ORF STATUS Function Best COG Functional category Pathways and functional systems
r_klactIV3336 good R KOG2048 General function prediction only WD40 repeat protein
Only best alignment is shown:
BLASTP 2.2.3 [May-13-2002]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= r_klactIV3336 1134277 1132070 -736
(736 letters)
Database: KOG eukaryal database 04/03
60,738 sequences; 30,389,216 total letters
Searching..................................................done
Color Key for Alignment Scores: 
Score E
Sequences producing significant alignments: (bits) Value
YDR324c [R] KOG2048 WD40 repeat protein 840 0.0
SPBC19F5.02c [R] KOG2048 WD40 repeat protein 468 e-131
Hs14249536 [R] KOG2048 WD40 repeat protein 167 5e-41
7294173 [R] KOG2048 WD40 repeat protein 134 4e-31
At1g27470 [R] KOG2048 WD40 repeat protein 105 3e-22
At4g07410 [R] KOG2048 WD40 repeat protein 91 5e-18
CE19973 [R] KOG2048 WD40 repeat protein 74 8e-13
Hs13376840 [R] KOG4155 FOG: WD40 repeat 64 6e-10
SPAC227.12 [A] KOG0272 U4/U6 small nuclear ribonucleoprotein Prp... 59 3e-08
Hs8922428 [S] KOG0271 Notchless-like WD40 repeat-containing protein 56 2e-07
At5g13840 [DO] KOG0305 Anaphase promoting complex Cdc20 Cdh1 and... 52 3e-06
At1g52730 [I] KOG0278 Serine/threonine kinase receptor-associate... 52 3e-06
7290231 [R] KOG4155 FOG: WD40 repeat 52 3e-06
CE06574 [R] KOG0266 WD40 repeat-containing protein 52 3e-06
CE17294 [S] KOG0271 Notchless-like WD40 repeat-containing protein 51 6e-06
At3g15610 [I] KOG0278 Serine/threonine kinase receptor-associate... 51 6e-06
Hs13129110 [A] KOG0284 Polyadenylation factor I complex subunit ... 50 1e-05
7296695 [A] KOG0284 Polyadenylation factor I complex subunit PFS2 50 1e-05
>YDR324c [R] KOG2048 WD40 repeat protein
Length = 776
Score = 840 bits (2171), Expect = 0.0
Identities = 421/750 (56%), Positives = 548/750 (72%), Gaps = 21/750 (2%)
Query: 6 KKQVVHRSRFVQFTPGNITALAFSHKST-DKAAPQELRLAIGRSNGNIEIWNPRDDWVQE 64
++ +VHR RFV FTP IT+LAFSHKS +K P +LRLAIGRSNGNIEIWNPR++W QE
Sbjct: 29 ERMIVHRCRFVDFTPATITSLAFSHKSNINKLTPSDLRLAIGRSNGNIEIWNPRNNWFQE 88
Query: 65 FVILGGEGRSIEGLSWCSIRGEPLRLFSIGGSTVVTEWDLTTGLPLVNYDCNSGVIWSIA 124
VI GG+ RSIEGL W ++ GE LRLFSIGGSTVVTEWDL TGLPL NYDCNSGVIWSI+
Sbjct: 89 MVIEGGKDRSIEGLCWSNVNGESLRLFSIGGSTVVTEWDLATGLPLRNYDCNSGVIWSIS 148
Query: 125 MSNDMNKLAVGCDNGSVVLINISGGKGVLEHESILTRQESRVLSLTWTANDESLVAGCSD 184
+++ +KL+VGCDNG+VVLI+ISGG GVLEH++IL RQE+RVL+L W D+ ++ GCSD
Sbjct: 149 INDSQDKLSVGCDNGTVVLIDISGGPGVLEHDTILMRQEARVLTLAWK-KDDFVIGGCSD 207
Query: 185 GRIRIWYTKEQDENKGRLLHTMKVDKSKKESTLVWSVLYLAKQNQIVSGDSTGSVKFWDL 244
GRIRIW ++ DEN GRLLHTMKVDK+KKESTLVWSV+YL + +QI SGDSTGS+KFWD
Sbjct: 208 GRIRIWSAQKNDENMGRLLHTMKVDKAKKESTLVWSVIYLPRTDQIASGDSTGSIKFWDF 267
Query: 245 NYATLTQSFKVHDADVLCLATDLDNSQLFTSGVDRKIFQFSYIDTGKSMK---WISTSNR 301
+ATL QSFK HDADVLCL TD DN+ +F++GVDRKIFQFS +T KS K W+++SNR
Sbjct: 268 QFATLNQSFKAHDADVLCLTTDTDNNYVFSAGVDRKIFQFSQ-NTNKSQKNNRWVNSSNR 326
Query: 302 LFHSNDVRSMSSYQCMGSDFLVSGGIEKSLVMCSMSSFAEGNYRKMPLVTPFHKSILVNK 361
L H ND+R++ +YQ G+DFLVSGG+EK+LV+ S++SF+ GNYRKMP V P+ K++LVNK
Sbjct: 327 LLHGNDIRAICAYQSKGADFLVSGGVEKTLVINSLTSFSNGNYRKMPTVEPYSKNVLVNK 386
Query: 362 QQRLLVMWQDNIVKIWYIGEDVNEPKNYKLVSKLVLKDEQNIQTCALSTDGQVLLVGRLN 421
+QRL+V W ++ VKIW +G D + +NYKLV KL LKD+QNI TC+LS DGQVL+VGR +
