ORF STATUS Function Best COG Functional category Pathways and functional systems
r_klactIV3232 good E KOG2040 Amino acid transport and metabolism Glycine dehydrogenase (decarboxylating)
Only best alignment is shown:
BLASTP 2.2.3 [May-13-2002]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= r_klactIV3232 1090000 1086917 -1028
(1028 letters)
Database: KOG eukaryal database 04/03
60,738 sequences; 30,389,216 total letters
Searching..................................................done
Color Key for Alignment Scores: 
Score E
Sequences producing significant alignments: (bits) Value
YMR189w [E] KOG2040 Glycine dehydrogenase (decarboxylating) 1421 0.0
At2g26080 [E] KOG2040 Glycine dehydrogenase (decarboxylating) 974 0.0
SPAC13G6.06c [E] KOG2040 Glycine dehydrogenase (decarboxylating) 968 0.0
At4g33010 [E] KOG2040 Glycine dehydrogenase (decarboxylating) 968 0.0
Hs18573217 [E] KOG2040 Glycine dehydrogenase (decarboxylating) 961 0.0
Hs4504013 [E] KOG2040 Glycine dehydrogenase (decarboxylating) 959 0.0
7299318 [E] KOG2040 Glycine dehydrogenase (decarboxylating) 917 0.0
CE02846 [E] KOG2040 Glycine dehydrogenase (decarboxylating) 875 0.0
Hs20471026 [E] KOG2040 Glycine dehydrogenase (decarboxylating) 305 3e-82
>YMR189w [E] KOG2040 Glycine dehydrogenase (decarboxylating)
Length = 1034
Score = 1421 bits (3679), Expect = 0.0
Identities = 696/998 (69%), Positives = 831/998 (82%), Gaps = 14/998 (1%)
Query: 37 NVSSNQYGKIYEAKKNGPDAYEPLDTFQRRHLGPSPSNVDQMLKQLGYTDLDQFINGVVP 96
+++S QY +I+ D PLDTF RRHLGPSPS+V +MLK +GY+DL+ FI +VP
Sbjct: 43 DITSTQYSRIFNPDLKNID--RPLDTFARRHLGPSPSDVKKMLKTMGYSDLNAFIEELVP 100
Query: 97 ENILVKRPLELNSPENGFTEQQMLKHLEELANKNNHKVRNFIGKGYYGTVLPPVIQRNLL 156
NIL +RPL+L +P GF EQ+ML+HLE++ANKN++KV+NFIGKGYYGT+LPPVIQRNLL
Sbjct: 101 PNILKRRPLKLEAPSKGFCEQEMLQHLEKIANKNHYKVKNFIGKGYYGTILPPVIQRNLL 160
Query: 157 ECPEWYTSYTPYQPEISQGRLESLLNYQTVVSDLTGLPVANASLLDEGTAAGEAMLLSFN 216
E PEWYTSYTPYQPEISQGRLE+LLN+QTVVSDLTGLPVANASLLDEGTAAGEAMLLSFN
Sbjct: 161 ESPEWYTSYTPYQPEISQGRLEALLNFQTVVSDLTGLPVANASLLDEGTAAGEAMLLSFN 220
Query: 217 VAKKKKLTYVIDKRLHKQTKSVLKTRTEPFGIKLVEVDPLDESTWSVLSSDKDVSGCLVQ 276
+++KKKL YVIDK+LH+QTKSVL TR +PF I+++EVD D + + DVSGCLVQ
Sbjct: 221 ISRKKKLKYVIDKKLHQQTKSVLHTRAKPFNIEIIEVDCSDIKKAVDVLKNPDVSGCLVQ 280
Query: 277 YPDTEGNIIPGETLAKLADIVHQSKGLFAVASDLLALTLLKPPAQFGADIVLGSSQRFGV 336
YP T+G+I+P +++ +L+D +H K L +VASDL+ALTLLKPPA +GADIVLGSSQRFGV
Sbjct: 281 YPATDGSILPPDSMKQLSDALHSHKSLLSVASDLMALTLLKPPAHYGADIVLGSSQRFGV 340
Query: 337 PFGYGGPHAAFFSVIEKLNRKIPGRIVGVSKDRLGKPALRLALQTREQHIKRDKATSNIC 396
P GYGGPHAAFF+VI+KLNRKIPGRIVG+SKDRLGK ALRLALQTREQHIKRDKATSNIC
Sbjct: 341 PMGYGGPHAAFFAVIDKLNRKIPGRIVGISKDRLGKTALRLALQTREQHIKRDKATSNIC 400
Query: 397 TAQALLANIAANYCVYHGPQGLKEIAGRVYGFTTVLANGLSSSN--HTLLNKSWFDTLTV 454
TAQALLAN+A++YCVYHGP+GL+ I+ R++ T++LAN + + + H L+NK+WFDTLT+
Sbjct: 401 TAQALLANVASSYCVYHGPKGLQNISRRIFSLTSILANAIENDSCPHELINKTWFDTLTI 460
Query: 455 EL-NGISAQDFIKTAVDKYQINLYQVNNETVSLSLDETVTKDDLIALLELFGCNANELPV 513
+L NGIS++ + A+ ++ INL+ V+ T+SL+LDET TK D+ LL++F + +
Sbjct: 461 KLGNGISSEQLLDKALKEFNINLFAVDTTTISLALDETTTKADVENLLKVFDIENSSQFL 520
Query: 514 A---LPEFPQELTRQDEILSNEVFNTHHSETAMLRYLHRLQSRDLSLANSMIPLGSCTMK 570
+ FP+E R DEIL NEVF+ HHSETAMLRYLHRLQSRDLSLANSMIPLGSCTMK
Sbjct: 521 SEDYSNSFPREFQRTDEILRNEVFHMHHSETAMLRYLHRLQSRDLSLANSMIPLGSCTMK 580
Query: 571 LNATVEMIPITWPQFANIHPFQPRDQVEGYEVLIKNLEKDLASITGFDEVSLQPNSGAQG 630
LN+TVEM+PITWPQF+NIHPFQP +QV+GY+ LI +LEKDL SITGFD +SLQPNSGAQG
Sbjct: 581 LNSTVEMMPITWPQFSNIHPFQPSNQVQGYKELITSLEKDLCSITGFDGISLQPNSGAQG 640
Query: 631 EYAGLRVIRRYFEDRGETHRNICLIPVSAHGTNPASAAMCGLKVIPVNCLKNGSLDLVDL 690
EY GLRVIR Y E +GE HRN+CLIPVSAHGTNPASAAM GLKV+PVNCL++GSLDLVDL
Sbjct: 641 EYTGLRVIRSYLESKGENHRNVCLIPVSAHGTNPASAAMAGLKVVPVNCLQDGSLDLVDL 700
Query: 691 KAKAEKHKDNLAAIMITYPSTYGLFEPGVRTAIDLVHENGGQVYLDGANMNAQVGLTSPG 750
K KAE+H LAA+MITYPSTYGLFEPG++ AID+VH GGQVYLDGANMNAQVGLTSPG
Sbjct: 701 KNKAEQHSKELAAVMITYPSTYGLFEPGIQHAIDIVHSFGGQVYLDGANMNAQVGLTSPG 760
Query: 751 DLNADVCHLNLHKTFSIXXXXXXXXXXXICVQSHLAPYLPAHDVVPMITGVGSDKSIASV 810
