ORF STATUS Function Best COG Functional category Pathways and functional systems
r_klactIV3302 good EO KOG1046 Amino acid transport and metabolism Puromycin-sensitive aminopeptidase and related aminopeptidases
r_klactIV3302 good EO KOG1046 Posttranslational modification, protein turnover, chaperones Puromycin-sensitive aminopeptidase and related aminopeptidases
Only best alignment is shown:
BLASTP 2.2.3 [May-13-2002]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= r_klactIV3302 1119862 1117232 -877
(877 letters)
Database: KOG eukaryal database 04/03
60,738 sequences; 30,389,216 total letters
Searching..................................................done
Color Key for Alignment Scores: 
Score E
Sequences producing significant alignments: (bits) Value
YKL157w [EO] KOG1046 Puromycin-sensitive aminopeptidase and rela... 442 e-124
YHR047c [EO] KOG1046 Puromycin-sensitive aminopeptidase and rela... 429 e-120
SPBC1921.05 [EO] KOG1046 Puromycin-sensitive aminopeptidase and ... 429 e-119
Hs15451907 [EO] KOG1046 Puromycin-sensitive aminopeptidase and r... 411 e-114
7292091 [EO] KOG1046 Puromycin-sensitive aminopeptidase and rela... 385 e-106
CE10790 [EO] KOG1046 Puromycin-sensitive aminopeptidase and rela... 369 e-101
Hs22064092 [EO] KOG1046 Puromycin-sensitive aminopeptidase and r... 328 2e-89
ECU01g1470 [EO] KOG1046 Puromycin-sensitive aminopeptidase and r... 326 8e-89
ECU01g0140 [EO] KOG1046 Puromycin-sensitive aminopeptidase and r... 326 8e-89
ECU08g0070 [EO] KOG1046 Puromycin-sensitive aminopeptidase and r... 322 2e-87
Hs20534524 [EO] KOG1046 Puromycin-sensitive aminopeptidase and r... 313 1e-84
Hs4502095 [EO] KOG1046 Puromycin-sensitive aminopeptidase and re... 312 1e-84
Hs4503575 [EO] KOG1046 Puromycin-sensitive aminopeptidase and re... 311 2e-84
Hs11641261 [EO] KOG1046 Puromycin-sensitive aminopeptidase and r... 306 1e-82
7301751 [EO] KOG1046 Puromycin-sensitive aminopeptidase and rela... 303 1e-81
7299747 [EO] KOG1046 Puromycin-sensitive aminopeptidase and rela... 302 1e-81
Hs5031881 [EO] KOG1046 Puromycin-sensitive aminopeptidase and re... 298 3e-80
Hs7019561 [EO] KOG1046 Puromycin-sensitive aminopeptidase and re... 297 4e-80
7301772 [EO] KOG1046 Puromycin-sensitive aminopeptidase and rela... 286 7e-77
Hs20149637 [EO] KOG1046 Puromycin-sensitive aminopeptidase and r... 284 4e-76
7299744 [EO] KOG1046 Puromycin-sensitive aminopeptidase and rela... 283 6e-76
7301771 [EO] KOG1046 Puromycin-sensitive aminopeptidase and rela... 278 3e-74
7299745 [EO] KOG1046 Puromycin-sensitive aminopeptidase and rela... 278 3e-74
7300768 [EO] KOG1046 Puromycin-sensitive aminopeptidase and rela... 266 1e-70
At4g33090 [EO] KOG1046 Puromycin-sensitive aminopeptidase and re... 258 4e-68
CE21162 [EO] KOG1046 Puromycin-sensitive aminopeptidase and rela... 256 8e-68
7301770 [EO] KOG1046 Puromycin-sensitive aminopeptidase and rela... 249 1e-65
CE24087 [EO] KOG1046 Puromycin-sensitive aminopeptidase and rela... 248 3e-65
7301517 [EO] KOG1046 Puromycin-sensitive aminopeptidase and rela... 243 7e-64
7300767 [EO] KOG1046 Puromycin-sensitive aminopeptidase and rela... 232 2e-60
7300769 [EO] KOG1046 Puromycin-sensitive aminopeptidase and rela... 214 6e-55
CE18905 [EO] KOG1046 Puromycin-sensitive aminopeptidase and rela... 207 4e-53
CE20255 [EO] KOG1046 Puromycin-sensitive aminopeptidase and rela... 204 6e-52
CE18904 [EO] KOG1046 Puromycin-sensitive aminopeptidase and rela... 195 2e-49
CE27507 [EO] KOG1046 Puromycin-sensitive aminopeptidase and rela... 194 7e-49
7291179 [EO] KOG1046 Puromycin-sensitive aminopeptidase and rela... 191 4e-48
YIL137c [EO] KOG1046 Puromycin-sensitive aminopeptidase and rela... 179 2e-44
CE26001 [EO] KOG1046 Puromycin-sensitive aminopeptidase and rela... 177 5e-44
7291558 [EO] KOG1046 Puromycin-sensitive aminopeptidase and rela... 162 2e-39
7298258 [EO] KOG1046 Puromycin-sensitive aminopeptidase and rela... 157 9e-38
7291178 [EO] KOG1046 Puromycin-sensitive aminopeptidase and rela... 133 1e-30
CE13593 [EO] KOG1046 Puromycin-sensitive aminopeptidase and rela... 110 9e-24
CE05135 [EO] KOG1046 Puromycin-sensitive aminopeptidase and rela... 108 3e-23
Hs4505029 [IOVE] KOG1047 Bifunctional leukotriene A4 hydrolase/a... 97 8e-20
YNL045w [IOVE] KOG1047 Bifunctional leukotriene A4 hydrolase/ami... 94 7e-19
7300975 [EO] KOG1046 Puromycin-sensitive aminopeptidase and rela... 92 5e-18
7298498 [IOVE] KOG1047 Bifunctional leukotriene A4 hydrolase/ami... 91 6e-18
7294697 [EO] KOG1046 Puromycin-sensitive aminopeptidase and rela... 91 8e-18
CE24840 [IOVE] KOG1047 Bifunctional leukotriene A4 hydrolase/ami... 90 1e-17
At1g63770 [EO] KOG1046 Puromycin-sensitive aminopeptidase and re... 83 2e-15
Hs20537652 [IOVE] KOG1047 Bifunctional leukotriene A4 hydrolase/... 75 4e-13
Hs13443031 [IOVE] KOG1047 Bifunctional leukotriene A4 hydrolase/... 74 1e-12
At5g13520 [IOVE] KOG1047 Bifunctional leukotriene A4 hydrolase/a... 69 3e-11
CE28160 [IOVE] KOG1047 Bifunctional leukotriene A4 hydrolase/ami... 67 1e-10
SPCC1322.05c [IOVE] KOG1047 Bifunctional leukotriene A4 hydrolas... 65 6e-10
CE19614 [K] KOG1932 TATA binding protein associated factor 62 3e-09
CE00646 [EO] KOG1046 Puromycin-sensitive aminopeptidase and rela... 58 7e-08
Hs17472410 [EO] KOG1046 Puromycin-sensitive aminopeptidase and r... 56 3e-07
Hs20070296 [IOVE] KOG1047 Bifunctional leukotriene A4 hydrolase/... 55 4e-07
CE25399 [EO] KOG1046 Puromycin-sensitive aminopeptidase and rela... 54 8e-07
>YKL157w [EO] KOG1046 Puromycin-sensitive aminopeptidase and related
aminopeptidases
Length = 935
Score = 442 bits (1138), Expect = e-124
Identities = 302/884 (34%), Positives = 465/884 (52%), Gaps = 76/884 (8%)
Query: 7 QTLPTDFRANHYEIELSELDAEHNSFIGSVRIIMSTVN-ANDMISLNMRDIEIVSAVVEL 65
+ LP + HY++ + E D + F GSV+I + N A D ++LN D +I SA
Sbjct: 100 EILPDNVVPLHYDLTV-EPDFKTFKFEGSVKIELKINNPAIDTVTLNTVDTDIHSA---- 154
Query: 66 KEGSVSLGMKDHSFDLENDVVSLKFPE----SISDDEFVLKIDYKGMIQTNMSGFYRSDY 121
K G V+ + + E V + FP+ S + F L I + G++ NM+GFYR+ Y
Sbjct: 155 KIGDVT--SSEIISEEEQQVTTFAFPKGTMSSFKGNAF-LDIKFTGILNDNMAGFYRAKY 211
Query: 122 TDFVTGENKVMFSTQFEATDARRAFPCFDEPSLKATFDICIIAHEKYTVLANMPLKCTKK 181
D +TGE K M +TQ E TDARRAFPCFDEP+LKA+F I +++ T L+NM +K +
Sbjct: 212 EDKLTGETKYMATTQMEPTDARRAFPCFDEPNLKASFAITLVSDPSLTHLSNMDVK-NEY 270
Query: 182 LTESDQISYRFHTTPLMSTYLVAWAVGEYDYIESETEKSIYPTIENYNTQDGTSSGCGKL 241
+ + +++ F+TTP MSTYLVA+ V E Y+ES+ N+ ++
Sbjct: 271 VKDGKKVTL-FNTTPKMSTYLVAFIVAELKYVESK----------NF-----------RI 308
Query: 242 PVKVYTAKGKAQQGKFALDVAKRVIDFFSESFEIPYPLPKLDLLCVETYSHNAMENFSLI 301
PV+VY G + G+FA D+ + + FF ++F I YPLPK+D + V +S AMEN+ L+
Sbjct: 309 PVRVYATPGNEKHGQFAADLTAKTLAFFEKTFGIQYPLPKMDNVAVHEFSAGAMENWGLV 368
Query: 302 TFRPSALLYDGNLDEPDAAALQKIAYVVSHEIAHQWFGNLVTMKWWDELWLNEGFATWIG 361
T+R LL D D +Q++A VV HE+AHQWFGNLVTM WW+ LWLNEGFATW+
Sbjct: 369 TYRVVDLLLDK--DNSTLDRIQRVAEVVQHELAHQWFGNLVTMDWWEGLWLNEGFATWMS 426
Query: 362 YLAVEKFFPDWDVPSMIMLQSHEVALELDSLKESHPIKVAVRNAKDIDQVFDSISYLKGC 421
+ + +F P+W V + + + AL LDSL+ SHPI+V V+ A +I+Q+FD+ISY KG
Sbjct: 427 WYSCNEFQPEWKVWEQYVTDTLQHALSLDSLRSSHPIEVPVKKADEINQIFDAISYSKGA 486
Query: 422 SILEMVSGYLGQELFLKGVALYLKRNKFSNATMEDLFNCIGEVADIEVLERCKNWILTIG 481
S+L M+S +LG+E F+KGV+ YL + K+ NA EDL++ + + + +V W +G
Sbjct: 487 SLLRMISKWLGEETFIKGVSQYLNKFKYGNAKTEDLWDALADASGKDVRSVMNIWTKKVG 546
Query: 482 YPLVTVTESEIG-LSLTQNRFLSTGTCKPDEDVTKWWVPLMPLQGDYKVDFS------GK 534
+P+++V+E G ++ QNR+LST KPDED T + V + L+ VD S K
Sbjct: 547 FPVISVSEDGNGKITFRQNRYLSTADVKPDEDKTIYPV-FLALKTKNGVDSSVVLSERSK 605
Query: 535 TTELPKTQFNHFNANSFGFYRVKYDSDHLFQQQLQNLDKLSSRGKMGLISDVEVTEC--- 591
T EL F N+ G Y Y +D + + Q D LS ++GL++DV+
Sbjct: 606 TIELEDPTFFKVNSEQSGIYITSY-TDERWAKLGQQADLLSVEDRVGLVADVKTLSASGY 664
Query: 592 --VKNLLTLISKFTNHQDPNDYYVWSIIFDTLNRMKSL-LSSDKAVKKALDNFTLDLIQP 648
N L L+SK+ N + + VW I ++++ MKS L K + ALDNFT LI
Sbjct: 665 TSTTNFLNLVSKWNNEK---SFVVWDQIINSISSMKSTWLFEPKETQDALDNFTKQLISG 721
Query: 649 SIEKL-LEFLDQQKTNSFSKNPDNFLSNQFFELMALGAGTASHPETVAKCR-EMFE---- 702
L EF K+ D+F S Q ++ GA A+ V K +MF
Sbjct: 722 MTHHLGWEF----------KSSDSF-STQRLKVTMFGAACAARDADVEKAALKMFTDYCS 770
Query: 703 -SKSYSPVFRNVLLQIILSQPDXXXXXXXXXXXXXXXSTLVYKESLLTALGKIKNAELFD 761
+K P ++ +++ + K + L +LG+ K +L +
Sbjct: 771 GNKEAIPALIKPIVFNTVARVGGAENYEKVYKIYLDPISNDEKLAALRSLGRFKEPKLLE 830
Query: 762 TVLNLLL--IIEPMDVQFLATSLGSNYAIRTKLWNFIKTNYVKLHERLAINTVVIDRFLR 819
L L + D+ + ++ LWN++K N+ +L +RL ++ +
Sbjct: 831 RTLGYLFDGTVLNQDIYIPMQGMRAHQEGVEALWNWVKKNWDELVKRLPPGLSMLGSVVT 890
Query: 820 FSMKDLMGEDVKTDYELFFADKNMEGFDRGVRQTLERIEKNTRY 863
+ + FFA K+ +GFD+ + Q+L+ I ++
Sbjct: 891 LGTSGFTSMQKIDEIKKFFATKSTKGFDQSLAQSLDTITSKAQW 934
>YHR047c [EO] KOG1046 Puromycin-sensitive aminopeptidase and related
aminopeptidases
Length = 856
Score = 429 bits (1103), Expect = e-120
Identities = 280/894 (31%), Positives = 471/894 (52%), Gaps = 71/894 (7%)
Query: 7 QTLPTDFRANHYEIELSELDAEHNSFIGSVRI-IMSTVNANDMISLNMRDIEIVSAVVEL 65
+ LP + HY+I L E + +F GS++I + ++ + + +N +I+ SA +E
Sbjct: 4 EVLPNNVTPLHYDITL-EPNFRAFTFEGSLKIDLQINDHSINSVQINYLEIDFHSARIE- 61
Query: 66 KEGSVSLGMKDHSFDLENDVVSLKFPESISDD---EFVLKIDYKGMIQTNMSGFYRSDYT 122
+ + + + +L FP ++ L+I + G++ M+GFYR+ YT
Sbjct: 62 -----GVNAIEVNKNENQQKATLVFPNGTFENLGPSAKLEIIFSGILNDQMAGFYRAKYT 116
Query: 123 DFVTGENKVMFSTQFEATDARRAFPCFDEPSLKATFDICIIAHEKYTVLANMPLKCTKKL 182
D VTGE K M +TQ EATDARRAFPCFDEP+LKATF + +++ T L+NM ++ + +
Sbjct: 117 DKVTGETKYMATTQMEATDARRAFPCFDEPNLKATFAVTLVSESFLTHLSNMDVR-NETI 175
Query: 183 TESDQISYRFHTTPLMSTYLVAWAVGEYDYIESETEKSIYPTIENYNTQDGTSSGCGKLP 242
E + + F+TTP MSTYLVA+ V + Y+ES N+ ++P
Sbjct: 176 KEGKKYT-TFNTTPKMSTYLVAFIVADLRYVESN----------NF-----------RIP 213
Query: 243 VKVYTAKGKAQQGKFALDVAKRVIDFFSESFEIPYPLPKLDLLCVETYSHNAMENFSLIT 302
V+VY+ G + G+FA ++A R + FF ++F I YPLPK+D++ V +S AMEN+ L+T
Sbjct: 214 VRVYSTPGDEKFGQFAANLAARTLRFFEDTFNIEYPLPKMDMVAVHEFSAGAMENWGLVT 273
Query: 303 FRPSALLYDGNLDEPDAAALQKIAYVVSHEIAHQWFGNLVTMKWWDELWLNEGFATWIGY 362
+R LL D ++ +Q++A V+ HE+AHQWFGNLVTM WW+ LWLNEGFATW+ +
Sbjct: 274 YRVIDLLLD--IENSSLDRIQRVAEVIQHELAHQWFGNLVTMDWWEGLWLNEGFATWMSW 331
Query: 363 LAVEKFFPDWDVPSMIMLQSHEVALELDSLKESHPIKVAVRNAKDIDQVFDSISYLKGCS 422
+ KF P+W V + + + AL LDSL+ SHPI+V V NA +I+Q+FD+ISY KG S
Sbjct: 332 YSCNKFQPEWKVWEQYVTDNLQRALNLDSLRSSHPIEVPVNNADEINQIFDAISYSKGSS 391
Query: 423 ILEMVSGYLGQELFLKGVALYLKRNKFSNATMEDLFNCIGEVADIEVLERCKNWILTIGY 482
+L M+S +LG+E F+KGV+ YL + K+ NA DL++ + + + +V W +G+
Sbjct: 392 LLRMISKWLGEETFIKGVSQYLNKFKYGNAKTGDLWDALADASGKDVCSVMNIWTKRVGF 451
Query: 483 PLVTVTESEIGLSLTQNRFLSTGTCKPDEDVTKWWVPLMPLQGDYKVDFS------GKTT 536
P+++V E + ++LTQ+R+LSTG K +ED T + + L+ L+ +D + T
Sbjct: 452 PVLSVKEHKNKITLTQHRYLSTGDVKEEEDTTIYPI-LLALKDSTGIDNTLVLNEKSATF 510
Query: 537 ELPKTQFNHFNANSFGFYRVKYDSDHLFQQQLQNLDKLSSRGKMGLISDVEVTEC----- 591
EL +F N + G + Y SD + + + + LS ++GL++D +
Sbjct: 511 ELKNEEFFKINGDQSGIFITSY-SDERWAKLSKQANLLSVEDRVGLVADAKALSASGYTS 569
Query: 592 VKNLLTLISKFTNHQDPNDYYVWSIIFDTLNRMKSL-LSSDKAVKKALDNFTLDLIQPSI 650
N L LIS + N + + VW I ++L+ +KS + + + ALD FTLDL+ +
Sbjct: 570 TTNFLNLISNWKNE---DSFVVWEQIINSLSALKSTWVFEPEDILNALDKFTLDLVLNKL 626
Query: 651 EKLLEFLDQQKTNSFSKNPDNFLSNQFFELMALGAGTASHPETVAKCREMFE------SK 704
+L + + D+F + + A T+ + + + EMFE +
Sbjct: 627 SELGWNIGED---------DSFAIQRLKVTLFSAACTSGNEKMQSIAVEMFEEYANGNKQ 677
Query: 705 SYSPVFRNVLLQIILSQPDXXXXXXXXXXXXXXXSTLVYKESLLTALGKIKNAELFDTVL 764
+ +F+ V+ + S+ K L ALG+ ++ EL + L
Sbjct: 678 AIPALFKAVVFNTVARLGGENNYEKIFNIYQNPVSS-EEKIIALRALGRFEDKELLERTL 736
Query: 765 NLLLIIEPMDVQFLATSLGSNYAIR--TKLWNFIKTNYVKLHERLAINTVVIDRFLRFSM 822
+ LL ++ F G + +LW +++ ++ ++ +RL + V+ L +
Sbjct: 737 SYLLDGTVLNQDFYIPMQGIRVHKKGIERLWAWMQEHWDEIAKRLQPGSPVLGGVLTLGL 796
Query: 823 KDLMGEDVKTDYELFFADKNMEGFDRGVRQTLERIEKNTRYFETNLSLVKEYFK 876
+ + F++ K +GFD+ + Q L+ I ++ + +V Y +
Sbjct: 797 TNFTSFEALEKISAFYSRKVTKGFDQTLAQALDTIRSKAQWVSRDREIVATYLR 850
>SPBC1921.05 [EO] KOG1046 Puromycin-sensitive aminopeptidase and related
aminopeptidases
Length = 882
Score = 429 bits (1102), Expect = e-119
Identities = 282/900 (31%), Positives = 466/900 (51%), Gaps = 74/900 (8%)
Query: 9 LPTDFRANHYEIELSELDAEHNSFIGSVRIIMSTVNANDMISLNMRDIEIVSAVVELKEG 68
LP + + HY++ L D E ++ G V + + + ++ I+L+ ++ I++A +E G
Sbjct: 20 LPKNVKPIHYDLSLYP-DLETFTYGGKVVVTLDVLEDSNSITLHGINLRILTAALEW--G 76
Query: 69 SVSLGMKDHSFDLENDVVSLKFPESI-SDDEFVLKIDYKGMIQTNMSGFYRSDYTDFVTG 127
S ++ + S+ E V L+FP ++ ++ VL + + I + M GFYRS Y D G
Sbjct: 77 SQTVWASEVSYGDERIV--LQFPSTVPANSVAVLTLPFTARISSGMEGFYRSSYVDS-DG 133
Query: 128 ENKVMFSTQFEATDARRAFPCFDEPSLKATFDICIIAHEKYTVLANMPLKCTKKLTESDQ 187
K + +TQ E T ARRAFPC+DEP+LKATF I I A E YT+L+NM ++ +
Sbjct: 134 NTKYLATTQMEPTSARRAFPCWDEPALKATFTIDITAKENYTILSNM--NAVEETVKDGL 191
Query: 188 ISYRFHTTPLMSTYLVAWAVGEYDYIESETEKSIYPTIENYNTQDGTSSGCGKLPVKVYT 247
+ RF T MSTYL+AW V E +Y+E T C +LPV+VYT
Sbjct: 192 KTARFAETCRMSTYLLAWIVAELEYVEYFTP----------------GKHCPRLPVRVYT 235
Query: 248 AKGKAQQGKFALDVAKRVIDFFSESFEIPYPLPKLDLLCVETYSHNAMENFSLITFRPSA 307
G ++QGKFA ++ + +DFFS F PYPLPK D++ + + AMEN+ L+T+R +A
Sbjct: 236 TPGFSEQGKFAAELGAKTLDFFSGVFGEPYPLPKCDMVAIPDFEAGAMENWGLVTYRLAA 295
Query: 308 LLYDGNLDEPDAAALQKIAYVVSHEIAHQWFGNLVTMKWWDELWLNEGFATWIGYLAVEK 367
+L ++ A ++++A VV HE+AHQWFGNLVTM++WD LWLNEGFATW+ + +
Sbjct: 296 ILVS---EDSAATVIERVAEVVQHELAHQWFGNLVTMQFWDGLWLNEGFATWMSWFSCNH 352
Query: 368 FFPDWDVPSMIMLQSHEVALELDSLKESHPIKVAVRNAKDIDQVFDSISYLKGCSILEMV 427
F+P+W V + + + AL LD+L+ SHPI+V + + +I+Q+FD+ISY KG ++ MV
Sbjct: 353 FYPEWKVWESYVTDNLQSALSLDALRSSHPIEVPIMHDYEINQIFDAISYSKGSCVIRMV 412
Query: 428 SGYLGQELFLKGVALYLKRNKFSNATMEDLFNCIGEVADIEVLERCKNWILTIGYPLVTV 487
S Y+G++ F+KG+ Y+ ++++ N EDL+ + + ++ NW GYP+++V
Sbjct: 413 SKYVGEDTFIKGIQKYISKHRYGNTVTEDLWAALSAESGQDISSTMHNWTKKTGYPVLSV 472
Query: 488 TESEIG-LSLTQNRFLSTGTCKPDEDVTKWWVPL-MPLQGDYK--------VDFSGKTTE 537
+E+ G L + Q+RFLSTG KP+ED +W PL + D K + K +
Sbjct: 473 SETNDGELLIEQHRFLSTGDVKPEEDTVIYWAPLKLKTMKDGKAVVDEKAVLSDRSKKIK 532
Query: 538 LPKTQFNHFNANS--FGFYRVKYDSDH---LFQQQLQNLDKLSSRGKMGLISDVEVTE-- 590
+ K + NS G YRV Y +DH L Q ++ D LS + GLI+DV
Sbjct: 533 VDKEALESYKLNSEQSGIYRVNYSADHLKKLSQIAVEKPDYLSVEDRAGLIADVASLSRA 592
Query: 591 ---CVKNLLTLISKFTNHQDPNDYYVWSIIFDTLNRMKSLLSSDKAVKKALDNFTLDLIQ 647
V + L LI + +D ++ V++ + LN +KS L + + D+I
Sbjct: 593 GYGKVSSTLDLIKTW---KDEPNFVVFAEMLARLNGIKSTLRFESS----------DII- 638
Query: 648 PSIEKLLEFLDQQKTNSFS---KNPDNFLSNQFFELMALGAGTASHPETVAKCREMFES- 703
+++KL+ + K +S K D+ + QF + AG + V F++
Sbjct: 639 AAMKKLVLEVSATKAHSLGWEFKANDDHIIRQFKSTVYNYAGLFGDDKVVKDALSKFDAY 698
Query: 704 -----KSYSPVFRNVLLQIILSQPDXXXXXXXXXXXXXXXSTLVYKESLLTALGKIKNAE 758
+ + R+ + I + V + S L A G ++ +
Sbjct: 699 ASGNKSAINDNLRSAVFNIAIRYGGAKSWDQLLEIYTKTNDPYV-RNSCLRAFGVTEDEK 757
Query: 759 LFDTVLNLLL--IIEPMDVQFLATSLGSNYAIRTKLWNFIKTNYVKLHERLAINTVVIDR 816
L+L L I++ D+ + +L ++ +W F +N+ KL RL + +
Sbjct: 758 YIQKTLDLTLDPIVKEQDIYLILVTLSTHKNGVLAMWKFATSNWDKLLSRLPVAGTMRGY 817
Query: 817 FLRFSMKDLMGEDVKTDYELFFADKNMEGFDRGVRQTLERIEKNTRYFETNLSLVKEYFK 876
+RF + FFADK+ + ++R ++Q+L+ I N+ + + +L + + K
Sbjct: 818 VVRFVTSGFTHASAIDKIKEFFADKDTKLYERALQQSLDTISANSSFIDKSLDDITRWLK 877
>Hs15451907 [EO] KOG1046 Puromycin-sensitive aminopeptidase and related
aminopeptidases
Length = 875
Score = 411 bits (1057), Expect = e-114
Identities = 282/906 (31%), Positives = 445/906 (48%), Gaps = 87/906 (9%)
Query: 7 QTLPTDFRANHYEIELSELDAEHNSFIGSVRIIMSTVNANDMISLNMRDIEIVSAVVELK 66
+ LP D +Y + L D +F G + A + I +N DI+I++A
Sbjct: 8 ERLPADVSPINYSLCLKP-DLLDFTFEGKLEAAAQVRQATNQIVMNCADIDIITASYA-P 65
Query: 67 EGSVSLGMKDHSFDLENDVVSLKFPESISDDEFVLKIDYKGMIQTNMSGFYRSDYTDFVT 126
EG + ++ E++ V+L FP ++ LKID+ G + M GFYRS YT +
Sbjct: 66 EGDEEIHATGFNYQNEDEKVTLSFPSTLQTGTGTLKIDFVGELNDKMKGFYRSKYTT-PS 124
Query: 127 GENKVMFSTQFEATDARRAFPCFDEPSLKATFDICIIAHEKYTVLANMPLKCTKKLTESD 186
GE + TQFEATDARRAFPC+DEP++KATFDI ++ + L+NM + K + +
Sbjct: 125 GEVRYAAVTQFEATDARRAFPCWDEPAIKATFDISLVVPKDRVALSNMNVIDRKPYPDDE 184
Query: 187 Q-ISYRFHTTPLMSTYLVAWAVGEYDYIESETEKSIYPTIENYNTQDGTSSGCGKLPVKV 245
+ +F TP+MSTYLVA+ VGEYD++E+ ++ + V+V
Sbjct: 185 NLVEVKFARTPVMSTYLVAFVVGEYDFVETRSKDGVC--------------------VRV 224
Query: 246 YTAKGKAQQGKFALDVAKRVIDFFSESFEIPYPLPKLDLLCVETYSHNAMENFSLITFRP 305
YT GKA+QGKFAL+VA + + F+ + F +PYPLPK+DL+ + ++ AMEN+ L+T+R
Sbjct: 225 YTPVGKAEQGKFALEVAAKTLPFYKDYFNVPYPLPKIDLIAIADFAAGAMENWGLVTYRE 284
Query: 306 SALLYDGNLDEPDAAALQKIAYVVSHEIAHQWFGNLVTMKWWDELWLNEGFATWIGYLAV 365
+ALL D +++ Q +A VV HE+AHQWFGNLVTM+WW LWLNEGFA+WI YL V
Sbjct: 285 TALLIDPK--NSCSSSRQWVALVVGHELAHQWFGNLVTMEWWTHLWLNEGFASWIEYLCV 342
Query: 366 EKFFPDWDVPSMIMLQSHEVALELDSLKESHPIKVAVRNAKDIDQVFDSISYLKGCSILE 425
+ FP++D+ + + + A ELD+L SHPI+V+V + ++D++FD+ISY KG S++
Sbjct: 343 DHCFPEYDIWTQFVSADYTRAQELDALDNSHPIEVSVGHPSEVDEIFDAISYSKGASVIR 402
Query: 426 MVSGYLGQELFLKGVALYLKRNKFSNATMEDLFNCIGEVADIEVLERCKNWILTIGYPLV 485
M+ Y+G + F KG+ +YL + + NA EDL+ + + + W +G+PL+
Sbjct: 403 MLHDYIGDKDFKKGMNMYLTKFQQKNAATEDLWESLENASGKPIAAVMNTWTKQMGFPLI 462
Query: 486 TVTESEIG----LSLTQNRFLSTGTCKPDEDVTKWWVPLM------PLQGDYKV-----D 530
V ++ L L+Q +F + G+ ED +W VP+ P Q K+ +
Sbjct: 463 YVEAEQVEDDRLLRLSQKKFCAGGS-YVGEDCPQWMVPITISTSEDPNQAKLKILMDKPE 521
Query: 531 FSGKTTELPKTQFNHFNANSFGFYRVKYDSDHL-------FQQQLQNLDKLS------SR 577
+ + Q+ N + GFYR +Y S L L +D+L S
Sbjct: 522 MNVVLKNVKPDQWVKLNLGTVGFYRTQYSSAMLESLLPGIRDLSLPPVDRLGLQNDLFSL 581
Query: 578 GKMGLISDVEVTECVKNLLTLISKFTNHQDPNDYYVWSIIFDTLNRMKSLLSSDKAVKKA 637
+ G+IS VEV L ++ F N +PN Y VWS + L + +LLS ++
Sbjct: 582 ARAGIISTVEV-------LKVMEAFVN--EPN-YTVWSDLSCNLGILSTLLSHTDFYEE- 630
Query: 638 LDNFTLDLIQPSIEKLLEFLDQQKTNSFSKNPDNFLSNQFFELMALG-AGTASHPETVAK 696
+ F D+ P E+L + P + + LG G A H T+ +
Sbjct: 631 IQEFVKDVFSPIGERL----------GWDPKPGEGHLDALLRGLVLGKLGKAGHKATLEE 680
Query: 697 CREMFE-----SKSYSPVFRNVLLQIILSQPDXXXXXXXXXXXXXXXSTLVYKESLLTAL 751
R F+ + S R+ + +L D K + L
Sbjct: 681 ARRRFKDHVEGKQILSADLRSPVYLTVLKHGD-GTTLDIMLKLHKQADMQEEKNRIERVL 739
Query: 752 GKIKNAELFDTVLNLLLI--IEPMD-VQFLATSLGSNYAIRTKLWNFIKTNYVKLHERLA 808
G +L VL L + P D V + G + R W FIK N+ +L+ R
Sbjct: 740 GATLLPDLIQKVLTFALSEEVRPQDTVSVIGGVAGGSKHGRKAAWKFIKDNWEELYNRYQ 799
Query: 809 INTVVIDRFLRFSMKDLMGEDVKTDYELFFADKNMEGFDRGVRQTLERIEKNTRYFETNL 868