Sbjct: 387 EQRLVVSWSESTVKIWTMGTDSSTEQNYKLVCKLTLKDDQNISTCSLSPDGQVLVVGRPS 446
Query: 422 TTKVFHLQPTDNKLKVTKLDNEFLLRTGCKFAKFIDDSRLIMCSQSDEIVRIDLEEDDDE 481
TTKVFHLQP NKLKVTKLDN+ LLRT K KFID+S++++CS D++ +DLE ++DE
Sbjct: 447 TTKVFHLQPVGNKLKVTKLDNDLLLRTSTKLVKFIDNSKIVICSCEDDVFIVDLESEEDE 506
Query: 482 KTVTIELPEANSTKSSNKLSYLNAVNHLDANERYAVASRGTGALDLIDLTTNSSKALIRM 541
K +EL E STKSS K+ Y+N +NHL+ ++ AV SRG G +D++DL SK L R+
Sbjct: 507 KPQEVELLEVTSTKSSIKVPYINRINHLEVDQNIAVISRGCGVVDILDLKARISKPLARL 566
Query: 542 NNFITALCI-TPRETVVVVTSENKIYEFNL-------ESEKDQLLTDWFKANHENLPRQF 593
NNFITA+ I T R++VVV+T++NKIYEFN+ + + +LT W K N +NLP+++
Sbjct: 567 NNFITAVHINTSRKSVVVITADNKIYEFNMNLNSEAENEDSESVLTQWSKNNTDNLPKEW 626
Query: 594 TSLKERCTGIFLDEMDEHKVWFWGSNWLVNINMSLDLPVSXXXXXXXXXXXGLTISTDG- 652
+LKE C GIF D + ++WFWG+ W+ I+ +D P++ GLTI+ +
Sbjct: 627 KTLKENCVGIFSDIENSSRLWFWGATWISRIDFDVDFPINKRRKQKKRTHEGLTITDESN 686
Query: 653 -LQAXXXXXXXXXXXXXXXXXYLLKTQ----RAQDVTSKKRSDKAFFYTDKYRPLLFAGK 707
+ +L Q ++ DV + S FF+TDKY+PLLF
Sbjct: 687 FMNDEEDDEDDDIDMEISENLNVLLNQGNKIKSTDVQRNEESSGHFFFTDKYKPLLFVDL 746
Query: 708 IASDQLIIVER-PNFLISQPPAFELEKLVF 736
I+S++L I+ER P S+ AF KLVF
Sbjct: 747 ISSNELAIIERNPLTFHSKQKAFIQPKLVF 776
>SPBC19F5.02c [R] KOG2048 WD40 repeat protein
Length = 710
Score = 468 bits (1204), Expect = e-131
Identities = 267/723 (36%), Positives = 409/723 (55%), Gaps = 49/723 (6%)
Query: 10 VHRSRFVQFTPGNITALAFSHKS-TDKAAPQELRLAIGRSNGNIEIWNPRDDWVQEFVIL 68
+HR RF+ +TP ITA+AFSHKS + + P L LA+GR++GNIEIWNPR+DW + V+
Sbjct: 3 IHRCRFIDYTPSAITAMAFSHKSGQNDSMPNNLLLAVGRASGNIEIWNPRNDWCLKTVLY 62
Query: 69 GGEGRSIEGLSWCSIRGEPLRLFSIGGSTVVTEWDLTTGLPLVNYDCNSGVIWSIAMSND 128
GG RSIEG+ W S E LRLFSIG ST +TEW+L TG PLVN D N+G IWSIA+ ++
Sbjct: 63 GGVDRSIEGIVW-STGEEELRLFSIGFSTTITEWNLHTGKPLVNQDSNAGAIWSIAICDE 121
Query: 129 MNKLAVGCDNGSVVLINISGGKGVLEHESILTRQESRVLSLTWTANDESLVAGCSDGRIR 188
LAVGCD+GS VL +ISGG GV+E + +L RQ SR+LSL + D LV GC+DG I+
Sbjct: 122 TKTLAVGCDDGSCVLFDISGGPGVIEFKRVLMRQTSRILSLDFQTKDH-LVGGCADGVIK 180
Query: 189 IWYTKEQDENKGRLLHTMKVDKSKK-ESTLVWSVLYLAKQNQIVSGDSTGSVKFWDLNYA 247
+W + ++ M+VD+++K E+ L+W+V L + IVS DS+G+VKFW+ +
Sbjct: 181 VW---DLSTPNSAIISRMQVDRARKGEAALIWAVKSL-RDGTIVSADSSGAVKFWNGKFF 236
Query: 248 TLTQSFKVHDADVLCLATDLDNSQLFTSGVDRKIFQFSYIDTGKSMKWISTSNRLFHSND 307
TL+QSFK+H AD LCL + +F+SG+DRK Q+S G +W+S S R FHS+D
Sbjct: 237 TLSQSFKLHLADALCLGVSANGDMVFSSGIDRKTIQYS--REGGKREWVSNSFRRFHSHD 294
Query: 308 VRSMSSYQCMGSDFLVSGGIEKSLVMCSMSSFAEGNYRKMPLVTPFHKSILVNKQQRLLV 367
VR M+ ++C D L+SGG++ L + + F N+R + V P + V + RL +
Sbjct: 295 VRCMAVFECKSLDVLISGGMDMMLAVIPVRQFNRKNHRMISAV-PQRPRMAVAPKARLFM 353
Query: 368 MWQDNIVKIWYIGEDVNEPKNYKLVSKLVLKDEQNIQTCALSTDGQVLLVGRLNTTKVFH 427
+W D+ V +W IG Y+ + K+VL DE+NI A+S DG+++ + + TK++
Sbjct: 354 LWNDHEVLLWRIGS-----PGYRFLLKIVLADEENISHAAISPDGELIAISSVLRTKLYQ 408
Query: 428 LQPTDNKLKVTKLDNEFLLRTGCKFAKF-IDDSRLIMCSQSDEIVRIDLEEDDDEKTVTI 486
LQ +D +KV +++ FL G F +D ++LI+ S EI I+L D +
Sbjct: 409 LQYSDENVKVETVEDSFLSNIGASLLSFTVDKNKLILVSNDSEIFLIELSRLDSRQLEVF 468
Query: 487 ELPEANSTK-----SSNKLSYLNAVNHL--DANERYAVASRGTGALDLIDLTTNSSKALI 539
EL + S K SN S + + + ++ Y + G + L+ + L
Sbjct: 469 ELSQPTSKKIAPRQRSNVSSMCDGICSIAVSSDGDYFAVADTVGNIFCYSLSNLTYSELP 528
Query: 540 RMNNFITALCITP--RETVVVVTSENKIYEFNLESEKDQLLTDWFKANHENLPRQFTSLK 597
R+N ++ A+ P R + V T+ N++YEF+++S K L++W K N N+P++F+ L