DL ADVCHLNLHKTFSI ICV+SHL P+LP HDVV MITG+G KSI SV
Sbjct: 761 DLGADVCHLNLHKTFSIPHGGGGPAGAPICVKSHLIPHLPKHDVVDMITGIGGSKSIDSV 820
Query: 811 SSAPYGSASILPISYAYIKMMGSKGLPFSSVIAMLNANYMMSRLRPHYNILFVGEKGSTT 870
SSAPYG+A +LPISYAYIKMMG++GLPFSSVIAMLN+NYMM+RL+ HY ILFV E +
Sbjct: 821 SSAPYGNALVLPISYAYIKMMGNEGLPFSSVIAMLNSNYMMTRLKDHYKILFVNEMST-- 878
Query: 871 ETEDLTHCGHEFIIDLRAYKDQGVEAIDVAKRLQDYGFHAPTLAFPVPGTLMVXXXXXXX 930
L HC HEFI+DLR YK +GVEAIDVAKRLQDYGFHAPTLAFPVPGTLM+
Sbjct: 879 ----LKHCAHEFIVDLREYKAKGVEAIDVAKRLQDYGFHAPTLAFPVPGTLMIEPTESEN 934
Query: 931 XXXXXRFIDAMISIKKEIDLFIKGDPQGQVLKNSPHSLEDVVSSDDWSSRGYTREQAVYP 990
RF DAMISIK+EI+ + G P+GQ+LKN+PHSLED+++S +W +RGYTRE+A YP
Sbjct: 935 LEELDRFCDAMISIKEEINALVAGQPKGQILKNAPHSLEDLITSSNWDTRGYTREEAAYP 994
Query: 991 LPYLKYNKFWPPVARLDDTYGDTHLMCTCPSVEEVASE 1028
LP+L+YNKFWP VARLDDTYGD +L+CTCPSVEE+A+E
Sbjct: 995 LPFLRYNKFWPTVARLDDTYGDMNLICTCPSVEEIANE 1032
>At2g26080 [E] KOG2040 Glycine dehydrogenase (decarboxylating)
Length = 1044
Score = 974 bits (2519), Expect = 0.0
Identities = 519/998 (52%), Positives = 672/998 (67%), Gaps = 43/998 (4%)
Query: 47 YEAKKNGPDAYEPLDTFQRRHLGPSPSNVDQMLKQLGYTDLDQFINGVVPENILVKRPLE 106
++ + DA +P DTF RRH +P QM G+ +L+ I+ VP++I +
Sbjct: 68 HQTRSISVDALKPSDTFPRRHNSATPDEQAQMANYCGFDNLNTLIDSTVPKSIRLDSMKF 127
Query: 107 LNSPENGFTEQQMLKHLEELANKNNHKVRNFIGKGYYGTVLPPVIQRNLLECPEWYTSYT 166
+ G TE QM++H+ +LA+KN ++FIG GYY T +PPVI RN++E P WYT YT
Sbjct: 128 SGIFDEGLTESQMIEHMSDLASKNK-VFKSFIGMGYYNTHVPPVILRNIMENPAWYTQYT 186
Query: 167 PYQPEISQGRLESLLNYQTVVSDLTGLPVANASLLDEGTAAGEAMLLSFNVAKKKKLTYV 226
PYQ EISQGRLESLLNYQTV++DLTGLP++NASLLDEGTAA EAM + N+ K KK T+V
Sbjct: 187 PYQAEISQGRLESLLNYQTVITDLTGLPMSNASLLDEGTAAAEAMAMCNNILKGKKKTFV 246
Query: 227 IDKRLHKQTKSVLKTRTEPFGIKLVEVDPLDESTWSVLSSDKDVSGCLVQYPDTEGNIIP 286
I H QT V KTR + F +K+V VD D V S DV G LVQYP TEG ++
Sbjct: 247 IASNCHPQTIDVCKTRADGFDLKVVTVDIKD-----VDYSSGDVCGVLVQYPGTEGEVLD 301
Query: 287 GETLAKLADIVHQSKGLFAVASDLLALTLLKPPAQFGADIVLGSSQRFGVPFGYGGPHAA 346
K A H + +A+DLLALT+LKPP +FGADIV+GS QRFGVP GYGGPHAA
Sbjct: 302 YGEFVKNA---HANGVKVVMATDLLALTMLKPPGEFGADIVVGSGQRFGVPMGYGGPHAA 358
Query: 347 FFSVIEKLNRKIPGRIVGVSKDRLGKPALRLALQTREQHIKRDKATSNICTAQALLANIA 406
F + ++ R +PGRI+GVS D GK ALR+A+QTREQHI+RDKATSNICTAQALLAN+
Sbjct: 359 FLATSQEYKRMMPGRIIGVSVDSSGKQALRMAMQTREQHIRRDKATSNICTAQALLANMT 418
Query: 407 ANYCVYHGPQGLKEIAGRVYGFTTVLANGLSS-SNHTLLNKSWFDTLTVELNGISAQDFI 465
A Y VYHGP+GLK IA RV+G V A GL + + +FDT+ V + +A I
Sbjct: 419 AMYAVYHGPEGLKSIAQRVHGLAGVFALGLKKLGTAQVQDLPFFDTVKVTCSDATA---I 475
Query: 466 KTAVDKYQINLYQVNNETVSLSLDETVTKDDLIALLELFGCNANELPVAL------PEF- 518
K +INL V++ T++++ DET T DD+ L E+F A+ PV PEF
Sbjct: 476 FDVAAKKEINLRLVDSNTITVAFDETTTLDDVDKLFEVF---ASGKPVQFTAESLAPEFN 532
Query: 519 ---PQELTRQDEILSNEVFNTHHSETAMLRYLHRLQSRDLSLANSMIPLGSCTMKLNATV 575
P LTR+ L++ +FN +H+E +LRY+H+LQ++DLSL +SMIPLGSCTMKLNAT
Sbjct: 533 NAIPSSLTRESPYLTHPIFNMYHTEHELLRYIHKLQNKDLSLCHSMIPLGSCTMKLNATT 592
Query: 576 EMIPITWPQFANIHPFQPRDQVEGYEVLIKNLEKDLASITGFDEVSLQPNSGAQGEYAGL 635
EM+P+TWP F N+HPF P +Q +GY+ + NL + L +ITGFD SLQPN+GA GEYAGL
Sbjct: 593 EMMPVTWPSFTNMHPFAPVEQAQGYQEMFTNLGELLCTITGFDSFSLQPNAGAAGEYAGL 652
Query: 636 RVIRRYFEDRGETHRNICLIPVSAHGTNPASAAMCGLKVIPVNCLKNGSLDLVDLKAKAE 695
VIR Y RG+ HRN+C+IPVSAHGTNPASAAMCG+K++ V G++++ +L+ AE
Sbjct: 653 MVIRAYHMSRGDHHRNVCIIPVSAHGTNPASAAMCGMKIVAVGTDAKGNINIEELRNAAE 712
Query: 696 KHKDNLAAIMITYPSTYGLFEPGVRTAIDLVHENGGQVYLDGANMNAQVGLTSPGDLNAD 755
+KDNLAA+M+TYPST+G++E G+ +++HENGGQVY+DGANMNAQVGLTSPG + AD
Sbjct: 713 ANKDNLAALMVTYPSTHGVYEEGIDEICNIIHENGGQVYMDGANMNAQVGLTSPGFIGAD 772
Query: 756 VCHLNLHKTFSIXXXXXXXXXXXICVQSHLAPYLPAHDVVPM--ITGVGSDKSIASVSSA 813
VCHLNLHKTF I I V+ HLAP+LP+H V+P I + ++S+A
Sbjct: 773 VCHLNLHKTFCIPHGGGGPGMGPIGVKQHLAPFLPSHPVIPTGGIPEPEQTSPLGTISAA 832
Query: 814 PYGSASILPISYAYIKMMGSKGLPFSSVIAMLNANYMMSRLRPHYNILFVGEKGSTTETE 873
P+GSA ILPISY YI MMGS GL +S IA+LNANYM RL HY +LF G G+
Sbjct: 833 PWGSALILPISYTYIAMMGSGGLTDASKIAILNANYMAKRLESHYPVLFRGVNGTV---- 888
Query: 874 DLTHCGHEFIIDLRAYKD-QGVEAIDVAKRLQDYGFHAPTLAFPVPGTLMVXXXXXXXXX 932
