ORF STATUS Function Best COG Functional category Pathways and functional systems
r_klactIV3283 good O KOG0019 Posttranslational modification, protein turnover, chaperones Molecular chaperone (HSP90 family)
Only best alignment is shown:
BLASTP 2.2.3 [May-13-2002]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= r_klactIV3283 1109728 1107590 -713
(713 letters)
Database: KOG eukaryal database 04/03
60,738 sequences; 30,389,216 total letters
Searching..................................................done
Color Key for Alignment Scores: 
Score E
Sequences producing significant alignments: (bits) Value
YMR186w [O] KOG0019 Molecular chaperone (HSP90 family) 667 0.0
YPL240c [O] KOG0019 Molecular chaperone (HSP90 family) 663 0.0
SPAC926.04c [O] KOG0019 Molecular chaperone (HSP90 family) 547 e-155
At5g52640 [O] KOG0019 Molecular chaperone (HSP90 family) 491 e-138
At5g56030 [O] KOG0019 Molecular chaperone (HSP90 family) 486 e-137
At5g56010 [O] KOG0019 Molecular chaperone (HSP90 family) 486 e-137
At5g56000 [O] KOG0019 Molecular chaperone (HSP90 family) 480 e-135
Hs20149594 [O] KOG0019 Molecular chaperone (HSP90 family) 457 e-128
Hs13129150 [O] KOG0019 Molecular chaperone (HSP90 family) 451 e-126
7292327 [O] KOG0019 Molecular chaperone (HSP90 family) 448 e-125
CE05441 [O] KOG0019 Molecular chaperone (HSP90 family) 441 e-123
At4g24190 [O] KOG0020 Endoplasmic reticulum glucose-regulated pr... 341 2e-93
Hs4507677 [O] KOG0020 Endoplasmic reticulum glucose-regulated pr... 337 4e-92
CE06362 [O] KOG0020 Endoplasmic reticulum glucose-regulated prot... 331 3e-90
7301648 [O] KOG0020 Endoplasmic reticulum glucose-regulated prot... 314 3e-85
At2g04030 [O] KOG0019 Molecular chaperone (HSP90 family) 306 5e-83
At3g07770 [O] KOG0019 Molecular chaperone (HSP90 family) 293 5e-79
Hs22065017 [O] KOG0019 Molecular chaperone (HSP90 family) 290 7e-78
ECU02g1100 [O] KOG0019 Molecular chaperone (HSP90 family) 263 9e-70
Hs22043581 [O] KOG0020 Endoplasmic reticulum glucose-regulated p... 221 3e-57
7302271 [O] KOG0019 Molecular chaperone (HSP90 family) 190 7e-48
Hs16157901 [O] KOG0019 Molecular chaperone (HSP90 family) 187 6e-47
Hs20535880 [O] KOG0019 Molecular chaperone (HSP90 family) 179 1e-44
Hs7706485 [O] KOG0019 Molecular chaperone (HSP90 family) 174 3e-43
Hs22041160 [O] KOG0019 Molecular chaperone (HSP90 family) 165 3e-40
CE29455 [O] KOG0019 Molecular chaperone (HSP90 family) 164 4e-40
Hs22041746 [O] KOG0019 Molecular chaperone (HSP90 family) 144 4e-34
Hs17451483 [O] KOG0019 Molecular chaperone (HSP90 family) 143 8e-34
Hs20545837_2 [O] KOG0019 Molecular chaperone (HSP90 family) 115 3e-25
Hs22059125 [O] KOG0019 Molecular chaperone (HSP90 family) 100 1e-20
Hs17448897 [O] KOG0019 Molecular chaperone (HSP90 family) 98 5e-20
Hs18549738 [O] KOG0019 Molecular chaperone (HSP90 family) 92 4e-18
Hs20471111 [O] KOG0019 Molecular chaperone (HSP90 family) 72 2e-12
Hs18550811 [O] KOG0019 Molecular chaperone (HSP90 family) 68 4e-11
>YMR186w [O] KOG0019 Molecular chaperone (HSP90 family)
Length = 705
Score = 667 bits (1720), Expect = 0.0
Identities = 340/405 (83%), Positives = 360/405 (87%)
Query: 279 PLWTKNPSEVTQEEYNAFYKSISNDWEDPLAVKHFSVEGQLEFKAILFVPKRAAFDLFES 338
PLWT+NPS++TQEEYNAFYKSISNDWEDPL VKHFSVEGQLEF+AILF+PKRA FDLFES
Sbjct: 271 PLWTRNPSDITQEEYNAFYKSISNDWEDPLYVKHFSVEGQLEFRAILFIPKRAPFDLFES 330
Query: 339 KKKKTNIKLYVRRVFITDEAEELIPEWLSFVKGVVDSEDLPLNLSREMLQQXXXXXXXXX 398
KKKK NIKLYVRRVFITDEAE+LIPEWLSFVKGVVDSEDLPLNLSREMLQQ
Sbjct: 331 KKKKNNIKLYVRRVFITDEAEDLIPEWLSFVKGVVDSEDLPLNLSREMLQQNKIMKVIRK 390
Query: 399 XXXXXXXETFNEIAEDSEQFDKFYTAFSKNIKLGIHEDTQNRAALAKLLRYNSTKSVDEL 458
E FNEIAEDSEQFDKFY+AF+KNIKLG+HEDTQNRAALAKLLRYNSTKSVDEL
Sbjct: 391 NIVKKLIEAFNEIAEDSEQFDKFYSAFAKNIKLGVHEDTQNRAALAKLLRYNSTKSVDEL 450
Query: 459 TSLSDYVTRMPEHQKNIYFITGESIKAVEKSPFLDALKAKNFEVLFLVDPIDEYAFSQLK 518
TSL+DYVTRMPEHQKNIY+ITGES+KAVEKSPFLDALKAKNFEVLFL DPIDEYAF+QLK
Sbjct: 451 TSLTDYVTRMPEHQKNIYYITGESLKAVEKSPFLDALKAKNFEVLFLTDPIDEYAFTQLK 510
Query: 519 EFEGKQLVDITKDFXXXXXXXXXXXXXXXXXXXXPLTTALKEILGDQVEKVVVSHKLLDA 578
EFEGK LVDITKDF PLT ALK+ILGDQVEKVVVS+KLLDA
Sbjct: 511 EFEGKTLVDITKDFELEETDEEKAEREKEIKEYEPLTKALKDILGDQVEKVVVSYKLLDA 570
Query: 579 PAAIRTGQFGWSANMERIMKAQALRDSSMSSYMASKKIFEISPKSPIIRELKNKVEEGGA 638
PAAIRTGQFGWSANMERIMKAQALRDSSMSSYM+SKK FEISPKSPII+ELK +V+EGGA
Sbjct: 571 PAAIRTGQFGWSANMERIMKAQALRDSSMSSYMSSKKTFEISPKSPIIKELKKRVDEGGA 630
Query: 639 QDKTVKDLTNLLFETALLTSGFSLEEPSSFASRINRLISLGLNID 683
QDKTVKDLTNLLFETALLTSGFSLEEP+SFASRINRLISLGLNID
Sbjct: 631 QDKTVKDLTNLLFETALLTSGFSLEEPTSFASRINRLISLGLNID 675
Score = 383 bits (983), Expect = e-106
Identities = 195/207 (94%), Positives = 205/207 (98%)
Query: 5 ETYEFQAEITQLMSLIINTVYSNKEIFLRELISNASDALDKIRYQSLSDPKVLETEPELF 64
ET+EFQAEITQLMSLIINTVYSNKEIFLRELISNASDALDKIRYQ+LSDPK LETEP+LF
Sbjct: 4 ETFEFQAEITQLMSLIINTVYSNKEIFLRELISNASDALDKIRYQALSDPKQLETEPDLF 63
Query: 65 IRITPRPEEKVLEIRDSGIGMTKAELINNLGTIAKSGTKAFMEALSAGADVSMIGQFGVG 124
IRITP+PEEKVLEIRDSGIGMTKAELINNLGTIAKSGTKAFMEALSAGADVSMIGQFGVG
Sbjct: 64 IRITPKPEEKVLEIRDSGIGMTKAELINNLGTIAKSGTKAFMEALSAGADVSMIGQFGVG 123
Query: 125 FYSLFLVADRVQVISKHNDDEQYIWESNAGGSFTVTLDESNERIGRGTVLRLFLKEDQLE 184
FYSLFLVADRVQVISK+N+DEQYIWESNAGGSFTVTLDE NERIGRGTVLRLFLK+DQLE
Sbjct: 124 FYSLFLVADRVQVISKNNEDEQYIWESNAGGSFTVTLDEVNERIGRGTVLRLFLKDDQLE 183
Query: 185 YLEEKRIKDVVKKHSEFVAYPIQLLVT 211
YLEEKRIK+V+K+HSEFVAYPIQLLVT
Sbjct: 184 YLEEKRIKEVIKRHSEFVAYPIQLLVT 210
>YPL240c [O] KOG0019 Molecular chaperone (HSP90 family)
Length = 709
Score = 663 bits (1710), Expect = 0.0
Identities = 338/405 (83%), Positives = 359/405 (88%)
Query: 279 PLWTKNPSEVTQEEYNAFYKSISNDWEDPLAVKHFSVEGQLEFKAILFVPKRAAFDLFES 338
PLWT+NPS++TQEEYNAFYKSISNDWEDPL VKHFSVEGQLEF+AILF+PKRA FDLFES
Sbjct: 275 PLWTRNPSDITQEEYNAFYKSISNDWEDPLYVKHFSVEGQLEFRAILFIPKRAPFDLFES 334
Query: 339 KKKKTNIKLYVRRVFITDEAEELIPEWLSFVKGVVDSEDLPLNLSREMLQQXXXXXXXXX 398
KKKK NIKLYVRRVFITDEAE+LIPEWLSFVKGVVDSEDLPLNLSREMLQQ
Sbjct: 335 KKKKNNIKLYVRRVFITDEAEDLIPEWLSFVKGVVDSEDLPLNLSREMLQQNKIMKVIRK 394
Query: 399 XXXXXXXETFNEIAEDSEQFDKFYTAFSKNIKLGIHEDTQNRAALAKLLRYNSTKSVDEL 458
E FNEIAEDSEQF+KFY+AFSKNIKLG+HEDTQNRAALAKLLRYNSTKSVDEL
Sbjct: 395 NIVKKLIEAFNEIAEDSEQFEKFYSAFSKNIKLGVHEDTQNRAALAKLLRYNSTKSVDEL 454
Query: 459 TSLSDYVTRMPEHQKNIYFITGESIKAVEKSPFLDALKAKNFEVLFLVDPIDEYAFSQLK 518
TSL+DYVTRMPEHQKNIY+ITGES+KAVEKSPFLDALKAKNFEVLFL DPIDEYAF+QLK
Sbjct: 455 TSLTDYVTRMPEHQKNIYYITGESLKAVEKSPFLDALKAKNFEVLFLTDPIDEYAFTQLK 514
Query: 519 EFEGKQLVDITKDFXXXXXXXXXXXXXXXXXXXXPLTTALKEILGDQVEKVVVSHKLLDA 578
EFEGK LVDITKDF PLT ALKEILGDQVEKVVVS+KLLDA
Sbjct: 515 EFEGKTLVDITKDFELEETDEEKAEREKEIKEYEPLTKALKEILGDQVEKVVVSYKLLDA 574
Query: 579 PAAIRTGQFGWSANMERIMKAQALRDSSMSSYMASKKIFEISPKSPIIRELKNKVEEGGA 638
PAAIRTGQFGWSANMERIMKAQALRDSSMSSYM+SKK FEISPKSPII+ELK +V+EGGA
Sbjct: 575 PAAIRTGQFGWSANMERIMKAQALRDSSMSSYMSSKKTFEISPKSPIIKELKKRVDEGGA 634
Query: 639 QDKTVKDLTNLLFETALLTSGFSLEEPSSFASRINRLISLGLNID 683
QDKTVKDLT LL+ETALLTSGFSL+EP+SFASRINRLISLGLNID
Sbjct: 635 QDKTVKDLTKLLYETALLTSGFSLDEPTSFASRINRLISLGLNID 679
Score = 380 bits (977), Expect = e-105
Identities = 193/207 (93%), Positives = 204/207 (98%)
Query: 5 ETYEFQAEITQLMSLIINTVYSNKEIFLRELISNASDALDKIRYQSLSDPKVLETEPELF 64
ET+EFQAEITQLMSLIINTVYSNKEIFLRELISNASDALDKIRY+SLSDPK LETEP+LF
Sbjct: 4 ETFEFQAEITQLMSLIINTVYSNKEIFLRELISNASDALDKIRYKSLSDPKQLETEPDLF 63
Query: 65 IRITPRPEEKVLEIRDSGIGMTKAELINNLGTIAKSGTKAFMEALSAGADVSMIGQFGVG 124
IRITP+PE+KVLEIRDSGIGMTKAELINNLGTIAKSGTKAFMEALSAGADVSMIGQFGVG
Sbjct: 64 IRITPKPEQKVLEIRDSGIGMTKAELINNLGTIAKSGTKAFMEALSAGADVSMIGQFGVG 123
Query: 125 FYSLFLVADRVQVISKHNDDEQYIWESNAGGSFTVTLDESNERIGRGTVLRLFLKEDQLE 184
FYSLFLVADRVQVISK NDDEQYIWESNAGGSFTVTLDE NERIGRGT+LRLFLK+DQLE
Sbjct: 124 FYSLFLVADRVQVISKSNDDEQYIWESNAGGSFTVTLDEVNERIGRGTILRLFLKDDQLE 183
Query: 185 YLEEKRIKDVVKKHSEFVAYPIQLLVT 211
YLEEKRIK+V+K+HSEFVAYPIQL+VT
Sbjct: 184 YLEEKRIKEVIKRHSEFVAYPIQLVVT 210
>SPAC926.04c [O] KOG0019 Molecular chaperone (HSP90 family)
Length = 704
Score = 547 bits (1410), Expect = e-155
Identities = 275/406 (67%), Positives = 324/406 (79%), Gaps = 1/406 (0%)
Query: 279 PLWTKNPSEVTQEEYNAFYKSISNDWEDPLAVKHFSVEGQLEFKAILFVPKRAAFDLFES 338
P+WT+NPSEVT+EEY +FYKS++NDWED LAVKHFSVEGQLEF+AILFVP+RA DLFE+
Sbjct: 270 PIWTRNPSEVTKEEYASFYKSLTNDWEDHLAVKHFSVEGQLEFRAILFVPRRAPMDLFEA 329
Query: 339 KKKKTNIKLYVRRVFITDEAEELIPEWLSFVKGVVDSEDLPLNLSREMLQQXXXXXXXXX 398