Sbjct: 529 RVNTYVRAMAFRPDVRGRLAVATAGNQVYEFDVQSRK---LSEWSKNNSTNMPKEFSQLL 585
Query: 598 ERCTGIFLDEMDEHKVWFWGSNWLVNINMSLDLPVSXXXXXXXXXXXGLTISTDGLQAXX 657
++ G F D + W W +NW+ +++L LP + + DG
Sbjct: 586 DKAFGAFFDSKHPSRFWIWSANWVSFFDLNLQLPAPRAAGKRKIE---MNATVDG----- 637
Query: 658 XXXXXXXXXXXXXXXYLLKTQRAQDVTSKKRSD-KAFFYTDKYRPLLFAGKIASDQLIIV 716
L + +++ D + F+ T KYRP+L G + + +L++V
Sbjct: 638 -----------NLNDKKLANANSNGISNYGTGDSRCFWITHKYRPMLLVGSVGNSELLVV 686
Query: 717 ERP 719
ERP
Sbjct: 687 ERP 689
>Hs14249536 [R] KOG2048 WD40 repeat protein
Length = 686
Score = 167 bits (423), Expect = 5e-41
Identities = 147/594 (24%), Positives = 266/594 (44%), Gaps = 58/594 (9%)
Query: 10 VHRSRFVQFTPGNITALAFSHKSTDKAAPQELRLAIGRSNGNIEIWNPRDDWVQEFVILG 69
VHR RF + P I +A++++S RLA+ R++G +EI+N ++ QE G
Sbjct: 6 VHRVRFFNYVPSGIRCVAYNNQSN--------RLAVSRTDGTVEIYNLSANYFQEKFFPG 57
Query: 70 GEGRSIEGLSWCSIRGEPLRLFSIGGSTVVTEWDLTTGLPLVNYDCNSGVIWSIAMSNDM 129
E R+ E L W E RLFS G + + E+DL D G IWS+A S
Sbjct: 58 HESRATEALCW----AEGQRLFSAGLNGEIMEYDLQALNIKYAMDAFGGPIWSMAASPSG 113
Query: 130 NKLAVGCDNGSVVLINISGGKGVLEHESILTRQESRVLSLTWTANDESLVAGCSDGRIRI 189
++L VGC++GSV L I+ K ++ E RQ+SR+LSL+W + + AG D
Sbjct: 114 SQLLVGCEDGSVKLFQITPDK--IQFERNFDRQKSRILSLSWHPSGTHIAAGSID----- 166
Query: 190 WYTKEQDENKGRLLHTMKVDKS----KKESTLVWSVLYLAKQNQIVSGDSTGSVKFWDLN 245
Y D G +H M VD+ K +VW V +L+ I+S DS G V+FWD
Sbjct: 167 -YISVFDVKSGSAVHKMIVDRQYMGVSKRKCIVWGVAFLS-DGTIISVDSAGKVQFWDSA 224
Query: 246 YATLTQSFKVHDADVLCLATDLDNSQLFTSGVDRKIFQFSYI---DTGKSMKWISTSNRL 302
TL +S + +ADV +A + +F F + +W+ T
Sbjct: 225 TGTLVKSHLIANADVQSIAVADQEDSFVVGTAEGTVFHFQLVPVTSNSSEKQWVRTKPFQ 284
Query: 303 FHSNDVRSMSSYQCMGSDFLVSGGIEKSLVMCSMSSFAE-GNY-RKMPLVTPFHKSILVN 360
H++D+R+++ L+SGG + LV + E NY + +T H+ ++
Sbjct: 285 HHTHDMRTVAH----SPTALISGGTDTHLVFRPLMEKVEVKNYDAALRKITFPHRCLISC 340
Query: 361 KQQRLLVMWQ-DNIVKIWYIGEDVNEPKNYKLVS---------KLVLKDEQNIQTCALST 410
++R L+++Q + +++W +G V KN + L K +NI +S
Sbjct: 341 SKKRQLLLFQFAHHLELWRLGSTVATGKNGDTLPLSKNADHLLHLKTKGPENIICSCISP 400
Query: 411 DGQVLLVGRLNTTKVFHLQPTDNKLKVTKLDN-EFLLRTGCKFAKFIDDSRLIMCSQSDE 469
G + ++ ++ L + + + ++ LR+ + D ++L + S
Sbjct: 401 CGSWIAYSTVSRFFLYRLNYEHDNISLKRVSKMPAFLRSALQILFSEDSTKLFVASNQGA 460
Query: 470 IVRIDLEEDDDEKTVTIELPEANSTKSSNKLSYLNAVNHLDANERYAVASRGTGALDLID 529
+ + L + + P++ + ++ L+ + + + AS + + + +
Sbjct: 461 LHIVQLSGGSFKHLHAFQ-PQSGTVEAMCLLA-------VSPDGNWLAASGTSAGVHVYN 512
Query: 530 LTTNSSKALIRMNNF-ITALCITPR-ETVVVVTSENKIYEFNLESEKDQLLTDW 581
+ + NF +TA+ I P +V+ S+ +++E+++ D+ TDW
Sbjct: 513 VKQLKLHCTVPAYNFPVTAMAIAPNTNNLVIAHSDQQVFEYSI---PDKQYTDW 563
>7294173 [R] KOG2048 WD40 repeat protein
Length = 696
Score = 134 bits (338), Expect = 4e-31
Identities = 151/597 (25%), Positives = 259/597 (43%), Gaps = 76/597 (12%)
Query: 7 KQVVHRSRFVQFTPGNITALAFSHKSTDKAAPQELRLAIGRSNGNIEIWNPRDDWVQEFV 66
K VH RF P I +LA+S S LA+ R+ IE+WN + V
Sbjct: 14 KHQVHNVRFYTIKPREIVSLAYSKSSKC--------LALSRATPVIELWNLEHAPYLDRV 65
Query: 67 ILGGEGRSIEGLSWCSIRGEPLRLFSIGGSTVVTEWDLTTGLPLVNYDCNSGVIWSIAMS 126
I +E ++W R LFS+ S + EWD+ + +WSI ++
Sbjct: 66 IHLPTDSHVESIAWAGNR-----LFSVDLSGKLIEWDVIKLKQRYEHSPTGNALWSIDVN 120
Query: 127 NDMNKLAVGCDNGSVVLINISGGKGVLEHESILTRQESRVLSLTWTANDESLVAGCSDGR 186
+A+G + G + +++I + + ++S+ +Q+ RVL + + LV G ++G
Sbjct: 121 PAETDIAIGSEEGHINILSIENDE--ITYKSLFNKQKGRVLCIKFDKTGTKLVTG-TEGF 177
