ORF STATUS Function Best COG Functional category Pathways and functional systems
r_klactIV3353 check: MH T KOG1027 Signal transduction mechanisms Serine/threonine protein kinase and endoribonuclease ERN1/IRE1, sensor of the unfolded protein response pathway
Only best alignment is shown:
BLASTP 2.2.3 [May-13-2002]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= r_klactIV3353 1141208 1137753 -1152
(1152 letters)
Database: KOG eukaryal database 04/03
60,738 sequences; 30,389,216 total letters
Searching..................................................done
Color Key for Alignment Scores: 
Score E
Sequences producing significant alignments: (bits) Value
YHR079c [T] KOG1027 Serine/threonine protein kinase and endoribo... 928 0.0
SPAC167.01 [T] KOG1027 Serine/threonine protein kinase and endor... 441 e-123
Hs4557569 [T] KOG1027 Serine/threonine protein kinase and endori... 328 2e-89
7300551 [T] KOG1027 Serine/threonine protein kinase and endoribo... 313 8e-85
Hs15149482 [T] KOG1027 Serine/threonine protein kinase and endor... 311 4e-84
CE01519 [T] KOG1027 Serine/threonine protein kinase and endoribo... 311 5e-84
At5g24360 [T] KOG1027 Serine/threonine protein kinase and endori... 294 6e-79
At2g17520 [T] KOG1027 Serine/threonine protein kinase and endori... 270 1e-71
At3g11870 [T] KOG1027 Serine/threonine protein kinase and endori... 176 2e-43
YPL153c [D] KOG0615 Serine/threonine protein kinase Chk2 and rel... 83 2e-15
7293666 [D] KOG0575 Polo-like serine/threonine protein kinase 82 4e-15
SPAC14C4.03 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase... 81 8e-15
ECU01g0630 [D] KOG0575 Polo-like serine/threonine protein kinase 81 8e-15
SPCC18B5.11c [D] KOG0615 Serine/threonine protein kinase Chk2 an... 80 1e-14
SPBC1D7.05c [T] KOG0198 MEKK and related serine/threonine protei... 77 1e-13
Hs4557439 [R] KOG0594 Protein kinase PCTAIRE and related kinases 77 2e-13
Hs16936528 [R] KOG0594 Protein kinase PCTAIRE and related kinases 75 5e-13
Hs14141724 [T] KOG0033 Ca2+/calmodulin-dependent protein kinase ... 75 5e-13
Hs4502553 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 74 1e-12
At3g48750 [R] KOG0594 Protein kinase PCTAIRE and related kinases 74 1e-12
YOR351c [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-... 74 1e-12
SPAC890.03 [T] KOG0583 Serine/threonine protein kinase 73 2e-12
Hs4759050 [T] KOG0603 Ribosomal protein S6 kinase 73 2e-12
Hs19923570 [T] KOG0603 Ribosomal protein S6 kinase 73 2e-12
CE27297 [D] KOG0615 Serine/threonine protein kinase Chk2 and rel... 73 2e-12
7304358 [T] KOG0033 Ca2+/calmodulin-dependent protein kinase EF-... 73 3e-12
SPAC1F5.09c [T] KOG0578 p21-activated serine/threonine protein k... 72 4e-12
Hs14776113 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase ... 72 4e-12
CE29020 [T] KOG0660 Mitogen-activated protein kinase 72 4e-12
CE28251 [D] KOG0615 Serine/threonine protein kinase Chk2 and rel... 72 4e-12
At1g50700 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 72 4e-12
Hs4505785 [G] KOG0599 Phosphorylase kinase gamma subunit 72 5e-12
CE27768 [R] KOG0586 Serine/threonine protein kinase 72 5e-12
CE23838 [R] KOG0586 Serine/threonine protein kinase 72 5e-12
At3g19100 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 72 5e-12
YDR507c [D] KOG0588 Serine/threonine protein kinase 71 9e-12
Hs4507831 [OUT] KOG0595 Serine/threonine-protein kinase involved... 71 9e-12
Hs20127418 [T] KOG0033 Ca2+/calmodulin-dependent protein kinase ... 71 1e-11
At1g14000 [T] KOG0192 Tyrosine kinase specific for activated (GT... 71 1e-11
7292679 [G] KOG0599 Phosphorylase kinase gamma subunit 71 1e-11
7290342 [G] KOG0658 Glycogen synthase kinase-3 71 1e-11
Hs20070158 [T] KOG0201 Serine/threonine protein kinase 70 1e-11
CE28061 [T] KOG0033 Ca2+/calmodulin-dependent protein kinase EF-... 70 1e-11
CE28060 [T] KOG0033 Ca2+/calmodulin-dependent protein kinase EF-... 70 1e-11
CE28059 [T] KOG0033 Ca2+/calmodulin-dependent protein kinase EF-... 70 1e-11
CE28058 [T] KOG0033 Ca2+/calmodulin-dependent protein kinase EF-... 70 1e-11
CE28057 [T] KOG0033 Ca2+/calmodulin-dependent protein kinase EF-... 70 1e-11
CE28056 [T] KOG0033 Ca2+/calmodulin-dependent protein kinase EF-... 70 1e-11
CE28055 [T] KOG0033 Ca2+/calmodulin-dependent protein kinase EF-... 70 1e-11
CE28054 [T] KOG0033 Ca2+/calmodulin-dependent protein kinase EF-... 70 1e-11
CE28053 [T] KOG0033 Ca2+/calmodulin-dependent protein kinase EF-... 70 1e-11
CE28051 [T] KOG0033 Ca2+/calmodulin-dependent protein kinase EF-... 70 1e-11
7291043 [T] KOG0660 Mitogen-activated protein kinase 70 1e-11
Hs7657526 [T] KOG0603 Ribosomal protein S6 kinase 70 2e-11
Hs4826675 [UT] KOG0662 Cyclin-dependent kinase CDK5 70 2e-11
YOL016c [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-... 69 3e-11
YCR091w [R] KOG0610 Putative serine/threonine protein kinase 69 3e-11
Hs7706286 [T] KOG0033 Ca2+/calmodulin-dependent protein kinase E... 69 3e-11
CE29359 [T] KOG0200 Fibroblast/platelet-derived growth factor re... 69 4e-11
At3g01090 [T] KOG0583 Serine/threonine protein kinase 69 4e-11
SPBC19F8.07 [DKL] KOG0659 Cdk activating kinase (CAK)/RNA polyme... 69 6e-11
At1g53570 [T] KOG0198 MEKK and related serine/threonine protein ... 69 6e-11
7295431 [D] KOG0601 Cyclin-dependent kinase WEE1 69 6e-11
Hs4826684_1 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase... 69 6e-11
YFR014c [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-... 68 7e-11
7297680 [R] KOG0594 Protein kinase PCTAIRE and related kinases 68 7e-11
SPAC23A1.06c [T] KOG0032 Ca2+/calmodulin-dependent protein kinas... 68 1e-10
Hs9966875 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 68 1e-10
CE28650 [OUT] KOG0595 Serine/threonine-protein kinase involved i... 68 1e-10
CE22877 [D] KOG0575 Polo-like serine/threonine protein kinase 68 1e-10
At2g41860 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 68 1e-10
YNR047w [R] KOG0610 Putative serine/threonine protein kinase 67 1e-10
CE28479 [T] KOG0583 Serine/threonine protein kinase 67 1e-10
CE21401 [G] KOG0658 Glycogen synthase kinase-3 67 1e-10
SPAC1687.15 [G] KOG0658 Glycogen synthase kinase-3 67 2e-10
At4g18710 [G] KOG0658 Glycogen synthase kinase-3 67 2e-10
Hs8393810_1 [T] KOG0587 Traf2- and Nck-interacting kinase and re... 67 2e-10
Hs20544910_1 [T] KOG0587 Traf2- and Nck-interacting kinase and r... 67 2e-10
SPAC9G1.02 [T] KOG4645 MAPKKK (MAP kinase kinase kinase) SSK2 an... 67 2e-10
CE08727 [G] KOG0658 Glycogen synthase kinase-3 67 2e-10
At1g49580 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 67 2e-10
At1g35670 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 67 2e-10
At1g12680 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 67 2e-10
YGL179c [T] KOG0585 Ca2+/calmodulin-dependent protein kinase kin... 66 3e-10
SPBC1861.09 [R] KOG0610 Putative serine/threonine protein kinase 66 3e-10
Hs21361643 [T] KOG4717 Serine/threonine protein kinase 66 3e-10
Hs20149547 [T] KOG0603 Ribosomal protein S6 kinase 66 3e-10
At3g29160 [T] KOG0583 Serine/threonine protein kinase 66 4e-10
At2g46700 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 66 4e-10
At2g17890 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 66 4e-10
At1g66880 [T] KOG1187 Serine/threonine protein kinase 66 4e-10
Hs5453882 [G] KOG0599 Phosphorylase kinase gamma subunit 65 5e-10
CE28273 [T] KOG0587 Traf2- and Nck-interacting kinase and relate... 65 5e-10
CE25673 [T] KOG0587 Traf2- and Nck-interacting kinase and relate... 65 5e-10
CE25672 [T] KOG0587 Traf2- and Nck-interacting kinase and relate... 65 5e-10
CE18967 [T] KOG4236 Serine/threonine protein kinase PKC mu/PKD a... 65 5e-10
At4g00720 [G] KOG0658 Glycogen synthase kinase-3 65 5e-10
At2g41140 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 65 5e-10
At1g63700 [T] KOG0198 MEKK and related serine/threonine protein ... 65 5e-10
SPBC11B10.09 [R] KOG0594 Protein kinase PCTAIRE and related kinases 65 6e-10
Hs7662210 [OUT] KOG0595 Serine/threonine-protein kinase involved... 65 6e-10
CE25046 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-... 65 6e-10
CE17815 [K] KOG0666 Cyclin C-dependent kinase CDK8 65 6e-10
At5g23580 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 65 6e-10
At3g10540 [T] KOG0592 3-phosphoinositide-dependent protein kinas... 65 6e-10
At3g08730 [RT] KOG0598 Ribosomal protein S6 kinase and related p... 65 6e-10
7304311 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-... 65 6e-10
SPAC644.06c [D] KOG0588 Serine/threonine protein kinase 64 1e-09
Hs7019543 [T] KOG0582 Ste20-like serine/threonine protein kinase 64 1e-09
Hs6031180 [T] KOG4645 MAPKKK (MAP kinase kinase kinase) SSK2 and... 64 1e-09
Hs5803088 [T] KOG4645 MAPKKK (MAP kinase kinase kinase) SSK2 and... 64 1e-09
Hs4758696 [T] KOG4721 Serine/threonine protein kinase contains l... 64 1e-09
Hs4505695 [T] KOG0592 3-phosphoinositide-dependent protein kinas... 64 1e-09
Hs13899225 [R] KOG0586 Serine/threonine protein kinase 64 1e-09
CE00847 [T] KOG0583 Serine/threonine protein kinase 64 1e-09
At5g24430 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 64 1e-09
At4g36070 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 64 1e-09
SPBC1604.14c [T] KOG0578 p21-activated serine/threonine protein ... 64 1e-09
Hs7706445 [T] KOG0664 Nemo-like MAPK-related serine/threonine pr... 64 1e-09
Hs7705551 [T] KOG0661 MAPK related serine/threonine protein kinase 64 1e-09
Hs5453860 [R] KOG0594 Protein kinase PCTAIRE and related kinases 64 1e-09
Hs15011928 [R] KOG0594 Protein kinase PCTAIRE and related kinases 64 1e-09
At5g66210 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 64 1e-09
At5g39440 [T] KOG0583 Serine/threonine protein kinase 64 1e-09
At3g08720 [RT] KOG0598 Ribosomal protein S6 kinase and related p... 64 1e-09
YHR102w [T] KOG0201 Serine/threonine protein kinase 64 2e-09
SPBC16E9.13 [T] KOG0583 Serine/threonine protein kinase 64 2e-09
HsM5454184 [T] KOG4721 Serine/threonine protein kinase contains ... 64 2e-09
Hs7657335 [T] KOG0587 Traf2- and Nck-interacting kinase and rela... 64 2e-09
Hs4826878 [T] KOG0582 Ste20-like serine/threonine protein kinase 64 2e-09
Hs4506075 [T] KOG4236 Serine/threonine protein kinase PKC mu/PKD... 64 2e-09
Hs21735552 [T] KOG4721 Serine/threonine protein kinase contains ... 64 2e-09
CE20564 [T] KOG0578 p21-activated serine/threonine protein kinase 64 2e-09
CE05425 [T] KOG0578 p21-activated serine/threonine protein kinase 64 2e-09
At5g66850 [T] KOG0198 MEKK and related serine/threonine protein ... 64 2e-09
At5g26751 [G] KOG0658 Glycogen synthase kinase-3 64 2e-09
At3g56760 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 64 2e-09
At1g07880 [T] KOG0660 Mitogen-activated protein kinase 64 2e-09
7293761 [T] KOG4721 Serine/threonine protein kinase contains leu... 64 2e-09
YNL307c [G] KOG0658 Glycogen synthase kinase-3 63 2e-09
HsM4504163 [G] KOG0658 Glycogen synthase kinase-3 63 2e-09
Hs21361340 [G] KOG0658 Glycogen synthase kinase-3 63 2e-09
Hs20545245 [D] KOG0588 Serine/threonine protein kinase 63 2e-09
ECU02g0550 [D] KOG0575 Polo-like serine/threonine protein kinase 63 2e-09
CE18454 [T] KOG4717 Serine/threonine protein kinase 63 2e-09
CE07285 [D] KOG0575 Polo-like serine/threonine protein kinase 63 2e-09
At5g04510 [T] KOG0592 3-phosphoinositide-dependent protein kinas... 63 2e-09
At3g61160 [G] KOG0658 Glycogen synthase kinase-3 63 2e-09
7300224 [T] KOG0201 Serine/threonine protein kinase 63 2e-09
SPBC21.06c [T] KOG0198 MEKK and related serine/threonine protein... 63 3e-09
Hs4557511 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 63 3e-09
Hs4506103 [J] KOG1033 eIF-2alpha kinase PEK/EIF2AK3 63 3e-09
CE25060 [T] KOG0196 Tyrosine kinase EPH (ephrin) receptor family 63 3e-09
CE09940 [D] KOG0601 Cyclin-dependent kinase WEE1 63 3e-09
At5g63610 [K] KOG0666 Cyclin C-dependent kinase CDK8 63 3e-09
At2g42630 [T] KOG0192 Tyrosine kinase specific for activated (GT... 63 3e-09
7290150 [T] KOG0583 Serine/threonine protein kinase 63 3e-09
SPACUNK12.02c [T] KOG0032 Ca2+/calmodulin-dependent protein kina... 62 4e-09
At5g38210 [T] KOG1187 Serine/threonine protein kinase 62 4e-09
7298926 [T] KOG0578 p21-activated serine/threonine protein kinase 62 4e-09
YCL024w [T] KOG0583 Serine/threonine protein kinase 62 5e-09
Hs19923464 [T] KOG0577 Serine/threonine protein kinase 62 5e-09
CE29478 [T] KOG0664 Nemo-like MAPK-related serine/threonine prot... 62 5e-09
CE29477 [T] KOG0664 Nemo-like MAPK-related serine/threonine prot... 62 5e-09
CE29476 [T] KOG0664 Nemo-like MAPK-related serine/threonine prot... 62 5e-09
CE23702 [T] KOG4721 Serine/threonine protein kinase contains leu... 62 5e-09
At3g49370 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 62 5e-09
At3g05840 [G] KOG0658 Glycogen synthase kinase-3 62 5e-09
At1g18390 [T] KOG1187 Serine/threonine protein kinase 62 5e-09
7295638 [T] KOG0603 Ribosomal protein S6 kinase 62 5e-09
YJL106w [T] KOG0661 MAPK related serine/threonine protein kinase 62 7e-09
Hs7662388 [T] KOG0661 MAPK related serine/threonine protein kinase 62 7e-09
Hs22051130 [G] KOG0658 Glycogen synthase kinase-3 62 7e-09
Hs11995474 [G] KOG0658 Glycogen synthase kinase-3 62 7e-09
CE29466 [T] KOG0665 Jun-N-terminal kinase (JNK) 62 7e-09
CE28168 [T] KOG0194 Protein tyrosine kinase 62 7e-09
At4g04710 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 62 7e-09
At1g76040 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 62 7e-09
YBR274w [D] KOG0590 Checkpoint kinase and related serine/threoni... 61 9e-09
Hs4505569 [R] KOG0593 Predicted protein kinase KKIAMRE 61 9e-09
Hs19923468 [T] KOG4236 Serine/threonine protein kinase PKC mu/PK... 61 9e-09
ECU11g1500 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase ... 61 9e-09
7297578 [T] KOG0661 MAPK related serine/threonine protein kinase 61 9e-09
7292249 [T] KOG0587 Traf2- and Nck-interacting kinase and relate... 61 9e-09
YDR477w [T] KOG0583 Serine/threonine protein kinase 61 1e-08
Hs5454094 [T] KOG0574 STE20-like serine/threonine kinase MST 61 1e-08
Hs20479818 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase ... 61 1e-08
Hs20469855 [T] KOG0196 Tyrosine kinase EPH (ephrin) receptor family 61 1e-08
Hs16178962 [T] KOG0574 STE20-like serine/threonine kinase MST 61 1e-08
Hs11496279 [T] KOG0661 MAPK related serine/threonine protein kinase 61 1e-08
CE00315 [R] KOG0594 Protein kinase PCTAIRE and related kinases 61 1e-08
7295173 [T] KOG0664 Nemo-like MAPK-related serine/threonine prot... 61 1e-08
SPCC16C4.11 [R] KOG0594 Protein kinase PCTAIRE and related kinases 60 2e-08
Hs5454096 [T] KOG0574 STE20-like serine/threonine kinase MST 60 2e-08
Hs5453964 [T] KOG0583 Serine/threonine protein kinase 60 2e-08
Hs5031689 [T] KOG4236 Serine/threonine protein kinase PKC mu/PKD... 60 2e-08
At2g30980 [G] KOG0658 Glycogen synthase kinase-3 60 2e-08
7300149 [T] KOG0578 p21-activated serine/threonine protein kinase 60 2e-08
7293496 [R] KOG0597 Serine-threonine protein kinase FUSED 60 2e-08
Hs4507719 [D] KOG0596 Dual specificity; serine/threonine and tyr... 60 2e-08
Hs4502803 [D] KOG0590 Checkpoint kinase and related serine/threo... 60 2e-08
Hs20547712 [D] KOG0596 Dual specificity; serine/threonine and ty... 60 2e-08
CE28571 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-... 60 2e-08
CE01761 [R] KOG0663 Protein kinase PITSLRE and related kinases 60 2e-08
At4g13000 [R] KOG0610 Putative serine/threonine protein kinase 60 2e-08
At4g09570 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 60 2e-08
Hs4502709 [R] KOG0594 Protein kinase PCTAIRE and related kinases 60 3e-08
Hs14196445 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase ... 60 3e-08
ECU08g0230 [R] KOG0594 Protein kinase PCTAIRE and related kinases 60 3e-08
CE29073 [R] KOG0594 Protein kinase PCTAIRE and related kinases 60 3e-08
CE06779 [R] KOG0594 Protein kinase PCTAIRE and related kinases 60 3e-08
At5g18500 [T] KOG1187 Serine/threonine protein kinase 60 3e-08
At3g06030 [T] KOG0198 MEKK and related serine/threonine protein ... 60 3e-08
At1g06390 [G] KOG0658 Glycogen synthase kinase-3 60 3e-08
7295585 [T] KOG0192 Tyrosine kinase specific for activated (GTP-... 60 3e-08
SPCC1259.13 [D] KOG0590 Checkpoint kinase and related serine/thr... 59 3e-08
Hs4506739 [RT] KOG0598 Ribosomal protein S6 kinase and related p... 59 3e-08
Hs4505649 [R] KOG0594 Protein kinase PCTAIRE and related kinases 59 3e-08
CE28740 [T] KOG0592 3-phosphoinositide-dependent protein kinase ... 59 3e-08
CE17284 [T] KOG0583 Serine/threonine protein kinase 59 3e-08
CE12478 [D] KOG0590 Checkpoint kinase and related serine/threoni... 59 3e-08
At5g38260 [T] KOG1187 Serine/threonine protein kinase 59 3e-08
At1g69220 [T] KOG0576 Mitogen-activated protein kinase kinase ki... 59 3e-08
7304283 [Z] KOG0613 Projectin/twitchin and related proteins 59 3e-08
7301004 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-... 59 3e-08
SPBC8D2.19 [T] KOG0661 MAPK related serine/threonine protein kinase 59 4e-08
Hs9994197 [T] KOG0607 MAP kinase-interacting kinase and related ... 59 4e-08
Hs7706401 [T] KOG0577 Serine/threonine protein kinase 59 4e-08
Hs4759208 [T] KOG0577 Serine/threonine protein kinase 59 4e-08
Hs19424132 [D] KOG0591 NIMA (never in mitosis)-related G2-specif... 59 4e-08
Hs16936530 [R] KOG0594 Protein kinase PCTAIRE and related kinases 59 4e-08
CE29612 [R] KOG0594 Protein kinase PCTAIRE and related kinases 59 4e-08
At5g12090 [T] KOG0198 MEKK and related serine/threonine protein ... 59 4e-08
7300650 [R] KOG0594 Protein kinase PCTAIRE and related kinases 59 4e-08
7300435 [T] KOG4645 MAPKKK (MAP kinase kinase kinase) SSK2 and r... 59 4e-08
7294866 [K] KOG0666 Cyclin C-dependent kinase CDK8 59 4e-08
Hs7705841 [T] KOG1187 Serine/threonine protein kinase 59 6e-08
Hs16160923 [R] KOG0594 Protein kinase PCTAIRE and related kinases 59 6e-08
Hs14768528 [T] KOG1187 Serine/threonine protein kinase 59 6e-08
CE26212 [T] KOG0582 Ste20-like serine/threonine protein kinase 59 6e-08
At5g58950 [T] KOG0192 Tyrosine kinase specific for activated (GT... 59 6e-08
At3g54180 [R] KOG0594 Protein kinase PCTAIRE and related kinases 59 6e-08
At2g43790 [T] KOG0660 Mitogen-activated protein kinase 59 6e-08
At2g42960 [T] KOG1187 Serine/threonine protein kinase 59 6e-08
YPL031c [R] KOG0594 Protein kinase PCTAIRE and related kinases 58 8e-08
YKL139w [D] KOG0600 Cdc2-related protein kinase 58 8e-08
YER129w [T] KOG0585 Ca2+/calmodulin-dependent protein kinase kin... 58 8e-08
HsM4758524 [T] KOG0587 Traf2- and Nck-interacting kinase and rel... 58 8e-08
Hs4507361 [T] KOG0192 Tyrosine kinase specific for activated (GT... 58 8e-08
Hs4502745 [K] KOG0666 Cyclin C-dependent kinase CDK8 58 8e-08
Hs22035606 [T] KOG0587 Traf2- and Nck-interacting kinase and rel... 58 8e-08
Hs22035604 [T] KOG0587 Traf2- and Nck-interacting kinase and rel... 58 8e-08
Hs22035602 [T] KOG0587 Traf2- and Nck-interacting kinase and rel... 58 8e-08
Hs21735566 [T] KOG0192 Tyrosine kinase specific for activated (G... 58 8e-08
Hs21735564 [T] KOG0192 Tyrosine kinase specific for activated (G... 58 8e-08
Hs21735562 [T] KOG0192 Tyrosine kinase specific for activated (G... 58 8e-08
Hs20547806 [R] KOG0589 Serine/threonine protein kinase 58 8e-08
CE21879 [D] KOG0590 Checkpoint kinase and related serine/threoni... 58 8e-08
CE05507 [T] KOG0603 Ribosomal protein S6 kinase 58 8e-08
At1g53700 [R] KOG0610 Putative serine/threonine protein kinase 58 8e-08
At1g09840 [G] KOG0658 Glycogen synthase kinase-3 58 8e-08
Hs20428779_1 [T] KOG0587 Traf2- and Nck-interacting kinase and r... 58 8e-08
SPBC8D2.01 [G] KOG0658 Glycogen synthase kinase-3 58 1e-07
HsM4885211 [T] KOG0196 Tyrosine kinase EPH (ephrin) receptor family 58 1e-07
Hs4759052 [T] KOG0603 Ribosomal protein S6 kinase 58 1e-07
Hs21361241 [T] KOG0196 Tyrosine kinase EPH (ephrin) receptor family 58 1e-07
Hs17933758 [T] KOG0585 Ca2+/calmodulin-dependent protein kinase ... 58 1e-07
CE27574 [T] KOG0665 Jun-N-terminal kinase (JNK) 58 1e-07
CE07905 [T] KOG0579 Ste20-like serine/threonine protein kinase 58 1e-07
At4g08500 [T] KOG0198 MEKK and related serine/threonine protein ... 58 1e-07
7294537 [OUT] KOG0595 Serine/threonine-protein kinase involved i... 58 1e-07
7291778 [T] KOG0579 Ste20-like serine/threonine protein kinase 58 1e-07
7291442 [D] KOG0669 Cyclin T-dependent kinase CDK9 58 1e-07
Hs10863929_2 [T] KOG1027 Serine/threonine protein kinase and end... 58 1e-07
Hs4505601 [T] KOG0578 p21-activated serine/threonine protein kinase 57 1e-07
Hs4505153 [T] KOG0198 MEKK and related serine/threonine protein ... 57 1e-07
Hs22057171 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase ... 57 1e-07
Hs20551615 [K] KOG0666 Cyclin C-dependent kinase CDK8 57 1e-07
At5g39020 [T] KOG1187 Serine/threonine protein kinase 57 1e-07
At3g01490 [T] KOG0192 Tyrosine kinase specific for activated (GT... 57 1e-07
At1g57870 [G] KOG0658 Glycogen synthase kinase-3 57 1e-07
7303364 [T] KOG0199 ACK and related non-receptor tyrosine kinases 57 1e-07
7302458 [T] KOG0574 STE20-like serine/threonine kinase MST 57 1e-07
7298766 [T] KOG0200 Fibroblast/platelet-derived growth factor re... 57 1e-07
7292375 [R] KOG0594 Protein kinase PCTAIRE and related kinases 57 1e-07
At3g46920_2 [T] KOG0192 Tyrosine kinase specific for activated (... 57 1e-07
YDL079c [G] KOG0658 Glycogen synthase kinase-3 57 2e-07
YBL105c [T] KOG0694 Serine/threonine protein kinase 57 2e-07
SPCC74.03c [T] KOG0583 Serine/threonine protein kinase 57 2e-07
Hs9910476 [T] KOG0578 p21-activated serine/threonine protein kinase 57 2e-07
Hs5453966 [T] KOG0583 Serine/threonine protein kinase 57 2e-07
CE28643 [T] KOG0583 Serine/threonine protein kinase 57 2e-07
CE27410 [T] KOG0583 Serine/threonine protein kinase 57 2e-07
CE07458 [T] KOG0583 Serine/threonine protein kinase 57 2e-07
At5g20930 [T] KOG1151 Tousled-like protein kinase 57 2e-07
At5g11015 [T] KOG1187 Serine/threonine protein kinase 57 2e-07
At3g45670 [T] KOG0198 MEKK and related serine/threonine protein ... 57 2e-07
At1g54960 [T] KOG0198 MEKK and related serine/threonine protein ... 57 2e-07
7298698 [T] KOG4250 TANK binding protein kinase TBK1 57 2e-07
At2g35050_2 [T] KOG0192 Tyrosine kinase specific for activated (... 57 2e-07
ECU07g1270 [G] KOG0658 Glycogen synthase kinase-3 57 2e-07
ECU02g1450 [DKL] KOG0659 Cdk activating kinase (CAK)/RNA polymer... 57 2e-07
CE29318 [T] KOG0660 Mitogen-activated protein kinase 57 2e-07
At5g07070 [T] KOG0583 Serine/threonine protein kinase 57 2e-07
At3g63260 [T] KOG0192 Tyrosine kinase specific for activated (GT... 57 2e-07
At3g59110 [T] KOG1187 Serine/threonine protein kinase 57 2e-07
At1g49180_1 [OUT] KOG0595 Serine/threonine-protein kinase involv... 57 2e-07
YCR073c [T] KOG4645 MAPKKK (MAP kinase kinase kinase) SSK2 and r... 56 3e-07
SPAC3C7.06c [T] KOG0661 MAPK related serine/threonine protein ki... 56 3e-07
SPAC222.07c [J] KOG1035 eIF-2alpha kinase GCN2 56 3e-07
Hs4885199 [T] KOG1025 Epidermal growth factor receptor EGFR and ... 56 3e-07
CE24516 [OUT] KOG0595 Serine/threonine-protein kinase involved i... 56 3e-07
CE23001 [R] KOG0589 Serine/threonine protein kinase 56 3e-07
CE21213 [UT] KOG0662 Cyclin-dependent kinase CDK5 56 3e-07
CE12518 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-... 56 3e-07
At4g35780 [T] KOG0192 Tyrosine kinase specific for activated (GT... 56 3e-07
At3g59790 [T] KOG0660 Mitogen-activated protein kinase 56 3e-07
7293601 [T] KOG0577 Serine/threonine protein kinase 56 3e-07
YBR160w [R] KOG0594 Protein kinase PCTAIRE and related kinases 56 4e-07
SPBC543.07 [T] KOG0581 Mitogen-activated protein kinase kinase (... 56 4e-07
At3g61960 [OUT] KOG0595 Serine/threonine-protein kinase involved... 56 4e-07
7291302 [T] KOG1025 Epidermal growth factor receptor EGFR and re... 56 4e-07
Hs7662170 [R] KOG0611 Predicted serine/threonine protein kinase 55 5e-07
Hs21735556 [T] KOG0198 MEKK and related serine/threonine protein... 55 5e-07
CE27583 [T] KOG0604 MAP kinase-activated protein kinase 2 55 5e-07
CE23826 [D] KOG0669 Cyclin T-dependent kinase CDK9 55 5e-07
CE18824 [D] KOG0669 Cyclin T-dependent kinase CDK9 55 5e-07
CE18169 [T] KOG0603 Ribosomal protein S6 kinase 55 5e-07
CE17545 [T] KOG0604 MAP kinase-activated protein kinase 2 55 5e-07
CE13014 [T] KOG0603 Ribosomal protein S6 kinase 55 5e-07
At3g50720 [T] KOG0192 Tyrosine kinase specific for activated (GT... 55 5e-07
7297009 [R] KOG0593 Predicted protein kinase KKIAMRE 55 5e-07
YHR030c [T] KOG0660 Mitogen-activated protein kinase 55 6e-07
YAR019c [T] KOG0198 MEKK and related serine/threonine protein ki... 55 6e-07
SPAC4G8.05 [R] KOG0610 Putative serine/threonine protein kinase 55 6e-07
HsM5729922 [T] KOG0198 MEKK and related serine/threonine protein... 55 6e-07
Hs4506401 [T] KOG0193 Serine/threonine protein kinase RAF 55 6e-07
Hs4505599 [T] KOG0578 p21-activated serine/threonine protein kinase 55 6e-07
CE27573 [T] KOG0198 MEKK and related serine/threonine protein ki... 55 6e-07
CE17305 [T] KOG0665 Jun-N-terminal kinase (JNK) 55 6e-07
CE10328 [T] KOG1006 Mitogen-activated protein kinase (MAPK) kina... 55 6e-07
CE07737 [T] KOG0198 MEKK and related serine/threonine protein ki... 55 6e-07
At5g50180 [T] KOG0192 Tyrosine kinase specific for activated (GT... 55 6e-07
At3g45640 [T] KOG0660 Mitogen-activated protein kinase 55 6e-07
At3g07980 [T] KOG0198 MEKK and related serine/threonine protein ... 55 6e-07
At2g31010 [T] KOG0192 Tyrosine kinase specific for activated (GT... 55 6e-07
7303051 [UT] KOG0662 Cyclin-dependent kinase CDK5 55 6e-07
7301110 [T] KOG0660 Mitogen-activated protein kinase 55 6e-07
7300559 [T] KOG4279 Serine/threonine protein kinase 55 6e-07
Hs20070247_2 [RT] KOG0598 Ribosomal protein S6 kinase and relate... 55 6e-07
YGR052w [T] KOG0583 Serine/threonine protein kinase 55 8e-07
Hs7705748 [T] KOG0192 Tyrosine kinase specific for activated (GT... 55 8e-07
Hs7382496 [T] KOG0578 p21-activated serine/threonine protein kinase 55 8e-07
Hs4503787 [T] KOG0197 Tyrosine kinases 55 8e-07
Hs18596354 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase ... 55 8e-07
Hs18552621 [R] KOG0597 Serine-threonine protein kinase FUSED 55 8e-07
CE15235 [R] KOG0589 Serine/threonine protein kinase 55 8e-07
At5g66710 [T] KOG0192 Tyrosine kinase specific for activated (GT... 55 8e-07
At5g50000 [T] KOG0192 Tyrosine kinase specific for activated (GT... 55 8e-07
7300288 [D] KOG0596 Dual specificity; serine/threonine and tyros... 55 8e-07
7297631 [T] KOG0665 Jun-N-terminal kinase (JNK) 55 8e-07
Hs7019547 [T] KOG4250 TANK binding protein kinase TBK1 54 1e-06
Hs5032091 [RT] KOG0598 Ribosomal protein S6 kinase and related p... 54 1e-06
Hs4758298 [T] KOG1025 Epidermal growth factor receptor EGFR and ... 54 1e-06
Hs4506095 [T] KOG0665 Jun-N-terminal kinase (JNK) 54 1e-06
Hs22045050 [T] KOG0671 LAMMER dual specificity kinases 54 1e-06
Hs20986523 [T] KOG0665 Jun-N-terminal kinase (JNK) 54 1e-06
Hs20986521 [T] KOG0665 Jun-N-terminal kinase (JNK) 54 1e-06
Hs20986519 [T] KOG0665 Jun-N-terminal kinase (JNK) 54 1e-06
CE29341 [T] KOG1095 Protein tyrosine kinase 54 1e-06
CE28667 [T] KOG1095 Protein tyrosine kinase 54 1e-06
At5g39030 [T] KOG1187 Serine/threonine protein kinase 54 1e-06
At5g03730 [T] KOG0192 Tyrosine kinase specific for activated (GT... 54 1e-06
At1g67890 [T] KOG0192 Tyrosine kinase specific for activated (GT... 54 1e-06
7302511 [T] KOG0576 Mitogen-activated protein kinase kinase kina... 54 1e-06
YNL298w [T] KOG0578 p21-activated serine/threonine protein kinase 54 1e-06
SPBC119.08 [T] KOG0660 Mitogen-activated protein kinase 54 1e-06
Hs6005810 [T] KOG0576 Mitogen-activated protein kinase kinase ki... 54 1e-06
Hs4885215 [T] KOG1025 Epidermal growth factor receptor EGFR and ... 54 1e-06
Hs20127541 [RT] KOG0598 Ribosomal protein S6 kinase and related ... 54 1e-06
CE27670 [T] KOG0578 p21-activated serine/threonine protein kinase 54 1e-06
CE12408 [T] KOG0661 MAPK related serine/threonine protein kinase 54 1e-06
CE11430 [T] KOG0194 Protein tyrosine kinase 54 1e-06
CE03811 [R] KOG0663 Protein kinase PITSLRE and related kinases 54 1e-06
At5g58380 [T] KOG0583 Serine/threonine protein kinase 54 1e-06
At3g27560 [T] KOG0192 Tyrosine kinase specific for activated (GT... 54 1e-06
At3g06630 [T] KOG0192 Tyrosine kinase specific for activated (GT... 54 1e-06
At1g25390 [T] KOG1187 Serine/threonine protein kinase 54 1e-06
At5g57610_2 [T] KOG0192 Tyrosine kinase specific for activated (... 54 1e-06
YPL140c [T] KOG0581 Mitogen-activated protein kinase kinase (MAP2K) 54 2e-06
SPAC1805.01c [T] KOG1152 Signal transduction serine/threonine ki... 54 2e-06
Hs4506529 [T] KOG0986 G protein-coupled receptor kinase 54 2e-06
Hs4502747 [D] KOG0669 Cyclin T-dependent kinase CDK9 54 2e-06
CE29331 [T] KOG0194 Protein tyrosine kinase 54 2e-06
CE25045 [T] KOG1164 Casein kinase (serine/threonine/tyrosine pro... 54 2e-06
CE18009 [R] KOG0594 Protein kinase PCTAIRE and related kinases 54 2e-06
At5g45430 [T] KOG0661 MAPK related serine/threonine protein kinase 54 2e-06
At4g14780 [T] KOG0192 Tyrosine kinase specific for activated (GT... 54 2e-06
At3g51990 [T] KOG1187 Serine/threonine protein kinase 54 2e-06
At1g73690 [DKL] KOG0659 Cdk activating kinase (CAK)/RNA polymera... 54 2e-06
YDL159w [T] KOG0581 Mitogen-activated protein kinase kinase (MAP2K) 53 2e-06
SPBC1347.06c [T] KOG1165 Casein kinase (serine/threonine/tyrosin... 53 2e-06
CE27177 [T] KOG4279 Serine/threonine protein kinase 53 2e-06
CE20258 [R] KOG0593 Predicted protein kinase KKIAMRE 53 2e-06
CE01405 [T] KOG0577 Serine/threonine protein kinase 53 2e-06
At3g13530 [T] KOG0198 MEKK and related serine/threonine protein ... 53 2e-06
7302199 [T] KOG0197 Tyrosine kinases 53 2e-06
YMR139w [G] KOG0658 Glycogen synthase kinase-3 53 3e-06
Hs4506081 [T] KOG0665 Jun-N-terminal kinase (JNK) 53 3e-06
Hs20986510 [T] KOG0665 Jun-N-terminal kinase (JNK) 53 3e-06
Hs20986506 [T] KOG0665 Jun-N-terminal kinase (JNK) 53 3e-06
Hs14771959 [T] KOG0578 p21-activated serine/threonine protein ki... 53 3e-06
Hs14770402 [R] KOG0586 Serine/threonine protein kinase 53 3e-06
CE07599 [T] KOG0576 Mitogen-activated protein kinase kinase kina... 53 3e-06
CE05098 [T] KOG0194 Protein tyrosine kinase 53 3e-06
At4g24480 [T] KOG0192 Tyrosine kinase specific for activated (GT... 53 3e-06
At3g46930 [T] KOG0192 Tyrosine kinase specific for activated (GT... 53 3e-06
At3g21220 [T] KOG0581 Mitogen-activated protein kinase kinase (M... 53 3e-06
At3g06620 [T] KOG0192 Tyrosine kinase specific for activated (GT... 53 3e-06
7293247 [T] KOG0578 p21-activated serine/threonine protein kinase 53 3e-06
SPBC19C2.05 [T] KOG0583 Serine/threonine protein kinase 52 4e-06
Hs7657214 [T] KOG0583 Serine/threonine protein kinase 52 4e-06
Hs4826776 [T] KOG0197 Tyrosine kinases 52 4e-06
Hs4503069 [T] KOG0660 Mitogen-activated protein kinase 52 4e-06
At5g14640 [G] KOG0658 Glycogen synthase kinase-3 52 4e-06
YHL007c [T] KOG0578 p21-activated serine/threonine protein kinase 52 5e-06
HsM8923212 [T] KOG4717 Serine/threonine protein kinase 52 5e-06
Hs6912584 [R] KOG0594 Protein kinase PCTAIRE and related kinases 52 5e-06
Hs4758008 [T] KOG0671 LAMMER dual specificity kinases 52 5e-06
Hs20986516 [T] KOG0660 Mitogen-activated protein kinase 52 5e-06
Hs20986514 [T] KOG0660 Mitogen-activated protein kinase 52 5e-06
Hs20986512 [T] KOG0660 Mitogen-activated protein kinase 52 5e-06
Hs19923407 [D] KOG0591 NIMA (never in mitosis)-related G2-specif... 52 5e-06
CE27723 [T] KOG0192 Tyrosine kinase specific for activated (GTP-... 52 5e-06
CE06119 [T] KOG0194 Protein tyrosine kinase 52 5e-06
At1g56720 [T] KOG1187 Serine/threonine protein kinase 52 5e-06
Hs7706059 [R] KOG0593 Predicted protein kinase KKIAMRE 52 7e-06
Hs22065589 [T] KOG0587 Traf2- and Nck-interacting kinase and rel... 52 7e-06
Hs14728804 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase ... 52 7e-06
At4g24400 [T] KOG0583 Serine/threonine protein kinase 52 7e-06
At2g18170 [T] KOG0660 Mitogen-activated protein kinase 52 7e-06
At1g51660 [T] KOG0581 Mitogen-activated protein kinase kinase (M... 52 7e-06
7302908 [R] KOG0594 Protein kinase PCTAIRE and related kinases 52 7e-06
7301213 [R] KOG0589 Serine/threonine protein kinase 52 7e-06
7290903 [T] KOG0192 Tyrosine kinase specific for activated (GTP-... 52 7e-06
HsM20070143 [T] KOG0665 Jun-N-terminal kinase (JNK) 51 9e-06
Hs7661994 [T] KOG0579 Ste20-like serine/threonine protein kinase 51 9e-06
Hs21237745 [T] KOG0665 Jun-N-terminal kinase (JNK) 51 9e-06
Hs21237742 [T] KOG0665 Jun-N-terminal kinase (JNK) 51 9e-06
Hs21237739 [T] KOG0665 Jun-N-terminal kinase (JNK) 51 9e-06
Hs21237736 [T] KOG0665 Jun-N-terminal kinase (JNK) 51 9e-06
Hs17452757 [UT] KOG0662 Cyclin-dependent kinase CDK5 51 9e-06
CE26076 [D] KOG0590 Checkpoint kinase and related serine/threoni... 51 9e-06
At5g58940 [T] KOG1187 Serine/threonine protein kinase 51 9e-06
7298087 [T] KOG0660 Mitogen-activated protein kinase 51 9e-06
7298004 [G] KOG0658 Glycogen synthase kinase-3 51 9e-06
CE27894_1 [R] KOG0589 Serine/threonine protein kinase 51 9e-06
>YHR079c [T] KOG1027 Serine/threonine protein kinase and endoribonuclease
ERN1/IRE1 sensor of the unfolded protein response pathway