K+KK NIKLYVRRVFITD+ EELIPEWL F+KGVVDSEDLPLNLSREMLQQ
Sbjct: 330 KRKKNNIKLYVRRVFITDDCEELIPEWLGFIKGVVDSEDLPLNLSREMLQQNKIMKVIRK 389
Query: 399 XXXXXXXETFNEIAEDSEQFDKFYTAFSKNIKLGIHEDTQNRAALAKLLRYNSTKSVDEL 458
+ FNEIAED E F FY AFSKN+KLGIHED NR ALAKLLRYNS S D+L
Sbjct: 390 NLVRRCLDMFNEIAEDKENFKTFYDAFSKNLKLGIHEDAANRPALAKLLRYNSLNSPDDL 449
Query: 459 TSLSDYVTRMPEHQKNIYFITGESIKAVEKSPFLDALKAKNFEVLFLVDPIDEYAFSQLK 518
SL DY+T+MPEHQKNIYFITGES +AVE SPFL+ +AK F+VLF+VDPIDEYA +QLK
Sbjct: 450 ISLEDYITKMPEHQKNIYFITGESKQAVENSPFLEIFRAKKFDVLFMVDPIDEYAVTQLK 509
Query: 519 EFEGKQLVDITKD-FXXXXXXXXXXXXXXXXXXXXPLTTALKEILGDQVEKVVVSHKLLD 577
EFEGK+LV+ITKD LK ILGD+VEKVVVS+K++
Sbjct: 510 EFEGKKLVNITKDGLELEETDEEKAAREKLEKEYEEFAKQLKTILGDKVEKVVVSNKIVG 569
Query: 578 APAAIRTGQFGWSANMERIMKAQALRDSSMSSYMASKKIFEISPKSPIIRELKNKVEEGG 637
+P + TGQ+GWSANMERIMKAQALRD+SMS+YM+S+K FEI+PKSPII ELK KVEE G
Sbjct: 570 SPCLLTTGQYGWSANMERIMKAQALRDTSMSAYMSSRKTFEINPKSPIIAELKKKVEENG 629
Query: 638 AQDKTVKDLTNLLFETALLTSGFSLEEPSSFASRINRLISLGLNID 683
A+D++VKDL +L+ETALL+SGF+L++PS++A RINRLISLGL+ID
Sbjct: 630 AEDRSVKDLATILYETALLSSGFTLDDPSAYAQRINRLISLGLSID 675
Score = 333 bits (853), Expect = 7e-91
Identities = 165/211 (78%), Positives = 188/211 (88%)
Query: 1 MVNQETYEFQAEITQLMSLIINTVYSNKEIFLRELISNASDALDKIRYQSLSDPKVLETE 60
M N ET++F+AEI+QLMSLIINTVYSNKEIFLRELISNASDALDKIRYQSLSDP L+ E
Sbjct: 1 MSNTETFKFEAEISQLMSLIINTVYSNKEIFLRELISNASDALDKIRYQSLSDPHALDAE 60
Query: 61 PELFIRITPRPEEKVLEIRDSGIGMTKAELINNLGTIAKSGTKAFMEALSAGADVSMIGQ 120
+LFIRITP E K+L IRD+GIGMTK +LINNLG IAKSGTK FMEA ++GAD+SMIGQ
Sbjct: 61 KDLFIRITPDKENKILSIRDTGIGMTKNDLINNLGVIAKSGTKQFMEAAASGADISMIGQ 120
Query: 121 FGVGFYSLFLVADRVQVISKHNDDEQYIWESNAGGSFTVTLDESNERIGRGTVLRLFLKE 180
FGVGFYS +LVAD+VQV+SKHNDDEQYIWES+AGGSFTVTLD R+ RGT +RLF+KE
Sbjct: 121 FGVGFYSAYLVADKVQVVSKHNDDEQYIWESSAGGSFTVTLDTDGPRLLRGTEIRLFMKE 180
Query: 181 DQLEYLEEKRIKDVVKKHSEFVAYPIQLLVT 211
DQL+YLEEK IKD VKKHSEF++YPIQL+VT
Sbjct: 181 DQLQYLEEKTIKDTVKKHSEFISYPIQLVVT 211
>At5g52640 [O] KOG0019 Molecular chaperone (HSP90 family)
Length = 705
Score = 491 bits (1264), Expect = e-138
Identities = 252/407 (61%), Positives = 309/407 (75%), Gaps = 3/407 (0%)
Query: 279 PLWTKNPSEVTQEEYNAFYKSISNDWEDPLAVKHFSVEGQLEFKAILFVPKRAAFDLFES 338
P+W + P E+T+EEY AFYKS++NDWED LAVKHFSVEGQLEFKAILFVPKRA FDLF++
Sbjct: 272 PIWLRKPEEITKEEYAAFYKSLTNDWEDHLAVKHFSVEGQLEFKAILFVPKRAPFDLFDT 331
Query: 339 KKKKTNIKLYVRRVFITDEAEELIPEWLSFVKGVVDSEDLPLNLSREMLQQXXXXXXXXX 398
+KK NIKLYVRRVFI D EELIPE+LSFVKGVVDS+DLPLN+SRE LQQ
Sbjct: 332 RKKLNNIKLYVRRVFIMDNCEELIPEYLSFVKGVVDSDDLPLNISRETLQQNKILKVIRK 391
Query: 399 XXXXXXXETFNEIAEDSEQFDKFYTAFSKNIKLGIHEDTQNRAALAKLLRYNSTKSVDEL 458
E FNEIAE+ E + KFY AFSKN+KLGIHED+QNR +A LLRY+STKS DE+
Sbjct: 392 NLVKKCIEMFNEIAENKEDYTKFYEAFSKNLKLGIHEDSQNRGKIADLLRYHSTKSGDEM 451
Query: 459 TSLSDYVTRMPEHQKNIYFITGESIKAVEKSPFLDALKAKNFEVLFLVDPIDEYAFSQLK 518
TS DYVTRM E QK+I++ITGES KAVE SPFL+ LK + +EVL++VD IDEYA QLK
Sbjct: 452 TSFKDYVTRMKEGQKDIFYITGESKKAVENSPFLERLKKRGYEVLYMVDAIDEYAVGQLK 511
Query: 519 EFEGKQLVDITKD--FXXXXXXXXXXXXXXXXXXXXPLTTALKEILGDQVEKVVVSHKLL 576
E++GK+LV TK+ L +KEILGD+VEKVVVS +++
Sbjct: 512 EYDGKKLVSATKEGLKLEDETEEEKKKREEKKKSFENLCKTIKEILGDKVEKVVVSDRIV 571
Query: 577 DAPAAIRTGQFGWSANMERIMKAQALRDSSMSSYMASKKIFEISPKSPIIRELKNKVEEG 636
D+P + TG++GW+ANMERIMKAQALRDSSMS YM+SKK EI+P + I+ EL+ + E
Sbjct: 572 DSPCCLVTGEYGWTANMERIMKAQALRDSSMSGYMSSKKTMEINPDNGIMEELRKRA-EA 630
Query: 637 GAQDKTVKDLTNLLFETALLTSGFSLEEPSSFASRINRLISLGLNID 683
DK+VKDL LL+ETALLTSGFSL+EP++FA+RI+R++ LGL+ID
Sbjct: 631 DKNDKSVKDLVMLLYETALLTSGFSLDEPNTFAARIHRMLKLGLSID 677
Score = 306 bits (785), Expect = 5e-83
Identities = 151/208 (72%), Positives = 177/208 (84%)
Query: 1 MVNQETYEFQAEITQLMSLIINTVYSNKEIFLRELISNASDALDKIRYQSLSDPKVLETE 60
M + ET+ FQAEI QL+SLIINT YSNKEIFLRELISN+SDALDKIR++SL+D L+ +
Sbjct: 6 MADAETFAFQAEINQLLSLIINTFYSNKEIFLRELISNSSDALDKIRFESLTDKSKLDGQ 65
Query: 61 PELFIRITPRPEEKVLEIRDSGIGMTKAELINNLGTIAKSGTKAFMEALSAGADVSMIGQ 120
PELFIR+ P K L I DSGIGMTKA+L+NNLGTIA+SGTK FMEAL AGADVSMIGQ
Sbjct: 66 PELFIRLVPDKSNKTLSIIDSGIGMTKADLVNNLGTIARSGTKEFMEALQAGADVSMIGQ 125
Query: 121 FGVGFYSLFLVADRVQVISKHNDDEQYIWESNAGGSFTVTLDESNERIGRGTVLRLFLKE 180
FGVGFYS +LVA++V V +KHNDDEQY+WES AGGSFTVT D E +GRGT + LFLK+
Sbjct: 126 FGVGFYSAYLVAEKVVVTTKHNDDEQYVWESQAGGSFTVTRDVDGEPLGRGTKITLFLKD 185
Query: 181 DQLEYLEEKRIKDVVKKHSEFVAYPIQL 208
DQLEYLEE+R+KD+VKKHSEF++YPI L
Sbjct: 186 DQLEYLEERRLKDLVKKHSEFISYPIYL 213
>At5g56030 [O] KOG0019 Molecular chaperone (HSP90 family)
Length = 699
Score = 486 bits (1251), Expect = e-137
Identities = 248/406 (61%), Positives = 307/406 (75%), Gaps = 2/406 (0%)
Query: 279 PLWTKNPSEVTQEEYNAFYKSISNDWEDPLAVKHFSVEGQLEFKAILFVPKRAAFDLFES 338
P+W + P E+ +EEY AFYKS+SNDWE+ LAVKHFSVEGQLEFKAILFVPKRA FDLF++
Sbjct: 266 PIWMRKPEEINKEEYAAFYKSLSNDWEEHLAVKHFSVEGQLEFKAILFVPKRAPFDLFDT 325
Query: 339 KKKKTNIKLYVRRVFITDEAEELIPEWLSFVKGVVDSEDLPLNLSREMLQQXXXXXXXXX 398
KKK NIKLYVRRVFI D E++IPE+L FVKG+VDSEDLPLN+SRE LQQ
Sbjct: 326 KKKPNNIKLYVRRVFIMDNCEDIIPEYLGFVKGIVDSEDLPLNISRETLQQNKILKVIRK 385
Query: 399 XXXXXXXETFNEIAEDSEQFDKFYTAFSKNIKLGIHEDTQNRAALAKLLRYNSTKSVDEL 458
E F EIAE+ E ++KFY AFSKN+KLGIHED+QNR +A+LLRY+STKS DEL
Sbjct: 386 NLVKKCLELFFEIAENKEDYNKFYEAFSKNLKLGIHEDSQNRTKIAELLRYHSTKSGDEL 445
Query: 459 TSLSDYVTRMPEHQKNIYFITGESIKAVEKSPFLDALKAKNFEVLFLVDPIDEYAFSQLK 518
TSL DYVTRM E Q +I++ITGES KAVE SPFL+ LK K EVL++VD IDEYA QLK
Sbjct: 446 TSLKDYVTRMKEGQNDIFYITGESKKAVENSPFLEKLKKKGIEVLYMVDAIDEYAIGQLK 505
Query: 519 EFEGKQLVDITKD-FXXXXXXXXXXXXXXXXXXXXPLTTALKEILGDQVEKVVVSHKLLD 577
EFEGK+LV TK+ L +K++LGD+VEKV+VS +++D
Sbjct: 506 EFEGKKLVSATKEGLKLDETEDEKKKKEELKEKFEGLCKVIKDVLGDKVEKVIVSDRVVD 565
Query: 578 APAAIRTGQFGWSANMERIMKAQALRDSSMSSYMASKKIFEISPKSPIIRELKNKVEEGG 637
+P + TG++GW+ANMERIMKAQALRDSSM+ YM+SKK EI+P++ I+ EL+ + +
Sbjct: 566 SPCCLVTGEYGWTANMERIMKAQALRDSSMAGYMSSKKTMEINPENSIMDELRKRA-DAD 624
Query: 638 AQDKTVKDLTNLLFETALLTSGFSLEEPSSFASRINRLISLGLNID 683
DK+VKDL LLFETALLTSGFSL+EP++F SRI+R++ LGL+ID
Sbjct: 625 KNDKSVKDLVLLLFETALLTSGFSLDEPNTFGSRIHRMLKLGLSID 670
Score = 306 bits (785), Expect = 5e-83
Identities = 152/210 (72%), Positives = 178/210 (84%)
Query: 1 MVNQETYEFQAEITQLMSLIINTVYSNKEIFLRELISNASDALDKIRYQSLSDPKVLETE 60
M + ET+ FQAEI QL+SLIINT YSNKEIFLRELISN+SDALDKIR++SL+D L+ +
Sbjct: 1 MADAETFAFQAEINQLLSLIINTFYSNKEIFLRELISNSSDALDKIRFESLTDKSKLDGQ 60
Query: 61 PELFIRITPRPEEKVLEIRDSGIGMTKAELINNLGTIAKSGTKAFMEALSAGADVSMIGQ 120
PELFI I P L I DSGIGMTKA+L+NNLGTIA+SGTK FMEAL+AGADVSMIGQ
Sbjct: 61 PELFIHIIPDKTNNTLTIIDSGIGMTKADLVNNLGTIARSGTKEFMEALAAGADVSMIGQ 120
Query: 121 FGVGFYSLFLVADRVQVISKHNDDEQYIWESNAGGSFTVTLDESNERIGRGTVLRLFLKE 180
FGVGFYS +LVAD+V V +KHNDDEQY+WES AGGSFTVT D S E +GRGT + L+LKE
Sbjct: 121 FGVGFYSAYLVADKVVVTTKHNDDEQYVWESQAGGSFTVTRDTSGETLGRGTKMVLYLKE 180
Query: 181 DQLEYLEEKRIKDVVKKHSEFVAYPIQLLV 210
DQLEYLEE+R+KD+VKKHSEF++YPI L +
Sbjct: 181 DQLEYLEERRLKDLVKKHSEFISYPISLWI 210
>At5g56010 [O] KOG0019 Molecular chaperone (HSP90 family)
Length = 699
Score = 486 bits (1250), Expect = e-137
Identities = 248/406 (61%), Positives = 306/406 (75%), Gaps = 2/406 (0%)
Query: 279 PLWTKNPSEVTQEEYNAFYKSISNDWEDPLAVKHFSVEGQLEFKAILFVPKRAAFDLFES 338
P+W + P E+ +EEY AFYKS+SNDWE+ LAVKHFSVEGQLEFKAILFVPKRA FDLF++
Sbjct: 266 PIWMRKPEEINKEEYAAFYKSLSNDWEEHLAVKHFSVEGQLEFKAILFVPKRAPFDLFDT 325
Query: 339 KKKKTNIKLYVRRVFITDEAEELIPEWLSFVKGVVDSEDLPLNLSREMLQQXXXXXXXXX 398
KKK NIKLYVRRVFI D E++IPE+L FVKG+VDSEDLPLN+SRE LQQ
Sbjct: 326 KKKPNNIKLYVRRVFIMDNCEDIIPEYLGFVKGIVDSEDLPLNISRETLQQNKILKVIRK 385
Query: 399 XXXXXXXETFNEIAEDSEQFDKFYTAFSKNIKLGIHEDTQNRAALAKLLRYNSTKSVDEL 458
E F EIAE+ E ++KFY AFSKN+KLGIHED+QNR +A+LLRY+STKS DEL
Sbjct: 386 NLVKKCLELFFEIAENKEDYNKFYEAFSKNLKLGIHEDSQNRTKIAELLRYHSTKSGDEL 445
Query: 459 TSLSDYVTRMPEHQKNIYFITGESIKAVEKSPFLDALKAKNFEVLFLVDPIDEYAFSQLK 518
TSL DYVTRM E Q +I++ITGES KAVE SPFL+ LK K EVL++VD IDEYA QLK
Sbjct: 446 TSLKDYVTRMKEGQNDIFYITGESKKAVENSPFLEKLKKKGIEVLYMVDAIDEYAIGQLK 505
Query: 519 EFEGKQLVDITKD-FXXXXXXXXXXXXXXXXXXXXPLTTALKEILGDQVEKVVVSHKLLD 577
EFEGK+LV TK+ L +K++LGD+VEKV+VS +++D
Sbjct: 506 EFEGKKLVSATKEGLKLDETEDEKKKKEELKEKFEGLCKVIKDVLGDKVEKVIVSDRVVD 565
Query: 578 APAAIRTGQFGWSANMERIMKAQALRDSSMSSYMASKKIFEISPKSPIIRELKNKVEEGG 637
+P + TG++GW+ANMERIMKAQALRDSSM YM+SKK EI+P++ I+ EL+ + +
Sbjct: 566 SPCCLVTGEYGWTANMERIMKAQALRDSSMGGYMSSKKTMEINPENSIMDELRKRA-DAD 624
