYKRDERRNAKANGIILYNSKTGENYPPKKDEKE 591
S VV+ + E + K I N GE+ + E
Sbjct: 444 SSGIVSVVIRSLQIKENLSKKQVPYIDANDMPGEDDDDDNQDNE 487
>SPAC1002.16c [G] KOG2533 Permease of the major facilitator superfamily
Length = 499
Score = 122 bits (306), Expect = 2e-27
Identities = 112/451 (24%), Positives = 201/451 (43%), Gaps = 24/451 (5%)
Query: 143 MIAYWVKYLDTVNLNNAYVSGMKEEIGFKGNDLVNTQVMYTVGNIIFQIPFIFILNKVPL 202
MI Y V +LD N+ NA V+G+ E++ KG+ ++ V I+F++P ++ KV
Sbjct: 64 MILYLVAFLDRSNIGNAKVAGLPEDLKLKGDQFNIIASVFYVTFILFEMPTTLLMKKVQP 123
Query: 203 NYVLPGLDICWSLLTLGAAYVDTVPHLKAIRFFIGAFEAPSYLAYQYLFGCFYKHDEMVR 262
+L + I +SL T+ + L A R +G EA + Y E+
Sbjct: 124 KRMLAFIVISYSLTTIFTGFCHNFGGLLAARLVLGFCEAGLFPCLALYLTMIYSRVELAP 183
Query: 263 RSAFYYFGQYAGVLSSGGIISAVHATMNGLHGKSGWRWNFIIDAVISVAVGLLGFYMLPG 322
R A Y F A + GG+ + M+G+ G +GWRW FII+ +I G+ ++++P
Sbjct: 184 RIA-YLFASSALSGAFGGLFAYAVLHMDGVGGFAGWRWLFIIEGLIGFVCGVAVYFIIPN 242
Query: 323 DPYNCYSIFLTDDEIRLARKRLRENNTEKSDFHNKFFDKEVWKRIIFDWKIYVLTLWNIF 382
D + FL+ + RKR E +D FD + K D+K+Y+ L
Sbjct: 243 DITKAW--FLSKTHQEMMRKRQLE---RAADLEAAHFDWKGVKSAFTDFKVYLYALSEF- 296
Query: 383 CWNNNNGSSGAFLLWLNSLKNSDGSTRLSIEKKNQFSMITPGLGMVYLFLTSLLADKGHT 442
+ F +L ++ + G T LS++ ++ LG S L+D+ H
Sbjct: 297 ---GQDTCLYGFSTFLPAIISGMGYTSLSVQ---YMTIPVYILGAATYIAASFLSDRFHH 350
Query: 443 RWGAIIVTQVFNFIGNVILAAWNVPEGAKWFAFMLQYFG-WAMAPVLYSWQN-DICRRDA 500
R +I+ +F +G ++L A + +FA L G + A + +W + +I
Sbjct: 351 RGIILIIGNIFPIVGYILLLACQNNKSVLYFACYLCSVGVYTGAGLNVTWLSANIAPHYK 410
Query: 501 QARAVILVVMNMLAQTSTAWISVLVWKTVEAPRYLKGFTWTAVAAFCLSAWTFVVLYFYK 560
+A A+ L + S+ ++ +++ P+Y+ G + +A F + V ++F K
Sbjct: 411 RATAISL---QLAIANSSGILAGQIYR--YPPKYIAGHLTSLIAIFISTVLHVVNIFFLK 465
Query: 561 RDERRNAKANGIILYNSKTGENYPPKKDEKE 591
+ K+ L +S T + KD+K+
Sbjct: 466 HQNSKKQKS----LASSSTIDLSEQPKDDKD 492
>YLR004c [G] KOG2533 Permease of the major facilitator superfamily
Length = 523
Score = 97.4 bits (241), Expect = 5e-20
Identities = 97/438 (22%), Positives = 181/438 (41%), Gaps = 39/438 (8%)
Query: 146 YWVKYLDTVNLNNAYVSGMKEEIGFKGNDLVNTQVMYTVGNIIFQIPFIFILNKVPLNYV 205
Y + +LD LN A G+K+ + KGN+ N +++ I + +++ K P++ +
Sbjct: 90 YLLMFLDKALLNYAASMGIKDHL--KGNEFSNLGTIFSAAYIFMEPVVTYLIQKFPISKI 147
Query: 206 LPGLDICWSLLTLGAAYVDTVPHLKAIRFFIGAFEAPSYLAYQYLFGCFYKHDEMVRRSA 265
L W ++ A T L +R +G FE+ S + + G +Y E R
Sbjct: 148 LGTFITVWGIVLACHAACKTYASLMVVRTLLGLFESSSAVGCIAISGMYYTKSEQSARIG 207
Query: 266 FYYFGQYAGVLSSGGIISAVHATMNGLHGKSGWRWNFIIDAVISVAVGLLGFYMLPGDPY 325
F+ G + GG+IS +G + W+ F++ +++VA G+L F LP +
Sbjct: 208 FWATQAGTGYI-VGGLISFGFLHYHGT-AFTSWQIMFLVVGLVTVAFGVLTFLYLPDNVT 265
Query: 326 NCYSIFLTDDEIRLARKRLRENNTEKSDFHNKFFDKEVWKRII----FDWKIYVLTLWNI 381
N + FL +E + +R N T K F K+ K + F W + +LT
Sbjct: 266 NAW--FLNKEEKIQVVEHIRANQT---GLETKKFKKQQVKELFLHDKFTWPMLLLTA--- 317
Query: 382 FCWNNNNGSSGAFLLWLNSLKNSDGSTRLSIEKKNQFSMITPGLG----MVYLFLTSLLA 437
C + G+ G F + + D K + +++ +G M+ L T +L+
Sbjct: 318 -CSQISTGAIGTFSVTITGTFGFD---------KYETALLQLPIGAITAMIILITTQMLS 367