Length = 1115
Score = 928 bits (2399), Expect = 0.0
Identities = 488/1030 (47%), Positives = 677/1030 (65%), Gaps = 33/1030 (3%)
Query: 137 ANSLIAISGNIRDLSALKLSDILIATDIEGGLHGIDRASGRLLWSIDRPELPPLLEIRHP 196
ANS+ R L+ L LSDILIA D+EGGLH +DR +G ++WSI+ PL+EI+ P
Sbjct: 101 ANSISVPYLENRSLNELSLSDILIAADVEGGLHAVDRRNGHIIWSIEPENFQPLIEIQEP 160
Query: 197 SSIVN-ETLIVEPYGDGNVFYFNPYQGLQKLPVSIKHLVEASPLSIKSKIVVDDLGTVIE 255
S + ETLI+EP+GDGN++YFN +QGLQKLP+SI+ LV SPL +K+ IVV+D G ++E
Sbjct: 161 SRLETYETLIIEPFGDGNIYYFNAHQGLQKLPLSIRQLVSTSPLHLKTNIVVNDSGKIVE 220
Query: 256 DEKIYTGSRRTDLYTIDTVTGEIISAFGPGTENKVYNKDKVECTGY--LGTNECENIVVI 313
DEK+YTGS RT +YTI+ + GEIISAFGPG++N + V+C+ + ECEN++VI
Sbjct: 221 DEKVYTGSMRTIMYTINMLNGEIISAFGPGSKNGYFGSQSVDCSPEEKIKLQECENMIVI 280
Query: 314 GKTNYELTIHSNEQTLYNVKYSQWQHNTLVNHLASQNLVSRDGVYIAPFKDKSLVAIDTD 373
GKT +EL IHS + YNV YS WQ N L LA QN S+DG+ IAPF+DKSL+A D D
Sbjct: 281 GKTIFELGIHSYDGASYNVTYSTWQQNVLDVPLALQNTFSKDGMCIAPFRDKSLLASDLD 340
Query: 374 FNLAKWVCPNLPAIINNVFDIYIDYSTEEKVLLPHPHQIVNDIDDVAEEDFQVYVDLTED 433
F +A+WV P P II +FD++ D T E +L+PHP N D + +VY+D T +
Sbjct: 341 FRIARWVSPTFPGIIVGLFDVFNDLRTNENILVPHPF---NPGDHESISSNKVYLDQTSN 397
Query: 434 GTWFALSSDYFSSLVNAAPTSKFSLNSRWRQPEIFHDPLLLRMSIIGVHHLNLQQYRKVL 493
+WFALSS F SLV +AP S+++ + RWR IF D L + +I+GVH + +Y +
Sbjct: 398 LSWFALSSQNFPSLVESAPISRYASSDRWRVSSIFEDETLFKNAIMGVHQIYNNEYDHLY 457
Query: 494 INNEPYSTVPSLPSGPESNYPPALPGVS-PSEDLSK-----SIGKYISPEELQ----RIQ 543
N E +++ + YPP + S + DL + S+ +Y+SPE+L+ +I
Sbjct: 458 ENYEKTNSLDTT-----HKYPPLMIDSSVDTTDLHQNNEMNSLKEYMSPEDLEAYRKKIH 512
Query: 544 EQLAKTINEE-QNSLTNRISNSIIRIVESGLMMVLAVFLLYILASLNVIPPLHVLLTEIG 602
EQ+++ ++E+ QNSL + + + RI+E+G+ ++L + IL ++PPL+VLL++IG
Sbjct: 513 EQISRELDEKNQNSLLLKFGSLVYRIIETGVFLLLFLIFCAILQRFKILPPLYVLLSKIG 572
Query: 603 ILPKVQIPTQEVKIDTAISHKVNTNDIGKELSEKNTGNQDLPFDQNEGVSSETGTGDFEA 662
+P+ +IP E K +++ ++ ++ K K+ N+G D
Sbjct: 573 FMPEKEIPIVESK---SLNCPSSSENVTKPFDMKSGKQVVFEGAVNDGSLKSEKDNDDAD 629
Query: 663 XXXXXXXXXXXXXXXXXXXXXXXXLDDDGPMLDFKEFEQEGHLKHLSISSRVLGYGSSGT 722
+ + FEQ LK+L +S ++LGYGSSGT
Sbjct: 630 EDDEKSLDLTTEKKKRKRGSRGGKKGRKSRIANIPNFEQS--LKNLVVSEKILGYGSSGT 687
Query: 723 VVFQGKFQNRPVAVKRLLIDFYDIASKEIQLLSESDDHPNVIRYYFSESTEKFMYIAVEL 782
VVFQG FQ RPVAVKR+LIDF DIA EI+LL+ESDDHPNVIRYY SE+T++F+YIA+EL
Sbjct: 688 VVFQGSFQGRPVAVKRMLIDFCDIALMEIKLLTESDDHPNVIRYYCSETTDRFLYIALEL 747
Query: 783 CSASLEDVIEGSKGLAKNVAVQKNIDPINVLFQITSGVNHLHSMKIVHRDLKPQNILIAP 842
C+ +L+D++E +N+ +QK +PI++L QI SGV HLHS+KI+HRDLKPQNIL++
Sbjct: 748 CNLNLQDLVESKNVSDENLKLQKEYNPISLLRQIASGVAHLHSLKIIHRDLKPQNILVST 807
Query: 843 PKRYLS-LHASKNKFRVLISDFGLCKKLEIDESSFRTNNFNNPTGTSGWRAPEIISGEVS 901
R+ + R+LISDFGLCKKL+ +SSFRTN NNP+GTSGWRAPE++ +
Sbjct: 808 SSRFTADQQTGAENLRILISDFGLCKKLDSGQSSFRTN-LNNPSGTSGWRAPELLEESNN 866
Query: 902 LSESFAXXXXXXXXXXXXXXLDVNHMDLVTKKRLTRAVDIFSLGCIFYYVLSKGEHPFGD 961
L + D TK+RLTR++DIFS+GC+FYY+LSKG+HPFGD
Sbjct: 867 LQCQVETEHSSSRHTVVSSD---SFYDPFTKRRLTRSIDIFSMGCVFYYILSKGKHPFGD 923
Query: 962 RILREANILKGDYRLDGIKKSIQERSVCIEAADLIKSMLEQNPLLRPASDEILKHPLFWG 1021
+ RE+NI++G + LD +K + +RS+ EA DLI M++ +PL RP + ++L+HPLFW
Sbjct: 924 KYSRESNIIRGIFSLDEMK-CLHDRSLIAEATDLISQMIDHDPLKRPTAMKVLRHPLFWP 982
Query: 1022 VSKKLEFLLKVSDRFEVERRDPPSPLLLKLEEVSAKVITTGDWSMKFDAVFMENLGKYRK 1081
SKKLEFLLKVSDR E+E RDPPS LL+K + S VI +GDW++KFD FM+NL +YRK
Sbjct: 983 KSKKLEFLLKVSDRLEIENRDPPSALLMKFDAGSDFVIPSGDWTVKFDKTFMDNLERYRK 1042
Query: 1082 YKGEKLMDLLRALRNKYHHFRDLPDELAEVMGPIPDGFYKYFIQRFPNLLMEIYYVVDRN 1141
Y KLMDLLRALRNKYHHF DLP+++AE+MGP+PDGFY YF +RFPNLL+ +Y +V N
Sbjct: 1043 YHSSKLMDLLRALRNKYHHFMDLPEDIAELMGPVPDGFYDYFTKRFPNLLIGVYMIVKEN 1102
Query: 1142 LKDDQVLSEF 1151
L DDQ+L EF
Sbjct: 1103 LSDDQILREF 1112
>SPAC167.01 [T] KOG1027 Serine/threonine protein kinase and endoribonuclease
ERN1/IRE1 sensor of the unfolded protein response pathway
Length = 1072
Score = 441 bits (1134), Expect = e-123
Identities = 342/1121 (30%), Positives = 530/1121 (46%), Gaps = 186/1121 (16%)
Query: 123 SSKVSREEVIVNDKANSLIAISGNIRDLSA------LKLSDILIATDIEGGLHGIDRASG 176
+ K + E + + A+S ++ G + SA L + I ++G LH DR +G
Sbjct: 43 NGKANNELALFSPTADSPSSVDGVLELPSAENVFAESSLYNAFIVATVDGSLHSYDRITG 102
Query: 177 RLLWSIDRPELPPLLEIRHPSSIVNETLI------------------------------- 205
+ LWS+ P L + +S+++ +
Sbjct: 103 QELWSLFTNANPGLSYTKDENSLLSSKFLSQSNFKSYNSTHGEFYSDSTLNISYLSDDDT 162
Query: 206 ---VEPYGDGNVFYFNPYQGLQKLPVSIKHLVEASPLSIKSKIVVDDLGTVIEDEKIYTG 262
VEP G ++ FN GL +LP SIK LV ASP+ + + ++ G
Sbjct: 163 VWFVEPIDGGILYAFNLQTGLVRLPHSIKDLVHASPIRLLNN-------------NVFVG 209
Query: 263 SRRTDLYTIDTVTGEIISAFGPG----TENKVYNK------------------------- 293
S+ T L+TID G+I+S + G T + V+N
Sbjct: 210 SKNTTLFTIDVSNGDIVSQYPSGHRYETHHSVHNLGTKRDSVPSGADSDLSFKDPSGKKL 269
Query: 294 ----DKVECTGYLGTNECENIVVIGKTNYELTIHSNEQTLYNVKYSQWQHNTLVNHLASQ 349
D ++ Y T ++ V I +T Y +TI+S+ + ++ Y W S
Sbjct: 270 SESLDLLDDFNYQVTVSNKSFVDIARTEYFITIYSDSNVILDLVYIDWTPTKNEIMYESF 329
Query: 350 NLVSRDGVYIAPFKDKSLVAIDTDFNLAKWVCPNLPAI--INNVFDIY-------IDYST 400
+ S D D SL +DT +K++ N+P + VFDI ID S
Sbjct: 330 HSSSFDSKLALSSYDSSLHIVDTH---SKFIKQNIPLMSPAATVFDIVTLPHNKKIDKS- 385
Query: 401 EEKVLLPHPHQIVNDIDDVAEEDF-QVYVDLTED-------GTWFALSSDYFSSLVNAAP 452
+ P + ID E F Q+ + TE WFA+S ++ LV+ AP
Sbjct: 386 QTPAKFPTSVLLRQPIDTYLETMFPQIARNKTEHVYINHIGNAWFAMSERHYP-LVSLAP 444
Query: 453 TSKFSLNSRWRQPEIFHDPLLLRMSIIGVHHLNLQQYRKVLINNEPYSTVPSLPSGPESN 512
+ F + F+ PL SI G+H L + +P+ +P LP +
Sbjct: 445 EASFLYYNG------FYIPL---NSIFGLHSL--------MATPKPFFALPGLPGYDIPS 487
Query: 513 YPPALPGVSPSEDLSKSIGKYISPEELQRIQEQLAKTINEEQNSLTNRISNSIIRIVESG 572
Y + + K + P N IS++ I I
Sbjct: 488 YVESEGSTKTLPSIGKKPIPLLDP----------------------NPISSTPISITFWV 525
Query: 573 LMMVLAVFLLYILASLNVIPPLHVLLTEIGILPKVQIPTQEV--KIDTAISHKVNTNDIG 630
+M + F + S+ L + +E+ L K Q T + KIDT S +
Sbjct: 526 IMFLSVSFTIVTFFSI-----LRIRSSEVRPL-KSQKNTVSINNKIDT--SKRRRKGKRR 577
Query: 631 KELSEKNTGNQDLPFDQNEGVSSETGTGDFEAXXXXXXXXXXXXXXXXXXXXXXXXLDDD 690
K +S++++ + + +++ + T D + +
Sbjct: 578 KRVSDEHSASSNFNEIESQASFEQNQTLDILSENIVEIQDKSTDPLQKSLDSSLKSHLPE 637
Query: 691 GPMLDFKEFEQEGHLKHLSISSRVLGYGSSGTVVFQGKFQNRPVAVKRLLIDFYDIASKE 750
++ + + + L++ V+GYGS GT+V++G +++R VAVKR+L++FYD+AS+E
Sbjct: 638 ATVI--QNTDGSVTVNSLTVYPEVIGYGSHGTIVYRGVYEDREVAVKRVLMEFYDLASRE 695
Query: 751 IQLLSESDDHPNVIRYYFSESTEKFMYIAVELCSASLEDVIEGSKGLAKNVAVQKNIDPI 810
I LL +SD+HPN++RYY + +++F+YI +ELC +L D+IE K +A + + K+ID +
Sbjct: 696 ITLLQQSDNHPNIVRYYCKQKSDQFLYIVIELCKCNLSDLIE--KPIAYD-DLFKSIDLV 752
Query: 811 NVLFQITSGVNHLHSMKIVHRDLKPQNILIAPPKRYLSLHASKNKFRVLISDFGLCKKLE 870
++L+QI GV+HLHS+ +VHRDLKPQNIL+ S + SK + R LISDFGL KKL+
Sbjct: 753 SLLYQIAFGVSHLHSLDLVHRDLKPQNILLVVNN---SPNLSKTRVRALISDFGLSKKLD 809
Query: 871 IDESSFRTNNFNNPTGTSGWRAPEIISGEVSLSESFAXXXXXXXXXXXXXXLDVNHMDLV 930
++SS R F G+ GWR+PEI+SG +S
Sbjct: 810 FNQSSLRNTTFE-AAGSYGWRSPEILSGSLSQQSKEIQVKTREGRI-------------- 854
Query: 931 TKKRLTRAVDIFSLGCIFYYVLSKGEHPFGDRILREANILKGDYRLDGIKKSIQERSVCI 990
++ + A DIF+LGCIFYY L+ G HPFG E NILKG+Y L ++ S+ E V
Sbjct: 855 --RQASHATDIFALGCIFYYTLTGGMHPFGSHYDCEGNILKGNYCLVHLQ-SLGECGVL- 910
Query: 991 EAADLIKSMLEQNPLLRPASDEILKHPLFWGVSKKLEFLLKVSDRFEVERRDPPSPLLLK 1050
AADLI+ M+ P RP + +L HPLFW +KKL+FL+ VSDRFEVE RDPPSPLL
Sbjct: 911 -AADLIEDMIAFEPSKRPTIEVVLNHPLFWDYAKKLDFLIDVSDRFEVEERDPPSPLLQM 969
Query: 1051 LEEVSAKVITTGDWSMKFDAVFMENLGKYRKYKGEKLMDLLRALRNKYHHFRDLPDELAE 1110
LE S VI +W+ + ++NLGKYRKY G K++D+LR LRNK HH++DLP+ +
Sbjct: 970 LENNSKSVIGE-NWTTCLHSSLVDNLGKYRKYDGSKILDILRVLRNKRHHYQDLPESVRR 1028
Query: 1111 VMGPIPDGFYKYFIQRFPNLLMEIYYVVDRNLKDDQVLSEF 1151
V+G +PDGF YF+++FP LL+ Y++V L ++ +
Sbjct: 1029 VLGDLPDGFTSYFVEKFPMLLLHCYHLVKDVLYEESQFKRY 1069
>Hs4557569 [T] KOG1027 Serine/threonine protein kinase and endoribonuclease
ERN1/IRE1 sensor of the unfolded protein response pathway
Length = 977
Score = 328 bits (842), Expect = 2e-89
Identities = 179/426 (42%), Positives = 250/426 (58%), Gaps = 52/426 (12%)
Query: 714 VLGYGSSGTVVFQGKFQNRPVAVKRLLIDFYDIASKEIQLLSESDDHPNVIRYYFSESTE 773
VLG+G+ GT+V++G F NR VAVKR+L + + A +E+QLL ESD+HPNVIRY+ +E
Sbjct: 576 VLGHGAEGTIVYRGMFDNRDVAVKRILPECFSFADREVQLLRESDEHPNVIRYFCTEKDR 635
Query: 774 KFMYIAVELCSASLEDVIEGSKGLAKNVAVQKNIDPINVLFQITSGVNHLHSMKIVHRDL 833
+F YIA+ELC+A+L++ +E K+ A ++PI +L Q TSG+ HLHS+ IVHRDL
Sbjct: 636 QFQYIAIELCAATLQEYVE-----QKDFA-HLGLEPITLLQQTTSGLAHLHSLNIVHRDL 689
Query: 834 KPQNILIAPPKRYLSLHASKNKFRVLISDFGLCKKLEIDESSFRTNNFNNPTGTSGWRAP 893
KP NILI+ P + K + +ISDFGLCKKL + SF + GT GW AP
Sbjct: 690 KPHNILISMPNAH-------GKIKAMISDFGLCKKLAVGRHSFSRRS--GVPGTEGWIAP 740
Query: 894 EIISGEVSLSESFAXXXXXXXXXXXXXXLDVNHMDLVTKKRLTRAVDIFSLGCIFYYVLS 953
E++S + K+ T VDIFS GC+FYYV+S
Sbjct: 741 EMLSEDC-------------------------------KENPTYTVDIFSAGCVFYYVVS 769
Query: 954 KGEHPFGDRILREANILKGDYRLDGIKKSIQERSVCIEAADLIKSMLEQNPLLRPASDEI 1013
+G HPFG + R+ANIL G LD + E + A +LI+ M+ +P RP+++++
Sbjct: 770 EGSHPFGKSLQRQANILLGACSLDCLHPEKHEDVI---ARELIEKMIAMDPQKRPSANDV 826
Query: 1014 LKHPLFWGVSKKLEFLLKVSDRFEVERRDPPSPLLLKLEEVSAKVITTGDWSMKFDAVFM 1073
LKHP FW + K+L+F VSDR E E D P ++K E + + DW
Sbjct: 827 LKHPFFWSLEKQLQFFQDVSDRIEKESLDGP---IVKQLERGGRAVVKMDWRENITDPLQ 883
Query: 1074 ENLGKYRKYKGEKLMDLLRALRNKYHHFRDLPDELAEVMGPIPDGFYKYFIQRFPNLLME 1133
+L K+R YKG + DLLRA+RNK HH+R+LP E+ E +G +PD F YF RFP+LL
Sbjct: 884 TDLRKFRTYKGGSVRDLLRAMRNKKHHYRELPAEVRETLGTLPDDFVCYFTSRFPHLLAH 943
Query: 1134 IYYVVD 1139
Y ++
Sbjct: 944 TYRAME 949
>7300551 [T] KOG1027 Serine/threonine protein kinase and endoribonuclease
ERN1/IRE1 sensor of the unfolded protein response pathway
Length = 1009
Score = 313 bits (803), Expect = 8e-85
Identities = 182/428 (42%), Positives = 247/428 (57%), Gaps = 53/428 (12%)
Query: 711 SSRVLGYGSSGTVVFQGKFQNRPVAVKRLLIDFYDIASKEIQLLSESDDHPNVIRYYFSE 770
++ VLG G GT VF+G F+ R VAVKRLL + + A +E+ LL ESD H NV+RY+ +E
Sbjct: 485 TNEVLGKGCEGTFVFKGTFEERFVAVKRLLPECFTFADREVALLRESDAHENVVRYFCTE 544
Query: 771 STEKFMYIAVELCSASLEDVIEGSKGLAKNVAVQKNIDPINVLFQITSGVNHLHSMKIVH 830
+F YIAVELC+A+L+D EG + L +Q +ID VL Q SG++HLHS+ IVH
Sbjct: 545 QDRQFRYIAVELCAATLQDYTEGDRSL----ELQNHIDVWQVLSQAASGLSHLHSLDIVH 600
Query: 831 RDLKPQNILIAPPKRYLSLHASKNKFRVLISDFGLCKKLEIDESSFRTNNFNNPTGTSGW 890
RD+KPQN+LI SL +K K RV+ISDFGLCKKL ++SF + + TGT GW
Sbjct: 601 RDIKPQNVLI-------SLPDAKGKVRVMISDFGLCKKLNFGKTSF--SRRSGVTGTDGW 651
Query: 891 RAPEIISGEVSLSESFAXXXXXXXXXXXXXXLDVNHMDLVTKKRLTRAVDIFSLGCIFYY 950
APE ++ +R T AVDIFSLGC++YY
Sbjct: 652 IAPE----------------------------------MMRSQRTTTAVDIFSLGCVYYY 677
Query: 951 VLSKGEHPFGDRILREANILKGDYRLDGIK-KSIQERSVCIEAADLIKSMLEQNPLLRPA 1009
VLS G H FGD + R+ANIL +Y L ++ + E S I A LI M+ ++P RP
Sbjct: 678 VLSGGHHAFGDNLKRQANILSHEYNLAKLRPEDDSEDSRIILAEQLISDMIHKDPQSRPP 737
Query: 1010 SDEILKHPLFWGVSKKLEFLLKVSDRFE-VERRDPPSPLLLKLEEVSAKVITTGDWSMKF 1068
+ I HPLFW K L FL VSDR E ++ P LK E + +++ DW++
Sbjct: 738 ARCIGNHPLFWDEPKMLSFLQDVSDRVEKLQFHAEP----LKSLEKNGRIVVLDDWNVHL 793
Query: 1069 DAVFMENLGKYRKYKGEKLMDLLRALRNKYHHFRDLPDELAEVMGPIPDGFYKYFIQRFP 1128
D + ++L KYR Y G + DLLRALRNK HH+ +L +++G IP F Y++ RFP
Sbjct: 794 DPMITDDLRKYRGYMGASVRDLLRALRNKKHHYHELTPAAQKMLGCIPHEFTNYWVDRFP 853
Query: 1129 NLLMEIYY 1136
L+ Y+
Sbjct: 854 QLISHAYH 861
>Hs15149482 [T] KOG1027 Serine/threonine protein kinase and endoribonuclease
ERN1/IRE1 sensor of the unfolded protein response pathway
Length = 925
Score = 311 bits (797), Expect = 4e-84
Identities = 180/446 (40%), Positives = 253/446 (56%), Gaps = 53/446 (11%)
Query: 694 LDFKEFEQEGHLKHLSISSR-VLGYGSSGTVVFQGKFQNRPVAVKRLLIDFYDIASKEIQ 752
LD E EQ + +S + + VLG+G+ GT VF+G+F+ R VAVKRLL + + + +E+Q
Sbjct: 503 LDDPEAEQLTVVGKISFNPKDVLGHGAGGTFVFRGQFEGRAVAVKRLLRECFGLVRREVQ 562
Query: 753 LLSESDDHPNVIRYYFSESTEKFMYIAVELCSASLEDVIEGSKGLAKNVAVQKNIDPINV 812
LL ESD HPNV+RY+ +E +F YIA+ELC ASL++ +E + ++P V
Sbjct: 563 LLQESDRHPNVLRYFCTERGPQFHYIALELCRASLQEYVENPD------LDRGGLEPEVV 616
Query: 813 LFQITSGVNHLHSMKIVHRDLKPQNILIAPPKRYLSLHASKNKFRVLISDFGLCKKLEID 872
L Q+ SG+ HLHS+ IVHRDLKP NILI P ++ RV++SDFGLCKKL
Sbjct: 617 LQQLMSGLAHLHSLHIVHRDLKPGNILITGPD-------TQGLGRVVLSDFGLCKKLPAG 669
Query: 873 ESSFRTNNFNNPTGTSGWRAPEIISGEVSLSESFAXXXXXXXXXXXXXXLDVNHMDLVTK 932
SF ++ GT GW APE++ L+
Sbjct: 670 RCSFSLHS--GIPGTEGWMAPELLQ-------------------------------LLPP 696
Query: 933 KRLTRAVDIFSLGCIFYYVLSKGEHPFGDRILREANILKGDYRLDGIKKSIQERSVCIEA 992
T AVDIFS GC+FYYVLS G HPFGD + R+ANIL G L +++ + ++ V A
Sbjct: 697 NSPTSAVDIFSAGCVFYYVLSGGSHPFGDSLYRQANILTGVPCLAHLEEEVHDKVV---A 753
Query: 993 ADLIKSMLEQNPLLRPASDEILKHPLFWGVSKKLEFLLKVSDRFEVERRDPPSPLLLKLE 1052
DL+ +ML P RP++ ++L HP FW +K+L+F VSD E E P L++
Sbjct: 754 RDLVAAMLSLLPQARPSAPQVLAHPFFWSRAKQLQFFQDVSDWLEKESEQEP---LMRAL 810
Query: 1053 EVSAKVITTGDWSMKFDAVFMENLGKYRKYKGEKLMDLLRALRNKYHHFRDLPDELAEVM 1112
E + +W +L K+R YKG + DLLRA+RNK HH+R+LP E+ + +
Sbjct: 811 EAGGCTVVRDNWHEHISMPLQIDLRKFRSYKGTSVRDLLRAVRNKKHHYRELPVEVRQAL 870
Query: 1113 GPIPDGFYKYFIQRFPNLLMEIYYVV 1138
G +PDGF +YF RFP LL+ + V+
Sbjct: 871 GQVPDGFVQYFTNRFPQLLLHTHRVM 896
>CE01519 [T] KOG1027 Serine/threonine protein kinase and endoribonuclease
ERN1/IRE1 sensor of the unfolded protein response pathway
Length = 983
Score = 311 bits (796), Expect = 5e-84
Identities = 174/424 (41%), Positives = 249/424 (58%), Gaps = 53/424 (12%)
Query: 712 SRVLGYGSSGTVVFQGKFQNRPVAVKRLLIDFYDIASKEIQLLSESDDHPNVIRYYFSES 771
S +LG G GTVV++G F R VAVKR++ +F A +E LL ESD HP+VIRY+ ES
Sbjct: 537 SDILGTGCEGTVVYRGTFDGREVAVKRVVSEFVKFAHREADLLRESDTHPHVIRYFCMES 596
Query: 772 TEKFMYIAVELCSASLEDVIEGSKGLAKNVAVQKNIDPINVLFQITSGVNHLHSMKIVHR 831
+F Y+A+ELC ASL D +E K + +NV + +++ Q T G+ HLH+ KIVHR
Sbjct: 597 DSQFRYLALELCIASLNDYVE-QKEVQQNVTIALR----DIMKQATDGLAHLHASKIVHR 651
Query: 832 DLKPQNILIAPPKRYLSLHASKNKFRVLISDFGLCKKLEIDESSFRTNNFNNPTGTSGWR 891
D+KPQN+LI ++ + + + R +ISDFGLCK+++ ++S + GT GW
Sbjct: 652 DMKPQNVLI-------TMASQRGEMRAVISDFGLCKRVQPGKNSISRGIASGLAGTDGWI 704
Query: 892 APEIISGEVSLSESFAXXXXXXXXXXXXXXLDVNHMDLVTKKRLTRAVDIFSLGCIFYYV 951
APE++ +S S S+ VDIFSLGCIFYYV
Sbjct: 705 APEVL---ISASTSYP-------------------------------VDIFSLGCIFYYV 730
Query: 952 LSKGEHPFGDRILREANILKGDYRLDGIKKSIQERSVCIEAADLIKSMLEQNPLLRPASD 1011
L+ G HPFG + R+ANI+ G+Y L+ + + + S+ A DLI SML PL R +D
Sbjct: 731 LTSGTHPFGKSLHRQANIVNGEYTLNKLA-DLDDWSL---ADDLISSMLNVEPLHRLTAD 786
Query: 1012 EILKHPLFWGVSKKLEFLLKVSDRFEVERRDPPSPLLLKLEEVSAKVITTGDWSMKFDAV 1071
+L HP FW K+L + VSDR VE+ + SP++ ++E A+++ G W K
Sbjct: 787 AVLNHPFFWTSEKRLAYFSDVSDR--VEKEEDNSPVVRRIE-TDARIVVCGGWREKICDA 843
Query: 1072 FMENLGKYRKYKGEKLMDLLRALRNKYHHFRDLPDELAEVMGPIPDGFYKYFIQRFPNLL 1131
E+L K+R YK + DLLRA+RNK HH+R+LP+++ + +G IPD F YF RFP LL
Sbjct: 844 LKEDLRKFRTYKSFSVRDLLRAMRNKKHHYRELPEDVRQSLGDIPDQFLHYFTSRFPRLL 903
Query: 1132 MEIY 1135
+ +Y
Sbjct: 904 LHVY 907
>At5g24360 [T] KOG1027 Serine/threonine protein kinase and endoribonuclease
ERN1/IRE1 sensor of the unfolded protein response pathway
Length = 939
Score = 294 bits (752), Expect = 6e-79
Identities = 166/457 (36%), Positives = 249/457 (54%), Gaps = 80/457 (17%)
Query: 708 LSISSRVLGYGSSGTVVFQGKFQNRPVAVKRLLIDFYDIASKEIQLLSESDDHPNVIRYY 767
L +S++ + GS+GTVV +G ++ R VAVKRL+ +D+A KEI L SD H N++R+Y
Sbjct: 518 LFVSNKEIAKGSNGTVVLEGSYEGRLVAVKRLVQSHHDVAQKEILNLMASDKHSNIVRWY 577
Query: 768 FSESTEKFMYIAVELCSASLEDVIEGSKGLAKNVAVQKNIDPI--NVLFQ---------- 815
+ E F+YI++ELC+ SL D+I S L ++ +I I N +F+
Sbjct: 578 GVDQDEHFIYISLELCACSLNDLIYASSALLESPMASSSIHSIQINPIFENGKGVELWKE 637
Query: 816 --------------ITSGVNHLHSMKIVHRDLKPQNILIAPPKRYLSLHASKNKFRVLIS 861
I +G+ HLH + IVHRDLKPQN+LI + +S
Sbjct: 638 NGHPSPVLLKLMRDIVAGLVHLHDIGIVHRDLKPQNVLIV----------KNSSLCAKLS 687
Query: 862 DFGLCKKLEIDESSFRTNNFNNPTGTSGWRAPEIISGEVSLSESFAXXXXXXXXXXXXXX 921
D G+ K+L D S+ N+ + G+SGW+APE + E
Sbjct: 688 DMGISKRLPADTSALTRNSTGS--GSSGWQAPEQLRNE---------------------- 723
Query: 922 LDVNHMDLVTKKRLTRAVDIFSLGCIFYYVLSKGEHPFGDRILREANILKGDYRLDGIKK 981
R TRAVD+FSLGC+ ++ ++ G+HP+GD R+ N+L L I+
Sbjct: 724 ------------RQTRAVDLFSLGCVLFFCMTGGKHPYGDNYERDVNVLNDQKDLFLIES 771
Query: 982 SIQERSVCIEAADLIKSMLEQNPLLRPASDEILKHPLFWGVSKKLEFLLKVSDRFEVERR 1041
EA L+ +L +P LRP + +++ HPLFW +L FL SDR E+E R
Sbjct: 772 -------LPEAVHLLTGLLNPDPNLRPRAQDVMHHPLFWNSDMRLSFLRDASDRVELENR 824
Query: 1042 DPPSPLLLKLEEVSAKVITTGDWSMKFDAVFMENLGKYRKYKGEKLMDLLRALRNKYHHF 1101
+ S LL LE +A V G W K D++F++N+G+YR+YK + + DLLR +RNK +H+
Sbjct: 825 EEGSQLLAALESTAA-VTLNGRWDEKLDSIFLDNIGRYRRYKFDSIRDLLRVIRNKLNHY 883
Query: 1102 RDLPDELAEVMGPIPDGFYKYFIQRFPNLLMEIYYVV 1138
R+LP EL E++G +P+GF +YF RFP LL+++Y V+
Sbjct: 884 RELPKELQELLGSVPEGFERYFSSRFPKLLIQVYTVL 920
>At2g17520 [T] KOG1027 Serine/threonine protein kinase and endoribonuclease
ERN1/IRE1 sensor of the unfolded protein response pathway
Length = 393
Score = 270 bits (689), Expect = 1e-71
Identities = 158/445 (35%), Positives = 247/445 (55%), Gaps = 77/445 (17%)
Query: 708 LSISSRVLGYGSSGTVVFQGKFQNRPVAVKRLLIDFYDIASKEIQLLSESDDHPNVIRYY 767
L +SS+ + GS+GTVVF+G ++ RPVAVKRL+ +++A KEIQ L SD H N+IR+Y
Sbjct: 21 LFLSSKEIAKGSNGTVVFEGIYEGRPVAVKRLVRSHHEVAFKEIQNLIASDQHTNIIRWY 80
Query: 768 FSESTEKFMYIAVELCSASLEDVIEGSKGLAKNVAVQKNIDPINVLFQITSGVNHLHSMK 827
E + F+Y+++E C+ SL+D+I+ + ++ N T G
Sbjct: 81 GVEYDQDFVYLSLERCTCSLDDLIKSYLEFSMTKVLENN--------DSTEG-------- 124
Query: 828 IVHRDLKPQNILIAPPKRYLSLHASKNKFRVLISDFGLCKKLEIDESSFRTNNFNNPTGT 887
PQN+LI+ + ++L A +SD G+ K++ D SS + +G+
Sbjct: 125 -------PQNVLIS---KDMTLSAK-------LSDMGISKRMSRDMSSL--GHLATGSGS 165
Query: 888 SGWRAPEIISGEVSLSESFAXXXXXXXXXXXXXXLDVNHMDLVTKKRLTRAVDIFSLGCI 947
SGW+APE + + R TRAVD+FSLGC+
Sbjct: 166 SGWQAPEQL----------------------------------LQGRQTRAVDMFSLGCV 191
Query: 948 FYYVLSKGEHPFGDRILREANILKGDYRLDGIKKSIQERSVCIEAADLIKSMLEQNPLLR 1007
+Y ++ +HPFGD + R+ NI+K L ++ EA+DLI +L +P LR
Sbjct: 192 IFYTITGCKHPFGDDLERDVNIVKNKVDLFLVEH-------VPEASDLISRLLNPDPDLR 244
Query: 1008 PASDEILKHPLFWGVSKKLEFLLKVSDRFEVERRDPPSPLLLKLEEVSAKVITTGDWSMK 1067
P++ E+L HP+FW +L FL SDR E+E R+ S +L K E +A V G W K
Sbjct: 245 PSATEVLLHPMFWNSEMRLSFLRDASDRVELENREADSEIL-KAMESTAPVAIGGKWDEK 303
Query: 1068 FDAVFMENLGKYRKYKGEKLMDLLRALRNKYHHFRDLPDELAEVMGPIPDGFYKYFIQRF 1127
+ VF+ N+G+YR+YK + + DLLR +RNK +H R+LP E+ E++G +P+GF +YF RF
Sbjct: 304 LEPVFITNIGRYRRYKYDSIRDLLRVIRNKLNHHRELPPEIQELVGTVPEGFDEYFAVRF 363
Query: 1128 PNLLMEIYYVVDRNLKDDQVLSEFF 1152
P LL+E+Y V+ + ++++V ++F
Sbjct: 364 PKLLIEVYRVISLHCREEEVFRKYF 388
>At3g11870 [T] KOG1027 Serine/threonine protein kinase and endoribonuclease
ERN1/IRE1 sensor of the unfolded protein response pathway
Length = 554
Score = 176 bits (445), Expect = 2e-43
Identities = 145/510 (28%), Positives = 234/510 (45%), Gaps = 104/510 (20%)
Query: 692 PMLDFKEFEQE---GHL--KHLSISSRVLGYGSSGTVVFQGKFQNRP-VAVKRLLIDFYD 745
P L+ +++++ G + + L +S+ + YG +G VFQG + R VAVK L +
Sbjct: 99 PSLELRKYDENETPGKVVNRRLLVSTNEMKYGRNGYEVFQGVYGRRSSVAVKCLDLAHTT 158
Query: 746 IA--SKEIQLLSESDDHPNVIRYYFSESTEKFMYIAVELCSASLEDVIEGSKGLAKN--- 800
A EI DDH N+IR++ E + F YI +E SL+D+I+ S K
Sbjct: 159 EAFIQNEIDNHCLCDDHSNIIRFHGLEQDQSFAYICLEPWKCSLDDLIKLSVRRTKRDTQ 218
Query: 801 -VAVQKNIDPI--------------------NVLFQITSGVNHLHSMKIVHRDLKPQNIL 839
VA +++ + ++ + G+ HLH +K +HR+L PQN+L
Sbjct: 219 AVAPVDDLEKVMKRIKFWKEKGKPLPLTPMLKLMRDVVCGLAHLHKLKTIHRNLNPQNVL 278
Query: 840 IAPPKRYLSLHASKNKFRVLISDFGLCKKLEIDESSFRTNNFNNPTGTSGWRAPEIISGE 899
I L+ ISD L K L +SS++ + +G+SGW+APE ++ +
Sbjct: 279 IIVKDMTLTAK---------ISDMSLSKHLGGKKSSYK--HLATCSGSSGWQAPEQLNKD 327
Query: 900 VSLSESFAXXXXXXXXXXXXXXLDVNHMDLVTKKRLTRAVDIFSLGCIFYYVLSKGEHPF 959
E F D+F+ GC+ +Y + G HPF
Sbjct: 328 KKKKEDFPA-------------------------------DMFNFGCLLHYAVM-GTHPF 355
Query: 960 GDRILREANILKGDYRLDGIKKSIQERSVCIEAADLIKSMLEQNPLLRPASDEILKHPLF 1019
G R+ NI + K+ +EA +LI+ +L P LRP++ ++L HPLF
Sbjct: 356 GSPSERDTNIKTNN-------KTNLSLVTNLEAINLIEQLLNYKPDLRPSATQVLLHPLF 408
Query: 1020 WGVSKKLEFLLKVSDRFEVERRDPPSPLLLKLEEVSAKVI--TTGDWSMKFDAVF---ME 1074
W K+L FL + SDR E++ + L + A + + DW+ K F +E
Sbjct: 409 WDSEKRLFFLREASDRIELD-----ITMWGDLNKTIAPRVLGESKDWASKLGKTFITHIE 463
Query: 1075 NLGK----------YRKYKGEKLMDLLRALRNKYHHFRDLPDE--LAEVMGPIPDGFYKY 1122
NL + R YK L LLR +RN H R++ D+ + E++G +P+G +
Sbjct: 464 NLAQAQPGQESRQYNRSYKYWSLRHLLRLIRNILSHHREILDDPKIKEMVGKVPEGLDIF 523
Query: 1123 FIQRFPNLLMEIYYVVDRNLKDDQVLSEFF 1152
F RFPNL+MEIY + + K ++ ++F
Sbjct: 524 FTARFPNLMMEIYAFISMHCKGEEAFEKYF 553
>YPL153c [D] KOG0615 Serine/threonine protein kinase Chk2 and related proteins
Length = 821
Score = 83.2 bits (204), Expect = 2e-15
Identities = 85/325 (26%), Positives = 144/325 (44%), Gaps = 62/325 (19%)
Query: 703 GHLKHLSISSRVLGYGSSGTVV-----FQGKFQNRPVAVKRLLIDFYDIASKEIQLLSES 757
G K SI V+G G+ TV GK + KR +I D ++E+++L +
Sbjct: 192 GIFKDFSIIDEVVGQGAFATVKKAIERTTGKTFAVKIISKRKVIGNMDGVTRELEVLQKL 251
Query: 758 DDHPNVIRYY-FSESTEKFMYIAVELCSASLEDVIEGSKGLAKNVAVQKNIDPINVLFQI 816
+ HP ++R F E TE + + + L D + + ++ + + QI
Sbjct: 252 N-HPRIVRLKGFYEDTESYYMVMEFVSGGDLMDFVAAHGAVGEDAGRE-------ISRQI 303
Query: 817 TSGVNHLHSMKIVHRDLKPQNILIAPPKRYLSLHASKNKFRVLISDFGLCKKLEIDESSF 876
+ + ++HSM I HRDLKP NILI L V I+DFGL K++ + S
Sbjct: 304 LTAIKYIHSMGISHRDLKPDNILIEQDDPVL----------VKITDFGLA-KVQGNGSFM 352
Query: 877 RTNNFNNPTGTSGWRAPEIISGEVSLSESFAXXXXXXXXXXXXXXLDVNHMDLVTKKRLT 936
+T GT + APE+I G+ V+ + + +
Sbjct: 353 KTF-----CGTLAYVAPEVIRGK---------------------DTSVSPDEYEERNEYS 386
Query: 937 RAVDIFSLGCIFYYVLSKGEHPFG----DRILREANILKGDYRLDGIKKSIQERSVCIEA 992
VD++S+GC+ Y +L+ G PF D++ ++ I +G Y + +++ + EA
Sbjct: 387 SLVDMWSMGCLVYVILT-GHLPFSGSTQDQLYKQ--IGRGSYH----EGPLKDFRISEEA 439
Query: 993 ADLIKSMLEQNPLLRPASDEILKHP 1017
D I S+L+ +P R + + L HP
Sbjct: 440 RDFIDSLLQVDPNNRSTAAKALNHP 464
>7293666 [D] KOG0575 Polo-like serine/threonine protein kinase
Length = 576
Score = 82.4 bits (202), Expect = 4e-15
Identities = 79/303 (26%), Positives = 136/303 (44%), Gaps = 78/303 (25%)
Query: 724 VFQGKFQNRPVAVKRLLIDFYDIASKEIQLLSESDDHPNVIRY--YFSESTEKFMYIAVE 781
VF GK ++ + +K + + ++EI + S +HPN++++ YF +S +YI +E
Sbjct: 50 VFAGKIVSKKLMIKH---NQKEKTAQEITI-HRSLNHPNIVKFHNYFEDSQN--IYIVLE 103
Query: 782 LCSA-SLEDVIEGSKGLAKNVAVQKNIDPINVLFQITSGVNHLHSMKIVHRDLKPQNILI 840
LC S+ ++ + K + + + ++QI GV +LH +I+HRDLK N+ +
Sbjct: 104 LCKKRSMMELHKRRKSITE-------FECRYYIYQIIQGVKYLHDNRIIHRDLKLGNLFL 156
Query: 841 APPKRYLSLHASKNKFRVLISDFGLCKKLEIDESSFRTNNFNNPTGTSGWRAPEIISGEV 900
+ V I DFGL ++E + +T GT + APEI+
Sbjct: 157 ------------NDLLHVKIGDFGLATRIEYEGERKKT-----LCGTPNYIAPEIL---- 195
Query: 901 SLSESFAXXXXXXXXXXXXXXLDVNHMDLVTKKRLTRAVDIFSLGCIFYYVLSKGEHPFG 960
TKK + VDI+S+GC+ Y +L G+ PF
Sbjct: 196 ------------------------------TKKGHSFEVDIWSIGCVMYTLL-VGQPPFE 224
Query: 961 DRILRE--ANILKGDYRLDGIKKSIQERSVCIEAADLIKSMLEQNPLLRPASDEILKHPL 1018
+ L++ + I K +YR+ + AAD++ +ML+ NP RPA ++L
Sbjct: 225 TKTLKDTYSKIKKCEYRVPSYLRK--------PAADMVIAMLQPNPESRPAIGQLLNFEF 276
Query: 1019 FWG 1021
G
Sbjct: 277 LKG 279
>SPAC14C4.03 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-Hand protein
superfamily
Length = 445
Score = 81.3 bits (199), Expect = 8e-15
Identities = 83/339 (24%), Positives = 146/339 (42%), Gaps = 69/339 (20%)
Query: 698 EFEQEGHLKHLSISSRVLGYGSSGTVVFQGKFQNRPVAVKRLLIDFYDIASK------EI 751
+F E + +I+ R+LG G + + N +ID I++K E+
Sbjct: 149 DFHHEYAGERFNITQRLLGIGGFSRI-YMAMDNNTGGQYACKIIDKKKISTKRFFEDHEM 207
Query: 752 QLLSESDDHPNVIRYYFSESTEKFMYIAVELCSASLEDVIEGSK--GLAKNVAVQKNIDP 809
+L + D HPN+I+ ++E +I E+++ G + +
Sbjct: 208 TILRKLD-HPNIIKVNMEYNSETQFFI--------FEEMVTGGDLFSYLTKLGTVPEVTT 258
Query: 810 INVLFQITSGVNHLHSMKIVHRDLKPQNILIAPPKRYLSLHASKNKFRVLISDFGLCKKL 869
+ ++FQI G+ +LH I+HRDLK +NILIA +S FR++++DFG+ + +
Sbjct: 259 LFIMFQILQGLKYLHEQNIIHRDLKLENILIA--------SSSDTIFRIILTDFGVARCM 310
Query: 870 EIDESSFRTNNFNNPTGTSGWRAPEI--ISGEVSLSESFAXXXXXXXXXXXXXXLDVNHM 927
+ + + GT + APEI + G + +
Sbjct: 311 Q------KGKRLSTFVGTPEYTAPEIQRLKGR-------------------------SQV 339
Query: 928 DLVTKKRLTRAVDIFSLGCIFYYVLSKGEHPFGDRILREANILKGDYRLDGIKKSIQERS 987
+ + VD++SLG I + +LS F D + +E + D+R D + KS+
Sbjct: 340 EKENSSGYGKEVDLWSLGVIMFLLLSGNSPSFADGV-KEKQV---DFR-DPVWKSVSR-- 392
Query: 988 VCIEAADLIKSMLEQNPLLRPASDEILKHPLFWGVSKKL 1026
+A DLI ++L+ NP R + L HP F S +L
Sbjct: 393 ---QAKDLISNLLKTNPPDRFTVKQCLSHPWFARHSSRL 428
>ECU01g0630 [D] KOG0575 Polo-like serine/threonine protein kinase
Length = 488
Score = 81.3 bits (199), Expect = 8e-15
Identities = 112/450 (24%), Positives = 178/450 (38%), Gaps = 98/450 (21%)
Query: 702 EGHLKHLSISSRVLGYGSSGTVVFQGKFQNRPVAVKRLLIDFYDIASKEIQLLSESD--- 758
E H K++ ++LG G+ A+K ++ DI S+++ ES+
Sbjct: 35 EYHTKYML--KKLLGRGAYAQCYLAEIESGEQYAMK--VVRLKDIKSRKVHEKLESEIAI 90
Query: 759 ----DHPNVIRYYFSESTEKFMYIAVELCSASLEDVIEGSKGLAKNVAVQKNIDPINVLF 814
D+PNV++ Y S + +++++ +ELC D + G K V + +
Sbjct: 91 HSKLDNPNVVKMYRSFRSSEYVFMVLELCERGALDALLKRNGKLKERHVARFVK------ 144
Query: 815 QITSGVNHLH-SMKIVHRDLKPQNILIAPPKRYLSLHASKNKFRVLISDFGLCKKLEIDE 873
Q G+ +LH S+ +VHRDLK N+ + +KF V I DFGL ++ E
Sbjct: 145 QTVEGLIYLHNSVSVVHRDLKLGNLFL------------DSKFNVKIGDFGLSAVIKDGE 192
Query: 874 SSFRTNNFNNPTGTSGWRAPEIISGEVSLSESFAXXXXXXXXXXXXXXLDVNHMDLVTKK 933
GT + APE++ G+ S SF
Sbjct: 193 KKV------TMCGTPNYIAPEVLFGKAS-GHSF--------------------------- 218
Query: 934 RLTRAVDIFSLGCIFYYVLSKGEHPFGDRILREANILKGDYRLDGIKKSI--QERSVCIE 991
DI+SLG I Y +L G PF + + + Y++ + I + + E
Sbjct: 219 ----EADIWSLGVIIYTLL-VGVPPFQKKNVEDI------YKMIKLNNYIFPENCDLSSE 267
Query: 992 AADLIKSMLEQNPLLRPASDEILKHPLFWGVSKKLEFLLKVSDRFEVERRDPP------- 1044
A DLI +L NPL RP + IL H +SKK FL+K+ R +
Sbjct: 268 AIDLITQILNTNPLERPTLEHILSHKF---LSKKEHFLMKIYRNLMTNRTEEGVVDTDYV 324
Query: 1045 --SPLLLKLEEVSAKVITTGDWSMKFDAVFMENLGKYRK---YKGEKLMDLLRALRNKYH 1099
S + KL V V+ +G + + F L RK Y + R + H
Sbjct: 325 LFSIPVTKLRGV-GYVLKSGVYGIYFSDHRNLMLKPNRKSVIYLNSTIESGKRVFYKEEH 383
Query: 1100 HFRDLPDELAEVMGPIPDGFYKYFIQRFPN 1129
+P E+AE + +YFI+ F N
Sbjct: 384 LVEKIPAEIAESYKGL-----QYFIRTFDN 408
>SPCC18B5.11c [D] KOG0615 Serine/threonine protein kinase Chk2 and related proteins
Length = 460
Score = 80.5 bits (197), Expect = 1e-14
Identities = 84/304 (27%), Positives = 127/304 (41%), Gaps = 74/304 (24%)
Query: 745 DIASKEIQLLSESDDHPNVIRYYFSESTEKFMYIAVELCSAS-LEDVIEGSKGLAKNVAV 803
++ +EI +L +S HP V++ + + ++I +E L D + +A
Sbjct: 214 EMFQREIDIL-KSLHHPGVVQCHEIFENDDELFIVMEYVEGGDLMDFL-----IANGSID 267
Query: 804 QKNIDPINVLFQITSGVNHLHSMKIVHRDLKPQNILIAPPKRYLSLHASKNKFRVLISDF 863
+++ P+ L Q+ + HLH + HRD+KP+NILI N F + ISDF
Sbjct: 268 EQDCKPL--LKQLLETLLHLHKQGVTHRDIKPENILIT------------NDFHLKISDF 313
Query: 864 GLCKKLEIDESSFRTNNFNNPTGTSGWRAPEIISGEVSLSESFAXXXXXXXXXXXXXXLD 923
GL K + + T GT G+ APE++ + LD
Sbjct: 314 GLAKVIHGTGTFLETF-----CGTMGYLAPEVLKSK-------------------NVNLD 349
Query: 924 VNHMDLVTKKRLTRAVDIFSLGCIFYYVLSKGEHPFGDRILREA--NILKGDYRLDGIKK 981
+ D VDI+SLGC+ Y +L+ PF + I KG Y ++
Sbjct: 350 GGYDD---------KVDIWSLGCVLYVMLT-ASIPFASSSQAKCIELISKGAYPIE---- 395
Query: 982 SIQERSVCIEAADLIKSMLEQNPLLRPASDEILKHPLFWGVSKKLEFLLKVSDRFEVERR 1041
+ E + E DLI MLE NP R + E L+HP F+ VS E R
Sbjct: 396 PLLENEISEEGIDLINRMLEINPEKRISESEALQHPWFYTVSTH-------------EHR 442
Query: 1042 DPPS 1045
PPS
Sbjct: 443 TPPS 446
>SPBC1D7.05c [T] KOG0198 MEKK and related serine/threonine protein kinases
Length = 362
Score = 77.4 bits (189), Expect = 1e-13
Identities = 80/321 (24%), Positives = 129/321 (39%), Gaps = 72/321 (22%)
Query: 710 ISSRVLGYGSSGTVVF-QGKFQNRPVAVKRLLID-----------FYDIASKEIQLLSES 757
I ++G GS G V +AVK++++D D + EI LL E
Sbjct: 98 IRGALIGSGSFGQVYLGMNASSGELMAVKQVILDSVSESKDRHAKLLDALAGEIALLQEL 157
Query: 758 DDHPNVIRYYFSESTEKFMYIAVELCSASLEDVIEGSKGLAKNVAVQKNIDPINVLFQIT 817
H ++++Y S + I +E + G + V+ N + Q
Sbjct: 158 S-HEHIVQYLGSNLNSDHLNIFLEYVPGGSVAGLLTMYGSFEETLVK------NFIKQTL 210
Query: 818 SGVNHLHSMKIVHRDLKPQNILIAPPKRYLSLHASKNKFRVLISDFGLCKKLEIDESSFR 877
G+ +LHS IVHRD+K NIL+ NK ++ ISDFG+ KKLE++ +S +
Sbjct: 211 KGLEYLHSRGIVHRDIKGANILV------------DNKGKIKISDFGISKKLELNSTSTK 258
Query: 878 TNNFN-NPTGTSGWRAPEIISGEVSLSESFAXXXXXXXXXXXXXXLDVNHMDLVTKKRLT 936
T + G+S W APE++ + T
Sbjct: 259 TGGARPSFQGSSFWMAPEVVKQTMH----------------------------------T 284
Query: 937 RAVDIFSLGCIFYYVLSKGEHPFGDRILREANILKGDYRLDGIKKSIQERSVCIEAADLI 996
DI+SLGC+ +L+ +HP+ + +A G+ L +I A D +
Sbjct: 285 EKTDIWSLGCLVIEMLT-SKHPYPNCDQMQAIFRIGENILPEFPSNISS-----SAIDFL 338
Query: 997 KSMLEQNPLLRPASDEILKHP 1017
+ + LRP + E+L HP
Sbjct: 339 EKTFAIDCNLRPTASELLSHP 359
>Hs4557439 [R] KOG0594 Protein kinase PCTAIRE and related kinases
Length = 305
Score = 77.0 bits (188), Expect = 2e-13
Identities = 90/336 (26%), Positives = 141/336 (41%), Gaps = 90/336 (26%)
Query: 715 LGYGSSGTVVFQGKFQNRP----VAVKRLLIDFY-----DIASKEIQLLSESDDHPNVIR 765
+G G+ G V K +NR VA+K++ +D A +EI LL E HPN++R
Sbjct: 10 IGEGTYGVVY---KAKNRETGQLVALKKIRLDLEMEGVPSTAIREISLLKELK-HPNIVR 65
Query: 766 YYFSESTEKFMYIAVELCSASLEDVIEGSKGLAKNVAVQKNIDPINVLFQITSGVNHLHS 825
E+ +Y+ E S L+ ++ + G + + K+ LFQ+ GV+ HS
Sbjct: 66 LLDVVHNERKLYLVFEFLSQDLKKYMDSTPGSELPLHLIKSY-----LFQLLQGVSFCHS 120
Query: 826 MKIVHRDLKPQNILIAPPKRYLSLHASKNKFRVLISDFGLCKKLEIDESSFRTNNFNNPT 885
+++HRDLKPQN+LI L A K ++DFGL + + + +
Sbjct: 121 HRVIHRDLKPQNLLIN------ELGAIK------LADFGLARAFGVP-----LRTYTHEV 163
Query: 886 GTSGWRAPEIISGEVSLSESFAXXXXXXXXXXXXXXLDVNHMDLVTKKRLTRAVDIFSLG 945
T +RAPEI+ G K T AVDI+S+G
Sbjct: 164 VTLWYRAPEILLG---------------------------------SKFYTTAVDIWSIG 190
Query: 946 CIFYYVLSKGEHPFGD-------RILR-----EANILKGDYRLDGIK--------KSIQE 985
CIF ++++ GD RI R + G +L K K ++E
Sbjct: 191 CIFAEMVTRKALFPGDSEIDQLFRIFRMLGTPSEDTWPGVTQLPDYKGSFPKWTRKGLEE 250
Query: 986 --RSVCIEAADLIKSMLEQNPLLRPASDEILKHPLF 1019
++ E DL+ +L+ +P R + L HP F
Sbjct: 251 IVPNLEPEGRDLLMQLLQYDPSQRITAKTALAHPYF 286
>Hs16936528 [R] KOG0594 Protein kinase PCTAIRE and related kinases
Length = 298
Score = 75.5 bits (184), Expect = 5e-13
Identities = 87/343 (25%), Positives = 141/343 (40%), Gaps = 84/343 (24%)
Query: 715 LGYGSSGTVV-FQGKFQNRPVAVKRLLIDFY-----DIASKEIQLLSESDDHPNVIRYYF 768
+G G+ G V + K VA+K++ +D A +EI LL E + HPN+++
Sbjct: 10 IGEGTYGVVYKARNKLTGEVVALKKIRLDTETEGVPSTAIREISLLKELN-HPNIVKLLD 68
Query: 769 SESTEKFMYIAVELCSASLEDVIEGSKGLAKNVAVQKNIDPINVLFQITSGVNHLHSMKI 828
TE +Y+ E L+ ++ S + + K+ LFQ+ G+ HS ++
Sbjct: 69 VIHTENKLYLVFEFLHQDLKKFMDASALTGIPLPLIKSY-----LFQLLQGLAFCHSHRV 123
Query: 829 VHRDLKPQNILIAPPKRYLSLHASKNKFRVLISDFGLCKKLEIDESSFRTNNFNNPTGTS 888
+HRDLKPQN+LI + + ++DFGL + + + + T
Sbjct: 124 LHRDLKPQNLLI------------NTEGAIKLADFGLARAFGVP-----VRTYTHEVVTL 166
Query: 889 GWRAPEIISGEVSLSESFAXXXXXXXXXXXXXXLDVNHMDLVTKKRLTRAVDIFSLGCIF 948
+RAPEI+ G K + AVDI+SLGCIF
Sbjct: 167 WYRAPEILLG---------------------------------CKYYSTAVDIWSLGCIF 193
Query: 949 YYVLSKGEHPFGD-------RILR-----EANILKG-----DYRLDGIKKSIQERSVCIE 991
++++ GD RI R + + G DY+ K + Q+ S +
Sbjct: 194 AEMVTRRALFPGDSEIDQLFRIFRTLGTPDEVVWPGVTSMPDYKPSFPKWARQDFSKVVP 253
Query: 992 AAD-----LIKSMLEQNPLLRPASDEILKHPLFWGVSKKLEFL 1029
D L+ ML +P R ++ L HP F V+K + L
Sbjct: 254 PLDEDGRSLLSQMLHYDPNKRISAKAALAHPFFQDVTKPVPHL 296
>Hs14141724 [T] KOG0033 Ca2+/calmodulin-dependent protein kinase EF-Hand protein
superfamily
Length = 499
Score = 75.5 bits (184), Expect = 5e-13
Identities = 74/265 (27%), Positives = 112/265 (41%), Gaps = 71/265 (26%)
Query: 760 HPNVIRYYFSESTEKFMYIAVELCSAS--LEDVIEGSKGLAKNVAVQKNIDPINVLFQIT 817
HPN++R + S S E F Y+ +L + ED++ D + + QI
Sbjct: 70 HPNIVRLHDSISEEGFHYLVFDLVTGGELFEDIVARE--------YYSEADASHCIQQIL 121
Query: 818 SGVNHLHSMKIVHRDLKPQNILIAPPKRYLSLHASKNK-FRVLISDFGLCKKLEIDESSF 876
VNH H IVHRDLKP+N+L+ ASK+K V ++DFGL +++ D+ +
Sbjct: 122 ESVNHCHLNGIVHRDLKPENLLL----------ASKSKGAAVKLADFGLAIEVQGDQQA- 170
Query: 877 RTNNFNNPTGTSGWRAPEIISGEVSLSESFAXXXXXXXXXXXXXXLDVNHMDLVTKKRLT 936
+ GT G+ +PE++ K
Sbjct: 171 ----WFGFAGTPGYLSPEVL----------------------------------RKDPYG 192
Query: 937 RAVDIFSLGCIFYYVLSKGEHPFGD----RILREANILKGDYRLDGIKKSIQERSVCIEA 992
+ VD+++ G I Y+L G PF D R+ ++ D+ S + +V EA
Sbjct: 193 KPVDMWACGVIL-YILLVGYPPFWDEDQHRLYQQIKAGAYDF------PSPEWDTVTPEA 245
Query: 993 ADLIKSMLEQNPLLRPASDEILKHP 1017
DLI ML NP R + E LKHP
Sbjct: 246 KDLINKMLTINPAKRITASEALKHP 270
>Hs4502553 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-Hand protein
superfamily
Length = 370
Score = 74.3 bits (181), Expect = 1e-12
Identities = 84/317 (26%), Positives = 138/317 (43%), Gaps = 72/317 (22%)
Query: 714 VLGYGSSGTVVF-QGKFQNRPVAVKRLLIDFYD----IASKEIQLLSESDDHPNVIRYYF 768
VLG G+ V+ + K + VA+K + + + EI +L + HPN++
Sbjct: 25 VLGTGAFSEVILAEDKRTQKLVAIKCIAKEALEGKEGSMENEIAVLHKIK-HPNIVALDD 83
Query: 769 SESTEKFMYIAVELCSAS--LEDVIEGSKGLAKNVAVQKNIDPINVLFQITSGVNHLHSM 826
+ +Y+ ++L S + ++E K ++ D ++FQ+ V +LH +
Sbjct: 84 IYESGGHLYLIMQLVSGGELFDRIVE------KGFYTER--DASRLIFQVLDAVKYLHDL 135
Query: 827 KIVHRDLKPQNILIAPPKRYLSLHASKNKFRVLISDFGLCKKLEIDESSFRTNNFNNPTG 886
IVHRDLKP+N+L Y SL +++ISDFGL K+E S T G
Sbjct: 136 GIVHRDLKPENLL------YYSLDEDS---KIMISDFGL-SKMEDPGSVLST-----ACG 180
Query: 887 TSGWRAPEIISGEVSLSESFAXXXXXXXXXXXXXXLDVNHMDLVTKKRLTRAVDIFSLGC 946
T G+ APE+++ +K ++AVD +S+G
Sbjct: 181 TPGYVAPEVLA----------------------------------QKPYSKAVDCWSIGV 206
Query: 947 IFYYVLSKGEHPFGDRILRE--ANILKGDYRLDGIKKSIQERSVCIEAADLIKSMLEQNP 1004
I Y +L G PF D + ILK +Y D S + A D I+ ++E++P
Sbjct: 207 IAYILLC-GYPPFYDENDAKLFEQILKAEYEFD----SPYWDDISDSAKDFIRHLMEKDP 261
Query: 1005 LLRPASDEILKHPLFWG 1021
R ++ L+HP G
Sbjct: 262 EKRFTCEQALQHPWIAG 278
>At3g48750 [R] KOG0594 Protein kinase PCTAIRE and related kinases
Length = 294
Score = 74.3 bits (181), Expect = 1e-12
Identities = 66/246 (26%), Positives = 110/246 (43%), Gaps = 61/246 (24%)
Query: 715 LGYGSSGTVV-FQGKFQNRPVAVKRLLIDFYD-----IASKEIQLLSESDDHPNVIRYYF 768