Query: 638 AQDKTVKDLTNLLFETALLTSGFSLEEPSSFASRINRLISLGLNID 683
DK+VKDL LLFETALLTSGFSL+EP++F SRI+R++ LGL+ID
Sbjct: 625 KNDKSVKDLVLLLFETALLTSGFSLDEPNTFGSRIHRMLKLGLSID 670
Score = 305 bits (781), Expect = 2e-82
Identities = 150/210 (71%), Positives = 178/210 (84%)
Query: 1 MVNQETYEFQAEITQLMSLIINTVYSNKEIFLRELISNASDALDKIRYQSLSDPKVLETE 60
M + ET+ FQAEI QL+SLIINT YSNKEIFLRELISN+SDALDKIR++SL+D L+ +
Sbjct: 1 MADAETFAFQAEINQLLSLIINTFYSNKEIFLRELISNSSDALDKIRFESLTDKSKLDGQ 60
Query: 61 PELFIRITPRPEEKVLEIRDSGIGMTKAELINNLGTIAKSGTKAFMEALSAGADVSMIGQ 120
PELFI I P L I DSGIGMTKA+L+NNLGTIA+SGTK FMEAL+AGADVSMIGQ
Sbjct: 61 PELFIHIIPDKTNNTLTIIDSGIGMTKADLVNNLGTIARSGTKEFMEALAAGADVSMIGQ 120
Query: 121 FGVGFYSLFLVADRVQVISKHNDDEQYIWESNAGGSFTVTLDESNERIGRGTVLRLFLKE 180
FGVGFYS +LVAD+V V +KHNDDEQY+WES AGGSFTVT D S E +GRGT + L+LKE
Sbjct: 121 FGVGFYSAYLVADKVVVTTKHNDDEQYVWESQAGGSFTVTRDTSGEALGRGTKMVLYLKE 180
Query: 181 DQLEYLEEKRIKDVVKKHSEFVAYPIQLLV 210
DQ+EY+EE+R+KD+VKKHSEF++YPI L +
Sbjct: 181 DQMEYIEERRLKDLVKKHSEFISYPISLWI 210
>At5g56000 [O] KOG0019 Molecular chaperone (HSP90 family)
Length = 699
Score = 480 bits (1236), Expect = e-135
Identities = 244/406 (60%), Positives = 305/406 (75%), Gaps = 2/406 (0%)
Query: 279 PLWTKNPSEVTQEEYNAFYKSISNDWEDPLAVKHFSVEGQLEFKAILFVPKRAAFDLFES 338
P+W + P E+ +EEY AFYKS+SNDWE+ LAVKHFSVEGQLEFKAILFVPKRA FDLF++
Sbjct: 266 PIWMRKPEEINKEEYAAFYKSLSNDWEEHLAVKHFSVEGQLEFKAILFVPKRAPFDLFDT 325
Query: 339 KKKKTNIKLYVRRVFITDEAEELIPEWLSFVKGVVDSEDLPLNLSREMLQQXXXXXXXXX 398
KKK NIKLYVRRVFI D E++IP++L FVKG+VDSEDLPLN+SRE LQQ
Sbjct: 326 KKKPNNIKLYVRRVFIMDNCEDIIPDYLGFVKGIVDSEDLPLNISRETLQQNKILKVIRK 385
Query: 399 XXXXXXXETFNEIAEDSEQFDKFYTAFSKNIKLGIHEDTQNRAALAKLLRYNSTKSVDEL 458
E F EIAE+ E ++KFY AFSKN+KLGIHED+QNR +A+LLRY+STKS DEL
Sbjct: 386 NLVKKCLELFFEIAENKEDYNKFYEAFSKNLKLGIHEDSQNRTKIAELLRYHSTKSGDEL 445
Query: 459 TSLSDYVTRMPEHQKNIYFITGESIKAVEKSPFLDALKAKNFEVLFLVDPIDEYAFSQLK 518
TSL DYVTRM E Q I++ITGES KAVE SPFL+ LK K +EVL++VD IDEYA QLK
Sbjct: 446 TSLKDYVTRMKEGQNEIFYITGESKKAVENSPFLEKLKKKGYEVLYMVDAIDEYAIGQLK 505
Query: 519 EFEGKQLVDITKD-FXXXXXXXXXXXXXXXXXXXXPLTTALKEILGDQVEKVVVSHKLLD 577
EFEGK+LV TK+ L +K++LGD+VEKV+VS +++D
Sbjct: 506 EFEGKKLVSATKEGLKLEETDDEKKKKEELKEKFEGLCKVIKDVLGDKVEKVIVSDRVVD 565
Query: 578 APAAIRTGQFGWSANMERIMKAQALRDSSMSSYMASKKIFEISPKSPIIRELKNKVEEGG 637
+P + TG++GW+ANMERIMKAQAL+DS+ YM+SKK EI+P++ I+ EL+ + E
Sbjct: 566 SPCCLVTGEYGWTANMERIMKAQALKDSNTGGYMSSKKTMEINPENSIMDELRKRA-EAD 624
Query: 638 AQDKTVKDLTNLLFETALLTSGFSLEEPSSFASRINRLISLGLNID 683
DK+VKDL LLFETALLTSGFSL+EP++F SRI+R++ LGL+I+
Sbjct: 625 KNDKSVKDLVLLLFETALLTSGFSLDEPNTFGSRIHRMLKLGLSIE 670
Score = 305 bits (781), Expect = 2e-82
Identities = 150/210 (71%), Positives = 178/210 (84%)
Query: 1 MVNQETYEFQAEITQLMSLIINTVYSNKEIFLRELISNASDALDKIRYQSLSDPKVLETE 60
M + ET+ FQAEI QL+SLIINT YSNKEIFLRELISN+SDALDKIR++SL+D L+ +
Sbjct: 1 MADAETFAFQAEINQLLSLIINTFYSNKEIFLRELISNSSDALDKIRFESLTDKSKLDGQ 60
Query: 61 PELFIRITPRPEEKVLEIRDSGIGMTKAELINNLGTIAKSGTKAFMEALSAGADVSMIGQ 120
PELFI I P L I DSGIGMTKA+L+NNLGTIA+SGTK FMEAL+AGADVSMIGQ
Sbjct: 61 PELFIHIIPDKTNNTLTIIDSGIGMTKADLVNNLGTIARSGTKEFMEALAAGADVSMIGQ 120
Query: 121 FGVGFYSLFLVADRVQVISKHNDDEQYIWESNAGGSFTVTLDESNERIGRGTVLRLFLKE 180
FGVGFYS +LVAD+V V +KHNDDEQY+WES AGGSFTVT D S E +GRGT + L+LKE
Sbjct: 121 FGVGFYSAYLVADKVVVTTKHNDDEQYVWESQAGGSFTVTRDTSGEALGRGTKMILYLKE 180
Query: 181 DQLEYLEEKRIKDVVKKHSEFVAYPIQLLV 210
DQ+EY+EE+R+KD+VKKHSEF++YPI L +
Sbjct: 181 DQMEYIEERRLKDLVKKHSEFISYPISLWI 210
>Hs20149594 [O] KOG0019 Molecular chaperone (HSP90 family)
Length = 724
Score = 457 bits (1176), Expect = e-128
Identities = 230/406 (56%), Positives = 296/406 (72%), Gaps = 2/406 (0%)
Query: 279 PLWTKNPSEVTQEEYNAFYKSISNDWEDPLAVKHFSVEGQLEFKAILFVPKRAAFDLFES 338
P+WT+NP ++TQEEY FYKS++NDWED LAVKHFSVEGQLEF+A+LF+P+RA FDLFE+
Sbjct: 287 PIWTRNPDDITQEEYGEFYKSLTNDWEDHLAVKHFSVEGQLEFRALLFIPRRAPFDLFEN 346
Query: 339 KKKKTNIKLYVRRVFITDEAEELIPEWLSFVKGVVDSEDLPLNLSREMLQQXXXXXXXXX 398
KKKK NIKLYVRRVFI D +ELIPE+L+F++GVVDSEDLPLN+SREMLQQ
Sbjct: 347 KKKKNNIKLYVRRVFIMDSCDELIPEYLNFIRGVVDSEDLPLNISREMLQQSKILKVIRK 406
Query: 399 XXXXXXXETFNEIAEDSEQFDKFYTAFSKNIKLGIHEDTQNRAALAKLLRYNSTKSVDEL 458
E F+E+AED E + KFY AFSKN+KLGIHED+ NR L++LLRY++++S DE+
Sbjct: 407 NIVKKCLELFSELAEDKENYKKFYEAFSKNLKLGIHEDSTNRRRLSELLRYHTSQSGDEM 466
Query: 459 TSLSDYVTRMPEHQKNIYFITGESIKAVEKSPFLDALKAKNFEVLFLVDPIDEYAFSQLK 518
TSLS+YV+RM E QK+IY+ITGES + V S F++ ++ + FEV+++ +PIDEY QLK
Sbjct: 467 TSLSEYVSRMKETQKSIYYITGESKEQVANSAFVERVRKRGFEVVYMTEPIDEYCVQQLK 526
Query: 519 EFEGKQLVDITKD-FXXXXXXXXXXXXXXXXXXXXPLTTALKEILGDQVEKVVVSHKLLD 577
EF+GK LV +TK+ L +KEIL +VEKV +S++L+
Sbjct: 527 EFDGKSLVSVTKEGLELPEDEEEKKKMEESKAKFENLCKLMKEILDKKVEKVTISNRLVS 586
Query: 578 APAAIRTGQFGWSANMERIMKAQALRDSSMSSYMASKKIFEISPKSPIIRELKNKVEEGG 637
+P I T +GW+ANMERIMKAQALRD+S YM +KK EI+P PI+ L+ K E
Sbjct: 587 SPCCIVTSTYGWTANMERIMKAQALRDNSTMGYMMAKKHLEINPDHPIVETLRQKA-EAD 645
Query: 638 AQDKTVKDLTNLLFETALLTSGFSLEEPSSFASRINRLISLGLNID 683
DK VKDL LLFETALL+SGFSLE+P + ++RI R+I LGL ID
Sbjct: 646 KNDKAVKDLVVLLFETALLSSGFSLEDPQTHSNRIYRMIKLGLGID 691
Score = 298 bits (763), Expect = 2e-80
Identities = 152/204 (74%), Positives = 174/204 (84%), Gaps = 1/204 (0%)
Query: 5 ETYEFQAEITQLMSLIINTVYSNKEIFLRELISNASDALDKIRYQSLSDPKVLETEPELF 64
ET+ FQAEI QLMSLIINT YSNKEIFLRELISNASDALDKIRY+SL+DP L++ EL
Sbjct: 13 ETFAFQAEIAQLMSLIINTFYSNKEIFLRELISNASDALDKIRYESLTDPSKLDSGKELK 72
Query: 65 IRITPRPEEKVLEIRDSGIGMTKAELINNLGTIAKSGTKAFMEALSAGADVSMIGQFGVG 124
I I P P+E+ L + D+GIGMTKA+LINNLGTIAKSGTKAFMEAL AGAD+SMIGQFGVG
Sbjct: 73 IDIIPNPQERTLTLVDTGIGMTKADLINNLGTIAKSGTKAFMEALQAGADISMIGQFGVG 132
Query: 125 FYSLFLVADRVQVISKHNDDEQYIWESNAGGSFTVTLDESNERIGRGTVLRLFLKEDQLE 184
FYS +LVA++V VI+KHNDDEQY WES+AGGSFTV D E IGRGT + L LKEDQ E
Sbjct: 133 FYSAYLVAEKVVVITKHNDDEQYAWESSAGGSFTVRADH-GEPIGRGTKVILHLKEDQTE 191
Query: 185 YLEEKRIKDVVKKHSEFVAYPIQL 208
YLEE+R+K+VVKKHS+F+ YPI L
Sbjct: 192 YLEERRVKEVVKKHSQFIGYPITL 215
>Hs13129150 [O] KOG0019 Molecular chaperone (HSP90 family)
Length = 732
Score = 451 bits (1159), Expect = e-126
Identities = 232/406 (57%), Positives = 290/406 (71%), Gaps = 2/406 (0%)
Query: 279 PLWTKNPSEVTQEEYNAFYKSISNDWEDPLAVKHFSVEGQLEFKAILFVPKRAAFDLFES 338
P+WT+NP ++T EEY FYKS++NDWED LAVKHFSVEGQLEF+A+LFVP+RA FDLFE+
Sbjct: 295 PIWTRNPDDITNEEYGEFYKSLTNDWEDHLAVKHFSVEGQLEFRALLFVPRRAPFDLFEN 354
Query: 339 KKKKTNIKLYVRRVFITDEAEELIPEWLSFVKGVVDSEDLPLNLSREMLQQXXXXXXXXX 398
+KKK NIKLYVRRVFI D EELIPE+L+F++GVVDSEDLPLN+SREMLQQ
Sbjct: 355 RKKKNNIKLYVRRVFIMDNCEELIPEYLNFIRGVVDSEDLPLNISREMLQQSKILKVIRK 414
Query: 399 XXXXXXXETFNEIAEDSEQFDKFYTAFSKNIKLGIHEDTQNRAALAKLLRYNSTKSVDEL 458
E F E+AED E + KFY FSKNIKLGIHED+QNR L++LLRY ++ S DE+
Sbjct: 415 NLVKKCLELFTELAEDKENYKKFYEQFSKNIKLGIHEDSQNRKKLSELLRYYTSASGDEM 474
Query: 459 TSLSDYVTRMPEHQKNIYFITGESIKAVEKSPFLDALKAKNFEVLFLVDPIDEYAFSQLK 518
SL DY TRM E+QK+IY+ITGE+ V S F++ L+ EV+++++PIDEY QLK
Sbjct: 475 VSLKDYCTRMKENQKHIYYITGETKDQVANSAFVERLRKHGLEVIYMIEPIDEYCVQQLK 534
Query: 519 EFEGKQLVDITKD-FXXXXXXXXXXXXXXXXXXXXPLTTALKEILGDQVEKVVVSHKLLD 577
EFEGK LV +TK+ L +K+IL +VEKVVVS++L+
Sbjct: 535 EFEGKTLVSVTKEGLELPEDEEEKKKQEEKKTKFENLCKIMKDILEKKVEKVVVSNRLVT 594
Query: 578 APAAIRTGQFGWSANMERIMKAQALRDSSMSSYMASKKIFEISPKSPIIRELKNKVEEGG 637
+P I T +GW+ANMERIMKAQALRD+S YMA+KK EI+P II L+ K E
Sbjct: 595 SPCCIVTSTYGWTANMERIMKAQALRDNSTMGYMAAKKHLEINPDHSIIETLRQKA-EAD 653
Query: 638 AQDKTVKDLTNLLFETALLTSGFSLEEPSSFASRINRLISLGLNID 683
DK+VKDL LL+ETALL+SGFSLE+P + A+RI R+I LGL ID
Sbjct: 654 KNDKSVKDLVILLYETALLSSGFSLEDPQTHANRIYRMIKLGLGID 699
Score = 295 bits (756), Expect = 1e-79
Identities = 149/206 (72%), Positives = 175/206 (84%), Gaps = 1/206 (0%)
Query: 5 ETYEFQAEITQLMSLIINTVYSNKEIFLRELISNASDALDKIRYQSLSDPKVLETEPELF 64
ET+ FQAEI QLMSLIINT YSNKEIFLRELISN+SDALDKIRY+SL+DP L++ EL
Sbjct: 18 ETFAFQAEIAQLMSLIINTFYSNKEIFLRELISNSSDALDKIRYESLTDPSKLDSGKELH 77
Query: 65 IRITPRPEEKVLEIRDSGIGMTKAELINNLGTIAKSGTKAFMEALSAGADVSMIGQFGVG 124
I + P +++ L I D+GIGMTKA+LINNLGTIAKSGTKAFMEAL AGAD+SMIGQFGVG
Sbjct: 78 INLIPNKQDRTLTIVDTGIGMTKADLINNLGTIAKSGTKAFMEALQAGADISMIGQFGVG 137
Query: 125 FYSLFLVADRVQVISKHNDDEQYIWESNAGGSFTVTLDESNERIGRGTVLRLFLKEDQLE 184
FYS +LVA++V VI+KHNDDEQY WES+AGGSFTV D + E +GRGT + L LKEDQ E
Sbjct: 138 FYSAYLVAEKVTVITKHNDDEQYAWESSAGGSFTVRTD-TGEPMGRGTKVILHLKEDQTE 196
Query: 185 YLEEKRIKDVVKKHSEFVAYPIQLLV 210