+I R ++ S++ + + + + FF +R ++Q E I N + + +
Sbjct: 800 -GGFLISRLIKLSVEGFAVDKMAGEVKAFFESHPAPSAERTIQQCCENILLNAAWLKRDA 858
Query: 869 SLVKEY 874
+ +Y
Sbjct: 859 ESIHQY 864
>7292091 [EO] KOG1046 Puromycin-sensitive aminopeptidase and related
aminopeptidases
Length = 866
Score = 385 bits (990), Expect = e-106
Identities = 268/890 (30%), Positives = 439/890 (49%), Gaps = 72/890 (8%)
Query: 5 KIQTLPTDFRANHYEIELSELDAEHNSFIGSVRIIMSTVNANDMISLNMRDIEIVSAVVE 64
K + LPT+ HYE+ L + + + +F G + ++ I+LN DI + S VE
Sbjct: 6 KFERLPTNVVPRHYEL-LLQPNLKEFTFTGKTVVQVNVKEPTTQITLNALDIVLDS--VE 62
Query: 65 LKEGSVSLGMKDHSFDLENDVVSLKFPESI-SDDEFVLKIDYKGMIQTNMSGFYRSDYTD 123
L L + + EN+ +L+F + I ++ + VL + + G + M GFYRS Y
Sbjct: 63 LHFECSKLKPEKIVYSAENETATLEFAQEIPAETQGVLHMSFTGELNDKMKGFYRSKYFG 122
Query: 124 FVTGENKVMFSTQFEATDARRAFPCFDEPSLKATFDICIIAHEKYTVLANMPLKCTKKLT 183
GE + TQFEATDARR FPC+DEP++KATFDI ++ + L+NMP+ L
Sbjct: 123 -PNGEERFAGVTQFEATDARRCFPCWDEPAIKATFDITLVVPKDRVALSNMPVIKEDSLP 181
Query: 184 ESDQISYRFHTTPLMSTYLVAWAVGEYDYIESETEKSIYPTIENYNTQDGTSSGCGKLPV 243
+ + RF TP+MSTYLVA VGEYDY+E +++ + V
Sbjct: 182 DGLR-RVRFDRTPIMSTYLVAVVVGEYDYVEGKSDDGVL--------------------V 220
Query: 244 KVYTAKGKAQQGKFALDVAKRVIDFFSESFEIPYPLPKLDLLCVETYSHNAMENFSLITF 303
+V+T GK +QG FAL+VA +V+ ++ + F I YPLPK+DL+ + +S AMEN+ L+T+
Sbjct: 221 RVFTPVGKREQGTFALEVATKVLPYYKDYFNIAYPLPKMDLIAISDFSAGAMENWGLVTY 280
Query: 304 RPSALLYDGNLDEPDAAALQKIAYVVSHEIAHQWFGNLVTMKWWDELWLNEGFATWIGYL 363
R + +L D Q IA V HEIAHQWFGNLVTM+WW LWLNEG+A+++ +L
Sbjct: 281 RETFVLVDPK--NTSLMRKQSIALTVGHEIAHQWFGNLVTMEWWTHLWLNEGYASFVEFL 338
Query: 364 AVEKFFPDWDVPSMIMLQSHEVALELDSLKESHPIKVAVRNAKDIDQVFDSISYLKGCSI 423
V FP++D+ + + + ALELDSLK SHPI+V V + +ID++FD ISY KG S+
Sbjct: 339 CVHHLFPEYDIWTQFVTDMYTRALELDSLKNSHPIEVPVGHPSEIDEIFDEISYNKGASV 398
Query: 424 LEMVSGYLGQELFLKGVALYLKRNKFSNATMEDLFNCIGEVADIEVLERCKNWILTIGYP 483
+ M+ Y+G++ F KG+ LYL R+++ N EDL+ + E + V + +W G+P
Sbjct: 399 IRMLHDYIGEDTFRKGMNLYLTRHQYGNTCTEDLWAALQEASSKNVSDVMTSWTQHKGFP 458
Query: 484 LVTVTESEIG-----LSLTQNRFLSTGTCKPDEDVTKWWVPL--------MPLQGDYKVD 530
+V+V + L L Q +F + G+ + DE+ W VP+ + + +D
Sbjct: 459 VVSVESEQTSKNQRLLRLKQCKFTADGS-QADENCL-WVVPISVSTSKNPTGIAKTFLLD 516
Query: 531 FSGKTTELPKTQFNHF---NANSFGFYRVKYDSDHLFQQQLQNLDK--LSSRGKMGLISD 585
S L + + N + G+YR +Y S + +Q + ++K L ++GLI D
Sbjct: 517 KSSMEVTLDNVDEDDWIKINPGTVGYYRTRY-SQEMLEQLMPAVEKMELPPLDRLGLIDD 575
Query: 586 VEVT-----ECVKNLLTLISKFTNHQDPNDYYVWSIIFDTLNRMKSLLSSDKAVKKALDN 640
+ ++L L+ + N +Y VW+ I ++L + L+S ++
Sbjct: 576 MFAMVQAGHASTADVLALVDSYRNE---TNYTVWTAITNSLTNLHILISHTDLMED-FHR 631
Query: 641 FTLDLIQPSIEKLLEFLDQQKTNSFSKNPDNFLSNQFFELMALGAGTASHPETVAKCREM 700
F +L +P +L + + D L + + + + E + R
Sbjct: 632 FGRNLYEPVAYRL-----GWEPRDGENHLDTLLRSLVLTRLVSFRSSDTIEEAKIRFRRH 686
Query: 701 FESKSYSPV-FRNVLLQIILSQPDXXXXXXXXXXXXXXXSTLVYKES--LLTALGKIKNA 757
P R + +L D +T +++E + ALG +
Sbjct: 687 VNGTELLPADLRTTCYKAVLQDGD---EKIFNEMLDLYRATDLHEEQDRISRALGCCGDL 743
Query: 758 ELFDTVLNLLLI--IEPMDVQFLATSLGSNYAIRTKLWNFIKTNYVKLHERLAINTVVID 815
+L V++ + + D F+ ++ N R W F K N +L ER ++
Sbjct: 744 KLLRRVIDFAMSSEVRAQDSVFVIVAVAINPKGRDMAWEFFKENNKQLLERYQ-GGFLLS 802
Query: 816 RFLRFSMKDLMGEDVKTDYELFFADKNMEGFDRGVRQTLERIEKNTRYFE 865
R +++ +++ E+ + E F + G +R V Q +E I N + +
Sbjct: 803 RLIKYLIENFASEERAKEVEEFLQVNQIPGCERTVSQAVETIRLNAAWLQ 852
>CE10790 [EO] KOG1046 Puromycin-sensitive aminopeptidase and related
aminopeptidases
Length = 884
Score = 369 bits (946), Expect = e-101
Identities = 252/908 (27%), Positives = 443/908 (48%), Gaps = 69/908 (7%)
Query: 2 ADVKIQTLPTDFRANHYEIELSELDAEHNSFIGSVRIIMSTVNANDMISLNMRDIEIVSA 61
A VK + LPT HY + LS SF G I ++ A D++ ++ + + I S
Sbjct: 9 AAVKFERLPTFAEPTHYNVRLSPC-LNQFSFDGHATIDVTIKEATDVLKVHAQSLLIQSV 67
Query: 62 VVELKEGSVSLGMKDHSFDLENDVVSLKFPESISDDEFVLKIDYKGMIQTNMSGFYRSDY 121
+ + G S ++ S+D + +++++K P ++ + L + G + M GFYRS Y
Sbjct: 68 SLITQPGDASKSLET-SYDDKLNILTIKLPTTMQPQKVQLDFKFVGELNDKMRGFYRSQY 126
Query: 122 TDFVTGENKVMFSTQFEATDARRAFPCFDEPSLKATFDICIIAHEKYTVLANMPLKCTKK 181
D G K + STQFE+T AR AFPCFDEP KATFD+ + T L+NM +
Sbjct: 127 KD-KNGTEKFLASTQFESTYARYAFPCFDEPIYKATFDVTLEVENHLTALSNMNVISETP 185
Query: 182 LTESDQISYRFHTTPLMSTYLVAWAVGEYDYIESETEKSIYPTIENYNTQDGTSSGCGKL 241
+ + + F T+P MS+YLVA+AVGE +YI ++T+ +
Sbjct: 186 TADGKRKAVTFATSPKMSSYLVAFAVGELEYISAQTKSGV-------------------- 225
Query: 242 PVKVYTAKGKAQQGKFALDVAKRVIDFFSESFEIPYPLPKLDLLCVETYSHNAMENFSLI 301
++VYT GK +QG+++LD++ + ID+++E F+I YPLPK DL+ + +S AMEN+ L+
Sbjct: 226 EMRVYTVPGKKEQGQYSLDLSVKCIDWYNEWFDIKYPLPKCDLIAIPDFSMGAMENWGLV 285
Query: 302 TFRPSALLYDGNLDEPDAAALQKIAYVVSHEIAHQWFGNLVTMKWWDELWLNEGFATWIG 361
T+R ALL D + + ++A VV+HE+AH WFGNLVTMKWW +LWL EGFA+++
Sbjct: 286 TYREIALLVDPGVTSTRQKS--RVALVVAHELAHLWFGNLVTMKWWTDLWLKEGFASFME 343
Query: 362 YLAVEKFFPDWDVPSMIMLQSHEVALELDSLKESHPIKVAVRNAKDIDQVFDSISYLKGC 421
Y+ V P++ + + + LD+L+ SHPI+V + N ++D+++DSI+Y K
Sbjct: 344 YMFVGANCPEFKIWLHFLNDELASGMGLDALRNSHPIEVEIDNPNELDEIYDSITYAKSN 403
Query: 422 SILEMVSGYLGQELFLKGVALYLKRNKFSNATMEDLFNCIGEVADIEVLERCKNWILTIG 481
S+ M+ YL + +F KG+ LYLKR ++SNA +DL+ + E + V E W +G
Sbjct: 404 SVNRMLCYYLSEPVFQKGLRLYLKRFQYSNAVTQDLWTALSEASGQNVNELMSGWTQQMG 463
Query: 482 YPLVTVTESEIG----LSLTQNRFLSTGTCKPDEDVTKWWVPLMPLQG----DYKVDFSG 533
+P++ V++ + G L++ Q RF+S G P ++W VP+ G D K F
Sbjct: 464 FPVLKVSQRQDGNNRILTVEQRRFISDGGEDPKN--SQWQVPITVAVGSSPSDVKARFLL 521
Query: 534 KTTELPKT-------QFNHFNANSFGFYRVKYDSDHLFQQQLQNL--DKLSSRGKMGLIS 584
K + T ++ N+ + GFYRV+Y SD + L ++ ++ + GLI+
Sbjct: 522 KEKQQEFTIEGVAPGEWVKLNSGTTGFYRVEY-SDEMLTAMLPDIASRRMPVLDRFGLIN 580
Query: 585 DVE--VTECVKNLLTLISKFTNHQDPNDYYVWSIIFDTLNRMKSLLSSDKAVKKALDNFT 642
D+ + ++ + + ++Y VW I + ++++ A + + T
Sbjct: 581 DLSALLNTGRVSIAQFVQVAASSAKEDEYVVWGAIDEGMSKL-------LACAREMSEDT 633
Query: 643 LDLIQPSIEKLLEFLDQQKTNSFSKNPDNFLSNQFFELMALGAGTASHPETVAKCREMFE 702
L + + K+ E + + D+ L+ A H T+ K +MF
Sbjct: 634 LKSAKQLVVKMFEQTGAELGFAEQAGEDS-QKMMLRSLVQARLARAGHQPTIDKFTQMFN 692
Query: 703 S--KSYSPVFRNVLLQI--ILSQPDXXXXXXXXXXXXXXXSTLVYKESLLTALGKIKNAE 758
+ +P+ ++ L ++++ + + + A+ +
Sbjct: 693 DFLEKGTPIHPDIRLATFGVVARYGGKEGFDKLMNLRETTTFQEIERQTMVAMSQTPEES 752
Query: 759 LFDTVLNLLL---IIEPMDVQFLATSLGSNYAIRTKLWNFIKTNYVKLHERL-AINTVVI 814
L + + P D +L G+ + + W + + + ++ N+ +
Sbjct: 753 LLAQLFEYGFEKNKVRPQDQLYLFLGTGATHMGQQYAWKYFCEHIKEFLDKYGGANSSLF 812
Query: 815 DRFLRFSMKDLMGEDVKTDYELFF------ADKNMEGFDRGVRQTLERIEKNTRYFETNL 868
R L+F+ + E +++ FF +D + + R + QT+E I N R E+N
Sbjct: 813 QRCLKFAGESFGNEKRAVEFQDFFCNCNVLSDTDRQTLARPIGQTVEAIRLNARLLESNR 872
Query: 869 SLVKEYFK 876
+++ K
Sbjct: 873 QIIENLLK 880
>Hs22064092 [EO] KOG1046 Puromycin-sensitive aminopeptidase and related
aminopeptidases
Length = 478
Score = 328 bits (841), Expect = 2e-89
Identities = 173/428 (40%), Positives = 261/428 (60%), Gaps = 25/428 (5%)
Query: 31 SFIGSVRIIMSTVNANDMISLNMRDIEIVSAVVELKEGSVSLGMKDHSFDLENDVVSLKF 90
+F G + A + I +N DI+I++A EG + ++ E++ V+L F
Sbjct: 75 TFEGKLEAAAQVRQATNQIVMNCADIDIITASYA-PEGDEEIHATGFNYQNEDEKVTLSF 133
Query: 91 PESISDDEFVLKIDYKGMIQTNMSGFYRSDYTDFVTGENKVMFSTQFEATDARRAFPCFD 150
P ++ LKID+ G + M GFYRS YT +GE + TQFEATDARRAFPC+D
Sbjct: 134 PSTLQTGTGTLKIDFVGELNDKMKGFYRSKYTT-PSGEVRYAAVTQFEATDARRAFPCWD 192
Query: 151 EPSLKATFDICIIAHEKYTVLANMPLKCTKKLTESDQ-ISYRFHTTPLMSTYLVAWAVGE 209
E ++KATFDI ++ + L+NM + K + + + +F TP+ STYLVA+ VGE
Sbjct: 193 ERAIKATFDISLVVPKDRVALSNMNVIDRKPYPDDENLVEVKFARTPVTSTYLVAFVVGE 252
Query: 210 YDYIESETEKSIYPTIENYNTQDGTSSGCGKLPVKVYTAKGKAQQGKFALDVAKRVIDFF 269
YD++E+ ++ + V VYT GKA+QGKFAL+VA + + F+
Sbjct: 253 YDFVETRSKDGVC--------------------VCVYTPVGKAEQGKFALEVAAKTLPFY 292
Query: 270 SESFEIPYPLPKLDLLCVETYSHNAMENFSLITFRPSALLYDGNLDEPDAAALQKIAYVV 329
+ F +PYPLPK+DL+ + ++ AMEN+ L+T+R +ALL D +++ Q +A VV
Sbjct: 293 KDYFNVPYPLPKIDLIAIADFAAGAMENWDLVTYRETALLIDPK--NSCSSSRQWVALVV 350
Query: 330 SHEIAHQWFGNLVTMKWWDELWLNEGFATWIGYLAVEKFFPDWDVPSMIMLQSHEVALEL 389
HE+AHQWFGNLVTM+WW L LNEGFA+WI YL V+ FP++D+ + + + A EL
Sbjct: 351 GHELAHQWFGNLVTMEWWTHLRLNEGFASWIEYLCVDHCFPEYDIWTQFVSADYTRAQEL 410
Query: 390 DSLKESHPIKVAVRNAKDIDQVFDSISYLKGCSILEMVSGYLGQELFLKGVALYLKRNKF 449
D+L SHPI+V+V + ++D++FD+ISY KG S++ M+ Y+G + F KG+ +YL + +
Sbjct: 411 DALDNSHPIEVSVGHPSEVDEIFDAISYSKGASVIRMLHDYIGDKDFKKGMNMYLTKFQQ 470
Query: 450 SNATMEDL 457
NA +L
Sbjct: 471 KNAAAGNL 478
>ECU01g1470 [EO] KOG1046 Puromycin-sensitive aminopeptidase and related
aminopeptidases
Length = 864
Score = 326 bits (836), Expect = 8e-89
Identities = 217/669 (32%), Positives = 344/669 (50%), Gaps = 59/669 (8%)
Query: 17 HYEIELSELDAEHNSFIGSVRIIMSTVNANDMISLNMRDIEIVSAVVELKEGSVSLGMKD 76
HY++ + LDA F GSV I + I LN +++EI A + ++ + +
Sbjct: 38 HYDLHVKILDA---GFCGSVGIRVMISQDVSEIVLNAKELEIRDAGIVVEGARIPGRVVV 94
Query: 77 HSFDLENDVVSLKFPESISDDEFVLKIDYKGMIQTNMSGFYRSDYTDFVTGENKVMFSTQ 136
+ E +VV + FP S+ L +++ G + G Y+S G K ++ST
Sbjct: 95 GEAEKELEVVRIVFPSSLRAGPGYLTMEFCGDYSNGLVGLYKS-------GGPKEVYSTH 147
Query: 137 FEATDARRAFPCFDEPSLKATFDICIIAHEKYTVLANMPLKCTKKLTESDQISYRFHTTP 196
FE TDARRAFPCFD+P +KATF I I A K+TVLAN + + D+ F T
Sbjct: 148 FEPTDARRAFPCFDQPDMKATFKISIDAGSKFTVLANTQAIPSLREEYGDRKIEYFEETC 207
Query: 197 LMSTYLVAWAVGEYDYIESETEKSIYPTIENYNTQDGTSSGCGKLPVKVYTAKGKAQQGK 256
MSTYLVA+ VGE YIE ++ + ++VY + + G+
Sbjct: 208 KMSTYLVAFVVGELSYIEDWSKDGVR--------------------LRVYGDSSEVEWGR 247
Query: 257 FALDVAKRVIDFFSESFEIPYPLP-----KLDLLCVETYSHNAMENFSLITFRPSALLY- 310
+ L+V KR +++FSE F + Y P K+D++ + +S AMEN+ LITFR +LLY
Sbjct: 248 YGLEVGKRCLEYFSEYFGVGYEFPRAGSAKIDMVGIPNFSSGAMENWGLITFRRESLLYV 307
Query: 311 DGNLDEPDAAALQKIAYVVSHEIAHQWFGNLVTMKWWDELWLNEGFATWIGYLAVEKF-- 368
G + D ++ +A V HE+ H WFGNLVTM WWD+LWLNEGFATW+ + +E
Sbjct: 308 PGKSNVED---MKNVAGTVCHELGHMWFGNLVTMSWWDDLWLNEGFATWVSFKGMENIGS 364
Query: 369 FPDWDVPSMIMLQSHEVALELDSLKESHPIKVAVRNAKDIDQVFDSISYLKGCSILEMVS 428
WDV +L + + D L +SH I++ V + +I ++FDSISY KG S++ M+
Sbjct: 365 VVSWDVWGEFVLWNVVRGMVDDGLGKSHQIRMNVTDPGEIGEIFDSISYCKGASVIRMIE 424
Query: 429 GYLGQELFLKGVALYLKRNKFSNATMEDLFNCIGEVADIEVLERCKNWILTIGYPLVTVT 488
Y+G+ +F+ G+ Y+K + + N L+ IGE ++ E + WI GYP+V+V
Sbjct: 425 RYVGESVFMLGIRRYIKEHMYGNGNAMSLWKAIGEEYGEDISEMVEGWISQAGYPVVSVQ 484
Query: 489 ESEIGLSLTQNRFLSTGTCKPDEDVTKWWVPLMPL---QGDYKVDFSGK-TTELPKTQFN 544
+ L L+Q+R+ G K D+ + W +P++ +G +++ G+ TT ++
Sbjct: 485 DCGSSLVLSQSRYSMLG--KSDDSL--WTIPVVVSWEGKGQERIELRGRETTVRKRSSVY 540
Query: 545 HFNANSFGFYRVKYDSDHLFQQQLQNLDKLSSRGKMGLISDV-----EVTECVKNLLTLI 599
NA GFYRV YDS L + +D LS ++ +I DV + +++ L I
Sbjct: 541 KVNAEYGGFYRVLYDSAGLSGLE-SRIDSLSVVDRVNVIEDVFGLGFGLYGGLEHGLRRI 599
Query: 600 SKFTNHQDPNDYYVWSIIFDTLNRMKSLLSSDKAVKKALDNFTLDLIQPSIEKLLEFLDQ 659
S++ + + Y+V + L R++S+ D + +D +I P + ++ F
Sbjct: 600 SEYYS----DSYHVARSGIEKLLRLRSVFYDDAEIVSLIDKKVRKMILPCVGRIDVFDIG 655
Query: 660 QKTNSFSKN 668
S S N
Sbjct: 656 TSVESVSMN 664
>ECU01g0140 [EO] KOG1046 Puromycin-sensitive aminopeptidase and related
aminopeptidases
Length = 864
Score = 326 bits (836), Expect = 8e-89
Identities = 217/669 (32%), Positives = 344/669 (50%), Gaps = 59/669 (8%)
Query: 17 HYEIELSELDAEHNSFIGSVRIIMSTVNANDMISLNMRDIEIVSAVVELKEGSVSLGMKD 76
HY++ + LDA F GSV I + I LN +++EI A + ++ + +
Sbjct: 38 HYDLHVKILDA---GFCGSVGIRVMISQDVSEIVLNAKELEIRDAGIVVEGARIPGRVVV 94
Query: 77 HSFDLENDVVSLKFPESISDDEFVLKIDYKGMIQTNMSGFYRSDYTDFVTGENKVMFSTQ 136
+ E +VV + FP S+ L +++ G + G Y+S G K ++ST
Sbjct: 95 GEAEKELEVVRIVFPSSLRAGPGYLTMEFCGDYSNGLVGLYKS-------GGPKEVYSTH 147
Query: 137 FEATDARRAFPCFDEPSLKATFDICIIAHEKYTVLANMPLKCTKKLTESDQISYRFHTTP 196
FE TDARRAFPCFD+P +KATF I I A K+TVLAN + + D+ F T
Sbjct: 148 FEPTDARRAFPCFDQPDMKATFKISIDAGSKFTVLANTQAIPSLREEYGDRKIEYFEETC 207
Query: 197 LMSTYLVAWAVGEYDYIESETEKSIYPTIENYNTQDGTSSGCGKLPVKVYTAKGKAQQGK 256
MSTYLVA+ VGE YIE ++ + ++VY + + G+
Sbjct: 208 KMSTYLVAFVVGELSYIEDWSKDGVR--------------------LRVYGDSSEVEWGR 247
Query: 257 FALDVAKRVIDFFSESFEIPYPLP-----KLDLLCVETYSHNAMENFSLITFRPSALLY- 310
+ L+V KR +++FSE F + Y P K+D++ + +S AMEN+ LITFR +LLY
Sbjct: 248 YGLEVGKRCLEYFSEYFGVGYEFPRAGSAKIDMVGIPNFSSGAMENWGLITFRRESLLYV 307
Query: 311 DGNLDEPDAAALQKIAYVVSHEIAHQWFGNLVTMKWWDELWLNEGFATWIGYLAVEKF-- 368
G + D ++ +A V HE+ H WFGNLVTM WWD+LWLNEGFATW+ + +E
Sbjct: 308 PGKSNVED---MKNVAGTVCHELGHMWFGNLVTMSWWDDLWLNEGFATWVSFKGMENIGS 364
Query: 369 FPDWDVPSMIMLQSHEVALELDSLKESHPIKVAVRNAKDIDQVFDSISYLKGCSILEMVS 428
WDV +L + + D L +SH I++ V + +I ++FDSISY KG S++ M+
Sbjct: 365 VVSWDVWGEFVLWNVVRGMVDDGLGKSHQIRMNVTDPGEIGEIFDSISYCKGASVIRMIE 424
Query: 429 GYLGQELFLKGVALYLKRNKFSNATMEDLFNCIGEVADIEVLERCKNWILTIGYPLVTVT 488
Y+G+ +F+ G+ Y+K + + N L+ IGE ++ E + WI GYP+V+V
Sbjct: 425 RYVGESVFMLGIRRYIKEHMYGNGNAMSLWKAIGEEYGEDISEMVEGWISQAGYPVVSVQ 484
Query: 489 ESEIGLSLTQNRFLSTGTCKPDEDVTKWWVPLMPL---QGDYKVDFSGK-TTELPKTQFN 544
+ L L+Q+R+ G K D+ + W +P++ +G +++ G+ TT ++
Sbjct: 485 DCGSSLVLSQSRYSMLG--KSDDSL--WTIPVVVSWEGKGQERIELRGRETTVRKRSSVY 540
Query: 545 HFNANSFGFYRVKYDSDHLFQQQLQNLDKLSSRGKMGLISDV-----EVTECVKNLLTLI 599
NA GFYRV YDS L + +D LS ++ +I DV + +++ L I
Sbjct: 541 KVNAEYGGFYRVLYDSAGLSGLE-SRIDSLSVVDRVNVIEDVFGLGFGLYGGLEHGLRRI 599
Query: 600 SKFTNHQDPNDYYVWSIIFDTLNRMKSLLSSDKAVKKALDNFTLDLIQPSIEKLLEFLDQ 659
S++ + + Y+V + L R++S+ D + +D +I P + ++ F
Sbjct: 600 SEYYS----DSYHVARSGIEKLLRLRSVFYDDAEIVSLIDKKVRKMILPCVGRIDVFDIG 655
Query: 660 QKTNSFSKN 668
S S N
Sbjct: 656 TSVESVSMN 664
>ECU08g0070 [EO] KOG1046 Puromycin-sensitive aminopeptidase and related
aminopeptidases
Length = 864
Score = 322 bits (825), Expect = 2e-87
Identities = 215/669 (32%), Positives = 342/669 (50%), Gaps = 59/669 (8%)
Query: 17 HYEIELSELDAEHNSFIGSVRIIMSTVNANDMISLNMRDIEIVSAVVELKEGSVSLGMKD 76
HY++ + LDA F GSV I + I LN +++EI A + ++ + +
Sbjct: 38 HYDLHVKILDA---GFCGSVGIRVMISQDVSEIVLNAKELEIRDAGIVVEGARIPGRVVV 94
Query: 77 HSFDLENDVVSLKFPESISDDEFVLKIDYKGMIQTNMSGFYRSDYTDFVTGENKVMFSTQ 136
+ E +VV + FP S+ L +++ G + G Y+S G K ++ST
Sbjct: 95 GEAEKELEVVRIVFPSSLRAGPGYLTMEFCGDYNNGLVGLYKS-------GGPKEVYSTH 147
Query: 137 FEATDARRAFPCFDEPSLKATFDICIIAHEKYTVLANMPLKCTKKLTESDQISYRFHTTP 196
FE TDAR FPCFD+P +KATF I I A K+TVLAN + + D+ F T
Sbjct: 148 FEPTDARWVFPCFDQPDMKATFKISIDAGSKFTVLANTQAIPSLREEYGDRKIEYFEETC 207
Query: 197 LMSTYLVAWAVGEYDYIESETEKSIYPTIENYNTQDGTSSGCGKLPVKVYTAKGKAQQGK 256
MSTYLVA+ VGE YIE ++ + ++VY + + G+
Sbjct: 208 KMSTYLVAFVVGELSYIEDWSKDGVR--------------------LRVYGDSSEVEWGR 247
Query: 257 FALDVAKRVIDFFSESFEIPYPLP-----KLDLLCVETYSHNAMENFSLITFRPSALLY- 310
+ L+V KR +++FSE F + Y P K+D++ + +S AMEN+ LITFR +LLY
Sbjct: 248 YGLEVGKRCLEYFSEYFGVGYEFPRAGSAKIDMVGIPNFSSGAMENWGLITFRRESLLYV 307
Query: 311 DGNLDEPDAAALQKIAYVVSHEIAHQWFGNLVTMKWWDELWLNEGFATWIGYLAVEKF-- 368
G + D ++ +A V HE+ H WFGNLVTM WWD+LWLNEGFATW+ + +E
Sbjct: 308 PGKSNVED---MKNVAETVCHELGHMWFGNLVTMSWWDDLWLNEGFATWVSFKGMENIGS 364
Query: 369 FPDWDVPSMIMLQSHEVALELDSLKESHPIKVAVRNAKDIDQVFDSISYLKGCSILEMVS 428
WDV +L + + D L +SH I++ V + +I ++FDSISY KG S++ M+
Sbjct: 365 VVSWDVWGEFVLWNVVRGMVDDGLGKSHQIRMNVTDPGEIGEIFDSISYCKGASVIRMIE 424
Query: 429 GYLGQELFLKGVALYLKRNKFSNATMEDLFNCIGEVADIEVLERCKNWILTIGYPLVTVT 488
Y+G+ +F+ G+ Y+K + + N L+ IGE ++ E + WI GYP+V+V
Sbjct: 425 RYVGESVFMLGIRRYIKEHMYGNGNAMSLWKAIGEEYGEDISEMVEGWISQAGYPVVSVQ 484
Query: 489 ESEIGLSLTQNRFLSTGTCKPDEDVTKWWVPLMPL---QGDYKVDFSGK-TTELPKTQFN 544
+ L L+Q+R+ G K D+ + W +P++ +G +++ G+ TT ++
Sbjct: 485 DCGSSLVLSQSRYSMLG--KSDDSL--WTIPVVVSWEGKGQERIELRGRETTVRKRSSVY 540
Query: 545 HFNANSFGFYRVKYDSDHLFQQQLQNLDKLSSRGKMGLISDV-----EVTECVKNLLTLI 599
NA GFYRV YDS L + +D LS ++ +I DV + +++ L I
Sbjct: 541 KVNAEYGGFYRVLYDSAGLSGLE-SRIDSLSVVDRVNVIEDVFGLGFGLYGGLEHGLRRI 599
Query: 600 SKFTNHQDPNDYYVWSIIFDTLNRMKSLLSSDKAVKKALDNFTLDLIQPSIEKLLEFLDQ 659
S++ + + Y+V + L R++S+ D + +D +I P + ++ F
Sbjct: 600 SEYYS----DSYHVARSGIEKLLRLRSVFYDDAEIVSLIDKKVRKMILPCVGRIDVFDIG 655
Query: 660 QKTNSFSKN 668
S S N
Sbjct: 656 TSVESVSMN 664
>Hs20534524 [EO] KOG1046 Puromycin-sensitive aminopeptidase and related
aminopeptidases
Length = 957
Score = 313 bits (801), Expect = 1e-84
Identities = 248/908 (27%), Positives = 411/908 (44%), Gaps = 91/908 (10%)
Query: 9 LPTDFRANHYEIELSELDAEHNSFIGSVRIIMSTVNANDMISLNMRDIEIVSAVVELKEG 68
LP HY++ + L E +++ G+V I ++ + L++R+ I + + ELK
Sbjct: 93 LPDFVNPVHYDLHVKPL-LEEDTYTGTVSISINLSAPTRYLWLHLRETRI-TRLPELKRP 150
Query: 69 SVSLGMKDHSFDLEN-DVVSLKFPESIS----DDEFVLKIDYKGMIQTNMSGFYRSDYTD 123
S F+ + + V ++ E ++ D ++L +++ G + ++ GFYR+ YT+
Sbjct: 151 SGDQVQVRRCFEYKKQEYVVVEAEEELTPSSGDGLYLLTMEFAGWLNGSLVGFYRTTYTE 210
Query: 124 FVTGENKVMFSTQFEATDARRAFPCFDEPSLKATFDICIIAHEKYTVLANMPLKCTKKLT 183
G+ K + +T E TDAR++FPCFDEP+ KAT+ I I ++Y L+NMP+ ++
Sbjct: 211 --NGQVKSIVATDHEPTDARKSFPCFDEPNKKATYTISITHPKEYGALSNMPV-AKEESV 267
Query: 184 ESDQISYRFHTTPLMSTYLVAWAVGEYDYIESETEKSIYPTIENYNTQDGTSSGCGKLPV 243
+ F + MSTYLV +AV ++D ++ S GK P+
Sbjct: 268 DDKWTRTTFEKSVPMSTYLVCFAVHQFDSVKR-------------------ISNSGK-PL 307
Query: 244 KVYTAKGKAQQGKFALDVAKRVIDFFSESFEIPYPLPKLDLLCVETYSHNAMENFSLITF 303
+Y + ++A ++ K V D+F E F + Y LPKLD + + + AMEN+ LIT+
Sbjct: 308 TIYVQPEQKHTAEYAANITKSVFDYFEEYFAMNYSLPKLDKIAIPDFGTGAMENWGLITY 367
Query: 304 RPSALLYDGNLDEPDAAALQKIAYVVSHEIAHQWFGNLVTMKWWDELWLNEGFATWIGYL 363
R + LLYD E ++ Q++A VV+HE+ HQWFGN+VTM WW++LWLNEGFA++ +L
Sbjct: 368 RETNLLYDPK--ESASSNQQRVATVVAHELVHQWFGNIVTMDWWEDLWLNEGFASFFEFL 425
Query: 364 AVEKFFPDWDVPSMIMLQSHEVALELDSLKESHPIKVAVRNAKDIDQVFDSISYLKGCSI 423
V DW + ++L+ E DSL SHPI V V +I VFD ISY KG SI
Sbjct: 426 GVNHAETDWQMRDQMLLEDVLPVQEDDSLMSSHPIIVTVTTPDEITSVFDGISYSKGSSI 485
Query: 424 LEMVSGYLGQELFLKGVALYLKRNKFSNATMEDLFNCIGEVADIEVLERCKNWILTIGYP 483
L M+ ++ E F KG +YL++ +F NA D + + E + + V E W +GYP
Sbjct: 486 LRMLEDWIKPENFQKGCQMYLEKYQFKNAKTSDFWAALEEASRLPVKEVMDTWTRQMGYP 545
Query: 484 LVTVTESEIGLSLTQNRFLSTGTCKPDEDVT----KWWVPLMPLQGDY-------KVDFS 532
++ V + ++TQ RFL P + + W +P+ + + + +
Sbjct: 546 VLNVNGVK---NITQKRFLLDPRANPSQPPSDLGYTWNIPVKWTEDNITSSVLFNRSEKE 602
Query: 533 GKTTELPKTQFNHF---NANSFGFYRVKYDS---DHLFQQQLQNLDKLSSRGKMGLISDV 586
G T N F N + GFYRV Y+ D + N SS + LI D
Sbjct: 603 GITLNSSNPSGNAFLKINPDHIGFYRVNYEVATWDSIATALSLNHKTFSSADRASLIDDA 662
Query: 587 EVTECVK----NLLTLISKFTNHQDPNDYYVWSIIFDTLNRMKSLLSSDKAVKKALDNFT 642
+ + ++K+ ++ ++ W + + + S+ DK
Sbjct: 663 FALARAQLLDYKVALNLTKYLKREE--NFLPWQRVISAVTYIISMFEDDKE--------- 711
Query: 643 LDLIQPSIEKLLEFLDQQKTNSFSKNPDNFLSNQFFELMALG-AGTASHPETVAKCREMF 701
+ P IE+ + + +S N + LG A E + +F