+G G+ G V + K N +A+K++ ++ D A +EI LL E H N+++Y
Sbjct: 10 IGEGTYGVVYKARDKVTNETIALKKIRLEQEDEGVPSTAIREISLLKEMQ-HSNIVKYDD 68
Query: 769 SESTEKFMYIAVELCSASLEDVIEGSKGLAKNVAVQKNIDPINVLFQITSGVNHLHSMKI 828
+EK +Y+ E L+ ++ + +K++ + K L+QI G+ + HS ++
Sbjct: 69 VVHSEKRLYLVFEYLDLDLKKHMDSTPDFSKDLHMIKTY-----LYQILRGIAYCHSHRV 123
Query: 829 VHRDLKPQNILIAPPKRYLSLHASKNKFRVLISDFGLCKKLEIDESSFRTNNFNNPTGTS 888
+HRDLKPQN+LI +R SL ++DFGL + I F + T
Sbjct: 124 LHRDLKPQNLLI--DRRTNSLK---------LADFGLARAFGIP-----VRTFTHEVVTL 167
Query: 889 GWRAPEIISGEVSLSESFAXXXXXXXXXXXXXXLDVNHMDLVTKKRLTRAVDIFSLGCIF 948
+RAPEI+ G + VDI+S+GCIF
Sbjct: 168 WYRAPEILLG---------------------------------SHHYSTPVDIWSVGCIF 194
Query: 949 YYVLSK 954
++S+
Sbjct: 195 AEMISQ 200
>YOR351c [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-Hand protein
superfamily
Length = 497
Score = 73.9 bits (180), Expect = 1e-12
Identities = 101/404 (25%), Positives = 169/404 (41%), Gaps = 87/404 (21%)
Query: 688 DDDGPMLDFKEFEQEGHLKHLS---ISSRVLGYGSSGTVVFQGKFQNRP----------- 733
DD LD K +Q G L+ + I++R++G G+ G V+ + R
Sbjct: 138 DDLQSSLDPKLLDQMGFLREVDQWEITNRIVGNGTFGHVLITHNSKERDEDVCYHPENYA 197
Query: 734 VAVKRLLIDFYDIASKEIQLLSESDDHPNVIRYYFSE-STEKFMYIAVELCSASLEDVIE 792
V + +L + +D KE ++L D HPN+I+ Y + +YI +D+I
Sbjct: 198 VKIIKLKPNKFD---KEARILLRLD-HPNIIKVYHTFCDRNNHLYI--------FQDLIP 245
Query: 793 GS---KGLAKN--VAVQKNIDPINVLFQITSGVNHLHSMKIVHRDLKPQNILIAPPKRYL 847
G LAK + + + ++FQI +N+LH IVHRDLK NIL+ P+
Sbjct: 246 GGDLFSYLAKGDCLTSMSETESLLIVFQILQALNYLHDQDIVHRDLKLDNILLCTPEPCT 305
Query: 848 SLHASKNKFRVLISDFGLCKKLEIDESSFRTNNFNNPTGTSGWRAPEIISGEVSLSESFA 907
R++++DFG+ K L ++ T GT + APE+ F
Sbjct: 306 ---------RIVLADFGIAKDLNSNKERMHT-----VVGTPEYCAPEV---------GFR 342
Query: 908 XXXXXXXXXXXXXXLDVNHMDLVTKKRLTRAVDIFSLGCIFYYVLSKGEHPFGD----RI 963
L+ D D++SLG I + +L+ +GD I
Sbjct: 343 ANRKAYQSFSRAATLEQRGYD--------SKCDLWSLGVITHIMLTGISPFYGDGSERSI 394
Query: 964 LREANILKGDYRLDGIKKSIQERSVCIEAADLIKSMLEQNPLLRPASDEILKHPLFWGVS 1023
++ A I K +++L Q V A +K +L+ + + R S + LKH W ++
Sbjct: 395 IQNAKIGKLNFKLK------QWDIVSDNAKSFVKDLLQTDVVKRLNSKQGLKH--IW-IA 445
Query: 1024 KKLEFLLKVSDRFEVERRDPPSPLLLKLEEVSAKVITTGDWSMK 1067
K L L ++ + + + P KLE +++ DW K
Sbjct: 446 KHLSQLERLYYKKILCNNEGP-----KLESINS------DWKRK 478
>SPAC890.03 [T] KOG0583 Serine/threonine protein kinase
Length = 672
Score = 73.2 bits (178), Expect = 2e-12
Identities = 83/314 (26%), Positives = 126/314 (39%), Gaps = 78/314 (24%)
Query: 714 VLGYGSSGTVVFQGKF-QNRPVAVKRLLIDFYDIASKEI----QLLSESDDHPNVIRYYF 768
V+G GS G V N V +K I ++EI +LL HPN+ R Y
Sbjct: 36 VVGEGSFGKVYLAAHLLTNTKVVLKSSCRKQAIILAREIHHHRRLL-----HPNITRLYE 90
Query: 769 SESTEKFMYIAVELC-SASLEDVIEGSKGLAKNVAVQKNIDPINVLFQITSGVNHLHSMK 827
TE +Y+A+E C + L D + K L + + +++Q+ + +LH
Sbjct: 91 VVCTEDRIYLAMEYCPNGELYDWVAREKRLDEKTTCR-------IMWQLCCAIQYLHRQG 143
Query: 828 IVHRDLKPQNILIAPPKRYLSLHASKNKFRVLISDFGLCKKLEIDESSFRTNNFNNPTGT 887
VHRDLK +NI + + V + DFG + D R N GT
Sbjct: 144 CVHRDLKLENIFL------------DKAYNVKLGDFGFSR----DSDCSRRTFMNTRCGT 187
Query: 888 SGWRAPEIISGEVSLSESFAXXXXXXXXXXXXXXLDVNHMDLVTKKRLTRAVDIFSLGCI 947
+ APE++ G K + VDI+SLG I
Sbjct: 188 VAYCAPELVQGH---------------------------------KYIGECVDIWSLGII 214
Query: 948 FYYVLSKGEHPF--GDRILREANILKGDYRLDGIKKSIQERSVCIEAADLIKSMLEQNPL 1005
Y +L G PF D L E I+ +++ + S + L+KS+L ++
Sbjct: 215 MYALLI-GRLPFDEDDVSLTEQKIIN---ECPQYPETLSKNS-----SSLLKSLLCKDYR 265
Query: 1006 LRPASDEILKHPLF 1019
LRP+ D+I+ HP F
Sbjct: 266 LRPSIDQIISHPYF 279
>Hs4759050 [T] KOG0603 Ribosomal protein S6 kinase
Length = 740
Score = 73.2 bits (178), Expect = 2e-12
Identities = 78/278 (28%), Positives = 112/278 (40%), Gaps = 69/278 (24%)
Query: 748 SKEIQLLSESDDHPNVIRYYFSESTEKFMYIAVELCSAS-LEDVIEGSKGLAKNVAVQKN 806
++EI++L HPN+I K++Y+ EL L D I K ++ A
Sbjct: 461 TEEIEILLRYGQHPNIITLKDVYDDGKYVYVVTELMKGGELLDKILRQKFFSEREASA-- 518
Query: 807 IDPINVLFQITSGVNHLHSMKIVHRDLKPQNILIAPPKRYLSLHASKNKFRVLISDFGLC 866
VLF IT V +LH+ +VHRDLKP NIL + S N + I DFG
Sbjct: 519 -----VLFTITKTVEYLHAQGVVHRDLKPSNILY--------VDESGNPESIRICDFGFA 565
Query: 867 KKLEIDESSFRTNNFNNPTGTSGWRAPEIISGEVSLSESFAXXXXXXXXXXXXXXLDVNH 926
K+L + T P T+ + APE++
Sbjct: 566 KQLRAENGLLMT-----PCYTANFVAPEVLK----------------------------- 591
Query: 927 MDLVTKKRLTRAVDIFSLGCIFYYVLSKGEHPFG-------DRILREANILKGDYRLDGI 979
++ A DI+SLG + Y +L+ G PF + IL A I G + L G
Sbjct: 592 -----RQGYDAACDIWSLGVLLYTMLT-GYTPFANGPDDTPEEIL--ARIGSGKFSLSG- 642
Query: 980 KKSIQERSVCIEAADLIKSMLEQNPLLRPASDEILKHP 1017
SV A DL+ ML +P R + +L+HP
Sbjct: 643 ---GYWNSVSDTAKDLVSKMLHVDPHQRLTAALVLRHP 677
>Hs19923570 [T] KOG0603 Ribosomal protein S6 kinase
Length = 733
Score = 73.2 bits (178), Expect = 2e-12
Identities = 81/286 (28%), Positives = 118/286 (40%), Gaps = 71/286 (24%)
Query: 748 SKEIQLLSESDDHPNVIRYYFSESTEKFMYIAVELC-SASLEDVIEGSKGLAKNVAVQKN 806
S+EI++L HPN+I KF+Y+ +EL L D I + ++ A
Sbjct: 454 SEEIEILLRYGQHPNIITLKDVYDDGKFVYLVMELMRGGELLDRILRQRYFSEREAS--- 510
Query: 807 IDPINVLFQITSGVNHLHSMKIVHRDLKPQNILIAPPKRYLSLHASKNKFRVLISDFGLC 866
+VL IT +++LHS +VHRDLKP NIL Y S RV DFG
Sbjct: 511 ----DVLCTITKTMDYLHSQGVVHRDLKPSNIL------YRDESGSPESIRV--CDFGFA 558
Query: 867 KKLEIDESSFRTNNFNNPTGTSGWRAPEIISGEVSLSESFAXXXXXXXXXXXXXXLDVNH 926
K+L T P T+ + APE++
Sbjct: 559 KQLRAGNGLLMT-----PCYTANFVAPEVLK----------------------------- 584
Query: 927 MDLVTKKRLTRAVDIFSLGCIFYYVLSKGEHPFG-------DRILREANILKGDYRLDGI 979
++ A DI+SLG + Y +L+ G PF + IL A I G Y L G
Sbjct: 585 -----RQGYDAACDIWSLGILLYTMLA-GFTPFANGPDDTPEEIL--ARIGSGKYALSGG 636
Query: 980 KKSIQERSVCIEAADLIKSMLEQNPLLRPASDEILKHPLFWGVSKK 1025
S+ A D++ ML +P R + ++LKHP W V+++
Sbjct: 637 NWD----SISDAAKDVVSKMLHVDPHQRLTAMQVLKHP--WVVNRE 676
Score = 57.8 bits (138), Expect = 1e-07
Identities = 81/352 (23%), Positives = 144/352 (40%), Gaps = 98/352 (27%)
Query: 700 EQEGHLKHLSISS-----------------RVLGYGSSGTVVFQGKFQNRPVA------- 735
E+EG +K + IS +VLG GS G V K +
Sbjct: 33 EEEGVVKEIDISHHVKEGFEKADPSQFELLKVLGQGSYGKVFLVRKVKGSDAGQLYAMKV 92
Query: 736 VKRLLIDFYD-IASKEIQLLSESDDHPNVIRYYFSESTEKFMYIAVELCSASLEDVIEGS 794
+K+ + D + SK + + +HP +++ +++ TE +Y+ ++ +
Sbjct: 93 LKKATLKVRDRVRSKMERDILAEVNHPFIVKLHYAFQTEGKLYLILDFLRGG-----DLF 147
Query: 795 KGLAKNVAVQKNIDPINVLFQITSGVNHLHSMKIVHRDLKPQNILIAPPKRYLSLHASKN 854
L+K V + D L ++ ++HLHS+ I++RDLKP+NIL+
Sbjct: 148 TRLSKEVMFTEE-DVKFYLAELALALDHLHSLGIIYRDLKPENILL------------DE 194
Query: 855 KFRVLISDFGLCKKLEIDESSFRTNNFNNPTGTSGWRAPEIISGEVSLSESFAXXXXXXX 914
+ + I+DFGL K E + R +F GT + APE+
Sbjct: 195 EGHIKITDFGLSK--EAIDHDKRAYSF---CGTIEYMAPEV------------------- 230
Query: 915 XXXXXXXLDVNHMDLVTKKRLTRAVDIFSLGCIFYYVLSKGEHPFGDRILRE--ANILKG 972
V ++ T++ D +S G + + +L+ G PF + +E A ILK
Sbjct: 231 ---------------VNRRGHTQSADWWSFGVLMFEMLT-GSLPFQGKDRKETMALILKA 274
Query: 973 DYRLDGIKKSIQERSVCIEAADLIKSMLEQNPLLRPAS-----DEILKHPLF 1019
K + + EA L++++ ++NP R + +EI +HP F
Sbjct: 275 --------KLGMPQFLSGEAQSLLRALFKRNPCNRLGAGIDGVEEIKRHPFF 318
>CE27297 [D] KOG0615 Serine/threonine protein kinase Chk2 and related proteins
Length = 476
Score = 73.2 bits (178), Expect = 2e-12
Identities = 78/328 (23%), Positives = 129/328 (38%), Gaps = 82/328 (25%)
Query: 706 KHLSISSRVLGYGSSGTVVFQGKFQNRPV-AVKRLLIDFYDIASK----------EIQLL 754
K ++S LG G G V+ K +R V A+K+L F S+ E++++
Sbjct: 167 KKYHVTSHSLGKGGFGKVLLGYKKSDRSVVAIKQLNTQFSTRCSRAIAKTRDIRNEVEVM 226
Query: 755 SESDDHPNVIRYYFSESTEKFMYIAVELCS-----ASLEDVIEGSKGLAKNVAVQKNIDP 809
+ HPN++ Y + K+ Y+ +E + + D GL +++
Sbjct: 227 KKLS-HPNIVAIYDWITVAKYSYMVIEYVGGGEFFSKVVDSKYNRMGLGESLGKY----- 280
Query: 810 INVLFQITSGVNHLHSMKIVHRDLKPQNILIAPPKRYLSLHASKNKFRVLISDFGLCKKL 869
FQ+ + +LHS+ I HRD+KP+NIL + L ++DFG+ K
Sbjct: 281 --FAFQLIDAILYLHSVGICHRDIKPENILCSDKAERCILK---------LTDFGMAKN- 328
Query: 870 EIDESSFRTNNFNNPTGTSGWRAPEIISGEVSLSESFAXXXXXXXXXXXXXXLDVNHMDL 929
N GT + APEI++ E
Sbjct: 329 -------SVNRMKTRCGTPSYNAPEIVANE------------------------------ 351
Query: 930 VTKKRLTRAVDIFSLGCIFYYVLSKGEHPFGDR---ILREANILKGDYRLDGIKKSIQER 986
T VDI+SLGC+ + S G PF + + + +L G Q R
Sbjct: 352 --GVEYTPKVDIWSLGCVLFITFS-GYPPFSEEYTDMTMDEQVLTGRLIFHA-----QWR 403
Query: 987 SVCIEAADLIKSMLEQNPLLRPASDEIL 1014
+ +E ++IK ML P RP++ E++
Sbjct: 404 RITVETQNMIKWMLTVEPSNRPSAVELM 431
>7304358 [T] KOG0033 Ca2+/calmodulin-dependent protein kinase EF-Hand protein
superfamily
Length = 493
Score = 72.8 bits (177), Expect = 3e-12
Identities = 72/265 (27%), Positives = 110/265 (41%), Gaps = 71/265 (26%)
Query: 760 HPNVIRYYFSESTEKFMYIAVELCSAS--LEDVIEGSKGLAKNVAVQKNIDPINVLFQIT 817
HPN++R + S E + Y+ +L + ED++ D + + QI
Sbjct: 70 HPNIVRLHDSIQEENYHYLVFDLVTGGELFEDIVARE--------FYSEADASHCIQQIL 121
Query: 818 SGVNHLHSMKIVHRDLKPQNILIAPPKRYLSLHASKNK-FRVLISDFGLCKKLEIDESSF 876
VNH H +VHRDLKP+N+L+ ASK K V ++DFGL +++ D +
Sbjct: 122 ESVNHCHQNGVVHRDLKPENLLL----------ASKAKGAAVKLADFGLAIEVQGDHQA- 170
Query: 877 RTNNFNNPTGTSGWRAPEIISGEVSLSESFAXXXXXXXXXXXXXXLDVNHMDLVTKKRLT 936
+ GT G+ +PE++ K+
Sbjct: 171 ----WFGFAGTPGYLSPEVLK----------------------------------KEPYG 192
Query: 937 RAVDIFSLGCIFYYVLSKGEHPFGD----RILREANILKGDYRLDGIKKSIQERSVCIEA 992
++VDI++ G I Y+L G PF D R+ + DY S + +V EA
Sbjct: 193 KSVDIWACGVIL-YILLVGYPPFWDEDQHRLYSQIKAGAYDY------PSPEWDTVTPEA 245
Query: 993 ADLIKSMLEQNPLLRPASDEILKHP 1017
+LI ML NP R + E LKHP
Sbjct: 246 KNLINQMLTVNPNKRITAAEALKHP 270
>SPAC1F5.09c [T] KOG0578 p21-activated serine/threonine protein kinase
Length = 589
Score = 72.4 bits (176), Expect = 4e-12
Identities = 59/195 (30%), Positives = 92/195 (46%), Gaps = 41/195 (21%)
Query: 715 LGYGSSGTVVFQ--------GKFQNRPVAVKRLLIDFY---DIASKEIQLLSESDDHPNV 763
LG G+SG+V G F + VA+K + + ++ EI ++ ES HPN+
Sbjct: 315 LGQGASGSVYLAKVVGGKQLGIFDS--VAIKSIDLQCQTRKELILNEITVMRESI-HPNI 371
Query: 764 IRYYFSEST-EKFMYIAVELCSA-SLEDVIEGSKGLAKNVAVQKNIDPINVLFQITSGVN 821
+ Y S E+ +++ +E +A SL D+IE SK +A + + G+
Sbjct: 372 VTYLDSFLVRERHLWVVMEYMNAGSLTDIIEKSKLTEAQIA--------RICLETCKGIQ 423
Query: 822 HLHSMKIVHRDLKPQNILIAPPKRYLSLHASKNKFRVLISDFGLCKKLEIDESSFRTNNF 881
HLH+ I+HRD+K N+L+ N + I+DFG C +L S RTN
Sbjct: 424 HLHARNIIHRDIKSDNVLL------------DNSGNIKITDFGFCARL-----SNRTNKR 466
Query: 882 NNPTGTSGWRAPEII 896
GT W APE++
Sbjct: 467 VTMVGTPYWMAPEVV 481
>Hs14776113 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-Hand protein
superfamily
Length = 424
Score = 72.4 bits (176), Expect = 4e-12
Identities = 86/320 (26%), Positives = 141/320 (43%), Gaps = 75/320 (23%)
Query: 714 VLGYGSSGTVV-FQGKFQNRPVAVKRLLIDFYD---IASKEIQLLSESDDHPNVIRYYFS 769
++G GS VV + + +P A+K + + + + E+++L H N+I+
Sbjct: 103 LIGRGSFSRVVRVEHRATRQPYAIKMIETKYREGREVCESELRVLRRVR-HANIIQLVEV 161
Query: 770 ESTEKFMYIAVELCSAS-LEDVIEGSKGLAKNVAVQKNIDPINVLFQITSGVNHLHSMKI 828
T++ +Y+ +EL + L D I +AK ++ D VL + GV +LH++ I
Sbjct: 162 FETQERVYMVMELATGGELFDRI-----IAKGSFTER--DATRVLQMVLDGVRYLHALGI 214
Query: 829 VHRDLKPQNILIAPPKRYLSLHASKNKFRVLISDFGLCK-KLEIDESSFRTNNFNNPTGT 887
HRDLKP+N+L P +++I+DFGL + + D+ +T GT
Sbjct: 215 THRDLKPENLLYYHP---------GTDSKIIITDFGLASARKKGDDCLMKTT-----CGT 260
Query: 888 SGWRAPEIISGEVSLSESFAXXXXXXXXXXXXXXLDVNHMDLVTKKRLTRAVDIFSLGCI 947
+ APE++ +K T +VD+++LG I
Sbjct: 261 PEYIAPEVL----------------------------------VRKPYTNSVDMWALGVI 286
Query: 948 FYYVLSKGEHPFGD----RILREANILKGDYRLDGIKKSIQERSVCIEAADLIKSMLEQN 1003
Y +LS G PF D R+ R+ IL+G Y G SV A D I +L +
Sbjct: 287 AYILLS-GTMPFEDDNRTRLYRQ--ILRGKYSYSGEPWP----SVSNLAKDFIDRLLTVD 339
Query: 1004 PLLRPASDEILKHPLFWGVS 1023
P R + + L+HP W VS
Sbjct: 340 PGARMTALQALRHP--WVVS 357
>CE29020 [T] KOG0660 Mitogen-activated protein kinase
Length = 470
Score = 72.4 bits (176), Expect = 4e-12
Identities = 66/249 (26%), Positives = 103/249 (40%), Gaps = 63/249 (25%)
Query: 715 LGYGSSGTV-VFQGKFQNRPVAVKRLLIDFYDIAS-----KEIQLLSESDDHPNVIRYY- 767
LG G+ G V K VA+K++ F + +E+ L E HPNVI+ Y
Sbjct: 19 LGKGAYGIVWKAYDKRSRETVALKKIFDAFRNPTDSQRTFREVMFLQEFGKHPNVIKLYN 78
Query: 768 -FSESTEKFMYIAVELCSASLEDVIEGSKGLAKNVAVQKNIDPINVLFQITSGVNHLHSM 826
F ++ +Y+A E A L +VI K ++ K++ ++ Q+ + LHS
Sbjct: 79 IFRADNDRDIYLAFEFMEADLHNVI-------KKGSILKDVHKQYIMCQLFRAIRFLHSG 131
Query: 827 KIVHRDLKPQNILIAPPKRYLSLHASKNKFRVLISDFGLCKKLEIDE---SSFRTNNFNN 883
++HRDLKP N+L+ RV ++DFGL + L E + +
Sbjct: 132 NVLHRDLKPSNVLL------------DADCRVKLADFGLARSLSSLEDYPEGQKMPDLTE 179
Query: 884 PTGTSGWRAPEIISGEVSLSESFAXXXXXXXXXXXXXXLDVNHMDLVTKKRLTRAVDIFS 943
T +R+PEI L+ KR T+ VD++S
Sbjct: 180 YVATRWYRSPEI---------------------------------LLAAKRYTKGVDMWS 206
Query: 944 LGCIFYYVL 952
LGCI +L
Sbjct: 207 LGCILAEML 215
>CE28251 [D] KOG0615 Serine/threonine protein kinase Chk2 and related proteins
Length = 469
Score = 72.4 bits (176), Expect = 4e-12
Identities = 79/322 (24%), Positives = 129/322 (39%), Gaps = 78/322 (24%)
Query: 710 ISSRVLGYGSSGTVVFQGKFQNRPV-AVKRLLIDFYDIASKEIQLLSESDD--------- 759
++S +LG G G V+ K +R V A+K+L F S+ I + +
Sbjct: 170 VTSHLLGKGGFGKVLLGYKKSDRSVVAIKQLNTQFSTRCSRAIAKTRDIQNEVEVMKKLS 229
Query: 760 HPNVIRYYFSESTEKFMYIAVELCS-----ASLEDVIEGSKGLAKNVAVQKNIDPINVLF 814
HPN++ Y + K+ Y+ +E + L D GL +++ F
Sbjct: 230 HPNIVAIYDCITVAKYSYMVIEYVGGGEFFSKLVDSKYNQMGLGESLGKY-------FAF 282
Query: 815 QITSGVNHLHSMKIVHRDLKPQNILIAPPKRYLSLHASKNKFRVLISDFGLCKKLEIDES 874
Q+ V +LHS+ I HRD+KP+NIL + L ++DFG+ K
Sbjct: 283 QLIDAVLYLHSVGICHRDIKPENILCSNKAERCILK---------LTDFGMAKN------ 327
Query: 875 SFRTNNFNNPTGTSGWRAPEIISGEVSLSESFAXXXXXXXXXXXXXXLDVNHMDLVTKKR 934
N GT + APEI++ +
Sbjct: 328 --SVNRMKTHCGTPSYCAPEIVANQ--------------------------------GVE 353
Query: 935 LTRAVDIFSLGCIFYYVLSKGEHPFGDRILREANILKGDYRLDGIKKSIQER--SVCIEA 992
T VDI+SLGC+ + S G PF + E LK D ++ + E+ + E
Sbjct: 354 YTPKVDIWSLGCVLFITFS-GYPPFSE----EYTDLKMDEQVLTGRLFFHEQWHRITDET 408
Query: 993 ADLIKSMLEQNPLLRPASDEIL 1014
++I+ ML PL+RP++ E++
Sbjct: 409 QNMIQWMLTVEPLIRPSAVELM 430
>At1g50700 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-Hand protein
superfamily
Length = 521
Score = 72.4 bits (176), Expect = 4e-12
Identities = 84/318 (26%), Positives = 139/318 (43%), Gaps = 76/318 (23%)
Query: 712 SRVLGYGSSGTVVF-----QGK-FQNRPVAVKRLLI--DFYDIASKEIQLLSESDDHPNV 763
S+ LG G G GK F + ++ K+L+ D D+ +EIQ++ PN+
Sbjct: 76 SKELGRGQFGVTYLCTEKSTGKRFACKSISKKKLVTKGDKEDMR-REIQIMQHLSGQPNI 134
Query: 764 IRYYFSESTEKFMYIAVELCSAS-LEDVIEGSKGLAKNVAVQKNIDPINVLFQITSGVNH 822
+ + + EK + + +ELC+ L D I ++ A +V QI + VN
Sbjct: 135 VEFKGAYEDEKAVNLVMELCAGGELFDRILAKGHYSERAAA-------SVCRQIVNVVNI 187
Query: 823 LHSMKIVHRDLKPQNILIAPPKRYLSLHASKNKFRVLISDFGLCKKLEIDESSFRTNNFN 882
H M ++HRDLKP+N L L + K + +DFGL +E +
Sbjct: 188 CHFMGVMHRDLKPENFL---------LSSKDEKALIKATDFGLSVFIE------EGRVYK 232
Query: 883 NPTGTSGWRAPEIISGEVSLSESFAXXXXXXXXXXXXXXLDVNHMDLVTKKRLTRAVDIF 942
+ G++ + APE++ K+R + +DI+
Sbjct: 233 DIVGSAYYVAPEVL-----------------------------------KRRYGKEIDIW 257
Query: 943 SLGCIFYYVLSKGEHPF---GDRILREANILKGDYRLDGIKKSIQERSVCIEAADLIKSM 999
S G I Y +LS G PF ++ + +A IL+G+ + S S+ A DL++ M
Sbjct: 258 SAGIILYILLS-GVPPFWAETEKGIFDA-ILEGEIDFE----SQPWPSISNSAKDLVRRM 311
Query: 1000 LEQNPLLRPASDEILKHP 1017
L Q+P R ++ E+LKHP
Sbjct: 312 LTQDPKRRISAAEVLKHP 329
>Hs4505785 [G] KOG0599 Phosphorylase kinase gamma subunit
Length = 406
Score = 72.0 bits (175), Expect = 5e-12
Identities = 74/292 (25%), Positives = 124/292 (42%), Gaps = 59/292 (20%)
Query: 749 KEIQLLSESDDHPNVIRYYFSESTEKFMYIAVELCSASLEDVIEGSKGLAKNVAVQKNID 808
+E +L + HP++I S + FM++ +L E L + VA+ + +
Sbjct: 76 RETHILRQVAGHPHIITLIDSYESSSFMFLVFDLMRKG-----ELFDYLTEKVALSEK-E 129
Query: 809 PINVLFQITSGVNHLHSMKIVHRDLKPQNILIAPPKRYLSLHASKNKFRVLISDFGLCKK 868
+++ + V+ LH+ IVHRDLKP+NIL+ + ++ +SDFG
Sbjct: 130 TRSIMRSLLEAVSFLHANNIVHRDLKPENILL------------DDNMQIRLSDFGFSCH 177
Query: 869 LEIDESSFRTNNFNNPTGTSGWRAPEIISGEVSLSESFAXXXXXXXXXXXXXXLDVNHMD 928
LE E GT G+ APEI+ + S+ E
Sbjct: 178 LEPGE------KLRELCGTPGYLAPEIL--KCSMDE------------------------ 205
Query: 929 LVTKKRLTRAVDIFSLGCIFYYVLSKGEHPFGDR--ILREANILKGDYRLDGIKKSIQER 986
T + VD+++ G I + +L+ G PF R IL I++G Y+ +R
Sbjct: 206 --THPGYGKEVDLWACGVILFTLLA-GSPPFWHRRQILMLRMIMEGQYQFS--SPEWDDR 260
Query: 987 SVCIEAADLIKSMLEQNPLLRPASDEILKHPLFWGVSKKLEFLLKVSDRFEV 1038
S ++ DLI +L+ +P R +++ L+HP F + L RF V
Sbjct: 261 SSTVK--DLISRLLQVDPEARLTAEQALQHPFFERCEGSQPWNLTPRQRFRV 310
>CE27768 [R] KOG0586 Serine/threonine protein kinase
Length = 1096
Score = 72.0 bits (175), Expect = 5e-12
Identities = 68/270 (25%), Positives = 112/270 (41%), Gaps = 71/270 (26%)
Query: 749 KEIQLLSESDDHPNVIRYYFSESTEKFMYIAVELCSAS-LEDVIEGSKGLAKNVAVQKNI 807
+E++++ + D HPN+++ Y TE+ +Y+ +E S + D + + + A K
Sbjct: 168 REVKIMKQLD-HPNIVKLYQVMETEQTLYLVLEYASGGEVFDYLVAHGRMKEKEARAK-- 224
Query: 808 DPINVLFQITSGVNHLHSMKIVHRDLKPQNILIAPPKRYLSLHASKNKFRVLISDFGLCK 867
QI S V +LHS I+HRDLK +N+L+ + I+DFG
Sbjct: 225 -----FRQIVSAVQYLHSKNIIHRDLKAENLLL------------DQDMNIKIADFGFSN 267
Query: 868 KLEIDESSFRTNNFNNPTGTSGWRAPEIISGEVSLSESFAXXXXXXXXXXXXXXLDVNHM 927
+ N + G+ + APE+ SG
Sbjct: 268 TFSLG------NKLDTFCGSPPYAAPELFSG----------------------------- 292
Query: 928 DLVTKKRLTRAVDIFSLGCIFYYVLSKGEHPFGDRILRE--ANILKGDYRLDGIKKSIQE 985
KK VD++SLG I Y ++S G PF + L+E +L+G YR+ +
Sbjct: 293 ----KKYDGPEVDVWSLGVILYTLVS-GSLPFDGQNLKELRERVLRGKYRIPFYMST--- 344
Query: 986 RSVCIEAADLIKSMLEQNPLLRPASDEILK 1015
+ +L+K L NP R + D I+K
Sbjct: 345 -----DCENLLKKFLVINPQRRSSLDNIMK 369
>CE23838 [R] KOG0586 Serine/threonine protein kinase
Length = 1192
Score = 72.0 bits (175), Expect = 5e-12
Identities = 68/270 (25%), Positives = 112/270 (41%), Gaps = 71/270 (26%)
Query: 749 KEIQLLSESDDHPNVIRYYFSESTEKFMYIAVELCSAS-LEDVIEGSKGLAKNVAVQKNI 807
+E++++ + D HPN+++ Y TE+ +Y+ +E S + D + + + A K
Sbjct: 216 REVKIMKQLD-HPNIVKLYQVMETEQTLYLVLEYASGGEVFDYLVAHGRMKEKEARAK-- 272
Query: 808 DPINVLFQITSGVNHLHSMKIVHRDLKPQNILIAPPKRYLSLHASKNKFRVLISDFGLCK 867
QI S V +LHS I+HRDLK +N+L+ + I+DFG
Sbjct: 273 -----FRQIVSAVQYLHSKNIIHRDLKAENLLL------------DQDMNIKIADFGFSN 315
Query: 868 KLEIDESSFRTNNFNNPTGTSGWRAPEIISGEVSLSESFAXXXXXXXXXXXXXXLDVNHM 927
+ N + G+ + APE+ SG
Sbjct: 316 TFSLG------NKLDTFCGSPPYAAPELFSG----------------------------- 340
Query: 928 DLVTKKRLTRAVDIFSLGCIFYYVLSKGEHPFGDRILRE--ANILKGDYRLDGIKKSIQE 985
KK VD++SLG I Y ++S G PF + L+E +L+G YR+ +
Sbjct: 341 ----KKYDGPEVDVWSLGVILYTLVS-GSLPFDGQNLKELRERVLRGKYRIPFYMST--- 392
Query: 986 RSVCIEAADLIKSMLEQNPLLRPASDEILK 1015
+ +L+K L NP R + D I+K
Sbjct: 393 -----DCENLLKKFLVINPQRRSSLDNIMK 417
>At3g19100 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-Hand protein
superfamily
Length = 599
Score = 72.0 bits (175), Expect = 5e-12
Identities = 79/308 (25%), Positives = 129/308 (41%), Gaps = 70/308 (22%)
Query: 726 QGKFQNRPVAVKRL-------LIDFYDIASKEIQLLSESDDHPNVIRYYFSESTEKFMYI 778
+G+ +++ VAVK + I D+ +E+++L H N++++Y + +YI
Sbjct: 165 KGELKDQEVAVKVIPKSKMTSAISIEDVR-REVKILRALSGHQNLVQFYDAFEDNANVYI 223
Query: 779 AVELCSAS-LEDVIEGSKGLAKNVAVQKNIDPINVLFQITSGVNHLHSMKIVHRDLKPQN 837
+ELC L D I LA+ ++ D VL QI + V H +VHRDLKP+N
Sbjct: 224 VMELCGGGELLDRI-----LARGGKYSED-DAKAVLIQILNVVAFCHLQGVVHRDLKPEN 277
Query: 838 ILIAPPKRYLSLHASKNKFRVL-ISDFGLCKKLEIDESSFRTNNFNNPTGTSGWRAPEII 896
L+ SK + +L + DFGL + DE N+ G++ + APE++
Sbjct: 278 F----------LYTSKEENSMLKVIDFGLSDFVRPDE------RLNDIVGSAYYVAPEVL 321
Query: 897 SGEVSLSESFAXXXXXXXXXXXXXXLDVNHMDLVTKKRLTRAVDIFSLGCIFYYVLSKGE 956
+ T D++S+G I Y +L G
Sbjct: 322 -----------------------------------HRSYTTEADVWSIGVIAYILLC-GS 345
Query: 957 HPFGDRILREANILKGDYRLDGIKKSIQERSVCIEAADLIKSMLEQNPLLRPASDEILKH 1016
PF R E+ I + + D S+ EA D +K +L ++P R + + L H
Sbjct: 346 RPFWAR--TESGIFRAVLKADPSFDEPPWPSLSFEAKDFVKRLLYKDPRKRMTASQALMH 403
Query: 1017 PLFWGVSK 1024
P G K
Sbjct: 404 PWIAGYKK 411
>YDR507c [D] KOG0588 Serine/threonine protein kinase
Length = 1142
Score = 71.2 bits (173), Expect = 9e-12
Identities = 72/268 (26%), Positives = 115/268 (42%), Gaps = 76/268 (28%)
Query: 759 DHPNVIRYYFSESTEKFMYIAVELCSASLEDVIEGSKGLAKNVAVQKNIDP----INVLF 814
+HPNV+R Y T +Y+ +E KG N+ V++ P I
Sbjct: 89 NHPNVLRLYDVWETNTDLYLVLEYAE----------KGELFNLLVERGPLPEHEAIRFFR 138
Query: 815 QITSGVNHLHSMKIVHRDLKPQNILIAPPKRYLSLHASKNKFRVLISDFGLCKKLEIDES 874
QI GV++ H++ IVHRDLKP+N+L+ +K+ + I+DFG+ LE +
Sbjct: 139 QIIIGVSYCHALGIVHRDLKPENLLL------------DHKYNIKIADFGMA-ALETEGK 185
Query: 875 SFRTNNFNNPTGTSGWRAPEIISGEVSLSESFAXXXXXXXXXXXXXXLDVNHMDLVTKKR 934
T+ G+ + APEI+SG + FA
Sbjct: 186 LLETS-----CGSPHYAAPEIVSG--IPYQGFAS-------------------------- 212
Query: 935 LTRAVDIFSLGCIFYYVLSKGEHPFGDRILREANIL----KGDYRLDGIKKSIQERSVCI 990
D++S G I + +L+ G PF + +L KG++ + + +
Sbjct: 213 -----DVWSCGVILFALLT-GRLPFDEEDGNIRTLLLKVQKGEFEMP------SDDEISR 260
Query: 991 EAADLIKSMLEQNPLLRPASDEILKHPL 1018
EA DLI+ +L +P R + +ILKHPL
Sbjct: 261 EAQDLIRKILTVDPERRIKTRDILKHPL 288
>Hs4507831 [OUT] KOG0595 Serine/threonine-protein kinase involved in autophagy
Length = 1050
Score = 71.2 bits (173), Expect = 9e-12
Identities = 80/313 (25%), Positives = 132/313 (41%), Gaps = 66/313 (21%)
Query: 714 VLGYGSSGTVVFQGKFQNR---PVAVKRL----LIDFYDIASKEIQLLSESDDHPNVIRY 766
++G+G+ VVF+G+ + + VAVK + L + KEI++L E H N++
Sbjct: 21 LIGHGAFA-VVFKGRHREKHDLEVAVKCINKKNLAKSQTLLGKEIKILKELK-HENIVAL 78
Query: 767 YFSESTEKFMYIAVELCSAS-LEDVIEGSKGLAKNVAVQKNIDPINV-LFQITSGVNHLH 824
Y + +Y+ +E C+ L D + + L++ D I + L QI + LH
Sbjct: 79 YDFQEMANSVYLVMEYCNGGDLADYLHAMRTLSE--------DTIRLFLQQIAGAMRLLH 130
Query: 825 SMKIVHRDLKPQNILIAPPKRYLSLHASKNKFRVLISDFGLCKKLEIDESSFRTNNFNNP 884
S I+HRDLKPQNIL++ P A+ N RV I+DFG + L+ + +
Sbjct: 131 SKGIIHRDLKPQNILLSNP---AGRRANPNSIRVKIADFGFARYLQSNMMAATL------ 181
Query: 885 TGTSGWRAPEIISGEVSLSESFAXXXXXXXXXXXXXXLDVNHMDLVTKKRLTRAVDIFSL 944
G+ + APE+I + H D D++S+
Sbjct: 182 CGSPMYMAPEVIMSQ--------------------------HYD--------GKADLWSI 207
Query: 945 GCIFYYVLSKGEHPFGDRILREANILKGDYRLDGIKKSIQERSVCIEAADLIKSMLEQNP 1004
G I Y L+ G+ PF ++ + Y + R L+ ++L++N
Sbjct: 208 GTIVYQCLT-GKAPFQASSPQDLRLF---YEKNKTLVPTIPRETSAPLRQLLLALLQRNH 263
Query: 1005 LLRPASDEILKHP 1017
R DE HP
Sbjct: 264 KDRMDFDEFFHHP 276
>Hs20127418 [T] KOG0033 Ca2+/calmodulin-dependent protein kinase EF-Hand protein
superfamily
Length = 664
Score = 70.9 bits (172), Expect = 1e-11
Identities = 73/263 (27%), Positives = 109/263 (40%), Gaps = 67/263 (25%)
Query: 760 HPNVIRYYFSESTEKFMYIAVELCSAS--LEDVIEGSKGLAKNVAVQKNIDPINVLFQIT 817
H N++R + S S E F Y+ +L + ED++ D + + QI
Sbjct: 70 HSNIVRLHDSISEEGFHYLVFDLVTGGELFEDIVARE--------YYSEADASHCIQQIL 121
Query: 818 SGVNHLHSMKIVHRDLKPQNILIAPPKRYLSLHASKNK-FRVLISDFGLCKKLEIDESSF 876
V H H M +VHRDLKP+N+L+ ASK K V ++DFGL +++ D+ +
Sbjct: 122 EAVLHCHQMGVVHRDLKPENLLL----------ASKCKGAAVKLADFGLAIEVQGDQQA- 170
Query: 877 RTNNFNNPTGTSGWRAPEIISGEVSLSESFAXXXXXXXXXXXXXXLDVNHMDLVTKKRLT 936
+ GT G+ +PE++ K+
Sbjct: 171 ----WFGFAGTPGYLSPEVL----------------------------------RKEAYG 192
Query: 937 RAVDIFSLGCIFYYVLSKGEHPFGDRILRE--ANILKGDYRLDGIKKSIQERSVCIEAAD 994
+ VDI++ G I Y+L G PF D + I G Y S + +V EA +
Sbjct: 193 KPVDIWACGVIL-YILLVGYPPFWDEDQHKLYQQIKAGAYDF----PSPEWDTVTPEAKN 247
Query: 995 LIKSMLEQNPLLRPASDEILKHP 1017
LI ML NP R + E LKHP
Sbjct: 248 LINQMLTINPAKRITAHEALKHP 270
>At1g14000 [T] KOG0192 Tyrosine kinase specific for activated (GTP-bound)
p21cdc42Hs
Length = 438
Score = 70.9 bits (172), Expect = 1e-11
Identities = 78/314 (24%), Positives = 134/314 (41%), Gaps = 68/314 (21%)
Query: 711 SSRVLGYGSSGTVVFQGKFQNRPVAVKRLLIDFYDIA------SKEIQLLSESDDHPNVI 764
++ ++G GS G +V + ++ PVAVKR+L D E+ LL + HPN++
Sbjct: 164 NAAMIGKGSFGEIV-KAYWRGTPVAVKRILPSLSDDRLVIQDFRHEVDLLVKLR-HPNIV 221
Query: 765 RYYFSESTEK-FMYIAVELCSASLEDVIEGSKGLAKNVAVQKNIDPINVLFQITSGVNHL 823
++ + + K M I L L ++ GL AV N I G+ +L
Sbjct: 222 QFLGAVTERKPLMLITEYLRGGDLHQYLKEKGGLTPTTAV-------NFALDIARGMTYL 274
Query: 824 HSMK--IVHRDLKPQNILIAPPKRYLSLHASKNKFRVLISDFGLCKKLEIDESSFRTNNF 881
H+ I+HRDLKP+N+L+ +++S + +V DFGL K +++ ++S
Sbjct: 275 HNEPNVIIHRDLKPRNVLL--------VNSSADHLKV--GDFGLSKLIKV-QNSHDVYKM 323
Query: 882 NNPTGTSGWRAPEIISGEVSLSESFAXXXXXXXXXXXXXXLDVNHMDLVTKKRLTRAVDI 941
TG+ + APE+ +R + VD+
Sbjct: 324 TGETGSYRYMAPEVFK----------------------------------HRRYDKKVDV 349
Query: 942 FSLGCIFYYVLSKGEHPFGDRILREANILKGDYRLDGIKKSIQERSVCIEAADLIKSMLE 1001
FS I Y +L +GE PF + EA + DG + + + + + +LI +
Sbjct: 350 FSFAMILYEML-EGEPPFANHEPYEA----AKHVSDGHRPTFRSKGCTPDLRELIVKCWD 404
Query: 1002 QNPLLRPASDEILK 1015
+ RP+ +ILK
Sbjct: 405 ADMNQRPSFLDILK 418
>7292679 [G] KOG0599 Phosphorylase kinase gamma subunit
Length = 560
Score = 70.9 bits (172), Expect = 1e-11
Identities = 71/274 (25%), Positives = 115/274 (41%), Gaps = 61/274 (22%)
Query: 749 KEIQLLSESDDHPNVIRYYFSESTEKFMYIAVELC-SASLEDVIEGSKGLAKNVAVQKNI 807
+EI +L + HP +I ++ F+++ ELC L D + L++
Sbjct: 76 QEISILRQVMGHPYIIDLQDVFESDAFVFLVFELCPKGELFDYLTSVVTLSEKKTR---- 131
Query: 808 DPINVLFQITSGVNHLHSMKIVHRDLKPQNILIAPPKRYLSLHASKNKFRVLISDFGLCK 867
++ QI GV ++H+ IVHRDLKP+NIL+ V I+DFG K
Sbjct: 132 ---TIMRQIFEGVEYIHAKSIVHRDLKPENILL------------DENHNVKITDFGFAK 176
Query: 868 KLEIDESSFRTNNFNNPTGTSGWRAPEIISGEVSLSESFAXXXXXXXXXXXXXXLDVNHM 927
+L+ E N GT G+ APE + + ++ E
Sbjct: 177 QLQEGE------KLTNLCGTPGYLAPETL--KCNMFEG---------------------- 206
Query: 928 DLVTKKRLTRAVDIFSLGCIFYYVLSKGEHPFGDR--ILREANILKGDYRLDGIKKSIQE 985
++ VDI++ G I + +L G PF R ++ NI++G Y S +
Sbjct: 207 ----SPGYSQEVDIWACGVIMFTLL-VGCPPFWHRKQMVMLRNIMEGKYSF----TSPEW 257
Query: 986 RSVCIEAADLIKSMLEQNPLLRPASDEILKHPLF 1019
+ + DLI+ L +P R E+L+HP F
Sbjct: 258 ADISEDPKDLIRKCLVVDPSQRITVKEVLRHPFF 291
>7290342 [G] KOG0658 Glycogen synthase kinase-3
Length = 1008
Score = 70.9 bits (172), Expect = 1e-11
Identities = 105/443 (23%), Positives = 174/443 (38%), Gaps = 104/443 (23%)
Query: 611 TQEVKIDTAISHKVNTNDIGKELSEKNTGNQDLPFDQNEGVSSETGTGDFEAXXXXXXXX 670
T +ID SH NT D+ + + G DL D + + G+G+
Sbjct: 460 TTRPQIDQQSSHHQNTEDVEQGAEPQIDGEADLDADAD---ADSDGSGENVKTAKLARTQ 516
Query: 671 XXXXXXXXXXXXXXXXLDDDGPMLDFKEFEQEGHLKHLSIS-SRVLGYGSSGTVVFQGKF 729
+ G D ++ +S + ++V+G GS G VVFQ K
Sbjct: 517 SCKNQTGRDGSKITTVVATPGQGTD--------RVQEVSYTDTKVIGNGSFG-VVFQAKL 567
Query: 730 --QNRPVAVKRLLIDFYDIASKEIQLLSESDDHPNVIR--YYFSESTEKFMYIAVELCSA 785
VA+K++L D ++E+Q++ + + H N+++ Y+F S EK + + L
Sbjct: 568 CDTGELVAIKKVLQD-RRFKNRELQIMRKLE-HCNIVKLLYFFYSSGEKRDEVFLNLV-- 623
Query: 786 SLEDVIEGSKGLAKNVAVQKNIDPINVL----FQITSGVNHLHSMKIVHRDLKPQNILIA 841
LE + E +A+ A K PIN + +Q+ + ++HS+ I HRD+KPQN+L+
Sbjct: 624 -LEYIPETVYKVARQYAKTKQTIPINFIRLYMYQLFRSLAYIHSLGICHRDIKPQNLLLD 682
Query: 842 PPKRYLSLHASKNKFRVLISDFGLCKKLEIDES--SFRTNNFNNPTGTSGWRAPEIISGE 899
P L L DFG K+L E S+ + + +RAPE+I G
Sbjct: 683 PETAVLKL-----------CDFGSAKQLLHGEPNVSYICSRY--------YRAPELIFGA 723
Query: 900 VSLSESFAXXXXXXXXXXXXXXLDVNHMDLVTKKRLTRAVDIFSLGCIFYYVLSKGEHPF 959
++ T +D++S GC+ +L G+ F
Sbjct: 724 IN---------------------------------YTTKIDVWSAGCVLAELL-LGQPIF 749
Query: 960 -GD------------------RILREANILKGDYRLDGIKKSIQERSVCI----EAADLI 996
GD +RE N +++ IK ++ I EA +L+
Sbjct: 750 PGDSGVDQLVEVIKVLGTPTREQIREMNPNYTEFKFPQIKSHPWQKVFRIRTPTEAINLV 809
Query: 997 KSMLEQNPLLRPASDEILKHPLF 1019
+LE P R + HP F
Sbjct: 810 SLLLEYTPSARITPLKACAHPFF 832
>Hs20070158 [T] KOG0201 Serine/threonine protein kinase
Length = 443
Score = 70.5 bits (171), Expect = 1e-11
Identities = 86/331 (25%), Positives = 140/331 (41%), Gaps = 76/331 (22%)
Query: 715 LGYGSSGTVVFQGKFQNRPVAVKRLLI-------DFYDIASKEIQLLSESDDHPNVIRYY 767
+G GS G V F+G NR V + I D + +EI +LS+ D P V +YY
Sbjct: 42 IGKGSFGEV-FKG-IDNRTQKVVAIKIIDLEEAEDEIEDIQQEITVLSQCDS-PYVTKYY 98
Query: 768 FSESTEKFMYIAVE-LCSASLEDVIEGSKGLAKNVAVQKNIDPINVLFQITSGVNHLHSM 826
S + ++I +E L S D++E +A +L +I G+++LHS
Sbjct: 99 GSYLKDTKLWIIMEYLGGGSALDLLEPGPLDETQIAT--------ILREILKGLDYLHSE 150
Query: 827 KIVHRDLKPQNILIAPPKRYLSLHASKNKFRVLISDFGLCKKLEIDESSFRTNNFNNPTG 886
K +HRD+K N+L LS H V ++DFG+ +L ++ + N F G
Sbjct: 151 KKIHRDIKAANVL-------LSEHG-----EVKLADFGVAGQL--TDTQIKRNTF---VG 193
Query: 887 TSGWRAPEIISGEVSLSESFAXXXXXXXXXXXXXXLDVNHMDLVTKKRLTRAVDIFSLGC 946
T W APE+I S++ DI+SLG
Sbjct: 194 TPFWMAPEVIKQSAYDSKA----------------------------------DIWSLG- 218
Query: 947 IFYYVLSKGEHPFGDRILREANILKGDYRLDGIKKSIQERSVCIEAADLIKSMLEQNPLL 1006
I L++GE P E + +K + + E + + +++ L + P
Sbjct: 219 ITAIELARGEPPHS-----ELHPMKVLFLIPKNNPPTLEGNYSKPLKEFVEACLNKEPSF 273
Query: 1007 RPASDEILKHPLFWGVSKKLEFLLKVSDRFE 1037
RP + E+LKH +KK +L ++ DR++
Sbjct: 274 RPTAKELLKHKFILRNAKKTSYLTELIDRYK 304
>CE28061 [T] KOG0033 Ca2+/calmodulin-dependent protein kinase EF-Hand protein
superfamily
Length = 302
Score = 70.5 bits (171), Expect = 1e-11
Identities = 74/263 (28%), Positives = 110/263 (41%), Gaps = 68/263 (25%)
Query: 760 HPNVIRYYFSESTEKFMYIAVELCSAS--LEDVIEGSKGLAKNVAVQKNIDPINVLFQIT 817
HPN++R + S E F Y+ +L + ED++ D + + QI
Sbjct: 68 HPNIVRLHDSIQEESFHYLVFDLVTGGELFEDIVARE--------FYSEADASHCIQQIL 119
Query: 818 SGVNHLHSMKIVHRDLKPQNILIAPPKRYLSLHASKNK-FRVLISDFGLCKKLEIDESSF 876
+ + HS IVHRDLKP+N+L+ ASK K V ++DFGL +E+++S
Sbjct: 120 ESIAYCHSNGIVHRDLKPENLLL----------ASKAKGAAVKLADFGLA--IEVNDS-- 165
Query: 877 RTNNFNNPTGTSGWRAPEIISGEVSLSESFAXXXXXXXXXXXXXXLDVNHMDLVTKKRLT 936
++ GT G+ +PE++ K +
Sbjct: 166 --EAWHGFAGTPGYLSPEVLK----------------------------------KDPYS 189
Query: 937 RAVDIFSLGCIFYYVLSKGEHPFGDRILRE--ANILKGDYRLDGIKKSIQERSVCIEAAD 994
+ VDI++ G I Y+L G PF D A I G Y S + +V EA
Sbjct: 190 KPVDIWACGVIL-YILLVGYPPFWDEDQHRLYAQIKAGAYDY----PSPEWDTVTPEAKS 244
Query: 995 LIKSMLEQNPLLRPASDEILKHP 1017
LI SML NP R +D+ LK P
Sbjct: 245 LIDSMLTVNPKKRITADQALKVP 267
>CE28060 [T] KOG0033 Ca2+/calmodulin-dependent protein kinase EF-Hand protein
superfamily
Length = 302
Score = 70.5 bits (171), Expect = 1e-11
Identities = 74/263 (28%), Positives = 110/263 (41%), Gaps = 68/263 (25%)
Query: 760 HPNVIRYYFSESTEKFMYIAVELCSAS--LEDVIEGSKGLAKNVAVQKNIDPINVLFQIT 817
HPN++R + S E F Y+ +L + ED++ D + + QI
Sbjct: 68 HPNIVRLHDSIQEESFHYLVFDLVTGGELFEDIVARE--------FYSEADASHCIQQIL 119
Query: 818 SGVNHLHSMKIVHRDLKPQNILIAPPKRYLSLHASKNK-FRVLISDFGLCKKLEIDESSF 876
+ + HS IVHRDLKP+N+L+ ASK K V ++DFGL +E+++S
Sbjct: 120 ESIAYCHSNGIVHRDLKPENLLL----------ASKAKGAAVKLADFGLA--IEVNDS-- 165
Query: 877 RTNNFNNPTGTSGWRAPEIISGEVSLSESFAXXXXXXXXXXXXXXLDVNHMDLVTKKRLT 936
++ GT G+ +PE++ K +
Sbjct: 166 --EAWHGFAGTPGYLSPEVLK----------------------------------KDPYS 189
Query: 937 RAVDIFSLGCIFYYVLSKGEHPFGDRILRE--ANILKGDYRLDGIKKSIQERSVCIEAAD 994
+ VDI++ G I Y+L G PF D A I G Y S + +V EA
Sbjct: 190 KPVDIWACGVIL-YILLVGYPPFWDEDQHRLYAQIKAGAYDY----PSPEWDTVTPEAKS 244
Query: 995 LIKSMLEQNPLLRPASDEILKHP 1017
LI SML NP R +D+ LK P
Sbjct: 245 LIDSMLTVNPKKRITADQALKVP 267
>CE28059 [T] KOG0033 Ca2+/calmodulin-dependent protein kinase EF-Hand protein
superfamily
Length = 350
Score = 70.5 bits (171), Expect = 1e-11
Identities = 74/263 (28%), Positives = 110/263 (41%), Gaps = 68/263 (25%)
Query: 760 HPNVIRYYFSESTEKFMYIAVELCSAS--LEDVIEGSKGLAKNVAVQKNIDPINVLFQIT 817
HPN++R + S E F Y+ +L + ED++ D + + QI
Sbjct: 68 HPNIVRLHDSIQEESFHYLVFDLVTGGELFEDIVARE--------FYSEADASHCIQQIL 119
Query: 818 SGVNHLHSMKIVHRDLKPQNILIAPPKRYLSLHASKNK-FRVLISDFGLCKKLEIDESSF 876
+ + HS IVHRDLKP+N+L+ ASK K V ++DFGL +E+++S
Sbjct: 120 ESIAYCHSNGIVHRDLKPENLLL----------ASKAKGAAVKLADFGLA--IEVNDS-- 165
Query: 877 RTNNFNNPTGTSGWRAPEIISGEVSLSESFAXXXXXXXXXXXXXXLDVNHMDLVTKKRLT 936
++ GT G+ +PE++ K +
Sbjct: 166 --EAWHGFAGTPGYLSPEVLK----------------------------------KDPYS 189
Query: 937 RAVDIFSLGCIFYYVLSKGEHPFGDRILRE--ANILKGDYRLDGIKKSIQERSVCIEAAD 994
+ VDI++ G I Y+L G PF D A I G Y S + +V EA
Sbjct: 190 KPVDIWACGVIL-YILLVGYPPFWDEDQHRLYAQIKAGAYDY----PSPEWDTVTPEAKS 244
Query: 995 LIKSMLEQNPLLRPASDEILKHP 1017
LI SML NP R +D+ LK P
Sbjct: 245 LIDSMLTVNPKKRITADQALKVP 267
>CE28058 [T] KOG0033 Ca2+/calmodulin-dependent protein kinase EF-Hand protein
superfamily
Length = 571
Score = 70.5 bits (171), Expect = 1e-11
Identities = 74/263 (28%), Positives = 110/263 (41%), Gaps = 68/263 (25%)
Query: 760 HPNVIRYYFSESTEKFMYIAVELCSAS--LEDVIEGSKGLAKNVAVQKNIDPINVLFQIT 817
HPN++R + S E F Y+ +L + ED++ D + + QI
Sbjct: 68 HPNIVRLHDSIQEESFHYLVFDLVTGGELFEDIVARE--------FYSEADASHCIQQIL 119
Query: 818 SGVNHLHSMKIVHRDLKPQNILIAPPKRYLSLHASKNK-FRVLISDFGLCKKLEIDESSF 876
+ + HS IVHRDLKP+N+L+ ASK K V ++DFGL +E+++S
Sbjct: 120 ESIAYCHSNGIVHRDLKPENLLL----------ASKAKGAAVKLADFGLA--IEVNDS-- 165
Query: 877 RTNNFNNPTGTSGWRAPEIISGEVSLSESFAXXXXXXXXXXXXXXLDVNHMDLVTKKRLT 936
++ GT G+ +PE++ K +
Sbjct: 166 --EAWHGFAGTPGYLSPEVLK----------------------------------KDPYS 189
Query: 937 RAVDIFSLGCIFYYVLSKGEHPFGDRILRE--ANILKGDYRLDGIKKSIQERSVCIEAAD 994
+ VDI++ G I Y+L G PF D A I G Y S + +V EA
Sbjct: 190 KPVDIWACGVIL-YILLVGYPPFWDEDQHRLYAQIKAGAYDY----PSPEWDTVTPEAKS 244
Query: 995 LIKSMLEQNPLLRPASDEILKHP 1017
LI SML NP R +D+ LK P
Sbjct: 245 LIDSMLTVNPKKRITADQALKVP 267
>CE28057 [T] KOG0033 Ca2+/calmodulin-dependent protein kinase EF-Hand protein
superfamily
Length = 520
Score = 70.5 bits (171), Expect = 1e-11
Identities = 74/263 (28%), Positives = 110/263 (41%), Gaps = 68/263 (25%)
Query: 760 HPNVIRYYFSESTEKFMYIAVELCSAS--LEDVIEGSKGLAKNVAVQKNIDPINVLFQIT 817
HPN++R + S E F Y+ +L + ED++ D + + QI
Sbjct: 68 HPNIVRLHDSIQEESFHYLVFDLVTGGELFEDIVARE--------FYSEADASHCIQQIL 119
Query: 818 SGVNHLHSMKIVHRDLKPQNILIAPPKRYLSLHASKNK-FRVLISDFGLCKKLEIDESSF 876
+ + HS IVHRDLKP+N+L+ ASK K V ++DFGL +E+++S
Sbjct: 120 ESIAYCHSNGIVHRDLKPENLLL----------ASKAKGAAVKLADFGLA--IEVNDS-- 165
Query: 877 RTNNFNNPTGTSGWRAPEIISGEVSLSESFAXXXXXXXXXXXXXXLDVNHMDLVTKKRLT 936
++ GT G+ +PE++ K +
Sbjct: 166 --EAWHGFAGTPGYLSPEVLK----------------------------------KDPYS 189
Query: 937 RAVDIFSLGCIFYYVLSKGEHPFGDRILRE--ANILKGDYRLDGIKKSIQERSVCIEAAD 994
+ VDI++ G I Y+L G PF D A I G Y S + +V EA
Sbjct: 190 KPVDIWACGVIL-YILLVGYPPFWDEDQHRLYAQIKAGAYDY----PSPEWDTVTPEAKS 244
Query: 995 LIKSMLEQNPLLRPASDEILKHP 1017
LI SML NP R +D+ LK P