YLEE+RIK++VKKHS+F+ YPI L V
Sbjct: 197 YLEERRIKEIVKKHSQFIGYPITLFV 222
>7292327 [O] KOG0019 Molecular chaperone (HSP90 family)
Length = 717
Score = 448 bits (1153), Expect = e-125
Identities = 225/406 (55%), Positives = 289/406 (70%), Gaps = 2/406 (0%)
Query: 279 PLWTKNPSEVTQEEYNAFYKSISNDWEDPLAVKHFSVEGQLEFKAILFVPKRAAFDLFES 338
P+WT+NP +++QEEY FYKS++NDWED LAVKHFSVEGQLEF+A+LF+P+R FDLFE+
Sbjct: 280 PIWTRNPDDISQEEYGEFYKSLTNDWEDHLAVKHFSVEGQLEFRALLFIPRRTPFDLFEN 339
Query: 339 KKKKTNIKLYVRRVFITDEAEELIPEWLSFVKGVVDSEDLPLNLSREMLQQXXXXXXXXX 398
+KK+ NIKLYVRRVFI D E+LIPE+L+F+KGVVDSEDLPLN+SREMLQQ
Sbjct: 340 QKKRNNIKLYVRRVFIMDNCEDLIPEYLNFMKGVVDSEDLPLNISREMLQQNKVLKVIRK 399
Query: 399 XXXXXXXETFNEIAEDSEQFDKFYTAFSKNIKLGIHEDTQNRAALAKLLRYNSTKSVDEL 458
E E+ ED E + KFY FSKN+KLG+HED+ NRA LA LR++++ S D+
Sbjct: 400 NLVKKTMELIEELTEDKENYKKFYDQFSKNLKLGVHEDSNNRAKLADFLRFHTSASGDDF 459
Query: 459 TSLSDYVTRMPEHQKNIYFITGESIKAVEKSPFLDALKAKNFEVLFLVDPIDEYAFSQLK 518
SL+DYV+RM ++QK++YFITGES V S F++ +KA+ FEV+++ +PIDEY LK
Sbjct: 460 CSLADYVSRMKDNQKHVYFITGESKDQVSNSAFVERVKARGFEVVYMTEPIDEYVIQHLK 519
Query: 519 EFEGKQLVDITKD-FXXXXXXXXXXXXXXXXXXXXPLTTALKEILGDQVEKVVVSHKLLD 577
E++GKQLV +TK+ L +K IL ++VEKVVVS++L+D
Sbjct: 520 EYKGKQLVSVTKEGLELPEDESEKKKREEDKAKFESLCKLMKSILDNKVEKVVVSNRLVD 579
Query: 578 APAAIRTGQFGWSANMERIMKAQALRDSSMSSYMASKKIFEISPKSPIIRELKNKVEEGG 637
+P I T QFGWSANMERIMKAQALRD++ YMA KK EI+P PI+ L+ K +
Sbjct: 580 SPCCIVTSQFGWSANMERIMKAQALRDTATMGYMAGKKQLEINPDHPIVETLRQKA-DAD 638
Query: 638 AQDKTVKDLTNLLFETALLTSGFSLEEPSSFASRINRLISLGLNID 683
DK VKDL LLFET+LL+SGFSL+ P ASRI R+I LGL ID
Sbjct: 639 KNDKAVKDLVILLFETSLLSSGFSLDSPQVHASRIYRMIKLGLGID 684
Score = 293 bits (750), Expect = 6e-79
Identities = 146/206 (70%), Positives = 175/206 (84%), Gaps = 1/206 (0%)
Query: 5 ETYEFQAEITQLMSLIINTVYSNKEIFLRELISNASDALDKIRYQSLSDPKVLETEPELF 64
ET+ FQAEI QLMSLIINT YSNKEIFLRELISNASDALDKIRY+SL+DP L++ EL+
Sbjct: 6 ETFAFQAEIAQLMSLIINTFYSNKEIFLRELISNASDALDKIRYESLTDPSKLDSGKELY 65
Query: 65 IRITPRPEEKVLEIRDSGIGMTKAELINNLGTIAKSGTKAFMEALSAGADVSMIGQFGVG 124
I++ P L I D+GIGMTK++L+NNLGTIAKSGTKAFMEAL AGAD+SMIGQFGVG
Sbjct: 66 IKLIPNKTAGTLTIIDTGIGMTKSDLVNNLGTIAKSGTKAFMEALQAGADISMIGQFGVG 125
Query: 125 FYSLFLVADRVQVISKHNDDEQYIWESNAGGSFTVTLDESNERIGRGTVLRLFLKEDQLE 184
FYS +LVAD+V V SK+NDDEQY+WES+AGGSFTV D S E +GRGT + L++KEDQ +
Sbjct: 126 FYSAYLVADKVTVTSKNNDDEQYVWESSAGGSFTVRADNS-EPLGRGTKIVLYIKEDQTD 184
Query: 185 YLEEKRIKDVVKKHSEFVAYPIQLLV 210
YLEE +IK++V KHS+F+ YPI+LLV
Sbjct: 185 YLEESKIKEIVNKHSQFIGYPIKLLV 210
>CE05441 [O] KOG0019 Molecular chaperone (HSP90 family)
Length = 702
Score = 441 bits (1133), Expect = e-123
Identities = 231/405 (57%), Positives = 289/405 (71%), Gaps = 3/405 (0%)
Query: 279 PLWTKNPSEVTQEEYNAFYKSISNDWEDPLAVKHFSVEGQLEFKAILFVPKRAAFDLFES 338
P+WT+NP +++ EEY FYKS+SNDWED LAVKHFSVEGQLEF+A+LFVP+RA FDLFE+
Sbjct: 266 PIWTRNPDDISNEEYAEFYKSLSNDWEDHLAVKHFSVEGQLEFRALLFVPQRAPFDLFEN 325
Query: 339 KKKKTNIKLYVRRVFITDEAEELIPEWLSFVKGVVDSEDLPLNLSREMLQQXXXXXXXXX 398
KK K +IKLYVRRVFI + EEL+PE+L+F+KGVVDSEDLPLN+SREMLQQ
Sbjct: 326 KKSKNSIKLYVRRVFIMENCEELMPEYLNFIKGVVDSEDLPLNISREMLQQSKILKVIRK 385
Query: 399 XXXXXXXETFNEIAEDSEQFDKFYTAFSKNIKLGIHEDTQNRAALAKLLRYNSTKSVDEL 458
E +E+AED + F KFY F KN+KLGIHED+ NR L+ LRY ST + DE
Sbjct: 386 NLVKKCMELIDEVAEDKDNFKKFYEQFGKNLKLGIHEDSTNRKKLSDFLRY-STSAGDEP 444
Query: 459 TSLSDYVTRMPEHQKNIYFITGESIKAVEKSPFLDALKAKNFEVLFLVDPIDEYAFSQLK 518
TSL +YV+RM E+Q IY+ITGES V S F++ +K++ FEVL++ DPIDEY QLK
Sbjct: 445 TSLKEYVSRMKENQTQIYYITGESKDVVAASAFVERVKSRGFEVLYMCDPIDEYCVQQLK 504
Query: 519 EFEGKQLVDITKD-FXXXXXXXXXXXXXXXXXXXXPLTTALKEILGDQVEKVVVSHKLLD 577
E++GK+LV +TK+ L +K+IL +VEKV VS++L+
Sbjct: 505 EYDGKKLVSVTKEGLELPETEEEKKKFEEDKVAYENLCKVIKDILEKKVEKVGVSNRLVS 564
Query: 578 APAAIRTGQFGWSANMERIMKAQALRDSSMSSYMASKKIFEISPKSPIIRELKNKVEEGG 637
+P I T ++GWSANMERIMKAQALRDSS YMA+KK EI+P I++ L+++VE
Sbjct: 565 SPCCIVTSEYGWSANMERIMKAQALRDSSTMGYMAAKKHLEINPDHAIMKTLRDRVEV-D 623
Query: 638 AQDKTVKDLTNLLFETALLTSGFSLEEPSSFASRINRLISLGLNI 682
DKTVKDL LLFETALL SGFSLEEP S ASRI R+I LGL+I
Sbjct: 624 KNDKTVKDLVVLLFETALLASGFSLEEPQSHASRIYRMIKLGLDI 668
Score = 291 bits (745), Expect = 2e-78
Identities = 145/208 (69%), Positives = 177/208 (84%), Gaps = 1/208 (0%)
Query: 3 NQETYEFQAEITQLMSLIINTVYSNKEIFLRELISNASDALDKIRYQSLSDPKVLETEPE 62
N ET+ FQAEI QLMSLIINT YSNKEI+LRELISNASDALDKIRYQ+L++P L+T E
Sbjct: 4 NAETFAFQAEIAQLMSLIINTFYSNKEIYLRELISNASDALDKIRYQALTEPSELDTGKE 63
Query: 63 LFIRITPRPEEKVLEIRDSGIGMTKAELINNLGTIAKSGTKAFMEALSAGADVSMIGQFG 122
LFI+ITP EEK L I D+GIGMTKA+L+NNLGTIAKSGTKAFMEAL AGAD+SMIGQFG
Sbjct: 64 LFIKITPNKEEKTLTIMDTGIGMTKADLVNNLGTIAKSGTKAFMEALQAGADISMIGQFG 123
Query: 123 VGFYSLFLVADRVQVISKHNDDEQYIWESNAGGSFTVTLDESNERIGRGTVLRLFLKEDQ 182
VGFYS FLVAD+V V SK+NDD+ Y WES+AGGSF V ++ + RGT + + +KEDQ
Sbjct: 124 VGFYSAFLVADKVVVTSKNNDDDSYQWESSAGGSFVVR-PFNDPEVTRGTKIVMHIKEDQ 182
Query: 183 LEYLEEKRIKDVVKKHSEFVAYPIQLLV 210
+++LEE++IK++VKKHS+F+ YPI+L+V
Sbjct: 183 IDFLEERKIKEIVKKHSQFIGYPIKLVV 210
>At4g24190 [O] KOG0020 Endoplasmic reticulum glucose-regulated protein
(GRP94/endoplasmin) HSP90 family
Length = 823
Score = 341 bits (875), Expect = 2e-93
Identities = 181/430 (42%), Positives = 265/430 (61%), Gaps = 31/430 (7%)
Query: 280 LWTKNPSEVTQEEYNAFYKSISNDWED--PLAVKHFSVEGQLEFKAILFVPKRAAFDLFE 337
+W ++P EVT+EEY FY S+S D+ D P+A HF+ EG +EFKA+L+VP +A DL+E
Sbjct: 347 IWLRSPKEVTEEEYTKFYHSLSKDFTDEKPMAWSHFNAEGDVEFKAVLYVPPKAPHDLYE 406
Query: 338 S--KKKKTNIKLYVRRVFITDEAEELIPEWLSFVKGVVDSEDLPLNLSREMLQQXXXXXX 395
S K N+KLYVRRVFI+DE +EL+P++LSF+KG+VDS+ LPLN+SREMLQQ
Sbjct: 407 SYYNSNKANLKLYVRRVFISDEFDELLPKYLSFLKGLVDSDTLPLNVSREMLQQHSSLKT 466
Query: 396 XXXXXXXXXXETFNEIAEDSE----------------------QFDKFYTAFSKNIKLGI 433
+ ++AE+ Q+ KF+ F K++KLGI
Sbjct: 467 IKKKLIRKALDMIRKLAEEDPDEIHDDEKKDVEKSGENDEKKGQYTKFWNEFGKSVKLGI 526
Query: 434 HEDTQNRAALAKLLRYNSTKSVDELTSLSDYVTRMPEHQKNIYFITGESIKAVEKSPFLD 493
ED NR LAKLLR+ +TKS +LTSL Y+ RM + QK+I++ITG S + +EKSPFL+
Sbjct: 527 IEDAANRNRLAKLLRFETTKSDGKLTSLDQYIKRMKKSQKDIFYITGSSKEQLEKSPFLE 586
Query: 494 ALKAKNFEVLFLVDPIDEYAFSQLKEFEGKQLVDITKDFXXXXXXXXXXXXXXXXXXXXP 553
L K +EV+F DP+DEY L ++E K+ +++K+
Sbjct: 587 RLIKKGYEVIFFTDPVDEYLMQYLMDYEDKKFQNVSKE---GLKVGKDSKDKELKEAFKE 643
Query: 554 LTTALK-EILGDQVEKVVVSHKLLDAPAAIRTGQFGWSANMERIMKAQALRDSSMSSYMA 612
LT K + + V+ V +S++L D P + T +FGWSANMERIM++Q L D++ +YM
Sbjct: 644 LTKWWKGNLASENVDDVKISNRLADTPCVVVTSKFGWSANMERIMQSQTLSDANKQAYMR 703
Query: 613 SKKIFEISPKSPIIRELKNKVEEGGAQDKTVKDLTNLLFETALLTSGFSLEEPSSFASRI 672
K++ EI+P+ PII+ELK+++ +D++VK+ L+++TAL+ SGF L +P FA+RI
Sbjct: 704 GKRVLEINPRHPIIKELKDRI-ASDPEDESVKETAQLMYQTALIESGFILTDPKDFAARI 762
Query: 673 NRLISLGLNI 682
+ GLNI
Sbjct: 763 YNSVKSGLNI 772
Score = 247 bits (631), Expect = 4e-65
Identities = 123/208 (59%), Positives = 163/208 (78%), Gaps = 2/208 (0%)
Query: 3 NQETYEFQAEITQLMSLIINTVYSNKEIFLRELISNASDALDKIRYQSLSDPKVLET--E 60
N E +EFQAE+++LM +IIN++YSNK+IFLRELISNASDALDKIR+ +L+D VL
Sbjct: 75 NAEKFEFQAEVSRLMDIIINSLYSNKDIFLRELISNASDALDKIRFLALTDKDVLGEGDT 134
Query: 61 PELFIRITPRPEEKVLEIRDSGIGMTKAELINNLGTIAKSGTKAFMEALSAGADVSMIGQ 120
+L I+I +K+L IRD GIGMTK +LI NLGTIAKSGT AF+E + + D+++IGQ
Sbjct: 135 AKLEIQIKLDKAKKILSIRDRGIGMTKEDLIKNLGTIAKSGTSAFVEKMQSSGDLNLIGQ 194
Query: 121 FGVGFYSLFLVADRVQVISKHNDDEQYIWESNAGGSFTVTLDESNERIGRGTVLRLFLKE 180
FGVGFYS +LVAD ++VISKHNDD QY+WES A G F V+ D NE +GRGT +RL L++
Sbjct: 195 FGVGFYSAYLVADYIEVISKHNDDSQYVWESKANGKFAVSEDTWNEPLGRGTEIRLHLRD 254
Query: 181 DQLEYLEEKRIKDVVKKHSEFVAYPIQL 208
+ EYLEE ++K++VK++SEF+ +PI L
Sbjct: 255 EAGEYLEESKLKELVKRYSEFINFPISL 282
>Hs4507677 [O] KOG0020 Endoplasmic reticulum glucose-regulated protein
(GRP94/endoplasmin) HSP90 family
Length = 803
Score = 337 bits (864), Expect = 4e-92
Identities = 183/412 (44%), Positives = 253/412 (60%), Gaps = 9/412 (2%)
Query: 279 PLWTKNPSEVTQEEYNAFYKSISNDWEDPLAVKHFSVEGQLEFKAILFVPKRAAFDLFES 338
P+W + EV ++EY AFYKS S + +DP+A HF+ EG++ FK+ILFVP A LF+
Sbjct: 341 PIWQRPSKEVEEDEYKAFYKSFSKESDDPMAYIHFTAEGEVTFKSILFVPTSAPRGLFDE 400
Query: 339 --KKKKTNIKLYVRRVFITDEAEELIPEWLSFVKGVVDSEDLPLNLSREMLQQXXXXXXX 396
KK IKLYVRRVFITD+ +++P++L+FVKGVVDS+DLPLN+SRE LQQ
Sbjct: 401 YGSKKSDYIKLYVRRVFITDDFHDMMPKYLNFVKGVVDSDDLPLNVSRETLQQHKLLKVI 460
Query: 397 XXXXXXXXXETFNEIAEDSEQFDKFYTAFSKNIKLGIHEDTQNRAALAKLLRYNSTKSVD 456
+ +IA+D D F+ F NIKLG+ ED NR LAKLLR+ S+