HEFIIDLR +K+ G+E DVAKRL DYGFH PT+++PVPGTLM+
Sbjct: 889 -----AHEFIIDLRGFKNTAGIEPEDVAKRLMDYGFHGPTMSWPVPGTLMIEPTESESKA 943
Query: 933 XXXRFIDAMISIKKEIDLFIKG--DPQGQVLKNSPHSLEDVVSSDDWSSRGYTREQAVYP 990
RF DA+ISI++EI KG DP VLK +PH ++ +D W + Y+RE A +P
Sbjct: 944 ELDRFCDALISIREEISQIEKGNADPNNNVLKGAPHP-PSLLMADTW-KKPYSREYAAFP 1001
Query: 991 LPYLKYNKFWPPVARLDDTYGDTHLMCTC-PSVEEVAS 1027
P+L+ +KFWP R+D+ YGD +L+CT P+ EE A+
Sbjct: 1002 APWLRSSKFWPTTGRVDNVYGDRNLVCTLQPANEEQAA 1039
>SPAC13G6.06c [E] KOG2040 Glycine dehydrogenase (decarboxylating)
Length = 1017
Score = 968 bits (2502), Expect = 0.0
Identities = 524/1035 (50%), Positives = 676/1035 (64%), Gaps = 64/1035 (6%)
Query: 22 GLTPALGYRFVSTKCNVSSNQYGKIYEAKKNGPDAYEPLDTFQRRHLGPSPSNVDQMLKQ 81
G+ +L K N+S + EAK + + LDTF+ RH+GPS ++ L+
Sbjct: 12 GVNTSLSRHLFLAKRNLSISS--ACLEAKNS--QKFPALDTFEPRHIGPSKTDQQYQLES 67
Query: 82 LGYTDLDQFINGVVPENILVKR----------PLELNSPENGFTEQQMLKHLEELANKNN 131
LGY D D F+ V+P+++ P E N P N ++E + +AN+N
Sbjct: 68 LGYKDFDSFLKDVIPDSVRTPESQLMAFGSVNPNEKNPPVN-YSESEFTTLANNVANQNK 126
Query: 132 HKVRNFIGKGYYGTVLPPVIQRNLLECPEWYTSYTPYQPEISQGRLESLLNYQTVVSDLT 191
+++FIG GYY LP IQRN+LE PEWYT YTPYQ EISQGRLES++NYQT+++DLT
Sbjct: 127 -LIKSFIGMGYYNVKLPAAIQRNVLENPEWYTQYTPYQAEISQGRLESMMNYQTMIADLT 185
Query: 192 GLPVANASLLDEGTAAGEAMLLSFNVAKKKKLTYVIDKRLHKQTKSVLKTRTEPFGIKLV 251
GL ++NASLLDEGTAAGEAM++ KKK+ T+++DK ++ T SVL+TR FGIK +
Sbjct: 186 GLSISNASLLDEGTAAGEAMVMLMANDKKKRKTFLVDKNIYPNTLSVLRTRASGFGIK-I 244
Query: 252 EVDPLDESTWSVLSSDKDVSGCLVQYPDTEGNIIPGETLAKLADIVHQSKGLFAVASDLL 311
E+D + + S K V G VQYP +G+I LA A + A+DLL
Sbjct: 245 ELDNITPEL--ITKSAKHVFGIFVQYPAADGSIFDYGHLAATARSFNMH---VVAATDLL 299
Query: 312 ALTLLKPPAQFGADIVLGSSQRFGVPFGYGGPHAAFFSVIEKLNRKIPGRIVGVSKDRLG 371
ALT+LK P ++GAD+ +GS+QRFG+P GYGGPHA FF+ E+ RKIPGR++G+SKDRL
Sbjct: 300 ALTILKSPGEWGADVAVGSTQRFGLPMGYGGPHAGFFACSEEFKRKIPGRLIGLSKDRLE 359
Query: 372 KPALRLALQTREQHIKRDKATSNICTAQALLANIAANYCVYHGPQGLKEIAGRVYGFTTV 431
PA RLALQTREQHI+R+KATSNICTAQALLAN++A Y +YHGP GL+EIA R+Y T+
Sbjct: 360 NPAYRLALQTREQHIRREKATSNICTAQALLANMSAFYAIYHGPNGLQEIANRIYASTSF 419
Query: 432 LANGLSSSNHTLLNKS-WFDTLTVELNGISAQDFIKTAVDKYQINLYQVNNETVSLSLDE 490
L + L SS + ++NKS +FDTLT+E+ SA + A+D + NL +V++ V LSLDE
Sbjct: 420 LKSALESSGYKIVNKSHFFDTLTIEVE--SADKVLAKALD-HGYNLRKVDDSHVGLSLDE 476
Query: 491 TVTKDDLIALLELFGCNAN------ELPVALPE--------------FPQELTRQDEILS 530
TV D+ AL +F N + E+ + P P+ R L
Sbjct: 477 TVCDKDIQALFSIFNINKSVDQYYMEIATSEPNGNSASTVDNLSICSLPENFRRTTLYLQ 536
Query: 531 NEVFNTHHSETAMLRYLHRLQSRDLSLANSMIPLGSCTMKLNATVEMIPITWPQFANIHP 590
+ VFN +HSET ++RY+H LQS+DLSLA++M PLGSCTMKLNA EM+PIT P FANIHP
Sbjct: 537 HPVFNRYHSETELMRYIHHLQSKDLSLAHAMTPLGSCTMKLNAVTEMMPITNPLFANIHP 596
Query: 591 FQPRDQVEGYEVLIKNLEKDLASITGFDEVSLQPNSGAQGEYAGLRVIRRYFEDRGETHR 650
+ P +Q +GY +I++L+ L +ITGFD QPNSGA GEY GL VIR Y G+ HR
Sbjct: 597 YVPEEQAKGYRHVIEDLQLMLTTITGFDAACFQPNSGAAGEYTGLSVIRAYQRSIGQGHR 656
Query: 651 NICLIPVSAHGTNPASAAMCGLKVIPVNCLKNGSLDLVDLKAKAEKHKDNLAAIMITYPS 710
NICLIPVSAHGTNPASAAM G VIPV CL NG LD+ DLK KA KH D LAA M+TYPS
Sbjct: 657 NICLIPVSAHGTNPASAAMAGFTVIPVKCLNNGYLDMQDLKEKASKHADKLAAFMVTYPS 716
Query: 711 TYGLFEPGVRTAIDLVHENGGQVYLDGANMNAQVGLTSPGDLNADVCHLNLHKTFSIXXX 770
T+G+FEP V+ A++++HE+GGQVY DGANMNA VGL GD+ ADVCHLNLHKTF I
Sbjct: 717 TFGIFEPDVKEALEVIHEHGGQVYFDGANMNAMVGLCKAGDIGADVCHLNLHKTFCIPHG 776
Query: 771 XXXXXXXXICVQSHLAPYLPAHDVVPMITGVGSDKSIASVSSAPYGSASILPISYAYIKM 830
ICV+ HLA +LP+H VV G I SVSS+P+GSA ILPIS+AY++M
Sbjct: 777 GGGPGVGPICVKKHLADFLPSHPVV----SCGGKNGITSVSSSPFGSAGILPISWAYMRM 832
Query: 831 MGSKGLPFSSVIAMLNANYMMSRLRPHYNILFVGEKGSTTETEDLTHCGHEFIIDLRAYK 890
MG GL +S A+LNANYM RL HY +++ + C HEFI+D R +K
Sbjct: 833 MGLAGLRDASKAALLNANYMAKRLSSHYKLVYTNKNNL---------CAHEFILDAREFK 883
Query: 891 -DQGVEAIDVAKRLQDYGFHAPTLAFPVPGTLMVXXXXXXXXXXXXRFIDAMISIKKEID 949
GV+A D+AKRLQDY FHAPTL++P+ TLM+ RF DA+ISI++EI
Sbjct: 884 ATAGVDATDIAKRLQDYSFHAPTLSWPIANTLMIEPTESESMYEMDRFCDALISIRQEIR 943
Query: 950 LFIKG--DPQGQVLKNSPHSLEDVVSSDDWSSRGYTREQAVYPLPYLKYNKFWPPVARLD 1007