Query: 187 IRIWYTKEQDENKGRLLHTMKVDKSKKESTLVWSVLYLAKQNQIVSGDSTGSVKFWDLNY 246
+RIW KG LHTM + + ++ +VWS+ L+ N I++GDS G V WD +
Sbjct: 178 VRIWNVL-----KGTTLHTMTLSE---KNVIVWSLQVLS-DNTIIAGDSAGFVTVWDADN 228
Query: 247 ATLTQSFKVHDADVLCLATDLDNSQLFTSGVDR---KIFQFSYI--DTGKSMKWISTSNR 301
AT S +V D +V LA + +L SG+ +IF + I + S +WI R
Sbjct: 229 ATQIDSTRVLDKNVFALAVNNKEDRLVCSGMQPPLIRIFSKTKIKREESTSERWIKFLQR 288
Query: 302 LFHSNDVRSMSSYQCMGSDFLVSGGIEKSLVMCSMSSFAEGNYRKMPLVTPFHKSILVNK 361
H + V+S+ + D + SGG + L + S + P + S+ ++K
Sbjct: 289 DAHKHYVKSL----LVIDDQIYSGGRDGILTITSSERMQAHLSQHAPFLKGSVASMAISK 344
Query: 362 QQRLLVMWQDNIVKIWYI------GEDVNEPKNYKL--------------VSKLVLKDEQ 401
+LL++ N V +W + GED +P + + +L +K+
Sbjct: 345 --KLLLLRYPNSVHLWRLGSVAPQGEDKKKPWALPVGHTEEQLLELPPQKLLQLNVKEHN 402
Query: 402 NIQTCALSTDGQVLLVGRLNTTKVFHLQ--PTDNKLKVTKLDNEFLLRTGCKFAKFIDDS 459
IQ+ A+S+D + L ++ L+ P + V L E + F K
Sbjct: 403 FIQSAAISSDANWICYSTLKELRISRLKSDPLQVERLVDDLPEELQPASHIIFTK--QGD 460
Query: 460 RLIMCSQSDEIVRIDLEEDDDEKTVTIELPEANSTKSSNKLSYLNAVNHLDANERYAVAS 519
+++ Q++ + LEED TI+L E K N +S++ +H Y VA+
Sbjct: 461 LVLLNPQNNHLSWFTLEEDLVTFKYTIDLSE----KCKNTISHVVISSH----GEYIVAA 512
Query: 520 RGTGALDLIDLTTNSSKALIRMNNF---ITALCI---TPRETVVVVTSENKIYEFNL 570
+ + L K L+ + TAL + PR VVV + ++ E++L
Sbjct: 513 SSDHIISVWKLHGKQYKHLLNLPRHRAGTTALSMHEDYPR--VVVAYANGQLVEYDL 567
>At1g27470 [R] KOG2048 WD40 repeat protein
Length = 1117
Score = 105 bits (261), Expect = 3e-22
Identities = 156/711 (21%), Positives = 270/711 (37%), Gaps = 147/711 (20%)
Query: 11 HRSRFVQFTPGNITALAFSHKSTDKAAPQELRLAIGRSNGNIEIW--NP-RDDWVQEFVI 67
+R + + P + ALA S + AA +E +G++E+W +P W + +I
Sbjct: 4 YRCSSIDWKPSPVVALATSADGSQVAAARE--------DGSLELWLVSPGASSWHCQLII 55
Query: 68 LGGEGRSIEGLSWC---SIRGEPLRLFSIGGSTVVTEWDLTTGLPLVNYDCNSGVIWSIA 124
G I L+W S RLFS ++EWDL V D IW IA
Sbjct: 56 HGDPKSRISHLAWFGTGSKGSSSARLFSSSIDGSISEWDLFDLKQKVVLDSIGFSIWQIA 115
Query: 125 M-----------------------SNDMNK----------------------LAVGCDNG 139
+ S+D + LA CD+G
Sbjct: 116 LAPISIEAESKEAKLIQNGYLSEKSDDEEESGVEDDSELDELDEKVEALDRHLAAACDDG 175
Query: 140 SVVLINISGGKGVLEHESILTRQESRVLSLTWTANDESLVAGCSDGRIRIWYTKEQDENK 199
V + IS + + S L R R LS+TW+A+ + + +G SDG IR W D N
Sbjct: 176 CVRIYYISESDKLTYYRS-LPRVTGRALSVTWSADAQRIFSGSSDGLIRCW-----DANL 229
Query: 200 GRLLHTMKVDKS---KKESTLVWSVLYLAKQNQIVSGDSTGSVKFWDLNYATLTQSFKVH 256
++ + V +WS+L L + +VSGDSTGSV+FWD + TL Q+ H
Sbjct: 230 CHEVYRITVGLGGLGNGSELCIWSLLSL-RYGVLVSGDSTGSVQFWDSQHGTLLQAHSNH 288
Query: 257 DADVLCLATDLDNSQLFTSGVDRKIFQFSY---------IDTGKSMKWISTSNRLFHSND 307
DV LA ++++F++G D ++ + + KW H++D
Sbjct: 289 KGDVNALAASPSHNRVFSAGADGQVILYKLSGGTSRSQDFKPSSAQKWDYIGCVRAHTHD 348
Query: 308 VRSMS----------------------------------SYQCMGSDFLVSGGIEKSLVM 333
+R+++ + +G L+S G + L
Sbjct: 349 IRALTVAVPISWEGSIPDRNAKVTSPKQRRKEPAGFSYHKWAHLGVPMLISAGDDAKLYA 408
Query: 334 CSMSSFAE---GNYRKMPLVTPFHKSILVNKQQRLLVMWQD----NIVKIWYIGEDVNEP 386
S+ F + + P P Q L++ QD +I++I +I D +
Sbjct: 409 YSVQEFTKFPPHDICPAPQRVPMQMVHNTVFNQTSLLLVQDSCSLDILRI-HISNDSSGR 467
Query: 387 KNYKLVSKLVLKDEQNIQTCALSTDGQVLLVGRLNTTKVFHLQP--------TDNKLKVT 438
+ K + ++ KD + I A+S G + +F L+ + N+ ++
Sbjct: 468 VSTKPLVRVKSKDARKIICSAISNTGSLFAYSDQVRPSLFELKKNKIGKNPWSANRKRLP 527
Query: 439 KLDNEFLLRTGCKFAKFIDDSRLIMCSQSDEIVRIDLEEDD--DEKTVTIELPEANSTKS 496
L + C D SRLI+ I +D+ + T E E S