Sbjct: 461 RKKLVRKTLDMIKKIADDKYN-DTFWKEFGTNIKLGVIEDHSNRTRLAKLLRFQSSHHPT 519
Query: 457 ELTSLSDYVTRMPEHQKNIYFITGESIKAVEKSPFLDALKAKNFEVLFLVDPIDEYAFSQ 516
++TSL YV RM E Q IYF+ G S K E SPF++ L K +EV++L +P+DEY
Sbjct: 520 DITSLDQYVERMKEKQDKIYFMAGSSRKEAESSPFVERLLKKGYEVIYLTEPVDEYCIQA 579
Query: 517 LKEFEGKQLVDITKD-FXXXXXXXXXXXXXXXXXXXXPLTTALKE-ILGDQVEKVVVSHK 574
L EF+GK+ ++ K+ PL +K+ L D++EK VVS +
Sbjct: 580 LPEFDGKRFQNVAKEGVKFDESEKTKESREAVEKEFEPLLNWMKDKALKDKIEKAVVSQR 639
Query: 575 LLDAPAAIRTGQFGWSANMERIMKAQAL---RDSSMSSYMASKKIFEISPKSPIIRELKN 631
L ++P A+ Q+GWS NMERIMKAQA +D S + Y + KK FEI+P+ P+IR++
Sbjct: 640 LTESPCALVASQYGWSGNMERIMKAQAYQTGKDISTNYYASQKKTFEINPRHPLIRDMLR 699
Query: 632 KVEEGGAQDKTVKDLTNLLFETALLTSGFSLEEPSSFASRINRLISLGLNID 683
+++E DKTV DL +LFETA L SG+ L + ++ RI R++ L LNID
Sbjct: 700 RIKE-DEDDKTVLDLAVVLFETATLRSGYLLPDTKAYGDRIERMLRLSLNID 750
Score = 212 bits (540), Expect = 1e-54
Identities = 113/207 (54%), Positives = 147/207 (70%), Gaps = 6/207 (2%)
Query: 5 ETYEFQAEITQLMSLIINTVYSNKEIFLRELISNASDALDKIRYQSLSDPKVLETEPELF 64
E + FQAE+ ++M LIIN++Y NKEIFLRELISNASDALDKIR SL+D L EL
Sbjct: 74 EKFAFQAEVNRMMKLIINSLYKNKEIFLRELISNASDALDKIRLISLTDENALSGNEELT 133
Query: 65 IRITPRPEEKVLEIRDSGIGMTKAELINNLGTIAKSGTKAFM----EALSAGADVS-MIG 119
++I E+ +L + D+G+GMT+ EL+ NLGTIAKSGT F+ EA G S +IG
Sbjct: 134 VKIKCDKEKNLLHVTDTGVGMTREELVKNLGTIAKSGTSEFLNKMTEAQEDGQSTSELIG 193
Query: 120 QFGVGFYSLFLVADRVQVISKHNDDEQYIWESNAGGSFTVTLDESNERIGRGTVLRLFLK 179
QFGVGFYS FLVAD+V V SKHN+D Q+IWES++ F+V D +GRGT + L LK
Sbjct: 194 QFGVGFYSAFLVADKVIVTSKHNNDTQHIWESDS-NEFSVIADPRGNTLGRGTTITLVLK 252
Query: 180 EDQLEYLEEKRIKDVVKKHSEFVAYPI 206
E+ +YLE IK++VKK+S+F+ +PI
Sbjct: 253 EEASDYLELDTIKNLVKKYSQFINFPI 279
>CE06362 [O] KOG0020 Endoplasmic reticulum glucose-regulated protein
(GRP94/endoplasmin) HSP90 family
Length = 760
Score = 331 bits (848), Expect = 3e-90
Identities = 178/410 (43%), Positives = 254/410 (61%), Gaps = 9/410 (2%)
Query: 279 PLWTKNPSEVTQEEYNAFYKSISNDWEDPLAVKHFSVEGQLEFKAILFVPKRAAFDLFES 338
P+W + P++V ++EY FYKSI+ D E+PL+ HFS EG++ F++IL+VPK++ D+F++
Sbjct: 320 PIWMRKPNQVEEDEYKQFYKSITKDSEEPLSHVHFSAEGEVSFRSILYVPKKSPNDMFQN 379
Query: 339 KKKKT-NIKLYVRRVFITDEAEELIPEWLSFVKGVVDSEDLPLNLSREMLQQXXXXXXXX 397
K NIKLYVRRVFITD+ +++P++LSF++G+VDS+DLPLN+SRE LQQ
Sbjct: 380 YGKVIENIKLYVRRVFITDDFADMLPKYLSFIRGIVDSDDLPLNVSRENLQQHKLLKVIK 439
Query: 398 XXXXXXXXETFNEIAEDSEQFDKFYTAFSKNIKLGIHEDTQNRAALAKLLRYNSTKSVDE 457
+ ++ D QFD F++ FS NIKLG+ ED NR LAKLLR+ S+ D+
Sbjct: 440 KKLVRKVLDMLKKL--DGAQFDDFWSEFSTNIKLGVMEDPSNRMRLAKLLRFQSSNDADK 497
Query: 458 LTSLSDYVTRMPEHQKNIYFITGESIKAVEKSPFLDALKAKNFEVLFLVDPIDEYAFSQL 517
T+L+ YV RM E Q IY++ G S K VE SPF++ L AK +EVLFL + +DEY +
Sbjct: 498 TTTLAAYVERMKEKQDAIYYMAGTSRKEVETSPFVERLIAKGYEVLFLTEAVDEYCIQAM 557
Query: 518 KEFEGKQLVDITKD-FXXXXXXXXXXXXXXXXXXXXPLTTALKE-ILGDQVEKVVVSHKL 575
E+E K+ ++ K+ PLT LKE L D +EK VVS +L
Sbjct: 558 PEYESKKFQNVAKEGVTIDDGEKAKEAHKGLEEEFKPLTDWLKETALKDLIEKAVVSQRL 617
Query: 576 LDAPAAIRTGQFGWSANMERIMKAQA---LRDSSMSSYMASKKIFEISPKSPIIRELKNK 632
+ +P+A+ +GWS NMERIMK+QA +D + Y KK FEI+P+ P+I+EL +
Sbjct: 618 VKSPSALVASSYGWSGNMERIMKSQAYAKAKDPTQDFYATQKKTFEINPRHPVIKELLKR 677
Query: 633 VEEGGAQDKTVKDLTNLLFETALLTSGFSLEEPSSFASRINRLISLGLNI 682
V +D T LLFETA L SGFSL++ FA RI ++ L++
Sbjct: 678 V-TASEEDTTAASTAKLLFETATLRSGFSLQDQVGFADRIEAVLRQSLDV 726
Score = 214 bits (545), Expect = 4e-55
Identities = 110/209 (52%), Positives = 152/209 (72%), Gaps = 6/209 (2%)
Query: 5 ETYEFQAEITQLMSLIINTVYSNKEIFLRELISNASDALDKIRYQSLSDPKVLETEPELF 64
E +EFQAE+ ++M LIIN++Y NKEIFLRELISNASDALDKIR SL+DP+ L E+
Sbjct: 62 EKHEFQAEVNRMMKLIINSLYRNKEIFLRELISNASDALDKIRLLSLTDPEQLRETEEMS 121
Query: 65 IRITPRPEEKVLEIRDSGIGMTKAELINNLGTIAKSGTKAFME-----ALSAGADVSMIG 119
++I E ++L I D+G+GMT+ +LINNLGTIA+SGT F+ A S+ +IG
Sbjct: 122 VKIKADRENRLLHITDTGVGMTRQDLINNLGTIARSGTSEFLSKLMDTATSSDQQQDLIG 181
Query: 120 QFGVGFYSLFLVADRVQVISKHNDDEQYIWESNAGGSFTVTLDESNERIGRGTVLRLFLK 179
QFGVGFY+ FLVADRV V +K+NDD+QYIWES++ SFT++ D + RGT + L+LK
Sbjct: 182 QFGVGFYAAFLVADRVVVTTKNNDDDQYIWESDS-ASFTISKDPRGNTLKRGTQITLYLK 240
Query: 180 EDQLEYLEEKRIKDVVKKHSEFVAYPIQL 208
E+ ++LE +K++V K+S+F+ + I L
Sbjct: 241 EEAADFLEPDTLKNLVHKYSQFINFDIFL 269
>7301648 [O] KOG0020 Endoplasmic reticulum glucose-regulated protein
(GRP94/endoplasmin) HSP90 family
Length = 787
Score = 314 bits (805), Expect = 3e-85
Identities = 174/413 (42%), Positives = 255/413 (61%), Gaps = 12/413 (2%)
Query: 279 PLWTKNPSEVTQEEYNAFYKSISNDWEDPLAVKHFSVEGQLEFKAILFVPKRAAFDLFES 338
P+WT+ P+EVT++EY +FYKS++ D +PL HF EG++ FK++L+VPK + F
Sbjct: 341 PIWTRKPAEVTEDEYTSFYKSLTKDSSEPLTQTHFIAEGEVTFKSLLYVPKVQPSESFNR 400
Query: 339 KKKKT-NIKLYVRRVFITDEAEELIPEWLSFVKGVVDSEDLPLNLSREMLQQXXXXXXXX 397
K+ NIKLYVRRVFITDE +++P +LSF++GVVDS+DLPLN+SRE LQQ
Sbjct: 401 YGTKSDNIKLYVRRVFITDEFNDMMPNYLSFIRGVVDSDDLPLNVSRETLQQHKLIKVIK 460
Query: 398 XXXXXXXXETFNEIAEDSEQFDKFYTAFSKNIKLGIHEDTQNRAALAKLLRYNSTKSVDE 457
+ +I D E ++KF+ FS NIKLG+ ED NR+ LAKLLR+ T +
Sbjct: 461 KKLVRKVLDMLKKI--DKEAYEKFWKEFSTNIKLGVMEDPSNRSRLAKLLRF-QTSNGKG 517
Query: 458 LTSLSDYVTRMPEHQKNIYFITGESIKAVEKSPFLDALKAKNFEVLFLVDPIDEYAFSQL 517
+TSL++Y RM Q++IY+I G + VEKSPF++ L +K +EVL+LV+ +DEY S L
Sbjct: 518 VTSLAEYKERMKAKQEHIYYIAGANRAEVEKSPFVERLLSKGYEVLYLVEAVDEYCISAL 577
Query: 518 KEFEGKQLVDITKD-FXXXXXXXXXXXXXXXXXXXXPLTTALKEI-LGDQVEKVVVSHKL 575
EF+GK+ ++ K+ F PL L ++ L DQ+ K VS +L
Sbjct: 578 PEFDGKKFQNVAKEGFQLNESEKSKKNFESLKSTFEPLVKWLNDVALKDQISKAQVSERL 637
Query: 576 LDAPAAIRTGQFGWSANMERIMKAQALR---DSSMSSYMASKKIFEISPKSPIIRELKNK 632
++P A+ G FGW+ NMER+ + A + D + Y+ KK EI+P+ P++REL +
Sbjct: 638 SNSPCALVAGVFGWTGNMERLAMSNAHQKSDDPQRTYYLNQKKTLEINPRHPLMRELLRR 697
Query: 633 VEEGGAQDKTVKDLTNLLFETALLTSGFSLEEPSSFASRINRLI--SLGLNID 683
VE A D T KD+ ++F TA L SG+ L+E S FA I +++ +LG++ D
Sbjct: 698 VEADEADD-TAKDMAVMMFRTATLRSGYMLQETSQFADSIEQMMRQTLGVSQD 749
Score = 230 bits (587), Expect = 5e-60
Identities = 119/208 (57%), Positives = 158/208 (75%), Gaps = 7/208 (3%)
Query: 7 YEFQAEITQLMSLIINTVYSNKEIFLRELISNASDALDKIRYQSLSDPKVLETEPELFIR 66
+ FQ E+ ++M LIIN++Y NKEIFLRELISNASDA+DKIR +LS+ K LET PEL IR
Sbjct: 75 FTFQTEVNRMMKLIINSLYRNKEIFLRELISNASDAIDKIRLLALSNSKELETNPELHIR 134
Query: 67 ITPRPEEKVLEIRDSGIGMTKAELINNLGTIAKSGTKAFMEAL-----SAGADVS-MIGQ 120
I E K L I DSGIGMT +LINNLGTIAKSGT F+ + S G D++ MIGQ
Sbjct: 135 IKADKENKALHIMDSGIGMTHQDLINNLGTIAKSGTADFLAKMQDPSKSEGLDMNDMIGQ 194
Query: 121 FGVGFYSLFLVADRVQVISKHNDDEQYIWESNAGGSFTVTLDESNERIGRGTVLRLFLKE 180
FGVGFYS FLVADRV V +KHNDD+QYIWES+A SF++T D + + RG+V+ L+LKE
Sbjct: 195 FGVGFYSAFLVADRVVVTTKHNDDKQYIWESDA-NSFSITEDPRGDTLKRGSVISLYLKE 253
Query: 181 DQLEYLEEKRIKDVVKKHSEFVAYPIQL 208
+ ++LEE ++++++K+S+F+ +PI++
Sbjct: 254 EAQDFLEEDTVRELIRKYSQFINFPIRM 281
>At2g04030 [O] KOG0019 Molecular chaperone (HSP90 family)
Length = 780
Score = 306 bits (785), Expect = 5e-83
Identities = 165/406 (40%), Positives = 255/406 (62%), Gaps = 6/406 (1%)
Query: 279 PLWTKNPSEVTQEEYNAFYKSISNDWEDPLAVKHFSVEGQLEFKAILFVPKRAAFDLFES 338
PLW +N EV + EYN FYK N++ DPLA HF+ EG++EF++IL++P + +
Sbjct: 334 PLWMRNSKEVEKGEYNEFYKKAFNEFLDPLAHTHFTTEGEVEFRSILYIPGMGPLNNEDV 393
Query: 339 KKKKT-NIKLYVRRVFITDEAE-ELIPEWLSFVKGVVDSEDLPLNLSREMLQQXXXXXXX 396
KT NI+LYV+RVFI+D+ + EL P +LSFVKGVVDS+DLPLN+SRE+LQ+
Sbjct: 394 TNPKTKNIRLYVKRVFISDDFDGELFPRYLSFVKGVVDSDDLPLNVSREILQESRIVRIM 453
Query: 397 XXXXXXXXXETFNEIAE--DSEQFDKFYTAFSKNIKLGIHEDTQNRAALAKLLRYNSTKS 454
+ EI+E + E + KF+ F + +KLG EDT N + LLR+ S+K+
Sbjct: 454 RKRLIRKTFDMIQEISESENKEDYKKFWENFGRFLKLGCIEDTGNHKRITPLLRFFSSKN 513
Query: 455 VDELTSLSDYVTRMPEHQKNIYFITGESIKAVEKSPFLDALKAKNFEVLFLVDPIDEYAF 514
+ELTSL DY+ M E+QK IY++ +S+K+ + +PFL+ L K+ EVL+LV+PIDE A
Sbjct: 514 EEELTSLDDYIENMGENQKAIYYLATDSLKSAKSAPFLEKLIQKDIEVLYLVEPIDEVAI 573
Query: 515 SQLKEFEGKQLVDITKDFXXXXXXXXXXXXXXXXXXXXPLTTALKEILGDQVEKVVVSHK 574
L+ ++ K+ VDI+K+ L +K+ LGD+V KV VS++
Sbjct: 574 QNLQTYKEKKFVDISKE-DLELGDEDEVKDREAKQEFNLLCDWIKQQLGDKVAKVQVSNR 632
Query: 575 LLDAPAAIRTGQFGWSANMERIMKAQALRDSSMSSYMASKKIFEISPKSPIIRELKNKVE 634
L +P + +G+FGWSANMER+MKAQAL D+S +M ++I EI+P PII++L N
Sbjct: 633 LSSSPCVLVSGKFGWSANMERLMKAQALGDTSSLEFMRGRRILEINPDHPIIKDL-NAAC 691
Query: 635 EGGAQDKTVKDLTNLLFETALLTSGFSLEEPSSFASRINRLISLGL 680
+ + + +LL++TA+++SGF+ + P+ ++I ++++ +
Sbjct: 692 KNAPESTEATRVVDLLYDTAIISSGFTPDSPAELGNKIYEMMAMAV 737
Score = 198 bits (503), Expect = 3e-50