+G +L N+PH +D ++S+ W R YTRE+AVYP+P LK KFWP VARLD
Sbjct: 944 EIEEGLQPKDNNLLVNAPHPQKD-IASEKW-DRPYTRERAVYPVPLLKERKFWPSVARLD 1001
Query: 1008 DTYGDTHLMCTCPSV 1022
D YGD +L CTC V
Sbjct: 1002 DAYGDKNLFCTCSPV 1016
>At4g33010 [E] KOG2040 Glycine dehydrogenase (decarboxylating)
Length = 1037
Score = 968 bits (2502), Expect = 0.0
Identities = 516/1012 (50%), Positives = 679/1012 (66%), Gaps = 39/1012 (3%)
Query: 31 FVSTKCNVSSNQ-YGKIYEAKKNGPDAYEPLDTFQRRHLGPSPSNVDQMLKQLGYTDLDQ 89
F+ST +V+ +G+ + + DA +P DTF RRH +P M K G+ +D
Sbjct: 46 FISTPRSVNHTAAFGRHQQTRSISVDAVKPSDTFPRRHNSATPDEQTHMAKFCGFDHIDS 105
Query: 90 FINGVVPENILVKRPLELNSPENGFTEQQMLKHLEELANKNNHKVRNFIGKGYYGTVLPP 149
I+ VP++I + ++ + + G TE QM++H+ +LA+KN ++FIG GYY T +P
Sbjct: 106 LIDATVPKSIRLDS-MKFSKFDAGLTESQMIQHMVDLASKNK-VFKSFIGMGYYNTHVPT 163
Query: 150 VIQRNLLECPEWYTSYTPYQPEISQGRLESLLNYQTVVSDLTGLPVANASLLDEGTAAGE 209
VI RN++E P WYT YTPYQ EISQGRLESLLN+QTV++DLTGLP++NASLLDEGTAA E
Sbjct: 164 VILRNIMENPAWYTQYTPYQAEISQGRLESLLNFQTVITDLTGLPMSNASLLDEGTAAAE 223
Query: 210 AMLLSFNVAKKKKLTYVIDKRLHKQTKSVLKTRTEPFGIKLVEVDPLDESTWSVLSSDKD 269
AM + N+ K KK T+VI H QT V KTR + F +K+V D D + S D
Sbjct: 224 AMAMCNNILKGKKKTFVIASNCHPQTIDVCKTRADGFDLKVVTSDLKD-----IDYSSGD 278
Query: 270 VSGCLVQYPDTEGNIIPGETLAKLADIVHQSKGLFAVASDLLALTLLKPPAQFGADIVLG 329
V G LVQYP TEG ++ K A H + +A+DLLALT+LKPP +FGADIV+G
Sbjct: 279 VCGVLVQYPGTEGEVLDYAEFVKNA---HANGVKVVMATDLLALTVLKPPGEFGADIVVG 335
Query: 330 SSQRFGVPFGYGGPHAAFFSVIEKLNRKIPGRIVGVSKDRLGKPALRLALQTREQHIKRD 389
S+QRFGVP GYGGPHAAF + ++ R +PGRI+G+S D GK ALR+A+QTREQHI+RD
Sbjct: 336 SAQRFGVPMGYGGPHAAFLATSQEYKRMMPGRIIGISVDSSGKQALRMAMQTREQHIRRD 395
Query: 390 KATSNICTAQALLANIAANYCVYHGPQGLKEIAGRVYGFTTVLANGLSSSNHTLLNK-SW 448
KATSNICTAQALLAN+AA Y VYHGP GLK IA RV+G + + GL+ + + +
Sbjct: 396 KATSNICTAQALLANMAAMYAVYHGPAGLKSIAQRVHGLAGIFSLGLNKLGVAEVQELPF 455
Query: 449 FDTLTVELNGISAQDFIKTAVDKYQINLYQVNNETVSLSLDETVTKDDLIALLELFGCN- 507
FDT+ ++ + A I A K +INL V++ T++ S DET T DD+ L ++F
Sbjct: 456 FDTVKIKCSDAHA---IADAASKSEINLRVVDSTTITASFDETTTLDDVDKLFKVFASGK 512
Query: 508 -----ANEL-PVALPEFPQELTRQDEILSNEVFNTHHSETAMLRYLHRLQSRDLSLANSM 561
A L P P LTR+ L++ +FN +H+E +LRY+H+LQS+DLSL +SM
Sbjct: 513 PVPFTAESLAPEVQNSIPSSLTRESPYLTHPIFNMYHTEHELLRYIHKLQSKDLSLCHSM 572
Query: 562 IPLGSCTMKLNATVEMIPITWPQFANIHPFQPRDQVEGYEVLIKNLEKDLASITGFDEVS 621
IPLGSCTMKLNAT EM+P+TWP F +IHPF P +Q +GY+ + +NL L +ITGFD S
Sbjct: 573 IPLGSCTMKLNATTEMMPVTWPSFTDIHPFAPVEQAQGYQEMFENLGDLLCTITGFDSFS 632
Query: 622 LQPNSGAQGEYAGLRVIRRYFEDRGETHRNICLIPVSAHGTNPASAAMCGLKVIPVNCLK 681
LQPN+GA GEYAGL VIR Y RG+ HRN+C+IPVSAHGTNPASAAMCG+K+I V
Sbjct: 633 LQPNAGAAGEYAGLMVIRAYHMSRGDHHRNVCIIPVSAHGTNPASAAMCGMKIITVGTDA 692
Query: 682 NGSLDLVDLKAKAEKHKDNLAAIMITYPSTYGLFEPGVRTAIDLVHENGGQVYLDGANMN 741
G++++ +++ AE +KDNLAA+M+TYPST+G++E G+ +++HENGGQVY+DGANMN
Sbjct: 693 KGNINIEEVRKAAEANKDNLAALMVTYPSTHGVYEEGIDEICNIIHENGGQVYMDGANMN 752
Query: 742 AQVGLTSPGDLNADVCHLNLHKTFSIXXXXXXXXXXXICVQSHLAPYLPAHDVVPM--IT 799
AQVGLTSPG + ADVCHLNLHKTF I I V++HLAP+LP+H V+P I
Sbjct: 753 AQVGLTSPGFIGADVCHLNLHKTFCIPHGGGGPGMGPIGVKNHLAPFLPSHPVIPTGGIP 812
Query: 800 GVGSDKSIASVSSAPYGSASILPISYAYIKMMGSKGLPFSSVIAMLNANYMMSRLRPHYN 859
+ ++S+AP+GSA ILPISY YI MMGS GL +S IA+LNANYM RL HY
Sbjct: 813 QPEKTAPLGAISAAPWGSALILPISYTYIAMMGSGGLTDASKIAILNANYMAKRLEKHYP 872
Query: 860 ILFVGEKGSTTETEDLTHCGHEFIIDLRAYKD-QGVEAIDVAKRLQDYGFHAPTLAFPVP 918
+LF G G+ HEFIIDLR +K+ G+E DVAKRL DYGFH PT+++PVP
Sbjct: 873 VLFRGVNGTV---------AHEFIIDLRGFKNTAGIEPEDVAKRLMDYGFHGPTMSWPVP 923
Query: 919 GTLMVXXXXXXXXXXXXRFIDAMISIKKEIDLFIKG--DPQGQVLKNSPHSLEDVVSSDD 976
GTLM+ RF DA+ISI++EI KG D Q VLK +PH ++ +D
Sbjct: 924 GTLMIEPTESESKAELDRFCDALISIREEIAQIEKGNADVQNNVLKGAPHP-PSLLMADT 982
Query: 977 WSSRGYTREQAVYPLPYLKYNKFWPPVARLDDTYGDTHLMCT-CPSVEEVAS 1027
W + Y+RE A +P P+L+ +KFWP R+D+ YGD L+CT P E+VA+
Sbjct: 983 W-KKPYSREYAAFPAPWLRSSKFWPTTGRVDNVYGDRKLVCTLLPEEEQVAA 1033
>Hs18573217 [E] KOG2040 Glycine dehydrogenase (decarboxylating)
Length = 1020
Score = 961 bits (2484), Expect = 0.0
Identities = 518/975 (53%), Positives = 664/975 (67%), Gaps = 41/975 (4%)