Query: 438 DKGHTRWGAIIVTQVF--NFIGNVILAAWNVPEG-AKWFAFMLQYFGWAMAPVLYSWQND 494
GH +I T ++ IG ++L + + F+ L Y G + +Y W +
Sbjct: 368 RWGHI---TLITTSMYIPAIIGCIVLISLPLSHKIGNLFSLYLLYSGSCVITNIYIWNS- 423
Query: 495 ICRRDAQARAVILVVMNMLAQTSTAWISVLVWKTVEAPRYLKG-FTWTAVAAFCLSAWTF 553
C + V + M+ + I+ +++ APRY+ C+ +
Sbjct: 424 -CNTSGYTKRVFRNAITMIVYNVSCIIAPQMFRAYSAPRYIPAKIALLVTQCVCVPLQLY 482
Query: 554 VVLYFYKRDERRNAKANG 571
+ K +E+R+ + G
Sbjct: 483 IGYICKKENEKRDKEQEG 500
>SPAC1039.04 [G] KOG2533 Permease of the major facilitator superfamily
Length = 507
Score = 94.0 bits (232), Expect = 6e-19
Identities = 105/441 (23%), Positives = 196/441 (43%), Gaps = 37/441 (8%)
Query: 144 IAYWVKYLDTVNLNNAYVSGMKEEIGFKGNDLVNTQVMYTVGNIIFQIPFIFILNKVPLN 203
+ Y LD N++NA +GM +++GF G+ ++ + ++ PF ++ +
Sbjct: 67 LLYLFNALDKSNVSNAKTNGMDKDLGFVGDQYNIMISIFYIPFVLCAFPFSYLYKRFGAA 126
Query: 204 YVLPGLDICWSLLTLGAAYVDTVPHLKAIRFFIGAFEAPSYLAYQYLFGCFYKHDEMVRR 263
+LP + + ++L A V + A+R+F+G E+ Y FY+ E+ RR
Sbjct: 127 RILPFFMLSFGAMSLCQAAVKNFGGMMAVRWFLGMAESAVLPGVVYYLTTFYRRTELARR 186
Query: 264 SAFYYFGQYAGVLSS-GGIISAVHATMNGLHGK-SGWRWNFIIDAVISVAVGLLGFYMLP 321
A +Y A V S+ GG+++ + + GK GW++ F+I+ ++ ++ F +LP
Sbjct: 187 LAIFYAA--ANVSSAFGGLLA--YGVFHIKGGKLQGWQYLFLIEGGVTFLCAIVIFLVLP 242
Query: 322 GDPYNCYSIFLTDDEIRLARKRLRENNTEKSDFHNKFFDKEVWKRIIFDWKIYVLTLWNI 381
+ FLTD+E LA+ R+ ++D + +K +K+ + +K + LW +
Sbjct: 243 VSVET--ANFLTDEEKTLAKMRI------ENDSSSAISEKLSFKQSLTVFKHPIAILWLL 294
Query: 382 FCWNNNNGSSGAFLLWLNSLKN----SDGSTRLSIEKKNQFSMITPGLGMVYLFLTSLLA 437
A + LNS+ N + S N ++ G ++L + + ++
Sbjct: 295 --------EEMALGVPLNSINNWLPQIVAAMGFSSVNTNLMTVAPAISGAIWLLVFAFIS 346
Query: 438 DKGHTRWGAIIVTQVFNFIGNVILAAWNVPE--GAKWFAFMLQYFGWAMAPVLYS-WQND 494
D R +I IG ++ + ++ G +FA L G A + VL S W N+
Sbjct: 347 DFLKNRGIVLIAAISTTMIGFIVYGSIDIMNHIGVSYFACFLMTAGAAASSVLTSTWYNN 406
Query: 495 ICRRDAQARAVILVVMNMLAQTSTAWISVLVWKTVEAPRYLKGFTWTA---VAAFCLSAW 551
+++ RAV V LA +S +++ +AP+Y+ TA L A
Sbjct: 407 NTPNESR-RAVFTSVGVPLANV-MGLVSANIFRPQDAPKYVPALGITAGFGGLGILLVAS 464
Query: 552 TFVVLYFYKRDERRNAKANGI 572
V ++F D RR A G+
Sbjct: 465 ISVYMFF---DNRRRDNAQGV 482
>SPCC417.10 [G] KOG2533 Permease of the major facilitator superfamily
Length = 508
Score = 93.2 bits (230), Expect = 1e-18
Identities = 97/432 (22%), Positives = 184/432 (42%), Gaps = 28/432 (6%)
Query: 144 IAYWVKYLDTVNLNNAYVSGMKEEIGFKGNDLVNTQVMYTVGNIIFQIPFIFILNKVPLN 203
+ Y +++LD + + A + G+KE++ +G + + +G ++F+ P +L + PL+
Sbjct: 71 LVYCIQFLDKTSNSYAVIMGLKEDLKMEGQMYSWSGTAFYLGYLVFEFPASLLLQRFPLS 130
Query: 204 YVLPGLDICWSLLTLGAAYVDTVPHLKAIRFFIGAFEAPSYLAYQYLFGCFYKHDEMVRR 263
L + W L L V P A+R +G E+ + + L +YK E R
Sbjct: 131 KTLCVFLVIWGFL-LCMTSVANYPGFIALRVLLGMMESAASPGFILLTAQWYKRSEQQLR 189
Query: 264 S----AFYYFGQYAGVLSSGGIISAVHATMNGLHGKSGWRWNFIIDAVISVAVGLLGFYM 319
+ AF GQ G + G+ M GW+ FII V+++ +G + +
Sbjct: 190 TSVWVAFNGLGQILGSCMAYGLAKRTSLPMR------GWKLIFIICGVLAIFLGFVILAV 243
Query: 320 LPGDPYNCYSIFLTDDEIRLARKRLRENNTEKSDFHNKFFDKEVWKRIIFDWKIYVLTLW 379
+P +P+ + FLT+++ +L KRLR N + H K + +K + D + +++ +