Sbjct: 712 ---LYPMIEEYFQGQVKPIADSLGWNDAGDHVTKLLRSSVLGFACKMGDREALNNASSLF 768
Query: 702 ESKSYSPVFRNVLLQII-----LSQPDXXXXXXXXXXXXXXXSTLVYKESLLTALGKIKN 756
E V V L+++ + S KE LL L +KN
Sbjct: 769 EQWLNGTVSLPVNLRLLVYRYGMQNSGNEISWNYTLEQYQKTSLAQEKEKLLYGLASVKN 828
Query: 757 AELFDTVLNLLL---IIEPMDVQFLATSLGSNYAIRTKLWNFIKTNYVKLHERLAINTVV 813
L L+LL +I+ DV + + N + WN+I+ N+ L R +N
Sbjct: 829 VTLLSRYLDLLKDTNLIKTQDVFTVIRYISYNSYGKNMAWNWIQLNWDYLVNRYTLNNRN 888
Query: 814 IDRFLRFSMKDLMGEDVKTDYEL-----FFADKNMEGFDRGVR-QTLERIEKNTRYFETN 867
+ R + + E T+ +L FFA G R Q LE ++ N + + +
Sbjct: 889 LGRIV------TIAEPFNTELQLWQMESFFAKYPQAGAGEKPREQVLETVKNNIEWLKQH 942
Query: 868 LSLVKEYF 875
+ ++E+F
Sbjct: 943 RNTIREWF 950
>Hs4502095 [EO] KOG1046 Puromycin-sensitive aminopeptidase and related
aminopeptidases
Length = 967
Score = 312 bits (800), Expect = 1e-84
Identities = 231/833 (27%), Positives = 404/833 (47%), Gaps = 92/833 (11%)
Query: 94 ISDDEFVLKIDYKGMIQTNMSGFYRSDYTDFVTGENKVMFSTQFEATDARRAFPCFDEPS 153
+ D ++ + +++G + +++GFYRS+Y + KV+ +TQ +A DAR++FPCFDEP+
Sbjct: 171 VKDSQYEMDSEFEGELADDLAGFYRSEYME--GNVRKVVATTQMQAADARKSFPCFDEPA 228
Query: 154 LKATFDICIIAHEKYTVLANM-PLKCTKKLTESDQISY-RFHTTPLMSTYLVAWAVGEYD 211
+KA F+I +I + T L+NM P + L E + FHTTP MSTYL+A+ V E+D
Sbjct: 229 MKAEFNITLIHPKDLTALSNMLPKGPSTPLPEDPNWNVTEFHTTPKMSTYLLAFIVSEFD 288
Query: 212 YIESETEKSIYPTIENYNTQDGTSSGCGKLPVKVYTAKGKAQQGKFALDVAKRVIDFFSE 271
Y+E + + I + ++G G +AL+V +++FF+
Sbjct: 289 YVEKQASNGVL--IRIWARPSAIAAG----------------HGDYALNVTGPILNFFAG 330
Query: 272 SFEIPYPLPKLDLLCVETYSHNAMENFSLITFRPSALLYDGNLDEPDAAALQKIAYVVSH 331
++ PYPLPK D + + ++ AMEN+ L+T+R ++LL+D ++ +++ V++H
Sbjct: 331 HYDTPYPLPKSDQIGLPDFNAGAMENWGLVTYRENSLLFDPL--SSSSSNKERVVTVIAH 388
Query: 332 EIAHQWFGNLVTMKWWDELWLNEGFATWIGYLAVEKFFPDWDVPSMIMLQSHEVALELDS 391
E+AHQWFGNLVT++WW++LWLNEGFA+++ YL + P W++ +++L + +D+
Sbjct: 389 ELAHQWFGNLVTIEWWNDLWLNEGFASYVEYLGADYAEPTWNLKDLMVLNDVYRVMAVDA 448
Query: 392 LKESHPIKV---AVRNAKDIDQVFDSISYLKGCSILEMVSGYLGQELFLKGVALYLKRNK 448
L SHP+ + I ++FD+ISY KG S+L M+S +L +++F +G+A YL
Sbjct: 449 LASSHPLSTPASEINTPAQISELFDAISYSKGASVLRMLSSFLSEDVFKQGLASYLHTFA 508
Query: 449 FSNATMEDLFNCIGEVAD-------IEVLERCKNWILTIGYPLVTVTESEIGLSLTQNRF 501
+ N +L++ + E + V + W L +G+P++TV S +L+Q F
Sbjct: 509 YQNTIYLNLWDHLQEAVNNRSIQLPTTVRDIMNRWTLQMGFPVITVDTST--GTLSQEHF 566
Query: 502 L---STGTCKPDEDVTKWWVPLMPL-----QGDYKVDFSGKTTELPKTQFNHF---NANS 550
L + +P E W VP+ + Q DY + +L T N + N N
Sbjct: 567 LLDPDSNVTRPSEFNYVWIVPITSIRDGRQQQDYWLIDVRAQNDLFSTSGNEWVLLNLNV 626
Query: 551 FGFYRVKYDSDH--LFQQQLQ-NLDKLSSRGKMGLISD---------VEVTECVKNLLTL 598
G+YRV YD ++ Q QLQ + + + +I+D V VT + N L L
Sbjct: 627 TGYYRVNYDEENWRKIQTQLQRDHSAIPVINRAQIINDAFNLASAHKVPVTLALNNTLFL 686
Query: 599 ISKFTNHQDPNDYYVWSIIFDTLNRMKSLLSSDKAVKKALDNFTLDLIQPSIEKLLEFLD 658
I + Y W +L+ K L+ V + N+ + P L
Sbjct: 687 I-------EERQYMPWEAALSSLSYFK-LMFDRSEVYGPMKNYLKKQVTP-----LFIHF 733
Query: 659 QQKTNSFSKNPDNFLSNQFFELMALGAGTASHPETVAKCREM--------FESKSYSPVF 710
+ TN++ + P+N L +Q+ E+ A+ ++ V +C EM E+ + +P+
Sbjct: 734 RNNTNNWREIPEN-LMDQYSEVNAISTACSN---GVPECEEMVSGLFKQWMENPNNNPIH 789
Query: 711 RNVLLQIILSQ-PDXXXXXXXXXXXXXXXSTLVYK-ESLLTALGKIKNAELFDTVLNLLL 768
N+ + + +TLV + + L AL K + + L+ L
Sbjct: 790 PNLRSTVYCNAIAQGGEEEWDFAWEQFRNATLVNEADKLRAALACSKELWILNRYLSYTL 849
Query: 769 ---IIEPMDVQFLATSLGSNYAIRTKLWNFIKTNYVKLHERLAINTVVIDRFLRFSMKDL 825
+I D S+ +N + +W+F+++N+ KL + ++ +
Sbjct: 850 NPDLIRKQDATSTIISITNNVIGQGLVWDFVQSNWKKLFNDYGGGSFSFSNLIQAVTRRF 909
Query: 826 MGEDVKTDYELFFADKNMEGFDRGVR---QTLERIEKNTRYFETNLSLVKEYF 875
E E F D GF G R Q LE+ + N ++ + N +V ++F
Sbjct: 910 STEYELQQLEQFKKDNEETGFGSGTRALEQALEKTKANIKWVKENKEVVLQWF 962
>Hs4503575 [EO] KOG1046 Puromycin-sensitive aminopeptidase and related
aminopeptidases
Length = 957
Score = 311 bits (798), Expect = 2e-84
Identities = 248/908 (27%), Positives = 410/908 (44%), Gaps = 91/908 (10%)
Query: 9 LPTDFRANHYEIELSELDAEHNSFIGSVRIIMSTVNANDMISLNMRDIEIVSAVVELKEG 68
LP HY++ + L E +++ G+V I ++ + L++R+ I + + ELK
Sbjct: 93 LPDFVNPVHYDLHVKPL-LEEDTYTGTVSISINLSAPTRYLWLHLRETRI-TRLPELKRP 150
Query: 69 SVSLGMKDHSFDLEN-DVVSLKFPESIS----DDEFVLKIDYKGMIQTNMSGFYRSDYTD 123
S F+ + + V ++ E ++ D ++L +++ G + ++ GFYR+ YT+
Sbjct: 151 SGDQVQVRRCFEYKKQEYVVVEAEEELTPSSGDGLYLLTMEFAGWLNGSLVGFYRTTYTE 210
Query: 124 FVTGENKVMFSTQFEATDARRAFPCFDEPSLKATFDICIIAHEKYTVLANMPLKCTKKLT 183
G K + +T E TDAR++FPCFDEP+ KAT+ I I ++Y L+NMP+ ++
Sbjct: 211 --NGRVKSIAATDHEPTDARKSFPCFDEPNKKATYTISITHPKEYGALSNMPV-AKEESV 267
Query: 184 ESDQISYRFHTTPLMSTYLVAWAVGEYDYIESETEKSIYPTIENYNTQDGTSSGCGKLPV 243
+ F + MSTYLV +AV ++D ++ S GK P+
Sbjct: 268 DDKWTRTTFEKSVPMSTYLVCFAVHQFDSVKR-------------------ISNSGK-PL 307
Query: 244 KVYTAKGKAQQGKFALDVAKRVIDFFSESFEIPYPLPKLDLLCVETYSHNAMENFSLITF 303
+Y + ++A ++ K V D+F E F + Y LPKLD + + + AMEN+ LIT+
Sbjct: 308 TIYVQPEQKHTAEYAANITKSVFDYFEEYFAMNYSLPKLDKIAIPDFGTGAMENWGLITY 367
Query: 304 RPSALLYDGNLDEPDAAALQKIAYVVSHEIAHQWFGNLVTMKWWDELWLNEGFATWIGYL 363
R + LLYD E ++ Q++A VV+HE+ HQWFGN+VTM WW++LWLNEGFA++ +L
Sbjct: 368 RETNLLYDPK--ESASSNQQRVATVVAHELVHQWFGNIVTMDWWEDLWLNEGFASFFEFL 425
Query: 364 AVEKFFPDWDVPSMIMLQSHEVALELDSLKESHPIKVAVRNAKDIDQVFDSISYLKGCSI 423
V DW + ++L+ E DSL SHPI V V +I VFD ISY KG SI
Sbjct: 426 GVNHAETDWQMRDQMLLEDVLPVQEDDSLMSSHPIIVTVTTPDEITSVFDGISYSKGSSI 485
Query: 424 LEMVSGYLGQELFLKGVALYLKRNKFSNATMEDLFNCIGEVADIEVLERCKNWILTIGYP 483
L M+ ++ E F KG +YL++ +F NA D + + E + + V E W +GYP
Sbjct: 486 LRMLEDWIKPENFQKGCQMYLEKYQFKNAKTSDFWAALEEASRLPVKEVMDTWTRQMGYP 545
Query: 484 LVTVTESEIGLSLTQNRFLSTGTCKPDEDVT----KWWVPLMPLQGDY-------KVDFS 532
++ V + ++TQ RFL P + + W +P+ + + + +
Sbjct: 546 VLNVNGVK---NITQKRFLLDPRANPSQPPSDLGYTWNIPVKWTEDNITSSVLFNRSEKE 602
Query: 533 GKTTELPKTQFNHF---NANSFGFYRVKYDS---DHLFQQQLQNLDKLSSRGKMGLISDV 586
G T N F N + GFYRV Y+ D + N SS + LI D
Sbjct: 603 GITLNSSNPSGNAFLKINPDHIGFYRVNYEVATWDSIATALSLNHKTFSSADRASLIDDA 662
Query: 587 EVTECVK----NLLTLISKFTNHQDPNDYYVWSIIFDTLNRMKSLLSSDKAVKKALDNFT 642
+ + ++K+ ++ ++ W + + + S+ DK
Sbjct: 663 FALARAQLLDYKVALNLTKYLKREE--NFLPWQRVISAVTYIISMFEDDKE--------- 711
Query: 643 LDLIQPSIEKLLEFLDQQKTNSFSKNPDNFLSNQFFELMALG-AGTASHPETVAKCREMF 701
+ P IE+ + + +S N + LG A E + +F
Sbjct: 712 ---LYPMIEEYFQGQVKPIADSLGWNDAGDHVTKLLRSSVLGFACKMGDREALNNASSLF 768
Query: 702 ESKSYSPVFRNVLLQII-----LSQPDXXXXXXXXXXXXXXXSTLVYKESLLTALGKIKN 756
E V V L+++ + S KE LL L +KN
Sbjct: 769 EQWLNGTVSLPVNLRLLVYRYGMQNSGNEISWNYTLEQYQKTSLAQEKEKLLYGLASVKN 828
Query: 757 AELFDTVLNLLL---IIEPMDVQFLATSLGSNYAIRTKLWNFIKTNYVKLHERLAINTVV 813
L L+LL +I+ DV + + N + WN+I+ N+ L R +N
Sbjct: 829 VTLLSRYLDLLKDTNLIKTQDVFTVIRYISYNSYGKNMAWNWIQLNWDYLVNRYTLNNRN 888
Query: 814 IDRFLRFSMKDLMGEDVKTDYEL-----FFADKNMEGFDRGVR-QTLERIEKNTRYFETN 867
+ R + + E T+ +L FFA G R Q LE ++ N + + +
Sbjct: 889 LGRIV------TIAEPFNTELQLWQMESFFAKYPQAGAGEKPREQVLETVKNNIEWLKQH 942
Query: 868 LSLVKEYF 875
+ ++E+F
Sbjct: 943 RNTIREWF 950
>Hs11641261 [EO] KOG1046 Puromycin-sensitive aminopeptidase and related
aminopeptidases
Length = 960
Score = 306 bits (783), Expect = 1e-82
Identities = 259/936 (27%), Positives = 426/936 (44%), Gaps = 113/936 (12%)
Query: 9 LPTDFRANHYEI----ELSELDAEHNSFIGSVRIIMSTVNANDMISLNMRDIEIVSAVVE 64
LP+ HY++ L+ LD F+ S +I + NA I L+ +D+EI +A ++
Sbjct: 69 LPSVVIPLHYDLFVHPNLTSLD-----FVASEKIEVLVSNATQFIILHSKDLEITNATLQ 123
Query: 65 LKEGSVSLG----MKDHSFDLENDVVSLKFPESISDD-EFVLKIDYKGMIQTNMSGFYRS 119
+E S + +K S+ ++ ++L PE ++ ++ + +D++ + GFY+S
Sbjct: 124 SEEDSRYMKPGKELKVLSYPA-HEQIALLVPEKLTPHLKYYVAMDFQAKLGDGFEGFYKS 182
Query: 120 DYTDFVTGENKVMFSTQFEATDARRAFPCFDEPSLKATFDICIIAHEKYTVLANMPLKCT 179
Y + GE +++ T FE T AR AFPCFDEP KA F I I ++ L+NMP T
Sbjct: 183 TYRT-LGGETRILAVTDFEPTQARMAFPCFDEPLFKANFSIKIRRESRHIALSNMPKVKT 241
Query: 180 KKLTESDQISYRFHTTPLMSTYLVAWAVGEYDYIESETEKSIYPTIENYNTQDGTSSGCG 239
+L E + F TT MSTYLVA+ V ++ ++ TSSG
Sbjct: 242 IEL-EGGLLEDHFETTVKMSTYLVAYIVCDF-----------------HSLSGFTSSG-- 281
Query: 240 KLPVKVYTAKGKAQQGKFALDVAKRVIDFFSESFEIPYPLPKLDLLCVETYSHNAMENFS 299
+ V +Y + K Q +AL + +++DF+ + F+I YPL KLDL+ + ++ AMEN+
Sbjct: 282 -VKVSIYASPDKRNQTHYALQASLKLLDFYEKYFDIYYPLSKLDLIAIPDFAPGAMENWG 340
Query: 300 LITFRPSALLYDGNLDEPDAAALQKIAYVVSHEIAHQWFGNLVTMKWWDELWLNEGFATW 359
LIT+R ++LL+D A+ + V++HE+AHQWFGNLVTM+WW+++WL EGFA +
Sbjct: 341 LITYRETSLLFDPKTSS--ASDKLWVTRVIAHELAHQWFGNLVTMEWWNDIWLKEGFAKY 398
Query: 360 IGYLAVEKFFPDWDVPSMIMLQSHEVALELDSLKESHPIKVAVRNAKDIDQVFDSISYLK 419
+ +AV +P+ + EV + DSL S PI I ++FD +SY K
Sbjct: 399 MELIAVNATYPELQFDDYFLNVCFEVITK-DSLNSSRPISKPAETPTQIQEMFDEVSYNK 457
Query: 420 GCSILEMVSGYLGQELFLKGVALYLKRNKFSNATMEDLFNCIGEVA-------------- 465
G IL M+ +LG+E F KG+ YLK+ + NA +DL++ +
Sbjct: 458 GACILNMLKDFLGEEKFQKGIIQYLKKFSYRNAKNDDLWSSLSNSCLESDFTSGGVCHSD 517
Query: 466 -------------DIEVLERCKNWILTIGYPLVTVTESEIGLSLTQNRFLSTGTCKPD-- 510
+ EV E W L G PL+ V + L L Q RFL G + D
Sbjct: 518 PKMTSNMLAFLGENAEVKEMMTTWTLQKGIPLLVVKQDGCSLRLQQERFLQ-GVFQEDPE 576
Query: 511 ----EDVTKWWVPLMPLQGDYKV------DFSGKTTELP-KTQFNHFNANSFGFYRVKYD 559
++ W +PL V T +LP KT + FN +S G+Y V Y+
Sbjct: 577 WRALQERYLWHIPLTYSTSSSNVIHRHILKSKTDTLDLPEKTSWVKFNVDSNGYYIVHYE 636
Query: 560 S---DHLFQQQLQNLDKLSSRGKMGLISDVEVTECVKNLLTL-----ISKFTNHQDPNDY 611
D L Q QN L + ++GLI DV LTL ++ + H+ +
Sbjct: 637 GHGWDQLITQLNQNHTLLRPKDRVGLIHDV-FQLVGAGRLTLDKALDMTYYLQHETSSPA 695
Query: 612 YV--WSIIFDTLNRMKSLLSSDKAVKKALDNFTLDLIQPSIEKLLEFLDQQKTNSFSKNP 669
+ S + + M SD + + L + L +P I D+Q +
Sbjct: 696 LLEGLSYLESFYHMMDRRNISD--ISENLKRYLLQYFKPVI-------DRQSWSDKGSVW 746
Query: 670 DNFLSNQFFELMALGAGTASHPETVAKCREMFESKSYSPVFRNV---LLQIILSQPDXXX 726
D L + +L A +H + K E+F S N+ +L+I+ S
Sbjct: 747 DRMLRSALLKL----ACDLNHAPCIQKAAELFSQWMESSGKLNIPTDVLKIVYSVGAQTT 802
Query: 727 XXXXXXXXXXXXS-TLVYKESLLTALGKIKNAELFDTVLNLLL---IIEPMDVQFLATSL 782
S + + +L AL K+ E ++ L + +I+ ++ L ++
Sbjct: 803 AGWNYLLEQYELSMSSAEQNKILYALSTSKHQEKLLKLIELGMEGKVIKTQNLAALLHAI 862
Query: 783 GSNYAIRTKLWNFIKTNYVKLHERLAINTVVIDRFLRFSMKDLMGEDVKTDYELFFADKN 842
+ W+F++ N+ L ++ + + I + + +D + +LFF
Sbjct: 863 ARRPKGQQLAWDFVRENWTHLLKKFDLGSYDIRMIISGTTAHFSSKDKLQEVKLFFESLE 922
Query: 843 MEGFDRGVRQT-LERIEKNTRYFETNLSLVKEYFKI 877
+G + QT LE I KN ++ E NL ++ + +
Sbjct: 923 AQGSHLDIFQTVLETITKNIKWLEKNLPTLRTWLMV 958
>7301751 [EO] KOG1046 Puromycin-sensitive aminopeptidase and related
aminopeptidases
Length = 1017
Score = 303 bits (775), Expect = 1e-81
Identities = 243/932 (26%), Positives = 429/932 (45%), Gaps = 115/932 (12%)
Query: 9 LPTDFRANHYEIELSELDAEHNSFIGSVRIIMSTVNANDMISLNMRDIEIVSAVVELK-- 66
LP R Y I + + + +F GSV+I + + I+++ ++ I + +
Sbjct: 132 LPHSIRPLKYNITIEPQLSGNFTFAGSVQIRIRVLEDCYNITMHAEELNISRSDASVHRV 191
Query: 67 ------EGSVSLGMKDHSFDLENDVVSLKFPESISDDEFVLKIDYKGMIQTNMSGFYRSD 120
EG K + + V + + + D E+V+ + + G+I+ + GFYRS
Sbjct: 192 QNNGEPEGDGLRIHKQYLVGAKQFFVIELYDKLLKDVEYVVHLRFDGIIEDYLQGFYRSS 251
Query: 121 YTDFVTGENKVMFSTQFEATDARRAFPCFDEPSLKATFDICIIAHEKYTVLANMPLKCTK 180
Y V E + + STQF+ATDARRAFPCFDEP+LKA F + I T ++NMP+ +
Sbjct: 252 YE--VHNETRWVASTQFQATDARRAFPCFDEPALKANFTLHIARPRNMTTISNMPIVSSN 309
Query: 181 K-LTESDQISYRFHTTPLMSTYLVAWAVGEYDYIESETEKSIYPTIENYNTQDGTSSGCG 239
T + F + MSTYLVA+A+ ++ +I S
Sbjct: 310 DHATMPSYVWDHFAESLPMSTYLVAYAISDFTHISSGN---------------------- 347
Query: 240 KLPVKVYTAKGKAQQGKFALDVAKRVIDFFSESFEIPYPLPKLDLLCVETYSHNAMENFS 299
V+ + ++AL V R++ F + F + +PLPK+D++ + + AMEN+
Sbjct: 348 ---FAVWARADAIKSAEYALSVGPRILTFLQDFFNVTFPLPKIDMIALPEFQAGAMENWG 404
Query: 300 LITFRPSALLYDGNLDEPDAAALQKIAYVVSHEIAHQWFGNLVTMKWWDELWLNEGFATW 359
LITFR +A+LYD + A Q++A VV HE+AHQWFGNLVT WW ++WLNEGFA++
Sbjct: 405 LITFRETAMLYDPGV--ATANNKQRVASVVGHELAHQWFGNLVTPSWWSDIWLNEGFASY 462
Query: 360 IGYLAVEKFFPDWDVPSMIMLQSHEVALELDSLKESHPIKVAVRNAKDIDQVFDSISYLK 419
+ YL + P+W ++ + +LD+L SH I V N ++I ++FD ISY K
Sbjct: 463 MEYLTADAVAPEWKQLDQFVVNELQAVFQLDALSTSHKISHEVFNPQEISEIFDRISYAK 522
Query: 420 GCSILEMVSGYLGQELFLKGVALYLKRNKFSNATMEDLFNCIGEVA--------DIEVLE 471
G +I+ M++ +L +F +G++ YL+ +++AT +DL++ + A V E
Sbjct: 523 GSTIIRMMAHFLTNPIFRRGLSKYLQEMAYNSATQDDLWHFLTVEAKSSGLLDDSRSVKE 582
Query: 472 RCKNWILTIGYPLVTVT---ESEIGLSLTQNRFLSTGTCKPDEDVTKWWVPLMPLQGDYK 528
W L GYP+V V+ S++ + L Q RF+ T T + DE + W++P+ D +
Sbjct: 583 IMDTWTLQTGYPVVKVSRHPNSDV-IRLEQVRFVYTNTTREDESLL-WYIPI-TFTTDSE 639
Query: 529 VDFSG--KTTELPKTQFNH-------------FNANSFGFYRVKYD-------SDHLFQQ 566
++F+ TT +P+T+ FN G+YRV YD ++HL
Sbjct: 640 LNFANTRPTTWMPRTKLYELENRELSLAKWFIFNVQQTGYYRVNYDLENWMAITEHL--M 697
Query: 567 QLQNLDKLSSRGKMGLISDVE--------VTECVKNLLTLISKFTNHQDPNDYYVWSIIF 618
+ N + ++ + LI DV E NL +++ H+ + W
Sbjct: 698 DVDNFEDIAPANRAQLIDDVMNLARGSYLSYETAMNL----TRYLGHE--LGHVPWKAAI 751
Query: 619 DTLNRMKSLLSSDKAVKKALDNFTLDLIQPSIEKLLEFLDQQK--TNSFSKNPDNFLSNQ 676
+ S+ +++ DL++ + K L+ + Q +S ++ D + +
Sbjct: 752 SNFIFIDSMF---------VNSGDYDLLKNYLLKQLKKVYDQVGFKDSQDESEDILVKLK 802
Query: 677 FFELMALGAGTASHPETVAKCREMFES-------KSYSPVFRNVLLQIILSQPDXXXXXX 729
+++++ A H E +A+ F++ S +P+ N+ + S
Sbjct: 803 RADILSM-ACHLGHQECIAEASRHFQNWMQTPNPDSNNPIVPNLRGVVYCSAIQYGTEYE 861
Query: 730 XXXXXXXXXSTLV--YKESLLTALGKIKNAELFDTVLNLLLI---IEPMDVQFLATSLGS 784
T V K+ LL ALG K L L + I D+ + ++ +
Sbjct: 862 WDFAFERFLKTNVPGEKDLLLNALGCSKEPWLLYRFLRRGISGQHIRKQDLFRVFAAVST 921
Query: 785 NYAIRTKLWNFIKTNYVKLHERLAINTVVIDRFLRFSMKDLMGEDVKTDYELFFADKNME 844
+ ++F++ N+ ++ + I +F+ K + ++E F D + +
Sbjct: 922 TVVGQNIAFDFLRNNWQEIKTYMGSQMSSIHTLFKFATKGFNSKFQLGEFENFVKDAHWD 981
Query: 845 GFDRGVRQTLERIEKNTRYFETNLSLVKEYFK 876
+DR V+Q +E IE + + N + + +
Sbjct: 982 -YDRPVQQIVEHIETSVDWMNKNYKSIVRWLE 1012
>7299747 [EO] KOG1046 Puromycin-sensitive aminopeptidase and related
aminopeptidases
Length = 985
Score = 302 bits (774), Expect = 1e-81
Identities = 194/647 (29%), Positives = 323/647 (48%), Gaps = 75/647 (11%)
Query: 9 LPTDFRANHYEIELSELDAEHNSFIGSVRIIMSTVNANDMISLNMRDIEIVSAVVELKEG 68
LP + + Y + L D E ++ G++ I + + I ++++ + + + V+ +
Sbjct: 144 LPKQIKPSKYRLHLRP-DLERKNYSGNISISLQVLEPIAFIPVHVKQLNVSTVEVKRLDE 202
Query: 69 SVSLGMKDHSFDL-----ENDVVSLKFPESISDDEFVLKIDYKGMIQTNMSGFYRSDYTD 123
S +KD + L E + +F + + + L +++ G + ++G Y+S Y D
Sbjct: 203 S-GAPLKDITPTLTFAHPEFEYWVTEFEQPLEAGNYSLLLNFTGSLVDRITGMYQSSYLD 261
Query: 124 FVTGENKVMFSTQFEATDARRAFPCFDEPSLKATFDICII--AHEKYTVLANMPLKCTKK 181
+ ++ + ST+FE T AR+AFPCFDEP+LKA F I + + ++Y VL+NMP+ +
Sbjct: 262 KLKNRSRSIISTKFEPTYARQAFPCFDEPALKAQFTITVARPSGDEYHVLSNMPV--ASE 319
Query: 182 LTESDQISYRFHTTPLMSTYLVAWAVGEYDYIESETEKSIYPTIENYNTQDGTSSGCGKL 241
+ D F T MSTYL A+ V ++ Y E+ T +GTS +
Sbjct: 320 YVDGDITEVTFAETVPMSTYLAAFVVSDFQYKET--------------TVEGTS-----I 360
Query: 242 PVKVYTAKGKAQQGKFALDVAKRVIDFFSESFEIPYPLPKLDLLCVETYSHNAMENFSLI 301
+KVY + ++ ++ALD A V+ ++ F + Y LPKLDL+ + + AMEN+ L+
Sbjct: 361 ALKVYAPPAQVEKTQYALDTAAGVMAYYINYFNVSYALPKLDLVAIPDFVSGAMENWGLV 420
Query: 302 TFRPSALLYDGNLDEPDAAALQKIAYVVSHEIAHQWFGNLVTMKWWDELWLNEGFATWIG 361
TFR +ALLYD + + Q++A VV+HE+AHQWFGNLVTM WW++LWLNEGFA+++
Sbjct: 421 TFRETALLYDESTSS--SVNKQRVAIVVAHELAHQWFGNLVTMNWWNDLWLNEGFASFLE 478
Query: 362 YLAVEKFFPDWDVPSMIMLQSHEVALELDSLKESHPIKVAVRNAKDIDQVFDSISYLKGC 421
Y V++ P+WD+ + +++ L +D+ SHPI ++ + +I + FD+I+Y KG
Sbjct: 479 YKGVKQMHPEWDMDNQFVIEELHPVLTIDATLASHPIVKSIESPAEITEYFDTITYSKGA 538
Query: 422 SILEMVSGYLGQELFLKGVALYLKRNKFSNATMEDLFNCIGEVADIE--VLERCKNWILT 479
+++ M+ +G+E YL R+ +S AT ED + E +E V + + W
Sbjct: 539 ALVRMLENLVGEEKLRNATTRYLVRHIYSTATTEDYLTAVEEEEGLEFDVKQIMQTWTEQ 598
Query: 480 IGYPLVTVTESEIGLSLTQNRFLS-----TGTCKPDEDVTKWWVPLMPLQGDYKVDFSGK 534
+G P+V V +S LTQ RFL+ + +W +P+ S
Sbjct: 599 MGLPVVEVEKSGSTYKLTQKRFLANEDDYAAEAEASSFNYRWSIPI--------TYTSSI 650
Query: 535 TTELPKTQFNH-----------------FNANSFGFYRVKYDSD---HLFQQQLQNLDKL 574
+E+ FNH N N G+YRV Y S+ L + +
Sbjct: 651 NSEVQSLIFNHNDNEATITLPEEASWIKINTNQVGYYRVNYGSEQWAELISALKNSRETF 710
Query: 575 SSRGKMGLISDVEVTECVKNL-----LTLISKFTNHQDPNDYYVWSI 616
S+ + L++D L L LIS + Q DY WS+
Sbjct: 711 STADRAHLLNDANTLAAAGQLNYSVALDLISYLESEQ---DYVPWSV 754
>Hs5031881 [EO] KOG1046 Puromycin-sensitive aminopeptidase and related
aminopeptidases
Length = 1025
Score = 298 bits (762), Expect = 3e-80
Identities = 202/601 (33%), Positives = 305/601 (50%), Gaps = 56/601 (9%)
Query: 9 LPTDFRANHYEIELSELDAEHNSFIGSVRIIMSTVNANDMISL-----NMRDIEIVSAVV 63
LPT YE+ L + +F GSV I + + I L N+ + +SAV
Sbjct: 168 LPTAVVPLRYELSLHP-NLTSMTFRGSVTISVQALQVTWNIILHSTGHNISRVTFMSAVS 226
Query: 64 ELKEGSVSLGMKDHSFDLENDVVSLKFPESI-SDDEFVLKIDYKGMIQTNMSGFYRSDYT 122
++ + L H +++ PE++ + + LKI+Y I ++ GFY YT
Sbjct: 227 SQEKQAEILEYAYHG------QIAIVAPEALLAGHNYTLKIEYSANISSSYYGFYGFSYT 280
Query: 123 DFVTGENKVMFSTQFEATDARRAFPCFDEPSLKATFDICIIAHEKYTVLANMPLKCTKKL 182
D + E K +TQFE AR AFPCFDEP+ KATF I II E+YT L+NMP K + L
Sbjct: 281 D-ESNEKKYFAATQFEPLAARSAFPCFDEPAFKATFIIKIIRDEQYTALSNMPKKSSVVL 339
Query: 183 TESDQISYRFHTTPLMSTYLVAWAVGEYDYIESETEKSIYPTIENYNTQDGTSSGCGKLP 242
+ + F + MSTYLVA+ VGE + + ++
Sbjct: 340 DDG-LVQDEFSESVKMSTYLVAFIVGEMKNLSQDVNGTL--------------------- 377
Query: 243 VKVYTAKGKAQQGKFALDVAKRVIDFFSESFEIPYPLPKLDLLCVETYSHNAMENFSLIT 302
V +Y Q +AL+ ++++FF FEI YPL KLDL+ + + AMEN+ L+T
Sbjct: 378 VSIYAVPENIGQVHYALETTVKLLEFFQNYFEIQYPLKKLDLVAIPDFEAGAMENWGLLT 437
Query: 303 FRPSALLYDGNLDEPDAAALQKIAYVVSHEIAHQWFGNLVTMKWWDELWLNEGFATWIGY 362
FR LLYD N A + + +++HE+AHQWFGNLVTMKWW++LWLNEGFAT++ Y
Sbjct: 438 FREETLLYDSNTSS--MADRKLVTKIIAHELAHQWFGNLVTMKWWNDLWLNEGFATFMEY 495
Query: 363 LAVEKFFPDWDVPSMIMLQSHEVALELDSLKESHPIKVAVRNAKDIDQVFDSISYLKGCS 422
++EK F + L + ++ DSL SHPI +V++++ I+++FDS+SY KG S
Sbjct: 496 FSLEKIFKELS-SYEDFLDARFKTMKKDSLNSSHPISSSVQSSEQIEEMFDSLSYFKGSS 554
Query: 423 ILEMVSGYLGQELFLKGVALYLKRNKFSNATMEDLFNCIGEVAD--IEVLERCKNWILTI 480
+L M+ YL +++F V LYL + +++ +DL++ EV + ++V K W L
Sbjct: 555 LLLMLKTYLSEDVFQHAVVLYLHNHSYASIQSDDLWDSFNEVTNQTLDVKRMMKTWTLQK 614
Query: 481 GYPLVTVTESEIGLSLTQNRFL--STGTCKPDEDVTKWWVPL---------MPLQGDYKV 529
G+PLVTV + L + Q RF +P + W +PL Q +
Sbjct: 615 GFPLVTVQKKGKELFIQQERFFLNMKPEIQPSDTSYLWHIPLSYVTEGRNYSKYQSVSLL 674
Query: 530 D-FSGKTTELPKTQFNHFNANSFGFYRVKY---DSDHLFQQQLQNLDKLSSRGKMGLISD 585
D SG + + N N G+Y V Y D + L Q N LS + + LI++
Sbjct: 675 DKKSGVINLTEEVLWVKVNINMNGYYIVHYADDDWEALIHQLKINPYVLSDKDRANLINN 734
Query: 586 V 586
+
Sbjct: 735 I 735
>Hs7019561 [EO] KOG1046 Puromycin-sensitive aminopeptidase and related
aminopeptidases
Length = 1024
Score = 297 bits (761), Expect = 4e-80