Sbjct: 245 LIDSMLTVNPKKRITADQALKVP 267
>CE28056 [T] KOG0033 Ca2+/calmodulin-dependent protein kinase EF-Hand protein
superfamily
Length = 518
Score = 70.5 bits (171), Expect = 1e-11
Identities = 74/263 (28%), Positives = 110/263 (41%), Gaps = 68/263 (25%)
Query: 760 HPNVIRYYFSESTEKFMYIAVELCSAS--LEDVIEGSKGLAKNVAVQKNIDPINVLFQIT 817
HPN++R + S E F Y+ +L + ED++ D + + QI
Sbjct: 68 HPNIVRLHDSIQEESFHYLVFDLVTGGELFEDIVARE--------FYSEADASHCIQQIL 119
Query: 818 SGVNHLHSMKIVHRDLKPQNILIAPPKRYLSLHASKNK-FRVLISDFGLCKKLEIDESSF 876
+ + HS IVHRDLKP+N+L+ ASK K V ++DFGL +E+++S
Sbjct: 120 ESIAYCHSNGIVHRDLKPENLLL----------ASKAKGAAVKLADFGLA--IEVNDS-- 165
Query: 877 RTNNFNNPTGTSGWRAPEIISGEVSLSESFAXXXXXXXXXXXXXXLDVNHMDLVTKKRLT 936
++ GT G+ +PE++ K +
Sbjct: 166 --EAWHGFAGTPGYLSPEVLK----------------------------------KDPYS 189
Query: 937 RAVDIFSLGCIFYYVLSKGEHPFGDRILRE--ANILKGDYRLDGIKKSIQERSVCIEAAD 994
+ VDI++ G I Y+L G PF D A I G Y S + +V EA
Sbjct: 190 KPVDIWACGVIL-YILLVGYPPFWDEDQHRLYAQIKAGAYDY----PSPEWDTVTPEAKS 244
Query: 995 LIKSMLEQNPLLRPASDEILKHP 1017
LI SML NP R +D+ LK P
Sbjct: 245 LIDSMLTVNPKKRITADQALKVP 267
>CE28055 [T] KOG0033 Ca2+/calmodulin-dependent protein kinase EF-Hand protein
superfamily
Length = 533
Score = 70.5 bits (171), Expect = 1e-11
Identities = 74/263 (28%), Positives = 110/263 (41%), Gaps = 68/263 (25%)
Query: 760 HPNVIRYYFSESTEKFMYIAVELCSAS--LEDVIEGSKGLAKNVAVQKNIDPINVLFQIT 817
HPN++R + S E F Y+ +L + ED++ D + + QI
Sbjct: 68 HPNIVRLHDSIQEESFHYLVFDLVTGGELFEDIVARE--------FYSEADASHCIQQIL 119
Query: 818 SGVNHLHSMKIVHRDLKPQNILIAPPKRYLSLHASKNK-FRVLISDFGLCKKLEIDESSF 876
+ + HS IVHRDLKP+N+L+ ASK K V ++DFGL +E+++S
Sbjct: 120 ESIAYCHSNGIVHRDLKPENLLL----------ASKAKGAAVKLADFGLA--IEVNDS-- 165
Query: 877 RTNNFNNPTGTSGWRAPEIISGEVSLSESFAXXXXXXXXXXXXXXLDVNHMDLVTKKRLT 936
++ GT G+ +PE++ K +
Sbjct: 166 --EAWHGFAGTPGYLSPEVLK----------------------------------KDPYS 189
Query: 937 RAVDIFSLGCIFYYVLSKGEHPFGDRILRE--ANILKGDYRLDGIKKSIQERSVCIEAAD 994
+ VDI++ G I Y+L G PF D A I G Y S + +V EA
Sbjct: 190 KPVDIWACGVIL-YILLVGYPPFWDEDQHRLYAQIKAGAYDY----PSPEWDTVTPEAKS 244
Query: 995 LIKSMLEQNPLLRPASDEILKHP 1017
LI SML NP R +D+ LK P
Sbjct: 245 LIDSMLTVNPKKRITADQALKVP 267
>CE28054 [T] KOG0033 Ca2+/calmodulin-dependent protein kinase EF-Hand protein
superfamily
Length = 482
Score = 70.5 bits (171), Expect = 1e-11
Identities = 74/263 (28%), Positives = 110/263 (41%), Gaps = 68/263 (25%)
Query: 760 HPNVIRYYFSESTEKFMYIAVELCSAS--LEDVIEGSKGLAKNVAVQKNIDPINVLFQIT 817
HPN++R + S E F Y+ +L + ED++ D + + QI
Sbjct: 68 HPNIVRLHDSIQEESFHYLVFDLVTGGELFEDIVARE--------FYSEADASHCIQQIL 119
Query: 818 SGVNHLHSMKIVHRDLKPQNILIAPPKRYLSLHASKNK-FRVLISDFGLCKKLEIDESSF 876
+ + HS IVHRDLKP+N+L+ ASK K V ++DFGL +E+++S
Sbjct: 120 ESIAYCHSNGIVHRDLKPENLLL----------ASKAKGAAVKLADFGLA--IEVNDS-- 165
Query: 877 RTNNFNNPTGTSGWRAPEIISGEVSLSESFAXXXXXXXXXXXXXXLDVNHMDLVTKKRLT 936
++ GT G+ +PE++ K +
Sbjct: 166 --EAWHGFAGTPGYLSPEVLK----------------------------------KDPYS 189
Query: 937 RAVDIFSLGCIFYYVLSKGEHPFGDRILRE--ANILKGDYRLDGIKKSIQERSVCIEAAD 994
+ VDI++ G I Y+L G PF D A I G Y S + +V EA
Sbjct: 190 KPVDIWACGVIL-YILLVGYPPFWDEDQHRLYAQIKAGAYDY----PSPEWDTVTPEAKS 244
Query: 995 LIKSMLEQNPLLRPASDEILKHP 1017
LI SML NP R +D+ LK P
Sbjct: 245 LIDSMLTVNPKKRITADQALKVP 267
>CE28053 [T] KOG0033 Ca2+/calmodulin-dependent protein kinase EF-Hand protein
superfamily
Length = 720
Score = 70.5 bits (171), Expect = 1e-11
Identities = 74/263 (28%), Positives = 110/263 (41%), Gaps = 68/263 (25%)
Query: 760 HPNVIRYYFSESTEKFMYIAVELCSAS--LEDVIEGSKGLAKNVAVQKNIDPINVLFQIT 817
HPN++R + S E F Y+ +L + ED++ D + + QI
Sbjct: 68 HPNIVRLHDSIQEESFHYLVFDLVTGGELFEDIVARE--------FYSEADASHCIQQIL 119
Query: 818 SGVNHLHSMKIVHRDLKPQNILIAPPKRYLSLHASKNK-FRVLISDFGLCKKLEIDESSF 876
+ + HS IVHRDLKP+N+L+ ASK K V ++DFGL +E+++S
Sbjct: 120 ESIAYCHSNGIVHRDLKPENLLL----------ASKAKGAAVKLADFGLA--IEVNDS-- 165
Query: 877 RTNNFNNPTGTSGWRAPEIISGEVSLSESFAXXXXXXXXXXXXXXLDVNHMDLVTKKRLT 936
++ GT G+ +PE++ K +
Sbjct: 166 --EAWHGFAGTPGYLSPEVLK----------------------------------KDPYS 189
Query: 937 RAVDIFSLGCIFYYVLSKGEHPFGDRILRE--ANILKGDYRLDGIKKSIQERSVCIEAAD 994
+ VDI++ G I Y+L G PF D A I G Y S + +V EA
Sbjct: 190 KPVDIWACGVIL-YILLVGYPPFWDEDQHRLYAQIKAGAYDY----PSPEWDTVTPEAKS 244
Query: 995 LIKSMLEQNPLLRPASDEILKHP 1017
LI SML NP R +D+ LK P
Sbjct: 245 LIDSMLTVNPKKRITADQALKVP 267
>CE28051 [T] KOG0033 Ca2+/calmodulin-dependent protein kinase EF-Hand protein
superfamily
Length = 559
Score = 70.5 bits (171), Expect = 1e-11
Identities = 74/263 (28%), Positives = 110/263 (41%), Gaps = 68/263 (25%)
Query: 760 HPNVIRYYFSESTEKFMYIAVELCSAS--LEDVIEGSKGLAKNVAVQKNIDPINVLFQIT 817
HPN++R + S E F Y+ +L + ED++ D + + QI
Sbjct: 68 HPNIVRLHDSIQEESFHYLVFDLVTGGELFEDIVARE--------FYSEADASHCIQQIL 119
Query: 818 SGVNHLHSMKIVHRDLKPQNILIAPPKRYLSLHASKNK-FRVLISDFGLCKKLEIDESSF 876
+ + HS IVHRDLKP+N+L+ ASK K V ++DFGL +E+++S
Sbjct: 120 ESIAYCHSNGIVHRDLKPENLLL----------ASKAKGAAVKLADFGLA--IEVNDS-- 165
Query: 877 RTNNFNNPTGTSGWRAPEIISGEVSLSESFAXXXXXXXXXXXXXXLDVNHMDLVTKKRLT 936
++ GT G+ +PE++ K +
Sbjct: 166 --EAWHGFAGTPGYLSPEVLK----------------------------------KDPYS 189
Query: 937 RAVDIFSLGCIFYYVLSKGEHPFGDRILRE--ANILKGDYRLDGIKKSIQERSVCIEAAD 994
+ VDI++ G I Y+L G PF D A I G Y S + +V EA
Sbjct: 190 KPVDIWACGVIL-YILLVGYPPFWDEDQHRLYAQIKAGAYDY----PSPEWDTVTPEAKS 244
Query: 995 LIKSMLEQNPLLRPASDEILKHP 1017
LI SML NP R +D+ LK P
Sbjct: 245 LIDSMLTVNPKKRITADQALKVP 267
>7291043 [T] KOG0660 Mitogen-activated protein kinase
Length = 392
Score = 70.5 bits (171), Expect = 1e-11
Identities = 74/319 (23%), Positives = 126/319 (39%), Gaps = 87/319 (27%)
Query: 734 VAVKRLLIDFYDIAS-----KEIQLLSESDDHPNVIRYY--FSESTEKFMYIAVELCSAS 786
VA+K++ F D +E+ L HPN++R F S Y+ E +
Sbjct: 51 VALKKVFDAFRDETDAQRTYREVIFLRAFRCHPNIVRLVDIFKASNNLDFYLVFEFMESD 110
Query: 787 LEDVIEGSKGLAKNVAVQKNIDPINVLFQITSGVNHLHSMKIVHRDLKPQNILIAPPKRY 846
L +VI K V K++ V++Q+ + + +HS ++HRDLKP NILI
Sbjct: 111 LHNVI-------KRGNVLKDVHKRFVMYQLINAIKFIHSGNVIHRDLKPSNILI------ 157
Query: 847 LSLHASKNKFRVLISDFGLCKKL---EIDESSFRTNNFNNPTGTSGWRAPEIISGEVSLS 903
+K R+ ++DFGL + L I + + + T +RAPEI
Sbjct: 158 ------DSKCRLKVADFGLARTLSSRRIYDDLEQDGMLTDYVATRWYRAPEI-------- 203
Query: 904 ESFAXXXXXXXXXXXXXXLDVNHMDLVTKKRLTRAVDIFSLGCIFYYVLSKGEHPFGDRI 963
LV + T+ +D++ LGCI ++ + G
Sbjct: 204 -------------------------LVASRNYTKGIDMWGLGCILGEMIRQKPLFQGTST 238
Query: 964 LRE--------ANILKGDYRLDG-------IKKSIQE----------RSVCIEAADLIKS 998
+ + N+ K D G + ++IQ ++ C + L+K+
Sbjct: 239 VNQIEKIVTSLPNVTKLDIASIGPSFGSVLLSRNIQRDRRYSLDEMMKNCCDDGISLVKA 298
Query: 999 MLEQNPLLRPASDEILKHP 1017
+L NP R + E ++HP
Sbjct: 299 LLVLNPHNRLTAKEAIRHP 317
>Hs7657526 [T] KOG0603 Ribosomal protein S6 kinase
Length = 745
Score = 70.1 bits (170), Expect = 2e-11
Identities = 75/275 (27%), Positives = 117/275 (42%), Gaps = 65/275 (23%)
Query: 748 SKEIQLLSESDDHPNVIRYYFSESTEKFMYIAVELCSAS-LEDVIEGSKGLAKNVAVQKN 806
S+EI++L HPN+I +++Y+ +L L D I K ++ A
Sbjct: 465 SEEIEILMRYGQHPNIITLKDVFDDGRYVYLVTDLMKGGELLDRILKQKCFSEREAS--- 521
Query: 807 IDPINVLFQITSGVNHLHSMKIVHRDLKPQNILIAPPKRYLSLHASKNKFRVLISDFGLC 866
++L+ I+ V++LH +VHRDLKP NIL Y+ AS + R I DFG
Sbjct: 522 ----DILYVISKTVDYLHCQGVVHRDLKPSNIL------YMDESASADSIR--ICDFGFA 569
Query: 867 KKLEIDESSFRTNNFNNPTGTSGWRAPEIISGEVSLSESFAXXXXXXXXXXXXXXLDVNH 926
K+L + T P T+ + APE++
Sbjct: 570 KQLRGENGLLLT-----PCYTANFVAPEVL------------------------------ 594
Query: 927 MDLVTKKRLTRAVDIFSLGCIFYYVLSKGEHPF--GDRILREANILK---GDYRLDGIKK 981
++ A DI+SLG +FY +L+ G PF G E +L+ G + L G
Sbjct: 595 ----MQQGYDAACDIWSLGVLFYTMLA-GYTPFANGPNDTPEEILLRIGNGKFSLSGGNW 649
Query: 982 SIQERSVCIEAADLIKSMLEQNPLLRPASDEILKH 1016
++ A DL+ ML +P R +++ILKH
Sbjct: 650 D----NISDGAKDLLSHMLHMDPHQRYTAEQILKH 680
>Hs4826675 [UT] KOG0662 Cyclin-dependent kinase CDK5
Length = 292
Score = 70.1 bits (170), Expect = 2e-11
Identities = 83/342 (24%), Positives = 137/342 (39%), Gaps = 102/342 (29%)
Query: 715 LGYGSSGTVVFQGKFQNRP----VAVKRLLIDFYD-----IASKEIQLLSESDDHPNVIR 765
+G G+ GTV K +NR VA+KR+ +D D A +EI LL E H N++R
Sbjct: 10 IGEGTYGTVF---KAKNRETHEIVALKRVRLDDDDEGVPSSALREICLLKELK-HKNIVR 65
Query: 766 YYFSESTEKFMYIAVELCSASLEDVIEGSKGLAKNVAVQKNIDPINV---LFQITSGVNH 822
+ ++K + + E C L+ + G ++DP V LFQ+ G+
Sbjct: 66 LHDVLHSDKKLTLVFEFCDQDLKKYFDSCNG---------DLDPEIVKSFLFQLLKGLGF 116
Query: 823 LHSMKIVHRDLKPQNILIAPPKRYLSLHASKNKFRVLISDFGLCKKLEIDESSFRTNNFN 882
HS ++HRDLKPQN+LI + ++DFGL + I ++
Sbjct: 117 CHSRNVLHRDLKPQNLLI------------NRNGELKLADFGLARAFGIP-----VRCYS 159
Query: 883 NPTGTSGWRAPEIISGEVSLSESFAXXXXXXXXXXXXXXLDVNHMDLVTKKRLTRAVDIF 942
T +R P+++ G K + ++D++
Sbjct: 160 AEVVTLWYRPPDVLFG---------------------------------AKLYSTSIDMW 186
Query: 943 SLGCIFYYVLSKGEHPFGDRILREANILKGDYRLDGIKKSIQERSVC------------- 989
S GCIF + + G F + + LK +RL G Q S+
Sbjct: 187 SAGCIFAELANAGRPLFPGNDVDDQ--LKRIFRLLGTPTEEQWPSMTKLPDYKPYPMYPA 244
Query: 990 ------------IEAADLIKSMLEQNPLLRPASDEILKHPLF 1019
DL++++L+ NP+ R +++E L+HP F
Sbjct: 245 TTSLVNVVPKLNATGRDLLQNLLKCNPVQRISAEEALQHPYF 286
>YOL016c [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-Hand protein
superfamily
Length = 447
Score = 69.3 bits (168), Expect = 3e-11
Identities = 86/326 (26%), Positives = 133/326 (40%), Gaps = 66/326 (20%)
Query: 710 ISSRVLGYGSSGTVVFQGKFQ-NRPVAVKRLLIDFYDIASKEIQLLSESDD------HPN 762
I R LG GS G V K N VA+K LL + ++Q+L E HPN
Sbjct: 48 IFGRTLGAGSFGVVRQARKLSTNEDVAIKILLKKALQGNNVQLQMLYEELSILQKLSHPN 107
Query: 763 VIRYY-FSESTEKFMYIAVELCSASLEDVIEGSKGLAKNVAVQKNIDPINVLFQITSGVN 821
++ + + ES +KF + L D I S+G V D + ++ QI V
Sbjct: 108 IVSFKDWFESKDKFYIVTQLATGGELFDRIL-SRGKFTEV------DAVEIIVQILGAVE 160
Query: 822 HLHSMKIVHRDLKPQNILIAPPKRYLSLHASKNKFRVLISDFGLCKKLEIDESSFRTNNF 881
++HS +VHRDLKP+N+L + S+N ++I+DFG+ K+L+ +E +
Sbjct: 161 YMHSKNVVHRDLKPENVLY--------VDKSENS-PLVIADFGIAKQLKGEE-----DLI 206
Query: 882 NNPTGTSGWRAPEIISGEVSLSESFAXXXXXXXXXXXXXXLDVNHMDLVTKKRLTRAVDI 941
G+ G+ APE++ T+ + DI
Sbjct: 207 YKAAGSLGYVAPEVL----------------------------------TQDGHGKPCDI 232
Query: 942 FSLGCIFYYVLSKGEHPFGDRILREANILKGDYRLDGIKKSIQERSVCIEAADLIKSMLE 1001
+S+G I Y +L G PF + R ++ I+ I L
Sbjct: 233 WSIGVITYTLLC-GYSPFIAESVEGFMEECTASRYPVTFHMPYWDNISIDVKRFILKALR 291
Query: 1002 QNPLLRPASDEILKHPLFWGVSKKLE 1027
NP RP + E+L P W SK++E
Sbjct: 292 LNPADRPTATELLDDP--WITSKRVE 315
>YCR091w [R] KOG0610 Putative serine/threonine protein kinase
Length = 720
Score = 69.3 bits (168), Expect = 3e-11
Identities = 94/363 (25%), Positives = 147/363 (39%), Gaps = 105/363 (28%)
Query: 713 RVLGYGSSGTVVFQGKFQNRPVAVKRLLIDFYDIASKEIQ-LLSESD-----DHPNVIRY 766
R+LG G G V + + ++L I K+I+ +L+E + DHP ++
Sbjct: 328 RLLGQGDVGKVYLMRERDTNQIFALKVLNKHEMIKRKKIKRVLTEQEILATSDHPFIVTL 387
Query: 767 YFSESTEKFMYIAVELCSASLEDVIEGSKGLAKNVAVQKNIDPINVLF---QITSGVNHL 823
Y S T+ ++Y+ +E C G A K I + F ++ + + +L
Sbjct: 388 YHSFQTKDYLYLCMEYCMG-------GEFFRALQTRKSKCIAEEDAKFYASEVVAALEYL 440
Query: 824 HSMKIVHRDLKPQNILIAPPKRYLSLHASKNKFRVLISDFGL------CKKLEIDESS-- 875
H + ++RDLKP+NIL LH S + V++SDF L KK + +S+
Sbjct: 441 HLLGFIYRDLKPENIL---------LHQSGH---VMLSDFDLSIQATGSKKPTMKDSTYL 488
Query: 876 --------FRTNNFNNPTGTSGWRAPEIISGEVSLSESFAXXXXXXXXXXXXXXLDVNHM 927
FRTN+F GT + APE+I G H
Sbjct: 489 DTKICSDGFRTNSF---VGTEEYLAPEVIRGN-------------------------GH- 519
Query: 928 DLVTKKRLTRAVDIFSLGCIFYYVLSKGEHPFGDRILRE--ANILKGDYRLDGIKKSIQE 985
T AVD ++LG + Y +L G PF E +NIL D + +
Sbjct: 520 --------TAAVDWWTLGILIYEMLF-GCTPFKGDNSNETFSNILTKDVKFP------HD 564
Query: 986 RSVCIEAADLIKSMLEQNPLLRPASD----EILKHPLFWGVSKKLEFLLKVSDRFEVERR 1041
+ V DLIK +L +N R S +I +HP F KK+++ + +
Sbjct: 565 KEVSKNCKDLIKKLLNKNEAKRLGSKSGAADIKRHPFF----KKVQWSF-------LRNQ 613
Query: 1042 DPP 1044
DPP
Sbjct: 614 DPP 616
>Hs7706286 [T] KOG0033 Ca2+/calmodulin-dependent protein kinase EF-Hand protein
superfamily
Length = 489
Score = 69.3 bits (168), Expect = 3e-11
Identities = 72/265 (27%), Positives = 110/265 (41%), Gaps = 71/265 (26%)
Query: 760 HPNVIRYYFSESTEKFMYIAVELCSAS--LEDVIEGSKGLAKNVAVQKNIDPINVLFQIT 817
HPN++R + S S E Y+ +L + ED++ D + + QI
Sbjct: 69 HPNIVRLHDSISEEGHHYLIFDLVTGGELFEDIVARE--------YYSEADASHCIQQIL 120
Query: 818 SGVNHLHSMKIVHRDLKPQNILIAPPKRYLSLHASKNK-FRVLISDFGLCKKLEIDESSF 876
V H H M +VHRDLKP+N+L+ ASK K V ++DFGL ++E ++ +
Sbjct: 121 EAVLHCHQMGVVHRDLKPENLLL----------ASKLKGAAVKLADFGLAIEVEGEQQA- 169
Query: 877 RTNNFNNPTGTSGWRAPEIISGEVSLSESFAXXXXXXXXXXXXXXLDVNHMDLVTKKRLT 936
+ GT G+ +PE++ K
Sbjct: 170 ----WFGFAGTPGYLSPEVL----------------------------------RKDPYG 191
Query: 937 RAVDIFSLGCIFYYVLSKGEHPFGD----RILREANILKGDYRLDGIKKSIQERSVCIEA 992
+ VD+++ G I Y+L G PF D R+ ++ D+ S + +V EA
Sbjct: 192 KPVDLWACGVIL-YILLVGYPPFWDEDQHRLYQQIKAGAYDF------PSPEWDTVTPEA 244
Query: 993 ADLIKSMLEQNPLLRPASDEILKHP 1017
DLI ML NP R + E LKHP
Sbjct: 245 KDLINKMLTINPSKRITAAEALKHP 269
>CE29359 [T] KOG0200 Fibroblast/platelet-derived growth factor receptor and
related receptor tyrosine kinases
Length = 849
Score = 68.9 bits (167), Expect = 4e-11
Identities = 88/350 (25%), Positives = 157/350 (44%), Gaps = 75/350 (21%)
Query: 706 KHLSISSRVLGYGSSGTVVFQGKFQNR-----PVAVKRLLI-----DFYDIASKEIQLLS 755
K + + +G G+ GTV +GKF+N PVAVK+L + D + A E+++L
Sbjct: 537 KKIDCGTDQIGKGAFGTVK-KGKFRNSLGESVPVAVKKLGLRESSKDERNPAFSEMEIL- 594
Query: 756 ESDDHPNVIRYY-FSES-TEKFMYIAVELCSASLEDVIEGSKGLAKNVAVQKNIDPINVL 813
E HPN++ YY FS S E+ +Y+ EL SL+ I+ K+ A+ + +++L
Sbjct: 595 EMVAHPNIVFYYGFSISGDEQALYLLFELMDTSLDKFID------KSDAILSENERLDIL 648
Query: 814 FQITSGVNHLHSM--KIVHRDLKPQNILIAPPKRYLSLHASKNKFRVLISDFGLCKKLEI 871
QI G++ LH+ IVH DL +N+L+ Y+ + K I+D GL K +
Sbjct: 649 AQICRGMSFLHTRTPSIVHGDLAARNVLLKKHPVYIKKYICK------ITDLGLAKTC-L 701
Query: 872 DESSFRTNNFNNPTGTS-GWRAPEIISGEVSLSESFAXXXXXXXXXXXXXXLDVNHMDLV 930
DE ++++PT W PE++
Sbjct: 702 DE---LYTSYDDPTKIPFKWLPPEVLG--------------------------------- 725
Query: 931 TKKRLTRAVDIFSLGCIFYYVLSKGEHPFGDRILREANILKGDYRLDGIKKSIQERSVCI 990
+ L+ DI++ G + + V K P+G + +N+ + Y DG + E+ + +
Sbjct: 726 -SRTLSLKTDIWAFGIVCFEVCDKVGEPYG-ACVPTSNLCQ--YLTDGY---VHEKGLHM 778
Query: 991 EAA--DLIKSMLEQNPLLRPASDEILKHPLFWGVSKKLEFLLKVSDRFEV 1038
++ + Q+P+ RP+ E++ L + E +LK+ R ++
Sbjct: 779 SDTIYNIALDCMRQHPIERPSFAELVDQFLDHLIENDGEDVLKLKAREKI 828
>At3g01090 [T] KOG0583 Serine/threonine protein kinase
Length = 512
Score = 68.9 bits (167), Expect = 4e-11
Identities = 88/318 (27%), Positives = 126/318 (38%), Gaps = 80/318 (25%)
Query: 713 RVLGYGSSGTV-VFQGKFQNRPVAVKRLL------IDFYDIASKEIQLLSESDDHPNVIR 765
R LG GS G V + + VA+K L ++ + +EI++L HP++IR
Sbjct: 23 RTLGIGSFGRVKIAEHALTGHKVAIKILNRRKIKNMEMEEKVRREIKIL-RLFMHPHIIR 81
Query: 766 YYFSESTEKFMYIAVELC-SASLEDVIEGSKGLAKNVAVQKNIDPINVLFQITSGVNHLH 824
Y T +Y+ +E S L D I L ++ A N QI SGV + H
Sbjct: 82 LYEVIETPTDIYLVMEYVNSGELFDYIVEKGRLQEDEAR-------NFFQQIISGVEYCH 134
Query: 825 SMKIVHRDLKPQNILIAPPKRYLSLHASKNKFRVLISDFGLCKKLEIDESSFRTNNF-NN 883
+VHRDLKP+N+L+ +K V I+DFGL + R +F
Sbjct: 135 RNMVVHRDLKPENLLL------------DSKCNVKIADFGL-------SNIMRDGHFLKT 175
Query: 884 PTGTSGWRAPEIISGEVSLSESFAXXXXXXXXXXXXXXLDVNHMDLVTKKRLTRAVDIFS 943
G+ + APE+ISG++ VD++S
Sbjct: 176 SCGSPNYAAPEVISGKLYAGPE---------------------------------VDVWS 202
Query: 944 LGCIFYYVLSKGEHPFGDRILRE--ANILKGDYRLDGIKKSIQERSVCIEAADLIKSMLE 1001
G I Y +L G PF D + I G Y L + A DLI ML
Sbjct: 203 CGVILYALLC-GTLPFDDENIPNLFKKIKGGIYTLPS--------HLSPGARDLIPRMLV 253
Query: 1002 QNPLLRPASDEILKHPLF 1019
+P+ R EI +HP F
Sbjct: 254 VDPMKRVTIPEIRQHPWF 271
>SPBC19F8.07 [DKL] KOG0659 Cdk activating kinase (CAK)/RNA polymerase II
transcription initiation/nucleotide excision repair
factor TFIIH/TFIIK kinase subunit CDK7
Length = 335
Score = 68.6 bits (166), Expect = 6e-11
Identities = 87/349 (24%), Positives = 150/349 (42%), Gaps = 97/349 (27%)
Query: 710 ISSRVLGYGSSGTVVFQG--KFQNRPVAVKRLLI----DFYDIAS-KEIQLLSESDDHPN 762
+ R +G G+ VVF G K NR VA+K++ + D DI++ +EI+ L ES H N
Sbjct: 12 VKERKVGEGTYA-VVFLGRQKETNRRVAIKKIKVGQFKDGIDISALREIKFLRESR-HDN 69
Query: 763 VIRYYFSESTEKFMYIAVELCSASLEDVIEGSKGLAKNVAVQKNIDPINVLFQITSGVNH 822
VI ST+ + I +E + LE +I+ + + ++ + + + G++H
Sbjct: 70 VIELVDVFSTKSNLNIILEFLDSDLEMLIKDKFIVFQPAHIK------SWMVMLLRGLHH 123
Query: 823 LHSMKIVHRDLKPQNILIAPPKRYLSLHASKNKFRVLISDFGLCKKLEIDESSFRT-NNF 881
+HS I+HRDLKP N+LI+ + + ++DFGL + F T ++
Sbjct: 124 IHSRFILHRDLKPNNLLIS------------SDGVLKLADFGLSR-------DFGTPSHM 164
Query: 882 NNPTGTSGWRAPEIISGEVSLSESFAXXXXXXXXXXXXXXLDVNHMDLVTKKRLTRAVDI 941
++ T +R PE+ G S VD+
Sbjct: 165 SHQVITRWYRPPELFMGCRSYG---------------------------------TGVDM 191
Query: 942 FSLGCIFYYVLSKGEHPFGDRILREANILKGDYRLDG-----IKKSIQERSVCI------ 990
+S+GCIF ++ + + G+ L + N++ +R G + KS+Q+ +
Sbjct: 192 WSVGCIFAELMLRTPYLPGESDLDQLNVI---FRALGTPEPEVIKSMQQLPNYVEMKHIP 248
Query: 991 ---------------EAADLIKSMLEQNPLLRPASDEILKHPLFWGVSK 1024
E DL+K ML+ NP RP + + L+H F + K
Sbjct: 249 PPNGGMEALFSAAGHEEIDLLKMMLDYNPYRRPTAQQALEHHYFSALPK 297
>At1g53570 [T] KOG0198 MEKK and related serine/threonine protein kinases
Length = 608
Score = 68.6 bits (166), Expect = 6e-11
Identities = 78/316 (24%), Positives = 131/316 (40%), Gaps = 76/316 (24%)
Query: 713 RVLGYGSSGTVVFQ-GKFQNRPVAVKRLLIDFYDIASKE--------IQLLSESDDHPNV 763
+ LG G+ G V + + A+K + + D SKE I LL++ HPN+
Sbjct: 218 KFLGSGTFGQVYLGFNSEKGKMCAIKEVKVISDDQTSKECLKQLNQEINLLNQLC-HPNI 276
Query: 764 IRYYFSESTEKFMYIAVELCSASLEDVIEGSKGLAKNVAVQKNIDPINVLFQITSGVNHL 823
++YY SE +E+ + + +E S + G +Q N QI +G+ +L
Sbjct: 277 VQYYGSELSEETLSVYLEYVSGGSIHKLLKDYGSFTEPVIQ------NYTRQILAGLAYL 330
Query: 824 HSMKIVHRDLKPQNILIAPPKRYLSLHASKNKFRVLISDFGLCKKLEIDESSFRTNNFNN 883
H VHRD+K NIL+ P + ++DFG+ K + ++F T +
Sbjct: 331 HGRNTVHRDIKGANILVDP------------NGEIKLADFGMAKHV----TAFST--MLS 372
Query: 884 PTGTSGWRAPEIISGEVSLSESFAXXXXXXXXXXXXXXLDVNHMDLVTKKRLTRAVDIFS 943
G+ W APE++ +++ T AVDI+S
Sbjct: 373 FKGSPYWMAPEVV---------------------------------MSQNGYTHAVDIWS 399
Query: 944 LGCIFYYVLSKGEHPFGDRILREANILKGDYRLDGIKKSIQE--RSVCIEAADLIKSMLE 1001
LGC + + P + A I K G K E + +A + I+ L+
Sbjct: 400 LGCTILEMAT--SKPPWSQFEGVAAIFK-----IGNSKDTPEIPDHLSNDAKNFIRLCLQ 452
Query: 1002 QNPLLRPASDEILKHP 1017
+NP +RP + ++L+HP
Sbjct: 453 RNPTVRPTASQLLEHP 468
>7295431 [D] KOG0601 Cyclin-dependent kinase WEE1
Length = 770
Score = 68.6 bits (166), Expect = 6e-11
Identities = 65/285 (22%), Positives = 110/285 (37%), Gaps = 67/285 (23%)
Query: 749 KEIQLLSESDDHPNVIRYYFSESTEKFMYIAVELCSASLEDVIEGSKGLAKNVAVQKNID 808
+E++ E H N IR+ + +Y+ +ELC SLE + + + +
Sbjct: 148 EEVRRYEEFSGHENCIRFIRAWEQYDRLYMQMELCRESLEQYLLRCQRIPEERIW----- 202
Query: 809 PINVLFQITSGVNHLHSMKIVHRDLKPQNILIAPPKRYLSLHASKNKFRVLISDFGLCKK 868
++L + G+ LH ++H D+K N+LI L +DFGL
Sbjct: 203 --HILLDLLRGLKSLHDRNLIHLDIKLDNVLIGEDDETCKL-----------ADFGLV-- 247
Query: 869 LEIDESSFRTNNFNNPTGTSGWRAPEIISGEVSLSESFAXXXXXXXXXXXXXXLDVNHMD 928
+++D R N+ + G S + APEI+ G S
Sbjct: 248 IDVD----RANSHHATEGDSRYMAPEILQGHFS--------------------------- 276
Query: 929 LVTKKRLTRAVDIFSLGCIFYYVLSKGEHPFGDRILREANILKGDYRLDGIKKSIQERSV 988
+A DIFSLG + + P + E GI +
Sbjct: 277 --------KAADIFSLGIAMLELACYMDLPSNGPLWHELR--------HGILPEEFINKI 320
Query: 989 CIEAADLIKSMLEQNPLLRPASDEILKHPLFWGVSKKLEFLLKVS 1033
+E +IKSM++ +P RP ++++L HP + KK + L+ S
Sbjct: 321 SLELQSVIKSMMKPDPAQRPTAEQLLSHPKLQYLQKKRKSLMNFS 365
>Hs4826684_1 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-Hand protein
superfamily
Length = 370
Score = 68.6 bits (166), Expect = 6e-11
Identities = 74/272 (27%), Positives = 116/272 (42%), Gaps = 64/272 (23%)
Query: 749 KEIQLLSESDDHPNVIRYYFSESTEKFMYIAVELCSAS-LEDVIEGSKGLAKNVAVQKNI 807
+E+ +L E HPNVI + + + + +EL + L D + + L + A +
Sbjct: 63 REVSILKEIQ-HPNVITLHEVYENKTDVILILELVAGGELFDFLAEKESLTEEEATE--- 118
Query: 808 DPINVLFQITSGVNHLHSMKIVHRDLKPQNILIAPPKRYLSLHASKNKFRVLISDFGLCK 867
L QI +GV +LHS++I H DLKP+NI++ L + K R+ I DFGL
Sbjct: 119 ----FLKQILNGVYYLHSLQIAHFDLKPENIML--------LDRNVPKPRIKIIDFGLAH 166
Query: 868 KLEIDESSFRTNNFNNPTGTSGWRAPEIISGEVSLSESFAXXXXXXXXXXXXXXLDVNHM 927
K++ N F N GT + APEI++ E
Sbjct: 167 KIDFG------NEFKNIFGTPEFVAPEIVNYE---------------------------- 192
Query: 928 DLVTKKRLTRAVDIFSLGCIFYYVLSKGEHPFGDRILRE--ANILKGDYRLDGIKKSIQE 985
L D++S+G I Y +LS G PF +E AN+ +Y + S
Sbjct: 193 ------PLGLEADMWSIGVITYILLS-GASPFLGDTKQETLANVSAVNYEFEDEYFS--- 242
Query: 986 RSVCIEAADLIKSMLEQNPLLRPASDEILKHP 1017
+ A D I+ +L ++P R + L+HP
Sbjct: 243 -NTSALAKDFIRRLLVKDPKKRMTIQDSLQHP 273
>YFR014c [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 446
Score = 68.2 bits (165), Expect = 7e-11
Identities = 65/219 (29%), Positives = 104/219 (46%), Gaps = 41/219 (18%)
Query: 698 EFEQEGHLKHLSISSRV----------LGYGSSGTVVFQGKFQN--RPVAVKRLLIDFYD 745
E + EG + H+ +S V LG G+ G VV Q K VAVK L+
Sbjct: 16 EEDSEGKMAHVQPASYVNKKKYVFGKTLGAGTFG-VVRQAKNTETGEDVAVKILIKKALK 74
Query: 746 IASKEIQLLSESDD------HPNVIRYY-FSESTEKFMYIAVELCSASLEDVIEGSKGLA 798
+++ L + D HPN++ + + ES +KF I L D I L
Sbjct: 75 GNKVQLEALYDELDILQRLHHPNIVAFKDWFESKDKFYIITQLAKGGELFDRI-----LK 129
Query: 799 KNVAVQKNIDPINVLFQITSGVNHLHSMKIVHRDLKPQNILIAPPKRYLSLHASKNKFRV 858
K ++ D + +L +I S V ++HS IVHRDLKP+N+L Y+ ++ +
Sbjct: 130 KGKFTEE--DAVRILVEILSAVKYMHSQNIVHRDLKPENLL------YID---KSDESPL 178
Query: 859 LISDFGLCKKLEIDESSFRTNNFNNPTGTSGWRAPEIIS 897
+++DFG+ K+L+ DE P G+ G+ APE+++
Sbjct: 179 VVADFGIAKRLKSDEEL-----LYKPAGSLGYVAPEVLT 212
>7297680 [R] KOG0594 Protein kinase PCTAIRE and related kinases
Length = 297
Score = 68.2 bits (165), Expect = 7e-11
Identities = 87/345 (25%), Positives = 145/345 (41%), Gaps = 93/345 (26%)
Query: 715 LGYGSSGTVVFQGK--FQNRPVAVKRLLIDFYD-----IASKEIQLLSESDDHPNVIRYY 767
+G G+ G VV++G+ + VA+K++ ++ D A +EI LL E H N++
Sbjct: 10 IGEGTYG-VVYKGRNRLTGQIVAMKKIRLESDDEGVPSTAIREISLLKELK-HENIVCLE 67
Query: 768 FSESTEKFMYIAVELCSASLEDVIEGSKGLAKNVAVQKNIDPINV---LFQITSGVNHLH 824
E +Y+ E S L+ ++ ++ V K+++ V L+QITS + H
Sbjct: 68 DVLMEENRIYLIFEFLSMDLKKYMD-------SLPVDKHMESELVRSYLYQITSAILFCH 120
Query: 825 SMKIVHRDLKPQNILIAPPKRYLSLHASKNKFRVLISDFGLCKKLEIDESSFRTNNFNNP 884
+++HRDLKPQN+LI + ++DFGL + I + +
Sbjct: 121 RRRVLHRDLKPQNLLI------------DKSGLIKVADFGLGRSFGIP-----VRIYTHE 163
Query: 885 TGTSGWRAPEIISGEVSLSESFAXXXXXXXXXXXXXXLDVNHMDLVTKKRLTRAVDIFSL 944
T +RAPE++ G R + VDI+S+
Sbjct: 164 IVTLWYRAPEVLLG---------------------------------SPRYSCPVDIWSI 190
Query: 945 GCIFYYV-----LSKGEHPFGDRILREANILK--------GDYRLDGIKKSI-------- 983
GCIF + L +G+ D++ R ILK G L K +
Sbjct: 191 GCIFAEMATRKPLFQGDSEI-DQLFRMFRILKTPTEDIWPGVTSLPDYKNTFPCWSTNQL 249
Query: 984 --QERSVCIEAADLIKSMLEQNPLLRPASDEILKHPLFWGVSKKL 1026
Q +++ DLI+ ML +P+ R ++ +IL+HP F G L
Sbjct: 250 TNQLKNLDANGIDLIQKMLIYDPVHRISAKDILEHPYFNGFQSGL 294
>SPAC23A1.06c [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-Hand protein
superfamily
Length = 504
Score = 67.8 bits (164), Expect = 1e-10
Identities = 72/303 (23%), Positives = 124/303 (40%), Gaps = 78/303 (25%)
Query: 749 KEIQLLSESDDHPNVIRYYFSESTEKFMYIAVELCSAS-LEDVIEGSKGLAKNVAVQKNI 807
KE+ ++ H NV+ + TE F ++ +EL L I ++N+A
Sbjct: 111 KEVNIMRRVK-HKNVVNLFDFVETEDFYHLVMELAEGGELFHQIVNFTYFSENLAR---- 165
Query: 808 DPINVLFQITSGVNHLHSM-KIVHRDLKPQNILI-----APPKRYLSLHASKNKF----- 856
+++ Q+ V HLH + IVHRD+KP+N+L P + Y NK
Sbjct: 166 ---HIIIQVAEAVKHLHDVCGIVHRDIKPENLLFQPIEYLPSQNYTPPSLEPNKLDEGMF 222
Query: 857 ----------RVLISDFGLCKKLEIDESSFRTNNFNNPTGTSGWRAPEIISGEVSLSESF 906
R+LI+DFG K + +++ P GT G+ APEI++ E+
Sbjct: 223 LEGIGAGGIGRILIADFGFSKVVWNSKTA-------TPCGTVGYAAPEIVNDEL------ 269
Query: 907 AXXXXXXXXXXXXXXLDVNHMDLVTKKRLTRAVDIFSLGCIFYYVLSKGEHPFGDRILRE 966
++ VD++++GC+ + +L G PF D +++
Sbjct: 270 ----------------------------YSKNVDMWAMGCVLHTMLC-GFPPFFDENIKD 300
Query: 967 --ANILKGDYRLDGIKKSIQERSVCIEAADLIKSMLEQNPLLRPASDEILKHPLFWGVSK 1024
+ ++ G++ S + A DLI +L +P R + +HP G SK
Sbjct: 301 LASKVVNGEFEF----LSPWWDDISDSAKDLITHLLTVDPRERYDIHQFFQHPWIKGESK 356
Query: 1025 KLE 1027
E
Sbjct: 357 MPE 359
>Hs9966875 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-Hand protein
superfamily
Length = 357
Score = 67.8 bits (164), Expect = 1e-10
Identities = 65/266 (24%), Positives = 113/266 (42%), Gaps = 66/266 (24%)
Query: 760 HPNVIRYYFSESTEKFMYIAVELCSAS--LEDVIEGSKGLAKNVAVQKNIDPINVLFQIT 817
H N++ + +Y+ ++L S + ++E K +K D ++ Q+
Sbjct: 78 HENIVALEDIYESPNHLYLVMQLVSGGELFDRIVE------KGFYTEK--DASTLIRQVL 129
Query: 818 SGVNHLHSMKIVHRDLKPQNILIAPPKRYLSLHASKNKFRVLISDFGLCKKLEIDESSFR 877
V +LH M IVHRDLKP+N+L ++ + +++ISDFGL K +
Sbjct: 130 DAVYYLHRMGIVHRDLKPENLL---------YYSQDEESKIMISDFGLSK------MEGK 174
Query: 878 TNNFNNPTGTSGWRAPEIISGEVSLSESFAXXXXXXXXXXXXXXLDVNHMDLVTKKRLTR 937
+ + GT G+ APE+++ +K ++
Sbjct: 175 GDVMSTACGTPGYVAPEVLA----------------------------------QKPYSK 200
Query: 938 AVDIFSLGCIFYYVLSKGEHPFGDRILRE--ANILKGDYRLDGIKKSIQERSVCIEAADL 995
AVD +S+G I Y +L G PF D + ILK +Y D S + A D
Sbjct: 201 AVDCWSIGVIAYILLC-GYPPFYDENDSKLFEQILKAEYEFD----SPYWDDISDSAKDF 255
Query: 996 IKSMLEQNPLLRPASDEILKHPLFWG 1021
I++++E++P R ++ +HP G
Sbjct: 256 IRNLMEKDPNKRYTCEQAARHPWIAG 281
>CE28650 [OUT] KOG0595 Serine/threonine-protein kinase involved in autophagy
Length = 288
Score = 67.8 bits (164), Expect = 1e-10
Identities = 77/335 (22%), Positives = 139/335 (40%), Gaps = 59/335 (17%)
Query: 693 MLDF--KEFEQEGHLKHLSISSRVLGYGSSGTVVFQG--KFQNRPVAVKRLLIDFYDIAS 748
M DF K+ + +++ ++G G+ G V F+G K + +A+KR+L +
Sbjct: 1 MPDFTNKQIILDEKYEYMDSVDAMIGMGAFGAV-FKGSLKDSSNSIAIKRMLK--VHVKE 57
Query: 749 KEIQLLSESDDHPNVIRYYFSESTEKFMYIAVELCSASLEDVIEGSKGLAKNVAVQKNID 808
E++++ E + V + F + +ELC L+ + +N++V+ ++
Sbjct: 58 SELKMIKELNSEYLVGVLDICNFDDFFCCLIMELCDCDLDHHM-------RNISVKGRLN 110
Query: 809 PIN---VLFQITSGVNHLHSMKIVHRDLKPQNILIAPPKRYLSLHASKNKFRVLISDFGL 865
P N +L I G L+ +KIVHRD+KPQNILI ASK I+DFG+
Sbjct: 111 PSNFRLLLDNIARGYKALYELKIVHRDIKPQNILIT------YTDASKQIACARITDFGI 164
Query: 866 CKKLEIDESSFRTNNFNNPTGTSGWRAPEIISGEVSLSESFAXXXXXXXXXXXXXXLDVN 925
+ L+ + N GT + APE+
Sbjct: 165 SRTLDNE-----GEELCNVAGTFYYMAPEV------------------------------ 189
Query: 926 HMDLVTKKRLTRAVDIFSLGCIFYYVLSKGEHPFGDRILREANILKGDYRLDGIKKSIQE 985
+L+ + VD++S+GC+ Y ++ GE PF + L + + D
Sbjct: 190 GANLLKTCQYDSKVDMWSIGCLLYQCVT-GEVPFDECSLCKLFLYVAGANFDAYDPPELP 248
Query: 986 RSVCIEAADLIKSMLEQNPLLRPASDEILKHPLFW 1020
+ E + +I+S+L+ + R + + W
Sbjct: 249 DELSQEVSGIIQSLLQLDTTQRCTPTQFYDKAINW 283
>CE22877 [D] KOG0575 Polo-like serine/threonine protein kinase
Length = 632
Score = 67.8 bits (164), Expect = 1e-10
Identities = 78/301 (25%), Positives = 125/301 (40%), Gaps = 79/301 (26%)
Query: 724 VFQGKFQNRPVAVKRLLIDFY--DIASKEIQLLSESDDHPNVIRYYFSESTEKFMYIAVE 781
+F GK V K LLI Y D ++E+Q+ + H NV++ Y + +YI +E
Sbjct: 61 LFAGK-----VVPKALLIKQYQRDKMAQEVQI-HRNLQHRNVVKLYHFFEDKSNVYITLE 114
Query: 782 LCSA-SLEDVIEGSKGLAKNVAVQKNIDPINVLFQITSGVNHLHSMKIVHRDLKPQNILI 840
LC SL ++ + K + + A +QI GV +LH++KIVHRDLK N+ +
Sbjct: 115 LCPRRSLMELHKRRKAVTEPEARY-------FTYQIVEGVLYLHNLKIVHRDLKLGNLFL 167
Query: 841 APPKRYLSLHASKNKFRVLISDFGLCKKLEIDESSFRTNNFNNPTGTSGWRAPEIISGEV 900
++ +V I DFGL + DE GT + APE+++
Sbjct: 168 ------------NDELQVKIGDFGLATTCDNDERK------KTLCGTPNYIAPEVLN--- 206
Query: 901 SLSESFAXXXXXXXXXXXXXXLDVNHMDLVTKKRLTRAVDIFSLGCIFYYVLSKGEHPFG 960
+ SF VD++++GCI Y+L G PF
Sbjct: 207 KIGHSF-------------------------------EVDLWAIGCIL-YILLFGHPPFE 234
Query: 961 DRILRE--ANILKGDYRLDGIKKSIQERSVCIEAADLIKSMLEQNPLLRPASDEILKHPL 1018
+ L E + I +Y + S A+ LI+ +L+ P RP + + +
Sbjct: 235 SKSLEETYSRIKNNNY--------VIPTSASAAASQLIRVLLDPVPSRRPNARAVCRDHF 286
Query: 1019 F 1019
F
Sbjct: 287 F 287
>At2g41860 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-Hand protein
superfamily
Length = 530
Score = 67.8 bits (164), Expect = 1e-10
Identities = 82/335 (24%), Positives = 129/335 (38%), Gaps = 85/335 (25%)
Query: 700 EQEGH-LKHLSISSRVLGYGSSGTVVFQGKFQNRPV-AVKRLL-------IDFYDIASKE 750
E GH +K R LG G G + + + A K +L ID D+ +E
Sbjct: 44 EPTGHEIKQKYKLGRELGRGEFGVTYLCTEIETGEIFACKSILKKKLKTSIDIEDV-KRE 102
Query: 751 IQLLSESDDHPNVIRYYFSESTEKFMYIAVELCSAS-LEDVIEGSKGLAKNVAVQKNIDP 809
++++ + +HPN++ + +K +++ +ELC L D I + A
Sbjct: 103 VEIMRQMPEHPNIVTLKETYEDDKAVHLVMELCEGGELFDRIVARGHYTERAAA------ 156
Query: 810 INVLFQITSGVNHLHSMKIVHRDLKPQNILIAPPKRYLSLHASKNKFRVLISDFGLCKKL 869
+V+ I V H ++HRDLKP+N L A K SL A DFGL
Sbjct: 157 -SVIKTIIEVVQMCHKHGVMHRDLKPENFLFANKKETASLKA---------IDFGLSVFF 206
Query: 870 EIDESSFRTNNFNNPTGTSGWRAPEIISGEVSLSESFAXXXXXXXXXXXXXXLDVNHMDL 929
+ E FN G+ + APE++
Sbjct: 207 KPGE------RFNEIVGSPYYMAPEVL--------------------------------- 227
Query: 930 VTKKRLTRAVDIFSLGCIFYYVL-------SKGEHPFGDRILREANILKGDYRLDGIKKS 982
++ + +DI+S G I Y +L ++ EH IL+ D++ D K
Sbjct: 228 --RRSYGQEIDIWSAGVILYILLCGVPPFWAETEHGVAKAILKSVI----DFKRDPWPK- 280
Query: 983 IQERSVCIEAADLIKSMLEQNPLLRPASDEILKHP 1017
V A DLIK ML +P R + ++L HP
Sbjct: 281 -----VSDNAKDLIKKMLHPDPRRRLTAQQVLDHP 310
>YNR047w [R] KOG0610 Putative serine/threonine protein kinase
Length = 893
Score = 67.4 bits (163), Expect = 1e-10
Identities = 90/340 (26%), Positives = 139/340 (40%), Gaps = 77/340 (22%)
Query: 713 RVLGYGSSGTV-VFQGKFQNRPVAVKRLLIDFYDIASKEIQLLSESD-----DHPNVIRY 766
R+LG G G V + + K NR A+K L D +K ++L+E + +HP ++
Sbjct: 500 RLLGQGDVGKVFLVREKKTNRVYALKVLSKDEMIKRNKIKRVLTEQEILATSNHPFIVTL 559
Query: 767 YFSESTEKFMYIAVELCSASLEDVIEGSKGLAKNVAVQKNIDPINVLF---QITSGVNHL 823
Y S +E ++Y+ +E C G A K I + F ++T+ + +L
Sbjct: 560 YHSFQSEDYLYLCMEYCMG-------GEFFRALQTRKTKCICEDDARFYASEVTAALEYL 612
Query: 824 HSMKIVHRDLKPQNILIAPPKRY------LSLHASKNKFRVLI-SDFGLCKKLEIDESSF 876
H + ++RDLKP+NIL+ LS+ A +K V+ S +I F
Sbjct: 613 HLLGFIYRDLKPENILLHQSGHIMLSDFDLSIQAKDSKVPVVKGSAQSTLVDTKICSDGF 672
Query: 877 RTNNFNNPTGTSGWRAPEIISGEVSLSESFAXXXXXXXXXXXXXXLDVNHMDLVTKKRLT 936
RTN+F GT + APE+I G H T
Sbjct: 673 RTNSF---VGTEEYIAPEVIRGN-------------------------GH---------T 695
Query: 937 RAVDIFSLGCIFYYVLSKGEHPFGDRILRE--ANILKGDYRLDGIKKSIQERSVCIEAAD 994
AVD ++LG + Y +L G PF E NILK + + D
Sbjct: 696 AAVDWWTLGILIYEMLF-GFTPFKGDNTNETFTNILKNEVSFP------NNNEISRTCKD 748
Query: 995 LIKSMLEQNPLLR----PASDEILKHPLFWGVSKKLEFLL 1030
LIK +L +N R + ++ KHP F KK+++ L
Sbjct: 749 LIKKLLTKNESKRLGCKMGAADVKKHPFF----KKVQWSL 784
>CE28479 [T] KOG0583 Serine/threonine protein kinase
Length = 822
Score = 67.4 bits (163), Expect = 1e-10
Identities = 86/314 (27%), Positives = 132/314 (41%), Gaps = 79/314 (25%)
Query: 713 RVLGYGSSGTV-VFQGKFQNRPVAVKRLLIDFYDIAS-----KEIQLLSESDDHPNVIRY 766
R +G G+ TV + + K VA+K + + D + +E++++ D HP++++
Sbjct: 20 RAIGKGNFATVRIARHKIAKTKVAIKSIDVSALDRENLIKLEREVKIVKVID-HPHIVKS 78
Query: 767 YFSESTEKFMYIAVELCSAS--LEDVIEGSKGLAKNVAVQKNIDPINVLFQITSGVNHLH 824
Y + +YI E CS+ E +IE + +A+NVA + + S V +LH
Sbjct: 79 YEIMRVDNMLYIVSEYCSSGELYETLIEKGR-VAENVARKW-------FSETASAVAYLH 130
Query: 825 SMKIVHRDLKPQNILIAPPKRYLSLHASKNKFRVLISDFGLCKKLEIDESSFRTNN--FN 882
S IVHRDLK +NIL+ KN + I DFG S+F+T + N
Sbjct: 131 SQGIVHRDLKAENILL-----------GKNS-NIKIIDFGF--------SNFQTGDQLLN 170
Query: 883 NPTGTSGWRAPEIISGEVSLSESFAXXXXXXXXXXXXXXLDVNHMDLVTKKRLTRAVDIF 942
G+ + APE++ G N D DI+
Sbjct: 171 TWCGSPPYAAPELLLG--------------------------NSYD-------GMKADIW 197
Query: 943 SLGCIFYYVLSKGEHPFGDRILREANILKGDYRLDGIKKSIQERSVCIEAADLIKSMLEQ 1002
S+G + Y+L G PF N LK L G+ K V +E AD I+ ML
Sbjct: 198 SMG-VLLYILVAGGFPFPS---DSVNKLKRSV-LSGLVKI--PYWVSVECADFIRKMLVL 250
Query: 1003 NPLLRPASDEILKH 1016
NP R +L+H
Sbjct: 251 NPGKRYTIQNVLQH 264
>CE21401 [G] KOG0658 Glycogen synthase kinase-3
Length = 362
Score = 67.4 bits (163), Expect = 1e-10
Identities = 63/203 (31%), Positives = 104/203 (51%), Gaps = 35/203 (17%)
Query: 713 RVLGYGSSGTVVFQGKFQ--NRPVAVKRLLIDFYDIASKEIQLLSESDDHPNVIR--YYF 768
+V+G GS G VVF K N VA+K++L D ++E+Q++ + + HPN+++ Y+F
Sbjct: 40 KVIGNGSFG-VVFLAKLSTTNEMVAIKKVLQD-KRFKNRELQIMRKLN-HPNIVKLKYFF 96
Query: 769 SESTEKFMYIAVELCSASLEDVIEGSKGLAKNVAVQKNIDPINV----LFQITSGVNHLH 824
S EK + + L LE V E +A++ + Q+ P+ ++Q+ + ++H
Sbjct: 97 YSSGEKKDELYLNLI---LEYVPETVYRVARHYSKQRQQIPMIYVKLYMYQLLRSLAYIH 153
Query: 825 SMKIVHRDLKPQNILIAPPKRYLSLHASKNKFRVLISDFGLCKKLEIDES--SFRTNNFN 882
S+ I HRD+KPQN+LI P L L DFG K L +E S+ + +
Sbjct: 154 SIGICHRDIKPQNLLIDPESGVLKL-----------CDFGSAKYLVRNEPNVSYICSRY- 201
Query: 883 NPTGTSGWRAPEIISGEVSLSES 905
+RAPE+I G + + S
Sbjct: 202 -------YRAPELIFGATNYTNS 217
>SPAC1687.15 [G] KOG0658 Glycogen synthase kinase-3
Length = 387
Score = 67.0 bits (162), Expect = 2e-10
Identities = 84/349 (24%), Positives = 141/349 (40%), Gaps = 89/349 (25%)
Query: 703 GHLKHLSI-SSRVLGYGSSGTVVFQGKFQN-RPVAVKRLLIDFYDIASKEIQLLSESDDH 760
G +K LS SS+V+G GS G V+ ++ A+KR+L D ++E+Q++ H
Sbjct: 25 GEVKQLSYTSSKVVGSGSFGVVMQVHLIESDSKAAIKRVLQD-KRFKNRELQIMRIMK-H 82
Query: 761 PNV---IRYYFS---ESTEKFMYIAVELCSASLEDVIEGSKGLAKNVAVQKNIDPINVLF 814
PN+ I YY++ S E ++ + +E E + S+ + ++ ++
Sbjct: 83 PNIVDLIAYYYTTGDNSDEVYLNLVLEFMP---ETIYRASRLYTRQKLSMPMLEVKLYIY 139
Query: 815 QITSGVNHLHSMKIVHRDLKPQNILIAPPKRYLSLHASKNKFRVLISDFGLCKKLEIDES 874
Q+ + ++H+ I HRD+KPQN+L+ P L L DFG K L E
Sbjct: 140 QLLRSLAYIHASGICHRDIKPQNLLLDPENGILKL-----------CDFGSAKILVAGEP 188
Query: 875 --SFRTNNFNNPTGTSGWRAPEIISGEVSLSESFAXXXXXXXXXXXXXXLDVNHMDLVTK 932
S+ + + +RAPE+I G
Sbjct: 189 NVSYICSRY--------YRAPELIFGATD------------------------------- 209
Query: 933 KRLTRAVDIFSLGCIFY-----YVLSKGEHPFGDRI-------------LREANILKGDY 974
T A+DI+S GC+ + L GE + ++ N ++
Sbjct: 210 --YTHAIDIWSTGCVMAELMLGHPLFPGESGIDQLVEIIKILGTPSREQIKTMNPNYMEH 267
Query: 975 RLDGIK----KSIQERSVCIEAADLIKSMLEQNPLLRPASDEILKHPLF 1019
R I+ + RSV ++A DL+ ML+ P R + E + HP F
Sbjct: 268 RFPQIRPQPLSRVFSRSVPLDALDLLSKMLQYTPTDRLTAAEAMCHPFF 316
>At4g18710 [G] KOG0658 Glycogen synthase kinase-3
Length = 380
Score = 67.0 bits (162), Expect = 2e-10
Identities = 88/342 (25%), Positives = 144/342 (41%), Gaps = 90/342 (26%)