Sbjct: 244 VPDNPFKAW--FLTEEDRKLVVKRLRANKQGVGNNHFKLYQ---FKETMLDIRTWIMFVS 298
Query: 380 NIFCWNNNNGSSGAFLLWLNSLKNSDGSTRLSIEKKNQFSMITPGLGMVYLFLTSLLADK 439
++ N NG G F L +K + G L + G++ SL
Sbjct: 299 SVLL-NIPNGGIGTFSSLL--IKGTMGYDTLQTLLMGLPAGACEFGGLIAFGFLSLFI-- 353
Query: 440 GHTRWGAIIVTQVFNFIGNVILAAWNVPEGAKWFAFMLQYFGWAMAPVLYSWQNDICRRD 499
H R +T IG+ +L+ P ++L AM V+++ +
Sbjct: 354 -HKRMVLATITTCIALIGSCLLSFAGPPRAQLAGYYLLMVSPGAMI-VMFAIISS--NAS 409
Query: 500 AQARAVILVVMNMLAQTSTAWISVLVWKTVEAPRYLKGFTWTAVAAFCLSAWTFVVLYF- 558
+ V + V+ ++ I +K +AP Y+ T V + + TF LY+
Sbjct: 410 GYTKKVTVGVIYLIGYCVGNLIGPQTFKAADAPEYMPAKN-TMVGCYAATLVTFPALYYV 468
Query: 559 -YKRDERRNAKA 569
++ ++RR+ A
Sbjct: 469 NWRENKRRDQLA 480
>SPBC1773.15 [G] KOG2533 Permease of the major facilitator superfamily
Length = 497
Score = 89.0 bits (219), Expect = 2e-17
Identities = 95/448 (21%), Positives = 180/448 (39%), Gaps = 25/448 (5%)
Query: 149 KYLDTVNLNNAYVSGMKEEIGFKGNDLVNTQVMYTVGNIIFQIPFIFILNKVPLNYVLPG 208
+Y+D N + + G++ ++ GN + +G ++F +P +L K PL+ V
Sbjct: 63 QYMDKSTSNYSSIMGIRTDLNMVGNQYNWVGTSFYLGFMVFSLPLSTLLQKFPLSKVTSA 122
Query: 209 LDICWSLLTLGAAYVDTVPHLKAIRFFIGAFEAPSYLAYQYLFGCFYKHDEMVRRSAFYY 268
+ W +L V + A R +G E+ A+ +Y+ +E R AF
Sbjct: 123 FIVAWGILMTLTCLVHSYASYIATRTLLGILESVITPAFVLFIAQWYRKEEQFFRMAFLV 182
Query: 269 FGQYAGVLSSGGIISAVH-ATMNGLHGKSGWRWNFIIDAVISVAVGLLGFYMLPGDPYNC 327
G L G + ++ + S WR FII +I++ G+ F +P +P
Sbjct: 183 AWNGLGGLIGGSMSYGLYKRELENNLTMSPWRILFIITGLITIINGVFIFIHIPDEPSKA 242
Query: 328 YSIFLTDDEIRLARKRLRENNTEKSDFHNKFFDKEVWKRIIFDWKIYVLTLWNIFCWNNN 387
+ FL++ E L KRL +T+ + +K F K D ++Y+ I N
Sbjct: 243 W--FLSEKEKDLVLKRL---DTDHAGLGSKKFKKYQILEACRDVRMYLYFFLQIAVAIPN 297
Query: 388 NGSSGAFLLWLNSLKNSDGSTRLSIEKKNQFSMITPGLGMVYLFLTSLLADKGHTRWGAI 447
G S + L +L G L +M T + L L L+ + + R
Sbjct: 298 GGLSNFSSIMLKNLGYVKGKALL-------MNMPTSSISFAALTLFGLIPEFTNRRMDIA 350
Query: 448 IVTQVFNFIGNVILAAWNVPEGAKWFAFMLQYFGWAMAPVLYSWQNDICRRDAQARAVIL 507
+V N ++ A+ P A+ + L FG + P + + V +
Sbjct: 351 LVGLAINLTSGSLI-AFAKPTHAQLAGYWL--FGISPIPYICILSCISSNSAGHTKKVFM 407
Query: 508 VVMNMLAQTSTAWISVLVWKTVEAPRYLKGFTWTAVAAFCLSAWTFVVLYFYK-RDERRN 566
++M+ + +++ +AP+Y +G + V +C++ + + +Y R+ RR
Sbjct: 408 SAVSMIGYCVGNMVGPQTFRSTQAPKY-QGAKVSFVVCYCVAIFIIIAIYAVNVRENRRR 466
Query: 567 AKANGIILYNSKTGENYPPKKDEKEETD 594
+ N + N ++D+K+ TD
Sbjct: 467 DEKNEYL-------SNELSEEDKKDLTD 487
>SPCC757.13 [G] KOG2533 Permease of the major facilitator superfamily
Length = 522
Score = 87.0 bits (214), Expect = 7e-17
Identities = 67/246 (27%), Positives = 118/246 (47%), Gaps = 13/246 (5%)
Query: 144 IAYWVKYLDTVNLNNAYVSGMKEEIGFKGNDLVNTQVMYTVGNIIFQIPFIFILNKVPLN 203
I Y ++YLD L+ A + GMK + G+ + ++ G ++ Q P ++ K L+
Sbjct: 83 ITYMIQYLDKTALSYAALYGMKTDTHIDGHTYSSMTTLFYAGYLVAQYPAAILMQKCRLS 142
Query: 204 YVLPGLDICWSLLTLGAAYVDTVPHLKAIRFFIGAFEAPSYLAYQYLFGCFYKHDEM-VR 262
Y + WS + A P L +RF G FEA A+ + +Y+ +E +R
Sbjct: 143 YFIFCNVFLWSAMVCLMAACRNGPSLLGLRFLAGIFEASITPAFINITAMWYRREEQPMR 202
Query: 263 RSAFYYFGQYAGVLSSGGIISAVHATMNGLHGK-SGWRWNFIIDAVISVAVGLLGFYMLP 321