Identities = 196/602 (32%), Positives = 305/602 (50%), Gaps = 60/602 (9%)
Query: 17 HYEIELSELDAEHNSFIGSVRIIMSTVNANDMISLNMRDIEIVSAVVELKEGSVSLGMKD 76
HY + L+ E+ +F G V + ++ NA + L+ + + V+L E +
Sbjct: 149 HYNLMLTAF-MENFTFSGEVNVEIACRNATRYVVLHASRVAVEK--VQLAEDRAFGAVPV 205
Query: 77 HSFDL--ENDVVSLKFPESI-SDDEFVLKIDYKGMIQTNMSGFYRSDYTDFVTGENKVMF 133
F L + V+ + ++ + + LKI Y +I+ + GF+RS Y + GE + +
Sbjct: 206 AGFFLYPQTQVLVVVLNRTLDAQRNYNLKIIYNALIENELLGFFRSSYV--LHGERRFLG 263
Query: 134 STQFEATDARRAFPCFDEPSLKATFDICIIAHEKYTVLANMPLKCTKKLTESDQISYRFH 193
TQF T AR+AFPCFDEP KATF I I Y L+NMP++ T E ++ F
Sbjct: 264 VTQFSPTHARKAFPCFDEPIYKATFKISIKHQATYLSLSNMPVE-TSVFEEDGWVTDHFS 322
Query: 194 TTPLMSTYLVAWAVGEYDYIESETEKSIYPTIENYNTQDGTSSGCGKLPVKVYTAKGKAQ 253
TPLMSTY +AWA+ + Y E+ T+ + + Y D G
Sbjct: 323 QTPLMSTYYLAWAICNFTYRETTTKSGV--VVRLYARPDAIRRG---------------- 364
Query: 254 QGKFALDVAKRVIDFFSESFEIPYPLPKLDLLCVETYSHNAMENFSLITFRPSALLYDGN 313
G +AL + KR+I+F+ + F++PY LPKLDLL V + + AMEN+ L F +L D +
Sbjct: 365 SGDYALHITKRLIEFYEDYFKVPYSLPKLDLLAVPKHPYAAMENWGLSIFVEQRILLDPS 424
Query: 314 LDEPDAAALQKIAYVVSHEIAHQWFGNLVTMKWWDELWLNEGFATWIGYLAVEKFFPDWD 373
+ + L + V+ HEI HQWFG+LVT WW+++WL EGFA + ++ + +P W+
Sbjct: 425 VSS--ISYLLDVTMVIVHEICHQWFGDLVTPVWWEDVWLKEGFAHYFEFVGTDYLYPGWN 482
Query: 374 VPSMIMLQS--HEVALELDSLKESHPIKVAVRNAKDIDQVFDSISYLKGCSILEMVSGYL 431
+ L HEV L LD L SHP+ V A DID+VFD I+Y KG +++ M++ ++
Sbjct: 483 MEKQRFLTDVLHEVML-LDGLASSHPVSQEVLQATDIDRVFDWIAYKKGAALIRMLANFM 541
Query: 432 GQELFLKGVALYLKRNKFSNATMEDLFNCIGEVAD-----IEVLERCKNWILTIGYPLVT 486
G +F +G+ YL +K+ NA DL+N + E + + E W L +GYP++T
Sbjct: 542 GHSVFQRGLQDYLTIHKYGNAARNDLWNTLSEALKRNGKYVNIQEVMDQWTLQMGYPVIT 601
Query: 487 V---TESEIGLSLTQNRFL-----STGTCKPDEDVTKWWVPLMPLQGDYK-------VDF 531
+ T +E + +TQ F+ T K + W +PL + G+ +
Sbjct: 602 ILGNTTAENRIIITQQHFIYDISAKTKALKLQNNSYLWQIPLTIVVGNRSHVSSEAIIWV 661
Query: 532 SGKT-----TELPKTQFNHFNANSFGFYRVKYDSDH---LFQQQLQNLDKLSSRGKMGLI 583
S K+ T L K + N N G++RV YD + L Q ++N + LS + GLI
Sbjct: 662 SNKSEHHRITYLDKGSWLLGNINQTGYFRVNYDLRNWRLLIDQLIRNHEVLSVSNRAGLI 721
Query: 584 SD 585
D
Sbjct: 722 DD 723
>7301772 [EO] KOG1046 Puromycin-sensitive aminopeptidase and related
aminopeptidases
Length = 932
Score = 286 bits (733), Expect = 7e-77
Identities = 202/666 (30%), Positives = 310/666 (46%), Gaps = 80/666 (12%)
Query: 9 LPTDFRANHYEIELSEL--DAEHNSFIGSVRIIMSTVNANDMISLNMRDIEIVSAVVELK 66
LPT R Y + + L + E F GSV+I++ + ++L+ +++ I + + L+
Sbjct: 34 LPTSLRPQKYHLRILTLLENPEDLRFSGSVKILIEALENTKNVTLHSKNLTIDESQITLR 93
Query: 67 ----EGSVSLGMKDHSFDLENDVVSLKF-PESISDDEFVLKIDYKGMIQTNMSGFYRSDY 121
EG + + + +D L E ++ + + L + + + + G+YRS Y
Sbjct: 94 QIGGEGKKENCVSSTAVNPSHDFYILNTCQELLAGNTYELYMPFAADLNRQLEGYYRSSY 153
Query: 122 TDFVTGENKVMFSTQFEATDARRAFPCFDEPSLKATFDICIIAHEKYTVLANMPLKCTKK 181
D V K + TQFE AR AFPCFDEP KA F + + H+KYT ++NMP K TK
Sbjct: 154 KDPVANLTKWISVTQFEPASARLAFPCFDEPDFKAPFVVTLGYHKKYTAISNMPEKETKP 213
Query: 182 L-TESDQISYRFHTTPLMSTYLVAWAVGEYDYIESETEKSIYPTIENYNTQDGTSSGCGK 240
T +D I F + MSTYLVA++V ++ + S S
Sbjct: 214 HETLADYIWCEFQESVPMSTYLVAYSVNDFSHKPSTLPNSAL------------------ 255
Query: 241 LPVKVYTAKGKAQQGKFALDVAKRVIDFFSESFEIPYPLPKLDLLCVETYSHNAMENFSL 300
+ + Q +A +V+ ++ + F I +PLPK+D + V +S AMEN+ L
Sbjct: 256 --FRTWARPNAIDQCDYAAQFGPKVLQYYEQFFGIKFPLPKIDQIAVPDFSAGAMENWGL 313
Query: 301 ITFRPSALLYDGNLDEPDAAALQKIAYVVSHEIAHQWFGNLVTMKWWDELWLNEGFATWI 360
+T+R ALLY A Q++A VV+HE+AHQWFGNLVTMKWW +LWLNEGFAT++
Sbjct: 314 VTYREIALLYSAA--HSSLADKQRVASVVAHELAHQWFGNLVTMKWWTDLWLNEGFATYV 371
Query: 361 GYLAVEKFFPDWDVPSMIMLQSHEVALELDSLKESHPIKVAVRNAKDIDQVFDSISYLKG 420
L VE P+W L + D+L+ SHPI ++ +I + FD ISY KG
Sbjct: 372 ASLGVENINPEWRSMEQESLSNLLTIFRRDALESSHPISRPIQMVSEISESFDQISYQKG 431
Query: 421 CSILEMVSGYLGQELFLKGVALYLKRNKFSNATMEDLFNCIGEVA--------DIEVLER 472
++L M+ +LG+E F G+ YL++ + NA ++L+ + + A ++
Sbjct: 432 STVLRMMHLFLGEESFRSGLQAYLQKFSYKNAEQDNLWESLTQAAHKYRSLPKSYDIKSI 491
Query: 473 CKNWILTIGYPLVTVTESEIG--LSLTQNRFLSTGTCKPDEDVTKWWVPLMPLQGDYKVD 530
+W L GYP++ VT L Q R+L WWVPL + D
Sbjct: 492 MDSWTLQTGYPVINVTRDYAARTAKLNQERYLLNTQVARAYRGGCWWVPLSYTTQAVQ-D 550
Query: 531 FS----------GKTTE-LPKT--------QFNHFNANSFGFYRVKYDSDHLFQQQLQNL 571
F+ GK E LPKT Q+ FN Y+V YD+ Q + L
Sbjct: 551 FNNTAPKAWMECGKNGESLPKTIQDLPGPDQWVIFNTQLSTLYKVNYDA-----QNWKLL 605
Query: 572 DKLSSRGKMGLISDVEVTECVKNLLTLISKFTNHQD-------------PNDYYVWSIIF 618
+ + G I + + + + L L +T QD +Y W F
Sbjct: 606 IETLTNGDFERIHVINRAQLIDDALYL--AWTGEQDYEIAMRLIEYLQREREYLPWKSAF 663
Query: 619 DTLNRM 624
+ L R+
Sbjct: 664 ENLKRV 669
>Hs20149637 [EO] KOG1046 Puromycin-sensitive aminopeptidase and related
aminopeptidases
Length = 948
Score = 284 bits (727), Expect = 4e-76
Identities = 231/910 (25%), Positives = 395/910 (43%), Gaps = 87/910 (9%)
Query: 17 HYEIELSELDAEHNSFIGSVRIIMSTVNANDMISLNMRDIEIVSAVVELKEGSVSLGMKD 76
HY++ L + +F G+ ++ ++ I L+ ++I A L++G+ ++
Sbjct: 62 HYDL-LIHANLTTLTFWGTTKVEITASQPTSTIILHSHHLQISRAT--LRKGAGERLSEE 118
Query: 77 HSFDLEN---DVVSLKFPESISDD-EFVLKIDYKGMIQTNMSGFYRSDYTDFVTGENKVM 132
LE+ + ++L PE + + + I Y G + GFY+S Y GE +++
Sbjct: 119 PLQVLEHPPQEQIALLAPEPLLVGLPYTVVIHYAGNLSETFHGFYKSTYRT-KEGELRIL 177
Query: 133 FSTQFEATDARRAFPCFDEPSLKATFDICIIAHEKYTVLANMPLKCTKKLTESDQISYRF 192
STQFE T AR AFPCFDEP+ KA+F I I ++ ++NMPL + + E I F
Sbjct: 178 ASTQFEPTAARMAFPCFDEPAFKASFSIKIRREPRHLAISNMPLVKSVTVAEG-LIEDHF 236
Query: 193 HTTPLMSTYLVAWAVGEYDYIESETEKSIYPTIENYNTQDGTSSGCGKLPVKVYTAKGKA 252
T MSTYLVA+ + +++ + T+ + V VY K
Sbjct: 237 DVTVKMSTYLVAFIISDFESVSKITKSGV--------------------KVSVYAVPDKI 276
Query: 253 QQGKFALDVAKRVIDFFSESFEIPYPLPKLDLLCVETYSHNAMENFSLITFRPSALLYDG 312
Q +ALD A +++F+ + F IPYPLPK DL + + AMEN+ L T+R SALL+D
Sbjct: 277 NQADYALDAAVTLLEFYEDYFSIPYPLPKQDLAAIPDFQSGAMENWGLTTYRESALLFDA 336
Query: 313 NLDEPDAAALQKIAYVVSHEIAHQWFGNLVTMKWWDELWLNEGFATWIGYLAVEKFFPDW 372
++ A++ I V+HE+AHQWFGNLVTM+WW++LWLNEGFA ++ +++V P+
Sbjct: 337 --EKSSASSKLGITVTVAHELAHQWFGNLVTMEWWNDLWLNEGFAKFMEFVSVSVTHPEL 394
Query: 373 DVPSMIMLQSHEVALELDSLKESHPIKVAVRNAKDIDQVFDSISYLKGCSILEMVSGYLG 432
V + + A+E+D+L SHP+ V N I ++FD +SY KG IL M+ YL
Sbjct: 395 KVGDYFFGKCFD-AMEVDALNSSHPVSTPVENPAQIREMFDDVSYDKGACILNMLREYLS 453
Query: 433 QELFLKGVALYLKRNKFSNATMEDLFNCIGEVA--------------------------- 465
+ F G+ YL+++ + N EDL++ + +
Sbjct: 454 ADAFKSGIVQYLQKHSYKNTKNEDLWDSMASICPTDGVKGMDGFCSRSQHSSSSSHWHQE 513
Query: 466 DIEVLERCKNWILTIGYPLVTVTESEIGLSLTQNRFLSTGTCKPDEDVTKWWVPLMPLQG 525
++V W L G+PL+T+T + + Q ++ PD W VPL +
Sbjct: 514 GVDVKTMMNTWTLQRGFPLITITVRGRNVHMKQEHYMKGSDGAPDTGYL-WHVPLTFITS 572
Query: 526 D----YKVDFSGKTTEL---PKTQFNHFNANSFGFYRVKYDSDHLFQQQLQNLDKLSS-- 576
++ KT L + ++ FN G+Y V Y+ D D L+
Sbjct: 573 KSNMVHRFLLKTKTDVLILPEEVEWIKFNVGMNGYYIVHYEDD--------GWDSLTGLL 624
Query: 577 RGKMGLISDVEVTECVKNLLTLIS----KFTNHQDPNDYYVWSI-IFDTLNRMKSLLSSD 631
+G +S + + N L+S D + Y I + L+
Sbjct: 625 KGTHTAVSSNDRASLINNAFQLVSIGKLSIEKALDLSLYLKHETEIMPVFQGLNELIPMY 684
Query: 632 KAVKKALDNFTLDLIQPSIEKLL-EFLDQQKTNSFSKNPDNFLSNQFFELMALGAGTASH 690
K ++K N + + +LL + +D+Q + L ++ L +
Sbjct: 685 KLMEKRDMNEVETQFKAFLIRLLRDLIDKQTWTDEGSVSEQMLRSELLLLACVHNYQPCV 744
Query: 691 PETVAKCREMFESKSYSPVFRNVLLQIILSQPDXXXXXXXXXXXXXXXSTLVYKESLLTA 750
R+ ES + +V L + + K + A
Sbjct: 745 QRAEGYFRKWKESNGNLSLPVDVTLAVFAVGAQSTEGWDFLYSKYQFSLSSTEKSQIEFA 804
Query: 751 LGKIKNAELFDTVLNLLL---IIEPMDVQFLATSLGSNYAIRTKLWNFIKTNYVKLHERL 807
L + +N E +L+ I+ + + T +G N W F++ N+ KL ++
Sbjct: 805 LCRTQNKEKLQWLLDESFKGDKIKTQEFPQILTLIGRNPVGYPLAWQFLRKNWNKLVQKF 864
Query: 808 AINTVVIDRFLRFSMKDLMGEDVKTDYELFFADKNMEGFD-RGVRQTLERIEKNTRYFET 866
+ + I + + + + FF+ G R V+QT+E IE+N + +
Sbjct: 865 ELGSSSIAHMVMGTTNQFSTRTRLEEVKGFFSSLKENGSQLRCVQQTIETIEENIGWMDK 924
Query: 867 NLSLVKEYFK 876
N ++ + +
Sbjct: 925 NFDKIRVWLQ 934
>7299744 [EO] KOG1046 Puromycin-sensitive aminopeptidase and related
aminopeptidases
Length = 988
Score = 283 bits (725), Expect = 6e-76
Identities = 242/900 (26%), Positives = 402/900 (43%), Gaps = 86/900 (9%)
Query: 9 LPTDFRANHYEIELSELDAEHNSFIGSVRIIMSTVNANDMISLNMRDIEIVSAVVELKEG 68
LP + HY++ L + E F G I ++ A D I L+ ++ I S+V + G
Sbjct: 123 LPGTLKPTHYDLYLFP-NIETGEFSGQETITITVEEATDQIVLHSLNLNI-SSVSIMNTG 180
Query: 69 SVSLGMKDHSFDLENDVVSLKFPESISDDEFV-LKIDYKGMIQTNMSGFYRSDYTDFVTG 127
S +L + + + D + + + E ++ V L I ++G + + G Y S Y
Sbjct: 181 SDTLEILETTVDAVREFLIFQLNEPLTKGRTVRLHIGFEGSMANKIVGLYSSSYVK-EDE 239
Query: 128 ENKVMFSTQFEATDARRAFPCFDEPSLKATFDICII--AHEKYTVLANMPLKCTKKLTES 185
K + +++FE T AR+AFPCFDEP+LKA F I ++ + E Y L+NM + +
Sbjct: 240 TRKWIATSKFEPTYARQAFPCFDEPALKAEFTITLVHPSGEDYHALSNMNVDSSVSQGAF 299
Query: 186 DQISYRFHTTPLMSTYLVAWAVGEYDYIESETEKSIYPTIENYNTQDGTSSGCGK-LPVK 244
+++ F + MSTYL + V ++ Y + + + G G+ +
Sbjct: 300 QEVT--FAKSVPMSTYLACFIVSDFAYKQVSID----------------TKGIGETFSMS 341
Query: 245 VYTAKGKAQQGKFALDVAKRVIDFFSESFEIPYPLPKLDLLCVETYSHNAMENFSLITFR 304
VY + + A+ + K VI+++ + F+I YPLPKLD+ + + AME++ L+T+R
Sbjct: 342 VYATPEQLDKVDLAVTIGKGVIEYYIDYFQIAYPLPKLDMAAIPDFVSGAMEHWGLVTYR 401
Query: 305 PSALLYDGNLDEPDAAALQKIAYVVSHEIAHQWFGNLVTMKWWDELWLNEGFATWIGYLA 364
++LLYD A Q+IA V++HE AH WFGNLVTM WW++LWLNEGFA+++ YL
Sbjct: 402 ETSLLYDEATSS--ATNKQRIASVIAHEFAHMWFGNLVTMNWWNDLWLNEGFASFVEYLG 459
Query: 365 VEKFFPDWDVPSMIMLQSHEVALELDSLKESHPIKVAVRNAKDIDQVFDSISYLKGCSIL 424
V+ +P+W + S L LD SHPI V N I ++FD+I+Y KG S++
Sbjct: 460 VDAVYPEW------KMASAPSVLTLDGTLGSHPIIQTVENPDQITEIFDTITYSKGSSLV 513
Query: 425 EMVSGYLGQELFLKGVALYLKRNKFSNATMEDLFNCIGEV-ADIEVLERCKNWILTIGYP 483
M+ +LG+ F + V YL K+S A + F I ++ V E W + +G P
Sbjct: 514 RMLEDFLGETTFRQAVTNYLNEYKYSTAETGNFFTEIDKLELGYNVTEIMLTWTVQMGLP 573
Query: 484 LVTVTE-SEIGLSLTQNRFLST-----GTCKPDEDVTKWWVPLMPLQGDYKV-------- 529
+VT+ + S+ LTQ RFLS +P E +W +P+ V
Sbjct: 574 VVTIEKVSDTEYKLTQKRFLSNPNDYDADHEPSEFNYRWSIPITYFTSSDSVVQRLWFYH 633
Query: 530 DFSGKTTELP-KTQFNHFNANSFGFYRVKYDSD---HLFQQQLQNLDKLSSRGKMGLISD 585
D S T +P ++ FNA+ G+YRV YD+D L Q + S + L++D
Sbjct: 634 DQSEITVTVPAAVEWIKFNADQVGYYRVNYDTDLWNDLADQLVVQPSAFGSVDRAHLLND 693
Query: 586 V-EVTECVKNLLTLISKFTNHQD-PNDYYVWSIIFDTLNRMKSLLSSDKAVKKALDNFTL 643
+ + + + T + D DY WS+ L +K L K +
Sbjct: 694 AFALADSTQLPYATAFELTRYLDKETDYVPWSVAASRLTSLKRTLYYTSTYAK-YKKYAT 752
Query: 644 DLIQPSIEKLLEFLDQQKTNSFSKNPDNFLSNQFFELMALGAGTASHPET-VAKCREMF- 701
LI+P L + ++ L N+ + AL A + E+ + + E F
Sbjct: 753 ALIEPIYTALTWTVG-----------EDHLDNR-LRVTALSAACSLGLESCLTEAGEQFN 800
Query: 702 ------ESKSYSPVFRNVL---LQIILSQPDXXXXXXXXXXXXXXXSTLVYKESLLTALG 752
E + + V V +Q + SQ D K L+ L
Sbjct: 801 AWLAKPEDRPKADVRETVYYYGIQSVGSQEDWDAVWELFVNESDASE----KSKLMYGLS 856
Query: 753 KIKNAELFDTVLNLLL---IIEPMDVQFLATSLGSNYAIRTKLWNFIKTNYVKLHERLAI 809
I+ + ++L + D T + +N + +W++++ N+ +L +R +
Sbjct: 857 AIQIPWILQRYIDLAWNEEYVRGQDYFTCLTYISANPVGESLVWDYVRENWQRLVDRFGL 916
Query: 810 NTVVIDRFLRFSMKDLMGEDVKTDYELFFADKNMEGFDRGVR-QTLERIEKNTRYFETNL 868
N + + + + E FFA G R + LE ++ N + NL
Sbjct: 917 NERYLGNLIPSITARFSTQTKLEEMEQFFAKYPEAGAGTAARVRALETVKNNIVWLAENL 976
>7301771 [EO] KOG1046 Puromycin-sensitive aminopeptidase and related
aminopeptidases
Length = 1082
Score = 278 bits (711), Expect = 3e-74
Identities = 170/532 (31%), Positives = 279/532 (51%), Gaps = 44/532 (8%)
Query: 9 LPTDFRANHYEIELSEL--DAEHNSFIGSVRIIMSTVNANDMISLNMRDIEIVSAVVELK 66
LPT R Y + + L + F G+V+I++ + I+L+ +++ I + + L+
Sbjct: 29 LPTALRPQRYYLRILTLLESPDDLRFAGNVQIVIKALQNTRNITLHSKNLTIDESRITLR 88
Query: 67 E----GSVSLGMKDHSFDLENDV-VSLKFPESISDDEFVLKIDYKGMIQTNMSGFYRSDY 121
+ G++ + S + +D + E ++ + + L + + + + G+YRS Y
Sbjct: 89 QISGAGNMDNCVSSTSVNPTHDYYIFHTCKELLAGNVYKLFLPFSADLTPQLFGYYRSSY 148
Query: 122 TDFVTGENKVMFSTQFEATDARRAFPCFDEPSLKATFDICIIAHEKYTVLANMPLKCTKK 181
D VT + + + +TQFE + AR+AFPCFDEP KA+F + + H+++ L+NMP++ +
Sbjct: 149 KDPVTNKTRWLSATQFEPSSARKAFPCFDEPGFKASFVVTLGYHKQFNALSNMPVREIRP 208
Query: 182 LTE-SDQISYRFHTTPLMSTYLVAWAVGEYDYIESETEKSIYPTIENYNTQDGTSSGCGK 240
++ I F + MSTYLVA++V ++ + S T+ N G
Sbjct: 209 HESLANYIWCEFQESVPMSTYLVAYSVNDFSFKPS--------TLPN-----------GA 249
Query: 241 LPVKVYTAKGKAQQGKFALDVAKRVIDFFSESFEIPYPLPKLDLLCVETYSHNAMENFSL 300
L + + Q +A + +V+ ++ E F I YPLPK+D + V +S AMEN+ L
Sbjct: 250 L-FRTWARPNAIDQCDYAAEFGPKVLQYYEEFFGIRYPLPKIDQMAVPDFSAGAMENWGL 308
Query: 301 ITFRPSALLYDGNLDEPDAAALQKIAYVVSHEIAHQWFGNLVTMKWWDELWLNEGFATWI 360
+ +R S LLY A Q +A V++HE+AHQWFGNLVTMKWW +LWLNEGFAT++
Sbjct: 309 VKYRESTLLYSPT--HSSLADKQDLANVIAHELAHQWFGNLVTMKWWTDLWLNEGFATYV 366
Query: 361 GYLAVEKFFPDWDVPSMIMLQSHEVALELDSLKESHPIKVAVRNAKDIDQVFDSISYLKG 420
L V++ +P+W L + A LDSL SHPI ++ +I++ FD+ISY KG
Sbjct: 367 AGLGVQEIYPEWHSRDKGSLTALMTAFRLDSLVSSHPISRPIQMVTEIEESFDAISYQKG 426
Query: 421 CSILEMVSGYLGQELFLKGVALYLKRNKFSNATMEDLFNCIGEVA----------DIEVL 470
++L M+ ++G+E F G+ YLK + NA +L+ + A DI +
Sbjct: 427 SAVLRMMHLFMGEESFRTGLREYLKLYAYKNAEQNNLWESLTTAAHQNGALPGHYDINTI 486
Query: 471 ERCKNWILTIGYPLVTVTE--SEIGLSLTQNRFLSTGTCKPDEDVTKWWVPL 520
+W L G+P++ +T S +TQ R+L + V WWVPL
Sbjct: 487 --MDSWTLQTGFPVLNITRDYSTGTAEITQERYLRNSQIPQADRVGCWWVPL 536
>7299745 [EO] KOG1046 Puromycin-sensitive aminopeptidase and related
aminopeptidases
Length = 913
Score = 278 bits (710), Expect = 3e-74
Identities = 190/590 (32%), Positives = 300/590 (50%), Gaps = 53/590 (8%)
Query: 9 LPTDFRANHYEIELSELDAEHNSFIGSVRIIMSTVNANDMISLNMRDIEIVSAVVELKEG 68
LPT+ HYE+ D E +F G RI + V A + I L+ ++I S V
Sbjct: 68 LPTNLVPTHYELYWHP-DLETGNFTGQQRISIKVVEATNQIILHSYLLDITSVYV----- 121
Query: 69 SVSLGMKDHSFDLEND----VVSLKFPESISDDEFVLKIDYKGMIQTNMSGFYRSDYTDF 124
L + F+LE + +++L E D L I + G ++ + G Y S Y +
Sbjct: 122 ---LNREVEKFELEEERQFLIITLT-EELAVDASITLGIIFGGQMKDKLVGLYSSTYLN- 176
Query: 125 VTGENKVMFSTQFEATDARRAFPCFDEPSLKATFDICIIAHE-KYTVLANMPLKCTKKLT 183
G + + +T+FE T AR+AFPCFDEP++KATF I ++ Y ++NM + T+
Sbjct: 177 EAGATRTISTTKFEPTYARQAFPCFDEPAMKATFAITVVHPSGSYHAVSNM--QQTESNY 234
Query: 184 ESDQISYRFHTTPLMSTYLVAWAVGEYDYIESETEKSIYPTIENYNTQDGTSSGCGK-LP 242
D F T+ MSTYLV V ++ +S T K+ +G G+
Sbjct: 235 LGDYTEAIFETSVSMSTYLVCIIVSDFAS-QSTTVKA---------------NGIGEDFS 278
Query: 243 VKVYTAKGKAQQGKFALDVAKRVIDFFSESFEIPYPLPKLDLLCVETYSHNAMENFSLIT 302
++ Y + + +FAL+ + V +++ + +++PYPL KLD+ + ++ AME++ L+T
Sbjct: 279 MQAYATSHQINKVEFALEFGQAVTEYYIQYYKVPYPLTKLDMAAIPDFASGAMEHWGLVT 338
Query: 303 FRPSALLYDGNLDEPDAAALQKIAYVVSHEIAHQWFGNLVTMKWWDELWLNEGFATWIGY 362
+R +ALLYD + A Q IA ++HEIAHQWFGNLVTMKWW++LWLNEGFA ++ Y
Sbjct: 339 YRETALLYDPSYSS--TANKQSIAGTLAHEIAHQWFGNLVTMKWWNDLWLNEGFARYMQY 396
Query: 363 LAVEKFFPDWDVPSMIMLQSHEVALELDSLKESHPIKVAVRNAKDIDQVFDSISYLKGCS 422
V PDW + + + + L D+ SHPI V + +I +FD+ISY KG S
Sbjct: 397 KGVNAVHPDWGMLEQFQIVALQPVLLYDAKLSSHPIVQKVESPDEITAIFDTISYEKGGS 456
Query: 423 ILEMVSGYLGQELFLKGVALYLKRNKFSNATMEDLFNCI-GEVADIEVLERCKNWILTIG 481
++ M+ +G E F + V YL +++F+N +D + V D+++ + W +G
Sbjct: 457 VIRMLETLVGAEKFEEAVTNYLVKHQFNNTVTDDFLTEVEAVVTDLDIKKLMLTWTEQMG 516
Query: 482 YPLVTVTESEIG-LSLTQNRFLSTGTC---KPDEDV--TKWWVPLMPLQGD-------YK 528
YP++ V++ G +TQ RFLS P + KW VP+ D Y
Sbjct: 517 YPVLNVSKVADGSFKVTQQRFLSNPASYEEAPSDSAYGYKWSVPITWFADDGSENSFIYD 576
Query: 529 VDFSGKTTELP-KTQFNHFNANSFGFYRVKYDSDHLFQQQLQNLDKLSSR 577
D +P + Q+ N N G+YRV Y+ + L+ +Q L +R
Sbjct: 577 YDVDSVGIAVPSEVQWIKLNVNQTGYYRVNYE-ESLWALLIQQLTTSPAR 625
>7300768 [EO] KOG1046 Puromycin-sensitive aminopeptidase and related
aminopeptidases
Length = 1878
Score = 266 bits (680), Expect = 1e-70
Identities = 202/667 (30%), Positives = 318/667 (47%), Gaps = 73/667 (10%)
Query: 1 MADVKIQTLPTDFRANHYEIELS-ELDAEHNSFIGSVRIIMSTVNANDMISLNMRDIEIV 59
+AD LP D +HY + LS + F G+V I +S +N I ++ R +E
Sbjct: 976 LADEDNYRLPYDTIPSHYAVSLSTNVHTGDTVFNGTVAITLSVLNTTTKIVVHARQLENF 1035
Query: 60 SAVVELKEGSVSLGMKD--HSFDLENDVVS-----LKFPESISDDEFVLKIDYKGMIQTN 112
+A + +++G ++ + ++ E + ++ L FPE D ++L I+Y+G ++T+
Sbjct: 1036 TASI-IQQGVTEAVAQELVYEYEAEREFLTFSKTGLTFPE---DTTWILTINYQGHLRTD 1091
Query: 113 MSGFYRSDYTDFVTGENKVMFSTQFEATDARRAFPCFDEPSLKATFDICIIAHEKYTVLA 172
GFY S YTD G K + +TQFE+TDAR AFPC+DEPS +A F I I Y ++
Sbjct: 1092 NGGFYLSTYTD-EEGNTKYLATTQFESTDARHAFPCYDEPSKRAEFTITIKHDPSYNAIS 1150
Query: 173 NMPLKCTKKLTESDQISYRFHTTPLMSTYLVAWAVGEYDYIESETEKSIYPTIENYNTQD 232
NMP+ + T + F T M +YLVA+ V E+ + E E
Sbjct: 1151 NMPVDSSS--TSGVTV---FQKTVNMPSYLVAFIVSEFVFSEGELNG------------- 1192
Query: 233 GTSSGCGKLPVKVYTAKGKAQQGKFALDVAKRVIDFFSESFEIPYPLPKLDLLCVETYSH 292
LP +V++ G + ++AL V S F++P+ LPKLD + ++
Sbjct: 1193 --------LPQRVFSRNGTEHEQEWALTTGMLVEKRLSGYFDVPFALPKLDQAGIPDFAA 1244
Query: 293 NAMENFSLITFRPSALLYDGNLDEPDAAALQKIAYVVSHEIAHQWFGNLVTMKWWDELWL 352
AMEN+ L T+R LLY N + + IA + +HE AH WFG+LV ++WW LWL
Sbjct: 1245 GAMENWGLATYREEYLLY--NTENSTTSTQTNIATIEAHEDAHMWFGDLVAIEWWSFLWL 1302
Query: 353 NEGFATWIGYLAVEKFFPDWDVPSMIMLQSHEVALELDSLKESHPIKVAVRNAKDIDQVF 412
EGFAT LAV+ +P+WD+ S++ AL D+ + P+ V+ +I ++
Sbjct: 1303 KEGFATLFENLAVDLAYPEWDIFQTFHAGSYQSALVNDASANARPMSHFVQKPSEIALLY 1362
Query: 413 DSISYLKGCSILEMVSGYLGQELFLKGVALYLKRNKFSNATMEDLFNCIGEVADIE---- 468
DS+SY K S+L+M L +F +G+ YL N+F+ A LF I + A E
Sbjct: 1363 DSVSYAKAGSVLDMWRHALTNTVFQRGLHNYLVDNQFTAANPSKLFEAIAKAAVEENYEV 1422
Query: 469 ---VLERCKNWILTIGYPLVTVTESEIGLSLTQNRFLSTGTCKPDEDVTK---WWVPLMP 522
V + +W G PL+TVT + S T + + T D+D T W+VP+
Sbjct: 1423 KATVPDMMGSWTNQGGVPLLTVTRNYDNGSFTVKQSVYTN----DKDYTNDKLWYVPINY 1478
Query: 523 LQG-----------DYKVDFSGKT--TELPKTQFNHFNANSFGFYRVKYDSDH---LFQQ 566
+ Y ++ S T ++L +T + N S G+YRV YD+ + +
Sbjct: 1479 AESKNPDFRNTEATHYLLNQSEITIYSDLDQTNWLILNKKSTGYYRVLYDAQNYQLITSA 1538
Query: 567 QLQNLDKLSSRGKMGLISDVE--VTECVKNLLTLISKFTNHQDPNDYYVWSIIFDTLNRM 624
+ K+ R + LI+D+ T TL+ T + Y WS + +
Sbjct: 1539 LITRPHKIDPRNRAQLINDLYRFATSGRVPHATLLELLTYLPQEDQYSPWSATNTVITLL 1598
Query: 625 KSLLSSD 631
LS D
Sbjct: 1599 NRYLSGD 1605
Score = 238 bits (607), Expect = 3e-62
Identities = 195/683 (28%), Positives = 313/683 (45%), Gaps = 74/683 (10%)
Query: 9 LPTDFRANHYEIEL-SELDAEHNSFIGSVRIIMSTVNANDMISLNMRDIEIVSAVVELKE 67
LP Y +EL + + F G+V I + +N I+L+ R A + ++
Sbjct: 58 LPNTTEPESYNVELWTNVHNGDTEFNGTVNIDIRVLNETSNITLHYRQTSNFEATIISRD 117
Query: 68 GSVSLGMK-DHSFDLENDVVSLKFPESI----SDDEFVLKIDYKGMIQTNMSGFYRSDYT 122
+ + + +L+ + + L + ++ + + I+Y G+ +++M GFY S YT
Sbjct: 118 VATPTAIPLTVTPELQREFLVLTQTTAGEAFGANTNWTITINYTGIHRSDMGGFYISSYT 177
Query: 123 DFVTGENKVMFSTQFEATDARRAFPCFDEPSLKATFDICIIAHEKYTVLANMPLKCTKKL 182
D GE + +TQFE+T+AR AFPC+DEP+ +A F I I YT ++NMP+