Query: 710 ISSRVLGYGSSGTVVFQGKF--QNRPVAVKRLLIDFYDIASKEIQLLSESDDHPNVI--R 765
++ RV+G GS G +VFQ K VA+K++L D ++E+QL+ D HPNV+ +
Sbjct: 41 MAERVVGTGSFG-IVFQAKCLETGETVAIKKVLQD-RRYKNRELQLMRVMD-HPNVVCLK 97
Query: 766 YYFSESTEK---FMYIAVELCSASLEDVIEGSKGLAKNVAVQKNIDPINVLFQITSGVNH 822
+ F +T K F+ + +E SL V++ + + + + ++QI G+ +
Sbjct: 98 HCFFSTTSKDELFLNLVMEYVPESLYRVLKHYSSANQRMPL---VYVKLYMYQIFRGLAY 154
Query: 823 LHSMK-IVHRDLKPQNILIAPPKRYLSLHASKNKFRVLISDFGLCKKLEIDES--SFRTN 879
+H++ + HRDLKPQN+L+ P +V I DFG K+L E+ S+ +
Sbjct: 155 IHNVAGVCHRDLKPQNLLVDPLTH-----------QVKICDFGSAKQLVKGEANISYICS 203
Query: 880 NFNNPTGTSGWRAPEIISGEVSLSESFAXXXXXXXXXXXXXXLDVNHMDLVTKKRLTRAV 939
F +RAPE+I G T ++
Sbjct: 204 RF--------YRAPELIFGAT---------------------------------EYTTSI 222
Query: 940 DIFSLGCIFYYV-----LSKGEHPFGDRI-------------LREANILKGDYRLDGIK- 980
DI+S GC+ + L GE+ + +R N D+R IK
Sbjct: 223 DIWSAGCVLAELLLGQPLFPGENAVDQLVEIIKVLGTPTREEIRCMNPHYTDFRFPQIKA 282
Query: 981 ---KSIQERSVCIEAADLIKSMLEQNPLLRPASDEILKHPLF 1019
I + + EA D +L+ +P LR + E HP F
Sbjct: 283 HPWHKIFHKRMPPEAIDFASRLLQYSPSLRCTALEACAHPFF 324
>Hs8393810_1 [T] KOG0587 Traf2- and Nck-interacting kinase and related germinal
center kinase (GCK) family protein kinases
Length = 336
Score = 67.0 bits (162), Expect = 2e-10
Identities = 54/206 (26%), Positives = 96/206 (46%), Gaps = 33/206 (16%)
Query: 712 SRVLGYGSSGTVVFQGKFQNRPVAVKRLLIDFYDIASK---EIQLLSESDDHPNVIRYYF 768
+ +G G+ G V +N A ++L +DI + E +L DHPNV+R+Y
Sbjct: 24 TETIGKGTYGKVFKVLNKKNGQKAAVKILDPIHDIDEEIEAEYNILKALSDHPNVVRFYG 83
Query: 769 -----SESTEKFMYIAVELCSA-SLEDVIEGSKGLAKNVAVQKNIDPI--NVLFQITSGV 820
+ +++ +ELCS S+ D+++G + ++ +P+ +L + G+
Sbjct: 84 IYFKKDKVNGDKLWLVLELCSGGSVTDLVKGFLKRGERMS-----EPLIAYILHEALMGL 138
Query: 821 NHLHSMKIVHRDLKPQNILIAPPKRYLSLHASKNKFRVLISDFGLCKKLEIDESSFRTNN 880
HLH+ K +HRD+K NIL+ + V + DFG+ +L + +
Sbjct: 139 QHLHNNKTIHRDVKGNNILLT------------TEGGVKLVDFGVSAQL-----TSTRHR 181
Query: 881 FNNPTGTSGWRAPEIISGEVSLSESF 906
N GT W APE+I+ E L ++
Sbjct: 182 RNTSVGTPFWMAPEVIACEQQLDTTY 207
>Hs20544910_1 [T] KOG0587 Traf2- and Nck-interacting kinase and related germinal
center kinase (GCK) family protein kinases
Length = 336
Score = 67.0 bits (162), Expect = 2e-10
Identities = 54/206 (26%), Positives = 96/206 (46%), Gaps = 33/206 (16%)
Query: 712 SRVLGYGSSGTVVFQGKFQNRPVAVKRLLIDFYDIASK---EIQLLSESDDHPNVIRYYF 768
+ +G G+ G V +N A ++L +DI + E +L DHPNV+R+Y
Sbjct: 24 TETIGKGTYGKVFKVLNKKNGQKAAVKILDPIHDIDEEIEAEYNILKALSDHPNVVRFYG 83
Query: 769 -----SESTEKFMYIAVELCSA-SLEDVIEGSKGLAKNVAVQKNIDPI--NVLFQITSGV 820
+ +++ +ELCS S+ D+++G + ++ +P+ +L + G+
Sbjct: 84 IYFKKDKVNGDKLWLVLELCSGGSVTDLVKGFLKRGERMS-----EPLIAYILHEALMGL 138
Query: 821 NHLHSMKIVHRDLKPQNILIAPPKRYLSLHASKNKFRVLISDFGLCKKLEIDESSFRTNN 880
HLH+ K +HRD+K NIL+ + V + DFG+ +L + +
Sbjct: 139 QHLHNNKTIHRDVKGNNILLT------------TEGGVKLVDFGVSAQL-----TSTRHR 181
Query: 881 FNNPTGTSGWRAPEIISGEVSLSESF 906
N GT W APE+I+ E L ++
Sbjct: 182 RNTSVGTPFWMAPEVIACEQQLDTTY 207
>SPAC9G1.02 [T] KOG4645 MAPKKK (MAP kinase kinase kinase) SSK2 and related
serine/threonine protein kinases
Length = 1401
Score = 66.6 bits (161), Expect = 2e-10
Identities = 90/362 (24%), Positives = 140/362 (37%), Gaps = 86/362 (23%)
Query: 691 GPMLDFKEFEQEGHLKHLSISSRVLGYGSSGTVVFQGKFQNRPVAVKRLLIDFYDIASKE 750
G +LD F +K S S + G V G F + V D +A KE
Sbjct: 1010 GHVLDDSVFRNRDFIKLASSFSNITIRWQQGHFVRSGMFGDVYTGVNMETGDL--LAVKE 1067
Query: 751 IQL------------------LSESDDHPNVIRYYFSESTEKFMYIAVELCSA-SLEDVI 791
I+L + E +HPNV+ YY E + +YI +E C SL D+
Sbjct: 1068 IKLQDSRTFRSTVDQIHNEMTVLERLNHPNVVTYYGVEVHREKVYIFMEFCQGGSLADL- 1126
Query: 792 EGSKGLAKNVAVQKNIDPINVLFQITSGVNHLHSMKIVHRDLKPQNILIAPPKRYLSLHA 851
LA +N+ + V+ Q+ G+ ++HS I+HRD+KP NIL+
Sbjct: 1127 -----LAHGRIEDENVLKVYVV-QLLEGLAYIHSQHILHRDIKPANILL----------- 1169
Query: 852 SKNKFRVLISDFGLCKKL------EIDESSFRTNNFNNPTGTSGWRAPEIISGEVSLSES 905
++ + SDFG + E+ + + GT + APEII G
Sbjct: 1170 -DHRGMIKYSDFGSALYVSPPTDPEVRYEDIQP-ELQHLAGTPMYMAPEIILG------- 1220
Query: 906 FAXXXXXXXXXXXXXXLDVNHMDLVTKKRLTRAVDIFSLGCIFYYVLSKGEHPFGDRILR 965
TKK A+DI+SLGC+ +++ G P+ +
Sbjct: 1221 -------------------------TKKGDFGAMDIWSLGCVILEMMT-GSTPWSEMDNE 1254
Query: 966 EANILKGDYRLDGIKKSI--QERSVCIEAADLIKSMLEQNPLLRPASDEILKHPLFWGVS 1023
A + Y + + Q + A D I+ E++P RP + ++L HP
Sbjct: 1255 WAIM----YHVAAMHTPSIPQNEKISSLARDFIEQCFERDPEQRPRAVDLLTHPWITDFR 1310
Query: 1024 KK 1025
KK
Sbjct: 1311 KK 1312
>CE08727 [G] KOG0658 Glycogen synthase kinase-3
Length = 367
Score = 66.6 bits (161), Expect = 2e-10
Identities = 80/310 (25%), Positives = 126/310 (39%), Gaps = 36/310 (11%)
Query: 713 RVLGYGSSGTVVFQGKFQN-RPVAVKRLLIDFYDIASKEIQLLSESDDHPNVIR--YYFS 769
+++G GS G V +N P+A+K++ +D S+E+ ++ E D HPN+IR YY+
Sbjct: 41 QLIGTGSFGAVYKAVLRENDEPIAIKKIKVDDR-FKSRELTIMHEMD-HPNIIRLLYYYV 98
Query: 770 ESTEKFMYIAVELCSASLEDVIEGSKGLAKNVAVQKNIDPINVLFQITSGVNHLHSMKIV 829
E + +E L V + A N +FQ+ G+ LH IV
Sbjct: 99 MQQENCLNFVMEFMPKDLAYV---HRQFAHNDKQMPAYSIKLYMFQLLRGIGFLHLHNIV 155
Query: 830 HRDLKPQNILIAPPKRYLSLHASKNKFRVLISDFGLCKKLEIDESSFRTNNFNNPTGTSG 889
HRD+KP+N+L+ L I DFG K+LE +E + +
Sbjct: 156 HRDIKPKNLLVDESNGILK-----------ICDFGSAKRLEKNEPNI------TYICSRY 198
Query: 890 WRAPEIISGEVSLSESFAXXXXXXXXXXXXXXLDVNHMDLVTKKRLTRAVDIFSLGCIFY 949
+RAPE+I G + S + D AVDI +L +
Sbjct: 199 YRAPELIFGSKNYDTSIDTWSVGTVVGELLHNSPIFLAD--------SAVDILALQIKAF 250
Query: 950 YVLSKGEHPFGDRILREANILKGDYRLDGIKKSIQERSVCIEAADLIKSMLEQNPLLRPA 1009
SK + +I GI+K I R + + +L+ S+++ +P LR
Sbjct: 251 GTPSKED--MAKWNYEYVHIPYDTITGVGIQKFI-GRKLSLSTLELLNSLMKMDPKLRIK 307
Query: 1010 SDEILKHPLF 1019
E L P F
Sbjct: 308 PYEALTLPYF 317
>At1g49580 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-Hand protein
superfamily
Length = 606
Score = 66.6 bits (161), Expect = 2e-10
Identities = 75/300 (25%), Positives = 123/300 (41%), Gaps = 68/300 (22%)
Query: 726 QGKFQNRPVAVKRL-------LIDFYDIASKEIQLLSESDDHPNVIRYYFSESTEKFMYI 778
+G+ + + VAVK + I D+ +E+++L H N++++Y + +YI
Sbjct: 171 KGELKGQVVAVKIIPKSKMTTAIAIEDVR-REVKILQALSGHKNLVQFYDAFEDNANVYI 229
Query: 779 AVELCSAS-LEDVIEGSKGLAKNVAVQKNIDPINVLFQITSGVNHLHSMKIVHRDLKPQN 837
A+ELC L D I LA+ +N D V+ QI + V H +VHRDLKP+N
Sbjct: 230 AMELCEGGELLDRI-----LARGGKYSEN-DAKPVIIQILNVVAFCHFQGVVHRDLKPEN 283
Query: 838 ILIAPPKRYLSLHASKNKFRVLISDFGLCKKLEIDESSFRTNNFNNPTGTSGWRAPEIIS 897
L + L A DFGL + DE N+ G++ + APE++
Sbjct: 284 FLYTSKEENSQLKA---------IDFGLSDFVRPDE------RLNDIVGSAYYVAPEVL- 327
Query: 898 GEVSLSESFAXXXXXXXXXXXXXXLDVNHMDLVTKKRLTRAVDIFSLGCIFYYVLSKGEH 957
+ T D++S+G I Y +L G
Sbjct: 328 ----------------------------------HRSYTTEADVWSIGVIAYILLC-GSR 352
Query: 958 PFGDRILREANILKGDYRLDGIKKSIQERSVCIEAADLIKSMLEQNPLLRPASDEILKHP 1017
PF R E+ I + + D + +A D +K +L ++P R ++ + L HP
Sbjct: 353 PFWAR--TESGIFRAVLKADPSFDEPPWPFLSSDAKDFVKRLLFKDPRRRMSASQALMHP 410
>At1g35670 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-Hand protein
superfamily
Length = 495
Score = 66.6 bits (161), Expect = 2e-10
Identities = 84/329 (25%), Positives = 136/329 (40%), Gaps = 76/329 (23%)
Query: 701 QEGHLKHLSISSRVLGYGSSGTVVF------QGKFQNRPVAVKRLLI-DFYDIASKEIQL 753
Q L+ + + LG G GT + + + ++L+ + Y+ +EIQ+
Sbjct: 18 QTPRLRDHYLLGKKLGQGQFGTTYLCTEKSTSANYACKSIPKRKLVCREDYEDVWREIQI 77
Query: 754 LSESDDHPNVIRYYFSESTEKFMYIAVELCSAS-LEDVIEGSKGLAKNVAVQKNIDPINV 812
+ +HPNV+R + F++I +E+C L D I ++ AV+ +
Sbjct: 78 MHHLSEHPNVVRIKGTYEDSVFVHIVMEVCEGGELFDRIVSKGHFSEREAVK-------L 130
Query: 813 LFQITSGVNHLHSMKIVHRDLKPQNILIAPPKRYLSLHASKNKFRVLISDFGLCKKLEID 872
+ I V HS+ ++HRDLKP+N L PK L A +DFGL +
Sbjct: 131 IKTILGVVEACHSLGVMHRDLKPENFLFDSPKDDAKLKA---------TDFGLSVFYKPG 181
Query: 873 ESSFRTNNFNNPTGTSGWRAPEIISGEVSLSESFAXXXXXXXXXXXXXXLDVNHMDLVTK 932
+ + + G+ + APE++ K
Sbjct: 182 QYLY------DVVGSPYYVAPEVL-----------------------------------K 200
Query: 933 KRLTRAVDIFSLGCIFYYVLSKGEHPF----GDRILREANILKGDYRLDGIKKSIQERSV 988
K +D++S G I Y +LS G PF I R+ IL+G +LD KS ++
Sbjct: 201 KCYGPEIDVWSAGVILYILLS-GVPPFWAETESGIFRQ--ILQG--KLD--FKSDPWPTI 253
Query: 989 CIEAADLIKSMLEQNPLLRPASDEILKHP 1017
A DLI MLE++P R ++ E L HP
Sbjct: 254 SEAAKDLIYKMLERSPKKRISAHEALCHP 282
>At1g12680 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-Hand protein
superfamily
Length = 470
Score = 66.6 bits (161), Expect = 2e-10
Identities = 65/314 (20%), Positives = 125/314 (39%), Gaps = 74/314 (23%)
Query: 710 ISSRVLGYGSSGTVVFQGKFQNRPVAVKRLLIDFYDIASKEIQLLSESDDHPNVIRYYFS 769
+ R +G G G+V +N + L + +E++++ HP V+ +
Sbjct: 108 VFGRNIGKGKFGSVRICKSRKNGTEFACKTLKKGEETVHREVEIMQHLSGHPRVVTLHAV 167
Query: 770 ESTEKFMYIAVELCSAS--LEDVIEGSKGLAKNVAVQKNIDPINVLFQITSGVNHLHSMK 827
++ +ELCS ++ +++ + + A N+ + +N+ H M
Sbjct: 168 YEESDCFHLVMELCSGGRLIDQMVKVGRYSEQRAA--------NIFKDLMLVINYCHEMG 219
Query: 828 IVHRDLKPQNILIAPPKRYLSLHASKNKFRVLISDFGLCKKLEIDESSFRTNNFNNPTGT 887
+VHRD+KP+NIL+ ++ ++DFGL ++ + + G+
Sbjct: 220 VVHRDIKPENILLTAAG------------KIQLADFGLAMRIA------KGQTLSGLAGS 261
Query: 888 SGWRAPEIISGEVSLSESFAXXXXXXXXXXXXXXLDVNHMDLVTKKRLTRAVDIFSLGCI 947
+ APE++S + + VD++S G +
Sbjct: 262 PAYVAPEVLS-----------------------------------ENYSEKVDVWSAGVL 286
Query: 948 FYYVLSKGEHPFG----DRILREANILKGDYRLDGIKKSIQERSVCIEAADLIKSMLEQN 1003
Y +LS G PF D I +K D+ G+ +S+ + A DL+ ML +
Sbjct: 287 LYALLS-GVLPFKGDSLDAIFEAIKNVKLDFN-TGVWESVSK-----PARDLLARMLTRE 339
Query: 1004 PLLRPASDEILKHP 1017
R +DE+L+HP
Sbjct: 340 ESARITADEVLRHP 353
>YGL179c [T] KOG0585 Ca2+/calmodulin-dependent protein kinase kinase beta and
related serine/threonine protein kinases
Length = 560
Score = 66.2 bits (160), Expect = 3e-10
Identities = 90/388 (23%), Positives = 155/388 (39%), Gaps = 81/388 (20%)
Query: 712 SRVLGYGSSGTVVFQGKFQNRPVAVKRLLIDFYDIASKEIQLLSESDDHPNVIRYY--FS 769
+R LG G+ + +F+ R +L ++ + ++EI+++ H NV+ Y +
Sbjct: 67 ARDLGTGALVAIKILNRFEKRSGYSLQLKVENPRV-NQEIEVMKRCH-HENVVELYEILN 124
Query: 770 ESTEKFMYIAVELCSASLEDVIEGSKGLAKNVAVQKNIDPINVLFQ--------ITSGVN 821
+ +Y+ +E CS K +N K + P + FQ + SG+
Sbjct: 125 DPESTKVYLVLEYCSRG------PVKWCPENKMEIKAVGPSILTFQQSRKVVLDVVSGLE 178
Query: 822 HLHSMKIVHRDLKPQNILIAPPKRYLSLHASKNKFRVLISDFGLCKKLEIDESSFRTNN- 880
+LHS I HRD+KP N+LI+ + V ISDFG+ ++ ++++
Sbjct: 179 YLHSQGITHRDIKPSNLLIS------------SNGTVKISDFGVAMSTATGSTNIQSSHE 226
Query: 881 ---FNNPTGTSGWRAPEIISGEVSLSESFAXXXXXXXXXXXXXXLDVNHMDLVTKKRLTR 937
+ GT + APE+ S E S +
Sbjct: 227 QLLKSRALGTPAFFAPELCSTEKEYS-------------------------------CSS 255
Query: 938 AVDIFSLGCIFYYVL--------SKGEHPFGDRILREANILKGDYRLDGIKKSIQERSVC 989
A+DI+SLG Y +L + G F I + + L+G I
Sbjct: 256 AIDIWSLGVTIYCLLFGKLPFNANSGLELFDSIINKPLEFPSYEEMLNGATSGITMEEY- 314
Query: 990 IEAADLIKSMLEQNPLLRPASDEILKHPLF--WGVSKKLEFLLKVSDRFEVERRDPPSPL 1047
+A DL+K +L+++P R +I HP +G S L + E++ P S
Sbjct: 315 TDAKDLLKKLLQKDPDKRIKLADIKVHPFMCHYGKSDAASVLTNLETFHELKVSPPSS-- 372
Query: 1048 LLKLEEVSAKVITTGDWSMKFDAVFMEN 1075
++E VS V ++ D+V+MEN
Sbjct: 373 CKRVELVSLPVNSS---FASLDSVYMEN 397
>SPBC1861.09 [R] KOG0610 Putative serine/threonine protein kinase
Length = 526
Score = 66.2 bits (160), Expect = 3e-10
Identities = 94/372 (25%), Positives = 147/372 (39%), Gaps = 108/372 (29%)
Query: 713 RVLGYGSSGTV----------VFQGKFQNRPVAVKRLLIDFYDIASKEIQLLSESDDHPN 762
R+LG G G V +F K N+ +KR ++ +A +EI S+ HP
Sbjct: 159 RLLGQGDVGKVYLVRQKSNHRLFAMKILNKREMIKRHKVNRV-LAEQEILTKSK---HPF 214
Query: 763 VIRYYFSESTEKFMYIAVELCSASLEDVIEGSKGLAKNVAVQKNIDPINVLFQITSGVNH 822
++ Y S + ++Y+ +E C+ + L K++ +K D ++T+ + +
Sbjct: 215 IVTLYHSFQSRDYLYLCMEYCAGG--EFFRALHSLPKHILPEK--DACFYAAEVTAALEY 270
Query: 823 LHSMKIVHRDLKPQNILIAPPKRYLSLHASKNKFRVLISDFGLCKKLEIDE--------- 873
LH M ++RDLKP+NIL LH S + +++SDF L K + I
Sbjct: 271 LHLMGFIYRDLKPENIL---------LHQSGH---IMLSDFDLSKPISIVTHPTVVLPKH 318
Query: 874 ----------------SSFRTNNFNNPTGTSGWRAPEIISGEVSLSESFAXXXXXXXXXX 917
S+FRTN+F GT + APE+I
Sbjct: 319 STFSQEKPALDTNSYFSNFRTNSF---VGTEEYIAPEVIR-------------------- 355
Query: 918 XXXXLDVNHMDLVTKKRLTRAVDIFSLGCIFYYVLSKGEHPF--GDRILREANILKGDYR 975
H T AVD ++LG IF Y + G PF +R +NIL D
Sbjct: 356 -----SCGH---------TVAVDWWTLG-IFIYEILYGTTPFKGKNRHATFSNILYSDVS 400
Query: 976 LDGIKKSIQERSVCIEAADLIKSMLEQNPLLRPAS----DEILKHPLF----WGV--SKK 1025
+ S C LI+ +L ++ R S +I +HP F W + S K
Sbjct: 401 FPEYHGAPNVSSTC---KSLIRRLLVKDESKRCGSVAGASDIKQHPFFRHIQWALLRSMK 457
Query: 1026 LEFLLKVSDRFE 1037
+ K+ D E
Sbjct: 458 PPIIPKIEDGME 469
>Hs21361643 [T] KOG4717 Serine/threonine protein kinase
Length = 765
Score = 66.2 bits (160), Expect = 3e-10
Identities = 65/265 (24%), Positives = 112/265 (41%), Gaps = 66/265 (24%)
Query: 760 HPNVIRYYFSESTEKFMYIAVELCSAS--LEDVIEGSKGLAKNVAVQKNIDPINVLFQIT 817
HPN++R Y T+ +Y+ +EL + +++ +GL +++ P QI
Sbjct: 72 HPNIVRLYEVIDTQTKLYLILELGDEGDMFDYIMKHEEGLNEDL-------PKKYFAQIV 124
Query: 818 SGVNHLHSMKIVHRDLKPQNILIAPPKRYLSLHASKNKFRVLISDFGLCKKLEIDESSFR 877
+++ H + +VHRDLKP+N++ + + V ++DFG K + +
Sbjct: 125 HAISYCHKLHVVHRDLKPENVVF-----------FEKQGLVKLTDFGFSNKFQPGK---- 169
Query: 878 TNNFNNPTGTSGWRAPEIISGEVSLSESFAXXXXXXXXXXXXXXLDVNHMDLVTKKRLTR 937
G+ + APEI+ G+ +
Sbjct: 170 --KLTTSCGSLAYSAPEILLGD---------------------------------EYDAP 194
Query: 938 AVDIFSLGCIFYYVLSKGEHPFGDRILREANILKGDYRLDGIKKSIQERSVCIEAADLIK 997
AVDI+SLG I ++L G+ PF +EAN + + K ++ V E DLI
Sbjct: 195 AVDIWSLGVIL-FMLVCGQPPF-----QEANDSETLTMIMDCKYTVPSH-VSKECKDLIT 247
Query: 998 SMLEQNPLLRPASDEILKHPLFWGV 1022
ML+++P R + +EI HP GV
Sbjct: 248 RMLQRDPKRRASLEEIENHPWLQGV 272
>Hs20149547 [T] KOG0603 Ribosomal protein S6 kinase
Length = 735
Score = 66.2 bits (160), Expect = 3e-10
Identities = 94/349 (26%), Positives = 134/349 (37%), Gaps = 80/349 (22%)
Query: 687 LDDDG----PMLDFKEFEQEGHLKHLSISS-----RVLGYGS-SGTVVFQGKFQNRPVAV 736
++DDG P Q+ H K+L S +G GS S K N AV
Sbjct: 387 MEDDGKPRAPQAPLHSVVQQLHGKNLVFSDGYVVKETIGVGSYSECKRCVHKATNMEYAV 446
Query: 737 KRLLIDFYDIASKEIQLLSESDDHPNVIRYYFSESTEKFMYIAVELC-SASLEDVIEGSK 795
K + D S+EI++L HPN+I K +Y+ EL L D I K
Sbjct: 447 KVIDKSKRD-PSEEIEILLRYGQHPNIITLKDVYDDGKHVYLVTELMRGGELLDKILRQK 505
Query: 796 GLAKNVAVQKNIDPINVLFQITSGVNHLHSMKIVHRDLKPQNILIAPPKRYLSLHASKNK 855
++ A VL I V +LHS +VHRDLKP NIL + S N
Sbjct: 506 FFSEREASF-------VLHTIGKTVEYLHSQGVVHRDLKPSNILY--------VDESGNP 550
Query: 856 FRVLISDFGLCKKLEIDESSFRTNNFNNPTGTSGWRAPEIISGEVSLSESFAXXXXXXXX 915
+ I DFG K+L + T P T+ + APE++
Sbjct: 551 ECLRICDFGFAKQLRAENGLLMT-----PCYTANFVAPEVLK------------------ 587
Query: 916 XXXXXXLDVNHMDLVTKKRLTRAVDIFSLGCIFYYVLSKGEHPFG-------DRILREAN 968
++ DI+SLG + Y +L+ G PF + IL
Sbjct: 588 ----------------RQGYDEGCDIWSLGILLYTMLA-GYTPFANGPSDTPEEIL--TR 628
Query: 969 ILKGDYRLDGIKKSIQERSVCIEAADLIKSMLEQNPLLRPASDEILKHP 1017
I G + L G + +V A DL+ ML +P R + ++L+HP
Sbjct: 629 IGSGKFTLSGGNWN----TVSETAKDLVSKMLHVDPHQRLTAKQVLQHP 673
Score = 51.2 bits (121), Expect = 9e-06
Identities = 50/194 (25%), Positives = 92/194 (46%), Gaps = 33/194 (17%)
Query: 713 RVLGYGSSGTVVFQGKFQNRPVA--------VKRLLIDFYD-IASKEIQLLSESDDHPNV 763
+VLG GS G V K RP + +K+ + D + +K + + +HP V
Sbjct: 66 KVLGQGSFGKVFLVRKV-TRPDSGHLYAMKVLKKATLKVRDRVRTKMERDILADVNHPFV 124
Query: 764 IRYYFSESTEKFMYIAVELCSASLEDVIEGSKGLAKNVAVQKNIDPINVLFQITSGVNHL 823
++ +++ TE +Y+ ++ + L+K V + D L ++ G++HL
Sbjct: 125 VKLHYAFQTEGKLYLILDFLRGG-----DLFTRLSKEVMFTEE-DVKFYLAELALGLDHL 178
Query: 824 HSMKIVHRDLKPQNILIAPPKRYLSLHASKNKFRVLISDFGLCKKLEIDESSFRTNNFNN 883
HS+ I++RDLKP+NIL+ + + ++DFGL K E + + +F
Sbjct: 179 HSLGIIYRDLKPENILL------------DEEGHIKLTDFGLSK--EAIDHEKKAYSF-- 222
Query: 884 PTGTSGWRAPEIIS 897
GT + APE+++
Sbjct: 223 -CGTVEYMAPEVVN 235
>At3g29160 [T] KOG0583 Serine/threonine protein kinase
Length = 512
Score = 65.9 bits (159), Expect = 4e-10
Identities = 86/317 (27%), Positives = 127/317 (39%), Gaps = 78/317 (24%)
Query: 713 RVLGYGSSGTV-VFQGKFQNRPVAVKRLL------IDFYDIASKEIQLLSESDDHPNVIR 765
+ LG GS G V + + VA+K L ++ + +EI++L HP++IR
Sbjct: 24 KTLGIGSFGKVKIAEHVVTGHKVAIKILNRRKIKNMEMEEKVRREIKIL-RLFMHPHIIR 82
Query: 766 YYFSESTEKFMYIAVELC-SASLEDVIEGSKGLAKNVAVQKNIDPINVLFQITSGVNHLH 824
Y T +Y+ +E S L D I L ++ A N QI SGV + H
Sbjct: 83 QYEVIETTSDIYVVMEYVKSGELFDYIVEKGRLQEDEAR-------NFFQQIISGVEYCH 135
Query: 825 SMKIVHRDLKPQNILIAPPKRYLSLHASKNKFRVLISDFGLCKKLEIDESSFRTNNFNNP 884
+VHRDLKP+N+L+ ++ + I+DFGL + D +T+
Sbjct: 136 RNMVVHRDLKPENLLL------------DSRCNIKIADFGLSNVMR-DGHFLKTS----- 177
Query: 885 TGTSGWRAPEIISGEVSLSESFAXXXXXXXXXXXXXXLDVNHMDLVTKKRLTRAVDIFSL 944
G+ + APE+ISG++ VD++S
Sbjct: 178 CGSPNYAAPEVISGKLYAGPE---------------------------------VDVWSC 204
Query: 945 GCIFYYVLSKGEHPFGDRILRE--ANILKGDYRLDGIKKSIQERSVCIEAADLIKSMLEQ 1002
G I Y +L G PF D + I G Y L S EA DLI ML
Sbjct: 205 GVILYALLC-GTLPFDDENIPNLFKKIKGGIYTLPSHLSS--------EARDLIPRMLIV 255
Query: 1003 NPLLRPASDEILKHPLF 1019
+P+ R EI +H F
Sbjct: 256 DPVKRITIPEIRQHRWF 272
>At2g46700 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-Hand protein
superfamily
Length = 595
Score = 65.9 bits (159), Expect = 4e-10
Identities = 75/300 (25%), Positives = 123/300 (41%), Gaps = 68/300 (22%)
Query: 726 QGKFQNRPVAVKRL-------LIDFYDIASKEIQLLSESDDHPNVIRYYFSESTEKFMYI 778
+G ++ P+AVK + I D+ +E++LL H +I+YY + +YI
Sbjct: 164 KGDIKDHPIAVKIISKAKMTTAIAIEDVR-REVKLLKSLSGHKYLIKYYDACEDANNVYI 222
Query: 779 AVELCSAS-LEDVIEGSKGLAKNVAVQKNIDPINVLFQITSGVNHLHSMKIVHRDLKPQN 837
+ELC L D I LA+ ++ D ++ QI + V+ H +VHRDLKP+N
Sbjct: 223 VMELCDGGELLDRI-----LARGGKYPED-DAKAIVVQILTVVSFCHLQGVVHRDLKPEN 276
Query: 838 ILIAPPKRYLSLHASKNKFRVLISDFGLCKKLEIDESSFRTNNFNNPTGTSGWRAPEIIS 897
L +S+ + + DFGL + DE N+ G++ + APE++
Sbjct: 277 FLFT---------SSREDSDLKLIDFGLSDFIRPDE------RLNDIVGSAYYVAPEVLH 321
Query: 898 GEVSLSESFAXXXXXXXXXXXXXXLDVNHMDLVTKKRLTRAVDIFSLGCIFYYVLSKGEH 957
SL DI+S+G I Y +L G
Sbjct: 322 RSYSLE-----------------------------------ADIWSIGVITYILLC-GSR 345
Query: 958 PFGDRILREANILKGDYRLDGIKKSIQERSVCIEAADLIKSMLEQNPLLRPASDEILKHP 1017
PF R E+ I + R + + S E D +K +L ++ R ++ + L HP
Sbjct: 346 PFWAR--TESGIFRTVLRTEPNYDDVPWPSCSSEGKDFVKRLLNKDYRKRMSAVQALTHP 403
>At2g17890 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-Hand protein
superfamily
Length = 571
Score = 65.9 bits (159), Expect = 4e-10
Identities = 85/343 (24%), Positives = 139/343 (39%), Gaps = 85/343 (24%)
Query: 691 GPMLDF---KEFEQEGHLKHLSISSRVLGYGSSG-TVVFQGKFQNRPVAVKRL------- 739
G +DF K+F+ H ++LG+G G T V K VAVK++
Sbjct: 93 GKRVDFGYAKDFD------HRYTIGKLLGHGQFGYTYVATDKKTGDRVAVKKIDKAKMTI 146
Query: 740 LIDFYDIASKEIQLLSESDDHPNVIRYYFSESTEKFMYIAVELC-SASLEDVIEGSKGLA 798
I D+ +E+++L H NV+R+Y + + +YI +ELC L D I LA
Sbjct: 147 PIAVEDV-KREVKILQALTGHENVVRFYNAFEDKNSVYIVMELCEGGELLDRI-----LA 200
Query: 799 KNVAVQKNIDPINVLFQITSGVNHLHSMKIVHRDLKPQNILIAPPKRYLSLHASKNKFRV 858
+ + D V+ Q+ H +VHRD+KP+N L + L A
Sbjct: 201 RKDSRYSERDAAVVVRQMLKVAAECHLRGLVHRDMKPENFLFKSTEEDSPLKA------- 253
Query: 859 LISDFGLCKKLEIDESSFRTNNFNNPTGTSGWRAPEIISGEVSLSESFAXXXXXXXXXXX 918
+DFGL ++ + F++ G++ + APE++
Sbjct: 254 --TDFGLSDFIKPGK------KFHDIVGSAYYVAPEVL---------------------- 283
Query: 919 XXXLDVNHMDLVTKKRLTRAVDIFSLGCIFYYVLSKGEHPFGDR----ILREANILKGDY 974
K+R D++S+G I Y +L G PF D+ I +E K D+
Sbjct: 284 -------------KRRSGPESDVWSIGVISYILLC-GRRPFWDKTEDGIFKEVLKNKPDF 329
Query: 975 RLDGIKKSIQERSVCIEAADLIKSMLEQNPLLRPASDEILKHP 1017
R ++ A D +K +L ++P R + + L HP
Sbjct: 330 RRK------PWPTISNSAKDFVKKLLVKDPRARLTAAQALSHP 366
>At1g66880 [T] KOG1187 Serine/threonine protein kinase
Length = 1286
Score = 65.9 bits (159), Expect = 4e-10
Identities = 52/188 (27%), Positives = 91/188 (47%), Gaps = 25/188 (13%)
Query: 712 SRVLGYGSSGTVVFQGKFQNRPVAVKRLL---IDFYDIASKEIQLLSESDDHPNVIRYY- 767
SR LG G GTV + R VAVKRL + + EI++L +S HPN++ Y
Sbjct: 960 SRELGDGGFGTVYYGVLKDGRAVAVKRLYERSLKRVEQFKNEIEIL-KSLKHPNLVILYG 1018
Query: 768 -FSESTEKFMYIAVELCSASLEDVIEGSKGLAKNVAVQKNIDPINVLFQITSGVNHLHSM 826
S + + + + + + +L + + G++ A+ + + N+ + S ++ LH
Sbjct: 1019 CTSRHSRELLLVYEYISNGTLAEHLHGNRAEARPLCWSTRL---NIAIETASALSFLHIK 1075
Query: 827 KIVHRDLKPQNILIAPPKRYLSLHASKNKFRVLISDFGLCKKLEIDESSFRTNNFNNPTG 886
I+HRD+K NIL+ + ++V ++DFGL + +D++ T P G
Sbjct: 1076 GIIHRDIKTTNILL------------DDNYQVKVADFGLSRLFPMDQTHIST----APQG 1119
Query: 887 TSGWRAPE 894
T G+ PE
Sbjct: 1120 TPGYVDPE 1127
>Hs5453882 [G] KOG0599 Phosphorylase kinase gamma subunit
Length = 387
Score = 65.5 bits (158), Expect = 5e-10
Identities = 68/273 (24%), Positives = 110/273 (39%), Gaps = 59/273 (21%)
Query: 749 KEIQLLSESDDHPNVIRYYFSESTEKFMYIAVELCSASLEDVIEGSKGLAKNVAVQKNID 808
KE+ +L + HPN+I+ + T F ++ +L E L + V + + +
Sbjct: 73 KEVDILRKVSGHPNIIQLKDTYETNTFFFLVFDLMKRG-----ELFDYLTEKVTLSEK-E 126
Query: 809 PINVLFQITSGVNHLHSMKIVHRDLKPQNILIAPPKRYLSLHASKNKFRVLISDFGLCKK 868
++ + + LH + IVHRDLKP+NIL+ + + ++DFG +
Sbjct: 127 TRKIMRALLEVICTLHKLNIVHRDLKPENILL------------DDNMNIKLTDFGFSCQ 174
Query: 869 LEIDESSFRTNNFNNPTGTSGWRAPEIISGEVSLSESFAXXXXXXXXXXXXXXLDVNHMD 928
LE E GT + APEII E S++E
Sbjct: 175 LEPGE------RLREVCGTPSYLAPEII--ECSMNEDHPGYG------------------ 208
Query: 929 LVTKKRLTRAVDIFSLGCIFYYVLSKGEHPFGDR--ILREANILKGDYRLDGIKKSIQER 986
+ VD++S G I Y +L+ G PF R +L I+ G+Y+ +
Sbjct: 209 --------KEVDMWSTGVIMYTLLA-GSPPFWHRKQMLMLRMIMSGNYQFGSPEWDDYSD 259
Query: 987 SVCIEAADLIKSMLEQNPLLRPASDEILKHPLF 1019
+V DL+ L P R ++E L HP F
Sbjct: 260 TV----KDLVSRFLVVQPQNRYTAEEALAHPFF 288
>CE28273 [T] KOG0587 Traf2- and Nck-interacting kinase and related germinal
center kinase (GCK) family protein kinases
Length = 1096
Score = 65.5 bits (158), Expect = 5e-10
Identities = 57/201 (28%), Positives = 94/201 (46%), Gaps = 36/201 (17%)
Query: 714 VLGYGSSGTVVFQGKF----QNRPVAVKRLLIDFYDIASKEIQLLSESDDHPNVIRYY-- 767
V+G G+ G V ++G+ Q + + + D D EI +L + H NV YY
Sbjct: 26 VVGNGTYGQV-YKGRHVKTAQLAAIKIMNINEDEEDEIKLEINMLKKHSHHRNVATYYGA 84
Query: 768 ----FSESTEKF--MYIAVELC-SASLEDVIEGSKGLAKNVAVQKNIDPINVLFQITSGV 820
ST K +++ +E C S S+ D+++ +KG K + +I G+
Sbjct: 85 FIKKLPSSTGKHDQLWLVMEFCGSGSITDLVKNTKG-----GSLKEEWIAYICREILRGL 139
Query: 821 NHLHSMKIVHRDLKPQNILIAPPKRYLSLHASKNKFRVLISDFGLCKKLEIDESSFRTNN 880
HLH K++HRD+K QN+L+ + V + DFG+ ++D++ R N
Sbjct: 140 YHLHQSKVIHRDIKGQNVLLT------------DSAEVKLVDFGV--SAQLDKTVGRRNT 185
Query: 881 FNNPTGTSGWRAPEIISGEVS 901
F GT W APE+I+ + S
Sbjct: 186 F---IGTPYWMAPEVIACDES 203
>CE25673 [T] KOG0587 Traf2- and Nck-interacting kinase and related germinal
center kinase (GCK) family protein kinases
Length = 1082
Score = 65.5 bits (158), Expect = 5e-10
Identities = 57/201 (28%), Positives = 94/201 (46%), Gaps = 36/201 (17%)
Query: 714 VLGYGSSGTVVFQGKF----QNRPVAVKRLLIDFYDIASKEIQLLSESDDHPNVIRYY-- 767
V+G G+ G V ++G+ Q + + + D D EI +L + H NV YY
Sbjct: 26 VVGNGTYGQV-YKGRHVKTAQLAAIKIMNINEDEEDEIKLEINMLKKHSHHRNVATYYGA 84
Query: 768 ----FSESTEKF--MYIAVELC-SASLEDVIEGSKGLAKNVAVQKNIDPINVLFQITSGV 820
ST K +++ +E C S S+ D+++ +KG K + +I G+
Sbjct: 85 FIKKLPSSTGKHDQLWLVMEFCGSGSITDLVKNTKG-----GSLKEEWIAYICREILRGL 139
Query: 821 NHLHSMKIVHRDLKPQNILIAPPKRYLSLHASKNKFRVLISDFGLCKKLEIDESSFRTNN 880
HLH K++HRD+K QN+L+ + V + DFG+ ++D++ R N
Sbjct: 140 YHLHQSKVIHRDIKGQNVLLT------------DSAEVKLVDFGV--SAQLDKTVGRRNT 185
Query: 881 FNNPTGTSGWRAPEIISGEVS 901
F GT W APE+I+ + S
Sbjct: 186 F---IGTPYWMAPEVIACDES 203
>CE25672 [T] KOG0587 Traf2- and Nck-interacting kinase and related germinal
center kinase (GCK) family protein kinases
Length = 1087
Score = 65.5 bits (158), Expect = 5e-10
Identities = 57/201 (28%), Positives = 94/201 (46%), Gaps = 36/201 (17%)
Query: 714 VLGYGSSGTVVFQGKF----QNRPVAVKRLLIDFYDIASKEIQLLSESDDHPNVIRYY-- 767
V+G G+ G V ++G+ Q + + + D D EI +L + H NV YY
Sbjct: 26 VVGNGTYGQV-YKGRHVKTAQLAAIKIMNINEDEEDEIKLEINMLKKHSHHRNVATYYGA 84
Query: 768 ----FSESTEKF--MYIAVELC-SASLEDVIEGSKGLAKNVAVQKNIDPINVLFQITSGV 820
ST K +++ +E C S S+ D+++ +KG K + +I G+
Sbjct: 85 FIKKLPSSTGKHDQLWLVMEFCGSGSITDLVKNTKG-----GSLKEEWIAYICREILRGL 139
Query: 821 NHLHSMKIVHRDLKPQNILIAPPKRYLSLHASKNKFRVLISDFGLCKKLEIDESSFRTNN 880
HLH K++HRD+K QN+L+ + V + DFG+ ++D++ R N
Sbjct: 140 YHLHQSKVIHRDIKGQNVLLT------------DSAEVKLVDFGV--SAQLDKTVGRRNT 185
Query: 881 FNNPTGTSGWRAPEIISGEVS 901
F GT W APE+I+ + S
Sbjct: 186 F---IGTPYWMAPEVIACDES 203
>CE18967 [T] KOG4236 Serine/threonine protein kinase PKC mu/PKD and related
proteins
Length = 1101
Score = 65.5 bits (158), Expect = 5e-10
Identities = 73/260 (28%), Positives = 111/260 (42%), Gaps = 68/260 (26%)
Query: 711 SSRVLGYGSSGTVVFQGKFQN-RPVAVKRLLIDFY-------DIASKEIQLLSESDDHPN 762
+ VLG G GTV +N + VAVK LID D+ E+Q+L E DHP
Sbjct: 772 AEEVLGSGQFGTVYGGIHRRNGQHVAVK--LIDKLKFPPNKEDLLRAEVQIL-EKVDHPG 828
Query: 763 VIRYY-FSESTEKFMYIAVELCSASLEDVIEGSKGLAKNVAVQKNIDPINVLFQITSGVN 821
V+ + E+T++ + +L LE ++ KG Q ++ QI +
Sbjct: 829 VVHFMQMLETTDRIFVVMEKLKGDMLEMILSSEKGRLSERTTQF------LVAQILEALR 882
Query: 822 HLHSMKIVHRDLKPQNILIAPPKRYLSLHASKNKFRVLISDFGLCKKLEIDESSFRTNNF 881
+LH + IVH DLKP+NIL L+++ + +V + DFG + I E SFR
Sbjct: 883 YLHHLNIVHCDLKPENIL---------LNSNSDFPQVKLCDFGFAR--IIGEKSFR---- 927
Query: 882 NNPTGTSGWRAPEIISGEVSLSESFAXXXXXXXXXXXXXXLDVNHMDLVTKKRLTRAVDI 941
+ GT + APE++ K R++D+
Sbjct: 928 RSVVGTPAYLAPEVL----------------------------------RNKGFNRSLDM 953
Query: 942 FSLGCIFYYVLSKGEHPFGD 961
+S+G I Y LS G PF +
Sbjct: 954 WSVGVIVYVSLS-GTFPFNE 972
>At4g00720 [G] KOG0658 Glycogen synthase kinase-3
Length = 472
Score = 65.5 bits (158), Expect = 5e-10
Identities = 88/338 (26%), Positives = 136/338 (40%), Gaps = 82/338 (24%)
Query: 710 ISSRVLGYGSSGTVVFQGKF--QNRPVAVKRLLIDFYDIASKEIQLLSESDDHPNVIRY- 766
++ RV+G GS G VVFQ K VA+K++L D ++E+Q++ DHPNV+R
Sbjct: 139 MAQRVVGTGSFG-VVFQAKCLETGEQVAIKKVLQD-KRYKNRELQIM-RLQDHPNVVRLR 195
Query: 767 --YFSESTEKFMYIAVELCSASLEDVIEGSKGLAKNVAVQKNIDPINVLFQITSGVNHLH 824
+FS + + +Y+ + L E V SK K I +QI +N+LH
Sbjct: 196 HSFFSTTDKDELYLNLVLEYVP-ETVYRASKHYTKMNQHMPIIFVQLYTYQICRALNYLH 254
Query: 825 SMK-IVHRDLKPQNILIAPPKRYLSLHASKNKFRVLISDFGLCKKLEIDESSFRTNNFNN 883
+ + HRD+KPQN+L+ P L I DFG K L E + +
Sbjct: 255 RVVGVCHRDIKPQNLLVNPQTHQLK-----------ICDFGSAKMLVPGEPNI------S 297
Query: 884 PTGTSGWRAPEIISGEVSLSESFAXXXXXXXXXXXXXXLDVNHMDLVTKKRLTRAVDIFS 943
+ +RAPE+I G T A+D++S
Sbjct: 298 YICSRYYRAPELIFGAT---------------------------------EYTNAIDMWS 324
Query: 944 LGCIFYYV-----LSKGEHPFGDRI-------------LREANILKGDYRLDGIK----K 981
GC+ + L GE + +R N +++ IK
Sbjct: 325 GGCVMAELLLGQPLFPGESGIDQLVEIIKILGTPTREEIRCMNPNYTEFKFPQIKAHPWH 384
Query: 982 SIQERSVCIEAADLIKSMLEQNPLLRPASDEILKHPLF 1019
I + + EA DL+ +L+ +P LR + E HP F
Sbjct: 385 KIFHKRMPPEAVDLVSRLLQYSPNLRCTALEACAHPFF 422
>At2g41140 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-Hand protein
superfamily
Length = 576
Score = 65.5 bits (158), Expect = 5e-10
Identities = 73/305 (23%), Positives = 128/305 (41%), Gaps = 70/305 (22%)
Query: 726 QGKFQNRPVAVKRL-------LIDFYDIASKEIQLLSESDDHPNVIRYYFSESTEKFMYI 778
+G + + VAVK + I D+ S+E+++L H N++++Y + ++ +YI
Sbjct: 144 KGSLKGQEVAVKVIPKSKMTTAIAIEDV-SREVKMLRALTGHKNLVQFYDAFEDDENVYI 202
Query: 779 AVELCSAS--LEDVIEGSKGLAKNVAVQKNIDPINVLFQITSGVNHLHSMKIVHRDLKPQ 836
+ELC L+ +++ +++ D V+ QI S V + H +VHRDLKP+
Sbjct: 203 VMELCKGGELLDKILQRGGKYSED-------DAKKVMVQILSVVAYCHLQGVVHRDLKPE 255
Query: 837 NILIAPPKRYLSLHASKNKFRVLISDFGLCKKLEIDESSFRTNNFNNPTGTSGWRAPEII 896
N L + L A DFGL ++ DE N+ G++ + APE++
Sbjct: 256 NFLFSTKDETSPLKA---------IDFGLSDYVKPDE------RLNDIVGSAYYVAPEVL 300
Query: 897 SGEVSLSESFAXXXXXXXXXXXXXXLDVNHMDLVTKKRLTRAVDIFSLGCIFYYVLSKGE 956
H T+ D++S+G I Y +L G
Sbjct: 301 -----------------------------HRTYGTE------ADMWSIGVIAYILLC-GS 324
Query: 957 HPFGDRILREANILKGDYRLDGIKKSIQERSVCIEAADLIKSMLEQNPLLRPASDEILKH 1016
PF R E+ I + + + + S+ EA D +K +L ++ R + + L H
Sbjct: 325 RPFWAR--TESGIFRAVLKAEPNFEEAPWPSLSPEAVDFVKRLLNKDYRKRLTAAQALCH 382
Query: 1017 PLFWG 1021
P G
Sbjct: 383 PWLVG 387
>At1g63700 [T] KOG0198 MEKK and related serine/threonine protein kinases
Length = 883
Score = 65.5 bits (158), Expect = 5e-10
Identities = 84/317 (26%), Positives = 135/317 (42%), Gaps = 80/317 (25%)
Query: 713 RVLGYGSSGTVVFQGKFQNRPV-AVKRLLIDFYDIASKE--------IQLLSESDDHPNV 763
R+LG GS G V ++ + A+K + + D S+E I +LS H N+
Sbjct: 404 RLLGMGSFGHVYLGFNSESGEMCAMKEVTLCSDDPKSRESAQQLGQEISVLSRLR-HQNI 462
Query: 764 IRYYFSESTEKFMYIAVELCSA-SLEDVIEGSKGLAKNVAVQKNIDPINVLFQITSGVNH 822
++YY SE+ + +YI +E S S+ +++ +N A++ N QI SG+ +
Sbjct: 463 VQYYGSETVDDKLYIYLEYVSGGSIYKLLQEYGQFGEN-AIR------NYTQQILSGLAY 515
Query: 823 LHSMKIVHRDLKPQNILIAPPKRYLSLHASKNKFRVLISDFGLCKKLEIDES--SFRTNN 880
LH+ VHRD+K NIL+ P H RV ++DFG+ K + SF+
Sbjct: 516 LHAKNTVHRDIKGANILVDP-------HG-----RVKVADFGMAKHITAQSGPLSFK--- 560
Query: 881 FNNPTGTSGWRAPEIISGEVSLSESFAXXXXXXXXXXXXXXLDVNHMDLVTKKRLTRAVD 940
G+ W APE+I N +L AVD
Sbjct: 561 -----GSPYWMAPEVIKNS-------------------------NGSNL--------AVD 582
Query: 941 IFSLGCIFYYVLSKGEHPFGDRILREANILKGDYR-LDGIKKSIQERSVCIEAADLIKSM 999
I+SLGC ++ + P+ A G+ + L I + E E D ++
Sbjct: 583 IWSLGCT-VLEMATTKPPWSQYEGVPAMFKIGNSKELPDIPDHLSE-----EGKDFVRKC 636
Query: 1000 LEQNPLLRPASDEILKH 1016
L++NP RP + ++L H
Sbjct: 637 LQRNPANRPTAAQLLDH 653
>SPBC11B10.09 [R] KOG0594 Protein kinase PCTAIRE and related kinases
Length = 297
Score = 65.1 bits (157), Expect = 6e-10
Identities = 68/282 (24%), Positives = 112/282 (39%), Gaps = 79/282 (28%)
Query: 715 LGYGSSGTVV-FQGKFQNRPVAVKRLLID-----FYDIASKEIQLLSESDDH---PNVIR 765
+G G+ G V + K R VA+K++ ++ A +EI LL E +D N +R
Sbjct: 10 IGEGTYGVVYKARHKLSGRIVAMKKIRLEDESEGVPSTAIREISLLKEVNDENNRSNCVR 69
Query: 766 YYFSESTEKFMYIAVELCSASLEDVIEGSKGLAKNVAVQKNIDPINV---LFQITSGVNH 822
E +Y+ E L+ ++ ++DP V +Q+ +GVN
Sbjct: 70 LLDILHAESKLYLVFEFLDMDLKKYMDRISETGAT-----SLDPRLVQKFTYQLVNGVNF 124
Query: 823 LHSMKIVHRDLKPQNILIAPPKRYLSLHASKNKFRVLISDFGLCKKLEIDESSFRTNNFN 882
HS +I+HRDLKPQN+LI + + ++DFGL + + N+
Sbjct: 125 CHSRRIIHRDLKPQNLLI------------DKEGNLKLADFGLARSFGVP-----LRNYT 167
Query: 883 NPTGTSGWRAPEIISGEVSLSESFAXXXXXXXXXXXXXXLDVNHMDLVTKKRLTRAVDIF 942
+ T +RAPE++ G + + VDI+
Sbjct: 168 HEIVTLWYRAPEVLLG---------------------------------SRHYSTGVDIW 194
Query: 943 SLGCIFYYVLSKGEHPFGDRILREANILKGDYRLDGIKKSIQ 984
S+GCIF ++R + + GD +D I K Q
Sbjct: 195 SVGCIF------------AEMIRRSPLFPGDSEIDEIFKIFQ 224
>Hs7662210 [OUT] KOG0595 Serine/threonine-protein kinase involved in autophagy
Length = 1036
Score = 65.1 bits (157), Expect = 6e-10
Identities = 57/195 (29%), Positives = 97/195 (49%), Gaps = 28/195 (14%)
Query: 714 VLGYGSSGTVVFQGKFQNRP---VAVKRL----LIDFYDIASKEIQLLSESDDHPNVIRY 766
++G+G+ VVF+G+ + + VA+K + L + KEI++L E H N++
Sbjct: 14 LVGHGAFA-VVFRGRHRQKTDWEVAIKSINKKNLSKSQILLGKEIKILKELQ-HENIVAL 71
Query: 767 YFSESTEKFMYIAVELCSAS-LEDVIEGSKGLAKNVAVQKNIDPINV-LFQITSGVNHLH 824
Y + +++ +E C+ L D ++ L++ D I V L QI + + LH
Sbjct: 72 YDVQELPNSVFLVMEYCNGGDLADYLQAKGTLSE--------DTIRVFLHQIAAAMRILH 123
Query: 825 SMKIVHRDLKPQNILIAPPKRYLSLHASKNKFRVLISDFGLCKKLEIDESSFRTNNFNNP 884
S I+HRDLKPQNIL++ R S S + R+ I+DFG + L + +
Sbjct: 124 SKGIIHRDLKPQNILLSYANRRKS---SVSGIRIKIADFGFARYLHSNMMAATL------ 174
Query: 885 TGTSGWRAPEIISGE 899
G+ + APE+I +
Sbjct: 175 CGSPMYMAPEVIMSQ 189
>CE25046 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-Hand protein
superfamily
Length = 348
Score = 65.1 bits (157), Expect = 6e-10
Identities = 66/265 (24%), Positives = 110/265 (40%), Gaps = 65/265 (24%)
Query: 760 HPNVIRYYFSESTEKFMYIAVELCSAS-LEDVIEGSKGLAKNVAVQKNIDPINVLFQITS 818
H N+++ + + ++F+Y+ +EL + L D I +AK ++ D N++ Q+
Sbjct: 78 HNNIVQLFDTYDEKQFVYLVMELVTGGELFDRI-----VAKGSYTEQ--DASNLIRQVLE 130
Query: 819 GVNHLHSMKIVHRDLKPQNILIAPPKRYLSLHASKNKFRVLISDFGLCKKLEIDESSFRT 878
V +H +VHRDLKP+N+L + +++ISDFGL K + +
Sbjct: 131 AVGFMHDNGVVHRDLKPENLL---------YYNQDEDSKIMISDFGLSKTED-------S 174
Query: 879 NNFNNPTGTSGWRAPEIISGEVSLSESFAXXXXXXXXXXXXXXLDVNHMDLVTKKRLTRA 938
GT G+ APE++ +K +A
Sbjct: 175 GVMATACGTPGYVAPEVLQ----------------------------------QKPYGKA 200
Query: 939 VDIFSLGCIFYYVLSKGEHPFGDRILRE--ANILKGDYRLDGIKKSIQERSVCIEAADLI 996
VD++S+G I Y +L G PF D A I+KG+Y D + + A D I
Sbjct: 201 VDVWSIGVIAYILLC-GYPPFYDESDANLFAQIIKGEYEFD----APYWDQISDSAKDFI 255
Query: 997 KSMLEQNPLLRPASDEILKHPLFWG 1021
++ +P R + L HP G
Sbjct: 256 THLMCCDPEARFTCQDALSHPWISG 280
>CE17815 [K] KOG0666 Cyclin C-dependent kinase CDK8
Length = 622
Score = 65.1 bits (157), Expect = 6e-10
Identities = 71/260 (27%), Positives = 119/260 (45%), Gaps = 66/260 (25%)
Query: 711 SSRVLGYGSSGTVVF------QGKFQNRPVAVKRLLIDFYDI-ASKEIQLLSESDDHPNV 763
+S+ +G G+ G V G+F N+ A+K + + + A +EI L E HPN+
Sbjct: 28 NSKEIGRGTYGLVYKAVPKKQNGQFPNKEYALKMIEGQGFSMSACREIALFRELR-HPNL 86
Query: 764 I---RYYFSESTEKFMYIAVELCSASLEDVIEG---SKGLAKNVAVQKNIDPINVLFQIT 817
I R + + EK +++ ++ L VI+ +K + V +N+ N+LFQI
Sbjct: 87 ICLQRVFLTN--EKKVWLLLDYAEHDLWHVIKHHRTAKSKKVPIMVPRNMVK-NILFQIL 143
Query: 818 SGVNHLHSMKIVHRDLKPQNILI---APPKRYLSLHASKNKFRVLISDFGLCKKLEIDES 874
SG+++LHS ++HRDLKP NIL+ PP + RV I+D G + I +
Sbjct: 144 SGMHYLHSNWVLHRDLKPANILLMGDGPPDM---------RGRVKIADLGFSR---IYAN 191
Query: 875 SFRTNNFNNPTGTSGW-RAPEIISGEVSLSESFAXXXXXXXXXXXXXXLDVNHMDLVTKK 933
+ +P + W RAPE++ G K
Sbjct: 192 PLKPMAELDPVVVTFWYRAPELLLG---------------------------------AK 218
Query: 934 RLTRAVDIFSLGCIFYYVLS 953
T+A+D++++GCIF +L+
Sbjct: 219 HYTKAIDVWAIGCIFAELLT 238
>At5g23580 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-Hand protein
superfamily
Length = 490
Score = 65.1 bits (157), Expect = 6e-10
Identities = 85/325 (26%), Positives = 129/325 (39%), Gaps = 76/325 (23%)
Query: 713 RVLGYGSSGTVVF------QGKFQNRPVAVKRLLI-DFYDIASKEIQLLSESDDHPNVIR 765
+VLG G GT K + + ++LL + YD +EIQ++ ++PNV+R
Sbjct: 26 QVLGQGQFGTTFLCTHKQTGQKLACKSIPKRKLLCQEDYDDVLREIQIMHHLSEYPNVVR 85
Query: 766 YYFSESTEKFMYIAVELC-SASLEDVIEGSKGLAKNVAVQKNIDPINVLFQITSGVNHLH 824
+ K +++ +ELC L D I ++ A + ++ I V H
Sbjct: 86 IESAYEDTKNVHLVMELCEGGELFDRIVKRGHYSEREAAK-------LIKTIVGVVEACH 138
Query: 825 SMKIVHRDLKPQNILIAPPKRYLSLHASKNKFRVLISDFGLCKKLEIDESSFRTNNFNNP 884