Query: 61 DTFQRRHLGPSPSNVDQMLKQLGYTDLDQFINGVVPENILVKRPLELNSPENGFTEQQML 120
D F RRH+GP + +ML+ LG +D+ I VP NI +KRPL++ P E ++L
Sbjct: 61 DDFARRHIGPGDKDQREMLQTLGLASIDELIEKTVPANIRLKRPLKMEDP---VCENEIL 117
Query: 121 KHLEELANKNNHKVRNFIGKGYYGTVLPPVIQRNLLECPEWYTSYTPYQPEISQGRLESL 180
L +++KN R++IG GYY +P I RNLLE W T YTPYQPE+SQGRLESL
Sbjct: 118 ATLHAISSKNQIW-RSYIGMGYYNCSVPQTILRNLLENSGWITQYTPYQPEVSQGRLESL 176
Query: 181 LNYQTVVSDLTGLPVANASLLDEGTAAGEAMLLSFNVAKKKKLTYVIDKRLHKQTKSVLK 240
LNYQT+V D+TGL +ANASLLDEGTAA EA+ L + K++K +++D R H QT +V++
Sbjct: 177 LNYQTMVCDITGLDMANASLLDEGTAAAEALQLCYRHNKRRK--FLVDPRCHPQTIAVVQ 234
Query: 241 TRTEPFGIKLVEVDPLDESTWSVLSSDKDVSGCLVQYPDTEGNIIPGETLAKLADIVHQS 300
TR + G+ L E+ E +S KDVSG L QYPDTEG + E +L + HQS
Sbjct: 235 TRAKYTGV-LTELKLPCEMDFS----GKDVSGVLFQYPDTEGKV---EDFTELVERAHQS 286
Query: 301 KGLFAVASDLLALTLLKPPAQFGADIVLGSSQRFGVPFGYGGPHAAFFSVIEKLNRKIPG 360
L A+DLLAL +L+PP +FG DI LGSSQRFGVP GYGGPHAAFF+V E L R +PG
Sbjct: 287 GSLACCATDLLALCILRPPGEFGVDIALGSSQRFGVPLGYGGPHAAFFAVRESLVRMMPG 346
Query: 361 RIVGVSKDRLGKPALRLALQTREQHIKRDKATSNICTAQALLANIAANYCVYHGPQGLKE 420
R+VGV++D GK RLALQTREQHI+RDKATSNICTAQALLAN+AA + +YHG GL+
Sbjct: 347 RMVGVTRDATGKEVYRLALQTREQHIRRDKATSNICTAQALLANMAAMFAIYHGSHGLEH 406
Query: 421 IAGRVYGFTTVLANGLSSSNHTLLNKSWFDTLTVELNGISAQDFIKTAVDKYQINLYQVN 480
IA RV+ T +L+ GL + H L + +FDTL ++ G S ++ + A + QIN
Sbjct: 407 IARRVHNATLILSEGLKRAGHQLQHDLFFDTLKIQC-GCSVKEVLGRAAQR-QINFRLFE 464
Query: 481 NETVSLSLDETVTKDDLIALLELFGCNANELPVALPEFPQE--------LTRQDEILSNE 532
+ T+ +SLDETV + DL LL +FGC ++ VA +E R L+++
Sbjct: 465 DGTLGISLDETVNEKDLDDLLWIFGCESSAELVA-ESMGEECRGIPGSVFKRTSPFLTHQ 523
Query: 533 VFNTHHSETAMLRYLHRLQSRDLSLANSMIPLGSCTMKLNATVEMIPITWPQFANIHPFQ 592
VFN++HSET ++RY+ +L+++D+SL +SMIPLGSCTMKLN++ E+ PITW +FANIHPF
Sbjct: 524 VFNSYHSETNIVRYMKKLENKDISLVHSMIPLGSCTMKLNSSSELAPITWKEFANIHPFV 583
Query: 593 PRDQVEGYEVLIKNLEKDLASITGFDEVSLQPNSGAQGEYAGLRVIRRYFEDRGETHRNI 652
P DQ +GY+ L + LEKDL +TG+D+V QPNSGAQGEYAGL IR Y +GE HR +
Sbjct: 584 PLDQAQGYQQLFRELEKDLCELTGYDQVCFQPNSGAQGEYAGLATIRAYLNQKGEGHRTV 643
Query: 653 CLIPVSAHGTNPASAAMCGLKVIPVNCLKNGSLDLVDLKAKAEKHKDNLAAIMITYPSTY 712
CLIP SAHGTNPASA M G+K+ PV K G++D V LKA +KHK+NLAAIMITYPST
Sbjct: 644 CLIPKSAHGTNPASAHMAGMKIQPVEVDKYGNIDAVHLKAMVDKHKENLAAIMITYPSTN 703
Query: 713 GLFEPGVRTAIDLVHENGGQVYLDGANMNAQVGLTSPGDLNADVCHLNLHKTFSIXXXXX 772
G+FE + DL+H++GGQVYLDGANMNAQVG+ PGD +DV HLNLHKTF I
Sbjct: 704 GVFEENISDVCDLIHQHGGQVYLDGANMNAQVGICRPGDFGSDVSHLNLHKTFCIPHGGG 763
Query: 773 XXXXXXICVQSHLAPYLPAHDVVPMITGVGSDKSIASVSSAPYGSASILPISYAYIKMMG 832
I V+ HLAP+LP H V+ + + + +VS+AP+GS+SILPIS+AYIKMMG
Sbjct: 764 GPGMGPIGVKKHLAPFLPNHPVISLKRNEDA-CPVGTVSAAPWGSSSILPISWAYIKMMG 822
Query: 833 SKGLPFSSVIAMLNANYMMSRLRPHYNILFVGEKGSTTETEDLTHCGHEFIIDLRAY-KD 891
KGL ++ A+LNANYM RL HY ILF G +G + GHEFI+D R + K
Sbjct: 823 GKGLKQATETAILNANYMAKRLETHYRILFRGARG---------YVGHEFILDTRPFKKS 873
Query: 892 QGVEAIDVAKRLQDYGFHAPTLAFPVPGTLMVXXXXXXXXXXXXRFIDAMISIKKEIDLF 951
+EA+DVAKRLQDYGFHAPT+++PV GTLMV RF DAMISI++EI
Sbjct: 874 ANIEAVDVAKRLQDYGFHAPTMSWPVAGTLMVEPTESEDKAELDRFCDAMISIRQEIADI 933
Query: 952 IKG--DPQGQVLKNSPHSLEDVVSSDDWSSRGYTREQAVYPLPYLK-YNKFWPPVARLDD 1008
+G DP+ LK SPHSL V SS W R Y+RE A +PLP++K NKFWP +AR+DD
Sbjct: 934 EEGRIDPRVNPLKMSPHSLTCVTSS-HW-DRPYSREVAAFPLPFVKPENKFWPTIARIDD 991
Query: 1009 TYGDTHLMCTCPSVE 1023
YGD HL+CTCP +E
Sbjct: 992 IYGDQHLVCTCPPME 1006
>Hs4504013 [E] KOG2040 Glycine dehydrogenase (decarboxylating)
Length = 1020
Score = 959 bits (2480), Expect = 0.0
Identities = 518/975 (53%), Positives = 663/975 (67%), Gaps = 41/975 (4%)
Query: 61 DTFQRRHLGPSPSNVDQMLKQLGYTDLDQFINGVVPENILVKRPLELNSPENGFTEQQML 120
D F RRH+GP + +ML+ LG +D+ I VP NI +KRPL++ P E ++L
Sbjct: 61 DDFARRHIGPGDKDQREMLQTLGLASIDELIEKTVPANIRLKRPLKMEDP---VCENEIL 117
Query: 121 KHLEELANKNNHKVRNFIGKGYYGTVLPPVIQRNLLECPEWYTSYTPYQPEISQGRLESL 180
L +++KN R++IG GYY +P I RNLLE W T YTPYQPE+SQGRLESL
Sbjct: 118 ATLHAISSKNQIW-RSYIGMGYYNCSVPQTILRNLLENSGWITQYTPYQPEVSQGRLESL 176
Query: 181 LNYQTVVSDLTGLPVANASLLDEGTAAGEAMLLSFNVAKKKKLTYVIDKRLHKQTKSVLK 240