Sbjct: 178 DD-DGEQHFLATTQFESTNARHAFPCYDEPARRANFTITIHHDPSYTAISNMPVNTAA-- 234
Query: 183 TESDQISYRFHTTPLMSTYLVAWAVGEYDYIESETEKSIYPTIENYNTQDGTSSGCGKLP 242
T S + F TTP MSTYLVA+ V +++ T+ +
Sbjct: 235 TSSGVTA--FQTTPKMSTYLVAFIVSDFE---------------------STTGELNGIR 271
Query: 243 VKVYTAKGKAQQGKFALDVAKRVIDFFSESFEIPYPLPKLDLLCVETYSHNAMENFSLIT 302
+V++ KGK Q ++AL V + F +P+ LPKLD + +S AMEN+ L T
Sbjct: 272 QRVFSRKGKQDQQEWALWSGLLVESSLASYFGVPFALPKLDQAGIPDFSAGAMENWGLAT 331
Query: 303 FRPSALLYDGNLDEPDAAALQKIAYVVSHEIAHQWFGNLVTMKWWDELWLNEGFATWIGY 362
+R + + N IA ++ HE AH WFG+LV++KWW LWL EGFAT Y
Sbjct: 332 YREQYMWW--NKQNSTINLKTNIANIIGHEYAHMWFGDLVSIKWWTYLWLKEGFATLFSY 389
Query: 363 LAVEKFFPDWDVPSMIMLQSHEVALELDSLKESHPIKVAVRNAKDIDQVFDSISYLKGCS 422
+ + FP WD + + + AL D+L + P+ V+ +I +++ SY K S
Sbjct: 390 ESNDIAFPLWDTYQIFHVNDYNSALLNDALASAVPMTHYVQTPSEISNRYNTFSYAKPAS 449
Query: 423 ILEMVSGYLGQELFLKGVALYLKRNKFSNATMEDLFNCIGEVAD-------IEVLERCKN 475
+L M ++F G+ YL +N++++ DLF E AD V + +
Sbjct: 450 VLYMFKNAWTDKVFRTGLNKYLTKNQYTSCDEWDLFASFQESADELGFTLPASVDDIFSS 509
Query: 476 WILTIGYPLVTVTESEIG--LSLTQNRFLSTGTCKPDEDVTKWWVPL---MPLQGDYKVD 530
W GYPL+TVT + +++TQ R+++ K D + W+VPL + DY+ D
Sbjct: 510 WSHQAGYPLLTVTRNYNAGTITITQKRYVAN---KTDTNSATWYVPLNFATANKYDYR-D 565
Query: 531 FSG------------KTTELPKTQFNHFNANSFGFYRVKYDSDH--LFQQQLQNLD-KLS 575
S E + N + G+YR YD+ + L L++ +
Sbjct: 566 TSATHYLLNVTETVISDVEASSDDWIIVNIQNSGYYRTLYDTQNYGLITAALKSQPWRFH 625
Query: 576 SRGKMGLISDVEV---TECVKN--LLTLISKFTNHQDPNDYYVWSIIFDTLNRMKSLLSS 630
R + L+ D + T+ + + LL L+ TN Q Y WS L L
Sbjct: 626 PRNRAQLLYDTYIFVSTDRLSHSILLELLGYLTNEQ---QYAPWSTANTILTVYDRYLRG 682
Query: 631 DKAVKKALDNFTLDLIQPSIEKL 653
D + D F LI P +K+
Sbjct: 683 DDSYYNFQD-FVKRLIDPIFDKI 704
>At4g33090 [EO] KOG1046 Puromycin-sensitive aminopeptidase and related
aminopeptidases
Length = 873
Score = 258 bits (658), Expect = 4e-68
Identities = 248/927 (26%), Positives = 398/927 (42%), Gaps = 149/927 (16%)
Query: 9 LPTDFRANHYEIELSELDAEHNSFIGSVRIIMSTVNANDMISLNMRDIEIVSAVVELKEG 68
LP Y++ L+ D +F G+V I + V I LN D+ + A V
Sbjct: 10 LPKFAVPKRYDLRLNP-DLIACTFTGTVAIDLDIVADTRFIVLNAADLSVNDASVSFTPP 68
Query: 69 SVSLGMKDHSFDL--ENDVVSLKFPESISDDEFVLKIDYKGMIQTNMSGFYRSDY----- 121
S S + L E++++ L+F E + VLK+ + G++ M GFYRS
Sbjct: 69 SSSKALAAPKVVLFEEDEILVLEFGEILPHGVGVLKLGFNGVLNDKMKGFYRSSRLILER 128
Query: 122 --------TDFVTGENKVMFSTQFEATDARRAFPCFDEPSLKATFDICIIAHEKYTVLAN 173
T GE K M TQFE DARR FPC+DEP+ KATF I + L+N
Sbjct: 129 SCICLGGSTYEHNGEKKNMAVTQFEPADARRCFPCWDEPACKATFKITLEVPTDLVALSN 188
Query: 174 MPLKCTKKLTESDQISYRFHTTPLMSTYLVAWAVGEYDYIESETEKSIYPTIENYNTQDG 233
MP+ K +SY+ +P+MSTYLVA VG +DY+E T T E
Sbjct: 189 MPIMEEKVNGNLKIVSYQ--ESPIMSTYLVAIVVGLFDYVEDHTSDGPSLTFETL----- 241
Query: 234 TSSGCGKLPVKVYTAKGKAQQGKFALDVAKRVIDFFSESFEIPYPLPKLDLLCVETYSHN 293
C + + + ++ + F +PYPLPK+D++ + ++
Sbjct: 242 ----CACIFLSFFNG----------CIISLHKSNHSCRYFAVPYPLPKMDMIAIPDFAAG 287
Query: 294 AMENFSLITFRPSALLYDGNLDEPDAAALQKIAYVVSHEIAHQWFGNLVTMKWWDELWLN 353
AMEN+ L+T+R +ALLYD E +AA K
Sbjct: 288 AMENYGLVTYRETALLYD----EQHSAASNKQR--------------------------- 316
Query: 354 EGFATWIGYLAVEKFFPDWDVPSMIMLQSHEVALELDSLKESHPIKVAVRNAKDIDQVFD 413
+ YLA + FP+W + + + +S E L LD L+ESHPI+V V +A +ID++FD
Sbjct: 317 ------VSYLATDSLFPEWKIWTQFLDESTE-GLRLDGLEESHPIEVEVNHAAEIDEIFD 369
Query: 414 SISYLKGCSILEMVSGYLGQELFLKGVALYLKRNKFSNATMEDLFNCIGEVADIEVLERC 473
+ISY KG S++ M+ YLG E+F K +A Y+K + +SNA EDL+ + + V +
Sbjct: 370 AISYRKGASVIRMLQSYLGAEVFQKSLAAYIKNHAYSNAKTEDLWAALEAGSGEPVNKLM 429
Query: 474 KNWILTIGYPLVTVTESEIGLSLTQNRFLSTGTCKPDEDVTKWWVPLMPLQGDYK----- 528
+W GYP+V+ + L L Q+RFLS+G+ P E +W VP+ G Y+
Sbjct: 430 SSWTKQKGYPVVSAKIKDGKLELEQSRFLSSGS--PGEG--QWIVPVTLCCGSYEKRKNF 485
Query: 529 -------------------VDFSGKTTELPKTQFNHFNANSFGFYRVKYDSDHLFQQQLQ 569
D S K + N + GFYRVKYD L+
Sbjct: 486 LLESKSGAYDLKELLGCSIADGSDKIN--GTCSWIKINVDQAGFYRVKYDDS--LAAGLR 541
Query: 570 NL---DKLSSRGKMGLISD-----VEVTECVKNLLTLISKFTNHQDPNDYYVWS-IIFDT 620
N L+S + G++ D + + + +LLTL S + DY V S +I +
Sbjct: 542 NATESQSLTSIDRYGILDDSFALTMARQQSLASLLTLCSAYKKEL---DYTVLSNLIAIS 598
Query: 621 LNRMKSLLSSDKAVKKALDNFTLDLIQPSIEKLLEFLDQQKTNSFSKNPDNFLSNQFFEL 680
+K +++ + + +F + + Q + KL D ++ S + D L +
Sbjct: 599 YKVVKIGADANQELMSGIKHFFIGVFQFAAGKL--GWDPKQGES---HLDAMLRGEVLTA 653
Query: 681 MALGAGTASHPETVAKCREMFE-------SKSYSPVFRNVLLQIILSQPDXXXXXXXXXX 733
+A+ H ET+ + F+ + P R ++ + +
Sbjct: 654 LAV----FGHDETLKEAVRRFDAFLADRNTPLLPPDIRRAAYVAVMQRANKSDKSGYESL 709
Query: 734 XXXXXSTLVYKES--LLTALGKIKNAELFDTVLNLLLI--IEPMDVQFLATSLGSN---- 785
T + +E +L +L + + VLN +L ++ MD F + L N
Sbjct: 710 LRVYRETDLSQEKTRILGSLASCPDPTIVQDVLNFVLSDEVDYMDFAFHSVELVRNQDAL 769
Query: 786 YAIRTKLWNFIKTNYVKLHERLAI--NT----VVIDRFLRFSMKDLMGEDVKTDYELFFA 839
Y + W + + L E+ NT +I RF+ + + + E FFA
Sbjct: 770 YGLSGVSWEGREVAWKWLQEKWEYIGNTWGSGFLITRFISAVVSPFASFEKAKEVEEFFA 829
Query: 840 DKNMEGFDRGVRQTLERIEKNTRYFET 866
++ R ++Q++ER+ N + E+
Sbjct: 830 TRSKPSMARTLKQSIERVHINANWVES 856
>CE21162 [EO] KOG1046 Puromycin-sensitive aminopeptidase and related
aminopeptidases
Length = 988
Score = 256 bits (655), Expect = 8e-68
Identities = 173/592 (29%), Positives = 300/592 (50%), Gaps = 58/592 (9%)
Query: 26 DAEHNSFIGSVRIIMSTVNANDMISLNMRDIEIVSAVVELKEGSVSLGMKDHSFDLEN-- 83
D + +F G V I ++ + +SLN +D+ + K+ S+ + K +F L++
Sbjct: 111 DKNNLTFEGQVLIELNITKSIKKVSLNSKDLNYTEEFI--KKSSILVNGKSIAFTLDDKQ 168
Query: 84 ---DVVSLKFPESISDD-EFVLKIDYKGMIQTNMSGFYRSDYTDFVTGENKVMFSTQFEA 139
+ + E++ LK+ + ++T+MSG Y++ YT+ GE+K+ TQ E
Sbjct: 169 STHEKIFFNLDETVEPTTSATLKVAFGAPLRTDMSGLYQTTYTNS-KGESKMAAVTQMEP 227
Query: 140 TDARRAFPCFDEPSLKATFDICIIAHEKYTVLANMPLKCTKKLTESDQISYRFHTTPLMS 199
ARR PCFDEP+ KAT+ + +I H TV + ++ + + I F TP MS
Sbjct: 228 VYARRMVPCFDEPAYKATWTVTVI-HPNKTVAVSNGIEDKVEDGQPGFIISTFKPTPRMS 286
Query: 200 TYLVAWAVGEYDYIESETEKSIYPTIENYNTQDGTSSGCGKLPVKVYTAKGKAQQGKFAL 259
+YL+A + E++Y E+ T+ + +V++ + +A+
Sbjct: 287 SYLLAIFISEFEYNEATTKSGVR--------------------FRVWSRPEEKNSTMYAV 326
Query: 260 DVAKRVIDFFSESFEIPYPLPKLDLLCVETYSHNAMENFSLITFRPSALLYDGNLDEPDA 319
+ + ++++ + + I +PLPK D++ + +S AMEN+ LIT+R SALLYD +
Sbjct: 327 EAGVKCLEYYEKYYNISFPLPKQDMVALPDFSAGAMENWGLITYRESALLYDPRIYS--G 384
Query: 320 AALQKIAYVVSHEIAHQWFGNLVTMKWWDELWLNEGFATWIGYLAVEKFFP-DWDVPSMI 378
+ +++A V++HE+AHQWFGNLVT+KWW++LWLNEGFAT + YL ++ + +
Sbjct: 385 SQKRRVAVVIAHELAHQWFGNLVTLKWWNDLWLNEGFATLVEYLGTDEISDGNMRMREWF 444
Query: 379 MLQSHEVALELDSLKESHPIKVAVRNAKDIDQVFDSISYLKGCSILEMVSGYLGQELFLK 438
+ + AL DS+ +HP+ + A ++ FDS++Y KG ++L MV +G+E F
Sbjct: 445 TMDALWSALAADSVASTHPLTFKIDKAMEVLDSFDSVTYDKGGAVLAMVRKTIGEENFNT 504
Query: 439 GVALYLKRNKFSNATMEDLFNCIGEV----------ADIEVLERCKNWILTIGYPLVTVT 488
G+ YL R++F NA +L +GE + + E W +GYPL+ +
Sbjct: 505 GINHYLTRHQFDNADAGNLLTALGEKIPDSVMGPKGVKLNISEFMDPWTKQLGYPLLNAS 564
Query: 489 E-SEIGLSLTQNRFLSTGTCKPDEDVT------KWWVPL-MPLQGDYKVDFSGKTTELP- 539
+ + + Q+RF T K +E + KW VP+ + G +++ P
Sbjct: 565 RINNTHIIVEQSRFKLLATGKEEEKYSNPVWGFKWDVPVWYQVVGSSELEMKWMKRNEPL 624
Query: 540 --KTQFN-HFNANSFGFYRVKYDS---DHLFQQQLQNLDKLSSRGKMGLISD 585
K+ N NA S GFYR Y S + + +N ++ S + ++ LI D
Sbjct: 625 IIKSDKNVIINAESNGFYRAGYSSGLWKEISEMLKENHEQFSPQTRVRLIDD 676
>7301770 [EO] KOG1046 Puromycin-sensitive aminopeptidase and related
aminopeptidases
Length = 814
Score = 249 bits (636), Expect = 1e-65
Identities = 152/445 (34%), Positives = 235/445 (52%), Gaps = 30/445 (6%)
Query: 9 LPTDFRANHYEIE-LSELDAEHN-SFIGSVRIIMSTVNANDMISLNMRDIEIVSAVVELK 66
LPT R Y++ L++L+ + F G+V+I + + I+L+ +D+ I + L
Sbjct: 27 LPTALRPQSYDVRILTQLENPDDFHFNGTVKIQIEVLQNTHNITLHSKDLTIDDTEITLS 86
Query: 67 ----EGSVSLGMKDHSFDLENDVVSLKFPESISDDEFV-LKIDYKGMIQTNMSGFYRSDY 121
E + + + + +D L + + +F L + + +Q ++G+YRS Y
Sbjct: 87 QIGGEETTENCITSTAVNPTHDFYILNTCKELLAGQFYELSLPFSAKLQDQLAGYYRSSY 146
Query: 122 TDFVTGENKVMFSTQFEATDARRAFPCFDEPSLKATFDICIIAHEKYTVLANMPLKCTKK 181
+ V E + + TQFE AR AFPCFDEP KA+F I + H+KYT L+NMP+ T+
Sbjct: 147 VNTVANETRWISVTQFEPAAARLAFPCFDEPGYKASFAITLGYHKKYTGLSNMPVNETRP 206
Query: 182 LTE-SDQISYRFHTTPLMSTYLVAWAVGEYDYIESETEKSIYPTIENYNTQDGTSSGCGK 240
D + F + MSTYLVA+++ ++ + S T+ N G
Sbjct: 207 HESIPDYVWTSFEESLPMSTYLVAYSLNDFSHKPS--------TLPN-----------GT 247
Query: 241 LPVKVYTAKGKAQQGKFALDVAKRVIDFFSESFEIPYPLPKLDLLCVETYSHNAMENFSL 300
L + + Q +A ++ +V+ ++ E F I +PLPK+D + V +S AMEN+ L
Sbjct: 248 L-FRTWARPNAIDQCDYAAELGPKVLKYYEELFGIKFPLPKVDQIAVPDFSAGAMENWGL 306
Query: 301 ITFRPSALLYDGNLDEPDAAALQKIAYVVSHEIAHQWFGNLVTMKWWDELWLNEGFATWI 360
+TF S LLY +A Q+ A +V+HE+AHQWFGNLVTMKWW +LWLNEGFAT++
Sbjct: 307 VTFAESTLLYSPEYSSQEAK--QETANIVAHELAHQWFGNLVTMKWWTDLWLNEGFATYV 364
Query: 361 GYLAVEKFFPDWDVPSMIMLQSHEVALELDSLKESHPIKVAVRNAKDIDQVFDSISYLKG 420
L VE P W + + + DSL+ SHPI + I + FD ISY KG
Sbjct: 365 ASLCVEDIHPQWRTLQLESMSNLLTIFRKDSLESSHPISRPIEMTSQISESFDEISYQKG 424
Query: 421 CSILEMVSGYLGQELFLKGVALYLK 445
S++ M+ +LG+E F G+ L L+
Sbjct: 425 SSVIRMMHLFLGEEAFRTGLKLVLE 449
>CE24087 [EO] KOG1046 Puromycin-sensitive aminopeptidase and related
aminopeptidases
Length = 781
Score = 248 bits (633), Expect = 3e-65
Identities = 211/765 (27%), Positives = 352/765 (45%), Gaps = 68/765 (8%)
Query: 134 STQFEATDARRAFPCFDEPSLKATFDICIIAHEKYTVLANMPLKCTKKLTESDQISYRFH 193
+TQFE T AR+ PCFDEP+ KATF + II + + +NM + +K+ ++ I F
Sbjct: 20 ATQFEPTFARKMLPCFDEPNFKATFQVAIIRNPHHIARSNMNILISKEY-KNGLIKDVFE 78
Query: 194 TTPLMSTYLVAWAVGE-YDYIESETEKSIYPTIENYNTQDGTSSGCGKLPVKVYTAKGKA 252
+ MSTYL+A AV + Y YI+ T NTQ + V++Y +
Sbjct: 79 KSVKMSTYLLAVAVLDGYGYIKRLTR----------NTQKA-------IEVRLYAPQDML 121
Query: 253 Q-QGKFALDVAKRVIDFFSESFEIPYPLPKLDLLCVETYSHNAMENFSLITFRPSALLYD 311
Q +F LD R ++FF + F I YPL K+DLL ++ +S AMEN+ L+TFR SALL+
Sbjct: 122 TGQSEFGLDTTIRALEFFEDYFNISYPLDKIDLLALDDFSEGAMENWGLVTFRDSALLF- 180
Query: 312 GNLDEPDAAALQKIAYVVSHEIAHQWFGNLVTMKWWDELWLNEGFATWIGYLAVEKFFPD 371
N + A + IA ++ HEIAHQWFGNLVTM WW+E++LNEGFA ++ Y VE FPD
Sbjct: 181 -NERKASVVAKEHIALIICHEIAHQWFGNLVTMDWWNEVFLNEGFANYMEYKCVEHLFPD 239
Query: 372 WDVPSMIMLQSHEVALELDSLKESHPIKVAVRNAKDIDQVFDSISYLKGCSILEMVSGYL 431
W + S ++ + E D S I+ + + +FD+I+Y K +I+ M++
Sbjct: 240 WSIMSRFYAENLAFSQEPDGFLSSRAIE--SDDDDSLLNLFDAINYHKAAAIIHMIAEMA 297
Query: 432 GQELFLKGVALYLKRNKFSNATMEDLFNCIGEVADIE----VLERCKNWILTIGYPLVTV 487
GQ+ F + YL + +SNA DL+ + + A+++ + + K + +GYPL+TV
Sbjct: 298 GQKNFQNALVEYLNKYAYSNAIGVDLWKIVEKHANLQGTVSIPDLAKAYTTQVGYPLLTV 357
Query: 488 TESEIGLSL-TQNRFLSTGTCKPDE--DVTKWWVPLMPLQGDYK--------VDFSGKTT 536
++ G+ + Q RFL K +E KW +P+ +++ D T
Sbjct: 358 ERTDEGVLVHNQTRFLFAEGDKAEEKRGDWKWPIPISYRDSEHRRKKQHWIQADDKNVTW 417
Query: 537 ELPKTQFNHFNANSFGFYRVKYDSD---HLFQQQLQNLDKLSSRGK-MGLISDVEVTE-C 591
E + N G+++V YD + L +Q +N +S + M L+ ++++
Sbjct: 418 ETTSNDWLILNTGGVGYFKVLYDPETYRKLVKQLQRNHTTISPIDRSMILVDSFDLSKTS 477
Query: 592 VKNLLTLISKFTNHQDPNDYYVWSIIFDTLNRMKSLLSSDKAVKKALDNFTLDLIQPSIE 651
+ N+ + D WSI+ L +++L+ + + D + I
Sbjct: 478 LLNISVYFDLLEYVEKETDKMTWSIVGKQLRTIEALIEESDYL-----DIYQDFQRSLIM 532
Query: 652 KLLEFLDQQKTNSFSKNPD-NFLSNQFFELMALGAGTASHPETVAKCREMFESKSYSPVF 710
+L E LD + + NP+ L F + + + + S +P
Sbjct: 533 RLYESLDWDEQGA---NPNQKRLQVDIFAVACRLQIKDCTKQAYQRYLQWVSSGVRNPEH 589
Query: 711 RNVLLQIILSQPDXXXXXXXXXXXXXXXSTLVYKESLLTALGKIKNAELFDTVLNLLL-- 768
+ L + Q + S K +++ AL K+A L + +L L
Sbjct: 590 HMIALMEGVKQGETTAWERIWKAYKTATSP-SEKNNIIGALTSTKDASLINRLLKYCLDG 648
Query: 769 IIEPMDVQFLATSLGSNYAIRTKLWNFIKTNYVKLHERLAINTVVIDRFLRFSMKDLMGE 828
I+ + + + N + R +W F KT++ + H L + L S + E
Sbjct: 649 KIKANLIPRVFSYFSLNQSTRNIVWKFFKTHFEQFHGILGKGS------LMASCVKCLAE 702
Query: 829 DVKTDYEL------FFADKNMEGFDRGVRQTLERIEKNTRYFETN 867
+ T+ EL + K E + T E+IE N ++ + N
Sbjct: 703 PLSTETELEEVKEFLKSQKFAEDGLIKMEMTYEQIELNIQWRKLN 747
>7301517 [EO] KOG1046 Puromycin-sensitive aminopeptidase and related
aminopeptidases
Length = 1078
Score = 243 bits (621), Expect = 7e-64
Identities = 168/564 (29%), Positives = 269/564 (46%), Gaps = 70/564 (12%)
Query: 40 MSTVNANDMISLNMRDIEIVSA-VVELKEGSVSLGMKDHSFDLEND--------VVSLKF 90
+S V + + I L++ ++ I + V+ S ++ D ++D V++L
Sbjct: 208 VSKVTSWEPIVLDVHNVSISNVRVIRALADGASNASEEQDLDFDSDYGEDNATFVINLSK 267
Query: 91 PESISDD-EFVLKIDYKGMIQTNMSGFYRSDYTDFVTGENKVMFSTQFEATDARRAFPCF 149
++ +L +D+ + + G Y++ YT+ T + M STQF DARRAFPCF
Sbjct: 268 TLAVETQLRVLLSLDFVSQVTDTLQGIYKTSYTNPDTKNEEWMISTQFSPVDARRAFPCF 327
Query: 150 DEPSLKATFDICIIAHEKYTV-LANMPLKCTKKLTESDQISYRFHTTPLMSTYLVAWAVG 208
D P +KA F I I+ ++ + L+NMP +++ I F TTP M TYLVA+ V
Sbjct: 328 DRPDMKANFSISIVRPMQFKMALSNMPKSGSRRFRRGF-IRDDFETTPKMPTYLVAFIVS 386
Query: 209 EYDYIESETEKSIYPTIENYNTQDGTSSGCGKLP-VKVYTAKGKAQQGKFALDVAKRVID 267
+ ++S S G P V+++T +A + ++ +
Sbjct: 387 --NMVDSRL----------------ASQDSGLTPRVEIWTRPQFVGMTHYAYKMVRKFLP 428
Query: 268 FFSESFEIPYPLPKLDLLCVETYSHNAMENFSLITFRPSALLYDGNLDEPDAAA-LQKIA 326
++ + F I LPK+DL+ V + AMEN+ LITFR SALL +L ++ +Q +A
Sbjct: 429 YYEDFFGIKNKLPKIDLVSVPDFGFAAMENWGLITFRDSALLVPEDLQLASSSEHMQVVA 488
Query: 327 YVVSHEIAHQWFGNLVTMKWWDELWLNEGFATWIGYLAVEKFFPDWDVPSMIMLQSHEVA 386
+++HE+AHQWFGNLVT KWWD+LWL EGFA ++ Y A+E P++ + + + +
Sbjct: 489 GIIAHELAHQWFGNLVTPKWWDDLWLKEGFACYMSYKALEHAHPEFQSMDTLTMLEFKES 548
Query: 387 LELDSLKESHPIKVAVRNAKDIDQVFDSISYLKGCSILEMVSGYLGQELFLKGVALYLKR 446
+E D+ SH I VR+ D+ ++FD ISY KG +L M++ +G F LK+
Sbjct: 549 MEHDADNTSHAISFDVRSTNDVRRIFDPISYSKGTILLRMLNSIVGDVAFRSATRDLLKK 608
Query: 447 NKFSNATMEDLFNCIGE--------VADIEVLERCKNWILTIGYPLVTVTESEIGLSLTQ 498
+ N +DL+ + D+ V + +WI GYP+V V L L Q
Sbjct: 609 FAYGNMDRDDLWAMLTRHGHEQGTLPKDLSVKQIMDSWITQPGYPVVNVERRGADLVLRQ 668
Query: 499 NRFLSTGTCKPDEDVTKWWVPLMPLQGDYKVDFSGKTTELPK--------------TQFN 544
R+L K D + W++P+ ++ D K +P F
Sbjct: 669 ERYLLPS--KNTADQSTWFIPI-----TFETDELRKGDNIPTHWMRSEDEEELIVGNVFA 721
Query: 545 H---------FNANSFGFYRVKYD 559
H N N G+YRV YD
Sbjct: 722 HSSNSDNVIYLNLNRQGYYRVNYD 745
>7300767 [EO] KOG1046 Puromycin-sensitive aminopeptidase and related
aminopeptidases
Length = 988
Score = 232 bits (592), Expect = 2e-60
Identities = 196/763 (25%), Positives = 330/763 (42%), Gaps = 111/763 (14%)
Query: 98 EFVLKIDYKGMIQTNMSGFYRSDYTDFVTGENKVMFSTQFEATDARRAFPCFDEPSLKAT 157
++ L+I Y ++ + +G Y DY D + +TQ E T R FPC+DEP K+
Sbjct: 127 QYRLEILYTAIMASRPAGLYYMDYRDEENNHTVYVAATQCEPTYGRLIFPCYDEPGFKSN 186
Query: 158 FDICIIAHEKYTVLANMPLKCTKKLTESDQISYRFHTTPLMSTYLVAWAVGEYDYIESET 217
F I I ++ ++NMP+K + L D + FHTTP +STYLVA+ + ++ I SET
Sbjct: 187 FSIKITHGSSHSAISNMPVK--EVLAHGDLKTTSFHTTPPISTYLVAFVISDFGSI-SET 243
Query: 218 EKSIYPTIENYNTQDGTSSGCGKLPVKVYTAKGKAQQGKFALDVAKRVIDFFSESFEIPY 277
+ I +I YT+ ++G+ AL A R + + F + Y
Sbjct: 244 YRGITQSI--------------------YTSPTSKEKGQVALKNAVRTVAALEDYFGVSY 283
Query: 278 PLPKLDLLCVETYSHNAMENFSLITFRPSALLYDGNLDEPDAAALQKIAYVV-SHEIAHQ 336
PLPKLD + ++ AMEN+ LIT++ LL + + D +K+ + +HEIAHQ
Sbjct: 284 PLPKLDHVALKKNYGAAMENWGLITYKDVNLLKNISSD----GQKRKLDLITQNHEIAHQ 339
Query: 337 WFGNLVTMKWWDELWLNEGFATWIGYLAVEKFFPDWDVPSMIMLQSHEVALELDSLKESH 396
WFGNLV+ +WW W+NEGFAT+ Y+ + +P+ + M M + A +S + H
Sbjct: 340 WFGNLVSPEWWTYTWMNEGFATYFSYVITDLIYPNDKMMDMFMTHEADSAYSYNSFFDVH 399
Query: 397 PIKVAVRNAKDIDQVFDSISYLKGCSILEMVSGYLGQELFLKGVALYLKRNKFSNATMED 456
P+ V KDI VFD ISY +G +++M Q+LF++G++ +L++ ++S A +
Sbjct: 400 PMSHYVEGEKDIMGVFDIISYKRGACVIKMFHHAFRQKLFVRGISHFLEKYRYSVANELN 459
Query: 457 LFNCI-GEVADIE----------VLERCKNWILTIGYPLVTVTESEIGLSLTQNRFLSTG 505
LF+ + E+ D E + E +W + P++ VT + ++T F
Sbjct: 460 LFDALHSELQDDEYFSHQPWASRIREIMLSWTHSEWLPILVVTRNYENNTIT---FTQRS 516
Query: 506 TCKPDEDVTKWWVPL------------------MPLQGDYKVDFSGKTTELPKTQFNHFN 547
DE WW+P+ MP Q Y V + + N
Sbjct: 517 VHMKDE---LWWIPINFATTQSPNFEDTQVDMFMPPQPQYTVSLEDLNIHVSGRDWIMVN 573
Query: 548 ANSFGFYRVKYDSDHL--FQQQLQ-NLDKLSSRGKMGLISD---------VEVTECVKNL 595
GFY V+YD+D+L +QLQ N + ++GL D +E E V L
Sbjct: 574 KQHTGFYLVRYDTDNLMAIARQLQTNHSVIHPINRLGLFRDLGPLIEHNEIEQVEVVFEL 633
Query: 596 LTLISKFTNHQDPNDYYVWSIIFDTLNRMKSLLSSDKAVKKALDNFTLDLIQPSIEKLLE 655
L + + D W+ + DT+ + L + + + F L+ P+ ++
Sbjct: 634 LKYL------ELEEDVLTWNQLQDTIECLTRNLHGTSS-QSLFNEFVRRLVGPTFRRV-- 684
Query: 656 FLDQQKTNSFSKNPDNFLSNQFFELMALGAGTASHPETVAKCREMF-----------ESK 704
+ + N + F + A +A PE + R + +
Sbjct: 685 ---------YVEQGVNLAEDGMFRGILEIACSADLPECLEYTRRLAKEHIIDKIYFKDGS 735
Query: 705 SYSPVFRNVLLQIILSQPDXXXXXXXXXXXXXXXSTLVYKESLLTALGKIKNAELFDTVL 764
Y + +VL + D +++ Y + + + L +
Sbjct: 736 DYHAIIDSVLCMGVRYLSDQDFQRIIDMMQEIDRASVYYDDIIYALRCTQSHRHLLYYLE 795
Query: 765 NL-------LLIIEPMDVQFLATSLGSNYAIRTKLWNFIKTNY 800
L +++ E D+ +L SN A R +W +I+ NY
Sbjct: 796 GLMGENSTHMVLSEFEDLMYLLYIYKSNLASRPVIWQYIERNY 838
>7300769 [EO] KOG1046 Puromycin-sensitive aminopeptidase and related
aminopeptidases
Length = 1646
Score = 214 bits (544), Expect = 6e-55
Identities = 160/582 (27%), Positives = 262/582 (44%), Gaps = 61/582 (10%)
Query: 82 ENDVVSLKFPESIS-DDEFVLKIDYKGMIQTNMSGFYRSDYTDFVTGENKVMFSTQFEAT 140
+ D+V L +++ + ++L Y G+++ +M GFYRS Y D K + STQF+
Sbjct: 127 DTDIVKLTASTALTANTTYILHFVYTGLMEDDMHGFYRSSYVDD-NNVTKWLGSTQFQTH 185
Query: 141 DARRAFPCFDEPSLKATFDICIIAHEKYTVLANMPLKCTKKLTESDQISYRFHTTPLMST 200
ARRAFP FDEP KATFD+ + H + ++N L + TE S + TTP MST
Sbjct: 186 HARRAFPSFDEPQFKATFDVTLKRHRTFNSVSNTRLISSYPSTEEGIFSDVYKTTPKMST 245
Query: 201 YLVAWAVGEYDYIESETEKSIYPTIENYNTQDGTSSGCGKLPVKVYTAKGKAQQGKFALD 260
YL+A+ + E+ + + +Y E Y Q ++ +
Sbjct: 246 YLLAFIISEF-VARKDDDFGVYARPEYY------------------------AQTQYPYN 280
Query: 261 VAKRVIDFFSESFEIPY---PLPKLDLLCVETYSHNAMENFSLITFRPSALLYDGNLDEP 317
V ++++ + + Y K+D+ + +S AMEN+ L+T+R +LL D +
Sbjct: 281 VGIQILEEMGQYLDKDYYSMGNDKMDMAAIPDFSAGAMENWGLLTYRERSLLVDES--AT 338
Query: 318 DAAALQKIAYVVSHEIAHQWFGNLVTMKWWDELWLNEGFATWIGYLAVEKFFPDWDVPSM 377
A+ Q IA VV+HE AH WFG+LVT KWW WLNEGFA + Y W++
Sbjct: 339 TLASRQSIAAVVAHEQAHMWFGDLVTCKWWSYTWLNEGFARYFQYFGTAMVEDKWELEKQ 398
Query: 378 IMLQSHEVALELDSLKESHPIK-VAVRNAKDIDQVFDSISYLKGCSILEMVSGYLGQELF 436
++ + + +DS ++P+ + ++F+SISY KG + + M+ +G++ F
Sbjct: 399 FVVDQVQSVMAMDSTNATNPLSDENTYTPAHLSRMFNSISYNKGATFIRMIKHTMGEQQF 458
Query: 437 LKGVALYLKRNKFSNATMEDLF-----NCIGEVADIEVLERCKNWILTIGYPLVTVTESE 491
K + YLK+ ++ ++ E L N + + K++ +GYPL+ VT
Sbjct: 459 QKSLQEYLKKYEYQSSLPEYLLGAWQANWPNSSYNESSKDIFKSFTEQVGYPLINVTVGN 518
Query: 492 IGLSLTQNRFLSTGTCKPDEDVTKWWVPLMPLQGDYK------VDFSGKTTELPKTQFNH 545
+S TQ RFL + D + K+ VP+ + F K QFN
Sbjct: 519 SQVSFTQKRFLLKESDGSDSSL-KYTVPISYTTSETNNFLNTTPKFILKPNVTTTVQFNS 577