S+ +VHRDLKP+N L + SL + +DFGL E+ F+
Sbjct: 139 SLGVVHRDLKPENFLFSSSDEDASLKS---------TDFGLSVFCTPGEA------FSEL 183
Query: 885 TGTSGWRAPEIISGEVSLSESFAXXXXXXXXXXXXXXLDVNHMDLVTKKRLTRAVDIFSL 944
G++ + APE++ K D++S
Sbjct: 184 VGSAYYVAPEVL-----------------------------------HKHYGPECDVWSA 208
Query: 945 GCIFYYVLSKGEHPF--GDRILREANILKGDYRLD-GIKKSIQERSVCIEAADLIKSMLE 1001
G I Y +L G PF I IL+G + SI E A DLIK MLE
Sbjct: 209 GVILYILLC-GFPPFWAESEIGIFRKILQGKLEFEINPWPSISE-----SAKDLIKKMLE 262
Query: 1002 QNPLLRPASDEILKHPLFWGVSKKL 1026
NP R + ++L HP W V K+
Sbjct: 263 SNPKKRLTAHQVLCHP--WIVDDKV 285
>At3g10540 [T] KOG0592 3-phosphoinositide-dependent protein kinase (PDK1)
Length = 483
Score = 65.1 bits (157), Expect = 6e-10
Identities = 83/343 (24%), Positives = 147/343 (42%), Gaps = 79/343 (23%)
Query: 701 QEGHLKHLSISSRVLGYGSSGTVVFQGKFQNRPV-AVKRLLIDFYDIASKEI-----QLL 754
QE H ++ G GS VV K N V A+K + F +K +++
Sbjct: 34 QENFTYHDFELGKIYGVGSYSKVVRAKKKDNGTVYALKIMDKKFITKENKTAYVKLERIV 93
Query: 755 SESDDHPNVIRYYFSESTEKFMYIAVELCSAS-LEDVIEGSKGLAKNVAVQKNIDPINVL 813
+ +HP +++ +F+ + +Y+A+E C L D I L+++ A + + ++ L
Sbjct: 94 LDQLEHPGIVKLFFTFQDTQSLYMALESCEGGELFDQITRKGRLSEDEARFYSAEVVDAL 153
Query: 814 FQITSGVNHLHSMKIVHRDLKPQNILIAPPKRYLSLHASKNKFRVLISDFGLCKKLEIDE 873
++H+M ++HRD+KP+N+L+ L H + I+DFG K ++ +
Sbjct: 154 -------EYIHNMGLIHRDIKPENLLLT-----LDGH-------IKIADFGSVKPMQDSQ 194
Query: 874 SSFRTNNFNNP-----TGTSGWRAPEIISGEVSLSESFAXXXXXXXXXXXXXXLDVNHMD 928
+ N ++ GT+ + PE+++ +
Sbjct: 195 ITVLPNAASDDKACTFVGTAAYVPPEVLNSSPA--------------------------- 227
Query: 929 LVTKKRLTRAVDIFSLGCIFYYVLSKGEHPFGDRILREANILKGDYRLDGIKKSIQERSV 988
T D+++LGC Y +LS G PF D E I + R+ I + I+ +
Sbjct: 228 -------TFGNDLWALGCTLYQMLS-GTSPFKD--ASEWLIFQ---RI--IARDIKFPNH 272
Query: 989 CIEAA-DLIKSMLEQNPLLRPAS-----DEILKHPLFWGVSKK 1025
EAA DLI +L+ +P RP + D + +HP F GV K
Sbjct: 273 FSEAARDLIDRLLDTDPSRRPGAGSEGYDSLKRHPFFKGVDWK 315
>At3g08730 [RT] KOG0598 Ribosomal protein S6 kinase and related proteins
Length = 465
Score = 65.1 bits (157), Expect = 6e-10
Identities = 78/328 (23%), Positives = 139/328 (41%), Gaps = 80/328 (24%)
Query: 713 RVLGYGSSGTVVFQGKFQNRPVAVKRLLIDFYDIASKEIQLL-SESD-----DHPNVIRY 766
+V+G G+ G V K + + +++ + + + + +E D DHP +++
Sbjct: 138 KVVGKGAFGKVYQVRKKETSEIYAMKVMRKDHIMEKNHAEYMKAERDILTKIDHPFIVQL 197
Query: 767 YFSESTEKFMYIAVELCSASLEDVIEGSKGLAKNVAVQKNIDPINVLFQITSGVNHLHSM 826
+S T+ +Y+ ++ + +GL + + +I S V+HLH
Sbjct: 198 KYSFQTKYRLYLVLDFINGGHLFFQLYHQGLFREDLARV------YTAEIVSAVSHLHEK 251
Query: 827 KIVHRDLKPQNILIAPPKRYLSLHASKNKFRVLISDFGLCKKLEIDESSFRTNNFNNPTG 886
I+HRDLKP+NIL+ V+++DFGL K+ E + S N+ G
Sbjct: 252 GIMHRDLKPENILM------------DTDGHVMLTDFGLAKEFEENTRS------NSMCG 293
Query: 887 TSGWRAPEIISGEVSLSESFAXXXXXXXXXXXXXXLDVNHMDLVTKKRLTRAVDIFSLGC 946
T+ + APEI+ G K +A D +S+G
Sbjct: 294 TTEYMAPEIVRG----------------------------------KGHDKAADWWSVGI 319
Query: 947 IFYYVLSKGEHPF-GDRILREANILKGDYRLDGIKKSIQERSVCIEAADLIKSMLEQNPL 1005
+ Y +L+ G+ PF G + + I+K +L + EA ++K +L++ P
Sbjct: 320 LLYEMLT-GKPPFLGSKGKIQQKIVKDKIKLPQFLSN--------EAHAILKGLLQKEPE 370
Query: 1006 LRPAS-----DEILKHPLFWGVS-KKLE 1027
R S +EI +H F G++ KKLE
Sbjct: 371 RRLGSGLSGAEEIKQHKWFKGINWKKLE 398
>7304311 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 405
Score = 65.1 bits (157), Expect = 6e-10
Identities = 58/224 (25%), Positives = 98/224 (42%), Gaps = 67/224 (29%)
Query: 760 HPNVIRYYFSESTEKFMYIAVELCSAS--LEDVIEGSKGLAKNVAVQKNIDPINVLFQIT 817
HPN+++ + + +Y+ +EL + + ++E K D +++ QI
Sbjct: 102 HPNIVQLLETYEDKSKVYLVMELVTGGELFDRIVEKGSYTEK--------DASHLIRQIL 153
Query: 818 SGVNHLHSMKIVHRDLKPQNILIAPPKRYLSLHASKNKFRVLISDFGLCKKLEIDESSFR 877
V+++H +VHRDLKP+N+L P + +++ISDFGL K +++S
Sbjct: 154 EAVDYMHEQGVVHRDLKPENLLYYSP---------DDDSKIMISDFGLSK---MEDSGIM 201
Query: 878 TNNFNNPTGTSGWRAPEIISGEVSLSESFAXXXXXXXXXXXXXXLDVNHMDLVTKKRLTR 937
GT G+ APE+++ +K +
Sbjct: 202 A----TACGTPGYVAPEVLA----------------------------------QKPYGK 223
Query: 938 AVDIFSLGCIFYYVLSKGEHPFGDRILREAN----ILKGDYRLD 977
AVD++S+G I Y +L G PF D +AN ILKGD+ D
Sbjct: 224 AVDVWSIGVISYILLC-GYPPFYDE--NDANLFAQILKGDFEFD 264
>SPAC644.06c [D] KOG0588 Serine/threonine protein kinase
Length = 593
Score = 64.3 bits (155), Expect = 1e-09
Identities = 89/352 (25%), Positives = 137/352 (38%), Gaps = 85/352 (24%)
Query: 713 RVLGYGSSGTVVFQGKFQNRPVAVKRLLIDFYDIASKEIQLLSESDDHPNVIRYYFSEST 772
+ LG GS+ V + +A +++ Y EI L+ HPN++R Y +
Sbjct: 16 KTLGTGSTSCVRLAKHAKTGDLAAIKIIPIRYASIGMEI-LMMRLLRHPNILRLYDVWTD 74
Query: 773 EKFMYIAVELC-SASLEDVIEGSKGLAKNVAVQKNIDPINVLFQITSGVNHLHSMKIVHR 831
+ MY+A+E L I L++ A + L QI V H H + HR
Sbjct: 75 HQHMYLALEYVPDGELFHYIRKHGPLSEREAA-------HYLSQILDAVAHCHRFRFRHR 127
Query: 832 DLKPQNILIAPPKRYLSLHASKNKFRVLISDFGLCKKLEIDESSFRTNNFNNPTGTSGWR 891
DLK +NILI N+ ++ I+DFG+ +E ++S N G+ +
Sbjct: 128 DLKLENILI-----------KVNEQQIKIADFGMA-TVEPNDSC-----LENYCGSLHYL 170
Query: 892 APEIISGEVSLSESFAXXXXXXXXXXXXXXLDVNHMDLVTKKRLTRAVDIFSLGCIFYYV 951
APEI+S K D++S G I Y +
Sbjct: 171 APEIVS---------------------------------HKPYRGAPADVWSCGVILYSL 197
Query: 952 LSKGEHPFG----DRILREANILKGDYRLDGIKKSIQERSVCIEAADLIKSMLEQNPLLR 1007
LS + PFG D I + I G Y L S+ A DL+ ML+ NP R
Sbjct: 198 LS-NKLPFGGQNTDVIYNK--IRHGAYDLPS--------SISSAAQDLLHRMLDVNPSTR 246
Query: 1008 PASDEILKHPLFWGVSKKLEFLLKVSDRFEVERRDPPSPLLLKLEEVSAKVI 1059
E+ HP FL+ + ++ PP+P L ++E+ V+
Sbjct: 247 ITIPEVFSHP----------FLMGCTSLSSMDSTTPPTP-SLSIDEIDPLVV 287
>Hs7019543 [T] KOG0582 Ste20-like serine/threonine protein kinase
Length = 547
Score = 64.3 bits (155), Expect = 1e-09
Identities = 57/189 (30%), Positives = 91/189 (47%), Gaps = 24/189 (12%)
Query: 718 GSSGTVVFQG---KFQNRPVAVKRLLID----FYDIASKEIQLLSESDDHPNVIRYYFSE 770
GS T V Q K + VA+KR+ ++ D KEIQ +S+ HPNV+ YY S
Sbjct: 72 GSGATAVVQAALCKPRQERVAIKRINLEKCQTSMDELLKEIQAMSQCS-HPNVVTYYTSF 130
Query: 771 STEKFMYIAVELCSA-SLEDVIEG--SKGLAKNVAVQKNIDPINVLFQITSGVNHLHSMK 827
+ +++ ++L S S+ D+I+ ++G KN +++ I +L ++ G+++LH
Sbjct: 131 VVKDELWLVMKLLSGGSMLDIIKYIVNRGEHKNGVLEEAIIA-TILKEVLEGLDYLHRNG 189
Query: 828 IVHRDLKPQNILIAPPKRYLSLHASKNKFRVLISDFGLCKKLEIDESSFRTNNFNNPTGT 887
+HRDLK NIL+ V I+DFG+ L R GT
Sbjct: 190 QIHRDLKAGNILLG------------EDGSVQIADFGVSAFLATGGDVTRNKVRKTFVGT 237
Query: 888 SGWRAPEII 896
W APE++
Sbjct: 238 PCWMAPEVM 246
>Hs6031180 [T] KOG4645 MAPKKK (MAP kinase kinase kinase) SSK2 and related
serine/threonine protein kinases
Length = 1558
Score = 64.3 bits (155), Expect = 1e-09
Identities = 65/266 (24%), Positives = 110/266 (40%), Gaps = 67/266 (25%)
Query: 756 ESDDHPNVIRYYFSESTEKFMYIAVELCSASLEDVIEGSKGLAKNVAVQKNIDPINVLFQ 815
E HPN++RY+ E + MYI +E C EG+ + +Q+++ + Q
Sbjct: 1345 EGIKHPNLVRYFGVELHREEMYIFMEYCD-------EGTLEEVSRLGLQEHVIRLYSK-Q 1396
Query: 816 ITSGVNHLHSMKIVHRDLKPQNILIAPPKRYLSLHASKNKFRVLISDFGLCKKLEIDESS 875
IT +N LH IVHRD+K NI + + + + DFG KL+ + +
Sbjct: 1397 ITIAINVLHEHGIVHRDIKGANIFLT------------SSGLIKLGDFGCSVKLK-NNAQ 1443
Query: 876 FRTNNFNNPTGTSGWRAPEIISGEVSLSESFAXXXXXXXXXXXXXXLDVNHMDLVTKKRL 935
N+ GT+ + APE+I+
Sbjct: 1444 TMPGEVNSTLGTAAYMAPEVITRAKGEGHG------------------------------ 1473
Query: 936 TRAVDIFSLGCIFYYVLSKGEHPFGD-----RILREANILKGDYRLDGIKKSIQERSVCI 990
RA DI+SLGC+ +++ G+ P+ + +I+ + + G K I ER +
Sbjct: 1474 -RAADIWSLGCVVIEMVT-GKRPWHEYEHNFQIMYKVGM--------GHKPPIPER-LSP 1522
Query: 991 EAADLIKSMLEQNPLLRPASDEILKH 1016
E D + LE +P +R + ++L H
Sbjct: 1523 EGKDFLSHCLESDPKMRWTASQLLDH 1548
>Hs5803088 [T] KOG4645 MAPKKK (MAP kinase kinase kinase) SSK2 and related
serine/threonine protein kinases
Length = 1607
Score = 64.3 bits (155), Expect = 1e-09
Identities = 65/266 (24%), Positives = 110/266 (40%), Gaps = 67/266 (25%)
Query: 756 ESDDHPNVIRYYFSESTEKFMYIAVELCSASLEDVIEGSKGLAKNVAVQKNIDPINVLFQ 815
E HPN++RY+ E + MYI +E C EG+ + +Q+++ + Q
Sbjct: 1394 EGIKHPNLVRYFGVELHREEMYIFMEYCD-------EGTLEEVSRLGLQEHVIRLYSK-Q 1445
Query: 816 ITSGVNHLHSMKIVHRDLKPQNILIAPPKRYLSLHASKNKFRVLISDFGLCKKLEIDESS 875
IT +N LH IVHRD+K NI + + + + DFG KL+ + +
Sbjct: 1446 ITIAINVLHEHGIVHRDIKGANIFLT------------SSGLIKLGDFGCSVKLK-NNAQ 1492
Query: 876 FRTNNFNNPTGTSGWRAPEIISGEVSLSESFAXXXXXXXXXXXXXXLDVNHMDLVTKKRL 935
N+ GT+ + APE+I+
Sbjct: 1493 TMPGEVNSTLGTAAYMAPEVITRAKGEGHG------------------------------ 1522
Query: 936 TRAVDIFSLGCIFYYVLSKGEHPFGD-----RILREANILKGDYRLDGIKKSIQERSVCI 990
RA DI+SLGC+ +++ G+ P+ + +I+ + + G K I ER +
Sbjct: 1523 -RAADIWSLGCVVIEMVT-GKRPWHEYEHNFQIMYKVGM--------GHKPPIPER-LSP 1571
Query: 991 EAADLIKSMLEQNPLLRPASDEILKH 1016
E D + LE +P +R + ++L H
Sbjct: 1572 EGKDFLSHCLESDPKMRWTASQLLDH 1597
>Hs4758696 [T] KOG4721 Serine/threonine protein kinase contains leucine zipper
domain
Length = 966
Score = 64.3 bits (155), Expect = 1e-09
Identities = 57/186 (30%), Positives = 88/186 (46%), Gaps = 32/186 (17%)
Query: 715 LGYGSSGTVVFQGKFQNRPVAVKRLLIDFYDIASKEIQLLSESDDHPNVIRYYFSESTEK 774
LG G+ G V F GKF+ VA+K++ + + K ++ L HPN+I + +
Sbjct: 174 LGSGAQGAV-FLGKFRAEEVAIKKVR-EQNETDIKHLRKLK----HPNIIAFKGVCTQAP 227
Query: 775 FMYIAVELCS-ASLEDVIEGSKGLAKNVAVQKNIDPINVLFQITSGVNHLHSMKIVHRDL 833
I +E C+ L +V+ + + + V + I SG+N+LH KI+HRDL
Sbjct: 228 CYCIIMEYCAHGQLYEVLRAGRKITPRLLVDWSTG-------IASGMNYLHLHKIIHRDL 280
Query: 834 KPQNILIAPPKRYLSLHASKNKFRVLISDFGLCKKLEIDESSFRTNNFNNPTGTSGWRAP 893
K N+L+ + V ISDFG K+L D+S+ + GT W AP
Sbjct: 281 KSPNVLVT------------HTDAVKISDFGTSKELS-DKSTKMSF-----AGTVAWMAP 322
Query: 894 EIISGE 899
E+I E
Sbjct: 323 EVIRNE 328
>Hs4505695 [T] KOG0592 3-phosphoinositide-dependent protein kinase (PDK1)
Length = 556
Score = 64.3 bits (155), Expect = 1e-09
Identities = 80/328 (24%), Positives = 132/328 (39%), Gaps = 84/328 (25%)
Query: 713 RVLGYGSSGTVVFQGKFQ-NRPVAVKRLLIDFYDIASKEIQLLSESD-----DHPNVIRY 766
++LG GS TVV + +R A+K L +K + E D DHP ++
Sbjct: 86 KILGEGSFSTVVLARELATSREYAIKILEKRHIIKENKVPYVTRERDVMSRLDHPFFVKL 145
Query: 767 YFSESTEKFMYIAVELCSASLEDVIEGSKGLAKNVAVQKNIDPINVLF---QITSGVNHL 823
YF+ ++ +Y + + L K + + D F +I S + +L
Sbjct: 146 YFTFQDDEKLYFGLSYAK---------NGELLKYIRKIGSFDETCTRFYTAEIVSALEYL 196
Query: 824 HSMKIVHRDLKPQNILIAPPKRYLSLHASKNKFRVLISDFGLCKKLEIDESSFRTNNFNN 883
H I+HRDLKP+NIL+ + I+DFG K L + R N+F
Sbjct: 197 HGKGIIHRDLKPENILL------------NEDMHIQITDFGTAKVLSPESKQARANSF-- 242
Query: 884 PTGTSGWRAPEIISGEVSLSESFAXXXXXXXXXXXXXXLDVNHMDLVTKKRLTRAVDIFS 943
GT+ + +PE L+T+K ++ D+++
Sbjct: 243 -VGTAQYVSPE----------------------------------LLTEKSACKSSDLWA 267
Query: 944 LGCIFYYVLSKGEHPF--GDRILREANILKGDYRLDGIKKSIQERSVCIEAADLIKSMLE 1001
LGCI Y +++ G PF G+ L I+K +Y D +K +A DL++ +L
Sbjct: 268 LGCIIYQLVA-GLPPFRAGNEYLIFQKIIKLEY--DFPEKFFP------KARDLVEKLLV 318
Query: 1002 QNPLLRPASDE------ILKHPLFWGVS 1023
+ R +E + HP F V+
Sbjct: 319 LDATKRLGCEEMEGYGPLKAHPFFESVT 346
>Hs13899225 [R] KOG0586 Serine/threonine protein kinase
Length = 688
Score = 64.3 bits (155), Expect = 1e-09
Identities = 80/325 (24%), Positives = 131/325 (39%), Gaps = 78/325 (24%)
Query: 700 EQEGHLKHLSISSRVLGYGSSGTV-VFQGKFQNRPVAVKRLLIDFYDIASKEIQLL---- 754
E++ H+ + + R +G G+S V + + R VA+K +ID + +Q L
Sbjct: 51 EEQPHVGNYRLL-RTIGKGNSAKVKLARHILTGREVAIK--IIDKTQLNPSSLQKLFREV 107
Query: 755 --SESDDHPNVIRYYFSESTEKFMYIAVELCSASLEDVIEGSKGLAKNVAVQKNIDPINV 812
+ +HPN+++ + TEK +Y+ +E SA S G K +
Sbjct: 108 RIMKGLNHPNIVKLFEVIETEKTLYLVMEYASAGEVFDYLVSHGRMKEKEARAKFR---- 163
Query: 813 LFQITSGVNHLHSMKIVHRDLKPQNILIAPPKRYLSLHASKNKFRVLISDFGLCKKLEID 872
QI S V++ H IVHRDLK +N+L L A N + I+DFG + +
Sbjct: 164 --QIVSAVHYCHQKNIVHRDLKAENLL---------LDAEAN---IKIADFGFSNEFTLG 209
Query: 873 ESSFRTNNFNNPTGTSGWRAPEIISGEVSLSESFAXXXXXXXXXXXXXXLDVNHMDLVTK 932
+ + G+ + APE+ G K
Sbjct: 210 ------SKLDTFCGSPPYAAPELFQG---------------------------------K 230
Query: 933 KRLTRAVDIFSLGCIFYYVLSKGEHPFGDRILRE--ANILKGDYRLDGIKKSIQERSVCI 990
K VDI+SLG I Y ++S G PF L+E +L+G YR+ +
Sbjct: 231 KYDGPEVDIWSLGVILYTLVS-GSLPFDGHNLKELRERVLRGKYRVPFYMST-------- 281
Query: 991 EAADLIKSMLEQNPLLRPASDEILK 1015
+ +++ L NP R ++I+K
Sbjct: 282 DCESILRRFLVLNPAKRCTLEQIMK 306
>CE00847 [T] KOG0583 Serine/threonine protein kinase
Length = 622
Score = 64.3 bits (155), Expect = 1e-09
Identities = 73/268 (27%), Positives = 115/268 (42%), Gaps = 80/268 (29%)
Query: 760 HPNVIRYYFSESTEKFMYIAVELCSASLEDVIEGSKGLAKNVAVQKNIDPIN----VLFQ 815
HP++ R + ST +++ +EL S G + +K PI Q
Sbjct: 81 HPHITRLFRVISTPSDIFLVMELVSG----------GELFSYITRKGALPIRESRRYFQQ 130
Query: 816 ITSGVNHLHSMKIVHRDLKPQNILIAPPKRYLSLHASKNKFRVLISDFGLCKKLEIDESS 875
I SGV++ H+ IVHRDLKP+N+L L A+KN + I+DFGL S+
Sbjct: 131 IISGVSYCHNHMIVHRDLKPENLL---------LDANKN---IKIADFGL--------SN 170
Query: 876 FRTNN--FNNPTGTSGWRAPEIISGEVSLSESFAXXXXXXXXXXXXXXLDVNHMDLVTKK 933
+ T+ + G+ + APE+IS ++ +
Sbjct: 171 YMTDGDLLSTACGSPNYAAPELISNKLYVGPE---------------------------- 202
Query: 934 RLTRAVDIFSLGCIFYYVLSKGEHPFGDRILRE--ANILKGDYRLDGIKKSIQERSVCIE 991
VD++S G I Y +L G PF D+ + A I G Y + S+++ +
Sbjct: 203 -----VDLWSCGVILYAMLC-GTLPFDDQNVPTLFAKIKSGRYT---VPYSMEK-----Q 248
Query: 992 AADLIKSMLEQNPLLRPASDEILKHPLF 1019
AADLI +ML+ +P+ R I+ H F
Sbjct: 249 AADLISTMLQVDPVKRADVKRIVNHSWF 276
>At5g24430 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-Hand protein
superfamily
Length = 594
Score = 64.3 bits (155), Expect = 1e-09
Identities = 71/303 (23%), Positives = 124/303 (40%), Gaps = 74/303 (24%)
Query: 726 QGKFQNRPVAVKRL-------LIDFYDIASKEIQLLSESDDHPNVIRYYFSESTEKFMYI 778
+GK +N+ VAVK + + D+ +E++LL H +++++Y +++
Sbjct: 164 KGKMKNQTVAVKIISKAKMTSTLSIEDVR-REVKLLKALSGHRHMVKFYDVYEDADNVFV 222
Query: 779 AVELCSASLEDVIEGSKGLAKNVAV---QKNIDPINVLFQITSGVNHLHSMKIVHRDLKP 835
+ELC EG + L + +A +D +L QI S H +VHRDLKP
Sbjct: 223 VMELC--------EGGELLDRILARGGRYPEVDAKRILVQILSATAFFHLQGVVHRDLKP 274
Query: 836 QNILIAPPKRYLSLHASKNKFRVL-ISDFGLCKKLEIDESSFRTNNFNNPTGTSGWRAPE 894
+N L S+N+ +L + DFGL + D+ N+ G++ + APE
Sbjct: 275 ENFLF----------TSRNEDAILKVIDFGLSDFIRYDQ------RLNDVVGSAYYVAPE 318
Query: 895 IISGEVSLSESFAXXXXXXXXXXXXXXLDVNHMDLVTKKRLTRAVDIFSLGCIFYYVLSK 954
++ S D++S+G I Y +L
Sbjct: 319 VLHRSYSTE-----------------------------------ADMWSIGVISYILLC- 342
Query: 955 GEHPFGDRILREANILKGDYRLDGIKKSIQERSVCIEAADLIKSMLEQNPLLRPASDEIL 1014
G PF R E+ I + R + + + S+ A D +K +L ++ R + + L
Sbjct: 343 GSRPFYGR--TESAIFRCVLRANPNFEDMPWPSISPTAKDFVKRLLNKDHRKRMTAAQAL 400
Query: 1015 KHP 1017
HP
Sbjct: 401 AHP 403
>At4g36070 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-Hand protein
superfamily
Length = 536
Score = 64.3 bits (155), Expect = 1e-09
Identities = 77/317 (24%), Positives = 128/317 (40%), Gaps = 79/317 (24%)
Query: 713 RVLGYGSSG-TVVFQGKFQNRPVAVKRL-------LIDFYDIASKEIQLLSESDDHPNVI 764
++LG+G G T V VAVKR+ I+ D+ +E+++L H NV+
Sbjct: 75 KLLGHGQFGFTYVATDNNNGNRVAVKRIDKAKMTQPIEVEDV-KREVKILQALGGHENVV 133
Query: 765 RYYFSESTEKFMYIAVELC-SASLEDVIEGSKGLAKNVAVQKNIDPINVLFQITSGVNHL 823
++ + + ++YI +ELC L D I ++ K+ AV V+ Q+
Sbjct: 134 GFHNAFEDKTYIYIVMELCDGGELLDRILANRYTEKDAAV--------VVRQMLKVAAEC 185
Query: 824 HSMKIVHRDLKPQNILIAPPKRYLSLHASKNKFRVLISDFGLCKKLEIDESSFRTNNFNN 883
H +VHRD+KP+N L + SL A +DFGL ++ F +
Sbjct: 186 HLRGLVHRDMKPENFLFKSTEEGSSLKA---------TDFGLSDFIKPGV------KFQD 230
Query: 884 PTGTSGWRAPEIISGEVSLSESFAXXXXXXXXXXXXXXLDVNHMDLVTKKRLTRAVDIFS 943
G++ + APE++ K+R D++S
Sbjct: 231 IVGSAYYVAPEVL-----------------------------------KRRSGPESDVWS 255
Query: 944 LGCIFYYVLSKGEHPFGDR----ILREANILKGDYRLDGIKKSIQERSVCIEAADLIKSM 999
+G I Y +L G PF D+ I E K D+R + ++ A D +K +
Sbjct: 256 IGVITYILLC-GRRPFWDKTQDGIFNEVMRKKPDFR------EVPWPTISNGAKDFVKKL 308
Query: 1000 LEQNPLLRPASDEILKH 1016
L + P R + + L H
Sbjct: 309 LVKEPRARLTAAQALSH 325
>SPBC1604.14c [T] KOG0578 p21-activated serine/threonine protein kinase
Length = 658
Score = 63.9 bits (154), Expect = 1e-09
Identities = 78/310 (25%), Positives = 129/310 (41%), Gaps = 73/310 (23%)
Query: 715 LGYGSSGTVVFQGKF-QNRPVAVKRLLIDFY---DIASKEIQLLSESDDHPNVIRYYFSE 770
+G G+SG V + N VA+K++ I+ + EI L+ +S H N++ + +
Sbjct: 392 IGQGASGDVYSARQVGTNLSVAIKKMNINQQPKKEFIVNEI-LVMKSHHHKNIVNFIDTF 450
Query: 771 STEKFMYIAVE-LCSASLEDVIEGSKGLAKNVAVQKNIDPINVLFQITSGVNHLHSMKIV 829
+ +++ +E + SL +V+ + +A + + G+ HLH IV
Sbjct: 451 FYKSELWMVMEYMRGGSLTEVVTNNTLSEGQIAA--------ICKETLEGLQHLHENGIV 502
Query: 830 HRDLKPQNILIAPPKRYLSLHASKNKFRVLISDFGLCKKLEIDESSFRTNNFNNPTGTSG 889
HRD+K NIL LSL + ++DFG C +++ + + T GT
Sbjct: 503 HRDIKSDNIL-------LSLQGD-----IKLTDFGFCAQIDSNMTKRTT-----MVGTPY 545
Query: 890 WRAPEIISGEVSLSESFAXXXXXXXXXXXXXXLDVNHMDLVTKKRLTRAVDIFSLGCIFY 949
W APE+ VT+K VD++SLG I
Sbjct: 546 WMAPEV----------------------------------VTRKEYGFKVDVWSLG-IMA 570
Query: 950 YVLSKGEHPFGDRILREANILKGDYRLDGIKKSIQERSVCIEAA--DLIKSMLEQNPLLR 1007
+ +GE P+ L E N L+ Y + I R + + D + L NP R
Sbjct: 571 IEMVEGEPPY----LNE-NPLRALYLIATIGTPKISRPELLSSVFHDFLSKSLTVNPKQR 625
Query: 1008 PASDEILKHP 1017
P+S E+L+HP
Sbjct: 626 PSSGELLRHP 635
>Hs7706445 [T] KOG0664 Nemo-like MAPK-related serine/threonine protein kinase
Length = 515
Score = 63.9 bits (154), Expect = 1e-09
Identities = 68/259 (26%), Positives = 108/259 (41%), Gaps = 80/259 (30%)
Query: 713 RVLGYGSSGTV-VFQGKFQNRPVAVKRLLIDFYDIAS-----KEIQLLSESDDHPNVIRY 766
R +GYG+ G V + VA+K++ F ++ S +E+++L H NV+
Sbjct: 130 RPIGYGAFGVVWSVTDPRDGKRVALKKMPNVFQNLVSCKRVFRELKMLCFFK-HDNVLSA 188
Query: 767 ----------YFSESTEKFMYIAVELCSASLEDVIEGSKGLAKNVAVQKNIDPINV-LFQ 815
YF E +Y+ EL + L +I + L+ D + V L+Q
Sbjct: 189 LDILQPPHIDYFEE-----IYVVTELMQSDLHKIIVSPQPLSS--------DHVKVFLYQ 235
Query: 816 ITSGVNHLHSMKIVHRDLKPQNILIAPPKRYLSLHASKNKFRVLISDFGLCKKLEIDESS 875
I G+ +LHS I+HRD+KP N+L+ + + I DFGL + E+DES
Sbjct: 236 ILRGLKYLHSAGILHRDIKPGNLLV------------NSNCVLKICDFGLARVEELDESR 283
Query: 876 FRTNNFNNPTGTSGWRAPEIISGEVSLSESFAXXXXXXXXXXXXXXLDVNHMDLVTKKRL 935
T T +RAPEI+ G +
Sbjct: 284 HMTQE----VVTQYYRAPEILMG---------------------------------SRHY 306
Query: 936 TRAVDIFSLGCIFYYVLSK 954
+ A+DI+S+GCIF +L +
Sbjct: 307 SNAIDIWSVGCIFAELLGR 325
>Hs7705551 [T] KOG0661 MAPK related serine/threonine protein kinase
Length = 632
Score = 63.9 bits (154), Expect = 1e-09
Identities = 69/315 (21%), Positives = 129/315 (40%), Gaps = 46/315 (14%)
Query: 713 RVLGYGSSGTVVFQGKFQNRP-VAVKRLLIDFYD----IASKEIQLLSESDDHPNVIRYY 767
R LG G+ G+V+ ++ +A+K++ FY + +E++ L + + H NV++
Sbjct: 8 RQLGDGTYGSVLLGRSIESGELIAIKKMKRKFYSWEECMNQREVKSLKKLN-HANVVKLK 66
Query: 768 FSESTEKFMYIAVELCSASLEDVIEGSKGLAKNVAVQKNIDPINVLFQITSGVNHLHSMK 827
+Y E +L +I+ L A++ N+++QI G+ +H +
Sbjct: 67 EVIRENDHLYFIFEYMKENLYQLIKERNKLFPESAIR------NIMYQILQGLAFIHKLG 120
Query: 828 IVHRDLKPQNILIAPPKRYLSLHASKNKFRVLISDFGLCKKLEIDESSFRTNNFNNPTGT 887
HRDLKP+N+L P+ V I+DFGL +++ + + T
Sbjct: 121 FFHRDLKPENLLCMGPE------------LVKIADFGLAREIRSKPP------YTDYVST 162
Query: 888 SGWRAPEIISGEVSLSESFAXXXXXXXXXXXXXXLDVNHMDLVTKKRL---TRAVDIFSL 944
+RAPE++ + S + ++ T + L +D
Sbjct: 163 RWYRAPEVLLRSTNYSSPI-----------DVWAVGCIMAEVYTLRPLFPGASEIDTIFK 211
Query: 945 GCIFYYVLSKGEHPFGDRILREANILKGDYRLDGIKKSIQERSVCIEAADLIKSMLEQNP 1004
C K + P G ++ N + +K I S EA L++ ML+ +P
Sbjct: 212 ICQVLGTPKKTDWPEGYQLSSAMNFRWPQCVPNNLKTLIPNAS--SEAVQLLRDMLQWDP 269
Query: 1005 LLRPASDEILKHPLF 1019
RP + + L++P F
Sbjct: 270 KKRPTASQALRYPYF 284
>Hs5453860 [R] KOG0594 Protein kinase PCTAIRE and related kinases
Length = 496
Score = 63.9 bits (154), Expect = 1e-09
Identities = 75/356 (21%), Positives = 139/356 (38%), Gaps = 91/356 (25%)
Query: 715 LGYGSSGTVVF-QGKFQNRPVAVKRLLIDFYD----IASKEIQLLSESDDHPNVIRYYFS 769
LG G+ TV + K + VA+K + ++ + A +E+ LL + H N++ +
Sbjct: 171 LGEGTYATVYKGKSKLTDNLVALKEIRLEHEEGAPCTAIREVSLLKDLK-HANIVTLHDI 229
Query: 770 ESTEKFMYIAVELCSASLEDVIEGSKGLAKNVAVQKNIDPINVLFQITSGVNHLHSMKIV 829
TEK + + E L+ ++ N+ N+ LFQ+ G+ + H K++
Sbjct: 230 IHTEKSLTLVFEYLDKDLKQYLDD----CGNIINMHNVKLF--LFQLLRGLAYCHRQKVL 283
Query: 830 HRDLKPQNILIAPPKRYLSLHASKNKFRVLISDFGLCKKLEIDESSFRTNNFNNPTGTSG 889
HRDLKPQN+LI + + ++DFGL + S T ++N T
Sbjct: 284 HRDLKPQNLLI------------NERGELKLADFGLAR-----AKSIPTKTYSNEVVTLW 326
Query: 890 WRAPEIISGEVSLSESFAXXXXXXXXXXXXXXLDVNHMDLVTKKRLTRAVDIFSLGCIFY 949
+R P+I+ G S +D++ +GCIF
Sbjct: 327 YRPPDILLGSTDYSTQ---------------------------------IDMWGVGCIF- 352
Query: 950 YVLSKGEHPFGDRILRE-----------------ANILKGD---------YRLDGIKKSI 983
Y ++ G F + E IL + YR + +
Sbjct: 353 YEMATGRPLFPGSTVEEQLHFIFRILGTPTEETWPGILSNEEFKTYNYPKYRAEALLSHA 412
Query: 984 QERSVCIEAADLIKSMLEQNPLLRPASDEILKHPLFWGVSKKLEFLLKVSDRFEVE 1039
+ + ADL+ +L+ R ++++ +KHP F + +++ L + F ++
Sbjct: 413 PR--LDSDGADLLTKLLQFEGRNRISAEDAMKHPFFLSLGERIHKLPDTTSIFALK 466
>Hs15011928 [R] KOG0594 Protein kinase PCTAIRE and related kinases
Length = 448
Score = 63.9 bits (154), Expect = 1e-09
Identities = 75/356 (21%), Positives = 139/356 (38%), Gaps = 91/356 (25%)
Query: 715 LGYGSSGTVVF-QGKFQNRPVAVKRLLIDFYD----IASKEIQLLSESDDHPNVIRYYFS 769
LG G+ TV + K + VA+K + ++ + A +E+ LL + H N++ +
Sbjct: 123 LGEGTYATVYKGKSKLTDNLVALKEIRLEHEEGAPCTAIREVSLLKDLK-HANIVTLHDI 181
Query: 770 ESTEKFMYIAVELCSASLEDVIEGSKGLAKNVAVQKNIDPINVLFQITSGVNHLHSMKIV 829
TEK + + E L+ ++ N+ N+ LFQ+ G+ + H K++
Sbjct: 182 IHTEKSLTLVFEYLDKDLKQYLDD----CGNIINMHNVKLF--LFQLLRGLAYCHRQKVL 235
Query: 830 HRDLKPQNILIAPPKRYLSLHASKNKFRVLISDFGLCKKLEIDESSFRTNNFNNPTGTSG 889
HRDLKPQN+LI + + ++DFGL + S T ++N T
Sbjct: 236 HRDLKPQNLLI------------NERGELKLADFGLAR-----AKSIPTKTYSNEVVTLW 278
Query: 890 WRAPEIISGEVSLSESFAXXXXXXXXXXXXXXLDVNHMDLVTKKRLTRAVDIFSLGCIFY 949
+R P+I+ G S +D++ +GCIF
Sbjct: 279 YRPPDILLGSTDYSTQ---------------------------------IDMWGVGCIF- 304
Query: 950 YVLSKGEHPFGDRILRE-----------------ANILKGD---------YRLDGIKKSI 983
Y ++ G F + E IL + YR + +
Sbjct: 305 YEMATGRPLFPGSTVEEQLHFIFRILGTPTEETWPGILSNEEFKTYNYPKYRAEALLSHA 364
Query: 984 QERSVCIEAADLIKSMLEQNPLLRPASDEILKHPLFWGVSKKLEFLLKVSDRFEVE 1039
+ + ADL+ +L+ R ++++ +KHP F + +++ L + F ++
Sbjct: 365 PR--LDSDGADLLTKLLQFEGRNRISAEDAMKHPFFLSLGERIHKLPDTTSIFALK 418
>At5g66210 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-Hand protein
superfamily
Length = 523
Score = 63.9 bits (154), Expect = 1e-09
Identities = 79/312 (25%), Positives = 128/312 (40%), Gaps = 66/312 (21%)
Query: 713 RVLGYGSSG-TVVFQGKFQNRPVAVKRL------LIDFYDIASKEIQLLSESDDHPNVIR 765
++LG+G G T V + VAVKRL L + +E+Q+L H NV++
Sbjct: 66 KLLGHGQFGYTYVAIHRPNGDRVAVKRLDKSKMVLPIAVEDVKREVQILIALSGHENVVQ 125
Query: 766 YYFSESTEKFMYIAVELC-SASLEDVIEGSKGLAKNVAVQKNIDPINVLFQITSGVNHLH 824
++ + + ++YI +ELC L D I KG N +K+ + +G HLH
Sbjct: 126 FHNAFEDDDYVYIVMELCEGGELLDRILSKKG---NRYSEKDAAVVVRQMLKVAGECHLH 182
Query: 825 SMKIVHRDLKPQNILIAPPKRYLSLHASKNKFRVLISDFGLCKKLEIDESSFRTNNFNNP 884
+VHRD+KP+N L + L A +DFGL ++ + F++
Sbjct: 183 G--LVHRDMKPENFLFKSAQLDSPLKA---------TDFGLSDFIKPGK------RFHDI 225
Query: 885 TGTSGWRAPEIISGEVSLSESFAXXXXXXXXXXXXXXLDVNHMDLVTKKRLTRAVDIFSL 944
G++ + APE++ K+R D++S+
Sbjct: 226 VGSAYYVAPEVL-----------------------------------KRRSGPESDVWSI 250
Query: 945 GCIFYYVLSKGEHPFGDRILREANILKGDYRLDGIKKSIQERSVCIEAADLIKSMLEQNP 1004
G I Y +L G PF DR E I K R ++ A D +K +L ++P
Sbjct: 251 GVITYILLC-GRRPFWDR--TEDGIFKEVLRNKPDFSRKPWATISDSAKDFVKKLLVKDP 307
Query: 1005 LLRPASDEILKH 1016
R + + L H
Sbjct: 308 RARLTAAQALSH 319
>At5g39440 [T] KOG0583 Serine/threonine protein kinase
Length = 494
Score = 63.9 bits (154), Expect = 1e-09
Identities = 74/263 (28%), Positives = 104/263 (39%), Gaps = 71/263 (26%)
Query: 760 HPNVIRYYFSESTEKFMYIAVELC-SASLEDVIEGSKGLAKNVAVQKNIDPINVLFQITS 818
HP++IR Y T +Y+ +E S L D I L ++ A ++ QI S
Sbjct: 76 HPHIIRQYEVIETPNDIYVVMEYVKSGELFDYIVEKGKLQEDEAR-------HLFQQIIS 128
Query: 819 GVNHLHSMKIVHRDLKPQNILIAPPKRYLSLHASKNKFRVLISDFGLCKKLEIDESSFRT 878
GV + H IVHRDLKP+N+L+ ++ + I DFGL + D +T
Sbjct: 129 GVEYCHRNMIVHRDLKPENVLL------------DSQCNIKIVDFGLSNVMH-DGHFLKT 175
Query: 879 NNFNNPTGTSGWRAPEIISGEVSLSESFAXXXXXXXXXXXXXXLDVNHMDLVTKKRLTRA 938
+ G+ + APE+ISG K
Sbjct: 176 S-----CGSPNYAAPEVISG----------------------------------KPYGPD 196
Query: 939 VDIFSLGCIFYYVLSKGEHPFGDRILREA--NILKGDYRLDGIKKSIQERSVCIEAADLI 996
VDI+S G I Y +L G PF D + I +G Y L A DLI
Sbjct: 197 VDIWSCGVILYALLC-GTLPFDDENIPNVFEKIKRGMYTLPNHLSHF--------ARDLI 247
Query: 997 KSMLEQNPLLRPASDEILKHPLF 1019
ML +P +R + EI +HP F
Sbjct: 248 PRMLMVDPTMRISITEIRQHPWF 270
>At3g08720 [RT] KOG0598 Ribosomal protein S6 kinase and related proteins
Length = 471
Score = 63.9 bits (154), Expect = 1e-09
Identities = 71/276 (25%), Positives = 117/276 (41%), Gaps = 74/276 (26%)
Query: 759 DHPNVIRYYFSESTEKFMYIAVELCSASLEDVIEGSKGLAKNVAVQKNIDPINVLFQITS 818
DHP +++ +S T+ +Y+ ++ + +GL + + +I S
Sbjct: 196 DHPFIVQLKYSFQTKYRLYLVLDFINGGHLFFQLYHQGLFREDLARV------YTAEIVS 249
Query: 819 GVNHLHSMKIVHRDLKPQNILIAPPKRYLSLHASKNKFRVLISDFGLCKKLEIDESSFRT 878
V+HLH I+HRDLKP+NIL+ V+++DFGL K+ E + S
Sbjct: 250 AVSHLHEKGIMHRDLKPENILMDVDG------------HVMLTDFGLAKEFEENTRS--- 294
Query: 879 NNFNNPTGTSGWRAPEIISGEVSLSESFAXXXXXXXXXXXXXXLDVNHMDLVTKKRLTRA 938
N+ GT+ + APEI+ G K +A
Sbjct: 295 ---NSMCGTTEYMAPEIVRG----------------------------------KGHDKA 317
Query: 939 VDIFSLGCIFYYVLSKGEHPF-GDRILREANILKGDYRLDGIKKSIQERSVCIEAADLIK 997
D +S+G + Y +L+ G+ PF G + + I+K +L + EA L+K
Sbjct: 318 ADWWSVGILLYEMLT-GKPPFLGSKGKIQQKIVKDKIKLPQFLSN--------EAHALLK 368
Query: 998 SMLEQNPLLRPAS-----DEILKHPLFWGVS-KKLE 1027
+L++ P R S +EI KH F ++ KKLE
Sbjct: 369 GLLQKEPERRLGSGPSGAEEIKKHKWFKAINWKKLE 404
>YHR102w [T] KOG0201 Serine/threonine protein kinase
Length = 1080
Score = 63.5 bits (153), Expect = 2e-09
Identities = 78/324 (24%), Positives = 134/324 (41%), Gaps = 75/324 (23%)
Query: 702 EGHLKHLSISSR--VLGYGSSGTVVFQGKF--QNRPVAVKRLLIDF----YDIASKEIQL 753
EG + S+ R V+G G G VV++G R A+K L +D + +EIQ
Sbjct: 14 EGEMDVSSLFKRTEVIGRGKFG-VVYKGYNVKTGRVYAIKVLNLDSDSDEVEDVQREIQF 72
Query: 754 LSESDDHPNVIRYYFSESTEKFMYIAVELCS-ASLEDVIEGSKGLAKNVAVQKNIDPINV 812
L+ N+ RYY S + ++I +E C+ SL ++ K K + V +
Sbjct: 73 LASLKQISNITRYYGSYLKDTSLWIIMEHCAGGSLRSLLRPGKIDEKYIGV--------I 124
Query: 813 LFQITSGVNHLHSMKIVHRDLKPQNILIAPPKRYLSLHASKNKFRVLISDFGLCKKLEID 872
+ ++ + +H ++HRD+K N+LI N+ V + DFG+ +++
Sbjct: 125 MRELLVALKCIHKDNVIHRDIKAANVLIT------------NEGNVKLCDFGVA--AQVN 170
Query: 873 ESSFRTNNFNNPTGTSGWRAPEIISGEVSLSESFAXXXXXXXXXXXXXXLDVNHMDLVTK 932
++S R GT W APE+I V
Sbjct: 171 QTSLRRQTM---AGTPYWMAPEVIMEGVYYDTK--------------------------- 200
Query: 933 KRLTRAVDIFSLGCIFYYVLSKGEHPFGD-RILREANILKGDYRLDGIKKSIQERSVCIE 991
VDI+SLG I Y ++ G P+ D LR ++ + +++RS
Sbjct: 201 ------VDIWSLG-ITTYEIATGNPPYCDVEALRAMQLI-----IKSKPPRLEDRSYSTS 248
Query: 992 AADLIKSMLEQNPLLRPASDEILK 1015
+ I L+++P R ++D++LK
Sbjct: 249 LKEFIALCLDEDPKERLSADDLLK 272
>SPBC16E9.13 [T] KOG0583 Serine/threonine protein kinase
Length = 474
Score = 63.5 bits (153), Expect = 2e-09
Identities = 59/192 (30%), Positives = 84/192 (43%), Gaps = 30/192 (15%)
Query: 713 RVLGYGSSGTVVFQGKFQNRP------VAVKRLLIDFYDIASKEIQLLSE--SDDHPNVI 764
R L GS GTVV + P A+K + Y +E+ +L + H N+I
Sbjct: 13 RPLNKGSYGTVVLAHRLFRTPRCKDLKYAIKCIKKPAYTFL-QEVNILRQLSRSRHRNII 71
Query: 765 RYYFSESTEKFMYIAVELCSAS--LEDVIEGSKGLAKNVAVQKNIDPINVLFQITSGVNH 822
+ S + Y+ +E C E ++ AKN N+ QI GV H
Sbjct: 72 HFVESFEDNVYYYVVLEYCPLGDLYECILNNDFPNAKNQPEMIK----NIFLQIIDGVAH 127
Query: 823 LHSMKIVHRDLKPQNILIAPPKRYLSLHASKNKFRVLISDFGLCKKLEIDESSFRTNNFN 882
LHS I HRDLKP+N L LSL ++ V ISDFGL + +I +++
Sbjct: 128 LHSHGIYHRDLKPENFL-------LSLSEDGSELVVKISDFGLACRDKI--------SYD 172
Query: 883 NPTGTSGWRAPE 894
TG+ + APE
Sbjct: 173 FGTGSDRYMAPE 184
>HsM5454184 [T] KOG4721 Serine/threonine protein kinase contains leucine zipper
domain
Length = 859
Score = 63.5 bits (153), Expect = 2e-09
Identities = 58/186 (31%), Positives = 90/186 (48%), Gaps = 32/186 (17%)
Query: 715 LGYGSSGTVVFQGKFQNRPVAVKRLLIDFYDIASKEIQLLSESDDHPNVIRYYFSESTEK 774
+G G+ G V F G+F VAVK++ D+ +I+ L + HPN+I + +
Sbjct: 131 VGSGAQGAV-FLGRFHGEEVAVKKVR----DLKETDIKHLRKLK-HPNIITFKGVCTQAP 184
Query: 775 FMYIAVELCS-ASLEDVIEGSKGLAKNVAVQKNIDPINVLFQITSGVNHLHSMKIVHRDL 833
I +E C+ L +V+ + + ++ V ++ I G+N+LH KI+HRDL
Sbjct: 185 CYCILMEFCAQGQLYEVLRAGRPVTPSLLVDWSMG-------IAGGMNYLHLHKIIHRDL 237
Query: 834 KPQNILIAPPKRYLSLHASKNKFRVLISDFGLCKKLEIDESSFRTNNFNNPTGTSGWRAP 893
K N+LI Y + V ISDFG K+L D+S+ + GT W AP
Sbjct: 238 KSPNMLIT----YDDV--------VKISDFGTSKELS-DKSTKMSF-----AGTVAWMAP 279
Query: 894 EIISGE 899
E+I E
Sbjct: 280 EVIRNE 285
>Hs7657335 [T] KOG0587 Traf2- and Nck-interacting kinase and related germinal
center kinase (GCK) family protein kinases
Length = 1295
Score = 63.5 bits (153), Expect = 2e-09
Identities = 53/195 (27%), Positives = 92/195 (47%), Gaps = 34/195 (17%)
Query: 714 VLGYGSSGTVVFQGKF----QNRPVAVKRLLIDFYDIASKEIQLLSESDDHPNVIRYYFS 769
V+G G+ G V ++G+ Q + V + D + +EI +L + H N+ YY +
Sbjct: 30 VVGNGTYGQV-YKGRHVKTGQLAAIKVMDVTEDEEEEIKQEINMLKKYSHHRNIATYYGA 88
Query: 770 ------ESTEKFMYIAVELCSA-SLEDVIEGSKGLAKNVAVQKNIDPINVLFQITSGVNH 822
+ +++ +E C A S+ D+++ +KG A K + +I G+ H
Sbjct: 89 FIKKSPPGNDDQLWLVMEFCGAGSVTDLVKNTKGNAL-----KEDCIAYICREILRGLAH 143
Query: 823 LHSMKIVHRDLKPQNILIAPPKRYLSLHASKNKFRVLISDFGLCKKLEIDESSFRTNNFN 882
LH+ K++HRD+K QN+L+ V + DFG+ ++D + R N F
Sbjct: 144 LHAHKVIHRDIKGQNVLLT------------ENAEVKLVDFGV--SAQLDRTVGRRNTF- 188
Query: 883 NPTGTSGWRAPEIIS 897
GT W APE+I+
Sbjct: 189 --IGTPYWMAPEVIA 201
>Hs4826878 [T] KOG0582 Ste20-like serine/threonine protein kinase
Length = 527
Score = 63.5 bits (153), Expect = 2e-09
Identities = 84/350 (24%), Positives = 145/350 (41%), Gaps = 71/350 (20%)
Query: 718 GSSGTVVFQGKF---QNRPVAVKRLLID----FYDIASKEIQLLSESDDHPNVIRYYFSE 770
GS T V Q + + VA+KR+ ++ D KEIQ +S+ HPN++ YY S
Sbjct: 24 GSGATAVVQAAYCAPKKEKVAIKRINLEKCQTSMDELLKEIQAMSQCH-HPNIVSYYTSF 82
Query: 771 STEKFMYIAVELCSA-SLEDVIEG--SKGLAKNVAVQKNIDPINVLFQITSGVNHLHSMK 827
+ +++ ++L S S+ D+I+ +KG K+ + ++ +L ++ G+ +LH
Sbjct: 83 VVKDELWLVMKLLSGGSVLDIIKHIVAKGEHKSGVLDESTIA-TILREVLEGLEYLHKNG 141
Query: 828 IVHRDLKPQNILIAPPKRYLSLHASKNKFRVLISDFGLCKKLEIDESSFRTNNFNNPTGT 887
+HRD+K NIL+ V I+DFG+ L R GT
Sbjct: 142 QIHRDVKAGNILLG------------EDGSVQIADFGVSAFLATGGDITRNKVRKTFVGT 189
Query: 888 SGWRAPEIISGEVSLSESFAXXXXXXXXXXXXXXLDVNHMDLVTKKRLTRAVDIFSLGCI 947
W APE++ V D DI+S G I
Sbjct: 190 PCWMAPEVME-------------------------QVRGYDF--------KADIWSFG-I 215
Query: 948 FYYVLSKGEHPFGDRILREANILKGDYRLDGIKKSIQERSVCIEAADLIKSM----LEQN 1003
L+ G P+ + +L ++ +Q++ + + + M L+++
Sbjct: 216 TAIELATGAAPYHKYPPMKVLMLTLQNDPPSLETGVQDKEMLKKYGKSFRKMISLCLQKD 275
Query: 1004 PLLRPASDEILKHPLFWGVSKKLEFLLK--------VSDRFEVERRDPPS 1045
P RP + E+L+H F+ +K EFL + +S+R + RR P S
Sbjct: 276 PEKRPTAAELLRHK-FFQKAKNKEFLQEKTLQRAPTISERAKKVRRVPGS 324
>Hs4506075 [T] KOG4236 Serine/threonine protein kinase PKC mu/PKD and related
proteins
Length = 912
Score = 63.5 bits (153), Expect = 2e-09
Identities = 91/344 (26%), Positives = 145/344 (41%), Gaps = 81/344 (23%)
Query: 714 VLGYGSSGTVVFQGKFQN--RPVAVKRLLIDFYDIASK-EIQLLSE-----SDDHPNVIR 765
VLG G G +V+ GK + R VA+K +ID +K E QL +E + HP V+
Sbjct: 588 VLGSGQFG-IVYGGKHRKTGRDVAIK--IIDKLRFPTKQESQLRNEVAILQNLHHPGVVN 644
Query: 766 YYFSESTEKFMYIAVE-LCSASLEDVIEGSKGLAKNVAVQKNIDPINVLFQITSGVNHLH 824
T + +++ +E L LE ++ KG + ++I ++ QI + HLH
Sbjct: 645 LECMFETPERVFVVMEKLHGDMLEMILSSEKG-----RLPEHITKF-LITQILVALRHLH 698
Query: 825 SMKIVHRDLKPQNILIAPPKRYLSLHASKNKF-RVLISDFGLCKKLEIDESSFRTNNFNN 883
IVH DLKP+N+L+ AS + F +V + DFG + I E SFR +
Sbjct: 699 FKNIVHCDLKPENVLL----------ASADPFPQVKLCDFGFAR--IIGEKSFR----RS 742
Query: 884 PTGTSGWRAPEIISGEVSLSESFAXXXXXXXXXXXXXXLDVNHMDLVTKKRLTRAVDIFS 943
GT + APE++ K R++D++S
Sbjct: 743 VVGTPAYLAPEVL----------------------------------RNKGYNRSLDMWS 768
Query: 944 LGCIFYYVLSKGEHPFGDRILREANILKGDYRLDGIKKSIQERSVCIEAADLIKSMLEQN 1003
+G I Y LS G PF + + +I + + + EA DLI ++L+
Sbjct: 769 VGVIIYVSLS-GTFPFNE----DEDIHDQIQNAAFMYPPNPWKEISHEAIDLINNLLQVK 823
Query: 1004 PLLRPASDEILKHPLF-----WGVSKKLEFLLKVSDRFEVERRD 1042
R + D+ L HP W ++LE K+ +R+ D
Sbjct: 824 MRKRYSVDKTLSHPWLQDYQTWLDLRELE--CKIGERYITHESD 865
>Hs21735552 [T] KOG4721 Serine/threonine protein kinase contains leucine zipper
domain
Length = 859
Score = 63.5 bits (153), Expect = 2e-09
Identities = 58/186 (31%), Positives = 90/186 (48%), Gaps = 32/186 (17%)
Query: 715 LGYGSSGTVVFQGKFQNRPVAVKRLLIDFYDIASKEIQLLSESDDHPNVIRYYFSESTEK 774
+G G+ G V F G+F VAVK++ D+ +I+ L + HPN+I + +
Sbjct: 131 VGSGAQGAV-FLGRFHGEEVAVKKVR----DLKETDIKHLRKLK-HPNIITFKGVCTQAP 184
Query: 775 FMYIAVELCS-ASLEDVIEGSKGLAKNVAVQKNIDPINVLFQITSGVNHLHSMKIVHRDL 833
I +E C+ L +V+ + + ++ V ++ I G+N+LH KI+HRDL
Sbjct: 185 CYCILMEFCAQGQLYEVLRAGRPVTPSLLVDWSMG-------IAGGMNYLHLHKIIHRDL 237
Query: 834 KPQNILIAPPKRYLSLHASKNKFRVLISDFGLCKKLEIDESSFRTNNFNNPTGTSGWRAP 893
K N+LI Y + V ISDFG K+L D+S+ + GT W AP
Sbjct: 238 KSPNMLIT----YDDV--------VKISDFGTSKELS-DKSTKMSF-----AGTVAWMAP 279
Query: 894 EIISGE 899
E+I E
Sbjct: 280 EVIRNE 285
>CE20564 [T] KOG0578 p21-activated serine/threonine protein kinase
Length = 540
Score = 63.5 bits (153), Expect = 2e-09
Identities = 69/311 (22%), Positives = 132/311 (42%), Gaps = 71/311 (22%)
Query: 715 LGYGSSGTVVFQGKFQNRP-VAVKRLLI---DFYDIASKEIQLLSESDDHPNVIRYYFSE 770
+G GS+G V K + VAVKR+ + ++ E+ +L + HPN++R++ S
Sbjct: 255 IGEGSTGVVEAAYKISTKQIVAVKRMNLRKQQRRELLFNEVSILRQYQ-HPNIVRFFSSH 313
Query: 771 STEKFMYIAVELCSA-SLEDVIEGSKGLAKNVAVQKNIDPINVLFQITSGVNHLHSMKIV 829
+ +++ +E SL D++ ++ +A + Q+ ++ LH+ K++
Sbjct: 314 LVDDELWVVMEFMEGGSLTDIVTATRMTEPQIAT--------ISRQVLGALDFLHARKVI 365
Query: 830 HRDLKPQNILIAPPKRYLSLHASKNKFRVLISDFGLCKKLEIDESSFRTNNFNNPTGTSG 889
HRD+K +IL+ K V ++DFG C +L + R + GT
Sbjct: 366 HRDIKSDSILL------------KRDGTVKLTDFGFCGQLSEEVPRRR-----SLVGTPY 408
Query: 890 WRAPEIISGEVSLSESFAXXXXXXXXXXXXXXLDVNHMDLVTKKRLTRAVDIFSLGCIFY 949
W A E+I+ E TRA DI+S G I
Sbjct: 409 WTAAEVIARE---------------------------------PYDTRA-DIWSFG-IML 433
Query: 950 YVLSKGEHP-FGDRILREANILKGDYRLDGIKKSIQERSVCIEAADLIKSMLEQNPLLRP 1008