Identities = 106/210 (50%), Positives = 154/210 (72%), Gaps = 8/210 (3%)
Query: 5 ETYEFQAEITQLMSLIINTVYSNKEIFLRELISNASDALDKIRYQSLSDPKVLETEPELF 64
E +E+QAE+++L+ LI++++YS+KE+FLREL+SNASDALDK+R+ S+++P +L +L
Sbjct: 77 EKFEYQAEVSRLLDLIVHSLYSHKEVFLRELVSNASDALDKLRFLSVTEPSLLGDGGDLE 136
Query: 65 IRITPRPEEKVLEIRDSGIGMTKAELINNLGTIAKSGTKAFMEAL----SAGADVSMIGQ 120
IRI P P+ + I D+GIGMTK ELI+ LGTIA+SGT F++AL GAD +IGQ
Sbjct: 137 IRIKPDPDNGTITITDTGIGMTKEELIDCLGTIAQSGTSKFLKALKENKDLGADNGLIGQ 196
Query: 121 FGVGFYSLFLVADRVQVISKH-NDDEQYIWESNAGGSFTVTLDES--NERIGRGTVLRLF 177
FGVGFYS FLVA++V V +K D+QY+WES A S + +E+ + + RGT + L+
Sbjct: 197 FGVGFYSAFLVAEKVVVSTKSPKSDKQYVWESVADSSSYLIREETDPDNILRRGTQITLY 256
Query: 178 LKE-DQLEYLEEKRIKDVVKKHSEFVAYPI 206
L+E D+ E+ E RIK++VK +S+FV +PI
Sbjct: 257 LREDDKYEFAESTRIKNLVKNYSQFVGFPI 286
>At3g07770 [O] KOG0019 Molecular chaperone (HSP90 family)
Length = 803
Score = 293 bits (751), Expect = 5e-79
Identities = 159/410 (38%), Positives = 244/410 (58%), Gaps = 8/410 (1%)
Query: 279 PLWTKNPSEVTQEEYNAFYKSISNDWEDPLAVKHFSVEGQLEFKAILFVPKRAAFDLFES 338
P+W +NP EVT EYN FY+ N++ DPLA HF+ EG++EF++IL+VP + +
Sbjct: 357 PIWLRNPKEVTTAEYNEFYRKAFNEYLDPLASSHFTTEGEVEFRSILYVPPVSPSGKDDI 416
Query: 339 KKKKT-NIKLYVRRVFITDEAE-ELIPEWLSFVKGVVDSEDLPLNLSREMLQQXXXXXXX 396
+KT NI+LYV+RVFI+D+ + EL P +LSFVKGVVDS DLPLN+SRE+LQ+
Sbjct: 417 VNQKTKNIRLYVKRVFISDDFDGELFPRYLSFVKGVVDSHDLPLNVSREILQESRIVRIM 476
Query: 397 XXXXXXXXXETFNEIA--EDSEQFDKFYTAFSKNIKLGIHEDTQNRAALAKLLRYNSTKS 454
+ I+ E+ E ++KF+ F K++KLG ED +N +A LLR+ S++S
Sbjct: 477 KKRLVRKAFDMILGISLSENREDYEKFWDNFGKHLKLGCIEDRENHKRIAPLLRFFSSQS 536
Query: 455 VDELTSLSDYVTRMPEHQKNIYFITGESIKAVEKSPFLDALKAKNFEVLFLVDPIDEYAF 514
+++ SL +YV M QK IYFI +SI + + +PFL+ + K EVL+LV+PIDE A
Sbjct: 537 ENDMISLDEYVENMKPEQKAIYFIASDSITSAKNAPFLEKMLEKGLEVLYLVEPIDEVAV 596
Query: 515 SQLKEFEGKQLVDITK---DFXXXXXXXXXXXXXXXXXXXXPLTTALKEILGDQVEKVVV 571
LK ++ K VDI+K D +K+ LGD+V V +
Sbjct: 597 QSLKAYKEKDFVDISKEDLDLGNMSGDKNEEKEAAVKKEFGQTCDWIKKRLGDKVASVQI 656
Query: 572 SHKLLDAPAAIRTGQFGWSANMERIMKAQALRDSSMSSYMASKKIFEISPKSPIIRELKN 631
S++L +P + +G+FGWSANMER+MKAQ+ D+ YM +++FEI+P II+ + N
Sbjct: 657 SNRLSSSPCVLVSGKFGWSANMERLMKAQSTGDTISLDYMKGRRVFEINPDHSIIKNI-N 715
Query: 632 KVEEGGAQDKTVKDLTNLLFETALLTSGFSLEEPSSFASRINRLISLGLN 681
D+ +L+++ AL++SGF+ + P+ +I ++ + L+
Sbjct: 716 AAYNSNPNDEDAMRAIDLMYDAALVSSGFTPDNPAELGGKIYEMMDVALS 765
Score = 204 bits (518), Expect = 5e-52
Identities = 109/209 (52%), Positives = 153/209 (73%), Gaps = 7/209 (3%)
Query: 5 ETYEFQAEITQLMSLIINTVYSNKEIFLRELISNASDALDKIRYQSLSDPKVLETEPELF 64
E +E+QAE+++LM LI+N++YSNKE+FLRELISNASDALDK+RY S+++P++ + P+L
Sbjct: 95 EKFEYQAEVSRLMDLIVNSLYSNKEVFLRELISNASDALDKLRYLSVTNPELSKDAPDLD 154
Query: 65 IRITPRPEEKVLEIRDSGIGMTKAELINNLGTIAKSGTKAFMEAL----SAGADVSMIGQ 120
IRI E ++ + DSGIGMT+ EL++ LGTIA+SGT FM+AL AG D ++IGQ
Sbjct: 155 IRIYADKENGIITLTDSGIGMTRQELVDCLGTIAQSGTAKFMKALKDSKDAGGDNNLIGQ 214
Query: 121 FGVGFYSLFLVADRVQVISKH-NDDEQYIWESNA-GGSFTVTLD-ESNERIGRGTVLRLF 177
FGVGFYS FLVADRV V +K D+QY+WE A SFT+ D + I RGT + L
Sbjct: 215 FGVGFYSAFLVADRVIVSTKSPKSDKQYVWEGEANSSSFTIQEDTDPQSLIPRGTRITLH 274
Query: 178 LKEDQLEYLEEKRIKDVVKKHSEFVAYPI 206
LK++ + + +RI+ +VK +S+FV++PI
Sbjct: 275 LKQEAKNFADPERIQKLVKNYSQFVSFPI 303
>Hs22065017 [O] KOG0019 Molecular chaperone (HSP90 family)
Length = 343
Score = 290 bits (741), Expect = 7e-78
Identities = 147/206 (71%), Positives = 173/206 (83%), Gaps = 1/206 (0%)
Query: 5 ETYEFQAEITQLMSLIINTVYSNKEIFLRELISNASDALDKIRYQSLSDPKVLETEPELF 64
ET+ FQAEI QLMSLIINT YSNKEIFLRELISN+SDALDKI Y+SL+DP L++ EL
Sbjct: 18 ETFAFQAEIAQLMSLIINTFYSNKEIFLRELISNSSDALDKIWYESLTDPSKLDSGKELH 77
Query: 65 IRITPRPEEKVLEIRDSGIGMTKAELINNLGTIAKSGTKAFMEALSAGADVSMIGQFGVG 124
I + P +++ L I D+GIGMTKA+LINNLGTIAKSGTKAFMEAL AGAD+SMIGQFGV
Sbjct: 78 INLIPNKQDQTLTIVDTGIGMTKADLINNLGTIAKSGTKAFMEALQAGADISMIGQFGVS 137
Query: 125 FYSLFLVADRVQVISKHNDDEQYIWESNAGGSFTVTLDESNERIGRGTVLRLFLKEDQLE 184
FYS +LVA++V VI+KHNDDEQY WES+AGGSFTV D + ER+GRGT + L LKEDQ E
Sbjct: 138 FYSAYLVAEKVTVITKHNDDEQYAWESSAGGSFTVRTD-TGERMGRGTKVILHLKEDQTE 196
Query: 185 YLEEKRIKDVVKKHSEFVAYPIQLLV 210
YLEE+RIK++VKKHS+ + YPI L V
Sbjct: 197 YLEEQRIKEIVKKHSQLIGYPITLFV 222
Score = 89.0 bits (219), Expect = 2e-17
Identities = 36/50 (72%), Positives = 45/50 (90%)
Query: 279 PLWTKNPSEVTQEEYNAFYKSISNDWEDPLAVKHFSVEGQLEFKAILFVP 328
P+WT+NP ++T EEY FYK+++NDWED LAVKHFSVEGQLEF+A+LFVP
Sbjct: 294 PIWTRNPDDITNEEYGEFYKNLTNDWEDHLAVKHFSVEGQLEFRALLFVP 343
>ECU02g1100 [O] KOG0019 Molecular chaperone (HSP90 family)
Length = 690
Score = 263 bits (671), Expect = 9e-70
Identities = 145/397 (36%), Positives = 226/397 (56%), Gaps = 9/397 (2%)
Query: 279 PLWTKNPSEVTQEEYNAFYKSISNDWEDPLAVKHFSVEGQLEFKAILFVPKRAAFDLFES 338
PLW +N EV +EE +FYK++S DW+D LAV + +EG L + ++F+PKRA FD+F
Sbjct: 281 PLWKRNIKEVPEEELKSFYKTVSGDWDDFLAVDFWHIEGLLSIELLMFIPKRARFDMFNK 340
Query: 339 KKKKTNIKLYVRRVFITDEAEELIPEWLSFVKGVVDSEDLPLNLSREMLQQXXXXXXXXX 398
KK NIKLY + VF+TD+ + IPEW+SFV GVV S+D+P+N+SREM+Q
Sbjct: 341 NKKNNNIKLYCKNVFVTDDFGDAIPEWMSFVSGVVASDDIPMNISREMIQGTNVMKLVKK 400
Query: 399 XXXXXXXETFNEIAEDSEQFDKFYTAFSKNIKLGIHEDTQNRA-ALAKLLRYNSTKSVDE 457
E ++A D+E++ FY F +K+ I E ++ + AK LRY +TKS +E
Sbjct: 401 TLPQKIFEMIGKLALDAEKYKTFYKEFGNCLKMAIGEASEGQQDGYAKCLRYFTTKSGEE 460
Query: 458 LTSLSDYVTRMPEHQKNIYFITGESIKAVEKSPFLDALKAKNFEVLFLVDPIDEYAFSQL 517
SL YV RM +QK IY ITG S + V+ +P LDA + +EV+++ + +DE L
Sbjct: 461 AISLDTYVERMAPNQKQIYVITGLSKEQVKSNPALDAF--QKYEVIYMHEVMDEVMLRGL 518
Query: 518 KEFEGKQLVDITKDFXXXXXXXXXXXXXXXXXXXXPLTTALKEILGDQVEKVVVSHKLLD 577
K+++G + IT + +K+IL +VEKV V+ +L+
Sbjct: 519 KKYKGHTIQRITSE--GVELPEDEASNEEVVKSFEEFCKKVKDILSSKVEKVTVNPRLVS 576
Query: 578 APAAIRTGQFGWSANMERIMKAQALRDSSMSSYM--ASKKIFEISPKSPIIRELKNKVEE 635
PA I T ++ S ME IMK+Q + +++ + M SKKIFE++P +++ LK +
Sbjct: 577 VPAVISTTKYSLSGTMENIMKSQPVTEANPFAAMTAVSKKIFEMNPNHQLVKNLKALFDS 636
Query: 636 GGAQDKTVKDLTNLLFETALLTSGFSLEEPSSFASRI 672
+ + + + + FET L+ +GF L +P F + +
Sbjct: 637 N--EIEKMNRILEVFFETVLIHNGFVLSDPKGFCANV 671
Score = 180 bits (456), Expect = 8e-45
Identities = 98/215 (45%), Positives = 140/215 (64%), Gaps = 8/215 (3%)
Query: 3 NQETYEFQAEITQLMSLIINTVYSNKEIFLRELISNASDALDKIR---YQSLSDPKVLET 59
+ ET+ F+ ++ Q+M +I +VYS+KE+FLREL+SN+SDA DK++ +Q VL+
Sbjct: 17 HSETHGFEVDVNQMMDTMIKSVYSSKELFLRELVSNSSDACDKLKALYFQLREKGCVLDP 76
Query: 60 EPELFIRITPRPEEKVLEIRDSGIGMTKAELINNLGTIAKSGTKAFMEALSA---GADVS 116
L I I P + + L I+D+GIGMTK +L+N +GTIA SGTK F E + AD S
Sbjct: 77 VTSLGIEIIPNKDNRTLTIKDNGIGMTKPDLMNFIGTIASSGTKKFREEMKEKGNSADAS 136
Query: 117 -MIGQFGVGFYSLFLVADRVQVISKHNDDEQYIWESNAGGSFTVTLDESNERIGRGTVLR 175
+IGQFG+GFYS +LVA+RV +I+KH DE +W S +T+ + E GT L
Sbjct: 137 NLIGQFGLGFYSSYLVAERVDLITKHPSDEALVWTSTGRDVYTIE-EYDGEPFAHGTSLV 195
Query: 176 LFLKEDQLEYLEEKRIKDVVKKHSEFVAYPIQLLV 210
L++KE + E+L+ KRI ++VKK+S FV YPI V
Sbjct: 196 LYIKEGEEEFLDPKRISEIVKKYSLFVFYPIYTYV 230
>Hs22043581 [O] KOG0020 Endoplasmic reticulum glucose-regulated protein
(GRP94/endoplasmin) HSP90 family
Length = 329
Score = 221 bits (563), Expect = 3e-57
Identities = 132/330 (40%), Positives = 187/330 (56%), Gaps = 10/330 (3%)
Query: 308 LAVKHFSVEGQLEFKAILFVPK---RAAFDLFESKKKKTNIKLYVRRVFITDEAEELIPE 364
+A HF+ EG++ FK+ILFVP R FD + SKK IKLYV VFITDE +++P+
Sbjct: 1 MAYIHFTTEGEVTFKSILFVPTSDPRGLFDEYGSKKSDY-IKLYVLCVFITDEFHDMMPK 59
Query: 365 WLSFVKGVVDSEDLPLNLSREMLQQXXXXXXXXXXXXXXXXETFNEIAEDSEQFDKFYTA 424
+L+FVKGVVDS+DLPLN+S E LQQ + +IA + D F+
Sbjct: 60 YLNFVKGVVDSDDLPLNVSLETLQQHKLLKVIRKKLVCKTLDKIKKIAGEKYN-DNFWKE 118
Query: 425 FSKNIKLGIHEDTQNRAALAKLLRYNSTKSVDELTSLSDYVTRMPEHQKNIYFITGESIK 484
F NIKLG+ ED N+ LAKLL + S+ ++T+L YV RM Q IYF+ G S K
Sbjct: 119 FGTNIKLGVIEDHSNQTCLAKLLMFQSSHHPTDITTLDQYVERMKGKQDKIYFMAGSSRK 178
Query: 485 AVEKSPFLDALKAKNFEVLFLVDPIDEYAFSQLKEFEGKQLVDITKD-FXXXXXXXXXXX 543
E P ++ L K EV++L +P+DE+ +F+GK+ ++ K+
Sbjct: 179 EAESPPSVERLLKKGCEVIYLTEPVDEHCIQAFPKFDGKRFQNVVKEGMKFDKSEKTKES 238
Query: 544 XXXXXXXXXPLTTALKE-ILGDQVEKVVVSHKLLDAPAAIRTGQFGWSANMERIMKAQAL 602
PL +K+ L D++EK VVS L ++ A+ Q+G S N ERIMKAQA
Sbjct: 239 HEAVEKEFEPLLNWMKDKALKDKIEKAVVSQHLTESLCALVASQYGRSGNTERIMKAQAY 298
Query: 603 ---RDSSMSSYMASKKIFEISPKSPIIREL 629
+DSS + Y + KK FEI+P+ P+IR++
Sbjct: 299 QTSKDSSANYYASQKKTFEINPRHPLIRDM 328
>7302271 [O] KOG0019 Molecular chaperone (HSP90 family)
Length = 691
Score = 190 bits (482), Expect = 7e-48
Identities = 130/413 (31%), Positives = 204/413 (48%), Gaps = 20/413 (4%)