Sbjct: 528 NLPFAHSMVFSC------DCSRLIIAGHDRRIYIVDVGSMELLHSFTPRQEGQEGESPPH 581
Query: 497 SNKLSYLNAVNHLDANERYAVASRGTGALDLIDLTTNSSKALI-RMNN-FITALCITPRE 554
++ L + +N+ + A G + + +L T I R++ + A PR+
Sbjct: 582 EPPITKL----YTSSNDDWLAAINCFGDIYVFNLETQRQHWFISRLDGASVAAAGFHPRD 637
Query: 555 --TVVVVTSENKIYEFNLESEKDQLLTDWFKANHENLPRQFTSLKERCTGI 603
+V+ TS N+++ ++E+ + L+ W LP+ + + G+
Sbjct: 638 NNVIVISTSSNQVFALDVEARE---LSKWSLLQTFCLPKSYQNFPGEVVGL 685
>At4g07410 [R] KOG2048 WD40 repeat protein
Length = 728
Score = 91.3 bits (225), Expect = 5e-18
Identities = 96/376 (25%), Positives = 154/376 (40%), Gaps = 85/376 (22%)
Query: 11 HRSRFVQFTPGNITALAFSHKSTDKAAPQELRLAIGRSNGNIEIWNPRDD---WVQEFVI 67
+R V + P + ALA S + AA +E +G++EIW W + I
Sbjct: 23 YRCSSVDWKPSPVVALANSSDDSQVAAARE--------DGSLEIWLVSPGAVGWHCQLTI 74
Query: 68 LGGEGRSIEGLSWC---SIRGEPLRLFSIGGSTVVTEWDLTTGLPLVNYDCNSGVIWSIA 124
G I L+WC SI RLFS ++EWDL + + IW +A
Sbjct: 75 HGDPNSRISSLAWCCSPSIGLPSGRLFSSSIDGSISEWDLFDLKQKIVLESIGISIWQMA 134
Query: 125 M---------------------SNDMNK------------------------LAVGCDNG 139
+ SND + LA CD+G
Sbjct: 135 LAPISGFSSDVEGIKNGYLSEKSNDEEEIGSEEDGSDSDEFHEKSEEEIDRILAAACDDG 194
Query: 140 SVVLINISGGKGVLEHESI--LTRQES------------RVLSLTWTANDESLVAGCSDG 185
V L IS + + + S+ ++ + S R LS+TW+ + + + +G SDG
Sbjct: 195 CVRLYRISNLEKLTYYRSLPRVSGESSFTTSVMNIIFTGRALSVTWSPDAKRIFSGSSDG 254
Query: 186 RIRIWYTKEQDENKGRLLHTMKVDKSKKESTLVWSVLYLAKQNQIVSGDSTGSVKFWDLN 245
IR W E R+ + S E VWS+L L + + +VSGDSTG+V+FWD
Sbjct: 255 LIRCWDATSCHEVY-RITAGLGGLGSSSE-ICVWSLLSL-RCSVLVSGDSTGTVQFWDSE 311
Query: 246 YATLTQSFKVHDADVLCLATDLDNSQLFTSGVDRKIFQFSY---------IDTGKSMKWI 296
+ TL ++ H DV LA ++++F++G D ++ + + S KW
Sbjct: 312 HGTLLEAHSNHKGDVNTLAAAPSHNRVFSAGADGQVILYKLSGSTNGSQDLKPSSSQKWD 371
Query: 297 STSNRLFHSNDVRSMS 312
H++D+R+++
Sbjct: 372 YIGYVKAHTHDIRALT 387
>CE19973 [R] KOG2048 WD40 repeat protein
Length = 656
Score = 73.9 bits (180), Expect = 8e-13
Identities = 87/394 (22%), Positives = 175/394 (44%), Gaps = 51/394 (12%)
Query: 200 GRLLHTMKVDK-SKKESTLVWSVLYLAKQNQIVSGDSTGSVKFWDLNYATLTQSFKVHDA 258
G++ T+K+D+ ++++ T+ WSVL++ K + + GDS G+V FW+ +L QS +
Sbjct: 147 GKVQQTLKLDRLNRRDPTIAWSVLFV-KPSLLACGDSRGTVTFWNPIDGSLIQSISCLQS 205
Query: 259 DVLCLATDLDNSQLFTSGVDRKIFQFSYIDTGKSMKWISTSNRLFHSNDVRSMSSYQCMG 318
+L + + DNS L +GVD +I + G + + R + DVRSM+ Y+
Sbjct: 206 HILAMVS-TDNSTLNIAGVDPRITELRETRNG---NYEIVNRRTGPARDVRSMAVYE--- 258
Query: 319 SDFLVSGGIEKSLVMCSMSSFAEGNYRKMPLVTPFHKSILVNKQQRLLVMWQDNIVKIWY 378
+ + + G + + C G + M FH+ ++ ++V +N + + +
Sbjct: 259 -NIIFAAGEDFDVYTCK-----SGCQKLM-----FHQQKNLHVASDIVVSAGENYLDVMW 307
Query: 379 IGEDVNEP--------KNYKLV--SKLVLKDEQNIQTCALSTDGQVLLVGRLNTTKVFHL 428
+EP ++Y+++ +K+ ++ I A S G ++ +G + ++ +
Sbjct: 308 KQSGEDEPSEGSVILQQHYEMIHLAKIFTPKKRIITCWAASPYGNLIAIGTCHDVTIYKI 367
Query: 429 QPTDNKL--KVTKLDNEFLLRTGCKFAKFIDDSRLIMCSQSDEIVRIDLEEDDDEKTVTI 486
P K+ KV K + T K + R + E++ DLE ++ ++ +I
Sbjct: 368 SPMVKKINRKVVKTATLDVCATSLSITK---NLRFYVAKSDFEVLEFDLETENGKELKSI 424
Query: 487 ELPEANSTKSSNKLSYL--NAVNHLDANERYAVASRGTGALDL------IDLTTNSSKAL 538
+ +A+ S +S N + L + + TG L ID+T NS+ A
Sbjct: 425 -ISQADCGSVSRMVSSPCGNYICVLTTRSQIFSINTETGESRLLKVDLPIDMTINSTSAF 483
Query: 539 IRMNNFITALCITPRETVVVVTSENKIYEFNLES 572
+ ITP ++ ++ +E NL +
Sbjct: 484 VLST-------ITPNDSNNQQDTKKIFHEVNLSN 510
>Hs13376840 [R] KOG4155 FOG: WD40 repeat
Length = 305