+ +GE P F D+ + ++ ++ + + V +E ++L+ + ++ R
Sbjct: 434 IEMVEGEPPFFNDQPFQAMKRIRDEHE----ARFSRHAKVSVELSELLSHCIVKDVNKRW 489
Query: 1009 ASDEILKHPLF 1019
+ ++L+HP F
Sbjct: 490 PAKDLLRHPFF 500
>CE05425 [T] KOG0578 p21-activated serine/threonine protein kinase
Length = 542
Score = 63.5 bits (153), Expect = 2e-09
Identities = 69/311 (22%), Positives = 132/311 (42%), Gaps = 71/311 (22%)
Query: 715 LGYGSSGTVVFQGKFQNRP-VAVKRLLI---DFYDIASKEIQLLSESDDHPNVIRYYFSE 770
+G GS+G V K + VAVKR+ + ++ E+ +L + HPN++R++ S
Sbjct: 257 IGEGSTGVVEAAYKISTKQIVAVKRMNLRKQQRRELLFNEVSILRQYQ-HPNIVRFFSSH 315
Query: 771 STEKFMYIAVELCSA-SLEDVIEGSKGLAKNVAVQKNIDPINVLFQITSGVNHLHSMKIV 829
+ +++ +E SL D++ ++ +A + Q+ ++ LH+ K++
Sbjct: 316 LVDDELWVVMEFMEGGSLTDIVTATRMTEPQIAT--------ISRQVLGALDFLHARKVI 367
Query: 830 HRDLKPQNILIAPPKRYLSLHASKNKFRVLISDFGLCKKLEIDESSFRTNNFNNPTGTSG 889
HRD+K +IL+ K V ++DFG C +L + R + GT
Sbjct: 368 HRDIKSDSILL------------KRDGTVKLTDFGFCGQLSEEVPRRR-----SLVGTPY 410
Query: 890 WRAPEIISGEVSLSESFAXXXXXXXXXXXXXXLDVNHMDLVTKKRLTRAVDIFSLGCIFY 949
W A E+I+ E TRA DI+S G I
Sbjct: 411 WTAAEVIARE---------------------------------PYDTRA-DIWSFG-IML 435
Query: 950 YVLSKGEHP-FGDRILREANILKGDYRLDGIKKSIQERSVCIEAADLIKSMLEQNPLLRP 1008
+ +GE P F D+ + ++ ++ + + V +E ++L+ + ++ R
Sbjct: 436 IEMVEGEPPFFNDQPFQAMKRIRDEHE----ARFSRHAKVSVELSELLSHCIVKDVNKRW 491
Query: 1009 ASDEILKHPLF 1019
+ ++L+HP F
Sbjct: 492 PAKDLLRHPFF 502
>At5g66850 [T] KOG0198 MEKK and related serine/threonine protein kinases
Length = 376
Score = 63.5 bits (153), Expect = 2e-09
Identities = 68/269 (25%), Positives = 109/269 (40%), Gaps = 59/269 (21%)
Query: 749 KEIQLLSESDDHPNVIRYYFSESTEKFMYIAVELCS-ASLEDVIEGSKGLAKNVAVQKNI 807
+EI+LLS HPN+++Y+ SE+ E +I +E S+ I G V+
Sbjct: 54 QEIKLLSNLQ-HPNIVQYFGSETVEDRFFIYLEYVHPGSINKYIRDHCGTMTESVVR--- 109
Query: 808 DPINVLFQITSGVNHLHSMKIVHRDLKPQNILIAPPKRYLSLHASKNKFRVLISDFGLCK 867
N I SG+ +LH+ K VHRD+K N+L+ V ++DFG+ K
Sbjct: 110 ---NFTRHILSGLAYLHNKKTVHRDIKGANLLV------------DASGVVKLADFGMAK 154
Query: 868 KLEIDESSFRTNNFNNPTGTSGWRAPEIISGEVSLSESFAXXXXXXXXXXXXXXLDVNHM 927
L + G+ W APE++ V +S
Sbjct: 155 HLTGQRADLSLK------GSPYWMAPEVLMQAVMQKDS---------------------- 186
Query: 928 DLVTKKRLTRAVDIFSLGCIFYYVLSKGEHPFGDRILREANILKGDYRLDGIKKSIQERS 987
L AVDI+SLGC + + G+ P+ E +++ I E S
Sbjct: 187 ----NPDLAFAVDIWSLGCTIIEMFT-GKPPWS-----EFEGAAAMFKVMRDSPPIPE-S 235
Query: 988 VCIEAADLIKSMLEQNPLLRPASDEILKH 1016
+ E D ++ ++NP RP + +L+H
Sbjct: 236 MSPEGKDFLRLCFQRNPAERPTASMLLEH 264
>At5g26751 [G] KOG0658 Glycogen synthase kinase-3
Length = 413
Score = 63.5 bits (153), Expect = 2e-09
Identities = 83/340 (24%), Positives = 146/340 (42%), Gaps = 86/340 (25%)
Query: 710 ISSRVLGYGSSGTVVFQGKF--QNRPVAVKRLLIDFYDIASKEIQLLSESDDHPNVI--R 765
++ RV+G+GS G VVFQ K VA+K++L D ++E+Q + D HPNV+ +
Sbjct: 70 MAERVVGHGSFG-VVFQAKCLETGETVAIKKVLQD-RRYKNRELQTMRLLD-HPNVVSLK 126
Query: 766 YYFSESTEK---FMYIAVELCSASLEDVIEGSKGLAKNVAVQKNIDPINVLFQITSGVNH 822
+ F +TEK ++ + +E ++ VI+ L + + + I +QI +++
Sbjct: 127 HCFFSTTEKDELYLNLVLEYVPETVHRVIKHYNKLNQRMPL---IYVKLYTYQIFRALSY 183
Query: 823 LHS-MKIVHRDLKPQNILIAPPKRYLSLHASKNKFRVLISDFGLCKKLEIDESSFRTNNF 881
+H + + HRD+KPQN+L+ P + +V + DFG K L E +
Sbjct: 184 IHRCIGVCHRDIKPQNLLVNP-----------HTHQVKLCDFGSAKVLVKGEPNI----- 227
Query: 882 NNPTGTSGWRAPEIISGEVSLSESFAXXXXXXXXXXXXXXLDVNHMDLVTKKRLTRAVDI 941
+ + +RAPE+I G T A+D+
Sbjct: 228 -SYICSRYYRAPELIFGAT---------------------------------EYTTAIDV 253
Query: 942 FSLGCIF-YYVLSKGEHPFGDRILREANILK-----------------GDYRLDGIK--- 980
+S GC+ +L + P + + I+K +++ IK
Sbjct: 254 WSAGCVLAELLLGQPLFPGESGVDQLVEIIKVLGTPTREEIKCMNPNYTEFKFPQIKAHP 313
Query: 981 -KSIQERSVCIEAADLIKSMLEQNPLLRPASDEILKHPLF 1019
I + + EA DL+ +L+ +P LR A+ + L HP F
Sbjct: 314 WHKIFHKRMPPEAVDLVSRLLQYSPNLRSAALDTLVHPFF 353
>At3g56760 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-Hand protein
superfamily
Length = 577
Score = 63.5 bits (153), Expect = 2e-09
Identities = 73/306 (23%), Positives = 125/306 (39%), Gaps = 72/306 (23%)
Query: 726 QGKFQNRPVAVKRL-------LIDFYDIASKEIQLLSESDDHPNVIRYYFSESTEKFMYI 778
+G + + VAVK + I D+ +E+++L H N++++Y + ++ +YI
Sbjct: 145 KGSLKGQDVAVKVIPKSKMTTAIAIEDVR-REVKILRALTGHKNLVQFYDAFEDDENVYI 203
Query: 779 AVELCSAS--LEDVIE-GSKGLAKNVAVQKNIDPINVLFQITSGVNHLHSMKIVHRDLKP 835
+ELC L+ +++ G K +D V+ QI S V + H +VHRDLKP
Sbjct: 204 VMELCQGGELLDKILQRGGK--------YSEVDAKKVMIQILSVVAYCHLQGVVHRDLKP 255
Query: 836 QNILIAPPKRYLSLHASKNKFRVLISDFGLCKKLEIDESSFRTNNFNNPTGTSGWRAPEI 895
+N L L A DFGL + DE N+ G++ + APE+
Sbjct: 256 ENFLFTTKDESSPLKA---------IDFGLSDYVRPDE------RLNDIVGSAYYVAPEV 300
Query: 896 ISGEVSLSESFAXXXXXXXXXXXXXXLDVNHMDLVTKKRLTRAVDIFSLGCIFYYVLSKG 955
+ H T+ D++S+G I Y +L G
Sbjct: 301 L-----------------------------HRTYGTE------ADMWSIGVIAYILLC-G 324
Query: 956 EHPFGDRILREANILKGDYRLDGIKKSIQERSVCIEAADLIKSMLEQNPLLRPASDEILK 1015
PF R E+ I + + + + S+ +A D +K +L ++ R + + L
Sbjct: 325 SRPFWAR--SESGIFRAVLKAEPNFEEAPWPSLSPDAVDFVKRLLNKDYRKRLTAAQALC 382
Query: 1016 HPLFWG 1021
HP G
Sbjct: 383 HPWLVG 388
>At1g07880 [T] KOG0660 Mitogen-activated protein kinase
Length = 363
Score = 63.5 bits (153), Expect = 2e-09
Identities = 87/338 (25%), Positives = 132/338 (38%), Gaps = 94/338 (27%)
Query: 715 LGYGSSGTVVFQGKFQ-NRPVAVKRLLIDFYDIAS-----KEIQLLSESDDHPNVIRYY- 767
+G G+ G V + N VA+K++ F + +EI+LLS D H NVI+
Sbjct: 39 IGRGAYGIVCCATNSETNEEVAIKKIANAFDNRVDAKRTLREIKLLSHMD-HDNVIKIKD 97
Query: 768 FSESTEKF----MYIAVELCSASLEDVIEGSKGLAKNVAVQKNIDPINVLFQITSGVNHL 823
E EK +YI EL L +I ++ L + L+QI G+ ++
Sbjct: 98 IIELPEKERFEDVYIVYELMDTDLHQIIRSTQTLTDDHCQY-------FLYQILRGLKYI 150
Query: 824 HSMKIVHRDLKPQNILIAPPKRYLSLHASKNKFRVLISDFGLCKKLEIDESSFRTNNFNN 883
HS ++HRDLKP N+++ + I DFGL + +S T
Sbjct: 151 HSANVLHRDLKPSNLVL------------NTNCDLKICDFGLAR------TSNETEIMTE 192
Query: 884 PTGTSGWRAPEIISGEVSLSESFAXXXXXXXXXXXXXXLDVNHMDLVTKKRLTRAVDIFS 943
T +RAPE+ L+ T A+DI+S
Sbjct: 193 YVVTRWYRAPEL---------------------------------LLNSSEYTGAIDIWS 219
Query: 944 LGCIFYYVLSKGE-HPFGDRI--------------------LREANILKGDYRLDGI-KK 981
+GCIF +L + P D + LR N K +L + K+
Sbjct: 220 VGCIFMEILRRETLFPGKDYVQQLKLITELLGSPDDSDLDFLRSDNARKYVKQLPHVQKQ 279
Query: 982 SIQER--SVCIEAADLIKSMLEQNPLLRPASDEILKHP 1017
S +E+ ++ A DL + ML +P R DE LK P
Sbjct: 280 SFREKFPNISPMALDLAEKMLVFDPSKRITVDEALKQP 317
>7293761 [T] KOG4721 Serine/threonine protein kinase contains leucine zipper
domain
Length = 977
Score = 63.5 bits (153), Expect = 2e-09
Identities = 59/186 (31%), Positives = 92/186 (48%), Gaps = 32/186 (17%)
Query: 715 LGYGSSGTVVFQGKFQNRPVAVKRLLIDFYDIASKEIQLLSESDDHPNVIRYYFSESTEK 774
LG G+ G V F G+ +N VAVK++ ++ +I+ L + D H N+I++ +
Sbjct: 167 LGSGAQGAV-FSGRLKNETVAVKKVK----ELKETDIKHLRKLD-HENIIKFKGVCTQSP 220
Query: 775 FMYIAVELCS-ASLEDVIEGSKGLAKNVAVQKNIDPINVLFQITSGVNHLHSMKIVHRDL 833
I +E C L+++++ + + + V + QI G+ +LHS KI+HRDL
Sbjct: 221 VFCIIMEFCPYGPLQNILKEEQVMLPSRLVSWSK-------QIALGMQYLHSHKIIHRDL 273
Query: 834 KPQNILIAPPKRYLSLHASKNKFRVLISDFGLCKKLEIDESSFRTNNFNNPTGTSGWRAP 893
K NILI S N+ V ISDFG + E +E S + + GT W AP
Sbjct: 274 KSPNILI-----------STNEV-VKISDFGTSR--EWNEISTKMSF----AGTVAWMAP 315
Query: 894 EIISGE 899
E+I E
Sbjct: 316 EVIRNE 321
>YNL307c [G] KOG0658 Glycogen synthase kinase-3
Length = 375
Score = 63.2 bits (152), Expect = 2e-09
Identities = 57/198 (28%), Positives = 102/198 (50%), Gaps = 35/198 (17%)
Query: 713 RVLGYGSSGTVVFQGKFQNR-----PVAVKRLLIDFYDIASKEIQLLSESDDHPNVIR-- 765
R +G G+ GTVV Q++ P A+K++ + S+E+Q+L +D HPN+++
Sbjct: 39 RKIGRGAFGTVVQAYLTQDKKNWLGPFAIKKVPAHT-EYKSRELQILRIAD-HPNIVKLQ 96
Query: 766 YYFS----ESTEKFMYIAVELCSASLEDVIEGSKGLAKNVAVQ-KNIDPINVLFQITSGV 820
Y+F+ + + + ++A+E +L+ IE ++ + + + K+I +QI G+
Sbjct: 97 YFFTHLSPQDNKVYQHLAMECLPETLQ--IEINRYVTNKLEMPLKHIRLYT--YQIARGM 152
Query: 821 NHLHSMKIVHRDLKPQNILIAPPKRYLSLHASKNKFRVLISDFGLCKKLEIDESSFRTNN 880
+LH + + HRD+KP N+L+ P L I DFG KKLE ++ S
Sbjct: 153 LYLHGLGVCHRDIKPSNVLVDPETGVLK-----------ICDFGSAKKLEHNQPSI---- 197
Query: 881 FNNPTGTSGWRAPEIISG 898
+ + +RAPE+I G
Sbjct: 198 --SYICSRFYRAPELIIG 213
>HsM4504163 [G] KOG0658 Glycogen synthase kinase-3
Length = 420
Score = 63.2 bits (152), Expect = 2e-09
Identities = 61/204 (29%), Positives = 101/204 (48%), Gaps = 35/204 (17%)
Query: 712 SRVLGYGSSGTVVFQGKF--QNRPVAVKRLLIDFYDIASKEIQLLSESDDHPNVIR--YY 767
++V+G GS G VV+Q K VA+K++L D ++E+Q++ + D H N++R Y+
Sbjct: 59 TKVIGNGSFG-VVYQAKLCDSGELVAIKKVLQD-KRFKNRELQIMRKLD-HCNIVRLRYF 115
Query: 768 FSESTEKFMYIAVELCSASLEDVIEGSKGLAKNVAVQKNIDPINV----LFQITSGVNHL 823
F S EK + + L L+ V E +A++ + K P+ ++Q+ + ++
Sbjct: 116 FYSSGEKKDEVYLNLV---LDYVPETVYRVARHYSRAKQTLPVIYVKLYMYQLFRSLAYI 172
Query: 824 HSMKIVHRDLKPQNILIAPPKRYLSLHASKNKFRVLISDFGLCKKLEIDES--SFRTNNF 881
HS I HRD+KPQN+L+ P L L DFG K+L E S+ + +
Sbjct: 173 HSFGICHRDIKPQNLLLDPDTAVLKL-----------CDFGSAKQLVRGEPNVSYICSRY 221
Query: 882 NNPTGTSGWRAPEIISGEVSLSES 905
+RAPE+I G + S
Sbjct: 222 --------YRAPELIFGATDYTSS 237
>Hs21361340 [G] KOG0658 Glycogen synthase kinase-3
Length = 433
Score = 63.2 bits (152), Expect = 2e-09
Identities = 61/204 (29%), Positives = 101/204 (48%), Gaps = 35/204 (17%)
Query: 712 SRVLGYGSSGTVVFQGKF--QNRPVAVKRLLIDFYDIASKEIQLLSESDDHPNVIR--YY 767
++V+G GS G VV+Q K VA+K++L D ++E+Q++ + D H N++R Y+
Sbjct: 59 TKVIGNGSFG-VVYQAKLCDSGELVAIKKVLQD-KRFKNRELQIMRKLD-HCNIVRLRYF 115
Query: 768 FSESTEKFMYIAVELCSASLEDVIEGSKGLAKNVAVQKNIDPINV----LFQITSGVNHL 823
F S EK + + L L+ V E +A++ + K P+ ++Q+ + ++
Sbjct: 116 FYSSGEKKDEVYLNLV---LDYVPETVYRVARHYSRAKQTLPVIYVKLYMYQLFRSLAYI 172
Query: 824 HSMKIVHRDLKPQNILIAPPKRYLSLHASKNKFRVLISDFGLCKKLEIDES--SFRTNNF 881
HS I HRD+KPQN+L+ P L L DFG K+L E S+ + +
Sbjct: 173 HSFGICHRDIKPQNLLLDPDTAVLKL-----------CDFGSAKQLVRGEPNVSYICSRY 221
Query: 882 NNPTGTSGWRAPEIISGEVSLSES 905
+RAPE+I G + S
Sbjct: 222 --------YRAPELIFGATDYTSS 237
>Hs20545245 [D] KOG0588 Serine/threonine protein kinase
Length = 795
Score = 63.2 bits (152), Expect = 2e-09
Identities = 71/290 (24%), Positives = 119/290 (40%), Gaps = 70/290 (24%)
Query: 759 DHPNVIRYYFSESTEKFMYIAVELCSAS-LEDVIEGSKGLAKNVAVQKNIDPINVLFQIT 817
+HP+V++ + +K++Y+ +E S L D + L A + QI
Sbjct: 106 EHPHVLKLHDVYENKKYLYLVLEHVSGGELFDYLVKKGRLTPKEARK-------FFRQIV 158
Query: 818 SGVNHLHSMKIVHRDLKPQNILIAPPKRYLSLHASKNKFRVLISDFGLCKKLEIDESSFR 877
S ++ HS I HRDLKP+N+L+ KN R I+DFG+ L++ +S
Sbjct: 159 SALDFCHSYSICHRDLKPENLLL----------DEKNNIR--IADFGMA-SLQVGDSLLE 205
Query: 878 TNNFNNPTGTSGWRAPEIISGEVSLSESFAXXXXXXXXXXXXXXLDVNHMDLVTKKRLTR 937
T+ G+ + PE+I GE K R
Sbjct: 206 TS-----CGSPHYACPEVIKGE---------------------------------KYDGR 227
Query: 938 AVDIFSLGCIFYYVLSKGEHPFGDRILREANILKGDYRLDGIKKSI--QERSVCIEAADL 995
D++S G I + +L G PF D LR+ L+ +K+ + + + L
Sbjct: 228 RADMWSCGVILFALL-VGALPFDDDNLRQL--------LEKVKRGVFHMPHFIPPDCQSL 278
Query: 996 IKSMLEQNPLLRPASDEILKHPLFWGVSKKLEFLLKVSDRFEVERRDPPS 1045
++ M+E P R + ++I KHP + G + + L+ + V R PS
Sbjct: 279 LRGMIEVEPEKRLSLEQIQKHPWYLGGKHEPDPCLEPAPGRRVAMRSLPS 328
>ECU02g0550 [D] KOG0575 Polo-like serine/threonine protein kinase
Length = 516
Score = 63.2 bits (152), Expect = 2e-09
Identities = 74/309 (23%), Positives = 125/309 (39%), Gaps = 88/309 (28%)
Query: 713 RVLGYGSSGTVVFQGKFQNRPVAVKRLLIDFYD--IASKEIQLLSESDDHPNVIRYYFSE 770
+V+G G+S TV + VAVK + + +EI++LS + H N++
Sbjct: 8 QVIGEGASSTVYSGVSARGEEVAVKVVPRKGRSTGMVYREIEMLS-TIKHENIVGIVGRF 66
Query: 771 STEKFMYIAVELCSASLEDVIEGSKGLAKNVAVQKNIDPINVLFQITSGVNHLHSMKIVH 830
++K +Y+ ELC +L + + + ++VA++ +L I G+ H+HS+ I+H
Sbjct: 67 ESKKHVYMVEELCDFNLVSFLNEYE-VDEDVALK-------ILRMILCGLRHIHSLGIIH 118
Query: 831 RDLKPQNILIAPPKRYLSLHASKNKFRVLISDFGLCKKLEIDESSFRTNNFNNPTGTSGW 890
RDLK NIL+ V I DFGL +E + S F GT +
Sbjct: 119 RDLKLGNILL-------------KGNTVKICDFGLSCYVEENNSEF--------CGTMDY 157
Query: 891 RAPEIISGEVSLSESFAXXXXXXXXXXXXXXLDVNHMDLVTKKRLTRAVDIFSLGCIFYY 950
APE++ G K+ + VD++S G +FY
Sbjct: 158 LAPEVVDG----------------------------------KKYSFGVDMWSAGVVFYV 183
Query: 951 VLSKGEHPFGDRILREANILKGDYRLDGIKKSIQERSVCIEAADLIKSMLEQNPLLRPAS 1010
+L+K + +S+ E DL++ +LE++ R +
Sbjct: 184 LLTKKK----------------------FCESLDSLECSEELRDLLEKLLERDESKRADA 221
Query: 1011 DEILKHPLF 1019
E L H F
Sbjct: 222 SEALMHRSF 230
>CE18454 [T] KOG4717 Serine/threonine protein kinase
Length = 1016
Score = 63.2 bits (152), Expect = 2e-09
Identities = 75/292 (25%), Positives = 125/292 (42%), Gaps = 71/292 (24%)
Query: 729 FQNRPVAVKRLLIDFYDIAS-----KEIQLLSESDDHPNVIRYYFSESTEKFMYIAVELC 783
F VAVK + D AS KE++ + + H N++R Y T+ +++ +EL
Sbjct: 48 FTGEMVAVKIIDKTKMDEASTSQIMKEVRCM-KLVQHANIVRLYEVLDTQTKIFLILELG 106
Query: 784 SASLED-VIEGSKGLAKNVAVQKNIDPINVLFQITSGVNHLHSMKIVHRDLKPQNILIAP 842
L D +I+ KG+ +++A Q QI + +++ H + +VHRDLKP+N++
Sbjct: 107 DYDLHDFIIKHEKGVCESLAQQ-------YFCQIMTAIDYCHQLHVVHRDLKPENVVF-- 157
Query: 843 PKRYLSLHASKNKFRVLISDFGLCKKLEIDESSFRTNNFNNPTGTSGWRAPEIISGEVSL 902
+ V ++DFG E E N G+ + APEI+ G+
Sbjct: 158 ---------FEKLGMVKLTDFGFSNSYEPGE------QLNTSCGSLAYSAPEILLGD--- 199
Query: 903 SESFAXXXXXXXXXXXXXXLDVNHMDLVTKKRLTRAVDIFSLGCIFYYVLSKGEHPFGDR 962
AVD++SLG I Y+L G PF
Sbjct: 200 ------------------------------SYDAPAVDVWSLGVIL-YMLVCGRLPF--- 225
Query: 963 ILREANILKGDYRLDGIKKSIQERSVCIEAADLIKSMLEQNPLLRPASDEIL 1014
+EAN + ++ K SI + + E +LI+SML + P R + ++I+
Sbjct: 226 --QEANDSETLTKILDCKYSIPD-VLSDECRNLIQSMLVREPQKRASLEKIV 274
>CE07285 [D] KOG0575 Polo-like serine/threonine protein kinase
Length = 615
Score = 63.2 bits (152), Expect = 2e-09
Identities = 68/263 (25%), Positives = 109/263 (40%), Gaps = 71/263 (26%)
Query: 760 HPNVIRYYFSESTEKFMYIAVELCSA-SLEDVIEGSKGLAKNVAVQKNIDPINVLFQITS 818
H N+++++ + +Y +ELCS SL ++ + L ++ A I Q+
Sbjct: 92 HRNIVQFHHFFEDSQNVYFTLELCSKNSLMELNKQRGPLTEHEARFYTI-------QVAE 144
Query: 819 GVNHLHSMKIVHRDLKPQNILIAPPKRYLSLHASKNKFRVLISDFGLCKKLEIDESSFRT 878
GV HLH+++I+HRDLK N+ +L+ H +V I DFGL E +E
Sbjct: 145 GVKHLHNLQIIHRDLKLGNL-------FLNEH-----LQVKIGDFGLATFCEKNEKKMTR 192
Query: 879 NNFNNPTGTSGWRAPEIISGEVSLSESFAXXXXXXXXXXXXXXLDVNHMDLVTKKRLTRA 938
GT + APE+++ + H
Sbjct: 193 G------GTPNYIAPEVLN-------------------------ETGH---------AFE 212
Query: 939 VDIFSLGCIFYYVLSKGEHPFGDRILRE--ANILKGDYRLDGIKKSIQERSVCIEAADLI 996
VDI+++GCI YVL G PF R ++E I DY + + A LI
Sbjct: 213 VDIWAIGCIL-YVLLFGSPPFESRRVQETYVRIKNNDY--------VVPENASPTANRLI 263
Query: 997 KSMLEQNPLLRPASDEILKHPLF 1019
+S+L+ P RP ++ +L F
Sbjct: 264 RSLLDPVPDRRPTAEAVLLDQFF 286
>At5g04510 [T] KOG0592 3-phosphoinositide-dependent protein kinase (PDK1)
Length = 488
Score = 63.2 bits (152), Expect = 2e-09
Identities = 82/343 (23%), Positives = 142/343 (40%), Gaps = 79/343 (23%)
Query: 701 QEGHLKHLSISSRVLGYGSSGTVVFQGKFQNRPV-AVKRLLIDFYDIASKEI-----QLL 754
QE H ++ G GS VV K + V A+K + F +K +++
Sbjct: 33 QENFTSHDFEFGKIYGVGSYSKVVRAKKKETGTVYALKIMDKKFITKENKTAYVKLERIV 92
Query: 755 SESDDHPNVIRYYFSESTEKFMYIAVELCSAS-LEDVIEGSKGLAKNVAVQKNIDPINVL 813
+ +HP +I+ YF+ +Y+A+E C L D I L+++ A + ++ L
Sbjct: 93 LDQLEHPGIIKLYFTFQDTSSLYMALESCEGGELFDQITRKGRLSEDEARFYTAEVVDAL 152
Query: 814 FQITSGVNHLHSMKIVHRDLKPQNILIAPPKRYLSLHASKNKFRVLISDFGLCKKLEIDE 873
++HSM ++HRD+KP+N+L+ + + I+DFG K ++ +
Sbjct: 153 -------EYIHSMGLIHRDIKPENLLLT------------SDGHIKIADFGSVKPMQDSQ 193
Query: 874 SSFRTNNFNNP-----TGTSGWRAPEIISGEVSLSESFAXXXXXXXXXXXXXXLDVNHMD 928
+ N ++ GT+ + PE+++ +
Sbjct: 194 ITVLPNAASDDKACTFVGTAAYVPPEVLNSSPA--------------------------- 226
Query: 929 LVTKKRLTRAVDIFSLGCIFYYVLSKGEHPFGDRILREANILKGDYRLDGIKKSIQERSV 988
T D+++LGC Y +LS G PF D E I + R+ I + I+ +
Sbjct: 227 -------TFGNDLWALGCTLYQMLS-GTSPFKD--ASEWLIFQ---RI--IARDIKFPNH 271
Query: 989 CIEAA-DLIKSMLEQNPLLRPASDE-----ILKHPLFWGVSKK 1025
EAA DLI +L+ P RP + + +HP F GV K
Sbjct: 272 FSEAARDLIDRLLDTEPSRRPGAGSEGYVALKRHPFFNGVDWK 314
>At3g61160 [G] KOG0658 Glycogen synthase kinase-3
Length = 431
Score = 63.2 bits (152), Expect = 2e-09
Identities = 86/339 (25%), Positives = 135/339 (39%), Gaps = 86/339 (25%)
Query: 711 SSRVLGYGSSGTVVFQGKF--QNRPVAVKRLLIDFYDIASKEIQLLSESDDHPNVI--RY 766
+ V+G GS G VVFQ K VA+K++L D ++E+Q++ D HPNV+ ++
Sbjct: 104 AEHVIGTGSFG-VVFQAKCLETEEKVAIKKVLQD-KRYKNRELQIMRMLD-HPNVVELKH 160
Query: 767 YFSESTEK---FMYIAVELCSASLEDVIEGSKGLAKNVAVQKNIDPINVLFQITSGVNHL 823
F +TEK ++ + +E E + S+ K I +QI +N+L
Sbjct: 161 SFFSTTEKDELYLNLVLEYVP---ETIYRASRSYTKMNQHMPLIYIQLYTYQICRAMNYL 217
Query: 824 HSMK-IVHRDLKPQNILIAPPKRYLSLHASKNKFRVLISDFGLCKKLEIDESSFRTNNFN 882
H + + HRD+KPQN+L+ + V I DFG K L E +
Sbjct: 218 HQVVGVCHRDIKPQNLLV-----------NNVTHEVKICDFGSAKMLIPGEPNI------ 260
Query: 883 NPTGTSGWRAPEIISGEVSLSESFAXXXXXXXXXXXXXXLDVNHMDLVTKKRLTRAVDIF 942
+ + +RAPE+I G T A+D++
Sbjct: 261 SYICSRYYRAPELIFGAT---------------------------------EYTSAIDMW 287
Query: 943 SLGCIFY-----YVLSKGEHPFGDRI-------------LREANILKGDYRLDGIK---- 980
S+GC+ + L GE + ++ N D++ IK
Sbjct: 288 SVGCVMAELFLGHPLFPGETSVDQLVEIIKILGTPAREEIKNMNPRYNDFKFPQIKAQPW 347
Query: 981 KSIQERSVCIEAADLIKSMLEQNPLLRPASDEILKHPLF 1019
I R V EA DL +L+ +P LR + E HP F
Sbjct: 348 HKIFRRQVSPEAMDLASRLLQYSPNLRCTALEACAHPFF 386
>7300224 [T] KOG0201 Serine/threonine protein kinase
Length = 642
Score = 63.2 bits (152), Expect = 2e-09
Identities = 83/331 (25%), Positives = 140/331 (42%), Gaps = 77/331 (23%)
Query: 715 LGYGSSGTVVFQGKFQNRPVAVKRLLI-------DFYDIASKEIQLLSESDDHPNVIRYY 767
+G GS G V F+G NR V + I D D +EI +LS+ D P V +YY
Sbjct: 19 IGKGSFGEV-FKG-IDNRTQQVVAIKIIDLEEAEDEIDDIQQEIMVLSQCDS-PYVTKYY 75
Query: 768 FSESTEKFMYIAVE-LCSASLEDVIEGSKGLAKNVAVQKNIDPINVLFQITSGVNHLHSM 826
S ++I +E L S D+++ ++ + +L ++ G+++LHS
Sbjct: 76 GSFLKGTKLWIIMEYLGGGSALDLMKAGSFEEMHIGI--------ILREVLKGLDYLHSE 127
Query: 827 KIVHRDLKPQNILIAPPKRYLSLHASKNKFRVLISDFGLCKKLEIDESSFRTNNFNNPTG 886
+ +HRD+K N+L++ + V ++DFG+ +L + T+ N G
Sbjct: 128 RKLHRDIKAANVLLS------------EQGDVKLADFGVAGQL-----TNTTSKRNTFVG 170
Query: 887 TSGWRAPEIISGEVSLSESFAXXXXXXXXXXXXXXLDVNHMDLVTKKRLTRAVDIFSLGC 946
T W APE+I + + DI+SLG
Sbjct: 171 TPFWMAPEVIK----------------------------------QSQYDAKADIWSLG- 195
Query: 947 IFYYVLSKGEHPFGDRILREANILKGDYRLDGIKKSIQERSVCIEAADLIKSMLEQNPLL 1006
I L+KGE P + L +L + + S D +++ L ++P
Sbjct: 196 ITAIELAKGEPPNSE--LHPMRVL---FLIPKNNPPQLTGSYTKSFKDFVEACLNKDPEN 250
Query: 1007 RPASDEILKHPLFWGVSKKLEFLLKVSDRFE 1037
RP + E+LK+P F +KK +L+ + DRF+
Sbjct: 251 RPTAKELLKYP-FIKKAKKNAYLIDLIDRFK 280
>SPBC21.06c [T] KOG0198 MEKK and related serine/threonine protein kinases
Length = 1062
Score = 62.8 bits (151), Expect = 3e-09
Identities = 72/310 (23%), Positives = 125/310 (40%), Gaps = 74/310 (23%)
Query: 715 LGYGSSGTVVFQGKFQN------RPVAVKRLLIDFYDIASKEIQLLSESDDHPNVIRYYF 768
LG G+ G V +N + V + ++L + EI LL D HPN+++Y
Sbjct: 15 LGKGAFGAVYRGLNIKNGETVAVKKVKLSKMLKSDLSVIKMEIDLLKNLD-HPNIVKYRG 73
Query: 769 SESTEKFMYIAVELC-SASLEDVIEGSKGLAKNVAVQKNIDPINVLFQITSGVNHLHSMK 827
S T + I +E C + SL + + + +N+ FQ+ G+ +LH+
Sbjct: 74 SYQTNDSLCIILEYCENGSLRSICKNFGKIPENLVALYT-------FQVLQGLLYLHNQG 126
Query: 828 IVHRDLKPQNILIAPPKRYLSLHASKNKFRVLISDFGLCKKLEIDESSFRTNNFNNPTGT 887
++HRD+K NIL + + ++DFG+ K+ E ++ G+
Sbjct: 127 VIHRDIKGANIL------------TTKDGTIKLADFGVATKINALED-------HSVVGS 167
Query: 888 SGWRAPEIISGEVSLSESFAXXXXXXXXXXXXXXLDVNHMDLVTKKRLTRAVDIFSLGCI 947
W APE+I +LV T A DI+S+GC
Sbjct: 168 PYWMAPEVI-------------------------------ELV---GATTASDIWSVGCT 193
Query: 948 FYYVLSKGEHPFGDRILREANILKGDYRLDGIKKSIQERSVCIEAADLIKSMLEQNPLLR 1007
+L G P+ D L + L +R+ + ++ A + +++P LR
Sbjct: 194 VIELLD-GNPPYYD--LDPTSAL---FRMVKDEHPPLPSNISSAAKSFLMQCFQKDPNLR 247
Query: 1008 PASDEILKHP 1017
+ ++LKHP
Sbjct: 248 IKTRKLLKHP 257
>Hs4557511 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-Hand protein
superfamily
Length = 454
Score = 62.8 bits (151), Expect = 3e-09
Identities = 73/271 (26%), Positives = 114/271 (41%), Gaps = 64/271 (23%)
Query: 749 KEIQLLSESDDHPNVIRYYFSESTEKFMYIAVELCSAS-LEDVIEGSKGLAKNVAVQKNI 807
+E+ +L E HPN+I + + + + +EL S L D + + L ++ A Q
Sbjct: 63 REVNILREIR-HPNIITLHDIFENKTDVVLILELVSGGELFDFLAEKESLTEDEATQ--- 118
Query: 808 DPINVLFQITSGVNHLHSMKIVHRDLKPQNILIAPPKRYLSLHASKNKFRVLISDFGLCK 867
L QI GV++LHS +I H DLKP+NI++ L + R+ + DFG+
Sbjct: 119 ----FLKQILDGVHYLHSKRIAHFDLKPENIML--------LDKNVPNPRIKLIDFGIAH 166
Query: 868 KLEIDESSFRTNNFNNPTGTSGWRAPEIISGEVSLSESFAXXXXXXXXXXXXXXLDVNHM 927
K+E N F N GT + APEI++ E
Sbjct: 167 KIEAG------NEFKNIFGTPEFVAPEIVNYE---------------------------- 192
Query: 928 DLVTKKRLTRAVDIFSLGCIFYYVLSKGEHPFGDRILRE--ANILKGDYRLDGIKKSIQE 985
L D++S+G I Y +LS G PF +E NI +Y D ++
Sbjct: 193 ------PLGLEADMWSIGVITYILLS-GASPFLGETKQETLTNISAVNYDFD--EEYFSN 243
Query: 986 RSVCIEAADLIKSMLEQNPLLRPASDEILKH 1016
S A D I+ +L ++P R + L+H
Sbjct: 244 TSEL--AKDFIRRLLVKDPKRRMTIAQSLEH 272
>Hs4506103 [J] KOG1033 eIF-2alpha kinase PEK/EIF2AK3
Length = 551
Score = 62.8 bits (151), Expect = 3e-09
Identities = 73/268 (27%), Positives = 112/268 (41%), Gaps = 73/268 (27%)
Query: 756 ESDDHPNVIRYYFSESTEKFMYIAVELCS-ASLEDVIEGSKG--LAKNVAVQKNIDPINV 812
ES D+ S S K ++I +E C +LE IE +G L K +A++ +
Sbjct: 342 ESSDYDPENSKNSSRSKTKCLFIQMEFCDKGTLEQWIEKRRGEKLDKVLALE-------L 394
Query: 813 LFQITSGVNHLHSMKIVHRDLKPQNILIAPPKRYLSLHASKNKFRVLISDFGLCKKLEID 872
QIT GV+++HS K++HRDLKP NI + K +V I DFGL L+ D
Sbjct: 395 FEQITKGVDYIHSKKLIHRDLKPSNIFLVDTK------------QVKIGDFGLVTSLKND 442
Query: 873 ESSFRTNNFNNPTGTSGWRAPEIISGEVSLSESFAXXXXXXXXXXXXXXLDVNHMDLVTK 932
R+ GT + +PE IS S+ +
Sbjct: 443 GKRTRSK------GTLRYMSPEQIS-----SQDYG------------------------- 466
Query: 933 KRLTRAVDIFSLGCIFYYVLSKGEHPFGDRILREANILKGDYRLDGIKKSIQERSVCIEA 992
+ VD+++LG I +L + F E + D R DGI I ++ +
Sbjct: 467 ----KEVDLYALGLILAELLHVCDTAF------ETSKFFTDLR-DGIISDIFDK----KE 511
Query: 993 ADLIKSMLEQNPLLRPASDEILKHPLFW 1020
L++ +L + P RP + EIL+ W
Sbjct: 512 KTLLQKLLSKKPEDRPNTSEILRTLTVW 539
>CE25060 [T] KOG0196 Tyrosine kinase EPH (ephrin) receptor family
Length = 1117
Score = 62.8 bits (151), Expect = 3e-09
Identities = 68/266 (25%), Positives = 109/266 (40%), Gaps = 72/266 (27%)
Query: 709 SISSRVLGYGSSGTVVFQGKFQNRP---VAVKRLLIDFYDIASKEIQLLSESD-----DH 760
S+S+ +G G G G +++ P VA+K L A + + L+E+ H
Sbjct: 722 SVSNTTMGRGGGG-----GGYESEPYETVAIKTLKSG--SSAKAKAEFLTEATIMGQFSH 774
Query: 761 PNVIRYY-FSESTEKFMYIAVELCSASLEDVIEGSKGLAKNVAVQKNIDPINVLFQITSG 819
PNVIR S E M +A + + SL+ + + + V +K + +L+ I SG
Sbjct: 775 PNVIRLIGVVTSAEPVMIVAEYMANGSLDQFLRNTDQRGEKVHWEKITE---MLYGIASG 831
Query: 820 VNHLHSMKIVHRDLKPQNILIAPPKRYLSLHASKNKFRVLISDFGLCKKLEIDESS---- 875
+ +L M VHRDL +N+L+ + R I+DFGL + + + SS
Sbjct: 832 MKYLTDMGYVHRDLAARNVLL------------DMELRCKIADFGLSRGVRSEGSSVEPE 879
Query: 876 FRTNNFNNPTGTSGWRAPEIISGEVSLSESFAXXXXXXXXXXXXXXLDVNHMDLVTKKRL 935
+ TN P W APE I T ++
Sbjct: 880 YTTNGGKIPV---RWTAPEAI----------------------------------THRKF 902
Query: 936 TRAVDIFSLGCIFYYVLSKGEHPFGD 961
T + D++S G + + V S GE P+ D
Sbjct: 903 TPSSDVWSFGVVIWEVCSFGERPYWD 928
>CE09940 [D] KOG0601 Cyclin-dependent kinase WEE1
Length = 468
Score = 62.8 bits (151), Expect = 3e-09
Identities = 52/213 (24%), Positives = 92/213 (42%), Gaps = 29/213 (13%)
Query: 696 FKEFEQEGHLKHLSISSRVLGYGSSGTVVF------QGKFQNRPVAVKRLLIDFYDIASK 749
+K + + H + LG GS G VV KF + + +L D Y A
Sbjct: 93 YKRSKSDSFFDHAFNFDKNLGKGSFGEVVAATCRSTSKKFAIKKIPFSKLSKDQYREAYG 152
Query: 750 EIQLLSESDDHPNVIRYYFSESTEKFMYIAVELCSASLEDVIEGSKGLAKNVAVQKNIDP 809
+ + HPN++R++ + ++ ++I +E+C SL G L ++ +
Sbjct: 153 HMNIPC----HPNIVRFHQAWIDKQILHIQLEMCDKSLAAYCHGIDWL-------EDKEL 201
Query: 810 INVLFQITSGVNHLHSMKIVHRDLKPQNILIAPPKRYLSLHASKNKFRVLISDFGLCKKL 869
NV I G+ HLH+ ++H D+KP NI + +KNK + DFGL +
Sbjct: 202 WNVFLDILQGLGHLHNNFMLHNDIKPDNIFM-----------TKNKV-CKLGDFGLISDM 249
Query: 870 EIDESSFRTNNFNNPTGTSGWRAPEIISGEVSL 902
+ + +N G + + E I+G +S+
Sbjct: 250 RSEPINNSSNKHYQSEGDGKYCSKEAINGTLSI 282
>At5g63610 [K] KOG0666 Cyclin C-dependent kinase CDK8
Length = 470
Score = 62.8 bits (151), Expect = 3e-09
Identities = 85/355 (23%), Positives = 143/355 (39%), Gaps = 102/355 (28%)
Query: 715 LGYGSSGTVVFQGKFQN---RPVAVKRLLID-----FYDIASKEIQLLSESDDHPNVIRY 766
+G G+ G +VF + + RP+A+K+ A +EI LL E H NV++
Sbjct: 31 IGEGTYG-LVFLARTKTPPKRPIAIKKFKQSKDGDGVSPTAIREIMLLREIS-HENVVKL 88
Query: 767 Y--FSESTEKFMYIAVELCSASLEDVIEGSK---GLAKNVAVQKNIDPINVLFQITSGVN 821
+ +Y+A + L ++I + G + N K++ L+Q+ +G+N
Sbjct: 89 VNVHINFADMSLYLAFDYAEYDLYEIIRHHRDKVGHSLNTYTVKSL-----LWQLLNGLN 143
Query: 822 HLHSMKIVHRDLKPQNILIAPPKRYLSLHASKNKFRVLISDFGLCKKLEIDESSFRTNNF 881
+LHS I+HRDLKP NIL+ + ++ V I+DFGL + I ++ + +
Sbjct: 144 YLHSNWIIHRDLKPSNILV--------MGDAEEHGIVKIADFGLAR---IYQAPLKPLSD 192
Query: 882 NNPTGTSGWRAPEIISGEVSLSESFAXXXXXXXXXXXXXXLDVNHMDLVTKKRLTRAVDI 941
N T +RAPE++ G K T AVD+
Sbjct: 193 NGVVVTIWYRAPELLLG---------------------------------SKHYTSAVDM 219
Query: 942 FSLGCIFYYVLS-----------KGEHPFG----DRILR--------------------- 965
+++GCIF +L+ ++PF D+I +
Sbjct: 220 WAVGCIFAELLTLKPLFQGAEAKSSQNPFQLDQLDKIFKILGHPTMDKWPTLVNLPHWQN 279
Query: 966 -EANILKGDYRLDGIKKSIQERSVCIEAADLIKSMLEQNPLLRPASDEILKHPLF 1019
+I Y G+ + A DL+ MLE +PL R + + L+H F
Sbjct: 280 DVQHIQAHKYDSVGLHNVVHLNQKS-PAYDLLSKMLEYDPLKRITASQALEHEYF 333
>At2g42630 [T] KOG0192 Tyrosine kinase specific for activated (GTP-bound)
p21cdc42Hs
Length = 357
Score = 62.8 bits (151), Expect = 3e-09
Identities = 65/214 (30%), Positives = 98/214 (45%), Gaps = 35/214 (16%)
Query: 692 PMLDFKEFEQEGHLKHLSISSRVLGYGSSGTVVFQGKFQNRPVAVK-----RLLIDFYDI 746
P+L F+E+ + L + + V G G+SG VV +G + VA+K +L + +
Sbjct: 90 PLLPFEEWNID--FSKLKVGASV-GSGTSG-VVCRGVWNKTEVAIKIFLGQQLTAENMKV 145
Query: 747 ASKEIQLLSESDDHPNVIRYYFSESTEKFMYIAVELCSA-SLEDVIEGSKGLAKNVAVQK 805
EI +LS HPNVI + + + + E S SL DVI K K ++ Q+
Sbjct: 146 FCNEISILSRLQ-HPNVILLLGACTKPPQLSLVTEYMSTGSLYDVIRTRK---KELSWQR 201
Query: 806 NIDPINVLFQITSGVNHLHSMKIVHRDLKPQNILIAPPKRYLSLHASKNKFRVLISDFGL 865
+ +L +I G+ ++H M IVHRDL N L+ NK V I DFGL
Sbjct: 202 KL---KILAEICRGLMYIHKMGIVHRDLTSANCLL-------------NKSIVKICDFGL 245
Query: 866 CKKLEIDESSFRTNNFNNPTGTSGWRAPEIISGE 899
+++ + GT W APE+I E
Sbjct: 246 SRRM-----TGTAVKDTEAAGTPEWMAPELIRNE 274
>7290150 [T] KOG0583 Serine/threonine protein kinase
Length = 582
Score = 62.8 bits (151), Expect = 3e-09
Identities = 87/315 (27%), Positives = 129/315 (40%), Gaps = 78/315 (24%)
Query: 715 LGYGSSGTV-VFQGKFQNRPVAVK---RLLIDFYDIASK---EIQLLSESDDHPNVIRYY 767
LG G+ G V + + + VAVK R I D+ K EIQ L + HP++I+ Y
Sbjct: 34 LGTGTFGKVKIGEHQITRVKVAVKILNRQKIKSLDVVGKIRREIQNL-KLFRHPHIIKLY 92
Query: 768 FSESTEKFMYIAVELCSAS-LEDVIEGSKGLAKNVAVQKNIDPINVLFQITSGVNHLHSM 826
ST +++ +E S L D I L ++ A + QI SGV++ H
Sbjct: 93 QVISTPSDIFMIMEYVSGGELFDYIVKHGKLQEHQARR-------FFQQIISGVDYCHRH 145
Query: 827 KIVHRDLKPQNILIAPPKRYLSLHASKNKFRVLISDFGLCKKLEIDESSFRTNNFNNPTG 886
IVHRDLKP+N+L+ + V I+DFGL + +D RT+ G
Sbjct: 146 MIVHRDLKPENLLL------------DHNMHVKIADFGL-SNMMLDGEFLRTS-----CG 187
Query: 887 TSGWRAPEIISGEVSLSESFAXXXXXXXXXXXXXXLDVNHMDLVTKKRLTRAVDIFSLGC 946
+ + APE+ISG++ VDI+S G
Sbjct: 188 SPNYAAPEVISGKLYAGPE---------------------------------VDIWSCGV 214
Query: 947 IFYYVLSKGEHPFGDRILRE--ANILKGDYRLDGIKKSIQERSVCIEAADLIKSMLEQNP 1004
I Y +L G PF D + I G + + + +L+ ML+ +P
Sbjct: 215 ILYALLC-GTLPFDDEHVPTLFRKIKSGIFPIPEYLNK--------QVVNLVCQMLQVDP 265
Query: 1005 LLRPASDEILKHPLF 1019
L R +EI KH F
Sbjct: 266 LKRANIEEIKKHEWF 280
>SPACUNK12.02c [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-Hand protein
superfamily
Length = 335
Score = 62.4 bits (150), Expect = 4e-09
Identities = 85/317 (26%), Positives = 125/317 (38%), Gaps = 74/317 (23%)
Query: 713 RVLGYGSSGTV-----VFQGKFQNRPVAVKRLLIDFYDIASKEIQLLSE-SDDHPNVIRY 766
RVLG G+ TV + K + K+++ D EI +L S +HPN++
Sbjct: 35 RVLGGGTYATVREAVHIETNKMYAAKIMNKKMMEKKQDFVKNEIAILKRVSYEHPNILHL 94
Query: 767 YFSESTEKFMYIAVELCSAS-LEDVI--EGSKGLAKNVAVQKNIDPINVLFQITSGVNHL 823
T +Y+ EL + L D I +GS A A+ + TS V +L
Sbjct: 95 VDFFETVNNLYLITELATGGELFDRICAKGSFYEADAAALMRTT---------TSAVKYL 145
Query: 824 HSMKIVHRDLKPQNILIAPPKRYLSLHASKNKFRVLISDFGLCKKLEIDESSFRTNNFNN 883
H IVHRDLKP+N+L Y S + + +LI+DFGL E +
Sbjct: 146 HDNGIVHRDLKPENLL------YRSKDPNSD---LLIADFGLSHFYEDSQYYM----LMT 192
Query: 884 PTGTSGWRAPEIISGEVSLSESFAXXXXXXXXXXXXXXLDVNHMDLVTKKRLTRAVDIFS 943
GT + APE+ + + VD+++
Sbjct: 193 ACGTPEYMAPEVF----------------------------------RRTGYGKPVDMWA 218
Query: 944 LGCIFYYVLSKGEHPFG--DRILREANILKGDYRL-DGIKKSIQERSVCIEAADLIKSML 1000
+G I Y++LS G PF ++ IL +Y D I E A D IK L
Sbjct: 219 IGVITYFLLS-GYTPFARPSQVEVIEAILANEYTFNDPCWSGISE-----TAKDFIKKCL 272
Query: 1001 EQNPLLRPASDEILKHP 1017
E +P R + + LKHP
Sbjct: 273 ENDPSKRLTAADALKHP 289
>At5g38210 [T] KOG1187 Serine/threonine protein kinase
Length = 960
Score = 62.4 bits (150), Expect = 4e-09
Identities = 48/188 (25%), Positives = 91/188 (47%), Gaps = 25/188 (13%)
Query: 712 SRVLGYGSSGTVVFQGKFQNRPVAVKRLL---IDFYDIASKEIQLLSESDDHPNVIRYY- 767
S+ LG G GTV + R VAVKRL + + EI +L +S HPN++ Y
Sbjct: 635 SKELGDGGFGTVYYGTLKDGRAVAVKRLFERSLKRVEQFKNEIDIL-KSLKHPNLVILYG 693
Query: 768 -FSESTEKFMYIAVELCSASLEDVIEGSKGLAKNVAVQKNIDPINVLFQITSGVNHLHSM 826
+ + + + + + + +L + + G++ ++ + + + + S +++LH+
Sbjct: 694 CTTRHSRELLLVYEYISNGTLAEHLHGNQAQSRPICWPARLQ---IAIETASALSYLHAS 750
Query: 827 KIVHRDLKPQNILIAPPKRYLSLHASKNKFRVLISDFGLCKKLEIDESSFRTNNFNNPTG 886
I+HRD+K NIL+ + ++V ++DFGL + +D++ T P G
Sbjct: 751 GIIHRDVKTTNILL------------DSNYQVKVADFGLSRLFPMDQTHIST----APQG 794
Query: 887 TSGWRAPE 894
T G+ PE
Sbjct: 795 TPGYVDPE 802
>7298926 [T] KOG0578 p21-activated serine/threonine protein kinase
Length = 704
Score = 62.4 bits (150), Expect = 4e-09
Identities = 81/310 (26%), Positives = 132/310 (42%), Gaps = 73/310 (23%)
Query: 715 LGYGSSGTVVFQGKFQN-RPVAVKRLLIDFY---DIASKEIQLLSESDDHPNVIRYYFSE 770
+G G+SGTV + VA+K++ + ++ EI ++ E+ HPNV+ Y S
Sbjct: 436 IGQGASGTVYTAIESSTGMEVAIKQMNLSQQPKKELIINEILVMRENK-HPNVVNYLDSY 494
Query: 771 STEKFMYIAVE-LCSASLEDVIEGSKGLAKNVAVQKNIDPINVLFQITSGVNHLHSMKIV 829
+ +++ +E L SL DV+ + +A V ++ + LH+ +++
Sbjct: 495 LVSEELWVVMEYLPGGSLTDVVTETCMDEGQIAA--------VCREVLQALEFLHANQVI 546
Query: 830 HRDLKPQNILIAPPKRYLSLHASKNKFRVLISDFGLCKKLEIDESSFRTNNFNNPTGTSG 889
HRD+K NIL L L S V ++DFG C ++ ++S T GT
Sbjct: 547 HRDIKSDNIL-------LGLDGS-----VKLTDFGFCAQISPEQSKRTT-----MVGTPY 589
Query: 890 WRAPEIISGEVSLSESFAXXXXXXXXXXXXXXLDVNHMDLVTKKRLTRAVDIFSLGCIFY 949
W APE+ VT+K+ VD++SLG I
Sbjct: 590 WMAPEV----------------------------------VTRKQYGPKVDLWSLG-IMA 614
Query: 950 YVLSKGEHPFGDRILREANILKGDYRL-DGIKKSIQERSVCIEA-ADLIKSMLEQNPLLR 1007
+ +GE P+ L E N LK Y + K I+E+ A D + LE R
Sbjct: 615 IEMVEGEPPY----LNE-NPLKALYLIATNGKPEIKEKDKLSSAFQDFLDQCLEVEVDRR 669
Query: 1008 PASDEILKHP 1017
++ ++LKHP
Sbjct: 670 ASALDLLKHP 679
>YCL024w [T] KOG0583 Serine/threonine protein kinase
Length = 1037
Score = 62.0 bits (149), Expect = 5e-09
Identities = 69/267 (25%), Positives = 108/267 (39%), Gaps = 76/267 (28%)
Query: 760 HPNVIRYYFSESTEKFMYIAVELCSASLEDVIEGSKGLAKNVAVQKNIDP----INVLFQ 815
HPNV+ Y T +Y+ +E KG N+ V P IN Q
Sbjct: 86 HPNVLSLYDVWETNNNLYLILEYAE----------KGELFNLLVDHGPLPEREAINCFRQ 135
Query: 816 ITSGVNHLHSMKIVHRDLKPQNILIAPPKRYLSLHASKNKFRVLISDFGLCKKLEIDESS 875
I G+++ H++ IVHRDLKP+N+L+ + + + I+DFG+ L+ D
Sbjct: 136 IIIGISYCHALGIVHRDLKPENLLL------------DSFYNIKIADFGMA-ALQTDADL 182
Query: 876 FRTNNFNNPTGTSGWRAPEIISGEVSLSESFAXXXXXXXXXXXXXXLDVNHMDLVTKKRL 935
T+ G+ + APEI+SG E FA
Sbjct: 183 LETS-----CGSPHYAAPEIVSG--LPYEGFAS--------------------------- 208
Query: 936 TRAVDIFSLGCIFYYVLSKGEHPFGDRILREANIL----KGDYRLDGIKKSIQERSVCIE 991
D++S G I + +L+ G PF + ++L KG + + + + +
Sbjct: 209 ----DVWSCGVILFALLT-GRLPFDEENGNVRDLLLKVQKGQFEMP------NDTEISRD 257
Query: 992 AADLIKSMLEQNPLLRPASDEILKHPL 1018
A DLI +L +P R +IL HPL
Sbjct: 258 AQDLIGKILVVDPRQRIKIRDILSHPL 284
>Hs19923464 [T] KOG0577 Serine/threonine protein kinase
Length = 898
Score = 62.0 bits (149), Expect = 5e-09
Identities = 55/199 (27%), Positives = 86/199 (42%), Gaps = 37/199 (18%)
Query: 706 KHLSISSRVLGYGSSGTVVFQ-GKFQNRPVAVKRLLID-------FYDIASKEIQLLSES 757
+ L I +G+GS G V F N VA+K++ + DI KE++ L +
Sbjct: 21 EELFIGLHEIGHGSFGAVYFATNAHTNEVVAIKKMSYSGKQTHEKWQDIL-KEVKFLRQL 79
Query: 758 DDHPNVIRYYFSESTEKFMYIAVELCSASLEDVIEGSKGLAKNVAVQKNIDPINVLFQIT 817
HPN I Y E ++ +E C S D++E K + V + +
Sbjct: 80 K-HPNTIEYKGCYLKEHTAWLVMEYCLGSASDLLEVHKKPLQEVEIAA------ITHGAL 132
Query: 818 SGVNHLHSMKIVHRDLKPQNILIAPPKRYLSLHASKNKFRVLISDFGLCKKLEIDESSFR 877
G+ +LHS ++HRD+K NIL+ P +V ++DFG S+
Sbjct: 133 HGLAYLHSHALIHRDIKAGNILLTEPG------------QVKLADFG---------SASM 171
Query: 878 TNNFNNPTGTSGWRAPEII 896
+ N+ GT W APE+I
Sbjct: 172 ASPANSFVGTPYWMAPEVI 190
>CE29478 [T] KOG0664 Nemo-like MAPK-related serine/threonine protein kinase
Length = 437
Score = 62.0 bits (149), Expect = 5e-09
Identities = 66/254 (25%), Positives = 109/254 (41%), Gaps = 70/254 (27%)
Query: 713 RVLGYGSSGTV-VFQGKFQNRPVAVKRLLIDFYDIAS-----KEIQLLSESDDHPNVIRY 766
R +GYG+ G V + VA+K++ F ++AS +EI++LS S H NV+
Sbjct: 47 RPIGYGAFGVVWSVTDPRSGKRVALKKMPNVFQNLASCKRVFREIKMLS-SFRHDNVLSL 105
Query: 767 Y-----FSESTEKFMYIAVELCSASLEDVIEGSKGLAKNVAVQKNIDPINV-LFQITSGV 820
+ S + +Y+ EL + L +I + L D + V ++QI G+
Sbjct: 106 LDILQPANPSFFQELYVLTELMQSDLHKIIVSPQALTP--------DHVKVFVYQILRGL 157
Query: 821 NHLHSMKIVHRDLKPQNILIAPPKRYLSLHASKNKFRVLISDFGLCKKLEIDESSFRTNN 880
+LH+ I+HRD+KP N+L+ + + I DFGL + + + N
Sbjct: 158 KYLHTANILHRDIKPGNLLV------------NSNCILKICDFGLARTWDQRDRL----N 201
Query: 881 FNNPTGTSGWRAPEIISGEVSLSESFAXXXXXXXXXXXXXXLDVNHMDLVTKKRLTRAVD 940
+ T +RAPE++ G +R T AVD
Sbjct: 202 MTHEVVTQYYRAPELLMG---------------------------------ARRYTGAVD 228
Query: 941 IFSLGCIFYYVLSK 954
I+S+GCIF +L +
Sbjct: 229 IWSVGCIFAELLQR 242
>CE29477 [T] KOG0664 Nemo-like MAPK-related serine/threonine protein kinase
Length = 462
Score = 62.0 bits (149), Expect = 5e-09
Identities = 66/254 (25%), Positives = 109/254 (41%), Gaps = 70/254 (27%)