+Y F A ++ G I+S + +HGK + WR+ FI+ ++S+ G++ F +P
Sbjct: 203 TLCWYAFNGIAQII--GSILS---YGLGHIHGKVASWRYVFIVIGLMSLGWGVV-FVFIP 256
Query: 322 GDPYNCYSIFLTDDEIRLARKRLRENNTEKSDFHNKFFDKEVWKRIIFDWKIYVLTLWNI 381
+P + FL+ E R+A +R+R+N T NK F + D ++ ++TL+
Sbjct: 257 SNPSK--ARFLSSREKRIALERVRDNRT---GLENKQFKWKHAYEAFLDPQVIMITLFTG 311
Query: 382 FCWNNN 387
C N
Sbjct: 312 VCMITN 317
>SPAC11D3.18c [G] KOG2533 Permease of the major facilitator superfamily
Length = 498
Score = 84.7 bits (208), Expect = 4e-16
Identities = 95/426 (22%), Positives = 181/426 (42%), Gaps = 25/426 (5%)
Query: 146 YWVKYLDTVNLNNAYVSGMKEEIGFKGNDLVNTQVMYTVGNIIFQIPFIFILNKVPLNYV 205
Y + +LD N+ NA V+GM E + G L ++ V I+ + P + ++ ++ + +
Sbjct: 69 YLMAFLDRSNIGNAAVAGMTEALSLYGERLNVAVSIFYVLYILVETPSVVLVKRIKASRM 128
Query: 206 LPGLDICWSLLTLGAAYVDTVPHLKAIRFFIGAFEAPSYLAYQYLFGCFYKHDEMVRRSA 265
L + WS+ L + ++ + L A R +G E + A Y E +R +
Sbjct: 129 LAFISFAWSMTVLFSGFMSSYGGLIATRLILGLLEGCLFPALNLYLTTHYTRKEQCQRLS 188
Query: 266 FYYFGQYAGVLSSGGIISAVHATMNGLHGKSGWRWNFIIDAVISVAVGLLGFYMLPGDPY 325
+ + AG+ + G + A K GW+W +I++ ++S L + LP
Sbjct: 189 YLFAS--AGLAGAFGGLFAYALEQVHAGNKEGWQWIYIVEGLVSFIGVPLCLFALPDKME 246
Query: 326 NCYSIFLTDDEIRLARKRLRENNTEKSDFHNKFFDKEVWKRIIFDWKIYVLTLWNIFCWN 385
N + FLT +E +A R N + H F+ ++ D K+YV + + FC +
Sbjct: 247 NAW--FLTREEREVAIIRRDINARYHGEQH---FEWSEVRKAFKDPKVYV-SATSQFCAD 300
Query: 386 NNNGSSGAFLLWLNSLKNSDGSTRLSIEKKNQFSMITPGLGMVYLFLTSLLADKGHTRWG 445
+FL + G + N ++ G++ + L+D+ R
Sbjct: 301 MVLYGFSSFLPVIIKGLGFVGL------QTNYMTIPVYIAGVISFLFVAWLSDRTQLRAV 354
Query: 446 AIIVTQVFNFIGNVILAAWNVPEGAKWFAFMLQYFGWAMAPVL-YSWQNDICRRDAQARA 504
+I +G +I+ A + AK+ A + G + P L W N+ + RA
Sbjct: 355 YLISASTVVAVGYIIMLA-SDSNAAKYTATYIIAIGCYIGPGLNLGWLNNNVAGHYK-RA 412
Query: 505 VILVVMNMLAQTSTAWISVLVWKTVEAPRYLKGFTWTAVAAFCLSAWTFVVLYF------ 558
+ + LA S+ ++ ++++ AP+Y+ G +T + + +VV++F
Sbjct: 413 TAIGIQQTLA-NSSGIVAGQIYRSKNAPKYILGNAFT-LGCVIVGGLAYVVMFFSLRYVN 470
Query: 559 YKRDER 564
KRDER
Sbjct: 471 KKRDER 476
>SPBC1683.12 [G] KOG2533 Permease of the major facilitator superfamily
Length = 482
Score = 84.0 bits (206), Expect = 6e-16
Identities = 77/321 (23%), Positives = 136/321 (41%), Gaps = 14/321 (4%)
Query: 144 IAYWVKYLDTVNLNNAYVSGMKEEIGFKGNDLVNTQVMYTVGNIIFQIPFIFILNKVPLN 203
+ Y++ +LD N+ NA V G+KE++ + ++ I + P + ++ K +
Sbjct: 50 VLYFLSFLDRANIGNAAVVGLKEDLKLQAYQYSAAVSVFYATYITAETPSVLLVKKFGPH 109
Query: 204 YVLPGLDICWSLLTLGAAYVDTVPHLKAIRFFIGAFEAPSYLAYQYLFGCFYKHDEMVRR 263
Y L + I WSL+T+ +V L R +G E + YK +E +R
Sbjct: 110 YYLSAMIIGWSLVTIFTCFVRHYWSLVLTRLLLGICEGGFFPCLSLYISMTYKREEQGKR 169
Query: 264 SAFYYF-GQYAGVLSSGGIISAVHATMNGLHGKSGWRWNFIIDAVISVAVGLLGFYMLPG 322
A+ Y ++G GG+I+ + G W W +II+ +IS L + LP
Sbjct: 170 LAYLYVCSCFSGAF--GGLIATGLTKIPKSSGLPNWGWLYIIEGLISAISALWILFCLPD 227
Query: 323 DPYNCYSIFLTDDEIRLARKRLRENNTEKSDFHNKFFDKEVWKRIIFDWKIYVLTLWNIF 382
DP + + E+ R R+ + FD +++ D K+Y+ + F
Sbjct: 228 DPSTARFLNPREKELMKIRAEQRQKYMGSPN-----FDWTQFRKAFKDPKMYMSCVIQ-F 281