Score = 64.3 bits (155), Expect = 6e-10
Identities = 46/180 (25%), Positives = 82/180 (45%), Gaps = 14/180 (7%)
Query: 102 WDLTTGLPLVNYDCNSGVIWSIAMSNDMNKLAVGCDNGSVVLINISGGKGVLEHESILTR 161
WDL G + + D W++A S D LA G G V + + GK E L
Sbjct: 91 WDLENGKQIKSIDAGPVDAWTLAFSPDSQYLATGTHVGKVNIFGVESGK----KEYSLDT 146
Query: 162 QESRVLSLTWTANDESLVAGCSDGRIRIWYTKEQDENKGRLLHTMKVDKSKKESTLVWSV 221
+ +LS+ ++ + + L +G DG I I+ D G+LLHT+ + + + S+
Sbjct: 147 RGKFILSIAYSPDGKYLASGAIDGIINIF-----DIATGKLLHTL-----EGHAMPIRSL 196
Query: 222 LYLAKQNQIVSGDSTGSVKFWDLNYATLTQSFKVHDADVLCLATDLDNSQLFTSGVDRKI 281
+ +V+ G +K +D+ +A L + H + VL +A D++ +S D+ +
Sbjct: 197 TFSPDSQLLVTASDDGYIKIYDVQHANLAGTLSGHASWVLNVAFCPDDTHFVSSSSDKSV 256
>SPAC227.12 [A] KOG0272 U4/U6 small nuclear ribonucleoprotein Prp4 (contains
WD40 repeats)
Length = 462
Score = 58.9 bits (141), Expect = 3e-08
Identities = 59/248 (23%), Positives = 107/248 (42%), Gaps = 23/248 (9%)
Query: 36 AAPQELRLAIGRSNGNIEIWNPRDDWVQEFVILGGEGRSIEGLSWCSIRGEPLRLFSIGG 95
A ++L LA G ++ + +W Q +L EG + + + L S
Sbjct: 231 ADSEQLTLATGAADNTVCLWKAS----QSTPLLRLEGH-LARVGRVAFHPSGDYLVSASF 285
Query: 96 STVVTEWDLTTGLPLVNYDCNSGVIWSIAMSNDMNKLAVGCDNGSVVLINISGGKGVLEH 155
T WD+ TG+ L+ + +S I+SIA D + ++ G ++ + ++ GK ++
Sbjct: 286 DTTWRLWDVHTGVELLMQEGHSEGIFSIACQPDGSLVSSGGNDAIGRIWDLRSGKSIM-- 343
Query: 156 ESILTRQESRVLSLTWTANDESLVAGCSDGRIRIWYTKEQDENKGRLLHTMKVDKSKKES 215
+L +++++ W+ N L +D ++IW D K L HT+ S
Sbjct: 344 --VLDEHIRQIVAMAWSPNGYQLATSSADDTVKIW-----DLRKVSLAHTIPA-----HS 391
Query: 216 TLVWSVLYLAK--QNQIVSGDSTGSVKFWDLNYATLTQSFKVHDADVLCLATDLDNSQLF 273
+LV V Y+ I + G VK W+ +L +S H+ V ++ D +
Sbjct: 392 SLVSDVRYIESGVNRFIATSGYDGCVKLWNPLNCSLIKSMVGHEEKV--MSVDGYGDRFI 449
Query: 274 TSGVDRKI 281
+SG DR I
Sbjct: 450 SSGYDRTI 457
>Hs8922428 [S] KOG0271 Notchless-like WD40 repeat-containing protein
Length = 485
Score = 55.8 bits (133), Expect = 2e-07
Identities = 56/189 (29%), Positives = 82/189 (42%), Gaps = 31/189 (16%)
Query: 90 LFSIGGSTVVTEWDLTTGLPLVNYDCNSGVIW--SIAMSNDMNKLAVGCDNGSVVLINIS 147
L S G T V WDL+T P ++ C W SI+ S D KLA GC NG ++L + S
Sbjct: 129 LASGSGDTTVRFWDLSTETP--HFTCKGHRHWVLSISWSPDGKKLASGCKNGQILLWDPS 186
Query: 148 GGKGVLEHESILTRQESRVLSLTWT---ANDES--LVAGCSDGRIRIWYTKEQDENKGRL 202
GK V L + L+W AN E + + DG +RIW T +
Sbjct: 187 TGKQV---GRTLAGHSKWITGLSWEPLHANPECRYVASSSKDGSVRIWDTTAGRCERILT 243
Query: 203 LHTMKVDKSKKESTLVW---SVLYLAKQNQIVSGDSTGSVKFWDLNYATLTQSFKVHD-- 257
HT V + L W +LY A Q++ ++K W + L ++ + H
Sbjct: 244 GHTQSV------TCLRWGGDGLLYSASQDR--------TIKVWRAHDGVLCRTLQGHGHW 289
Query: 258 ADVLCLATD 266
+ + L+TD
Sbjct: 290 VNTMALSTD 298
>At5g13840 [DO] KOG0305 Anaphase promoting complex Cdc20 Cdh1 and Ama1
subunits
Length = 472
Score = 52.4 bits (124), Expect = 3e-06
Identities = 58/246 (23%), Positives = 103/246 (41%), Gaps = 30/246 (12%)
Query: 43 LAIGRSNGNIEIWNPRDDWVQEFVILGGEGRSIEGLSWCSIRGEPLRLFSIGG-STVVTE 101
++IG S+G +++W+ + +GG L+W S R+ S G + +
Sbjct: 230 ISIGTSHGQVQVWDGTQ--CKRVRTMGGHQTRTGVLAWNS------RILSSGSRDRNILQ 281
Query: 102 WDLTTGLPLVN-YDCNSGVIWSIAMSNDMNKLAVGCDNGSVVLINISGGKGVLEHESILT 160
D+ V+ + + + S+D +LA G ++ +++ N + +L+ LT
Sbjct: 282 HDIRVQSDFVSKLVGHKSEVCGLKWSHDDRELASGGNDNQLLVWNNHSQQPILK----LT 337
Query: 161 RQESRVLSLTWTANDESLVA---GCSDGRIRIWYTKEQDENKGRLLHTMKVDKSKKESTL 217
+ V ++TW+ + SL+A G +D IR W T G L++ +D + L