Query: 546 ------FNANSFGFYRVKYDSD--HLFQQQL--QNLDKLSSRGKMGLISDV----EVTEC 591
N G+YRV Y D H L N + + ++ D+
Sbjct: 578 TIKWIVVNIQQTGYYRVTYSDDNWHAIHHALITANWGGIHENNRAQIVDDLFNLARAGYV 637
Query: 592 VKNLLTLISKFTNHQDPNDYYVWSIIFDTLNRMKSLLSSDKA 633
NL + ++ Q +Y W+ F+ N + L +D A
Sbjct: 638 TYNLTLDVIEYL--QTETNYIPWTSAFNGFNYLTIRLGNDTA 677
Score = 183 bits (464), Expect = 1e-45
Identities = 114/416 (27%), Positives = 202/416 (48%), Gaps = 38/416 (9%)
Query: 99 FVLKIDYKGMIQTNMSGFYRSDYTDFVTGENKVMFSTQFEATDARRAFPCFDEPSLKATF 158
+ L Y G I+T+M+GF+ + Y + T + + TQ + +AR PCFDEP+LKA F
Sbjct: 1077 YTLGFKYTGHIRTDMAGFFSASYVERDTNVTRWLALTQMQRINARLVLPCFDEPALKAQF 1136
Query: 159 DICIIAHEKYTVLANMPLKCTKKLTESDQISYRFHTTPLMSTYLVAWAVGEYDYIESETE 218
+ I+ Y +AN LK TK L++ D+ F TP+MSTYL+A+ V Y +E+E
Sbjct: 1137 QLQIVRPNGYQSIANTKLKETKALSQ-DRFVDHFKETPVMSTYLLAFMVANYSARGNESE 1195
Query: 219 KSIYPTIENYNTQDGTSSGCGKLPVKVYTAKGKAQQGKFALDVAKRVIDFFSESFEIPYP 278
++ E Y+ + F+ V ++V+ + E F+ PY
Sbjct: 1196 FAVLTRPEFYDNTE------------------------FSYHVGQQVVSAYGELFQSPYA 1231
Query: 279 LPKLDLLCVET---YSHNAMENFSLITFRPSALLYDGNLDEPDAAALQKIAYVVSHEIAH 335
D+L + + HN MEN+ LI + L+ + + D + + +++HE +H
Sbjct: 1232 ELGNDVLQYASSPRFPHNGMENWGLIIYSDDVLIQEPGYSD-DWSDKEFAIRIIAHETSH 1290
Query: 336 QWFGNLVTMKWWDELWLNEGFATWIGYLAVEKFFPDWDVPSMIMLQSHEVALELDSLKES 395
WFG+ VT WW WLNE FA + Y + +PD+ + +++ ++ D+ +
Sbjct: 1291 MWFGDSVTFSWWSYFWLNEAFARYYEYFMAHQLYPDYHLDEQFVVRQMQLIFGTDAQNGT 1350
Query: 396 HPI---KVAVRNAKDIDQVFDSISYLKGCSILEMVSGYLGQELFLKGVALYLKRNKFSNA 452
P+ + ++ I F I+Y KG I+ M +G E F + YL++ +N
Sbjct: 1351 QPMTSPESEIQTPSQIAYKFSGIAYAKGACIVRMWRNLMGAENFDTAIRSYLQQYHLTNT 1410
Query: 453 TMEDLFNCIGE----VADIEVLERCKNWILTIGYPLVTV--TESEIGLSLTQNRFL 502
+LF + E D+++++ ++ +GYP++ V + +++ Q+RFL
Sbjct: 1411 VPYNLFYHLFEHWPKNQDVDLVDFLTDYTEQVGYPMIIVKALQGNKVVTVEQSRFL 1466
>CE18905 [EO] KOG1046 Puromycin-sensitive aminopeptidase and related
aminopeptidases
Length = 747
Score = 207 bits (528), Expect = 4e-53
Identities = 159/593 (26%), Positives = 275/593 (45%), Gaps = 74/593 (12%)
Query: 1 MADVKIQTLPTDFRANHYEIELS--------ELDAEHNSFIGSVRIIMSTVNANDMISLN 52
+ADV LP +HY+I + + D +F G+V I++ D + L+
Sbjct: 24 IADVASYRLPRHVSPSHYDIHIKTYLPGYGWKADENKITFEGNVNILLDIKETTDKLVLH 83
Query: 53 MRDIEIVSAVVELKEGSVSLGMKDHSFDLENDVVSLKFPESISDDEFV-LKIDYKGMIQT 111
+ I+SA + E +VS+ + E+ ++ ++ ++I+++G ++T
Sbjct: 84 SSSLNIISATFQSDEQNVSIS--HWNVQTESQFLTFYLNNTVKVQSSAGIQINFQGKVRT 141
Query: 112 NMSGFYRSDYTDFVTGENKVMFSTQFEATDARRAFPCFDEPSLKATFDICIIAHEKYTVL 171
+ G + ++ T G F+TQFE AR PCFDEP KAT+++ + T L
Sbjct: 142 DGLGLFATNSTR-EDGTVMTNFATQFETIFARNMIPCFDEPEFKATWNVSLEHPTGSTAL 200
Query: 172 ANMPLKCTKKLTESDQISYRFHTTPLMSTYLVAWAVGEYDYIESETEKSIYPTIENYNTQ 231
+N ++ K+ + D + + T MS+Y++A +G+ + E TI N +
Sbjct: 201 SN-GIEVESKVND-DWKTTTYKKTLKMSSYILALFIGDIQFKE---------TILNNGVR 249
Query: 232 DGTSSGCGKLPVKVYTAKGKAQQGKFALDVAKRVIDFFSESFEIPYPLPKLDLLCVETYS 291
++VYT + AL++++ V++ F F I YP+ KLD + V+ +
Sbjct: 250 -----------IRVYTDPVNIDRVDHALNISRIVLEGFERQFGIRYPMEKLDFVSVQNFK 298
Query: 292 HNAMENFSLITFRPSALLYDGNLDEPDAAALQKIAYVVSHEIAHQWFGNLVTMKWWDELW 351
AMEN+ L+ +L+ D + +V HEIAHQWFGNLVTMK+WD +W
Sbjct: 299 FGAMENWGLVIHNAYSLIGDP----------MDVTEIVIHEIAHQWFGNLVTMKYWDHIW 348
Query: 352 LNEGFATWIGYLAVEKFFPDWDVPSMIMLQSHEVALELDSLKESHPIKVAVRNAKDIDQV 411
LNEGFA+++ + PD+ Q L + + V++ K++ V
Sbjct: 349 LNEGFASYMTSYGLTFLDPDY--------QRDTFYLNCQFNPQINDGGVSLNFGKNLSSV 400
Query: 412 FDSIS--YLKGCSILEMVSGYLGQELFLKGVALYLKRNKFSNATMEDLFNCI-------- 461
++ + Y+KGCS + M+ G E F + + YL++N++ N DL+
Sbjct: 401 MNNAATVYMKGCSFVRMLENIFGTEYFNEAIKFYLEKNQYDNVDDNDLYEAFRTSSETLD 460
Query: 462 --GEVADIEVLERCKNWILTIGYPLVTVTESEIGLSLTQNRFLSTGTCKPDEDVTKWWVP 519
G+ DIE RC W G+P + V+ +LTQ+ + D KW +P
Sbjct: 461 TNGKPFDIEKFARC--WTHQNGFPTIQVSNDNGIATLTQSHLYEPQLMLNECDY-KWDIP 517
Query: 520 LMPLQ-GDYKVDF-----SGKTTELPKTQFNHFNANSFGFYRVKYDSDHLFQQ 566
+ + G+ +V + + EL NANS G+Y V Y SD ++++
Sbjct: 518 IWYQEPGEARVQMAWLNRNSTSLELVADDSVIINANSIGYYEVLY-SDKMYEK 569
>CE20255 [EO] KOG1046 Puromycin-sensitive aminopeptidase and related
aminopeptidases
Length = 1045
Score = 204 bits (518), Expect = 6e-52
Identities = 150/455 (32%), Positives = 223/455 (48%), Gaps = 58/455 (12%)
Query: 99 FVLKIDYKGMIQTNMS-GFYRSDYTDFVTGENKVMFSTQFEATDARRAFPCFDEPSLKAT 157
+ L + +K I N++ G + + YT E + + +TQ + ++AR FPC D P +KA
Sbjct: 251 YTLDVAFKSAINLNLAYGLFAAPYT--FENETRYVVATQLQISEARTVFPCIDVPDMKAQ 308
Query: 158 FDICIIAHEKYTVLANMPLKCTKKLTESDQISYRFHTTPLMSTYLVAWAVGEYDYIESET 217
FD II T +ANM TK + + + FH TP MSTYL A++V +Y Y+E
Sbjct: 309 FDTVIIHPTGTTSIANMMENSTK--VDGEWTTTTFHRTPPMSTYLFAFSVSDYPYLE--- 363
Query: 218 EKSIYPTIENYNTQDGTSSGCGKLPVKVYTAKGKAQQGKFALDVAKRVIDFFSESFEIPY 277
T SG G + +VY K + V+DF+ + F IPY
Sbjct: 364 ----------------TFSGRG-VRSRVYCDPTKLVDAQLITKSIGPVLDFYEDYFGIPY 406
Query: 278 PLPKLDLLCVETYSHNAMENFSLITFRPSALLYDGNLDEPDAAALQK--IAYVVSHEIAH 335
PL KLD++ V S AMEN+ LIT R + LY E A QK + +V+HE+AH
Sbjct: 407 PLEKLDVVIVPALSVTAMENWGLITIRQTNGLYT----EGRFAISQKHDVQEIVAHELAH 462
Query: 336 QWFGNLVTMKWWDELWLNEGFATWIGYLAVEKFFPD--WDVPSMIMLQSHEVALELDSLK 393
QWFGNLVTMKWW++LWLNEGFAT I AV+ F + W +S VAL D +
Sbjct: 463 QWFGNLVTMKWWNDLWLNEGFATLISVRAVD-FLENTTWRYEDS-SAESQCVALRADQID 520
Query: 394 ESHPIKVAVRNAKDIDQVFD----SISYLKGCSILEMVSGYLGQELFLKGVALYLKRNKF 449
P V+ + + D + +I Y K I+ M+ + +++F +G+ +L +
Sbjct: 521 SISP--VSGKKNSNFDSYMEIQGKAIIYKKSAIIIRMIERLVEEDIFRQGLKRFLNTFLY 578
Query: 450 SNATMEDLFNCIGEVAD-----------IEVLERCKNWILTIGYPLVTVTESEIGL-SLT 497
NA EDLFN + V D + + WI +P++ V E L +L
Sbjct: 579 KNADHEDLFNVLVYVHDSSAGGHLRGQNFSLSDVMDTWIRQAHFPVIHVNRKEGSLVTLR 638
Query: 498 QNRFLSTGTCKPDEDVTKWWVPLM---PLQGDYKV 529
Q ++ +P++ V W +P+ P+ G +KV
Sbjct: 639 QEKYEHVPRDEPEKQV--WKIPIFYDDPVSGKHKV 671
>CE18904 [EO] KOG1046 Puromycin-sensitive aminopeptidase and related
aminopeptidases
Length = 786
Score = 195 bits (496), Expect = 2e-49
Identities = 181/596 (30%), Positives = 272/596 (45%), Gaps = 86/596 (14%)
Query: 24 ELDAEHNSFIGSVRIIMSTVNANDMISLNMRDIEIVSAVVELKEGSVSLGMKD--HSFDL 81
E D + +FIG V+I + D I L+ + I + + L V +K+ F L
Sbjct: 55 EADEKSFTFIGDVKIQIEVKEETDTIVLHTDSLNINNVL--LHNACVCANLKNLIQYFRL 112
Query: 82 ENDVVSLKFPESISDDEFVLKIDYKGMIQTNMSGFYR--SDYTDFVTGENKVMFSTQFEA 139
KF + G I+ + G+YR S + T N V TQFE
Sbjct: 113 ----AITKFENRQQTNSKYSLYGKIGKIREDGEGYYRTISPGLNETTMYNAV---TQFEP 165
Query: 140 TDARRAFPCFDEPSLKATFDICIIAHEKYTVLANMPLKCTKKLTESDQISYRFHTTPLMS 199
T AR PCFDEP KA + + ++ T L+N + T D + F +T MS
Sbjct: 166 TAARFMVPCFDEPEFKAIWHVTVVHPTGSTALSNAK-EIDNTKTNDDFSTTEFESTLKMS 224
Query: 200 TYLVAWAVGEYDYIESETEKSIYPTIENYNTQDGTSSGCGKLPVKVYTAKGKAQQGKFAL 259
+Y++A VG+ + E+ T+ + ++VY+ G AL
Sbjct: 225 SYILAIFVGDVQFKEAVTKNGVR--------------------IRVYSDPGHIDSVDHAL 264
Query: 260 DVAKRVIDFFSESFEIPYPLPKLDLLCVETYSHNAMENFSLITFRPSAL---LYDGNLDE 316
+V++ V++ F + F PY + KLDL+ V + + AMEN+ LI + L L GN D
Sbjct: 265 NVSRIVLEGFEKQFGYPYEMDKLDLIAVYNFRYGAMENWGLIVHQAYTLIENLMPGNTDI 324
Query: 317 PDAAALQKIAYVVSHEIAHQWFGNLVTMKWWDELWLNEGFATWIGYLAVEKFFPDWD--- 373
I+ VV+HEIAHQWFGNLVTMK+WD+LWLNEGFAT++ P++D
Sbjct: 325 --------ISEVVAHEIAHQWFGNLVTMKFWDQLWLNEGFATYMTAYGYTFLDPNYDRDY 376
Query: 374 ---VPSMIMLQSHEVALELDSLKESHPIKVAVRNAKDIDQVFDSISYLKGCSILEMVSGY 430
P +E+ +K SH A+ N S +Y KGCS + M+
Sbjct: 377 YYLSPQFESQSGNELGPLNSMIKLSHG---AIGN--------PSQNYAKGCSFIRMLEKI 425
Query: 431 LGQELFLKGVALYLKRNKFSNATMEDLFNCI----------GEVADIEVLERCKNWILTI 480
+G E F + + YL + FSN ++L++ + G+ DIE RC W
Sbjct: 426 VGTEHFNEAIRTYLHTHDFSNVEDKNLYDALRVYSDKLEINGKPFDIEEFGRC--WTHQT 483
Query: 481 GYPLVTVTESEIGLS-LTQNRFLSTGTCKPDEDVTKWWVPLMPLQ-GDYKVDFS-----G 533
GYP V V+ G + L+Q + T E KW +P+ Q G +V+ +
Sbjct: 484 GYPTVYVSSYYAGQTRLSQVKVKEIVTGDFHECNNKWDIPIWYQQSGSTEVELTWLEKDQ 543
Query: 534 KTTELPKTQFNHFNANSFGFYRVKYDSDHLFQQ---QLQNLDKL-SSRGKMGLISD 585
E+ T F NANS G Y V Y S+ L++Q +L+N ++ S+ K ++SD
Sbjct: 544 DELEINTTGFAIINANSNGLYDVVY-SEVLYEQVASELKNNTQMYSASTKARVLSD 598
>CE27507 [EO] KOG1046 Puromycin-sensitive aminopeptidase and related
aminopeptidases
Length = 1073
Score = 194 bits (492), Expect = 7e-49
Identities = 126/372 (33%), Positives = 190/372 (50%), Gaps = 41/372 (11%)
Query: 133 FSTQFEATDARRAFPCFDEPSLKATFDICIIAHEKYTVLANMP-LKCTKKLTESDQISYR 191
F+T+FE T AR FPC+DEP +KATF+I + ++KYTVL+NMP ++ + DQ
Sbjct: 238 FTTKFEPTLARAFFPCWDEPGVKATFNISVRHNKKYTVLSNMPPVESHDHKSWEDQFKTT 297
Query: 192 -FHTTPLMSTYLVAWAVGEYDYIESETEKSIYPTIENYNTQDGTSSGCGKLPVKVYTAKG 250
F TTP MSTYL+A+A+GE+ +ES TE+ I PV V+T
Sbjct: 298 VFQTTPPMSTYLLAFAIGEFVKLESRTERGI--------------------PVTVWTYPE 337
Query: 251 KAQQGKFALDVAKRVIDFFSESFEIPYPLPKLDLLCVETYSHNAMENFSLITFRPSALLY 310
KF L+ A + D ++ EIPYPLPK+DL+ + MEN+ L+ F +++ Y
Sbjct: 338 DVMSMKFTLEYAPVIFDRLEDALEIPYPLPKVDLIAARNFHVGGMENWGLVVFEFASIAY 397
Query: 311 DGNLDEPDAAALQK------IAYVVSHEIAHQWFGNLVTMKWWDELWLNEGFATWIGYLA 364
+ + + + I +++HE AHQWFGNLVTM+ W EL+LNEGFAT+ Y
Sbjct: 398 TPPITDHVNETVDRMYNEFRIGKLIAHEAAHQWFGNLVTMRDWSELFLNEGFATFYVY-- 455
Query: 365 VEKFFPDWDVPSMIMLQSHEVALELDSLKESHPIKVAVRNAKDIDQVFDSIS----YLKG 420
E + V + +L L +E H + + VR QV S Y KG
Sbjct: 456 -EMMSTERPVTAQFEYYDSLASLILAQSEEDHRLSL-VRELATESQVESSFHPTNLYTKG 513
Query: 421 CSILEMVSGYLGQELFLKGVALYLKRNKFSNATMEDLFNCIGEVAD-----IEVLERCKN 475
C ++ M+ + F V YL++N + + + +DLF + AD ++ +
Sbjct: 514 CVLIRMLRDLVSDFDFKAAVRRYLRKNAYRSVSRDDLFASLPAYADHGAEQEKLSHVLEG 573
Query: 476 WILTIGYPLVTV 487
W + G P +T+
Sbjct: 574 WFVNEGIPEITL 585
>7291179 [EO] KOG1046 Puromycin-sensitive aminopeptidase and related
aminopeptidases
Length = 931
Score = 191 bits (485), Expect = 4e-48
Identities = 171/662 (25%), Positives = 281/662 (41%), Gaps = 82/662 (12%)
Query: 18 YEIEL-SELDAEHNSFIGSVRIIMSTVNANDMISLNMRDIEIV---SAVVELKEG-SVSL 72
Y +++ + ++ + F G+V I + + + I LN D+ I + + K G SV +
Sbjct: 35 YRVDIVTRINQPYQPFGGTVVIDLRSERSTKRIVLNAHDLAIGKRRAVTLSDKNGNSVPV 94
Query: 73 GMKDHSFDLENDVVSLKFPESISDDEFVLKIDYKGMIQTNMSGFYRSDYTDFVTGENKVM 132
L VSLK P ++ + +++ + +++ + +GFY S+Y D T + +
Sbjct: 95 SSIQMDIKLSRLTVSLKRPLKVNVT-YSMRVAFTSVLRNDNTGFYSSNYVDHNTTLTQWL 153
Query: 133 FSTQFEATDARRAFPCFDEPSLKATFDICIIAHEKYTVLANMPLKCT-KKLTESDQISYR 191
+TQFE AR AFPCFD+P + F I + Y L+NMP++ T + + D + +
Sbjct: 154 AATQFEPNHAREAFPCFDDPIFRTPFKINLAHPYLYRALSNMPVQRTIRHASLKDYVWTQ 213
Query: 192 FHTTPLMSTYLVAWAVGEYDYIESETEKSIYPTIENYNTQDGTSSGCGKLPVKVYTAKGK 251
F + M TYLVA+ + ++D TSS P+ +
Sbjct: 214 FVESHPMQTYLVAFMISKFD------------------RPGFTSSERSDCPISTWARPDA 255
Query: 252 AQQGKFALDVAKRVIDFFSESFEIPYPLPKLDLLCVETYSHNAMENFSLITFRPSALLYD 311
Q +FA V ++ F+ + F Y K+DL+ + ++ + EN+ L F +LLYD
Sbjct: 256 LSQTEFANMVVAPLLSFYEDLFNSTYRQKKIDLVALPDFTFKSKENWGLPAFAEESLLYD 315
Query: 312 GNLDEPDAAALQKIAYVVSHEIAHQWFGNLVTMKWWDELWLNEGFATWIGYLAVEKFFPD 371
D Q +A V+ + +QWFGNLV++ WW E+WL FA ++ V P+
Sbjct: 316 SQRSSIDDQ--QGVARAVAMMVVNQWFGNLVSVAWWHEIWLKNVFALYLSRFGVHSLRPE 373
Query: 372 WDVPSMIMLQSHEVALELDSLKESHPIKVAVRNAKDIDQVFDSISYLKGCSILEMVSGYL 431
WD LQ + L+ D+ + + +V + I ++ I K + EM+ +
Sbjct: 374 WDYQERHALQLYLSVLDYDAHVNTDLVTASVPDESHIWAAYNEIGERKAAVLFEMLHRVM 433
Query: 432 GQELFLKGVALYLKRNKFSNATMEDLFNCIGEVAD--------IEVLERCKNWILTIGYP 483
G+E +L + YL AT D ++ + D + + K W+ GYP
Sbjct: 434 GEEAWLTALRRYLVVYANRTATSSDFWDLLQLQVDRNGRLGKGLNITRIMKCWLGQPGYP 493
Query: 484 LVTVTES--EIGLSLTQNRFLSTGTCKPDEDVTK-WWVPLM----PLQGDYKVDFSGKTT 536
LVTVT + ++Q RF T + WWVPL Q + FS T
Sbjct: 494 LVTVTRNYDHRTAIVSQQRFFITPQFRNRWARNPCWWVPLSYTCPSCQHSEIISFSRWLT 553
Query: 537 ------------------ELPKTQFNHFNANSFGFYRVKYDSDHLFQQQLQNLDKLSSRG 578
E T + FN +RV YD L QL N L+
Sbjct: 554 CPTSKPSSKSNTVLLEKLEAEPTDWILFNVQHTAPFRVNYD---LRNWQLLN-KTLADPN 609
Query: 579 KMGLISDVEVTECVKNLLTL-------------ISKFTNHQDPNDYYVW---SIIFDTLN 622
K LI V + V +L +L I + H+D ++ VW I F+ +N
Sbjct: 610 KFRLIHRVNRAQLVDDLFSLAWSGDIEYDMALGILGYLEHED--EFVVWVATEISFERIN 667
Query: 623 RM 624
+
Sbjct: 668 NV 669
>YIL137c [EO] KOG1046 Puromycin-sensitive aminopeptidase and related
aminopeptidases
Length = 946
Score = 179 bits (454), Expect = 2e-44
Identities = 157/592 (26%), Positives = 267/592 (44%), Gaps = 65/592 (10%)
Query: 16 NHYEIELSELDAEHNS--FIGSVRI----------IMSTVNANDMISLNMRDIEIVSAVV 63
+HYE+ L E+D + +S F GS I + S ++ L+ +D+ ++SA
Sbjct: 15 SHYELRL-EIDPKQSSPNFKGSAIIHLKFNPNSTTLASIEDSFTQFKLHSKDLIVLSAHA 73
Query: 64 ELKEGSVSLGMK-DHSFDLENDVVSLKFPESISDD-EFVLKIDYKGMIQTNMS------G 115
+ GS +K + + + P +S+D +L + Y G I+ + G
Sbjct: 74 TI--GSTKFDLKISQDTGKHLSIFNSESPIQLSNDCPLILSVQYVGKIRDIKTHHDKTFG 131
Query: 116 FYRSDYTDFVTGE-NKVMFSTQFEATDARRAFPCFDEPSLKATFDICIIAHEKYTVLANM 174
+++++ D TG N + +T + A FPC DEPS K+TF + I +Y ++N
Sbjct: 132 IFKTNFMDRKTGTANNHVVATHCQPFSASNIFPCIDEPSNKSTFQLNIATDAQYKAVSNT 191
Query: 175 PLKCTKKLTESDQISYRFHTTPLMSTYLVAWAVGEYDYIESETEKSIYPTIENYNTQDGT 234
P++ + L S + +F TPLM+T + +++G+ +++++E +
Sbjct: 192 PVEMVEALDSSQKHLVKFAKTPLMTTSVFGFSIGDLEFLKTEIK---------------- 235
Query: 235 SSGCGKLPVKVYTAKGKAQQGKFALDVAKRVIDFFSESFEIPYPLPKLDLLCVETYSHNA 294
G +PV +Y A F LD ++ + F+ PYPLPKLD + + S A
Sbjct: 236 LEGDRTIPVSIY-APWDIANAAFTLDTVQKYLPLLESYFKCPYPLPKLDFVLLPYLSDMA 294
Query: 295 MENFSLITFRPSALLYDGNLDEPDAAALQKIAYVVSHEIAHQWFGNLVTMKWWDELWLNE 354
MENF +IT + + LL N + Q +V HE+ HQW GN ++ W+ LW NE
Sbjct: 295 MENFGMITIQLNHLLIPPNALANETVREQAQQLIV-HELVHQWMGNYISFDSWESLWFNE 353
Query: 355 GFATWIGYLAVEK--FFPDWDVPSMIMLQSHEVALELDS--LKESHPIKVAVRNA---KD 407
FATW+ +E+ + +LQ E + D+ + ++A RN
Sbjct: 354 SFATWLACHILEQNGDLSHYWTSEPYLLQQVEPTMCRDAADVNGRSIFQIAQRNTGIDSQ 413
Query: 408 IDQVFDSISYLKGCSILEMVSGYLGQELFLKGVALYLKRNKFSNATM---EDLFNCIGE- 463
+FD +Y KG +L + G+ KG+ + K +A D++N IG+
Sbjct: 414 TSDIFDPEAYTKGIIMLRSLQLATGESHLQKGLESVFEDTKTFHARSVKPMDIWNHIGKF 473
Query: 464 VADIEVLERCKNWILTIGYPLVTV----TESEIGLSLTQNRF---LSTGTCKPDEDVTKW 516
+ + +W T G P+V V + + LTQ+RF LST EDV +
Sbjct: 474 LKSQNITNFVSSWTRTPGLPVVKVEVEEKDGKTQTKLTQHRFINQLSTEEKDQLEDV-PY 532
Query: 517 WVPLMPLQGDYKVDFSGKTTELPKTQFNH----FNANSFGFYRVKYDSDHLF 564
VPL + D K+D +F++ N + G+YRV Y+S+ +
Sbjct: 533 QVPLFGVLPDGKMDTKNVLLTDRTLKFDYPILVINHLAQGYYRVSYESEECY 584
>CE26001 [EO] KOG1046 Puromycin-sensitive aminopeptidase and related
aminopeptidases
Length = 1815
Score = 177 bits (450), Expect = 5e-44
Identities = 146/522 (27%), Positives = 239/522 (44%), Gaps = 72/522 (13%)
Query: 97 DEFVLKIDYKGMIQTNMS-GFYRSDYTDFVTGENKVMFSTQFEA-TDARRAFPCFDEPSL 154
+++ L I+Y G I N G + Y + +F+T FE AR PC+DEPS
Sbjct: 1101 NQYSLFIEYTGFIFQNPDEGDASNTYLGGLNNRKGWIFTTDFEGGPGARSLLPCWDEPSY 1160
Query: 155 KATFDICIIAHEKYTVLANMPLKCTKKLTESDQISYRFHTTPLMSTYLVAWAVGEYDYIE 214
K F++ + L+N + + + ++ + +F TT MSTYL+A VG + +
Sbjct: 1161 KGQFEVSVFHPTDMIALSN-EVDIQRTIYDNGWTTTKFATTNQMSTYLLALCVGHFSNLA 1219
Query: 215 SETEKSIYPTIENYNTQDGTSSGCGKLPVKVYTAKGKAQQGKFALDVAKRVIDFFSESFE 274
+ T + +V+T G Q G+FAL+V IDF F
Sbjct: 1220 TVTRTGVL--------------------TRVWTWSGMEQYGEFALNVTAGTIDFMENYFS 1259
Query: 275 IPYPLPKLDLLCVETYSHNA--MENFSLITFRPSALLYDGNLDEPDAAA---LQKIAYVV 329
+PL KLD++ + Y+ NA MEN+ LI S ++D PD A + ++A
Sbjct: 1260 YDFPLKKLDVMALPEYTMNAGAMENWGLIIGEYSLFMFD-----PDYATTRDITEVAETT 1314
Query: 330 SHEIAHQWFGNLVTMKWWDELWLNEGFATWIGYLAVEKFFPDWDVPSM--IMLQSHEVAL 387
+HE+ HQWFG++VT+ WW++++LNEGFA + ++ FP+ S+ + +AL
Sbjct: 1315 AHEVVHQWFGDIVTLDWWNDIFLNEGFAQYWFANGIDNTFPEQHAYSIDYNRFYMNHIAL 1374
Query: 388 ELDSLKESHPIKVAVRNAKDIDQVFDSISYLKGCSILEMVSGYLGQELFLKGVALYLKRN 447
+ D + VA D VF Y KG ++L +++ L +F +G++ YL +
Sbjct: 1375 KYDCIP-----GVAKPVISDTPPVFGIEPYYKGSALLNLLNNVLTPAVFQEGLSSYLTQY 1429
Query: 448 KFSNATMEDLFNCIGEVAD-----------IEVLERCKNWILTIGYPLVTVTESEIGLSL 496
+ NA+ +L+ + A ++V + L YP++T+T L
Sbjct: 1430 GYVNASPRNLWTSLTVAAQRHNITDWNGQPLDVSSFMDPYTLQTSYPIITLT-----LRG 1484
Query: 497 TQNRFLSTGTCKPDEDVTKWWVPLM-----PLQGDYKVDFSGKT-----TELPKTQFNHF 546
T + +C DE T W VPL L ++ V+F+G LP T +
Sbjct: 1485 TSTVQANQQSCMSDE--TLWNVPLFTQTPGALDFNWFVNFTGGNDATWLRPLP-TGYRVD 1541
Query: 547 NANSFGFYRVKYDSDHLFQ---QQLQNLDKLSSRGKMGLISD 585
NA S F R+ YD + Q L N++ +SS + L+ D
Sbjct: 1542 NAGSTSFARINYDDKSWYSIQAQLLSNMNTMSSTTRAMLLDD 1583
Score = 167 bits (423), Expect = 7e-41
Identities = 151/517 (29%), Positives = 233/517 (44%), Gaps = 67/517 (12%)
Query: 31 SFIGSVRIIMSTVNANDMISLNMRDIEIVSAVVELKEGSV----SLGMKDHSFDLE---- 82
+F G I + + A+D LN + +I S V +G+V S+ D + L
Sbjct: 112 TFDGRASIQVEALVASDRFILNAYNFKIQSYKVVDIDGTVVPINSISQDDTTQQLSLITN 171
Query: 83 -NDVVSLKFPESISDDEFVLKIDYKGMIQTNMSG-FYRSDYTDFVTGENKVMFSTQFEAT 140
N VV+ I + EFV Y G+I G Y + Y D G M +T E
Sbjct: 172 ANGVVA----GQIYNIEFV----YTGIINPYTDGGVYYTSYND-PQGNTHYMIATHMEPF 222
Query: 141 DARRAFPCFDEPSLKATFDICIIAHEKYTVLANMPLKCTKKLTESDQI--SYRFHTTPLM 198
AR+ FP DEPS KA F I + L+NM + T+ D I + F TP M
Sbjct: 223 SARKVFPSLDEPSYKAKFTITVQYPASQVALSNM---METEPTKIDNIWSTITFPQTPKM 279
Query: 199 STYLVAWAVGEYDYIESETEKSIYPTIENYNTQDGTSSGCGKLPVKVYTAKGKAQQGKFA 258
S+YL+A+AVG Y + S+ + +NT + + G Q +FA
Sbjct: 280 SSYLIAFAVGPY--VNSQY-------VNKHNTL-----------TRAWGWPGTEQYLQFA 319
Query: 259 LDVAKRVIDFFSESFEIPYPLPKLDLLCVETYSHNAMENFSLITFRPSALLYDGNLDEPD 318
A + E I +PL K D L + + AMEN+ LI ++ + Y N
Sbjct: 320 AQNAGECLYQLGEYTGIKFPLSKADQLGMPEFLAGAMENWGLIIYKYQYIAY--NPTTMT 377
Query: 319 AAALQKIAYVVSHEIAHQWFGNLVTMKWWDELWLNEGFATWIGYLAVEKFFPDWD--VPS 376
++ A V+ HE+AHQWFG+LVT WWD+L+LNEGFA + + +P + +
Sbjct: 378 TRNMEAAAKVMCHELAHQWFGDLVTTAWWDDLFLNEGFADYFMTFIQKSVYPQQATYLDT 437
Query: 377 MIMLQSHEVALELDSLKESHPIKVAVRNAKDIDQVFDSISYLKGCSILEMVSGYLGQELF 436
+ +L +V L D ++HP+ A FD I+Y KG S+L M+S LG ++F
Sbjct: 438 LQVLDELQVGLTADVRYDAHPLVYPDGPA------FDDITYNKGASMLRMLSDVLGADVF 491
Query: 437 LKGVALYLKRNKFSNATMEDLFNCIGEVA-----------DIEVLERCKNWILTIGYPLV 485
+G+ YL++ ++SNA DLF+ + + A + V + + +I +PL+
Sbjct: 492 KQGIRAYLQKMQYSNANDFDLFSTLTDTAKSNNILDWCGLPLNVTDFMQPYIHQTNHPLI 551
Query: 486 TVTESEI--GLSLTQNRFLSTGTCKPDEDVTKWWVPL 520
++ G + +Q FL W +PL
Sbjct: 552 RYNNNQKIGGSTFSQEPFLDISDLTATPWNYTWSIPL 588
>7291558 [EO] KOG1046 Puromycin-sensitive aminopeptidase and related
aminopeptidases
Length = 844
Score = 162 bits (410), Expect = 2e-39
Identities = 129/485 (26%), Positives = 221/485 (44%), Gaps = 60/485 (12%)
Query: 199 STYLVAWAVGEYDYIESETEKSIYPTIENYNTQDGTSSGCGKLPVKVYTAKGKAQQGKFA 258
STYLVA+AV + +EN T++ +S ++ + + Q +
Sbjct: 155 STYLVAFAVHD---------------LENAATEESKTSN--RVIFRNWMQPKLLGQEMIS 197
Query: 259 LDVAKRVIDFFSESFEIPYPLPKLDLLCVETYSHNAMENFSLITFRPSALLYDGNLDEPD 318
+++A +++ F+ F+I +PL K+D L V T+ AMEN+ L+T+ L N +