Query: 383 CWNNNNGSSGAFLLWLNSLKNSDGSTRLSIEKKNQFSMITPGLGMVYLFLTSLLADKGHT 442
C + FL + LK G + L+ + S+ LG + +++ LL+D+ +
Sbjct: 282 CQDLVLYGISTFL--PSILKLELGYSSLAAQ---YMSVPVYALGGISVYVICLLSDRTNI 336
Query: 443 RWGAIIVTQVFNFIGNVILAA 463
R II F G +IL A
Sbjct: 337 RGWFIIGMNFFGLAGFIILLA 357
>SPBPB10D8.01 [G] KOG2533 Permease of the major facilitator superfamily
Length = 552
Score = 79.3 bits (194), Expect = 1e-14
Identities = 94/442 (21%), Positives = 178/442 (40%), Gaps = 23/442 (5%)
Query: 143 MIAYWVKYLDTVNLNNAYVSGMKEEIGFKGNDLVNTQVMYTVGNIIFQIPFIFILNKVPL 202
MI + Y+D L+ + + G+ E+ N + ++ VG +I QIP +L + P+
Sbjct: 94 MILDMMLYIDKATLSYSSILGLFEDTHINSNQYNDINTLFYVGFVIGQIPGHMLLQRFPV 153
Query: 203 NYVLPGLDICWSLLTLGAAYVDTVPHLKAIRFFIGAFEAPSYLAYQYLFGCFYKHDEMVR 262
+ + W+++ L A+RFF+G E+ + G F+ H E
Sbjct: 154 SKFVAASTALWTIIIFLHCAAYNFSGLMALRFFLGLVESSLLPTMEATIGMFFPHSEQAL 213
Query: 263 RSAFYYFGQYAGVLSSGGIISAVHATMNGLHGKSGWRWNFIIDAVIS--VAVGLLGFYML 320
F+Y Y + +G I V N + S W+ II I+ + +GL +Y
Sbjct: 214 LQPFFYISCYGCNIPAGFIAYGVQYAKNTI---SPWKLFMIIVGGITFFLTIGLFFYY-- 268
Query: 321 PGDPYNCYSI-FLTDDEIRLARKRLRENNTEKSDFHNKFFDKEVWKRIIFDWKIYVLTLW 379
P N + FLT E R+R +N S +K F K + D ++ T +
Sbjct: 269 ---PDNTSTARFLTKKERLYTVDRVRRSN--HSGIESKTFKKYQVIEALKDPVTWLFT-F 322
Query: 380 NIFCWNNNNGSSGAFLLWLNSLKNSDGSTRLSIEKKNQFSMITPGLGMVYLFLTSLLADK 439
++FC +N + L SL SD ++ L ++ ++ ++ ++ S++ ++
Sbjct: 323 HVFCNQLSNNLAYQQNLLFTSLNVSDLNSTLVGVASAGYNCVS---AIIATYMMSVIKNQ 379
Query: 440 GHTRWGAIIVTQVFNFIGNVILAAWNVPEGAKWFAFMLQYFGWAMAPVLYSWQNDICRRD 499
+ + I V + +W+ G + FG + W C
Sbjct: 380 SAFHGAIWYIPSIAGGIACVAM-SWDHKIGELAAIIIASNFGIPFI-ISLGWTTASCA-- 435
Query: 500 AQARAVILVVMNMLAQTSTAWISVLVWKTVEAPRYLKGFTWTAVAAFCLSAWTFVVLYFY 559
+ + VM M+ I +W++ +APRY + V A+ +S + +++ +
Sbjct: 436 GYTKKLTRGVMFMIGYAIANIIGPQMWQSRDAPRYYPAWIVQIVIAWSVSPFVLLIIRWI 495
Query: 560 KRDERRNAKANGIILYNSKTGE 581
RRN K ++ N + E
Sbjct: 496 L--VRRNKKRLALLEQNKEQYE 515
>YIL166c [G] KOG2533 Permease of the major facilitator superfamily
Length = 542
Score = 69.3 bits (168), Expect = 2e-11
Identities = 115/547 (21%), Positives = 221/547 (40%), Gaps = 73/547 (13%)
Query: 60 ELVESGKKSSQSDTFEVTSDDDTEYEYRD-EANRKWWKFFDEQEYRINKKQNDNWKWYNW 118
++VE + S +++ S+ + + D +W K ++ Y K + + W
Sbjct: 9 DIVEKAQLSVSAESLTSDSESISHNPFDDFHKAERWRKVYESSGYEGLSKFDPEFTW--- 65
Query: 119 FAPDMSTQEXXXXXXXXXXXAFYSMIAYWVKYLDTV--NLNNAYVSGMKEEIGFKGNDLV 176
T++ + + +LD + N+ A ++ ND
Sbjct: 66 ------TKDEEKKLVRKMDLKIFLWVFIMFAFLDLIRKNIARAVSDNFIVDLKMNTNDYN 119
Query: 177 NTQVMYTVGNIIFQIPFIFILNKVPLNYVLPGLDICWSLLTLGAAYVDTVPHLKAIRFFI 236
Q +Y V + ++P + + V+P + WS++ + A + A R +
Sbjct: 120 LGQTVYLVIFLASELPGNLLSKRFGPERVIPVQIVLWSVICITQAGLKNRGQFIATRCLL 179
Query: 237 GAFEA---PSYLAYQYLFGCFYKHDEMVRRSAFYYFG----QYAGVLSSGGIISAVHATM 289
G + P + Y +Y E+ R +F++ Q G L + GII M
Sbjct: 180 GMVQGGFIPDNILY---LSYYYTGAELTFRLSFFWCAIPLFQILGSLLASGIIE-----M 231
Query: 290 NGLHGKSGWRWNFIIDAVISVAVGLLGFYMLPGDP-------YNCYSIFLTDDEIRLARK 342
G+H +GW++ FII+ +S++VG+ FY++ P ++ T+ E ++