LNYQT+V D+TGL +ANASLLDEGTAA EA+ L + K++K +++D R H QT +V++
Sbjct: 177 LNYQTMVCDITGLDMANASLLDEGTAAAEALQLCYRHNKRRK--FLVDPRCHPQTIAVVQ 234
Query: 241 TRTEPFGIKLVEVDPLDESTWSVLSSDKDVSGCLVQYPDTEGNIIPGETLAKLADIVHQS 300
TR + G+ L E+ E +S KDVSG L QYPDTEG + E +L + HQS
Sbjct: 235 TRAKYTGV-LTELKLPCEMDFS----GKDVSGVLFQYPDTEGKV---EDFTELVERAHQS 286
Query: 301 KGLFAVASDLLALTLLKPPAQFGADIVLGSSQRFGVPFGYGGPHAAFFSVIEKLNRKIPG 360
L A+DLLAL +L+PP +FG DI LGSSQRFGVP GYGGPHAAFF+V E L R +PG
Sbjct: 287 GSLACCATDLLALCILRPPGEFGVDIALGSSQRFGVPLGYGGPHAAFFAVRESLVRMMPG 346
Query: 361 RIVGVSKDRLGKPALRLALQTREQHIKRDKATSNICTAQALLANIAANYCVYHGPQGLKE 420
R+VGV++D GK RLALQTREQHI+RDKATSNICTAQALLAN+AA + +YHG GL+
Sbjct: 347 RMVGVTRDATGKEVYRLALQTREQHIRRDKATSNICTAQALLANMAAMFRIYHGSHGLEH 406
Query: 421 IAGRVYGFTTVLANGLSSSNHTLLNKSWFDTLTVELNGISAQDFIKTAVDKYQINLYQVN 480
IA RV+ T +L+ GL + H L + +FDTL + G S ++ + A + QIN
Sbjct: 407 IARRVHNATLILSEGLKRAGHQLQHDLFFDTLKIHC-GCSVKEVLGRAAQR-QINFRLFE 464
Query: 481 NETVSLSLDETVTKDDLIALLELFGCNANELPVALPEFPQE--------LTRQDEILSNE 532
+ T+ +SLDETV + DL LL +FGC ++ VA +E R L+++
Sbjct: 465 DGTLGISLDETVNEKDLDDLLWIFGCESSAELVA-ESMGEECRGIPGSVFKRTSPFLTHQ 523
Query: 533 VFNTHHSETAMLRYLHRLQSRDLSLANSMIPLGSCTMKLNATVEMIPITWPQFANIHPFQ 592
VFN++HSET ++RY+ +L+++D+SL +SMIPLGSCTMKLN++ E+ PITW +FANIHPF
Sbjct: 524 VFNSYHSETNIVRYMKKLENKDISLVHSMIPLGSCTMKLNSSSELAPITWKEFANIHPFV 583
Query: 593 PRDQVEGYEVLIKNLEKDLASITGFDEVSLQPNSGAQGEYAGLRVIRRYFEDRGETHRNI 652
P DQ +GY+ L + LEKDL +TG+D+V QPNSGAQGEYAGL IR Y +GE HR +
Sbjct: 584 PLDQAQGYQQLFRELEKDLCELTGYDQVCFQPNSGAQGEYAGLATIRAYLNQKGEGHRTV 643
Query: 653 CLIPVSAHGTNPASAAMCGLKVIPVNCLKNGSLDLVDLKAKAEKHKDNLAAIMITYPSTY 712
CLIP SAHGTNPASA M G+K+ PV K G++D V LKA +KHK+NLAAIMITYPST
Sbjct: 644 CLIPKSAHGTNPASAHMAGMKIQPVEVDKYGNIDAVHLKAMVDKHKENLAAIMITYPSTN 703
Query: 713 GLFEPGVRTAIDLVHENGGQVYLDGANMNAQVGLTSPGDLNADVCHLNLHKTFSIXXXXX 772
G+FE + DL+H++GGQVYLDGANMNAQVG+ PGD +DV HLNLHKTF I
Sbjct: 704 GVFEENISDVCDLIHQHGGQVYLDGANMNAQVGICRPGDFGSDVSHLNLHKTFCIPHGGG 763
Query: 773 XXXXXXICVQSHLAPYLPAHDVVPMITGVGSDKSIASVSSAPYGSASILPISYAYIKMMG 832
I V+ HLAP+LP H V+ + + + +VS+AP+GS+SILPIS+AYIKMMG
Sbjct: 764 GPGMGPIGVKKHLAPFLPNHPVISLKRNEDA-CPVGTVSAAPWGSSSILPISWAYIKMMG 822
Query: 833 SKGLPFSSVIAMLNANYMMSRLRPHYNILFVGEKGSTTETEDLTHCGHEFIIDLRAY-KD 891
KGL ++ A+LNANYM RL HY ILF G +G + GHEFI+D R + K
Sbjct: 823 GKGLKQATETAILNANYMAKRLETHYRILFRGARG---------YVGHEFILDTRPFKKS 873
Query: 892 QGVEAIDVAKRLQDYGFHAPTLAFPVPGTLMVXXXXXXXXXXXXRFIDAMISIKKEIDLF 951
+EA+DVAKRLQDYGFHAPT+++PV GTLMV RF DAMISI++EI
Sbjct: 874 ANIEAVDVAKRLQDYGFHAPTMSWPVAGTLMVEPTESEDKAELDRFCDAMISIRQEIADI 933
Query: 952 IKG--DPQGQVLKNSPHSLEDVVSSDDWSSRGYTREQAVYPLPYLK-YNKFWPPVARLDD 1008
+G DP+ LK SPHSL V SS W R Y+RE A +PLP++K NKFWP +AR+DD
Sbjct: 934 EEGRIDPRVNPLKMSPHSLTCVTSS-HW-DRPYSREVAAFPLPFMKPENKFWPTIARIDD 991
Query: 1009 TYGDTHLMCTCPSVE 1023
YGD HL+CTCP +E
Sbjct: 992 IYGDQHLVCTCPPME 1006
>7299318 [E] KOG2040 Glycine dehydrogenase (decarboxylating)
Length = 985
Score = 917 bits (2371), Expect = 0.0
Identities = 489/971 (50%), Positives = 658/971 (67%), Gaps = 37/971 (3%)
Query: 63 FQRRHLGPSPSNVDQMLKQLGYTDLDQFINGVVPENILVKRPLELNSPENGFTEQQMLKH 122
F RH+GP ++V ML LG+ L + VP++I +KR L+L+ P N E ++++
Sbjct: 37 FPSRHIGPRKTDVVAMLDTLGFKSLAELTEKAVPQSIQLKRELDLDKPLN---EHELIRR 93
Query: 123 LEELANKNNHKVRNFIGKGYYGTVLPPVIQRNLLECPEWYTSYTPYQPEISQGRLESLLN 182
+ +++ KN R++IG GY+ +P I RN+ E P W T YTPYQPEI+QGRLESLLN
Sbjct: 94 IRDISLKNQ-LWRSYIGMGYHNCHVPHTIIRNMFENPGWTTQYTPYQPEIAQGRLESLLN 152
Query: 183 YQTVVSDLTGLPVANASLLDEGTAAGEAMLLSFNVAKKKKLTYVIDKRLHKQTKSVLKTR 242
YQT+V+DLTGL VANASLLDEGTAA EAM L+ K+KKL + R+H QT SV+KTR
Sbjct: 153 YQTLVTDLTGLDVANASLLDEGTAAAEAMCLATRHNKRKKL--YLSNRVHPQTLSVVKTR 210
Query: 243 TEPFGIKLVEVDPLDESTWSVLSSDKDVSGCLVQYPDTEGNIIPGETLAKLADIVHQSKG 302
TE +++V V P++++ ++++G L+QYPDT G++ E +A LA ++
Sbjct: 211 TEALELEIV-VGPIEQADLP----SRELAGILLQYPDTYGDVKDFEDIAALAK---KNGT 262
Query: 303 LFAVASDLLALTLLKPPAQFGADIVLGSSQRFGVPFGYGGPHAAFFSVIEKLNRKIPGRI 362
L VA+DLL+LTLL+PPA+FGADI +G+SQR GVP GYGGPHA FF+ + L R +PGR+