Sbjct: 198 MEIAPKLLSFYENLFQINFPLAKVDQLTVPTHRFTAMENWGLVTYNEERL--PQNQGDYP 255
Query: 319 AAALQKIAYVVSHEIAHQWFGNLVTMKWWDELWLNEGFATWIGYLAVEKFFPDWDVPSMI 378
A+ V+HE AHQWFGNLVTM WW++LWL EG +T+ GYLA++ P+W
Sbjct: 256 QKQKDSTAFTVAHEYAHQWFGNLVTMNWWNDLWLKEGPSTYFGYLALDSLQPEWRRGERF 315
Query: 379 MLQSHEVALELDSLKESHPIKVAVRNAKDIDQVFDSISYLKGCSILEMVSGYLGQELFLK 438
+ + DS I V+N ++ F Y KG + M+ +G+E F
Sbjct: 316 ISRDLANFFSKDSNATVPAISKDVKNPAEVLGQFTEYVYEKGSLTIRMLHKLVGEEAFFH 375
Query: 439 GVALYLKRNKFSNATMEDLFNCIGEVA--------DIEVLERCKNWILTIGYPLVTVTES 490
G+ +L+R F N DL+N + A D + +W L GYPLVT+ +
Sbjct: 376 GIRSFLERFSFGNVAQADLWNSLQMAALKNQVISSDFNLSRAMDSWTLQGGYPLVTLIRN 435
Query: 491 -EIG-LSLTQNRFLSTGTCKPDEDVTKWWVPLMPLQGDYKVDFSGKTTE----------- 537
+ G ++L Q+RF ++ + WWVPL ++ + DF+ T +
Sbjct: 436 YKTGEVTLNQSRFFQEHGI--EKASSCWWVPLRFVRQNLP-DFNQTTPQFWLECPLNTKV 492
Query: 538 ------LPKTQFNHFNANSFGFYRVKYDSDHLFQQQLQNLDKLSSRGKMGLISDVEVTEC 591
L ++ N +RV YD +H ++ +++L + G + ++ ++ +
Sbjct: 493 LKLPDHLSTDEWVILNPQVATIFRVNYD-EHNWRLIIESLRNDPNSGGIHKLNKAQLLDD 551
Query: 592 VKNLLTL-ISKFTNHQD-------PNDYYVWSIIFDTLNRMKSLLSSDKAVKKALDNFTL 643
+ L + + K+ D D+ W LNR+ +LL+ +A K N+
Sbjct: 552 LMALAAVRLHKYDKAFDLLEYLKKEQDFLPWQRAIGILNRLGALLNVAEANK--FKNYMQ 609
Query: 644 DLIQP 648
L+ P
Sbjct: 610 KLLLP 614
>7298258 [EO] KOG1046 Puromycin-sensitive aminopeptidase and related
aminopeptidases
Length = 578
Score = 157 bits (396), Expect = 9e-38
Identities = 125/488 (25%), Positives = 214/488 (43%), Gaps = 61/488 (12%)
Query: 99 FVLKIDY-KGMIQTNMSGFYRSDYTDFVTGENKVMFS-TQFEATDARRAFPCFDEPSLKA 156
+VL +++ + M G++ Y ++ T E K+ +S + F R P FDEPSLKA
Sbjct: 5 YVLSVEFGRPMTMDQRDGYFIRHYINWKTSE-KIWYSVSHFNRNWIRNTMPSFDEPSLKA 63
Query: 157 TFDICIIAHEKYTVLANMPLKCTKKLTESDQISYRFH-TTPLMSTYLVAWAVGEYDYIES 215
TF++ + H+++ NM ++ E + H TP + T+L+A++V
Sbjct: 64 TFNVTMGHHKRFQSYGNMKVQAVLPNREIQDYVWSVHEVTPTIPTHLLAFSVN------- 116
Query: 216 ETEKSIYPTIENYNTQDGTSSGCGKLPVKVYTAKGKAQQGKFALDVAKRVIDFFSESFEI 275
N+N + ++ + + + FA +A ++++F ++
Sbjct: 117 -----------NFNCRYSQAASLSPVRFRTCAQSADVRATSFAAQMAPQILEFLDRVLQV 165
Query: 276 PYPLPKLDLLCVETYSHNAMENFSLITFRPSALLY--DGNLDEPDAAALQKIAYVVSHEI 333
PL K+D L V+ + AMENF L+ +R LL DG + + L+ IA HE+
Sbjct: 166 ALPLEKIDQLVVDDFPTEAMENFGLVVYRSKHLLLREDGPMSKEKLQTLELIA----HEM 221
Query: 334 AHQWFGNLVTMKWWDELWLNEGFATWIGYLAVEKFFPDWDVPSMIMLQSHEVALELDSLK 393
AH WF NL+ M + +LWL EG A + LAV+ + I+L+ E ++ +S
Sbjct: 222 AHMWFDNLLGMDSYSDLWLTEGLAGYFKSLAVDHL--QSKMGRRILLRYRESSMMYESQV 279
Query: 394 ESHPIKVAVRNAKDIDQVFDSISYLKGCSILEMVSGYLGQELFLKGVALYLKRNKFSNAT 453
+ NA ++ Y K S+ M+ G+LG E F G+ ++ +N F ++T
Sbjct: 280 GGISLVPLSSNA---SLNAETQLYQKATSLTSMLIGFLGNETFYDGLQRHMWQNSFGSST 336
Query: 454 MEDLFNCIGEVADIE--------VLERCKNWILTIGYPLVTVTESEIGLSLTQNRFLSTG 505
+ + + ++ E V W + GYPLVTV + + L Q L+
Sbjct: 337 PDLFWRSLQLASEREATFDKTWDVKSIMDTWTMQSGYPLVTVIRNGSEVFLKQGHALNRS 396
Query: 506 TCKPDEDVTKWWVPLMPL--QGDYKVDFSGK------------TTELPKTQFNHFNANSF 551
+ WW+PL L G + K +P+ Q+ N +
Sbjct: 397 SSH------LWWIPLTYLIEGGSLSKNLKPKAWLSPNSHGIKLNDIVPRNQWILLNLQAV 450
Query: 552 GFYRVKYD 559
G+YRV YD
Sbjct: 451 GYYRVNYD 458
>7291178 [EO] KOG1046 Puromycin-sensitive aminopeptidase and related
aminopeptidases
Length = 911
Score = 133 bits (334), Expect = 1e-30
Identities = 109/437 (24%), Positives = 194/437 (43%), Gaps = 46/437 (10%)
Query: 97 DEFVLKIDYKGMIQTNMSGFYRSDYTDFVTGENKVMFSTQFEATDARRAFPCFDEPSLKA 156
+E+ L + + G + + SG++ Y D + TQ A FPCF+ + A
Sbjct: 116 EEYTLVVQFSGQL-SRASGYFVGGYMDSKHHPQWIAV-TQLAPNLANTVFPCFENRTFLA 173
Query: 157 TFDICIIAHEKYT-VLANMPLKCTKKLTESDQISYRFHTTPLMSTYLVAWAVGEYDYIES 215
F I +AH + T ++NM + T + D + F TP MS +A+++ +
Sbjct: 174 PF-ILNLAHPRGTNAVSNMRVLKTSDHEKDDYVWTTFQQTPAMSVQKLAFSINRFT---- 228
Query: 216 ETEKSIYPTIENYNTQDGTSSGCGKLPVKVYTAKGK-AQQGKFALDVAKRVIDFFSESFE 274
+ TS+ K P + K A QG +A+ + ++I FF F
Sbjct: 229 ----------------NRTSAEIPKGPALTTWLRPKIADQGDYAISITPQIIVFFISLFG 272
Query: 275 IPYPLPKLDLLCVETYSHNAMENFSLITFRPSALLYDGNLDEPDAAALQKIAYVVSHEIA 334
PYP K+D L + ++ + E+ L+++ +A LY + A Q++A V+ E A
Sbjct: 273 KPYPAMKIDQLVLPDTAYQSHEHLGLVSYPEAAFLY--SAQRSTTRAKQQVASHVAQEFA 330
Query: 335 HQWFGNLVTMKWWDELWLNEGFATWIGYLAVEKFFPDWDVPSMIMLQSHEVALELDSLKE 394
H W +L + WL+ G + ++ AV+ P W + M++ L DS
Sbjct: 331 HHWLSDLENAALY---WLHNGLSDYVSGFAVDNVEPAWRFHELSMVRQALAVLVEDSKSS 387
Query: 395 SHPIKVAVRNAKDIDQVFDSISYLKGCSILEMVSGYLGQELFLKGVALYLKR-NKFSNAT 453
++P+ +A + D+ + K + M+ +G + FL + LYL+R +K S++
Sbjct: 388 AYPMSLAYASKSS-----DTQANQKSALLFRMLHSLIGTQAFLNALRLYLQRSHKGSSSN 442
Query: 454 MEDLFNCIGEVA--------DIEVLERCKNWILTIGYPLVTVTES--EIGLSLTQNRFLS 503
L++ + E + DI+V + +W + GYPL+ V + +++TQ RFL
Sbjct: 443 QAFLWHTLQEESDNQMSLRQDIKVSQLMDSWTMQPGYPLIRVVRNYDTNEVTVTQERFLR 502
Query: 504 TGTCKPDEDVTKWWVPL 520
+ WWVPL
Sbjct: 503 NPGKLMQKRQQCWWVPL 519
>CE13593 [EO] KOG1046 Puromycin-sensitive aminopeptidase and related
aminopeptidases
Length = 556
Score = 110 bits (275), Expect = 9e-24
Identities = 115/474 (24%), Positives = 194/474 (40%), Gaps = 75/474 (15%)
Query: 129 NKVMFSTQFEATDARRAFPCFDEPSLKATFDICIIAHEKYTVLANMPLKCTKKLTESDQI 188
N ++++T + ARR FPC D P++KA F + I+ H TV + + +
Sbjct: 45 NPLLYTTHLQPNHARRLFPCIDHPAVKALFRLSIV-HPTDTVAQSNTIAMDVHVENRKWQ 103
Query: 189 SYRFHTTPLMSTYLVAWAVGEYDYIESETEKSIYPTIENYNTQDGTSSGCGKLPVKVYTA 248
F TPL+ YLVA++V ++ + S T+ +G S G L ++V
Sbjct: 104 RTIFQATPLLPAYLVAFSVMPDSNLQLSRQTSFGVTVR----VNGESRG---LVLRV--- 153
Query: 249 KGKAQQGKFALDVAKRVIDFFSESFEIPYPLPKLDLLCVETYSHNAMENFSLITFRPSAL 308
LD A + + ++P PL K+D + V Y MEN+ IT + L
Sbjct: 154 ----------LDCALASFEILAGLIDVPLPLNKIDFILVPEYD-GGMENWGHITVSET-L 201
Query: 309 LYDGNLDEPDAAALQKIAYVVSHEIAHQWFGNLVTMKWWDELWLNEGFATWIGYLAVEKF 368
G+ DA + Y+++HEIAH W GN T+ W+ + L E W+ AV+
Sbjct: 202 ATSGD----DA----HLIYLIAHEIAHHWIGNRATIDSWNWICLQEDLTDWMALKAVKAL 253
Query: 369 FPD-WDVPSMIMLQSHEVALELDSLKESHPIKVAVRNAKDIDQVFDSISYLKGCSILEMV 427
D + + Q E+ L D L H + + +K ++ + YLKG +L+ +
Sbjct: 254 LTDEIRLQRFQLAQYVEIQLVEDFLSPGHSLYMP---SKINQELINRHCYLKGVVLLDTL 310
Query: 428 SGYLGQELFLKGV-ALYLKRNKFSNATMEDLFNCIGEVADIEVLERCKNWILTIGYPLVT 486
+G++ + +L + ++ T F+ I + V + + W T GYP +
Sbjct: 311 ESVVGEQFMYSVIKSLVGSHSTYNLTTFTSYFDQIRVDRNATVGQIYEYWYTTGGYPSIL 370
Query: 487 VTESEIGLSLTQNRFLSTGTCKPDEDVTKWWVPLMPLQGDYKVDFSGKTTELPKTQFNH- 545
V + P + + PL PL+ T +P+ F+
Sbjct: 371 VENN-----------------GPSSRLQQLSRPLWPLK-------MTSTLAIPQFVFSES 406
Query: 546 -----------FNANSFGFYRVKYDS---DHLFQQQLQNLDKLSSRGKMGLISD 585
N N F RV YDS +F+ + + S+ G+ L+SD
Sbjct: 407 IVFASENAPLLVNLNFTSFMRVNYDSLTWTAIFKYMFEEPELFSAVGRAQLVSD 460
>CE05135 [EO] KOG1046 Puromycin-sensitive aminopeptidase and related
aminopeptidases
Length = 1071
Score = 108 bits (271), Expect = 3e-23
Identities = 128/531 (24%), Positives = 219/531 (41%), Gaps = 73/531 (13%)
Query: 79 FDLENDVVSLKFPESISDDE-FVLKIDYKGMIQTNMSGFYRSDYTDFVTGENKVMFSTQF 137
FD + V+L + + VLKI + + N +G Y + G+ + MF+TQ
Sbjct: 274 FDENLEKVTLTLDQELKKGSTVVLKIPFTSKVSNN-NGLKEYKYKNS-EGKEQSMFTTQP 331
Query: 138 EATDARRAFPCFDEPSLKATFDICIIAHEKYTVLANMPLKCTKKLTESDQISYRFHTTPL 197
+ R FP FD+ + KA I ++ + V+AN +K T+ D + T+ L
Sbjct: 332 SYSYLRHVFPSFDQEAFKAPAAITLMHSKGSIVVANTGVK-----TKDDGDA---QTSTL 383
Query: 198 MSTYLVAWAVGEYDYIESETEKSIYPTIENYNTQDGTSSGCGKLPVKVYTAKGKAQQGKF 257
+ +G D + SE T+SG + ++++T +
Sbjct: 384 NKVLDPDFVIG--DLVASEVN---------------TTSG---ITIRIWTRPEVKHSTEQ 423
Query: 258 ALDVAKRVIDFFSESFEIPYPLPKLDLLCVETYSHNAMENFSLITFRPSALLYDGNLDEP 317
+LD A + ID + LD++ V + + S I +LY N
Sbjct: 424 SLDYANQAIDAMEHILQSRLESKSLDIVAVPGFQTGNRVSPSFIVLPEEDILY--NEQSN 481
Query: 318 DAAALQKIAYVVSHEIAHQWFGNLVTMKWWDELWLNEGFATWIGYLAVEKFFPDWDVPS- 376
D +IA ++S+ IA QWFG + + + WLNE ++ A+EK D+ S
Sbjct: 482 DINQKTRIARMISNRIAAQWFGGITNPEEFGTFWLNEALPRFLEVEALEKIL---DINSD 538
Query: 377 MIMLQSHEVALELDSLKESHPIKVA-VRNAKDIDQVFDSISYLKGCSILEMVSGYLGQEL 435
+ E LE D+ S P++V V ++ DI ++ KG ++L M+ +G +
Sbjct: 539 DLWTYEMEKILERDATATSQPLRVKNVFSSADIAEIDHEFIGKKGAAVLRMIQKSVGVNV 598
Query: 436 FLKG----VALYLKRNKFSNATMEDLFNCIG------EVADIEVLERCKNWILTIGYPLV 485
F K V+ Y + + + +G ++V + W+ IG+PLV
Sbjct: 599 FNKAIRSFVSSYRSAYPYDDGLWKSFEKALGGKLKGWNNEPLDVAKFVNTWVDQIGFPLV 658
Query: 486 TVTE-SEIGLSLTQNRFLSTGTCKPDEDVT------KWWVPLMPLQGDYKVDFSGKTTEL 538
+V + + + L+Q RF + K W VPL+PL +
Sbjct: 659 SVEKLDDETVELSQERFKNDHKTKEQFKFRNAKYWFNWEVPLLPLNTSDSI--------- 709
Query: 539 PKTQFNHFNANSFGFYRVKYDS---DHLFQQQLQNLDKLSSRGKMGLISDV 586
+ N +S G YRV Y+ + + +Q ++ KLS R + LISDV
Sbjct: 710 ------YLNTDSNGVYRVNYEEKRWNDIAKQLEKSHGKLSERTRARLISDV 754
>Hs4505029 [IOVE] KOG1047 Bifunctional leukotriene A4 hydrolase/aminopeptidase
LTA4H
Length = 611
Score = 97.4 bits (241), Expect = 8e-20
Identities = 113/509 (22%), Positives = 211/509 (41%), Gaps = 80/509 (15%)
Query: 14 RANHYEIELSELDAEHNSFIGSVRIIMSTVNAN-DMISLNMRDIEIVSAVVELKEGSVSL 72
R H + S +D + G+ + + + N + L+ +D+ I V+ +E +L
Sbjct: 18 RTKHLHLRCS-VDFTRRTLTGTAALTVQSQEDNLRSLVLDTKDLTIEKVVINGQEVKYAL 76
Query: 73 GMKDHSFDLENDVVSLKFPESIS-DDEFVLKIDYKGMIQTNMSGFYRSDYTDFVTGENKV 131
G + + + + P ++S + E V++I ++ +++ + + T +G+
Sbjct: 77 GERQ---SYKGSPMEISLPIALSKNQEIVIEISFETSPKSSALQWLTPEQT---SGKEHP 130
Query: 132 MFSTQFEATDARRAFPCFDEPSLKATFDICI-IAHEKYTVLANMPLKCTKKLTESDQISY 190
+Q +A R PC D PS+K T+ + + E +++ + T + + Y
Sbjct: 131 YLFSQCQAIHCRAILPCQDTPSVKLTYTAEVSVPKELVALMSAIRDGETPDPEDPSRKIY 190
Query: 191 RFHTTPLMSTYLVAWAVGEYDYIESETEKSIYPTIENYNTQDGTSSGCGKLPVKVYTAKG 250
+F + YL+A VG + + I P V++ K
Sbjct: 191 KFIQKVPIPCYLIALVVGALE------SRQIGPR------------------TLVWSEKE 226
Query: 251 KAQQGKFALDVAKRVIDFFSESFEIPYPLPKLDLLCVE-TYSHNAMENFSLITFRPSALL 309
+ ++ + + ++ +E PY + DLL + ++ + MEN L P+ L
Sbjct: 227 QVEKSAYEFSETESMLKI-AEDLGGPYVWGQYDLLVLPPSFPYGGMENPCLTFVTPTLLA 285
Query: 310 YDGNLDEPDAAALQKIAYVVSHEIAHQWFGNLVTMKWWDELWLNEGFATWI-----GYLA 364
D +L V++HEI+H W GNLVT K WD WLNEG ++ G L
Sbjct: 286 GDKSLSN-----------VIAHEISHSWTGNLVTNKTWDHFWLNEGHTVYLERHICGRLF 334
Query: 365 VEKF-----FPDWDVPSMIMLQSHEVALELDSLKESHPIKVAVRNAKDIDQ--VFDSISY 417
EKF W E+ + + E+HP V + DID + S+ Y
Sbjct: 335 GEKFRHFNALGGWG----------ELQNSVKTFGETHPFTKLVVDLTDIDPDVAYSSVPY 384
Query: 418 LKGCSILEMVSGYL-GQELFLKGVALYLKRNKFSNATMED----LFNCIGEVADIEVLER 472
KG ++L + L G E+FL + Y+++ + + T +D L++ + D+
Sbjct: 385 EKGFALLFYLEQLLGGPEIFLGFLKAYVEKFSYKSITTDDWKDFLYSYFKDKVDVLNQVD 444
Query: 473 CKNWILTIGYPLV------TVTESEIGLS 495
W+ + G P + T+T + I LS
Sbjct: 445 WNAWLYSPGLPPIKPNYDMTLTNACIALS 473
>YNL045w [IOVE] KOG1047 Bifunctional leukotriene A4 hydrolase/aminopeptidase
LTA4H
Length = 671
Score = 94.4 bits (233), Expect = 7e-19
Identities = 101/428 (23%), Positives = 179/428 (41%), Gaps = 56/428 (13%)
Query: 12 DFRANHYEIELSELDAEHNSFIGSVRIIMSTVNANDMISLNMRDIEIVSAVVELKEGSVS 71
DF H ++ LS + E ++ GSV + ++ S ++ + ++ ++++E +
Sbjct: 66 DFAVLHTDLNLS-VSFEKSAISGSVTFQLKKLHEGKNKS---DELHLDTSYLDVQEVHID 121
Query: 72 LGMKDHSFDLENDVVS--LKFPESISDDEFVLKIDYKGMIQTNMSGFYRSDYTDFVTGEN 129
D + + + L + +D F L I ++ + + S T G
Sbjct: 122 GSKADFQIEQRKEPLGSRLVINNASCNDNFTLNIQFRTTDKCTALQWLNSKQTK---GGK 178
Query: 130 KVMFSTQFEATDARRAFPCFDEPSLKATFDICIIAHEKYTVLANMPLKCTKKLTESDQIS 189
+FS Q EA AR FPCFD PS+K+TF I + V + + ++ T K D
Sbjct: 179 PYVFS-QLEAIHARSLFPCFDTPSVKSTFTASIESPLP-VVFSGIRIEDTSK----DTNI 232
Query: 190 YRFHTTPLMSTYLVAWAVGEYDYIESETEKSIYPTIENYNTQDGTSSGCGKLPVKVYTAK 249
YRF + YL+ A G+ ++Y E + +D C
Sbjct: 233 YRFEQKVPIPAYLIGIASGDLSSAPIGPRSTVYT--EPFRLKD-----C----------- 274
Query: 250 GKAQQGKFALDVAKRVIDFFSESFEIPYPLPKLDLLC-VETYSHNAMENFSLITFRPSAL 308
Q +F DV K + +E Y D+L V++Y + ME+ ++ P+ +
Sbjct: 275 ----QWEFENDVEKFIQT--AEKIIFEYEWGTYDILVNVDSYPYGGMESPNMTFATPTLI 328
Query: 309 LYD-GNLDEPDAAALQKIAYVVSHEIAHQWFGNLVTMKWWDELWLNEGFATWIGYLAVEK 367
+D N+D V++HE+AH W GNLVT W+ WLNEG+ ++ +
Sbjct: 329 AHDRSNID------------VIAHELAHSWSGNLVTNCSWNHFWLNEGWTVYLERRIIGA 376
Query: 368 FFPDWDVPSMIMLQSHEVALELDSLKESHPIKVAVRNAK---DIDQVFDSISYLKGCSIL 424
+ ++ ++ +DS+K+ V+N D D F ++ Y KG ++L
Sbjct: 377 IHGEPTRHFSALIGWSDLQNSIDSMKDPERFSTLVQNLNDNTDPDDAFSTVPYEKGFNLL 436
Query: 425 EMVSGYLG 432
+ LG
Sbjct: 437 FHLETILG 444
>7300975 [EO] KOG1046 Puromycin-sensitive aminopeptidase and related
aminopeptidases
Length = 1114
Score = 91.7 bits (226), Expect = 5e-18
Identities = 101/478 (21%), Positives = 189/478 (39%), Gaps = 76/478 (15%)
Query: 173 NMPLKCTKKLTESDQISY--RFHTTPLMSTYLVAWAVGEYDYIESETEKSIYPTIENYNT 230
N P++ LT S ++ R + T + T AW V + + S ++
Sbjct: 372 NPPVRNITALTHSLNVNLTPRQNLTVVQPTTTTAWPVN----LNGNGKPSNLTSLSQ--- 424
Query: 231 QDGTSSGCGKLP-VKVYTAKGKAQQGKFALDVAKRVIDFFSESFEIPYPLPKLDLLCVET 289
T S + P Y + + F L ++ V+++ +I YPL K+D + + +
Sbjct: 425 --STGSSIKRAPSYTFYAPRDLLIRSSFILHTSRDVLEYLQTWLDISYPLTKVDFVALPS 482
Query: 290 YSHNAMENFSLITFRPSALLYDGNLDEPDAAALQKIAYVVSHEIAHQWFGNLVTMKWWDE 349
N + + L+T + S L ++ Q A ++ + Q+FG + + K +
Sbjct: 483 LDRNMISSLGLVTLKTSFLTDPSSITSEQ---YQFSALRIAEAMVRQFFGGITSRKVLKD 539
Query: 350 LWLNEGFATWIGYLAVEKFFPDWDVPSMIMLQSHEVALELDSLKESHPIKVAVRNAKDID 409
+WL EG ++G A+ W + M +L+ AL++D+++ ++ N D
Sbjct: 540 VWLWEGLIQYLGIHALAPLQETWPLREMYLLKMATAALDIDAIQGWD----SIMNGTSHD 595
Query: 410 QVFDSISYLKGCSILEMVSGYLGQELFLKGVALYLKRNKFSNATMEDLFNCIGEVAD--I 467
+ K +I M+ +G++ F + +LK N+F A DL+ + A+
Sbjct: 596 GNNEEFFVQKTAAIFSMLHTAIGEDRFRGCLGSFLKVNRFRTAEPTDLWTICTKKANGSK 655
Query: 468 EVLERCKNWILTIGYPLVTVTESEIGLSLTQ---------------------NRFLSTGT 506
+ + W G+PL+TVT+ +S++Q N+ T
Sbjct: 656 NIKDMMTLWTHQPGFPLLTVTKMGNSISISQRPFRPAEFLAIHDDSYDGNNYNKTTLNAT 715
Query: 507 CKPDEDVT-------------KWWVPLMPLQGDYKVDFSGKTTEL------------PKT 541
P T KW P+ Y D + + L
Sbjct: 716 DMPSTVATTTQGSKHKVAPHMKWIFPV-----TYVTDINNVSETLWMQNVDVTFNVPENV 770
Query: 542 QFNHFNANSFGFYRVKYDSDH---LFQQQLQNLDKLSSRGKMGLISDVEVTECVKNLL 596
++ NA G+YRV Y+ D+ L ++ N ++ +S ++G++SD T C NLL
Sbjct: 771 KWIKVNAIQNGYYRVVYNDDNWASLIEELAANPNRFTSEDRLGMLSDA-FTLCHANLL 827
Score = 59.3 bits (142), Expect = 3e-08
Identities = 55/234 (23%), Positives = 95/234 (40%), Gaps = 33/234 (14%)
Query: 9 LPTDFRANHYEI----ELSELDAEHNSFIGSVRIIMSTVNANDMISLNMRDIEIVSAVVE 64
LPT R Y + L+ LD + G V I + + I L+++D+ + +
Sbjct: 127 LPTSVRPLRYMVTIHPNLTTLDVK-----GQVTIDLHVEKETNFIVLHIQDLNVTEKAI- 180
Query: 65 LKEGSVSLGMKDHSFDLENDVVSLKFPESIS-----------DDEFVLKIDYKGMIQTNM 113
V+ G K ++ + V L+FP + L + + +
Sbjct: 181 -----VTPGPKGYALKI---VKVLEFPPRQQLYIEVKERLKKKSNYTLNLRWYSKLNPEP 232
Query: 114 SGFYRSDYTDFVTGENKVMFSTQFEATDARRAFPCFDEPSLKATFDICIIAHEKYTVLAN 173
GFY Y + G +++ +T F ARRAFPCFDEP ++A F I + + L+N
Sbjct: 233 EGFYVDQY-ESSNGVERLLAATVFRPNGARRAFPCFDEPHVRAPFRISVFRDRFHIGLSN 291
Query: 174 MPLKCTKKL---TESDQISYRFHTTPLMSTYLVAWAVGEYDYIESETEKSIYPT 224
+ T+ + + + F TP + VAW V ++ + + PT
Sbjct: 292 SIVHTTEDVGFYMGTGLLRDDFIETPPLPADAVAWVVSDFQRESLQPSAAYIPT 345
>7298498 [IOVE] KOG1047 Bifunctional leukotriene A4 hydrolase/aminopeptidase
LTA4H
Length = 613
Score = 91.3 bits (225), Expect = 6e-18
Identities = 108/443 (24%), Positives = 182/443 (40%), Gaps = 58/443 (13%)
Query: 24 ELDAEHNSFIGSVRIIMSTVNAN-DMISLNMRDIEIVSAVVELKEGSVSLGMKDHSFDLE 82
++D GSV + AN D I L++RDI + +A L G L + D
Sbjct: 28 KIDFAATKIQGSVLHRFKVLTANLDKILLDVRDINVTNAT--LLAGGSELPINFFISDAV 85
Query: 83 NDV---VSLKFPESISDDEFVLKIDYKGMIQTNMSGFYRSDYTDFVTGENKVMFSTQFEA 139
+D+ ++L+ P + ++IDY+ ++ SG + T + E+ MFS Q +A
Sbjct: 86 DDIGQKLTLELPSGTAKGSLNVRIDYE--TSSSASGLQWLNPTQTLGKEHPYMFS-QCQA 142
Query: 140 TDARRAFPCFDEPSLKATFDICIIAHEKYTVLANMPLKCTKKLTESDQISYRFHTTPLMS 199
AR PC D P++K T+D + + T L + + + + F +
Sbjct: 143 IHARSVIPCQDTPAVKFTYDATVEHPSELTALMSA------LIDKKEPGKTLFKQEVPIP 196
Query: 200 TYLVAWAVGEYDYIESETEKSIYPTIENYNTQDGTSSGCGKLPVKVYTAKGKAQQGKFAL 259
YLVA A+G+ S++ ++ C A++
Sbjct: 197 AYLVAIAIGKLVSRPLGENSSVW-------AEEAIVDAC-------------AEEFSETA 236
Query: 260 DVAKRVIDFFSESFEIPYPLPKLDLLCVE-TYSHNAMENFSLITFRPSALLYDGNLDEPD 318
+ K + PY + DLL + ++ MEN L P+ L D +L
Sbjct: 237 TMLKTATELCG-----PYVWKQYDLLVMPPSFPFGGMENPCLTFVTPTLLAGDKSL---- 287
Query: 319 AAALQKIAYVVSHEIAHQWFGNLVTMKWWDELWLNEGFATWIGYLAVEKFFP----DWDV 374
A VV+HEIAH W GNLVT K ++ WLNEGF ++ V + D+ +
Sbjct: 288 -------ADVVAHEIAHSWTGNLVTNKNFEHFWLNEGFTVFVESKIVGRMQGAKELDFKM 340
Query: 375 PSMIMLQSHEVALELDSLKESHPIKVAVRNAKDIDQVFDSISYLKGCSILEMVSG-YLGQ 433
S + + +L+ E + V + N D F S+ Y+KG + L + + G
Sbjct: 341 LSNLTDLQECIRTQLNKTPELTKLVVDLSNCGP-DDAFSSVPYIKGSTFLRYLEDLFGGP 399
Query: 434 ELFLKGVALYLKRNKFSNATMED 456
+F + YLK+ + + +D
Sbjct: 400 TVFEPFLRDYLKKYAYKSIETKD 422
>7294697 [EO] KOG1046 Puromycin-sensitive aminopeptidase and related
aminopeptidases
Length = 887
Score = 90.9 bits (224), Expect = 8e-18
Identities = 149/707 (21%), Positives = 278/707 (39%), Gaps = 88/707 (12%)
Query: 28 EHNSFIGSVRIIMSTVNANDMISLNMRDIEIVSAVVEL-------KEGSVSLGMKDHSFD 80
E N F G V I + +I LN +I I + K G++ +
Sbjct: 40 EQNQFEGIVSIDIEATQPTRVIYLNSLNITISRQRTWIYRWASGRKIGALQIKRIIKKTS 99
Query: 81 LENDVVSLKFPESISDDEFVLKIDYKGMIQTNMSGFYRSDYTDFVTGENKVMFS-TQFEA 139
L V+ L S + + L + + G + + Y + Y D +V +S T+ E
Sbjct: 100 LIKIVIELPLR---SGEIYTLNMLFSGNLDRSQQYGYFAGYYDKTP---RVFYSATRLEP 153
Query: 140 TDARRAFPCFDEPSLKATFDICIIAHEKYTVLANMPLKCTKKLTESDQ-ISYRFHTTPLM 198
A FPCFD+P + ++I ++ KY L+NMP K E + +S F +P +
Sbjct: 154 DYAHTVFPCFDDPRFRTPYNITLVHDRKYVALSNMPPVEEKPYKEIENYVSTTFMGSPPL 213
Query: 199 STYLVAWAVGEYDYIESETEKSIYPTIENYNTQDGTSSGCGKLPVKVYTAKGKAQQGKFA 258
+T V W + + + + S P N + V++ A++
Sbjct: 214 ATQQVMWTLHQLEKVYSG------PAAAGEN-------------ITVWSRPHLAEKLAKV 254
Query: 259 LDVAKRVIDFFSESFEIPYPLPKLDLLCVETYSHNAMENFSLITFRPSALLYDGNLDEPD 318
++ + + F YPLPK H + ++ + ++Y ++ +
Sbjct: 255 PEMTPNLFSKYETLFA--YPLPK-GADWGGKVDHVVLPRYTEMYSGQGIMVYGEDIVDSG 311
Query: 319 AAALQKIAYVVSHEIAHQWFGNLVTMKWWDELWLNEGFATWIGYLAVEKFFPDWDVPSMI 378
L+ + ++ +A QW G LV ++ DE ++ G YL+V+ D + +
Sbjct: 312 QNGLESLQETLAELVARQWNGLLVNLEDSDEEYVRNGINY---YLSVQVMAMDKEAYNTT 368
Query: 379 MLQSHEV-ALELDSLKESHPIKVAVRNAKDIDQVFDSISYLKGCSILEMVSGYLGQELFL 437
L + L DSL + I V+ + + K C ++ M+ LG +LFL
Sbjct: 369 HLSKTRLDVLYHDSLAKVKSIATDVKESGH-----QKLRKKKMCLLIHMLKVALGDKLFL 423
Query: 438 KGVALYLKRNKFSNATMEDLFNCIGEVA--------DIEVLERCKNWILTIGYPLVTVTE 489
KG+ + KR S+A+ ++L+ A + + ++W+ G+PL+TV
Sbjct: 424 KGLQEFFKRYANSSASSKELWEEFQRGARRSHQLPTGVSLPTVMESWMKQPGFPLLTVQR 483
Query: 490 SEIG--LSLTQNRFLSTGTCKPDEDVTKWWVPLMPLQGDY---KVDFSG-KTTELPKTQF 543
+ +++TQ+R+ D WWVP+ + + +V++ G + +
Sbjct: 484 DDAKQIVTITQSRYYQKYLDNSSNDC--WWVPVAYIVRNLTLPQVEWLGCQKNSRDILEL 541