Sbjct: 232 RGIHNLAGWQYLFIIEGFLSLSVGVASFYLMRRGPTQTGESAFHKGKSLFTEYEEKIMVN 291
Query: 343 RLRENNTEKSDFHNKFFDKEVWKRIIFDWKIYVLT---LWNIFCWNNNNGSS----GAFL 395
R+ ++ K D N+ + + F +Y LT LW +F S G++L
Sbjct: 292 RILRDDPSKGDMSNR-------QPVTFKEILYTLTEFDLWPLFIQGITAFISLQTVGSYL 344
Query: 396 LWLNSLKNSDGSTRLSIEKKNQFSMITPGLGMVYLFLTSLLADKGHTRWGAIIVTQVFNF 455
+ LK+ + ST LS N ++ L ++ L L +LL+ K + + + V+
Sbjct: 345 SLI--LKSLNYSTFLS----NILAIPGQALLLINLPLAALLSRKLKEKSLCVGIANVWVL 398
Query: 456 IGNVILAAWNVPEGAKWFAFMLQYFGWAMAP----VLYSWQNDICRRDAQARAVILVVMN 511
V L A + W ++L G P +L W ++I ++R V + N
Sbjct: 399 PFIVSLVALPT-DTNPWIKYIL-LTGILGLPYTHSILAGWVSEI-SNSVRSRTVGTALYN 455
Query: 512 MLAQTSTAWISVLVWKTVEAPRY------LKGFTWTAVAAFCLSAWTFVVLYFYKRDERR 565
M AQ A I+ +++ + P Y L GFT + C++ T Y+ R++ +
Sbjct: 456 MSAQVG-AIIASNMYRNDDKPYYTRGNKILLGFTCFNI---CMAVAT--KFYYISRNKYK 509
Query: 566 NAKANGI 572
+ K N +
Sbjct: 510 DRKWNSM 516
>YGR260w [G] KOG2533 Permease of the major facilitator superfamily
Length = 534
Score = 69.3 bits (168), Expect = 2e-11
Identities = 96/444 (21%), Positives = 183/444 (40%), Gaps = 30/444 (6%)
Query: 146 YWVKYLDTVNLNNAYVSGMKEEIGFKGNDLVNTQVMYTVGNIIFQIPFIFILNKVPLNYV 205
Y++ LD N+ NA V+G+ ++I G ++ ++F +L + +
Sbjct: 100 YFLSNLDKSNIGNAEVAGLSKDIHLVGTQYNTCVTVFFATYVLFDPIGTNLLKIMGPPLM 159
Query: 206 LPGLDICWSLLTLGAAYVDTVPHLKAIRFFIGAFEAPSYLAYQYLFGCFYKHDEMVRRSA 265
+ C+ ++LG A+V L +R +GAFE Y A Y+ ++ R A
Sbjct: 160 MSICLTCFGAISLGTAWVKNYAQLIVVRLLLGAFEGMIYPAINMYLSVCYRREQYALRFA 219
Query: 266 FYYFGQYAGVLSS--GGIISAVHATMNGLHGKSGWRWNFIIDAVISVAVGLLGFYMLPGD 323
F + A LSS GG+I+ + ++G W++ +I++ IS +G + FY
Sbjct: 220 FVF---SAACLSSSFGGLIAYGCSKISG--SLKDWQYIYIVEGCIS--LGFVPFYAFGLS 272
Query: 324 PYNCYSIFLTDDEIRLARKRLRENNTEKSDFHNKFFDKEVWKRI--IFDWKIYVLTLWNI 381
S F +E +R + NT D KF +VW+ + + W V L+ I
Sbjct: 273 KNLEDSWFFNKEEKEYISERYKTMNTFDPD--EKFEWFQVWQAVKDVKTWASAV-ALFGI 329
Query: 382 FCWNNNNGSSGAFLLWLNSLKNSDGSTRLSIEKKNQFSMITPGLGMVYLFLTSLLADKGH 441
+ ++ ++L + S G T + + ++ L + F+ ++ +D+
Sbjct: 330 ------DLTTFGLTVFLPIIITSMGFTNV---RAQLMTVPIYFLTAIVFFICAVWSDRIK 380
Query: 442 TRWGAIIVTQVFNFIGNVILAAWNVPEGAKWFAFMLQYFG-WAMAPVLYSWQNDICRRDA 500
R I+ + IG I+ V G ++F + G + A W +
Sbjct: 381 LRSPFILGACLTTSIGIAIVLGSQV-HGVRYFGVYILCMGIYVNAACNCLWLSG--NTGN 437
Query: 501 QARAVILVVMNMLAQTSTAWISVLVWKTVEAPRYLKGFTWTAVAAFCLSAWTFVVLYFYK 560
+ + +N+ + + +S ++ + PRY+KG + + T V ++ YK
Sbjct: 438 YFKRATALGINLFFGSGSGLVSGQIFVAKDKPRYIKGLSISLAFQVFSIFMTVVQIFLYK 497
Query: 561 RDERRNAKANGIILYNSKTGENYP 584
R+ N K II ++ GE P
Sbjct: 498 RE---NDKKKAIIDRCNELGEPIP 518
>YJR152w [G] KOG2533 Permease of the major facilitator superfamily
Length = 543
Score = 63.9 bits (154), Expect = 6e-10
Identities = 59/260 (22%), Positives = 113/260 (42%), Gaps = 9/260 (3%)
Query: 144 IAYWVKYLDTVNLNNAYVSGMKEEIGFKGNDLVNTQVMYTVGNIIFQI-PFIFILNKVP- 201
I Y V+++D ++ ++A V G++ ++ G+ + G + + P FI +
Sbjct: 91 ILYAVQFMDKISTSSAAVMGLRTDLKMHGDQYSWVTSAFYFGYLFMNLGPVQFIFQRTSH 150
Query: 202 LNYVLPGLDICWS-LLTLGAAYVDTVPHLKAIRFFIGAFEAPSYLAYQYLFGCFYKHDEM 260