Sbjct: 338 EHTAAVKAITWSPHQSSLLASGGGTADRCIRFWNT-----TNGNQLNS--IDTGSQVCNL 390
Query: 218 VWSVLYLAKQNQIVS--GDSTGSVKFWDLNYATLTQSFKVHDADVLCLATDLDNSQLFTS 275
WS N+IVS G S + W + + H VL LAT D + T
Sbjct: 391 AWS----KNVNEIVSTHGYSQNQIMLWKYPSMSKVATLTGHSMRVLYLATSPDGQTIVTG 446
Query: 276 GVDRKI 281
D +
Sbjct: 447 AGDETL 452
>At1g52730 [I] KOG0278 Serine/threonine kinase receptor-associated protein
Length = 381
Score = 52.4 bits (124), Expect = 3e-06
Identities = 46/196 (23%), Positives = 88/196 (44%), Gaps = 25/196 (12%)
Query: 60 DWVQEFVILGGEGRSIEGLSWCS-IRGEPLRLFSIGGSTVVTEWDLTTGLPLVNYDCNSG 118
DW+ F EG +G W S + LR S WD TG L +++ +
Sbjct: 60 DWIGTF-----EGH--KGAVWSSCLDNNALRAASASADFSAKLWDALTGDVLHSFE-HKH 111
Query: 119 VIWSIAMSNDMNKLAVGCDNGSVVLINISGGKGVLEHESILTRQESRVLSLTWTANDESL 178
++ + A S D L G G ++ + + + + + + +LTW +D+++
Sbjct: 112 IVRACAFSEDTKSLLTG---GFEKILRVFDMNRLDAPPTEVDKSPGSIRTLTWLHSDQTI 168
Query: 179 VAGCSD-GRIRIWYTKEQDENKGRLLHTMKVDKSKKESTLVWSVLYLAKQNQIVSGDSTG 237
++ C+D G +R+W D G+++ T++ KS S V ++ + ++
Sbjct: 169 LSSCTDIGGVRLW-----DVRSGKIVQTLET-KSPVTSAEV------SQDGRYITTADGS 216
Query: 238 SVKFWDLNYATLTQSF 253
+VKFWD N+ L +S+
Sbjct: 217 TVKFWDANHFGLVKSY 232
>7290231 [R] KOG4155 FOG: WD40 repeat
Length = 1525
Score = 52.4 bits (124), Expect = 3e-06
Identities = 49/196 (25%), Positives = 84/196 (42%), Gaps = 29/196 (14%)
Query: 38 PQELRLAIGRSNGNIEIWNPRD---------------DWVQEFVILGGEGR--SIEGLSW 80
PQ+ RL IGR +G+I I DW ++ G GR + S
Sbjct: 413 PQQSRLVIGREDGSIVIVPATQTVMMQLLVGIKQNFSDWPSHQILYGHRGRVNCLLCPSM 472
Query: 81 CSIRGEPLRLFSIGGSTVVTEWDLTTGLPLVNYDCNSGVIWSIAMSND------MNKLAV 134
R E L S G V WDL +G L + ++G I + + + + +
Sbjct: 473 IHSRYEKSHLLSGGIDFAVCLWDLYSGSLLHRFCVHAGEITQLLVPPESCSPRILKCICS 532
Query: 135 GCDNGSVVLINISGGKGVLEHESILTRQESRVLSLTWTANDESLVAGCSDGRIRIWYTKE 194
+ SV L+++ K V ++ +R V+++ W D+ L+ GCSDG + +W +
Sbjct: 533 VASDHSVTLVSLQERKCV----TLASRHLFPVVTIKWRPLDDFLIVGCSDGSVYVW--QM 586
Query: 195 QDENKGRLLHTMKVDK 210
+ + R+LH M ++
Sbjct: 587 ETGHLDRVLHGMLAEE 602
>CE06574 [R] KOG0266 WD40 repeat-containing protein
Length = 501
Score = 52.0 bits (123), Expect = 3e-06
Identities = 44/186 (23%), Positives = 80/186 (42%), Gaps = 12/186 (6%)
Query: 81 CSIRGEPLRLFSIGGSTVVTEWDLTTGLPLVNYDCNSGVIWSIAMSNDMNKLAVGCDNGS 140
CS + + S G V WD TGL + +S I SI+ ++D N +A +G
Sbjct: 303 CSFNPQSSLIASAGFDETVRVWDFKTGLCVKCIPAHSDPITSISYNHDGNTMATSSYDGC 362
Query: 141 VVLINISGGKGVLEHESILTRQESRVLSLTWTANDESLVAGCSDGRIRIWYTKEQDENKG 200
+ + + + G + ++++ + V + ++ N + L++ D +++W D K
Sbjct: 363 IRVWDAASGSCL---KTLVDTDHAPVTFVCFSPNGKYLLSAQLDSSLKLW-----DPKKA 414
Query: 201 RLLHTMKVDKSKKESTLVWSVLYLAKQNQIVSGDSTGSVKFWDLNYATLTQSFKVHDADV 260
+ L K+KK + L K I+SG G + W + + Q + H V
Sbjct: 415 KPLKYYNGHKNKKYCLFANMSVPLGK--HIISGSEDGRILVWSIQTKQIVQILEGHTTPV 472
Query: 261 LCLATD 266
LATD
Sbjct: 473 --LATD 476
>CE17294 [S] KOG0271 Notchless-like WD40 repeat-containing protein
Length = 473
Score = 51.2 bits (121), Expect = 6e-06
Identities = 51/186 (27%), Positives = 74/186 (39%), Gaps = 23/186 (12%)
Query: 90 LFSIGGSTVVTEWDLTTGLPLVNYDCNSGVIW--SIAMSNDMNKLAVGCDNGSVVLINIS 147
L S G + WD+ LPL + C S W IA S D K+A C NG + + N
Sbjct: 120 LASGSGDQTMRIWDIELELPL--HTCKSHKSWVLCIAWSPDATKIASACKNGEICIWNAK 177
Query: 148 GGKGVLEHESILTRQESRVLSLTWTANDES----LVAGC-SDGRIRIWYTKEQDENKGRL 202
G+ + L R + + SL W + L+A C DG I IW T + +