Query: 279 PLWTKNPSEVTQEEYNAFYKSISNDWEDPLAVKHFSVEGQLEFKAILFVPKRAAFDLFE- 337
PLW P +++E+++ FY+ ISN ++ P H++ + L A+L+ P+ LFE
Sbjct: 285 PLWLLEPQSISKEQHHDFYRFISNSFDVPRFTLHYNADVPLSIHALLYFPEGKP-GLFEM 343
Query: 338 SKKKKTNIKLYVRRVFITDEAEELIPEWLSFVKGVVDSEDLPLNLSREMLQQXXXXXXXX 397
S+ T + LY R+V I + E L+P+WL FVKGVVDSED+PLNLSRE+LQ
Sbjct: 344 SRDGNTGVALYTRKVLIQSKTEHLLPKWLRFVKGVVDSEDIPLNLSRELLQNSSLIRKLS 403
Query: 398 XXXXXXXXETFNEIA-EDSEQFDKFYTAFSKNIKLGI--HEDTQNRAALAKLLRYNSTKS 454
E + + E+++ FY + +K GI D + +AKLLR+ S+KS
Sbjct: 404 SVISTRVIRFLQERSKKQPEEYEAFYRDYGLFLKEGIVTSSDASEKEEIAKLLRFESSKS 463
Query: 455 --VDELTSLSDYVTRMPEHQKNIYFITGESIKAVEKSPFLDALKAKNFEVLFLVDPIDEY 512
SL +Y +P Q+NIY++ + E SP+ ++LK +N VLF +P DE
Sbjct: 464 ETASGRMSLEEYYNAVPAEQQNIYYLAAPNRVLAESSPYYESLKKRNELVLFCYEPYDEL 523
Query: 513 AFSQLKEFEGKQLVDITKDFXXXXXXXXXXX----XXXXXXXXXPLTTALKEILGDQVEK 568
QL +F+ K+LV + K+ L L+E L QV K
Sbjct: 524 VLMQLGKFKSKKLVSVEKEMREESKETTATTDFGEGSLLRSELDTLIPWLEEELRGQVIK 583
Query: 569 VVVSHKLLDAPAAIRTGQFGWSANMERIMKAQALRDSSMSSYMASKKIFEISPKSPIIRE 628
V + +L P I + A ++ Q+ + + + + EI+PK PII++
Sbjct: 584 VKATTRLDTHPCVITVEEM---AAARHFIRTQSHQVPEQNRFALLQPELEINPKHPIIKK 640
Query: 629 LKNKVEEGGAQDKTVKDL-TNLLFETALLTSGFSLEEPSSFASRINRLISLGL 680
L NK+ E DK + L LF A++ +G + E+P + +N L+S L
Sbjct: 641 L-NKLRE---SDKDLAQLIAKQLFANAMVGAGLA-EDPRMLLTNMNTLLSRAL 688
Score = 160 bits (405), Expect = 6e-39
Identities = 96/215 (44%), Positives = 138/215 (63%), Gaps = 14/215 (6%)
Query: 5 ETYEFQAEITQLMSLIINTVYSNKEIFLRELISNASDALDKIRYQSLS--DPKVLETEPE 62
+ +EFQAE QL+ ++ ++YS+ E+F+RELISNASDAL+K RY SLS + +
Sbjct: 64 DKHEFQAETRQLLDIVARSLYSDHEVFVRELISNASDALEKFRYTSLSAGGENLAGKDRP 123
Query: 63 LFIRITPRPEEKVLEIRDSGIGMTKAELINNLGTIAKSGTKAFMEAL-------SAGADV 115
L IRIT L I+D+GIGMTK EL++NLGTIA+SG+K F+E + S+ A
Sbjct: 124 LEIRITTDKPLMQLIIQDTGIGMTKEELVSNLGTIARSGSKKFLEQMKGTQQGASSEASS 183
Query: 116 SMIGQFGVGFYSLFLVADRVQVISKH--NDDEQYIWESNAGGSFTVTLDESNERIGRGTV 173
++IGQFGVGFYS F+VA++V+V ++ + W ++ G++ + E + GT
Sbjct: 184 NIIGQFGVGFYSSFIVANKVEVFTRAAVPNAPGLRWSTDGSGTYEI---EEVPDVELGTR 240
Query: 174 LRLFLKEDQLEYLEEKRIKDVVKKHSEFVAYPIQL 208
+ L LK D EY +E+RIK V+KK+S FV PI L
Sbjct: 241 IVLHLKTDCREYADEERIKAVIKKYSNFVGSPILL 275
>Hs16157901 [O] KOG0019 Molecular chaperone (HSP90 family)
Length = 249
Score = 187 bits (474), Expect = 6e-47
Identities = 101/217 (46%), Positives = 137/217 (62%), Gaps = 2/217 (0%)
Query: 468 MPEHQKNIYFITGESIKAVEKSPFLDALKAKNFEVLFLVDPIDEYAFSQLKEFEGKQLVD 527
M E QK+ Y+ITGES + V S F++ ++ + FEV+++ +PIDEY QLKEF+GK LV
Sbjct: 1 MKETQKSTYYITGESKEQVANSAFVERVRKQGFEVVYMTEPIDEYCVQQLKEFDGKSLVS 60
Query: 528 ITKD-FXXXXXXXXXXXXXXXXXXXXPLTTALKEILGDQVEKVVVSHKLLDAPAAIRTGQ 586
+TK+ L +KEIL +VEKV +S++L+ +P I T
Sbjct: 61 VTKEGLELPEDEEEKKKMEESKEKFENLCKLMKEILDKKVEKVTISNRLVSSPCCIVTST 120
Query: 587 FGWSANMERIMKAQALRDSSMSSYMASKKIFEISPKSPIIRELKNKVEEGGAQDKTVKDL 646
+GW+ANME+IMKAQALRD+S YM +KK EI+P PI+ L+ K E DK VKDL
Sbjct: 121 YGWTANMEQIMKAQALRDNSTMGYMMAKKHLEINPDHPIMETLRQKA-EADKNDKAVKDL 179
Query: 647 TNLLFETALLTSGFSLEEPSSFASRINRLISLGLNID 683
LLFETALL+SGFSLE+P + ++ I +I LGL D
Sbjct: 180 VVLLFETALLSSGFSLEDPQTHSNHIYHMIKLGLGTD 216
>Hs20535880 [O] KOG0019 Molecular chaperone (HSP90 family)
Length = 340
Score = 179 bits (454), Expect = 1e-44
Identities = 93/190 (48%), Positives = 117/190 (60%), Gaps = 31/190 (16%)
Query: 279 PLWTKNPSEVTQEEYNAFYKSISNDWEDPLAVKHFSVEGQLEFKAILFVPKRAAFDLFES 338
P+WT+NP ++T EEY FYKS++NDWED L
Sbjct: 175 PIWTRNPDDITNEEYREFYKSLTNDWEDHL------------------------------ 204
Query: 339 KKKKTNIKLYVRRVFITDEAEELIPEWLSFVKGVVDSEDLPLNLSREMLQQXXXXXXXXX 398
KKK NIKLYV RVFITD EELIPE+L+F++ +VDSEDLPLN+S +MLQQ
Sbjct: 205 -KKKNNIKLYVCRVFITDNCEELIPEYLNFIRVLVDSEDLPLNISHKMLQQSKILKVIRK 263
Query: 399 XXXXXXXETFNEIAEDSEQFDKFYTAFSKNIKLGIHEDTQNRAALAKLLRYNSTKSVDEL 458
E F E+AED E + KFY FS+NIKLGIHED+QN+ L++LLRY ++ S DE+
Sbjct: 264 NLVKKCLELFTELAEDKENYKKFYEQFSENIKLGIHEDSQNQKKLSELLRYYTSASGDEM 323
Query: 459 TSLSDYVTRM 468
SL DY TR+
Sbjct: 324 VSLKDYCTRI 333
>Hs7706485 [O] KOG0019 Molecular chaperone (HSP90 family)
Length = 704
Score = 174 bits (442), Expect = 3e-43
Identities = 95/206 (46%), Positives = 140/206 (67%), Gaps = 10/206 (4%)
Query: 7 YEFQAEITQLMSLIINTVYSNKEIFLRELISNASDALDKIRYQSLSDPKVLETEPELFIR 66
+EFQAE +L+ ++ ++YS KE+F+RELISNASDAL+K+R++ +SD + L PE+ I
Sbjct: 88 HEFQAETKKLLDIVARSLYSEKEVFIRELISNASDALEKLRHKLVSDGQAL---PEMEIH 144
Query: 67 ITPRPEEKVLEIRDSGIGMTKAELINNLGTIAKSGTKAFMEALSAGADVS--MIGQFGVG 124
+ E+ + I+D+GIGMT+ EL++NLGTIA+SG+KAF++AL A+ S +IGQFGVG
Sbjct: 145 LQTNAEKGTITIQDTGIGMTQEELVSNLGTIARSGSKAFLDALQNQAEASSKIIGQFGVG 204
Query: 125 FYSLFLVADRVQVISKHNDDEQ--YIWESNAGGSFTVTLDESNERIGRGTVLRLFLKEDQ 182
FYS F+VADRV+V S+ Y W S+ G F + + GT + + LK D
Sbjct: 205 FYSAFMVADRVEVYSRSAAPGSLGYQWLSDGSGVFEIA---EASGVRTGTKIIIHLKSDC 261
Query: 183 LEYLEEKRIKDVVKKHSEFVAYPIQL 208
E+ E R++DVV K+S FV++P+ L
Sbjct: 262 KEFSSEARVRDVVTKYSNFVSFPLYL 287
Score = 174 bits (441), Expect = 4e-43
Identities = 112/410 (27%), Positives = 209/410 (50%), Gaps = 23/410 (5%)
Query: 280 LWTKNPSEVTQEEYNAFYKSISNDWEDPLAVKHFSVEGQLEFKAILFVP--KRAAFDLFE 337
+W +P +V + ++ FY+ ++ + P H+ + L ++I +VP K + FD+
Sbjct: 298 IWMMDPKDVGEWQHEEFYRYVAQAHDKPRYTLHYKTDAPLNIRSIFYVPDMKPSMFDV-- 355
Query: 338 SKKKKTNIKLYVRRVFITDEAEELIPEWLSFVKGVVDSEDLPLNLSREMLQQXXXXXXXX 397
S++ +++ LY R+V I +A +++P+WL F++GVVDSED+PLNLSRE+LQ+
Sbjct: 356 SRELGSSVALYSRKVLIQTKATDILPKWLRFIRGVVDSEDIPLNLSRELLQESALIRKLR 415
Query: 398 XXXXXXXXETF-NEIAEDSEQFDKFYTAFSKNIKLGIHEDTQN--RAALAKLLRYNSTK- 453
+ F ++ +D+E++ KF+ + ++ GI T+ + +AKLLRY S+
Sbjct: 416 DVLQQRLIKFFIDQSKKDAEKYAKFFEDYGLFMREGIVTATEQEVKEDIAKLLRYESSAL 475
Query: 454 SVDELTSLSDYVTRMPEHQKNIYFITGESIKAVEKSPFLDALKAKNFEVLFLVDPIDEYA 513
+LTSLS+Y +RM +NIY++ + E SP+ +A+K K+ EVLF + DE
Sbjct: 476 PSGQLTSLSEYASRMRAGTRNIYYLCAPNRHLAEHSPYYEAMKKKDTEVLFCFEQFDELT 535
Query: 514 FSQLKEFEGKQLVDITKDF------XXXXXXXXXXXXXXXXXXXXPLTTALKEILGDQVE 567
L+EF+ K+L+ + D L ++ +LG +V
Sbjct: 536 LLHLREFDKKKLISVETDIVVDHYKEEKFEDRSPAAECLSEKETEELMAWMRNVLGSRVT 595
Query: 568 KVVVSHKLLDAPAAIRTGQFGWSANMERIMKAQALRDSSMSSYMASKKIFEISPKSPIIR 627
V V+ +L PA + + G + ++ Q L + + EI+P+ +I+
Sbjct: 596 NVKVTLRLDTHPAMVTVLEMGAA---RHFLRMQQLAKTQEERAQLLQPTLEINPRHALIK 652
Query: 628 ELKN-KVEEGGAQDKTVKDLTNLLFETALLTSGFSLEEPSSFASRINRLI 676
+L + E G + L + ++E A++ +G +++P + R+N L+
Sbjct: 653 KLNQLRASEPG----LAQLLVDQIYENAMIAAGL-VDDPRAMVGRLNELL 697
>Hs22041160 [O] KOG0019 Molecular chaperone (HSP90 family)
Length = 343
Score = 165 bits (417), Expect = 3e-40
Identities = 90/140 (64%), Positives = 105/140 (74%), Gaps = 13/140 (9%)
Query: 5 ETYEFQAEITQLMSLIINTVYSNKEIFLRELISNASDALDKIRYQSLSDPKVLETEPELF 64
ET+ FQAEI QLMSLIINT YSNKEIFL ELISNASDALDKIRY+SL+DP L++ EL
Sbjct: 13 ETFAFQAEIAQLMSLIINTFYSNKEIFLWELISNASDALDKIRYESLTDPSKLDSGKELK 72
Query: 65 IRITPRPEEKVLEIRDSGIGMTKAELINNLGTIAKSGTKAFMEALSAGADVSMIGQFGVG 124
I I P +E L + D+GIGMTKA+LINNLGTIAK +SMIGQFG+G
Sbjct: 73 IDIIPNTQEHTLTLVDTGIGMTKADLINNLGTIAK-------------FHISMIGQFGIG 119
Query: 125 FYSLFLVADRVQVISKHNDD 144
FYS +LVA++V VI+K NDD
Sbjct: 120 FYSAYLVAEKVVVITKPNDD 139
Score = 102 bits (254), Expect = 2e-21
Identities = 65/176 (36%), Positives = 97/176 (54%), Gaps = 7/176 (3%)
Query: 428 NIKLGIHEDTQNRAA---LAKLLRYNSTKSVDELTSLSDYVTRMPEHQKNIYFITGESIK 484
NIKL +H + + + L + S DE+ SL +YV+RM E QK+IY+ITGES +
Sbjct: 171 NIKLYVHRVFIRDSCVELIPECLNFIRGVSGDEMISLLEYVSRMKEIQKSIYYITGESKE 230
Query: 485 AVEKSPFLDALKAKNFEVLFLVDPIDEYAFSQLKEFEGKQLVDITKD-FXXXXXXXXXXX 543
V S F++ + ++ V+++ +PID Y QLKEF+GK LV +TK+
Sbjct: 231 QVANSAFVEQVWKRDSRVVYMTEPIDGY---QLKEFDGKSLVSVTKEGLELPEDGEEKKR 287
Query: 544 XXXXXXXXXPLTTALKEILGDQVEKVVVSHKLLDAPAAIRTGQFGWSANMERIMKA 599
L +KE L +VE V VS++L+ + I T + W+ANME+IMKA
Sbjct: 288 MEERKAKFENLCKFMKETLDKKVEMVTVSNRLVSSSCCIVTSTYSWTANMEQIMKA 343
Score = 62.4 bits (150), Expect = 2e-09
Identities = 33/56 (58%), Positives = 38/56 (66%)
Query: 325 LFVPKRAAFDLFESKKKKTNIKLYVRRVFITDEAEELIPEWLSFVKGVVDSEDLPL 380
L V A F LFE+KKKK NIKLYV RVFI D ELIPE L+F++GV E + L
Sbjct: 152 LCVLTMAPFHLFENKKKKNNIKLYVHRVFIRDSCVELIPECLNFIRGVSGDEMISL 207
>CE29455 [O] KOG0019 Molecular chaperone (HSP90 family)
Length = 657
Score = 164 bits (415), Expect = 4e-40
Identities = 117/414 (28%), Positives = 202/414 (48%), Gaps = 25/414 (6%)
Query: 280 LWTKNPSEVTQEEYNAFYKSISND------WEDPLAVKHFSVEGQLEFKAILFVPKRAAF 333