++ +L + W LL L AA P +R +G E+ + + ++K +E
Sbjct: 151 MSKMLAVFIVIWGMLLALHAAPTVKYPSFIVLRVLLGCAESVVTPCFTIITAQYWKTEEQ 210
Query: 261 VRRSAFYYFGQYAGVLSSGGIISAVHATMNGLHGKSGWRWNFIIDAVISVAVGLLGFYML 320
R + ++ G + I V+ + + GWR F+I VI++ +G+L F +
Sbjct: 211 FTRVSIWFGMNGLGSILINAIAYGVYIHQDS-YAIKGWRTLFVITGVITIFIGILIFLWI 269
Query: 321 PGDPYNCYSIFLTDDEIRLARKRLRENNTEKSDFHNKFFDKEVWKRIIFDWKIYVLTLWN 380
P DP + FL+ E + +R+R N + F N K + D + ++ L+
Sbjct: 270 PDDPSK--ARFLSKREKLMVVQRIRSN---QQGFGNHEIKKYQIIEALKDVRTWLYFLFT 324
Query: 381 IFCWNNNNGSSGAFLLWLNS 400
+ N G S + LNS
Sbjct: 325 VSSNIPNGGISSFMSILLNS 344
>YLL055w [G] KOG2533 Permease of the major facilitator superfamily
Length = 531
Score = 63.2 bits (152), Expect = 1e-09
Identities = 90/426 (21%), Positives = 166/426 (38%), Gaps = 32/426 (7%)
Query: 150 YLDTVNLNNAYVSGMKEEIGFKGNDLVNTQVMYTVGNIIFQIPFIFILNKVPLNYVLPGL 209
Y+D L+ + G E+ G N ++ VG I Q P ++ K+PL L GL
Sbjct: 71 YMDKATLSYDSILGFFEDTGLTQNTYNTVNTLFYVGFAIGQFPGQYLAQKLPLGKFLGGL 130
Query: 210 DICWSLLTLGAAYVDTVPHLKAIRFFIGAFEAPSYLAYQYLFGCFYKHDEMVRRSAFYYF 269
W++L + + A+RFF+G E+ G F+ E F++
Sbjct: 131 LATWTILIFLSCTAYNFSGVVALRFFLGLTESVVIPILITTMGMFFDASERAAAQPFFFA 190
Query: 270 GQYAGVLSSGGIISAV-HATMNGLHGKSGWRWNFIIDAVISVAVGLLGFYMLPGDPYNCY 328
+ +G I V H T + S W+ II ++ + ++ P +P +
Sbjct: 191 ACMGSPIPTGFIAYGVLHITNPSI---SLWKIFTIIIGGLTFIMTVVVILWFPNNPAD-V 246
Query: 329 SIFLTDDEIRLARKRLRENNTEKSDFHNKFFDKEVWKRIIFDWKIYVLTLWNIFCWNNNN 388
F + + + R R + S K F K ++ + D+ ++ L+ + NN
Sbjct: 247 KFFSIQERVWIIR---RVQASTGSSIEQKVFKKSQFREAMKDYITWLFGLFFLLQQLANN 303
Query: 389 GSSGAFLLWLNSLKNSDGSTRLSIEKKNQFSMITPGLGMVYLFLTSLLADKGHTRWGAI- 447
LL+ +G + S+ G +V F+ +L+ K W I
Sbjct: 304 LPYQQNLLF-------EGMGGVDALGSTLVSVAGAGFAVVCAFIATLMLAK----WKNIS 352
Query: 448 IVTQVF----NFIGNVILAA--WNVPEGAKWFAFML-QYFGWAMAPVLYSWQNDICRRDA 500
+T +F +G++ AA W+ G M Q FG + SW +
Sbjct: 353 ALTAIFWTLPALVGSIAAAALPWDNKIGILANICMAGQIFGIPFI-IALSWASS--SASG 409
Query: 501 QARAVILVVMNMLAQTSTAWISVLVWKTVEAPRYLKGFTWTAVAAFCLSAWTFVVLYFYK 560
+ + +++ A IS +W+ ++PR+L + V +F L+ ++++F
Sbjct: 410 YTKKLTRSSVSLFAMGIANIISPQIWREKDSPRFLPAWIVQIVLSFSLAPAILLLIHFIL 469
Query: 561 RDERRN 566
+ RRN
Sbjct: 470 K--RRN 473
>SPCPB1C11.03 [G] KOG2533 Permease of the major facilitator superfamily
Length = 570
Score = 60.8 bits (146), Expect = 5e-09
Identities = 83/393 (21%), Positives = 149/393 (37%), Gaps = 54/393 (13%)
Query: 150 YLDTVNLNNAYVSGMKEEIGFKGNDLVNTQVMYTVGNIIFQIPFIFILNKVPLNYVLPGL 209
++ L+ + + G+ +++ N N ++ VG I+ Q P +I+ PL + +
Sbjct: 114 FIGKATLSYSTILGLFDDVHITSNQYNNLNTLFYVGYIVGQFPGHYIMQTFPLGKFVGLV 173
Query: 210 DICWSLLTLGAAYVDTVPHLKAIRFFIGAFEAPSYLAYQYLFGCFYKHDEMVRRSAFYYF 269
WS++ L A+RFF+G E+ A + G F+ H E ++
Sbjct: 174 TFSWSVIVFLHCCAYNYGGLIALRFFLGFTESCLLPAMEATMGMFFTHQEQAFLQPVFWI 233
Query: 270 GQYAGVLSSGGIISAVHATMNGLHGKSGWRWNFIIDAVISVAVGLLGFYMLPGDPYNCYS 329
+ + +G I + + + W+ II I+ + + F+ P +P +
Sbjct: 234 SCLSCGIPAGFIAYGLEFVTKSI---APWKLFMIITGGITFFLSIFLFFYYPDNPSK--A 288