Sbjct: 263 LVVVATDLLSLTLLRPPAEFGADIAVGTSQRLGVPLGYGGPHAGFFACKQSLVRLMPGRM 322
Query: 363 VGVSKDRLGKPALRLALQTREQHIKRDKATSNICTAQALLANIAANYCVYHGPQGLKEIA 422
+GV++D G A RLALQTREQHI+RDKATSNICTAQALLAN++A Y +YHGP+GLK +A
Sbjct: 323 IGVTRDMDGNDAYRLALQTREQHIRRDKATSNICTAQALLANMSAMYAIYHGPEGLKAMA 382
Query: 423 GRVYGFTTVLANGLSSSNHTLLNKSWFDTLTVELNGISAQDFIKTAVDKYQINLYQVNNE 482
R++ FT L G+ + H ++NK++FDTL + L G + + +K + +INL + ++
Sbjct: 383 NRIHHFTLTLQTGVLGAGHEVINKNFFDTLHIRLGGGQSLEDLKERAEHKRINLRYLEDD 442
Query: 483 TVSLSLDETVTKDDLIALLELFGCNAN-ELPVALPEFPQ------ELTRQDEILSNEVFN 535
TV ++LDETV+ D+ LL +F A+ E +A + + + R L + +F
Sbjct: 443 TVGVALDETVSVADVDDLLWVFKAEASVEHILARKDVLKNSIENSKFLRTSPYLQHPIFQ 502
Query: 536 THHSETAMLRYLHRLQSRDLSLANSMIPLGSCTMKLNATVEMIPITWPQFANIHPFQPRD 595
++HSE+ M+RY+ +L+++D+SL +SMIPLGSCTMKLN+T EM+P ++ F +IHPF P +
Sbjct: 503 SYHSESRMVRYMKKLENKDISLVHSMIPLGSCTMKLNSTTEMMPCSFRHFTDIHPFAPVE 562
Query: 596 QVEGYEVLIKNLEKDLASITGFDEVSLQPNSGAQGEYAGLRVIRRYFEDRGETHRNICLI 655
Q +G+ + K LE DL ITG+D +S QPNSGAQGEYAGLR IR Y E R E HRNICLI
Sbjct: 563 QAQGFHQMFKELEHDLCEITGYDRISFQPNSGAQGEYAGLRAIRSYHEHRNEGHRNICLI 622
Query: 656 PVSAHGTNPASAAMCGLKVIPVNCLKNGSLDLVDLKAKAEKHKDNLAAIMITYPSTYGLF 715
P+SAHGTNPASA M G+KV P+ L NGS+D+ L+AKAE+H L+ +MITYPST G+F
Sbjct: 623 PISAHGTNPASAQMAGMKVEPIRILSNGSIDMAHLRAKAEEHAHELSCLMITYPSTMGVF 682
Query: 716 EPGVRTAIDLVHENGGQVYLDGANMNAQVGLTSPGDLNADVCHLNLHKTFSIXXXXXXXX 775
E V L+H++GGQVYLDGANMNAQVGL PGD +DV HLNLHKTF I
Sbjct: 683 EETVADICTLIHKHGGQVYLDGANMNAQVGLCRPGDYGSDVSHLNLHKTFCIPHGGGGPG 742
Query: 776 XXXICVQSHLAPYLPAHDVVPMITGVGSDKSIASVSSAPYGSASILPISYAYIKMMGSKG 835
I V++HLAPYLP H VV ++ + S VS+AP+GS++ILPIS++YIK+MGS+G
Sbjct: 743 MGPIGVKAHLAPYLPGHPVVSPLS--SEEHSFGVVSAAPFGSSAILPISWSYIKLMGSRG 800
Query: 836 LPFSSVIAMLNANYMMSRLRPHYNILFVGEKGSTTETEDLTHCGHEFIIDLR-AYKDQGV 894
L ++ +A+LNANYM RL HY L+ HEFI+D+R K +
Sbjct: 801 LKRATQVAILNANYMSKRLEQHYKTLYKAPNSQLV--------AHEFILDIRDLKKSANI 852
Query: 895 EAIDVAKRLQDYGFHAPTLAFPVPGTLMVXXXXXXXXXXXXRFIDAMISIKKEIDLFIKG 954
EA+DVAKRL DYGFHAPT+++PV GTLM+ RF DAMISI++EI G
Sbjct: 853 EAVDVAKRLMDYGFHAPTMSWPVAGTLMIEPTESEDKEELDRFCDAMISIREEIAEIEAG 912
Query: 955 --DPQGQVLKNSPHSLEDVVSSDDWSSRGYTREQAVYPLPYLKYN-KFWPPVARLDDTYG 1011
D LK SPH+ V+ SD W R YTREQA +P ++K + K WP V R+DD YG
Sbjct: 913 RMDKAVNPLKMSPHTQAQVI-SDKW-DRPYTREQAAFPAIFVKPDAKIWPTVGRIDDAYG 970
Query: 1012 DTHLMCTCPSV 1022
D HL+CTCP +
Sbjct: 971 DKHLVCTCPPI 981
>CE02846 [E] KOG2040 Glycine dehydrogenase (decarboxylating)
Length = 979
Score = 875 bits (2261), Expect = 0.0
Identities = 474/980 (48%), Positives = 631/980 (64%), Gaps = 48/980 (4%)
Query: 61 DTFQRRHLGPSPSNVDQMLKQLGYTDLDQFINGVVPENILVKRPLELNSPENGFTEQQML 120
D F RH+GP QML +GY DLD VP I ++ LEL +P E +ML
Sbjct: 28 DAFVDRHIGPRRLEQQQMLDFIGYKDLDDLTGTNVPNMIKAEKALELPAP---LDEYKML 84
Query: 121 KHLEELANKNNHKVRNFIGKGYYGTVLPPVIQRNLLECPEWYTSYTPYQPEISQGRLESL 180
K LE +A +N R++IG GYY T++P VI RN+L+ W + YTPYQ EISQGRLESL
Sbjct: 85 KELEAIAAQNKI-YRSYIGMGYYDTIVPAVISRNILQNIGWISQYTPYQAEISQGRLESL 143
Query: 181 LNYQTVVSDLTGLPVANASLLDEGTAAGEAMLLSFNVAKKKKLTYVIDKRLHKQTKSVLK 240
LN+QT+++++TGLP NASLLDE TA+ EA+ L+ K+ K+ V+D H Q V++
Sbjct: 144 LNFQTMIAEMTGLPTTNASLLDEATASAEAVALAARTTKRNKI--VVDSFCHPQNLDVIR 201
Query: 241 TRTEPFGIKLVEVDPLDESTWSVLSSDKDVSGCLVQYPDTEGNIIPGETLAKLADIVHQS 300
TR+ P GI + D ++ + D V+ +VQYP+TEG I +L + H++
Sbjct: 202 TRSGPLGIDIEVSDSIEGYAF-----DDKVAAVVVQYPNTEGRI---HQFDELIESAHKN 253
Query: 301 KGLFAVASDLLALTLLKPPAQFGADIVLGSSQRFGVPFGYGGPHAAFFSVIEK-----LN 355
K L + DLL+LT+L+ P GADI +GS+QRFGVP GYGGPHA F +V + L
Sbjct: 254 KSLVIMVCDLLSLTILRSPGDLGADIAVGSAQRFGVPLGYGGPHAGFMAVAKHDAKNALG 313
Query: 356 RKIPGRIVGVSKDRLGKPALRLALQTREQHIKRDKATSNICTAQALLANIAANYCVYHGP 415
R IPGRI+GV+KD G ALRLALQTREQHI+RDKATSNICTAQALLAN++A Y VYHGP
Sbjct: 314 RNIPGRIIGVTKDANGNRALRLALQTREQHIRRDKATSNICTAQALLANMSAMYAVYHGP 373
Query: 416 QGLKEIAGRVYGFTTVLANGLSSSNHTLLNKSWFDTLTVELNGISAQDFIKTAVDKYQIN 475
Q L EIA V+ T LA L ++ H +++K +FDTL + L +A + K ++ ++N
Sbjct: 374 QRLTEIARGVHKSTAYLAYHLRNAGHEIVHKDYFDTLKIRLKDKAALEETKKRAEEMKMN 433