Sbjct: 178 TGEQI---GKTLKRHKQWITSLAWQPMHKDPTCRLLASCGKDGNIFIWDTVQGTVVRCLS 234
Query: 203 LHTMKVDKSKKESTLVWSVLYLAKQNQIVSGDSTGSVKFWDLNYATLTQSFKVHDADVLC 262
HT V + L W + I SG +VK W + + ++ H +
Sbjct: 235 GHTASV------TCLRW-----GGEGLIYSGSQDRTVKMWRADDGVMCRNMTGHAHWINT 283
Query: 263 LATDLD 268
LA + D
Sbjct: 284 LALNTD 289
>At3g15610 [I] KOG0278 Serine/threonine kinase receptor-associated protein
Length = 341
Score = 51.2 bits (121), Expect = 6e-06
Identities = 46/196 (23%), Positives = 87/196 (43%), Gaps = 25/196 (12%)
Query: 60 DWVQEFVILGGEGRSIEGLSWCS-IRGEPLRLFSIGGSTVVTEWDLTTGLPLVNYDCNSG 118
DW+ F EG +G W S + LR S WD TG L +++ +
Sbjct: 52 DWIGTF-----EGH--KGAVWSSCLDNNALRAASASADFSAKLWDALTGDVLHSFE-HKH 103
Query: 119 VIWSIAMSNDMNKLAVGCDNGSVVLINISGGKGVLEHESILTRQESRVLSLTWTANDESL 178
++ + A S D L G G ++ + + + + + + +LTW D+++
Sbjct: 104 IVRACAFSQDTKYLITG---GFEKILRVFDLNRLDAPPTEIDKSPGSIRTLTWLHGDQTI 160
Query: 179 VAGCSD-GRIRIWYTKEQDENKGRLLHTMKVDKSKKESTLVWSVLYLAKQNQIVSGDSTG 237
++ C+D G +R+W D G+++ T++ KS S V ++ + ++
Sbjct: 161 LSSCTDIGGVRLW-----DVRSGKIVQTLET-KSPVTSAEV------SQDGRYITTADGS 208
Query: 238 SVKFWDLNYATLTQSF 253
+VKFWD N+ L +S+
Sbjct: 209 TVKFWDANHFGLVKSY 224
>Hs13129110 [A] KOG0284 Polyadenylation factor I complex subunit PFS2
Length = 342
Score = 50.4 bits (119), Expect = 1e-05
Identities = 38/115 (33%), Positives = 52/115 (45%), Gaps = 11/115 (9%)
Query: 163 ESRVLSLTWTANDESLVAGCSDGRIRIWYTKEQDENKGRLLHTMKVDKSKK--ESTLVWS 220
E+ V LTW LVA S G + +W E DEN+ T+ V K K +V +
Sbjct: 80 EAGVADLTWVGERGILVASDS-GAVELW---ELDENE-----TLIVSKFCKYEHDDIVST 130
Query: 221 VLYLAKQNQIVSGDSTGSVKFWDLNYATLTQSFKVHDADVLCLATDLDNSQLFTS 275
V L+ Q VSG +K WDL + S++ H A V C+A +F S
Sbjct: 131 VSVLSSGTQAVSGSKDICIKVWDLAQQVVLSSYRAHAAQVTCVAASPHKDSVFLS 185
>7296695 [A] KOG0284 Polyadenylation factor I complex subunit PFS2
Length = 439
Score = 50.4 bits (119), Expect = 1e-05
Identities = 32/144 (22%), Positives = 66/144 (45%), Gaps = 15/144 (10%)
Query: 120 IWSIAMSNDMNKLAVGCDNGSVVLINISGGKGVLEHESILTRQESRVLSLTWTANDESLV 179
I+++A + + +L G +G L N E+IL + V ++ W+ ND +V
Sbjct: 149 IFTLAWTPEGRRLVTGASSGEFTLWNGL----TFNFETILQAHDISVRTMVWSHNDSWMV 204
Query: 180 AGCSDGRIRIWYTKEQDENKGRLLHTMKVDKSKKESTLVWSVLYLAKQNQIVSGDSTGSV 239
G G ++ W + ++ +K+ ++ KE+ + + + ++ VSG G++
Sbjct: 205 TGDHGGYVKYWQSN---------MNNVKMYQAHKEA--IRGISFSPTDSKFVSGSDDGTL 253
Query: 240 KFWDLNYATLTQSFKVHDADVLCL 263
+ WD + + H ADV C+
Sbjct: 254 RIWDFMRCQEERVLRGHGADVKCV 277
Database: KOG eukaryal database 04/03
Posted date: Apr 14, 2003 1:07 PM
Number of letters in database: 30,389,216
Number of sequences in database: 60,738
Lambda K H
0.318 0.134 0.394
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 42,172,396
Number of Sequences: 60738
Number of extensions: 1766888
Number of successful extensions: 6719
Number of sequences better than 1.0e-05: 18
Number of HSP's better than 0.0 without gapping: 3
Number of HSP's successfully gapped in prelim test: 15
Number of HSP's that attempted gapping in prelim test: 6629
Number of HSP's gapped (non-prelim): 58
length of query: 736
length of database: 30,389,216
effective HSP length: 114
effective length of query: 622
effective length of database: 23,465,084
effective search space: 14595282248
effective search space used: 14595282248
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)