Query: 544 NH---------FNANSFGFYRVKYDSDHL---FQQQLQNLDKLSSRGKMGLISDVEVTEC 591
+H N ++ RV YDS +L + Q+ ++ ++ L+ D
Sbjct: 542 SHIANPEDWLLINVDAAVPLRVFYDSYNLQLISEALRQDFTQIPELSRIQLVDDALSLSW 601
Query: 592 VKNL-----LTLISKFTNHQDPNDYYVWSIIFDTLNRMKSLLSSDKAVKKALDNFTLDLI 646
L L +IS +N VW L +++S++ + + LI
Sbjct: 602 SGRLPYNVTLNVISYLSNE---TSVLVWETALLNLEKLQSIMRMTTGF-RIFKLYMQKLI 657
Query: 647 QPSIEKLLEFLDQQKTNSFSKNPDNFLSNQFFELMALGAGTASHPET 693
+P+ + L L K + S+ P N S E +GT P+T
Sbjct: 658 EPAFKTTLNSL-STKARTGSEIPINTKSPVTTE----SSGTTESPDT 699
>CE24840 [IOVE] KOG1047 Bifunctional leukotriene A4 hydrolase/aminopeptidase
LTA4H
Length = 609
Score = 90.1 bits (222), Expect = 1e-17
Identities = 111/461 (24%), Positives = 181/461 (39%), Gaps = 74/461 (16%)
Query: 16 NHYEIELSELDAEHNSFIGSVRIIMSTVNANDMISLNMRDIEIVSAVVELKEGSVSLGMK 75
+HY ++ ++D E G V I + + I L+ RD+ + S + L G
Sbjct: 21 SHYALKW-KVDFEKKHIAGDVSITLDVKQDTERIVLDTRDLSVQSVALNLNGEPKKAG-- 77
Query: 76 DHSFDLE-NDVVSLKF---PESI-SDDEFVLKIDYKGMIQTNMSGFYRSDYTDFVTGENK 130
F LE N + K ES+ S D VL+I Y+ F ++ T T
Sbjct: 78 ---FTLEDNQALGQKLVITTESLKSGDRPVLEIKYESSNNAAALQFLTAEQT---TDRVA 131
Query: 131 VMFSTQFEATDARRAFPCFDEPSLKATFDICIIAHEKYTVL------ANMPLKCTKKLTE 184
+Q +A +AR PC D PS+K+T++ + T L + P +C K+
Sbjct: 132 PYLFSQCQAINARSIVPCMDTPSVKSTYEAEVCVPIGLTCLMSAIGQGSTPSECGKRTI- 190
Query: 185 SDQISYRFHTTPLMSTYLVAWAVGEYDYIESETEKSIYPTIENYNTQDGTSSGCGKLPVK 244
+ F + +YL+A VG + E S C
Sbjct: 191 -----FSFKQPVSIPSYLLAIVVGHLERKE-------------------ISERCA----- 221
Query: 245 VYTAKGKAQQGKFALDVAKRVIDFFSESFEIPYPLPKLDLLCVE-TYSHNAMENFSLITF 303
V+ +A+ + ++++ +E PY + DL+ + T+ MEN L
Sbjct: 222 VWAEPSQAEASFYEFAETEKILKV-AEDVAGPYVWGRYDLVVLPATFPFGGMENPCLTFI 280
Query: 304 RPSALLYDGNLDEPDAAALQKIAYVVSHEIAHQWFGNLVTMKWWDELWLNEGFATWIGYL 363
P+ L D +L V++HEI+H W GNLVT W+ WLNEGF ++
Sbjct: 281 TPTLLAGDRSL-----------VNVIAHEISHSWTGNLVTNFSWEHFWLNEGFTVFLERK 329
Query: 364 AVEKFFPDWD--VPSMIMLQSHEVALELDSLKESHPIKVAVRNA--KDIDQVFDSISYLK 419
K + + + S + V D H V+N D D F S+ Y K
Sbjct: 330 IHGKMYGELERQFESESGYEEALVRTVNDVFGPDHEYTKLVQNLGNADPDDAFSSVPYEK 389
Query: 420 GCSILEMVSGYLGQ----ELFLKGVALYLKRNKFSNATMED 456
G ++L + LG E FL+ Y+++ + + E+
Sbjct: 390 GSALLFTIEQALGDNSRFEQFLRD---YIQKYAYKTVSTEE 427
>At1g63770 [EO] KOG1046 Puromycin-sensitive aminopeptidase and related
aminopeptidases
Length = 964
Score = 83.2 bits (204), Expect = 2e-15
Identities = 113/491 (23%), Positives = 201/491 (40%), Gaps = 71/491 (14%)
Query: 20 IELSELDAEHNSFIGS-VRIIMSTVNANDMISLNMRDIEIVSAVVE---LKEGSVSLGMK 75
++LS E + + S +++ ++ + L+ D++++S VE LKEG
Sbjct: 99 VDLSFSLGEEKTIVSSKIKVSPRVKGSSAALVLDGHDLKLLSVKVEGKLLKEG------- 151
Query: 76 DHSFDLENDVVSLKFPESISDDEFVLKIDYK--GMIQTNMSGFYRSDYTDFVTGENKVMF 133
D + D L P +++ FVL+ID + T++ G Y+S F
Sbjct: 152 ----DYQLDSRHLTLPSLPAEESFVLEIDTEIYPHKNTSLEGLYKSSGN----------F 197
Query: 134 STQFEATDARRAFPCFDEPSLKATFDICIIAHEK--YTVLANMPLKCTKKLTESDQISYR 191
TQ EA R+ D P + A + C + +K Y VL + ++ E + Y
Sbjct: 198 CTQCEAEGFRKITFYQDRPDIMAKYT-CRVEGDKTLYPVLLSNGNLISQGDIEGGR-HYA 255
Query: 192 FHTTPLMST-YLVAWAVGEYDYIESETEKSIYPTIENYNTQDGTSSGCGKLPVKVYTAKG 250
P YL A G+ + + + T+ G ++ +K++T
Sbjct: 256 LWEDPFKKPCYLFALVAGQ-----------LVSRDDTFTTRSGR-----QVSLKIWTPAE 299
Query: 251 KAQQGKFALDVAKRVIDFFSESFEIPYPLPKLDLLCVETYSHNAMENFSLITFRPSALLY 310
+ A+ K + + + F + Y L +++ V ++ AMEN SL F +L
Sbjct: 300 DLPKTAHAMYSLKAAMKWDEDVFGLEYDLDLFNIVAVPDFNMGAMENKSLNIFNSKLVLA 359
Query: 311 DGNL-DEPDAAALQKIAYVVSHEIAHQWFGNLVTMKWWDELWLNEG--------FATWIG 361
+ D AA I V+ HE H W GN VT + W +L L EG F++ +G
Sbjct: 360 SPETATDADYAA---ILGVIGHEYFHNWTGNRVTCRDWFQLSLKEGLTVFRDQEFSSDMG 416
Query: 362 YLAVEKFFPDWDVPSMIMLQSHEVALELDSLKESHPIK--VAVRNAKDIDQVFDSISYLK 419
V++ DV + + Q + D+ +HP++ ++ + + +S+
Sbjct: 417 SRTVKRIA---DVSKLRIYQFPQ-----DAGPMAHPVRPHSYIKVYEKVWLFTNSVLLYA 468
Query: 420 GCSILEMVSGYLGQELFLKGVALYLKRNKFSNATMEDLFNCIGEVADIEVLERCKNWILT 479
G ++ M LG + F KG+ LY +R+ T ED F + + + + W
Sbjct: 469 GAEVVRMYKTLLGTQGFRKGIDLYFERHDEQAVTCEDFFAAMRDANNAD-FANFLQWYSQ 527
Query: 480 IGYPLVTVTES 490
G P+V V S
Sbjct: 528 AGTPVVKVVSS 538
>Hs20537652 [IOVE] KOG1047 Bifunctional leukotriene A4 hydrolase/aminopeptidase
LTA4H
Length = 650
Score = 75.1 bits (183), Expect = 4e-13
Identities = 86/352 (24%), Positives = 134/352 (37%), Gaps = 73/352 (20%)
Query: 127 GENKVMFSTQFEATDARRAFPCFDEPSLKATFDICIIAHEKYTVLANMPLKCTKKLTESD 186
G+ K TQ +A R FPCFD P++K + I + +T + + +
Sbjct: 160 GKKKPFVYTQGQAVLNRAFFPCFDTPAVKYKYSALIEVPDGFTAVMS-----ASTWEKRG 214
Query: 187 QISYRFHTTPLMSTYLVAWAVGEYDYIESETEKSIYPTIENYNTQDGTSSGCGKLPVKVY 246
+ F + +YL+A A+G D + +E G S P +
Sbjct: 215 PNKFFFQMCQPIPSYLIALAIG--DLVSAEV---------------GPRSRVWAEPCLID 257
Query: 247 TAKGKAQQGKFALDVAKRVIDFF---SESFEIPYPLPKLDLLCVE-TYSHNAMENFSLIT 302
AK + VI+ F E PY + DLL + ++ MEN L
Sbjct: 258 AAK----------EEYNGVIEEFLATGEKLFGPYVWGRYDLLFMPPSFPFGGMENPCLTF 307
Query: 303 FRPSALLYDGNLDEPDAAALQKIAYVVSHEIAHQWFGNLVTMKWWDELWLNEGFATW--- 359
P L D +L A V+ HEI+H WFGNLVT W E WLNEGF +
Sbjct: 308 VTPCLLAGDRSL-----------ADVIIHEISHSWFGNLVTNANWGEFWLNEGFTMYAQR 356
Query: 360 --------IGYLAVEKFFPDWDVPSMIMLQSHEVALELDSLKESHP---IKVAVRNAKDI 408
Y +E +L+ H +D E +P ++V + D
Sbjct: 357 RISTILFGAAYTCLEA------ATGRALLRQH-----MDITGEENPLNKLRVKIEPGVDP 405
Query: 409 DQVFDSISYLKGCSILEMVSGYLG-QELFLKGVALYLKRNKFSNATMEDLFN 459
D ++ Y KG + ++ +G Q+ F + Y+ KF + +D +
Sbjct: 406 DDTYNETPYEKGFCFVSYLAHLVGDQDQFDSFLKAYVHEFKFRSILADDFLD 457
>Hs13443031 [IOVE] KOG1047 Bifunctional leukotriene A4 hydrolase/aminopeptidase
LTA4H
Length = 657
Score = 73.9 bits (180), Expect = 1e-12
Identities = 86/352 (24%), Positives = 134/352 (37%), Gaps = 74/352 (21%)
Query: 127 GENKVMFSTQFEATDARRAFPCFDEPSLKATFDICIIAHEKYTVLANMPLKCTKKLTESD 186
G+ K TQ +A R FPCFD P++K + I + +T + + + +
Sbjct: 168 GKKKPFVYTQGQAVLNRAFFPCFDTPAVKYKYSALIEVPDGFTAVMS-----ARPGEKRG 222
Query: 187 QISYRFHTTPLMSTYLVAWAVGEYDYIESETEKSIYPTIENYNTQDGTSSGCGKLPVKVY 246
+ F + +YL+A A+G D + +E G S P +
Sbjct: 223 PNKFFFQMCQPIPSYLIALAIG--DLVSAEV---------------GPRSRVWAEPCLID 265
Query: 247 TAKGKAQQGKFALDVAKRVIDFF---SESFEIPYPLPKLDLLCVE-TYSHNAMENFSLIT 302
AK VI+ F E PY + DLL + ++ MEN L
Sbjct: 266 AAKEY-----------NGVIEEFLATGEKLFGPYVWGRYDLLFMPPSFPFGGMENPCLTF 314
Query: 303 FRPSALLYDGNLDEPDAAALQKIAYVVSHEIAHQWFGNLVTMKWWDELWLNEGFATW--- 359
P L D +L A V+ HEI+H WFGNLVT W E WLNEGF +
Sbjct: 315 VTPCLLAGDRSL-----------ADVIIHEISHSWFGNLVTNANWGEFWLNEGFTMYAQR 363
Query: 360 --------IGYLAVEKFFPDWDVPSMIMLQSHEVALELDSLKESHP---IKVAVRNAKDI 408
Y +E +L+ H +D E +P ++V + D
Sbjct: 364 RISTILFGAAYTCLEA------ATGRALLRQH-----MDITGEENPLNKLRVKIEPGVDP 412
Query: 409 DQVFDSISYLKGCSILEMVSGYLG-QELFLKGVALYLKRNKFSNATMEDLFN 459
D ++ Y KG + ++ +G Q+ F + Y+ KF + +D +
Sbjct: 413 DDTYNETPYEKGFCFVSYLAHLVGDQDQFDSFLKAYVHEFKFRSILADDFLD 464
>At5g13520 [IOVE] KOG1047 Bifunctional leukotriene A4 hydrolase/aminopeptidase
LTA4H
Length = 616
Score = 68.9 bits (167), Expect = 3e-11
Identities = 87/410 (21%), Positives = 159/410 (38%), Gaps = 65/410 (15%)
Query: 135 TQFEATDARRAFPCFDEPSLKATFDICI-IAHEKYTVLANMPLKCTKKLTE--------- 184
TQ +A AR FPC D P+ + +D+ + I + V++ ++ + E
Sbjct: 127 TQCQAIHARSIFPCQDTPAARIRYDVVMNIPNSLSAVMSARHVRRRLAVPEEAKHLEAGS 186
Query: 185 --------SDQISYRFHTTPLMSTYLVAWAVGEYDYIESETEKSIYPTIENYNTQDGTSS 236
D++ F + YL A+AVGE + E +Y T+
Sbjct: 187 LGSSLWCGEDRVVEEFAMEQPIPPYLFAFAVGELGFREVGPRTRVY-------TESAAIE 239
Query: 237 GCGKLPVKVYTAKGKAQQGKFALDVAKRVIDFFSESFEIPYPLPKLDLLCVETYSHNAME 296
++ + +QG+ K D+ E F++ L+ ++ + ME
Sbjct: 240 VLDAAALEFAGTEDMIKQGE------KLFGDYEWERFDL--------LVLPPSFPYGGME 285
Query: 297 NFSLITFRPSALLYDGNLDEPDAAALQKIAYVVSHEIAHQWFGNLVTMKWWDELWLNEGF 356
N ++ P+ + + DA Q VV+HE+AH W GNL+T + WLNEGF
Sbjct: 286 NPRMVFLTPTVI-------KGDATGAQ----VVAHELAHSWTGNLITNINNEHFWLNEGF 334
Query: 357 ATWIGYLAVEKFFPDWDVPSM-IMLQSHEVALELDSLKESHPIKVA--VRNAKDIDQVFD 413
T+ VE D+ ++ I + + E++ K++ + D D V+
Sbjct: 335 TTYAERRIVE-VVQGADIATLNIGIGWRGLTDEMERFKDNLECTKLWNKQEGVDPDDVYS 393
Query: 414 SISYLKGCSILEMVSGYLGQELFLKGVALYLKRNKFSNATMEDLFNCI-GEVADIEVLER 472
+ Y KG + + +G+ F + + Y+ KF + + + IE
Sbjct: 394 QVPYEKGFQFVLRIERQIGRTAFDEFLKKYIATFKFKSIDTNTFLEFLKANIPGIEKEIN 453
Query: 473 CKNWILTIGY------PLVTVTESEIGLSLTQNRFLSTGTCKPDEDVTKW 516
+ W +G P+ T+ I L+ + G ++DV +W
Sbjct: 454 LQLWTEGVGIPEDAYEPVSTIYTKIISLA----KEFKEGKMPSEDDVAEW 499
>CE28160 [IOVE] KOG1047 Bifunctional leukotriene A4 hydrolase/aminopeptidase
LTA4H
Length = 625
Score = 67.0 bits (162), Expect = 1e-10
Identities = 74/325 (22%), Positives = 130/325 (39%), Gaps = 60/325 (18%)
Query: 135 TQFEATDARRAFPCFDEPSLKATFDICIIAHEKYTVLANMPLKCTKKLTESDQISYRFHT 194
+Q +A AR PC D PS+K+T++ + T L + + +K + D ++ +
Sbjct: 140 SQCQAIHARSIVPCMDTPSVKSTYEAEVTVPTGMTCLMSAIGQGSKG--DDDTTTFFYKQ 197
Query: 195 TPLMSTYLVAWAVGEYDYIESETEKSIYPTIENYNTQDGTSSGCGKLPVKVYTAKGKAQQ 254
+ +YL+A VG + + +++ P V A + +
Sbjct: 198 PVAIPSYLIAIVVGCLEKRDISDRCAVWAE-----------------PSVVDKAHWEFAE 240
Query: 255 GKFALDVAKRVIDFFSESFEIPYPLPKLDLLCVE-TYSHNAMENFSLITFRPSALLYDGN 313
+ L A+ + Y + D++C+ ++ MEN L P+ + D +
Sbjct: 241 TEDILASAEEIAG--------KYIWGRYDMVCLPPSFPFGGMENPCLTFLTPTLIAGDRS 292
Query: 314 LDEPDAAALQKIAYVVSHEIAHQWFGNLVTMKWWDELWLNEGFATWI-----GYLAVEKF 368
L V++HEIAH W GNLVT W+ WLNEGF +I G L E +
Sbjct: 293 L-----------VSVIAHEIAHSWSGNLVTNSSWEHFWLNEGFTMFIERKICGRLVSEDY 341
Query: 369 -----FPDWDVPSMIMLQSHEVALELDSLKESHPIKVAVRNAKDIDQ--VFDSISYLKGC 421
F W + + + +H +++ ++D F + Y KG
Sbjct: 342 RQFMAFNGW--------TNSLIPAVYEQFTPTHQFTKLIQDHTNVDPDVAFSCVPYEKGS 393
Query: 422 SILEMVSGYL-GQELFLKGVALYLK 445
++L + L G E+F + YLK
Sbjct: 394 ALLFYLEQKLGGSEIFEAYLKDYLK 418
>SPCC1322.05c [IOVE] KOG1047 Bifunctional leukotriene A4 hydrolase/aminopeptidase
LTA4H
Length = 612
Score = 64.7 bits (156), Expect = 6e-10
Identities = 95/461 (20%), Positives = 180/461 (38%), Gaps = 66/461 (14%)
Query: 14 RANHYEIELSELD------AEHNSFIGSVRIIMSTVNANDMISLNMRDIEIVSAVVELKE 67
++N++++ +S+LD + G V ++ + + +S + D ++ +E+K
Sbjct: 10 QSNYHDVSISKLDWHARIDFDQELLHGKVSFVIQSARVSQALSHIILD----TSYLEIKN 65
Query: 68 GSVSLGMKDHSFDLENDVVS-----LKFPESISDDEFVLKIDYKGMIQTNMSGFYRSDYT 122
+++ D + + E S +L I Y F + + T
Sbjct: 66 VTINDIPTPFRVDKRRGFLGSALHIVPADEIPSSKSCILTILYSTTKDCTALQFLKPEQT 125
Query: 123 DFVTGENKVMFSTQFEATDARRAFPCFDEPSLKA--TFDICIIAHEKYTVLANMPLKCTK 180
+ G+ +FS + +A AR PC D PS+K TF I K V+A+ + C
Sbjct: 126 --IGGKFPYVFS-ECQAIHARSFIPCQDTPSVKVPCTFKI----RSKLPVIAS-GIPCGT 177
Query: 181 KLTESDQISYRFHTTPLMSTYLVAWAVGEYDYIESETEKSIYPTIENYNTQDGTSSGCGK 240
+ + Y F + +YL G+ +T G S
Sbjct: 178 ANFCNGSLEYLFEQKNPIPSYLFCILSGDLA-----------------STNIGPRSS--- 217
Query: 241 LPVKVYTAKGKAQQGKFALDVAKRVIDFFSESFEIPYPLPKLDLLCVE-TYSHNAMENFS 299
VYT G K+ + +E +PY + D + + ++ + MEN
Sbjct: 218 ----VYTEPGNLLACKYEFEHDMENFMEAAEQLTLPYCWTRYDFVILPPSFPYGGMEN-- 271
Query: 300 LITFRPSALLYDGNLDEPDAAALQKIAYVVSHEIAHQWFGNLVTMKWWDELWLNEGFATW 359
P+A L D + + V++HE+AH W GNLVT + W WLNEG +
Sbjct: 272 -----PNATFATPTLIAGDRSNVN----VIAHELAHSWSGNLVTNESWQCFWLNEGMTVF 322
Query: 360 IGYLAVEKFF--PDWDVPSMIMLQSHEVALELDSLKESHPIKVAVRNAKDIDQVFDSISY 417
+ + + + P ++I E +++L + + +D D F ++ Y
Sbjct: 323 LERKILGRLYGEPTRQFEAIIGWGELEESVKLLGEDSEYTKLIQNLEGRDPDDAFSTVPY 382
Query: 418 LKGCSILEMVSGYL-GQELFLKGVALYLKRNKFSNATMEDL 457
KG + L + + G +F + Y + KF+ +T+ ++
Sbjct: 383 EKGSNFLYEIERVIGGPSVFEPFLPFYFR--KFAKSTVNEV 421
>CE19614 [K] KOG1932 TATA binding protein associated factor
Length = 1086
Score = 62.4 bits (150), Expect = 3e-09
Identities = 55/225 (24%), Positives = 100/225 (44%), Gaps = 27/225 (12%)
Query: 142 ARRAFPCFDEPSLKATFDICIIAHEKYTVLANMPLKCTKKLTESDQISYRFHTTPLMSTY 201
AR C DEP A +++ +A+ L+ ++++E+ +I Y+FH T S
Sbjct: 227 AREWTVCLDEPDQLALWELTFELEPHLVPVASGELEEKREVSENGKIRYKFHQTVPTSAC 286
Query: 202 LVAWAVGEYDYIESETEKSIYPTIENYNTQDGTSSGCGKLPVKVYTAKGKAQQGKFALDV 261
+ WA+G + +E E PTI ++ G P +T LD
Sbjct: 287 NIGWAIGRFK-LEPHPES---PTIYTFSLP-------GLEPFVNHTT--------MYLD- 326
Query: 262 AKRVIDFFSESFEIPYPLPKLDLLCVETYSHNAMENFSLITFRPSALLYDGNLDEPDAAA 321
++++F E +P P L ++ V+ + ++ +S + P+A+LY + + A
Sbjct: 327 --KMVEFLEEKLSCRFPYPTLKVVFVDQCTEE-IQVYSSLLIVPTAMLYHKKIIDVVQEA 383
Query: 322 LQKIAYVVSHEIAHQWFGNLVTMKWWDELWLNEGFATWIGYLAVE 366
QK+ + IA Q+FG L++ W W+ A ++ L VE
Sbjct: 384 RQKLIF----SIALQFFGCLISPAQWWHWWIPVSIARFLTSLYVE 424
>CE00646 [EO] KOG1046 Puromycin-sensitive aminopeptidase and related
aminopeptidases
Length = 781
Score = 57.8 bits (138), Expect = 7e-08
Identities = 92/468 (19%), Positives = 180/468 (37%), Gaps = 80/468 (17%)
Query: 10 PTDFRANHYEIELSELDAEHNSFIGSVRIIMSTVNANDMISLNMRDIEIVSA-----VVE 64
P+ F+ HY + ++ D G +++ ST + ISL+ I + VV
Sbjct: 172 PSKFQPIHYVLNITIRDVRKPVLEGHMQLFASTKDQVQAISLHSVKIHNLENRDRIHVVN 231
Query: 65 LKEGSVSLGMKDHSFDLENDVVSLKFPESISDDEFVLKIDYKGMIQTNMSGFYRSDYTDF 124
G + H D D++ L+ +SIS L++D G I + +
Sbjct: 232 CNTGETICVSRVHQID---DLIHLELAQSISSG-VNLRVDIDGFISADSGPHV---FKQI 284
Query: 125 VTGENKV--MFSTQFEATDARRAFPCFDEPSLKATFDICIIAHEKYTVLANMPLKCTKKL 182
T + +V M + FE T AR FP FD + K+TF++C+ + +AN +
Sbjct: 285 PTAKWRVPQMIGSVFEPTSARHVFPSFDLHNQKSTFNLCLNHGPSMSAIANSLINPN--- 341
Query: 183 TESDQISYRFHTTPLMSTYLVAWAVGEYDYIESETEKSIYPTIENYNTQDGTSSGCGKLP 242
+ IS T PL++ L ++ E ++ YNT + ++
Sbjct: 342 VSTSGISCFEKTVPLIAQQL--------SFVAFEKTNPLF-----YNTTTMDGAYLPEID 388
Query: 243 VKVYTAKGKAQQGKFALDVAKRVIDFFSESFEIPYPLPKLDLLCVETYS-HNAMENFSLI 301
+ +Q ++ +V+ S+ YPL +L+++ + H+A+ +I
Sbjct: 389 MIFNLNAKNFKQYEWIHSEVSKVMALMSKWSGFSYPLTRLEIVVAPVQAGHSAL---GVI 445
Query: 302 TFRPSALLYDGNLDEPDAAALQKIAYVVSHEIAHQWFGNLVTMKWWDELWLNEGFATWIG 361
T A+ Y + + + E+ QW +VT +
Sbjct: 446 TLPAQAIAYQKHTSTHE---------TLIKEVIGQWMEGVVTTE---------------- 480
Query: 362 YLAVEKFFPDWDVPSMIMLQSHEVALELDSLKESHPIKVAVRNAKDIDQVFDSISYLKG- 420
+ EK ++I ++ EL +K++ ++V+ +++++ DS+ L+
Sbjct: 481 HTCFEK--------ALIAYVEWKINEELQIVKKTRKMEVSKIRPRNLNETADSVRVLRQI 532
Query: 421 -------CS-----ILEMVSGYLGQELFLKGVALYLKRNKFSNATMED 456
CS + + GQE + + + + FS AT+ D
Sbjct: 533 KSQSSNLCSPRFVEVFYTLDETYGQETVIGMIRVIFDKFAFSTATISD 580
>Hs17472410 [EO] KOG1046 Puromycin-sensitive aminopeptidase and related
aminopeptidases
Length = 365
Score = 55.8 bits (133), Expect = 3e-07
Identities = 29/86 (33%), Positives = 51/86 (58%), Gaps = 1/86 (1%)
Query: 130 KVMFSTQFEATDARRAFPCFDEPSLKATFDICIIAHEKYTVLANMPLKCTKKLTESDQIS 189
K + +T E TDAR+ FPCFD+P+ KAT+ I + ++Y L++MP+ ++ +
Sbjct: 240 KSIAATDHEPTDARKFFPCFDKPNKKATYTISVTHPKEYEALSHMPV-AKEESVDDKWNQ 298
Query: 190 YRFHTTPLMSTYLVAWAVGEYDYIES 215
F + MS YLV +AV ++ +++
Sbjct: 299 TTFKKSVPMSMYLVCFAVHQFHTVKT 324
>Hs20070296 [IOVE] KOG1047 Bifunctional leukotriene A4 hydrolase/aminopeptidase
LTA4H
Length = 494
Score = 55.5 bits (132), Expect = 4e-07
Identities = 50/189 (26%), Positives = 82/189 (42%), Gaps = 27/189 (14%)
Query: 329 VSHEIAHQWFGNLVTMKWWDELWLNEGFATWIGYLAVEKFFPDWDVPSMIMLQSHEVALE 388
V HE+AH WFGN VT W+E+WL+EG AT+ A + + + L E A
Sbjct: 120 VIHEVAHSWFGNAVTNATWEEMWLSEGLATY----AQRRITTETYGAAFTCL---ETAFR 172
Query: 389 LDSLK-------ESHPI---KVAVRNAKDIDQVFDSISYLKGCSILEMVSGYLGQ-ELFL 437
LD+L E P+ +V + + + + +Y KG + +S G + F
Sbjct: 173 LDALHRQMKLLGEDSPVSKLQVKLEPGVNPSHLMNLFTYEKGYCFVYYLSQLCGDPQRFD 232
Query: 438 KGVALYLKRNKFSNATMEDLFNCI--------GEVADIEVLERCKNWILTIGYPLVTVTE 489
+ Y+++ KF++ +DL + + D + W+ G PL
Sbjct: 233 DFLRAYVEKYKFTSVVAQDLLDSFLSFFPELKEQSVDCRAGLEFERWLNATGPPLAEPDL 292
Query: 490 SEIGLSLTQ 498
S+ G SLT+
Sbjct: 293 SQ-GSSLTR 300
>CE25399 [EO] KOG1046 Puromycin-sensitive aminopeptidase and related
aminopeptidases
Length = 735
Score = 54.3 bits (129), Expect = 8e-07
Identities = 115/564 (20%), Positives = 211/564 (37%), Gaps = 90/564 (15%)
Query: 69 SVSLGMKDHSFDLENDVVSLKFPESISDDEFVLKID---------------YKGMIQTNM 113
+VSL M H ++ F ++DD L +D YKG+I + +
Sbjct: 103 NVSLVMNGHELEI--------FNVQLTDDSMELSVDQPVLFPGRYTLTIHRYKGLIGSAI 154
Query: 114 SGFYR---SDYTDFVTGENKVMFSTQFEATDARRAFPCFDEPSLKATFDICIIAHEKYTV 170
+YR V +F + A FP + + K TF I ++
Sbjct: 155 --YYRYPPPPPPPLVDAGEHAVFGSNLFPNRAPAVFPSYLASTEKVTFSITMVHPVGTLA 212
Query: 171 LANMPLK-CTKKLTESDQISYRFHTTPLMSTYLVAWAVGEYDYIESETEKSIYPTIENYN 229
L + + +K+ E+ Q++ F TTP ++ ++ + + ++Y E+ + +YN
Sbjct: 213 LTSGSNEGAPRKIDENWQMT-TFSTTPSITPSMLCFLLLPHEYTHIESTYTGVNISVHYN 271
Query: 230 TQDGTSSGCGKLPVKVYTAKGKAQQGKFALDVAKRVIDFFSESFEIPYPLPKLDLLCVET 289
+ + +Q K L A +V+ + F P+PK+D++ +
Sbjct: 272 R-----------------FRVQKEQTKHLLHTATQVLALLKDIFSSLIPVPKIDIITMNE 314
Query: 290 YSHNAMENFSLITFRPSALLYDGNLDEPDAAALQKIAYVVSHEIAHQWFGNLVTMKWWDE 349
S A S ++ + D A K +++ +A QW G + E
Sbjct: 315 VSSTACFG--------SIVVSEVQFFSADYANQVK---MLATWLAKQWIGGYAAISEGSE 363
Query: 350 LWLNEGFATWIGYLAVEKF----FPDWDVPSMIMLQSHEVALELDSLK-ESHPIKVAVRN 404
L L E +I +++ F + I L S + D+LK + HP +
Sbjct: 364 LCLQEDLVAFIADKVIKRMTNDEFTRLGHLAKIYL-SETIFTAGDTLKLDEHPNEF---- 418
Query: 405 AKDIDQVFDSISYLKGCSILEMVSGYLGQELFLKGVALYL---KRNKFSNATMEDLFNCI 461
++F+ LKG ++LE + +G++ + + + K+ +S+ T+ L N
Sbjct: 419 -----EIFEKCG-LKGVAMLESIESLIGEKSMISKINEMIYNSKKGSYSSRTLYGLLNST 472
Query: 462 GEVADIEVLERCKNWILTIGYPLVTVTESEIGLSLTQNRFLSTGTCKPD----EDVTKWW 517
+ DI V + W G P + V + +TQN S T K E + W
Sbjct: 473 VD-EDIYVSQLLHYWHEHGGLPYMNVDRLANSIKITQNG--SNMTVKNGAGTWERMPLWP 529
Query: 518 VPLMPLQGDYKVDF---SGKTTELPKTQFNHFNANSFGFYRVKYDSD---HLFQQQLQNL 571
+PL + + G + N +YRV YD D + +N
Sbjct: 530 LPLKFTEFKLPIQIMVSHGIHLSPIRDGLIFSNLGFTNYYRVNYDIDTWREIKTVLTENA 589
Query: 572 DKLSSRGKMGLISDVEVTECVKNL 595
+ R + L+SD +K+L
Sbjct: 590 TSYTLRERFQLVSDFCYFYSIKSL 613
Database: KOG eukaryal database 04/03
Posted date: Apr 14, 2003 1:07 PM
Number of letters in database: 30,389,216
Number of sequences in database: 60,738
Lambda K H
0.320 0.136 0.396
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 49,943,880
Number of Sequences: 60738
Number of extensions: 2134379
Number of successful extensions: 5641
Number of sequences better than 1.0e-05: 60
Number of HSP's better than 0.0 without gapping: 45
Number of HSP's successfully gapped in prelim test: 15
Number of HSP's that attempted gapping in prelim test: 5319
Number of HSP's gapped (non-prelim): 96
length of query: 877
length of database: 30,389,216
effective HSP length: 115
effective length of query: 762
effective length of database: 23,404,346
effective search space: 17834111652
effective search space used: 17834111652
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)