Query: 330 IFLTDDEIRLARKRLRENNTEKSDFHNKFFDKEVWKRIIFDWKIYVLTLWNIFCWNNNNG 389
FLTD+E R+R++ + NK F K + + D ++ T
Sbjct: 289 RFLTDEEKLYTIDRVRKST--RGGIENKIFKKHQFIEALKDPITWLFTF----------- 335
Query: 390 SSGAFLLWLNSLKNSDGSTRLSIEKKNQFSMITPGLGMVYLFLTSL-LADKGHTRWGAII 448
AF L L S L+ ++ ++I L + L T + +A G+ AII
Sbjct: 336 --AAFTLML--------SNNLAYQQ----NLIFTSLNVSDLNSTLVGVALAGYNTVSAII 381
Query: 449 VTQVFNFIGNVILAAWNVPEGAKWFA--FMLQYFGWAMAPVLYSWQNDICRRDAQARAVI 506
T A + +P + + A +ML +A V W N I
Sbjct: 382 AT----------FAMYLIPNQSAYHAMFWMLPSITGGIAFVALPWSNRIGE--------- 422
Query: 507 LVVMNMLAQTSTAWISVLVWKTVEAPRYLKGFT 539
L M + + +I L W T + Y K T
Sbjct: 423 LATMIIASDFGITYIIALGWTTATSTGYTKKLT 455
>SPAC1B3.15c [G] KOG2533 Permease of the major facilitator superfamily
Length = 628
Score = 50.8 bits (120), Expect = 6e-06
Identities = 42/156 (26%), Positives = 71/156 (44%), Gaps = 8/156 (5%)
Query: 176 VNTQVMYTVGNIIFQIPFIFILNKVPLNYVLPGLDICWSLLTLGAAYVDT----VPHLKA 231
V T + Y V IIF +P ++ + L + + ++ A + T A
Sbjct: 203 VGTGLSY-VSLIIFDLPSNLLMTRADPRLWLSRIQVTTGIIGACHAVLGTKGSSASGFIA 261
Query: 232 IRFFIGAFEAPSYLAYQYLFGCFYKHDEMVRRSAFYYFG-QYAGVLSSGGIISAVHATMN 290
+RFF G A + + + FY+ + +R +YY Q + V +S ++SA M+
Sbjct: 262 LRFFNGLAIAGMWPGFAFYTSRFYRDQHLGKRIGWYYTAAQISSVATS--LLSAAFQKMD 319
Query: 291 GLHGKSGWRWNFIIDAVISVAVGLLGFYMLPGDPYN 326
GLHG G++W F+I V++ GL LP +N
Sbjct: 320 GLHGLYGYQWMFLIWGVVAFTQGLFLPRWLPCIKHN 355
>SPAC1B3.16c [G] KOG2533 Permease of the major facilitator superfamily
Length = 568
Score = 50.4 bits (119), Expect = 7e-06
Identities = 39/162 (24%), Positives = 75/162 (46%), Gaps = 15/162 (9%)
Query: 169 GFKGNDLVNTQVMYTVGNIIFQIPFIFILNKVPLNYVLPGLDICWSLLTLGA-----AYV 223
G+ + L ++ VG IIF++P + + + ++ P + + LT+G A +
Sbjct: 123 GYSAHYLALGLALFYVGYIIFEVP-----SNLMMAFIEPRIWVSRIQLTIGVVGACHAVL 177
Query: 224 DT----VPHLKAIRFFIGAFEAPSYLAYQYLFGCFYKHDEMVRRSAFYYFGQYAGVLSSG 279
T A+RFF+G E+ + Y +Y+ + +R +YY ++
Sbjct: 178 GTKHGNAQSYVALRFFLGVAESGLWPGLAYYMSRWYRGKHLGKRIGWYYTAAQIAA-AAV 236
Query: 280 GIISAVHATMNGLHGKSGWRWNFIIDAVISVAVGLLGFYMLP 321
++SA M+G G G++W F+I V+++A L + LP
Sbjct: 237 SLVSAGFQKMDGARGLYGYQWMFLIWGVVAIAQALSIPWWLP 278
Database: KOG eukaryal database 04/03
Posted date: Apr 14, 2003 1:07 PM
Number of letters in database: 30,389,216
Number of sequences in database: 60,738
Lambda K H
0.322 0.137 0.440
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 35,903,487
Number of Sequences: 60738
Number of extensions: 1526333
Number of successful extensions: 3745
Number of sequences better than 1.0e-05: 20
Number of HSP's better than 0.0 without gapping: 9
Number of HSP's successfully gapped in prelim test: 11
Number of HSP's that attempted gapping in prelim test: 3701
Number of HSP's gapped (non-prelim): 23
length of query: 595
length of database: 30,389,216
effective HSP length: 112
effective length of query: 483
effective length of database: 23,586,560
effective search space: 11392308480
effective search space used: 11392308480
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.9 bits)