+WT EV +E + F+K + + P HF + + ++++++P+
Sbjct: 239 IWTMQAREVNKEMHETFFKQLVKTQGKQEMYTRPQYTIHFQTDTPVSLRSVIYIPQTQFN 298
Query: 334 DL-FESKKKKTNIKLYVRRVFITDEAEELIPEWLSFVKGVVDSEDLPLNLSREMLQQXXX 392
L F +++ + LY RRV I +A+ELIP +L FV GVVDSED+PLNLSREMLQ
Sbjct: 299 QLTFMAQQTMCGLSLYARRVLIKPDAQELIPNYLRFVIGVVDSEDIPLNLSREMLQNNPV 358
Query: 393 XXXXXXXXXXXXXETF-NEIAEDSEQFDKFYTAFSKNIKLGI--HEDTQNRAALAKLLRY 449
+ +E+ +D ++ +F+ +S K G+ +D + +AKLL +
Sbjct: 359 LRKLRKIITDKILGSLQSEMKKDPVKYSEFFKNYSLYFKEGVVTEQDQGVKEDVAKLLLF 418
Query: 450 -NSTKSVDELTSLSDYVTRMPEHQKNIYFITGESIKAVEKSPFLDALKAKNFEVLFLVDP 508
+S+K ELTSL DYV RM E QK IY++ + + E SP+ + +K++N EVLFL DP
Sbjct: 419 ESSSKKAGELTSLGDYVKRMQEGQKEIYYMYANNRQLAESSPYYEVIKSQNKEVLFLYDP 478
Query: 509 IDEYAFSQLKEFEGKQLVDITK----DFXXXXXXXXXXXXXXXXXXXXPLTTALKEILGD 564
DE F L +F KQLV + K + L +KE LG
Sbjct: 479 ADEVVFLGLGQFGMKQLVPVEKWAQEEAEKTGTDDKKDTKDFRDNEKKELLDWMKETLGS 538
Query: 565 -QVEKVVVSHKLLDAPAAIRTGQFGWSANMERIMKAQALRDSSMSSYMASKKIFEISPKS 623
+V ++ +H+ + P + G + ++ ++D M + K ++
Sbjct: 539 VRVSEISGNHRPSEHPVMVTVLDMGAA---RHFLRTGEIKD--MEHLVYFKPHVHVNLTH 593
Query: 624 PIIRELKNKVEEGGAQDKTVKDLTNLLFETALLTSGFSLEEPSSFASRINRLIS 677
P+++ + + +T L +++ AL+T+G +++ S R+N+L++
Sbjct: 594 PLVKAMYKMRK---TDKETAAILAEQIYDNALITAGL-IKDTSRMVGRLNKLLT 643
Score = 146 bits (368), Expect = 1e-34
Identities = 89/206 (43%), Positives = 126/206 (60%), Gaps = 11/206 (5%)
Query: 5 ETYEFQAEITQLMSLIINTVYSNKEIFLRELISNASDALDKIRYQSLSDPKVLETEPELF 64
+ +EFQAE LM ++ ++YS+ E+F+RELISNASDAL+K RY L V E E
Sbjct: 28 QRHEFQAETRNLMDIVAKSLYSHSEVFVRELISNASDALEKRRYAELKG-DVAEGPSE-- 84
Query: 65 IRITPRPEEKVLEIRDSGIGMTKAELINNLGTIAKSGTKAFMEALSAGADVSMIGQFGVG 124
IRIT +++ + D+GIGM + +L+ LGTIAKSG+K F+E A+ ++IGQFGVG
Sbjct: 85 IRITTNKDKRTITFEDTGIGMNREDLVKFLGTIAKSGSKDFIENNKENAE-AVIGQFGVG 143
Query: 125 FYSLFLVADRVQVISK---HNDDEQYIWESNAGGSFTVTLDESNERIGRGTVLRLFLK-E 180
FYS F+VAD V V ++ +D + W N S+ + + GT + + LK
Sbjct: 144 FYSAFMVADSVVVTTRKVGSSDADGLQWTWNGDNSYEIA---ETSGLQTGTKIEIRLKVG 200
Query: 181 DQLEYLEEKRIKDVVKKHSEFVAYPI 206
D Y EE RIK+V+ K+S FV+ PI
Sbjct: 201 DSATYAEEDRIKEVINKYSYFVSAPI 226
>Hs22041746 [O] KOG0019 Molecular chaperone (HSP90 family)
Length = 1595
Score = 144 bits (364), Expect = 4e-34
Identities = 75/147 (51%), Positives = 104/147 (70%), Gaps = 2/147 (1%)
Query: 14 TQLMSLIINTVYSN--KEIFLRELISNASDALDKIRYQSLSDPKVLETEPELFIRITPRP 71
++L +L++ + ++ + L E + NA+ L + +SL+DP L++ E I + P
Sbjct: 615 SELCALVVGILLTSCHRHSRLAETMPNANLILPCLLPESLTDPSKLDSGKEPHISLIPNK 674
Query: 72 EEKVLEIRDSGIGMTKAELINNLGTIAKSGTKAFMEALSAGADVSMIGQFGVGFYSLFLV 131
+++ L I D+GIGMTKA+LINNLGTI KS TK FME L AGAD+SMIGQF VGFYS + V
Sbjct: 675 QDRTLTIVDTGIGMTKADLINNLGTITKSETKVFMEVLQAGADISMIGQFSVGFYSAYSV 734
Query: 132 ADRVQVISKHNDDEQYIWESNAGGSFT 158
A++V VI+KHN+DEQY WES+ GSFT
Sbjct: 735 AEKVTVITKHNNDEQYAWESSLRGSFT 761
Score = 132 bits (331), Expect = 2e-30
Identities = 64/98 (65%), Positives = 77/98 (78%)
Query: 292 EYNAFYKSISNDWEDPLAVKHFSVEGQLEFKAILFVPKRAAFDLFESKKKKTNIKLYVRR 351
EY FYKS++ +WED LAVKHFSVEGQLEF+A LFVP+ A F+L E++KKK IKL RR
Sbjct: 762 EYREFYKSLTINWEDYLAVKHFSVEGQLEFRAFLFVPRLAPFELLETRKKKNKIKLSARR 821
Query: 352 VFITDEAEELIPEWLSFVKGVVDSEDLPLNLSREMLQQ 389
I D EELIPE+L+F++GVVDSEDLPLN+ RE Q
Sbjct: 822 DLIMDNCEELIPEYLNFIRGVVDSEDLPLNIFRETKDQ 859
Score = 102 bits (253), Expect = 3e-21
Identities = 55/97 (56%), Positives = 68/97 (69%), Gaps = 1/97 (1%)
Query: 587 FGWSANMERIMKAQALRDSSMSSYMASKKIFEISPKSPIIRELKNKVEEGGAQDKTVKDL 646
+GW+ANMERIMKAQALRD+S + YMA+KK EI+P I L+ K E DK+VKDL
Sbjct: 902 YGWTANMERIMKAQALRDNSTTGYMAAKKHLEINPDHSFIDTLRQKAET-DKNDKSVKDL 960
Query: 647 TNLLFETALLTSGFSLEEPSSFASRINRLISLGLNID 683
LL+ETALL+S F LE P + A+RI R+ LGL D
Sbjct: 961 VILLYETALLSSDFGLEGPQTHANRIYRMNKLGLGTD 997
>Hs17451483 [O] KOG0019 Molecular chaperone (HSP90 family)
Length = 112
Score = 143 bits (361), Expect = 8e-34
Identities = 71/111 (63%), Positives = 84/111 (74%)
Query: 53 DPKVLETEPELFIRITPRPEEKVLEIRDSGIGMTKAELINNLGTIAKSGTKAFMEALSAG 112
D L++ L I + P + + L I D+ IGMTK +LINNLGT+ KSGTKAFMEAL A
Sbjct: 2 DSSKLDSGKGLHINLVPNKQNQTLTIVDTRIGMTKTDLINNLGTVTKSGTKAFMEALQAD 61
Query: 113 ADVSMIGQFGVGFYSLFLVADRVQVISKHNDDEQYIWESNAGGSFTVTLDE 163
AD+SMIG FGVGFYS +LVA +V VISKHN+DEQY WES+AGGSFTV DE
Sbjct: 62 ADISMIGHFGVGFYSAYLVAKKVTVISKHNNDEQYTWESSAGGSFTVRTDE 112
>Hs20545837_2 [O] KOG0019 Molecular chaperone (HSP90 family)
Length = 187
Score = 115 bits (287), Expect = 3e-25
Identities = 55/95 (57%), Positives = 70/95 (72%), Gaps = 1/95 (1%)
Query: 280 LWTKNPSEVTQEEYNAFYKSISNDWEDPLAVKHFSVEGQLEFKAILFVPKRAAFDLFESK 339
+WT+N +TQE Y F S +NDWED LAVKHFS+EGQLEF+A+LF+P RA FDLFE+
Sbjct: 39 IWTRNHDYITQE-YGEFCNSHTNDWEDHLAVKHFSIEGQLEFRALLFIPYRAPFDLFENN 97
Query: 340 KKKTNIKLYVRRVFITDEAEELIPEWLSFVKGVVD 374
K K IKLYV VFI +ELIPE L+F+ +++
Sbjct: 98 KNKDTIKLYVLHVFIVHSCDELIPEDLNFICAIME 132
>Hs22059125 [O] KOG0019 Molecular chaperone (HSP90 family)
Length = 192
Score = 100 bits (248), Expect = 1e-20
Identities = 51/107 (47%), Positives = 72/107 (66%)
Query: 383 SREMLQQXXXXXXXXXXXXXXXXETFNEIAEDSEQFDKFYTAFSKNIKLGIHEDTQNRAA 442
S+ MLQQ E F+E+AE E + KFY AFSKN+ LGIHED+ N+
Sbjct: 25 SQAMLQQSEILKVIHENVVKKWLEPFSELAEVKENYKKFYEAFSKNLNLGIHEDSTNQGR 84
Query: 443 LAKLLRYNSTKSVDELTSLSDYVTRMPEHQKNIYFITGESIKAVEKS 489
L++LL Y++++S DE+TSLS+Y++ M E QK+IY+ITGES + V+ S
Sbjct: 85 LSELLCYHTSQSEDEMTSLSEYLSHMKEAQKSIYYITGESKEQVDTS 131
>Hs17448897 [O] KOG0019 Molecular chaperone (HSP90 family)
Length = 101
Score = 97.8 bits (242), Expect = 5e-20
Identities = 49/102 (48%), Positives = 69/102 (67%), Gaps = 1/102 (0%)
Query: 569 VVVSHKLLDAPAAIRTGQFGWSANMERIMKAQALRDSSMSSYMASKKIFEISPKSPIIRE 628
+ + ++L+ +P I T +GW+ANME+IMKAQALRD+S YM +KK EI+P PI+
Sbjct: 1 MTIFNRLVSSPCCIVTSTYGWTANMEQIMKAQALRDNSTMGYMMAKKHLEINPNHPIVEM 60
Query: 629 LKNKVEEGGAQDKTVKDLTNLLFETALLTSGFSLEEPSSFAS 670
L+ K E K V+DL LLFET LL+SGF LE+P + ++
Sbjct: 61 LQQKA-EADRNSKAVRDLMVLLFETVLLSSGFFLEDPQTHSN 101
>Hs18549738 [O] KOG0019 Molecular chaperone (HSP90 family)
Length = 118
Score = 91.7 bits (226), Expect = 4e-18
Identities = 50/91 (54%), Positives = 65/91 (70%), Gaps = 2/91 (2%)
Query: 593 MERIMKAQALRDSSMSSYMASKKIFEISPKSPIIRELKNKVEEGGAQDKTVKDLTNLLFE 652
MERIMKAQ LRD+S YMA+KK EI+P II L+ K E + K+V+DL LL++
Sbjct: 1 MERIMKAQVLRDNSTMGYMAAKKHLEINPDHSIIETLRQKAEAD--KYKSVQDLVVLLYK 58
Query: 653 TALLTSGFSLEEPSSFASRINRLISLGLNID 683
TALL+SGF LE+P + A+RI R+I LG+ ID
Sbjct: 59 TALLSSGFGLEDPQTHANRIYRMIKLGVGID 89
>Hs20471111 [O] KOG0019 Molecular chaperone (HSP90 family)
Length = 217
Score = 72.4 bits (176), Expect = 2e-12
Identities = 35/43 (81%), Positives = 38/43 (87%)
Query: 88 AELINNLGTIAKSGTKAFMEALSAGADVSMIGQFGVGFYSLFL 130
A+LINNLGTIAKSGTKAFMEAL AGA +SMIGQFG GFY +L
Sbjct: 42 ADLINNLGTIAKSGTKAFMEALQAGARISMIGQFGFGFYCAYL 84
Score = 54.7 bits (130), Expect = 5e-07
Identities = 26/55 (47%), Positives = 37/55 (67%)
Query: 331 AAFDLFESKKKKTNIKLYVRRVFITDEAEELIPEWLSFVKGVVDSEDLPLNLSRE 385
A FDLF+ KKKK N+K+ + F D EELIP++L+ + +VD E LP +S+E
Sbjct: 107 APFDLFDKKKKKNNVKVCIDCEFTMDSCEELIPQYLNLMCSIVDFEALPWIISQE 161
>Hs18550811 [O] KOG0019 Molecular chaperone (HSP90 family)
Length = 329
Score = 68.2 bits (165), Expect = 4e-11
Identities = 34/76 (44%), Positives = 47/76 (61%)
Query: 349 VRRVFITDEAEELIPEWLSFVKGVVDSEDLPLNLSREMLQQXXXXXXXXXXXXXXXXETF 408
V RVFI D +EL E+L+F+ G+VDS+ LPLN+SREML+Q E F
Sbjct: 118 VHRVFIMDSCDELTQEFLNFIHGLVDSQYLPLNISREMLKQSKILKVIQTNIVKKCLELF 177
Query: 409 NEIAEDSEQFDKFYTA 424
+E+AED + + KF+ A
Sbjct: 178 SELAEDKKNYKKFHEA 193
Database: KOG eukaryal database 04/03
Posted date: Apr 14, 2003 1:07 PM
Number of letters in database: 30,389,216
Number of sequences in database: 60,738
Lambda K H
0.316 0.134 0.365
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 31,791,043
Number of Sequences: 60738
Number of extensions: 1206596
Number of successful extensions: 3683
Number of sequences better than 1.0e-05: 34
Number of HSP's better than 0.0 without gapping: 34
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 3498
Number of HSP's gapped (non-prelim): 69
length of query: 713
length of database: 30,389,216
effective HSP length: 114
effective length of query: 599
effective length of database: 23,465,084
effective search space: 14055585316
effective search space used: 14055585316
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.6 bits)