Query: 476 LYQVNNETVSLSLDETVTKDDLIALLELFGCNANELPVALPEFPQEL----------TRQ 525
+ + +SLDETV +DL+ ++ + L E E+ +R
Sbjct: 434 FRYYEDGDIGVSLDETVKSEDLMDIIYTLNGATEKDVTKLREERWEVACPLIGNSPHSRS 493
Query: 526 DEILSNEVFNTHHSETAMLRYLHRLQSRDLSLANSMIPLGSCTMKLNATVEMIPITWPQF 585
L + VFNTH SE ++RY+ RL+++D+SL +SMIPLGSCTMKLNA+ E+IPITWP
Sbjct: 494 SLFLQHPVFNTHQSEQQLVRYMKRLENKDVSLVHSMIPLGSCTMKLNASAELIPITWPTL 553
Query: 586 ANIHPFQPRDQVEGYEVLIKNLEKDLASITGFDEVSLQPNSGAQGEYAGLRVIRRYFEDR 645
++IHPF P +Q +GY + +LEK L ITG+D SLQPNSGA GEYAGL IR Y +
Sbjct: 554 SSIHPFAPVEQAKGYSRIFGDLEKWLCEITGYDNFSLQPNSGANGEYAGLLAIRNYLIHK 613
Query: 646 GETHRNICLIPVSAHGTNPASAAMCGLKVIPVNCLKNGSLDLVDLKAKAEKHKDNLAAIM 705
GE RNICLIP SAHGTNPASA M +KV+ V+ +G+++ DL AKAEK+ + LAAIM
Sbjct: 614 GEEQRNICLIPTSAHGTNPASAQMANMKVVVVDSDHHGNINYKDLAAKAEKYSNQLAAIM 673
Query: 706 ITYPSTYGLFEPGVRTAIDLVHENGGQVYLDGANMNAQVGLTSPGDLNADVCHLNLHKTF 765
+TYPST+G+FE +R D VHE+GGQVYLDGANMNAQVGL PGD +DV HLNLHKTF
Sbjct: 674 VTYPSTHGVFESSIRDVCDKVHEHGGQVYLDGANMNAQVGLCRPGDYGSDVSHLNLHKTF 733
Query: 766 SIXXXXXXXXXXXICVQSHLAPYLPAHDVVPMITGVGSDKSIASVSSAPYGSASILPISY 825
I I V+ HLAP+LP H VVP+ + + SV+SAPYGSASIL I++
Sbjct: 734 CIPHGGGGPGVGPIGVKKHLAPFLPGHSVVPV-----DGRKVGSVASAPYGSASILAITW 788
Query: 826 AYIKMMGSKGLPFSSVIAMLNANYMMSRLRPHYNILFVGEKGSTTETEDLTHCGHEFIID 885
AYI+MMG GL +S +A+LNANYM RL Y I++ E+G HEFI+D
Sbjct: 789 AYIRMMGPVGLREASQVAILNANYMAKRLENDYRIVYKDEQGLV---------AHEFIMD 839
Query: 886 LRAYKDQGVEAIDVAKRLQDYGFHAPTLAFPVPGTLMVXXXXXXXXXXXXRFIDAMISIK 945
+ +K G+E +D+AKRL DYGFH+PT+++PV LM+ R ++A++SI+
Sbjct: 840 CKPFKKHGIEVVDIAKRLMDYGFHSPTMSWPVHDCLMIEPTESEDKAEMDRLVEALLSIR 899
Query: 946 KEIDLFIKG--DPQGQVLKNSPHSLEDVVSSDDWSSRGYTREQAVYPLPYLKYNKFWPPV 1003
+EI G D LK +PH+LE V+SD+W + Y+RE A +P P+ + K WP V
Sbjct: 900 EEIRQVENGSLDKHLNPLKMAPHTLEK-VTSDNW-NMPYSRELAAFPKPWCTH-KAWPTV 956
Query: 1004 ARLDDTYGDTHLMCTCPSVE 1023
R+DD YGD +L+CTCP +E
Sbjct: 957 GRVDDQYGDRNLVCTCPPIE 976
>Hs20471026 [E] KOG2040 Glycine dehydrogenase (decarboxylating)
Length = 339
Score = 305 bits (780), Expect = 3e-82
Identities = 159/305 (52%), Positives = 212/305 (69%), Gaps = 11/305 (3%)
Query: 307 ASDLLALTLLKPPAQFGADIVLGSSQRFGVPFGYGGPHAAFFSVIEKLNRKIPGRIVGVS 366
A+DLLAL +L+PP +FG DI LGSSQRFGVP GYGGPHAAFF+V E L R +PGR+VG +
Sbjct: 37 ATDLLALCILRPPGEFGVDIALGSSQRFGVPLGYGGPHAAFFAVRESLVRMMPGRMVGAT 96
Query: 367 KDRLGKPALRLALQTREQHIKRDKATSNICTAQALLANIAANYCVYHGPQGLKEIAGRVY 426
+D GK LALQTREQH +RD ATSNICTAQALLAN+AA + +YHG GL+ IA RV+
Sbjct: 97 RDATGKEVYCLALQTREQHTERDMATSNICTAQALLANMAAMFAIYHGSHGLEHIARRVH 156
Query: 427 GFTTVLANGLSSSNHTLLNKSWFDTLTVELNGISAQDFIKTAVDKYQINLYQVNNETVSL 486
T +L GL + H L + +FDTL ++ G S ++ + A + QIN + T+ +
Sbjct: 157 NATLILPEGLKRAGHQLQHDVFFDTLKIQC-GCSVKEVLGRAAQR-QINFRLFEDGTLGI 214
Query: 487 SLDETVTKDDLIALLELFGCNANELPVALPEFPQE--------LTRQDEILSNEVFNTHH 538
SLDETV + DL LL +F C ++ VA +E R L+++VFN++H
Sbjct: 215 SLDETVNEKDLDDLLRIFVCESSAELVA-ESMGEECRGIPGSVFKRTSPFLTHQVFNSYH 273
Query: 539 SETAMLRYLHRLQSRDLSLANSMIPLGSCTMKLNATVEMIPITWPQFANIHPFQPRDQVE 598
SET ++RY+ +L+++D+SL +SMIPLGSCTMKLN++ E+ PITW +FANIHPF P DQ +
Sbjct: 274 SETNIVRYMKKLENKDISLVHSMIPLGSCTMKLNSSSELAPITWKEFANIHPFVPLDQAQ 333
Query: 599 GYEVL 603
GY+ L
Sbjct: 334 GYQQL 338
Database: KOG eukaryal database 04/03
Posted date: Apr 14, 2003 1:07 PM
Number of letters in database: 30,389,216
Number of sequences in database: 60,738
Lambda K H
0.318 0.136 0.396
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 60,895,197
Number of Sequences: 60738
Number of extensions: 2673070
Number of successful extensions: 6158
Number of sequences better than 1.0e-05: 9
Number of HSP's better than 0.0 without gapping: 9
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 6064
Number of HSP's gapped (non-prelim): 9
length of query: 1028
length of database: 30,389,216
effective HSP length: 117
effective length of query: 911
effective length of database: 23,282,870
effective search space: 21210694570
effective search space used: 21210694570
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)