Query: 713 RVLGYGSSGTV-VFQGKFQNRPVAVKRLLIDFYDIAS-----KEIQLLSESDDHPNVIRY 766
R +GYG+ G V + VA+K++ F ++AS +EI++LS S H NV+
Sbjct: 72 RPIGYGAFGVVWSVTDPRSGKRVALKKMPNVFQNLASCKRVFREIKMLS-SFRHDNVLSL 130
Query: 767 Y-----FSESTEKFMYIAVELCSASLEDVIEGSKGLAKNVAVQKNIDPINV-LFQITSGV 820
+ S + +Y+ EL + L +I + L D + V ++QI G+
Sbjct: 131 LDILQPANPSFFQELYVLTELMQSDLHKIIVSPQALTP--------DHVKVFVYQILRGL 182
Query: 821 NHLHSMKIVHRDLKPQNILIAPPKRYLSLHASKNKFRVLISDFGLCKKLEIDESSFRTNN 880
+LH+ I+HRD+KP N+L+ + + I DFGL + + + N
Sbjct: 183 KYLHTANILHRDIKPGNLLV------------NSNCILKICDFGLARTWDQRDRL----N 226
Query: 881 FNNPTGTSGWRAPEIISGEVSLSESFAXXXXXXXXXXXXXXLDVNHMDLVTKKRLTRAVD 940
+ T +RAPE++ G +R T AVD
Sbjct: 227 MTHEVVTQYYRAPELLMG---------------------------------ARRYTGAVD 253
Query: 941 IFSLGCIFYYVLSK 954
I+S+GCIF +L +
Sbjct: 254 IWSVGCIFAELLQR 267
>CE29476 [T] KOG0664 Nemo-like MAPK-related serine/threonine protein kinase
Length = 634
Score = 62.0 bits (149), Expect = 5e-09
Identities = 66/254 (25%), Positives = 109/254 (41%), Gaps = 70/254 (27%)
Query: 713 RVLGYGSSGTV-VFQGKFQNRPVAVKRLLIDFYDIAS-----KEIQLLSESDDHPNVIRY 766
R +GYG+ G V + VA+K++ F ++AS +EI++LS S H NV+
Sbjct: 244 RPIGYGAFGVVWSVTDPRSGKRVALKKMPNVFQNLASCKRVFREIKMLS-SFRHDNVLSL 302
Query: 767 Y-----FSESTEKFMYIAVELCSASLEDVIEGSKGLAKNVAVQKNIDPINV-LFQITSGV 820
+ S + +Y+ EL + L +I + L D + V ++QI G+
Sbjct: 303 LDILQPANPSFFQELYVLTELMQSDLHKIIVSPQALTP--------DHVKVFVYQILRGL 354
Query: 821 NHLHSMKIVHRDLKPQNILIAPPKRYLSLHASKNKFRVLISDFGLCKKLEIDESSFRTNN 880
+LH+ I+HRD+KP N+L+ + + I DFGL + + + N
Sbjct: 355 KYLHTANILHRDIKPGNLLV------------NSNCILKICDFGLARTWDQRDRL----N 398
Query: 881 FNNPTGTSGWRAPEIISGEVSLSESFAXXXXXXXXXXXXXXLDVNHMDLVTKKRLTRAVD 940
+ T +RAPE++ G +R T AVD
Sbjct: 399 MTHEVVTQYYRAPELLMG---------------------------------ARRYTGAVD 425
Query: 941 IFSLGCIFYYVLSK 954
I+S+GCIF +L +
Sbjct: 426 IWSVGCIFAELLQR 439
>CE23702 [T] KOG4721 Serine/threonine protein kinase contains leucine zipper
domain
Length = 855
Score = 62.0 bits (149), Expect = 5e-09
Identities = 83/318 (26%), Positives = 129/318 (40%), Gaps = 87/318 (27%)
Query: 715 LGYGSSGTVVFQGKFQNRPVAVKRLLIDFYDIASKEIQLLSESDDHPNVIRYYFSESTEK 774
LG GS G V F+G+ +NR VAVK++ + EI+ L H N+I + S
Sbjct: 68 LGSGSQGAV-FRGQLENRTVAVKKV----NQLKETEIKHLRHLR-HQNIIEFLGVCSKSP 121
Query: 775 FMYIAVELCS-ASLEDVIEGSKGLAKNVAVQKNIDPINVLFQITSGVNHLHSMKIVHRDL 833
I +E CS L V++ + + + Q + +I G+++LH K++HRDL
Sbjct: 122 CYCIVMEYCSKGQLCTVLKSRNTITRELFAQW-------VKEIADGMHYLHQNKVIHRDL 174
Query: 834 KPQNILIAPPKRYLSLHASKNKFRVLISDFG---LCKKLEIDESSFRTNNFNNPTGTSGW 890
K NILI+ + + I DFG + KK++ SF GT W
Sbjct: 175 KSPNILISA------------EDSIKICDFGTSHMQKKMDSTMMSF--------CGTVSW 214
Query: 891 RAPEIISGEVSLSESFAXXXXXXXXXXXXXXLDVNHMDLVTKKRLTRAVDIFSLGCIFYY 950
APE+I K+ VD++S G + +
Sbjct: 215 MAPEMIK----------------------------------KQPCNEKVDVYSFGVVLWE 240
Query: 951 VLSKGEHPFGDRILREANILKGDYRLDGIKKSIQERSVCIEAAD----LIKSMLEQNPLL 1006
+L++ E P+ + I + A I G+ +I + EA LIK L Q
Sbjct: 241 MLTR-ETPYAN-IAQMAIIF-------GVGTNILSLPMPEEAPKGLVLLIKQCLSQKGRN 291
Query: 1007 RPASDEILKHPLFWGVSK 1024
RP+ I +H W + K
Sbjct: 292 RPSFSHIRQH---WEIFK 306
>At3g49370 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-Hand protein
superfamily
Length = 594
Score = 62.0 bits (149), Expect = 5e-09
Identities = 72/301 (23%), Positives = 118/301 (38%), Gaps = 70/301 (23%)
Query: 726 QGKFQNRPVAVKRL-------LIDFYDIASKEIQLLSESDDHPNVIRYYFSESTEKFMYI 778
+GK + + VAVK + + D+ +E++LL H +++++Y +++
Sbjct: 163 KGKIKGQTVAVKIISKSKMTSALSIEDVR-REVKLLKALSGHSHMVKFYDVFEDSDNVFV 221
Query: 779 AVELCSAS-LEDVIEGSKGLAKNVAVQKNIDPINVLFQITSGVNHLHSMKIVHRDLKPQN 837
+ELC L D I G ++ +L QI S H +VHRDLKP+N
Sbjct: 222 VMELCEGGELLDSILARGGRYPEAEAKR------ILVQILSATAFFHLQGVVHRDLKPEN 275
Query: 838 ILIAPPKRYLSLHASKNKFRVL-ISDFGLCKKLEIDESSFRTNNFNNPTGTSGWRAPEII 896
L SKN+ VL + DFGL D+ N+ G++ + APE++
Sbjct: 276 FLF----------TSKNEDAVLKVIDFGLSDYARFDQ------RLNDVVGSAYYVAPEVL 319
Query: 897 SGEVSLSESFAXXXXXXXXXXXXXXLDVNHMDLVTKKRLTRAVDIFSLGCIFYYVLSKGE 956
S DI+S+G I Y +L G
Sbjct: 320 HRSYSTE-----------------------------------ADIWSIGVISYILLC-GS 343
Query: 957 HPFGDRILREANILKGDYRLDGIKKSIQERSVCIEAADLIKSMLEQNPLLRPASDEILKH 1016
PF R E+ I + R + + S+ A D +K +L ++ R + + L H
Sbjct: 344 RPFYGR--TESAIFRCVLRANPNFDDLPWPSISPIAKDFVKRLLNKDHRKRMTAAQALAH 401
Query: 1017 P 1017
P
Sbjct: 402 P 402
>At3g05840 [G] KOG0658 Glycogen synthase kinase-3
Length = 409
Score = 62.0 bits (149), Expect = 5e-09
Identities = 82/340 (24%), Positives = 146/340 (42%), Gaps = 86/340 (25%)
Query: 710 ISSRVLGYGSSGTVVFQGKF--QNRPVAVKRLLIDFYDIASKEIQLLSESDDHPNVI--R 765
++ RV+G+GS G VVFQ K VA+K++L D ++E+Q + D HPNV+ +
Sbjct: 74 MAERVVGHGSFG-VVFQAKCLETGETVAIKKVLQD-RRYKNRELQTMRLLD-HPNVVSLK 130
Query: 766 YYFSESTEK---FMYIAVELCSASLEDVIEGSKGLAKNVAVQKNIDPINVLFQITSGVNH 822
+ F +TEK ++ + +E ++ VI+ L + + + + +QI +++
Sbjct: 131 HCFFSTTEKDELYLNLVLEYVPETVHRVIKHYNKLNQRMPL---VYVKLYTYQIFRSLSY 187
Query: 823 LHS-MKIVHRDLKPQNILIAPPKRYLSLHASKNKFRVLISDFGLCKKLEIDESSFRTNNF 881
+H + + HRD+KPQN+L+ P + +V + DFG K L E +
Sbjct: 188 IHRCIGVCHRDIKPQNLLVNP-----------HTHQVKLCDFGSAKVLVKGEPNI----- 231
Query: 882 NNPTGTSGWRAPEIISGEVSLSESFAXXXXXXXXXXXXXXLDVNHMDLVTKKRLTRAVDI 941
+ + +RAPE+I G T A+D+
Sbjct: 232 -SYICSRYYRAPELIFGAT---------------------------------EYTTAIDV 257
Query: 942 FSLGCIF-YYVLSKGEHPFGDRILREANILK-----------------GDYRLDGIK--- 980
+S GC+ +L + P + + I+K +++ IK
Sbjct: 258 WSAGCVLAELLLGQPLFPGESGVDQLVEIIKVLGTPTREEIKCMNPNYTEFKFPQIKAHP 317
Query: 981 -KSIQERSVCIEAADLIKSMLEQNPLLRPASDEILKHPLF 1019
I + + EA DL+ +L+ +P LR A+ + L HP F
Sbjct: 318 WHKIFHKRMPPEAVDLVSRLLQYSPNLRCAALDSLVHPFF 357
>At1g18390 [T] KOG1187 Serine/threonine protein kinase
Length = 605
Score = 62.0 bits (149), Expect = 5e-09
Identities = 49/188 (26%), Positives = 89/188 (47%), Gaps = 25/188 (13%)
Query: 712 SRVLGYGSSGTVVFQGKFQNRPVAVKRLLIDFYDIASK---EIQLLSESDDHPNVIRYY- 767
S+ LG G GTV + R VAVKRL + + A + E+++L+ HPN++ +
Sbjct: 298 SKELGDGGFGTVYYGKLKDGRSVAVKRLYDNNFKRAEQFRNEVEILTGLR-HPNLVALFG 356
Query: 768 -FSESTEKFMYIAVELCSASLEDVIEGSKGLAKNVAVQKNIDPINVLFQITSGVNHLHSM 826
S+ + + + + + +L D + G + ++ + + + S + +LH+
Sbjct: 357 CSSKQSRDLLLVYEYVANGTLADHLHGPQANPSSLPWSIRL---KIAVETASALKYLHAS 413
Query: 827 KIVHRDLKPQNILIAPPKRYLSLHASKNKFRVLISDFGLCKKLEIDESSFRTNNFNNPTG 886
KI+HRD+K NIL+ F V ++DFGL + +D++ T P G
Sbjct: 414 KIIHRDVKSNNILL------------DQNFNVKVADFGLSRLFPMDKTHVST----APQG 457
Query: 887 TSGWRAPE 894
T G+ P+
Sbjct: 458 TPGYVDPD 465
>7295638 [T] KOG0603 Ribosomal protein S6 kinase
Length = 911
Score = 62.0 bits (149), Expect = 5e-09
Identities = 67/277 (24%), Positives = 113/277 (40%), Gaps = 71/277 (25%)
Query: 749 KEIQLLSESDDHPNVIRYYFSESTEKFMYIAVELCSASLEDVIEGSKGLAKNVAVQK--N 806
+E++++ +HPN++ Y Y+ +EL ++G + L + +AV +
Sbjct: 617 EEVEIMLRYGNHPNIVTLYSVYEDAGSAYLVMEL--------LKGGELLDRILAVGQMCE 668
Query: 807 IDPINVLFQITSGVNHLHSMKIVHRDLKPQNILIAPPKRYLSLHASKNKFRVLISDFGLC 866
+ VL I S V +LH +VHRDLKP N++ Y S+ + + + D G
Sbjct: 669 SEASAVLRTIASAVAYLHEHGVVHRDLKPSNMI------YASMRQTPETLK--LCDLGFA 720
Query: 867 KKLEIDESSFRTNNFNNPTGTSGWRAPEIISGEVSLSESFAXXXXXXXXXXXXXXLDVNH 926
K+L D T P T+ + APE++
Sbjct: 721 KQLRADNGLLMT-----PCYTANFVAPEVLK----------------------------- 746
Query: 927 MDLVTKKRLTRAVDIFSLGCIFYYVLSKGEHPFG-------DRILREANILKGDYRLDGI 979
++ A DI+SLG + Y +LS G PF D IL+ + D+
Sbjct: 747 -----RQGYDLACDIWSLGVLLYIMLS-GRTPFASTPNDSPDVILKRIGSGQIDF----- 795
Query: 980 KKSIQERSVCIEAADLIKSMLEQNPLLRPASDEILKH 1016
S + + + A +L++ ML P RP + IL+H
Sbjct: 796 -TSSRWALISVPAKELLRQMLHIVPENRPTAARILEH 831
>YJL106w [T] KOG0661 MAPK related serine/threonine protein kinase
Length = 645
Score = 61.6 bits (148), Expect = 7e-09
Identities = 43/162 (26%), Positives = 78/162 (47%), Gaps = 16/162 (9%)
Query: 740 LIDFYDIASKEIQLLSESDDHPNVIRYYFSESTEKFMYIAVELCSASLEDVIEGSKGLAK 799
L D+ + + L ++DH I F +S ++I +E +L +++ +
Sbjct: 106 LQDYTRVREIKFILAIPANDHLIQIFEVFIDSENYQLHIVMECMEQNLYQMMKHRRRRVF 165
Query: 800 NVAVQKNIDPINVLFQITSGVNHLHSMKIVHRDLKPQNILIAP-----PKRYLSLHASKN 854
++ K+I L QI +G+ H+H HRDLKP+NILI P K Y++ ++
Sbjct: 166 SIPSLKSI-----LSQILAGLKHIHEHNFFHRDLKPENILITPSTQYFEKEYMNQIGYQD 220
Query: 855 KFRVLISDFGLCKKLEIDESSFRTNNFNNPTGTSGWRAPEII 896
+ + ++DFGL + +E N + T +R+PEI+
Sbjct: 221 NYVIKLADFGLARHVE------NKNPYTAYVSTRWYRSPEIL 256
>Hs7662388 [T] KOG0661 MAPK related serine/threonine protein kinase
Length = 632
Score = 61.6 bits (148), Expect = 7e-09
Identities = 69/315 (21%), Positives = 128/315 (39%), Gaps = 46/315 (14%)
Query: 713 RVLGYGSSGTVVFQGKFQNRP-VAVKRLLIDFYD----IASKEIQLLSESDDHPNVIRYY 767
R LG G+ G+V+ ++ +A+K++ FY + +E++ L + + H NV++
Sbjct: 8 RQLGDGTYGSVLLGRSIESGELIAIKKMKRKFYSWEECMNLREVKSLKKLN-HANVVKLK 66
Query: 768 FSESTEKFMYIAVELCSASLEDVIEGSKGLAKNVAVQKNIDPINVLFQITSGVNHLHSMK 827
+Y E +L +I+ L A++ N+++QI G+ +H
Sbjct: 67 EVIRENDHLYFIFEYMKENLYQLIKERNKLFPESAIR------NIMYQILQGLAFIHKHG 120
Query: 828 IVHRDLKPQNILIAPPKRYLSLHASKNKFRVLISDFGLCKKLEIDESSFRTNNFNNPTGT 887
HRDLKP+N+L P+ V I+DFGL +++ + + T
Sbjct: 121 FFHRDLKPENLLCMGPE------------LVKIADFGLAREIRSKPP------YTDYVST 162
Query: 888 SGWRAPEIISGEVSLSESFAXXXXXXXXXXXXXXLDVNHMDLVTKKRL---TRAVDIFSL 944
+RAPE++ + S + ++ T + L +D
Sbjct: 163 RWYRAPEVLLRSTNYSSPI-----------DVWAVGCIMAEVYTLRPLFPGASEIDTIFK 211
Query: 945 GCIFYYVLSKGEHPFGDRILREANILKGDYRLDGIKKSIQERSVCIEAADLIKSMLEQNP 1004
C K + P G ++ N + +K I S EA L++ ML+ +P
Sbjct: 212 ICQVLGTPKKTDWPEGYQLSSAMNFRWPQCVPNNLKTLIPNAS--SEAVQLLRDMLQWDP 269
Query: 1005 LLRPASDEILKHPLF 1019
RP + + L++P F
Sbjct: 270 KKRPTASQALRYPYF 284
>Hs22051130 [G] KOG0658 Glycogen synthase kinase-3
Length = 483
Score = 61.6 bits (148), Expect = 7e-09
Identities = 61/203 (30%), Positives = 99/203 (48%), Gaps = 35/203 (17%)
Query: 713 RVLGYGSSGTVVFQGKFQNRP--VAVKRLLIDFYDIASKEIQLLSESDDHPNVIR--YYF 768
+V+G GS G VV+Q + VA+K++L D ++E+Q++ + D H N++R Y+F
Sbjct: 123 KVIGNGSFG-VVYQARLAETRELVAIKKVLQD-KRFKNRELQIMRKLD-HCNIVRLRYFF 179
Query: 769 SESTEKFMYIAVELCSASLEDVIEGSKGLAKNVAVQKNIDPINV----LFQITSGVNHLH 824
S EK + + L LE V E +A++ K PI ++Q+ + ++H
Sbjct: 180 YSSGEKKDELYLNLV---LEYVPETVYRVARHFTKAKLTIPILYVKVYMYQLFRSLAYIH 236
Query: 825 SMKIVHRDLKPQNILIAPPKRYLSLHASKNKFRVLISDFGLCKKLEIDES--SFRTNNFN 882
S + HRD+KPQN+L+ P L L DFG K+L E S+ + +
Sbjct: 237 SQGVCHRDIKPQNLLVDPDTAVLKL-----------CDFGSAKQLVRGEPNVSYICSRY- 284
Query: 883 NPTGTSGWRAPEIISGEVSLSES 905
+RAPE+I G + S
Sbjct: 285 -------YRAPELIFGATDYTSS 300
>Hs11995474 [G] KOG0658 Glycogen synthase kinase-3
Length = 483
Score = 61.6 bits (148), Expect = 7e-09
Identities = 61/203 (30%), Positives = 99/203 (48%), Gaps = 35/203 (17%)
Query: 713 RVLGYGSSGTVVFQGKFQNRP--VAVKRLLIDFYDIASKEIQLLSESDDHPNVIR--YYF 768
+V+G GS G VV+Q + VA+K++L D ++E+Q++ + D H N++R Y+F
Sbjct: 123 KVIGNGSFG-VVYQARLAETRELVAIKKVLQD-KRFKNRELQIMRKLD-HCNIVRLRYFF 179
Query: 769 SESTEKFMYIAVELCSASLEDVIEGSKGLAKNVAVQKNIDPINV----LFQITSGVNHLH 824
S EK + + L LE V E +A++ K PI ++Q+ + ++H
Sbjct: 180 YSSGEKKDELYLNLV---LEYVPETVYRVARHFTKAKLTIPILYVKVYMYQLFRSLAYIH 236
Query: 825 SMKIVHRDLKPQNILIAPPKRYLSLHASKNKFRVLISDFGLCKKLEIDES--SFRTNNFN 882
S + HRD+KPQN+L+ P L L DFG K+L E S+ + +
Sbjct: 237 SQGVCHRDIKPQNLLVDPDTAVLKL-----------CDFGSAKQLVRGEPNVSYICSRY- 284
Query: 883 NPTGTSGWRAPEIISGEVSLSES 905
+RAPE+I G + S
Sbjct: 285 -------YRAPELIFGATDYTSS 300
>CE29466 [T] KOG0665 Jun-N-terminal kinase (JNK)
Length = 390
Score = 61.6 bits (148), Expect = 7e-09
Identities = 56/196 (28%), Positives = 95/196 (47%), Gaps = 37/196 (18%)
Query: 715 LGYGSSGTVVFQGKF-QNRPVAVKRLLIDFYDIAS-----KEIQLLSESDDHPNVIRYY- 767
L G+ GTVV + VA+K++ F S +E LL+ + HPN+IR
Sbjct: 44 LNAGAQGTVVMADDLVTTQRVAIKKMQQPFVMTMSAKRAYREFILLT-TIKHPNIIRLLN 102
Query: 768 -----FSESTEKFMYIAVELCSASLEDVIEGSKGLAKNVAVQKNIDPINVLFQITSGVNH 822
S ST + +Y+ +EL + +L +VI + K ++ ++Q + H
Sbjct: 103 AFTPDTSLSTFREVYLVMELMTHNLHEVIHRLRLDHKTLSF--------FVYQSLCAIKH 154
Query: 823 LHSMKIVHRDLKPQNILIAPPKRYLSLHASKNKFRVLISDFGLCKKLEIDESSFRTNNFN 882
LH+ ++HRDLKP NI++ ++ + + DFGL +K +D +S R +++
Sbjct: 155 LHNSGVIHRDLKPSNIVV------------NDRCVLKVLDFGLARKKNVD-TSMRMSDY- 200
Query: 883 NPTGTSGWRAPEIISG 898
T +RAPE+I G
Sbjct: 201 --VVTRYYRAPEVILG 214
>CE28168 [T] KOG0194 Protein tyrosine kinase
Length = 395
Score = 61.6 bits (148), Expect = 7e-09
Identities = 58/191 (30%), Positives = 92/191 (47%), Gaps = 39/191 (20%)
Query: 715 LGYGSSGTVVFQGKF--QNRPVAVKRLLIDFYDIAS-----KEIQLLSESDDHPNVIRYY 767
LG G+ GTV + G+ N +AVK+L + D S KE +++ + DHPN++++Y
Sbjct: 126 LGSGAYGTV-YLGRLTKNNTKIAVKKLDTEGNDEESLAEMMKEARVM-QLYDHPNIVKFY 183
Query: 768 FSESTEKFMYIAVELCSA-SLED--VIEGSKGLAKNVAVQKNIDPINVLFQITSGVNHLH 824
+ + +ELC+ S+ED V +G+K K I + G+ +LH
Sbjct: 184 GYIVDDIPYLLVLELCNGGSVEDKLVEKGAKLSTKT--------RIMYTYHAACGIEYLH 235
Query: 825 SMKIVHRDLKPQNILIAPPKRYLSLHASKNKFRVLISDFGLCKKLEIDESSFRTNNFNNP 884
K +HRD+ +N LI +K V I+DFG+C+ +S + N P
Sbjct: 236 KKKCIHRDIAARNCLI-------------HKEIVKIADFGMCR-----ATSIYKVDLNKP 277
Query: 885 TGTSGWRAPEI 895
T T W APE+
Sbjct: 278 TNTR-WLAPEV 287
>At4g04710 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-Hand protein
superfamily
Length = 575
Score = 61.6 bits (148), Expect = 7e-09
Identities = 72/318 (22%), Positives = 122/318 (37%), Gaps = 64/318 (20%)
Query: 750 EIQLLSESDDHPNVIRYYFSESTEKFMYIAVELCSASLEDVIEGSKGLAKNVAVQKNIDP 809
EIQ++ PN+++ S ++I +ELC ++ + L K+ + D
Sbjct: 70 EIQIMDHVSGQPNIVQIKGSYEDNNSIHIVMELCGGG--ELFDKIDALVKSHSYYSEKDA 127
Query: 810 INVLFQITSGVNHLHSMKIVHRDLKPQNILIAPPKRYLSLHASKNKFRVLISDFGLCKKL 869
+ I + V HS+ +VHRDLKP+N L + L A DFG +
Sbjct: 128 AGIFRSIVNAVKICHSLDVVHRDLKPENFLFSSKDENAMLKA---------IDFGCSVYI 178
Query: 870 EIDESSFRTNNFNNPTGTSGWRAPEIISGEVSLSESFAXXXXXXXXXXXXXXLDVNHMDL 929
+ F G+ + APE++ G
Sbjct: 179 K------EGKTFERVVGSKYYIAPEVLEGSYG---------------------------- 204
Query: 930 VTKKRLTRAVDIFSLGCIFYYVLSKGEHPF--GDRILREANILKGDYRLDGIKKSIQERS 987
+ +DI+S G I Y +LS G PF G + + + D + + + +
Sbjct: 205 -------KEIDIWSAGVILYILLS-GVPPFQTGIESIIVSTLCIVDAEIKECRLDFESQP 256
Query: 988 ---VCIEAADLIKSMLEQNPLLRPASDEILKHPLFWGVSKKLEFLLKVSDRFEVERRDPP 1044
+ +A LI ML + P R ++ ++L+HP W K E K D + R
Sbjct: 257 WPLISFKAKHLIGKMLTKKPKERISAADVLEHP--W---MKSEAPDKPIDNVVLSRM-KQ 310
Query: 1045 SPLLLKLEEVSAKVITTG 1062
+ KL++++ KVI G
Sbjct: 311 FRAMNKLKKLALKVIAEG 328
>At1g76040 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-Hand protein
superfamily
Length = 534
Score = 61.6 bits (148), Expect = 7e-09
Identities = 71/297 (23%), Positives = 127/297 (41%), Gaps = 73/297 (24%)
Query: 737 KRLLIDFYDIAS--KEIQLLSESDDHPNVIRYYFSESTEKFMYIAVELCSAS--LEDVIE 792
KR LI DI +E+ +L PN++ + + + +++ +ELCS + +I+
Sbjct: 118 KRKLIRRKDIEDVRREVMILQHLTGQPNIVEFRGAYEDKDNLHLVMELCSGGELFDRIIK 177
Query: 793 GSKGLAKNVAVQKNIDPINVLFQITSGVNHLHSMKIVHRDLKPQNILIAPPKRYLSLHAS 852
K A N+ QI + V+ H M +VHRDLKP+N L+ ++
Sbjct: 178 KGSYSEKEAA--------NIFRQIVNVVHVCHFMGVVHRDLKPENFLLV---------SN 220
Query: 853 KNKFRVLISDFGLCKKLEIDESSFRTNNFNNPTGTSGWRAPEIISGEVSLSESFAXXXXX 912
+ + +DFGL + I+E + + G++ + APE++
Sbjct: 221 EEDSPIKATDFGL--SVFIEEGKV----YRDIVGSAYYVAPEVL---------------- 258
Query: 913 XXXXXXXXXLDVNHMDLVTKKRLTRAVDIFSLGCIFYYVLSKGEHPF---GDRILREANI 969
+ + +D++S G + Y +LS G PF ++ + EA I
Sbjct: 259 -------------------HRNYGKEIDVWSAGVMLYILLS-GVPPFWGETEKTIFEA-I 297
Query: 970 LKGDYRLDGIKKSIQERSVCIEAADLIKSMLEQNPLLRPASDEILKHPLFWGVSKKL 1026
L+G L+ + ++ A DLI+ ML ++P R + E L+HP W K+
Sbjct: 298 LEGKLDLE----TSPWPTISESAKDLIRKMLIRDPKKRITAAEALEHP--WMTDTKI 348
>YBR274w [D] KOG0590 Checkpoint kinase and related serine/threonine protein
kinases
Length = 527
Score = 61.2 bits (147), Expect = 9e-09
Identities = 52/180 (28%), Positives = 88/180 (48%), Gaps = 25/180 (13%)
Query: 722 TVVFQGKFQNRPVAVKRLLIDFYDIASKEIQLLSESDDHPNVIRYYFSESTEKFMYIAVE 781
+++ KF + P K L D DI +KE+ L S+ HPNV+R ++++M+I +E
Sbjct: 39 SIILAVKFIHVPTCKKMGLSD-KDI-TKEVVLQSKCSKHPNVLRLIDCNVSKEYMWIILE 96
Query: 782 LC-SASLEDVIEGSKGLAKNVAVQKNIDPINVLFQITSGVNHLH-SMKIVHRDLKPQNIL 839
+ L D IE G+ +VA Q+ S +N+LH + HRD+KP+NIL
Sbjct: 97 MADGGDLFDKIEPDVGVDSDVAQ-------FYFQQLVSAINYLHVECGVAHRDIKPENIL 149
Query: 840 IAPPKRYLSLHASKNKFRVLISDFGLCKKLEIDESSFRTNNFNNPTGTSGWRAPEIISGE 899
+ KN + ++DFGL + + + R + + G+ + APE++ E
Sbjct: 150 L-----------DKNG-NLKLADFGLASQFRRKDGTLRVS--MDQRGSPPYMAPEVLYSE 195
>Hs4505569 [R] KOG0593 Predicted protein kinase KKIAMRE
Length = 493
Score = 61.2 bits (147), Expect = 9e-09
Identities = 56/198 (28%), Positives = 89/198 (44%), Gaps = 30/198 (15%)
Query: 714 VLGYGSSGTVV-FQGKFQNRPVAVKRLLIDFYD-----IASKEIQLLSESDDHPNVIRYY 767
++G GS G V+ + K R VA+K+ L D IA +EI+LL + H N++
Sbjct: 9 LVGEGSYGMVMKCRNKDTGRIVAIKKFLESDDDKMVKKIAMREIKLLKQLR-HENLVNLL 67
Query: 768 FSESTEKFMYIAVELCSASLEDVIEGSKGLAKNVAVQKNIDPINVLFQITSGVNHLHSMK 827
+K Y+ E ++ D +E VQK LFQI +G+ HS
Sbjct: 68 EVCKKKKRWYLVFEFVDHTILDDLELFPNGLDYQVVQK------YLFQIINGIGFCHSHN 121
Query: 828 IVHRDLKPQNILIAPPKRYLSLHASKNKFRVLISDFGLCKKLEIDESSFRTNNFNNPTGT 887
I+HRD+KP+NIL++ V + DFG + L + + T
Sbjct: 122 IIHRDIKPENILVS------------QSGVVKLCDFGFARTLAAPGEV-----YTDYVAT 164
Query: 888 SGWRAPEIISGEVSLSES 905
+RAPE++ G+V ++
Sbjct: 165 RWYRAPELLVGDVKYGKA 182
>Hs19923468 [T] KOG4236 Serine/threonine protein kinase PKC mu/PKD and related
proteins
Length = 878
Score = 61.2 bits (147), Expect = 9e-09
Identities = 87/314 (27%), Positives = 130/314 (40%), Gaps = 74/314 (23%)
Query: 714 VLGYGSSGTVVFQGKFQN--RPVAVKRLLIDFYDIASK-EIQLLSE-----SDDHPNVIR 765
VLG G G VV+ GK + R VAVK +ID +K E QL +E S HP ++
Sbjct: 556 VLGSGQFG-VVYGGKHRKTGRDVAVK--VIDKLRFPTKQESQLRNEVAILQSLRHPGIVN 612
Query: 766 YY-FSESTEKFMYIAVELCSASLEDVIEGSKGLAKNVAVQKNIDPINVLFQITSGVNHLH 824
E+ EK + +L LE ++ KG + ++ QI + HLH
Sbjct: 613 LECMFETPEKVFVVMEKLHGDMLEMILSSEKGRLPERLTKF------LITQILVALRHLH 666
Query: 825 SMKIVHRDLKPQNILIAPPKRYLSLHASKNKF-RVLISDFGLCKKLEIDESSFRTNNFNN 883
IVH DLKP+N+L+ AS + F +V + DFG + I E SFR +
Sbjct: 667 FKNIVHCDLKPENVLL----------ASADPFPQVKLCDFGFAR--IIGEKSFR----RS 710
Query: 884 PTGTSGWRAPEIISGEVSLSESFAXXXXXXXXXXXXXXLDVNHMDLVTKKRLTRAVDIFS 943
GT + APE++ L++ + R++D++S
Sbjct: 711 VVGTPAYLAPEVL-----LNQGY-----------------------------NRSLDMWS 736
Query: 944 LGCIFYYVLSKGEHPFGDRILREANILKGDYRLDGIKKSIQERSVCIEAADLIKSMLEQN 1003
+G I Y LS G PF + I + S + A DLI ++L+
Sbjct: 737 VGVIMYVSLS-GTFPFNEDEDINDQIQNAAFMYPASPWS----HISAGAIDLINNLLQVK 791
Query: 1004 PLLRPASDEILKHP 1017
R + D+ L HP
Sbjct: 792 MRKRYSVDKSLSHP 805
>ECU11g1500 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 300
Score = 61.2 bits (147), Expect = 9e-09
Identities = 63/190 (33%), Positives = 92/190 (48%), Gaps = 18/190 (9%)
Query: 713 RVLGYGSSGTV-VFQGKFQNRP-VAVKRLLIDFYDIASKEIQLLSESDDHPNVIRYYFSE 770
R L G+ GTV + + + R VA K +L + A KE+++LS S H V+R
Sbjct: 23 RRLSRGAHGTVYLLETEAPTREKVACKSMLKRYRRYAEKEVEMLS-SISHRRVVRLLDFF 81
Query: 771 STEKFMYIAVELCS-ASLEDVIEGSKGLAKNVAVQKNIDPINVLFQITSGVNHLHSMKIV 829
T+ + I +E + SL ++IE VA +VL Q G+ +LHS +I+
Sbjct: 82 PTKSGLSIILEYLNYGSLHEMIEYLMENGYRVAGDL---VWSVLAQAADGLRYLHSKQII 138
Query: 830 HRDLKPQNILIAPPKRYLSLHASKNKFRVLISDFGLCKKLEIDESSFRTNNFNNPTGTSG 889
HRD+KP NIL+ R L +F+ + DF L K L ES GT
Sbjct: 139 HRDVKPSNILM---NRTLVQKEELLEFK--LCDFSLAKNLCGKES------VCGIVGTPS 187
Query: 890 WRAPEIISGE 899
+ APE++SGE
Sbjct: 188 YMAPEVVSGE 197
>7297578 [T] KOG0661 MAPK related serine/threonine protein kinase
Length = 822
Score = 61.2 bits (147), Expect = 9e-09
Identities = 76/320 (23%), Positives = 133/320 (40%), Gaps = 50/320 (15%)
Query: 715 LGYGSSGTVVF-QGKFQNRPVAVKRLLIDFYD----IASKEIQLLSESDDHPNVIRYYFS 769
LG G+ GTVV Q K VA+KR+ +Y + +E++ L + HPN+++
Sbjct: 10 LGDGTYGTVVLGQRKDTGEKVAIKRMKRKYYSWEEAMNLREVKSLKKLS-HPNIVKLKEV 68
Query: 770 ESTEKFMYIAVELCSASLEDVIEGSKGLAKNVAVQKNIDPINVLFQITSGVNHLHSMKIV 829
+Y E +L +I+ ++ ++LFQ+ +G+ +H
Sbjct: 69 IRENDTLYFVFEYMKENLYQMIKDRDTHLPEPELK------SILFQVLTGLAFMHRHGFF 122
Query: 830 HRDLKPQNILIAPPKRYLSLHASKNKFRVLISDFGLCKKLEIDESSFRTNNFNNPTGTSG 889
HRDLKP+N+L + P + I+DFGL +++ F + T
Sbjct: 123 HRDLKPENLLCSGPD------------LIKIADFGLAREIR------SRPPFTDYVSTRW 164
Query: 890 WRAPEIISGEVSLSESFAXXXXXXXXXXXXXXLDVNHMDLVTKKRL---TRAVDIFSLGC 946
+RAPE++ + + + +L T + L + VD C
Sbjct: 165 YRAPEVLLHSTNYGSTI-----------DLWAMGCIMAELYTFRPLFPGSSEVDQLFKIC 213
Query: 947 IFYYVLSKGEHPFGDRILREANILKGDYRLDGIKKSIQE-RSVCIE-AADLIKSMLEQNP 1004
K + P G R+ A+++ Y D IK + S C + DL++ ML +P
Sbjct: 214 SVLGTPDKDDWPDGYRL---ASMIHFRYP-DCIKVPLSSVVSRCSQNGLDLLEDMLAYDP 269
Query: 1005 LLRPASDEILKHPLFWGVSK 1024
RP + + LK+P F + +
Sbjct: 270 DKRPTAQQSLKYPYFHALKR 289
>7292249 [T] KOG0587 Traf2- and Nck-interacting kinase and related germinal
center kinase (GCK) family protein kinases
Length = 979
Score = 61.2 bits (147), Expect = 9e-09
Identities = 52/195 (26%), Positives = 94/195 (47%), Gaps = 34/195 (17%)
Query: 714 VLGYGSSGTVVFQGKF----QNRPVAVKRLLIDFYDIASKEIQLLSESDDHPNVIRYYFS 769
V+G G+ G V ++G+ Q + V + D + EI +L + +H N+ YY +
Sbjct: 37 VVGNGTYGQV-YKGRHTKTGQLAAIKVMDVTEDEEEEIKLEINVLKKYSNHRNIATYYGA 95
Query: 770 ------ESTEKFMYIAVELCSA-SLEDVIEGSKGLAKNVAVQKNIDPINVLFQITSGVNH 822
+ +++ +E C A S+ D+++ +KG + K + +I G+++
Sbjct: 96 FIKKSPPGKDDQLWLVMEYCGAGSVTDLVKSTKGQSL-----KEEWIAYICREILRGLSY 150
Query: 823 LHSMKIVHRDLKPQNILIAPPKRYLSLHASKNKFRVLISDFGLCKKLEIDESSFRTNNFN 882
LHS K++HRD+K QN+L+ + V + DFG+ ++D + R N F
Sbjct: 151 LHSNKVIHRDIKGQNVLLT------------DNAEVKLVDFGV--SAQLDRTIGRRNTF- 195
Query: 883 NPTGTSGWRAPEIIS 897
GT W APE+I+
Sbjct: 196 --IGTPYWMAPEVIA 208
>YDR477w [T] KOG0583 Serine/threonine protein kinase
Length = 633
Score = 60.8 bits (146), Expect = 1e-08
Identities = 69/262 (26%), Positives = 105/262 (39%), Gaps = 69/262 (26%)
Query: 760 HPNVIRYYFSESTEKFMYIAVELCSASLEDVIEGSKGLAKNVAVQKNIDPINVLFQITSG 819
HP++I+ Y ++ + + +E L D I +++ A + QI S
Sbjct: 112 HPHIIKLYDVIKSKDEIIMVIEYAGNELFDYIVQRDKMSEQEARR-------FFQQIISA 164
Query: 820 VNHLHSMKIVHRDLKPQNILIAPPKRYLSLHASKNKFRVLISDFGLCKKLEIDESSFRTN 879
V + H KIVHRDLKP+N+L+ V I+DFGL + D + +T+
Sbjct: 165 VEYCHRHKIVHRDLKPENLLL------------DEHLNVKIADFGL-SNIMTDGNFLKTS 211
Query: 880 NFNNPTGTSGWRAPEIISGEVSLSESFAXXXXXXXXXXXXXXLDVNHMDLVTKKRLTRAV 939
G+ + APE+ISG++ V
Sbjct: 212 -----CGSPNYAAPEVISGKLYAGPE---------------------------------V 233
Query: 940 DIFSLGCIFYYVLSKGEHPFGDRILRE--ANILKGDYRLDGIKKSIQERSVCIEAADLIK 997
D++S G I Y +L + PF D + NI G Y L + + AA LIK
Sbjct: 234 DVWSCGVILYVMLCR-RLPFDDESIPVLFKNISNGVYTL--------PKFLSPGAAGLIK 284
Query: 998 SMLEQNPLLRPASDEILKHPLF 1019
ML NPL R + EI++ F
Sbjct: 285 RMLIVNPLNRISIHEIMQDDWF 306
>Hs5454094 [T] KOG0574 STE20-like serine/threonine kinase MST
Length = 491
Score = 60.8 bits (146), Expect = 1e-08
Identities = 57/187 (30%), Positives = 91/187 (48%), Gaps = 31/187 (16%)
Query: 715 LGYGSSGTVVFQG--KFQNRPVAVKRLLI--DFYDIASKEIQLLSESDDHPNVIRYYFSE 770
LG GS G+V F+ K + VA+K++ + D +I KEI ++ + D P V++YY S
Sbjct: 33 LGEGSYGSV-FKAIHKESGQVVAIKQVPVESDLQEII-KEISIMQQCDS-PYVVKYYGSY 89
Query: 771 STEKFMYIAVELCSA-SLEDVIEGSKGLAKNVAVQKNIDPINVLFQITSGVNHLHSMKIV 829
++I +E C A S+ D+I L ++ I +L G+ +LH M+ +
Sbjct: 90 FKNTDLWIVMEYCGAGSVSDIIR----LRNKTLIEDEI--ATILKSTLKGLEYLHFMRKI 143
Query: 830 HRDLKPQNILIAPPKRYLSLHASKNKFRVLISDFGLCKKLEIDESSFRTNNFNNPTGTSG 889
HRD+K NIL+ + ++DFG+ +L D + R N GT
Sbjct: 144 HRDIKAGNILL------------NTEGHAKLADFGVAGQL-TDTMAKR----NTVIGTPF 186
Query: 890 WRAPEII 896
W APE+I
Sbjct: 187 WMAPEVI 193
>Hs20479818 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-Hand protein
superfamily
Length = 514
Score = 60.8 bits (146), Expect = 1e-08
Identities = 82/348 (23%), Positives = 148/348 (41%), Gaps = 82/348 (23%)
Query: 702 EGHLKHLSISS-----------RVLGYGSSGTVV------FQGKFQNRPVAVKRLLIDFY 744
EG + H+ I + R+LG GS G V+ + K+ + V ++
Sbjct: 98 EGKVPHIRIENGAAIEEIYTFGRILGKGSFGIVIEATDKETETKWAIKKVNKEKAGSSAV 157
Query: 745 DIASKEIQLLSESDDHPNVIRYYFSESTEKFMYIAVELCS-ASLEDVIEGSKGLAKNVAV 803
+ +E+ +L +S H ++I T K MY+ +ELC L+++++ ++N
Sbjct: 158 KLLEREVNIL-KSVKHEHIIHLEQVFETPKKMYLVMELCEDGELKEILDRKGHFSEN--- 213
Query: 804 QKNIDPINVLFQITSGVNHLHSMKIVHRDLKPQNILIAPPKRYLSLHASKNKFRVLISDF 863
+ ++ + S + +LH+ IVHRDLK +NI++ K L ++ + ++DF
Sbjct: 214 ----ETRWIIQSLASAIAYLHNNDIVHRDLKLENIMV---KSSLIDDNNEINLNIKVTDF 266
Query: 864 GLC-KKLEIDESSFRTNNFNNPTGTSGWRAPEIISGEVSLSESFAXXXXXXXXXXXXXXL 922
GL KK E+ + GT + APE+IS
Sbjct: 267 GLAVKKQSRSEAMLQAT-----CGTPIYMAPEVISAH----------------------- 298
Query: 923 DVNHMDLVTKKRLTRAVDIFSLGCIFYYVLSKGEHPF---GDRILREANILKGDYRLD-G 978
++ DI+S+G + Y +L +GE PF + L E I KG+ +
Sbjct: 299 -----------DYSQQCDIWSIGVVMYMLL-RGEPPFLASSEEKLFEL-IRKGELHFENA 345
Query: 979 IKKSIQERSVCIEAADLIKSMLEQNPLLRPASDEILKHPLFWGVSKKL 1026
+ SI + C A ++K +++ +P R + E+L + W KL
Sbjct: 346 VWNSISD---C--AKSVLKQLMKVDPAHRITAKELLDNQ--WLTGNKL 386
>Hs20469855 [T] KOG0196 Tyrosine kinase EPH (ephrin) receptor family
Length = 1037
Score = 60.8 bits (146), Expect = 1e-08
Identities = 72/273 (26%), Positives = 110/273 (39%), Gaps = 69/273 (25%)
Query: 698 EFEQEGHLKHLSISSRVLGYGS-----SGTVVFQGKFQNRPVAVKRLLIDFYDIASKEIQ 752
EF +E ++I RV+G G SG + GK + PVA+K L + + + ++
Sbjct: 665 EFAKEIEASCITIE-RVIGAGEFGEVCSGRLKLPGK-RELPVAIKTLKVGYTEKQRRDF- 721
Query: 753 LLSESD-----DHPNVIRYYFSESTEKFMYIAVELCSASLEDVIEGSKGLAKNVAVQKNI 807
L E+ DHPN+I + K + I E D L KN I
Sbjct: 722 -LGEASIMGQFDHPNIIHLEGVVTKSKPVMIVTEYMENGSLDTF-----LKKNDGQFTVI 775
Query: 808 DPINVLFQITSGVNHLHSMKIVHRDLKPQNILIAPPKRYLSLHASKNKFRVLISDFGLCK 867
+ +L I++G+ +L M VHRDL +NILI + +SDFGL +
Sbjct: 776 QLVGMLRGISAGMKYLSDMGYVHRDLAARNILI------------NSNLVCKVSDFGLSR 823
Query: 868 KLEID-ESSFRTNNFNNPTGTSGWRAPEIISGEVSLSESFAXXXXXXXXXXXXXXLDVNH 926
LE D E+++ T P W APE I+
Sbjct: 824 VLEDDPEAAYTTRGGKIPI---RWTAPEAIA----------------------------- 851
Query: 927 MDLVTKKRLTRAVDIFSLGCIFYYVLSKGEHPF 959
++ T A D++S G + + V+S GE P+
Sbjct: 852 -----FRKFTSASDVWSYGIVMWEVVSYGERPY 879
>Hs16178962 [T] KOG0574 STE20-like serine/threonine kinase MST
Length = 491
Score = 60.8 bits (146), Expect = 1e-08
Identities = 57/187 (30%), Positives = 91/187 (48%), Gaps = 31/187 (16%)
Query: 715 LGYGSSGTVVFQG--KFQNRPVAVKRLLI--DFYDIASKEIQLLSESDDHPNVIRYYFSE 770
LG GS G+V F+ K + VA+K++ + D +I KEI ++ + D P V++YY S
Sbjct: 33 LGEGSYGSV-FKAIHKESGQVVAIKQVPVESDLQEII-KEISIMQQCDS-PYVVKYYGSY 89
Query: 771 STEKFMYIAVELCSA-SLEDVIEGSKGLAKNVAVQKNIDPINVLFQITSGVNHLHSMKIV 829
++I +E C A S+ D+I L ++ I +L G+ +LH M+ +
Sbjct: 90 FKNTDLWIVMEYCGAGSVSDIIR----LRNKTLIEDEI--ATILKSTLKGLEYLHFMRKI 143
Query: 830 HRDLKPQNILIAPPKRYLSLHASKNKFRVLISDFGLCKKLEIDESSFRTNNFNNPTGTSG 889
HRD+K NIL+ + ++DFG+ +L D + R N GT
Sbjct: 144 HRDIKAGNILL------------NTEGHAKLADFGVAGQL-TDTMAKR----NTVIGTPF 186
Query: 890 WRAPEII 896
W APE+I
Sbjct: 187 WMAPEVI 193
>Hs11496279 [T] KOG0661 MAPK related serine/threonine protein kinase
Length = 623
Score = 60.8 bits (146), Expect = 1e-08
Identities = 74/315 (23%), Positives = 121/315 (37%), Gaps = 46/315 (14%)
Query: 713 RVLGYGSSGTVVF-QGKFQNRPVAVKRLLIDFYD----IASKEIQLLSESDDHPNVIRYY 767
R LG G+ G+V+ + VA+KR+ FY + +E++ L + + H NVI+
Sbjct: 8 RQLGDGTYGSVLMGKSNESGELVAIKRMKRKFYSWDECMNLREVKSLKKLN-HANVIKLK 66
Query: 768 FSESTEKFMYIAVELCSASLEDVIEGSKGLAKNVAVQKNIDPINVLFQITSGVNHLHSMK 827
+Y E +L +++ L ++ N+++QI G+ +H
Sbjct: 67 EVIRENDHLYFIFEYMKENLYQLMKDRNKLFPESVIR------NIMYQILQGLAFIHKHG 120
Query: 828 IVHRDLKPQNILIAPPKRYLSLHASKNKFRVLISDFGLCKKLEIDESSFRTNNFNNPTGT 887
HRD+KP+N+L P+ V I+DFGL ++L + + T
Sbjct: 121 FFHRDMKPENLLCMGPE------------LVKIADFGLARELRSQPP------YTDYVST 162
Query: 888 SGWRAPEIISGEVSLSESFAXXXXXXXXXXXXXXLDVNHMDLVTKKRL---TRAVDIFSL 944
+RAPE++ S +L + L T VD
Sbjct: 163 RWYRAPEVLLRSSVYSSPIDVWAVGSIMA-----------ELYMLRPLFPGTSEVDEIFK 211
Query: 945 GCIFYYVLSKGEHPFGDRILREANILKGDYRLDGIKKSIQERSVCIEAADLIKSMLEQNP 1004
C K + P G ++ N +K I S EA L+ ML +P
Sbjct: 212 ICQVLGTPKKSDWPEGYQLASSMNFRFPQCVPINLKTLIPNAS--NEAIQLMTEMLNWDP 269
Query: 1005 LLRPASDEILKHPLF 1019
RP + + LKHP F
Sbjct: 270 KKRPTASQALKHPYF 284
>CE00315 [R] KOG0594 Protein kinase PCTAIRE and related kinases
Length = 332
Score = 60.8 bits (146), Expect = 1e-08
Identities = 65/251 (25%), Positives = 108/251 (42%), Gaps = 71/251 (28%)
Query: 715 LGYGSSGTVVFQGKFQ--NRPVAVKRLLIDFYD-----IASKEIQLLSESDDHPNVIRYY 767
+G G+ G VV++GK + N VA+K++ ++ D A +EI LL E HPNV+
Sbjct: 28 IGEGTYG-VVYKGKNRRTNAMVAMKKIRLESEDEGVPSTAVREISLLKELQ-HPNVVGLE 85
Query: 768 FSESTEKFMYIAVELCSASLEDVIEGSKGLAKNVAVQKNIDPINVL----FQITSGVNHL 823
E +++ E S L+ ++ L K+ + P+ L FQI +
Sbjct: 86 AVIMQENRLFLIFEFLSFDLKRYMDQ---LGKDEYL-----PLETLKSYTFQILQAMCFC 137
Query: 824 HSMKIVHRDLKPQNILIAPPKRYLSLHASKNKFRVLISDFGLCKKLEIDESSFRTNNFNN 883
H +++HRDLKPQN+L+ N + ++DFGL + + I + +
Sbjct: 138 HQRRVIHRDLKPQNLLV------------DNNGAIKLADFGLARAIGIP-----IRVYTH 180
Query: 884 PTGTSGWRAPEIISGEVSLSESFAXXXXXXXXXXXXXXLDVNHMDLVTKKRLTRAVDIFS 943
T +RAPEI+ G +R + VD++S
Sbjct: 181 EVVTLWYRAPEILMG---------------------------------AQRYSMGVDMWS 207
Query: 944 LGCIFYYVLSK 954
+GCIF + +K
Sbjct: 208 IGCIFAEMATK 218
>7295173 [T] KOG0664 Nemo-like MAPK-related serine/threonine protein kinase
Length = 474
Score = 60.8 bits (146), Expect = 1e-08
Identities = 68/259 (26%), Positives = 107/259 (41%), Gaps = 80/259 (30%)
Query: 713 RVLGYGSSGTV-VFQGKFQNRPVAVKRLLIDFYDIAS-----KEIQLLSESDDHPNVIRY 766
R +GYG+ G V R VA+K+L F + S +E+++L H NV+
Sbjct: 44 RPIGYGAFGVVWAVTDPRDGRRVALKKLPNVFQSLVSSKRVFRELKMLCFFK-HENVLSA 102
Query: 767 ----------YFSESTEKFMYIAVELCSASLEDVIEGSKGLAKNVAVQKNIDPINV-LFQ 815
+F E +Y+ EL + L +I + L+ D I V L+Q
Sbjct: 103 LDILQPPHLDFFQE-----IYVITELLQSDLHKIIVSPQHLSA--------DHIKVFLYQ 149
Query: 816 ITSGVNHLHSMKIVHRDLKPQNILIAPPKRYLSLHASKNKFRVLISDFGLCKKLEIDESS 875
I G+ +LHS +I+HRD+KP N+L+ + + I DFGL + E D++
Sbjct: 150 ILRGLKYLHSARILHRDIKPGNLLV------------NSNCVLKICDFGLARVEEPDQAK 197
Query: 876 FRTNNFNNPTGTSGWRAPEIISGEVSLSESFAXXXXXXXXXXXXXXLDVNHMDLVTKKRL 935
T T +RAPEI+ G +
Sbjct: 198 HMTQE----VVTQYYRAPEILMG---------------------------------ARHY 220
Query: 936 TRAVDIFSLGCIFYYVLSK 954
+ AVD++S+GCIF +L +
Sbjct: 221 SSAVDVWSVGCIFGELLGR 239
>SPCC16C4.11 [R] KOG0594 Protein kinase PCTAIRE and related kinases
Length = 288
Score = 60.5 bits (145), Expect = 2e-08
Identities = 55/195 (28%), Positives = 89/195 (45%), Gaps = 34/195 (17%)
Query: 721 GTVVFQGKFQNRP----VAVKRLLIDFYD----IASKEIQLLSESDDHPNVIRYYFSEST 772
GT K QNR VA+K + ID + A +EI L+ E HPN++ T
Sbjct: 12 GTYAHVYKGQNRVTGEIVALKVIRIDADEGTPSTAIREISLMKELR-HPNIMSLSDVLQT 70
Query: 773 EKFMYIAVELCSASLEDVIE--GSKGLAKNVAVQKNIDPINVLFQITSGVNHLHSMKIVH 830
E + + E L+ ++ G++G V+ N Q+ G++ H +++H
Sbjct: 71 ENKLMLVFEYMEKDLKKYMDTYGNQGALPPSQVK------NFTQQLLKGISFCHENRVLH 124
Query: 831 RDLKPQNILIAPPKRYLSLHASKNKFRVLISDFGLCKKLEIDESSFRTNNFNNPTGTSGW 890
RDLKPQN+LI ++ + ++DFGL + + I N F+N T +
Sbjct: 125 RDLKPQNLLI------------NSRGELKLADFGLARSIGIP-----VNTFSNEVVTLWY 167
Query: 891 RAPEIISGEVSLSES 905
RAP+++ G S S
Sbjct: 168 RAPDVLLGSRVYSTS 182
>Hs5454096 [T] KOG0574 STE20-like serine/threonine kinase MST
Length = 487
Score = 60.5 bits (145), Expect = 2e-08
Identities = 58/187 (31%), Positives = 93/187 (49%), Gaps = 31/187 (16%)
Query: 715 LGYGSSGTVVFQ-GKFQNRPVAVKRLLI--DFYDIASKEIQLLSESDDHPNVIRYYFSES 771
LG GS G+V K + VA+K++ + D +I KEI ++ + D P+V++YY S
Sbjct: 36 LGEGSYGSVYKAIHKETGQIVAIKQVPVESDLQEII-KEISIMQQCDS-PHVVKYYGSYF 93
Query: 772 TEKFMYIAVELCSA-SLEDVIEGSKGLAKNVAVQKNIDPINVLFQIT-SGVNHLHSMKIV 829
++I +E C A S+ D+I +N + + D I + Q T G+ +LH M+ +
Sbjct: 94 KNTDLWIVMEYCGAGSVSDIIR-----LRNKTLTE--DEIATILQSTLKGLEYLHFMRKI 146
Query: 830 HRDLKPQNILIAPPKRYLSLHASKNKFRVLISDFGLCKKLEIDESSFRTNNFNNPTGTSG 889
HRD+K NIL+ + ++DFG+ +L D + R N GT
Sbjct: 147 HRDIKAGNILL------------NTEGHAKLADFGVAGQL-TDTMAKR----NTVIGTPF 189
Query: 890 WRAPEII 896
W APE+I
Sbjct: 190 WMAPEVI 196
>Hs5453964 [T] KOG0583 Serine/threonine protein kinase
Length = 550
Score = 60.5 bits (145), Expect = 2e-08
Identities = 87/312 (27%), Positives = 130/312 (40%), Gaps = 72/312 (23%)
Query: 715 LGYGSSGTV-VFQGKFQNRPVAVK---RLLIDFYDIASK---EIQLLSESDDHPNVIRYY 767
LG G+ G V V + + VAVK R I D+ K EIQ L + HP++I+ Y
Sbjct: 24 LGVGTFGKVKVGKHELTGHKVAVKILNRQKIRSLDVVGKIRREIQNL-KLFRHPHIIKLY 82
Query: 768 FSESTEKFMYIAVELCSASLEDVIEGSKGLAKNVAVQKNIDPINVLFQITSGVNHLHSMK 827
ST +++ +E S E + KN + + + + QI SGV++ H
Sbjct: 83 QVISTPSDIFMVMEYVSGG-----ELFDYICKNGRLDEK-ESRRLFQQILSGVDYCHRHM 136
Query: 828 IVHRDLKPQNILIAPPKRYLSLHASKNKFRVLISDFGLCKKLEIDESSFRTNNFNNPTGT 887
+VHRDLKP+N+L L H + I+DFGL + D RT+ G+
Sbjct: 137 VVHRDLKPENVL-------LDAHMNAK-----IADFGLSNMMS-DGEFLRTS-----CGS 178
Query: 888 SGWRAPEIISGEVSLSESFAXXXXXXXXXXXXXXLDVNHMDLVTKKRLTRAVDIFSLGCI 947
+ APE+ISG + VDI+S G I
Sbjct: 179 PNYAAPEVISGRLYAGPE---------------------------------VDIWSSGVI 205
Query: 948 FYYVLSKGEHPFGDRILREANILKGDYRLDGIKKSIQERSVCIEAADLIKSMLEQNPLLR 1007
Y +L G PF D + K DGI + Q + + L+K ML+ +P+ R
Sbjct: 206 LYALLC-GTLPFDDD--HVPTLFK--KICDGIFYTPQYLNPSV--ISLLKHMLQVDPMKR 258
Query: 1008 PASDEILKHPLF 1019
+ +I +H F
Sbjct: 259 ASIKDIREHEWF 270
>Hs5031689 [T] KOG4236 Serine/threonine protein kinase PKC mu/PKD and related
proteins
Length = 890
Score = 60.5 bits (145), Expect = 2e-08
Identities = 84/343 (24%), Positives = 140/343 (40%), Gaps = 73/343 (21%)
Query: 711 SSRVLGYGSSGTVVFQGKFQN--RPVAVKRLLIDFYDIASK-EIQLLSE-----SDDHPN 762
+ VLG G G +V+ GK + R VA+K +ID +K E QL +E + HP
Sbjct: 578 ADEVLGSGQFG-IVYGGKHRKTGRDVAIK--VIDKMRFPTKQESQLRNEVAILQNLHHPG 634
Query: 763 VIRYYFSESTEKFMYIAVELCSASLEDVIEGSKGLAKNVAVQKNIDPINVLFQITSGVNH 822
++ T + +++ +E + ++I S+ + K + + QI + +
Sbjct: 635 IVNLECMFETPERVFVVMEKLHGDMLEMILSSEKSRLPERITKFM-----VTQILVALRN 689
Query: 823 LHSMKIVHRDLKPQNILIAPPKRYLSLHASKNKFRVLISDFGLCKKLEIDESSFRTNNFN 882
LH IVH DLKP+N+L+A + + +V + DFG + I E SFR
Sbjct: 690 LHFKNIVHCDLKPENVLLASAEPFP---------QVKLCDFGFAR--IIGEKSFR----R 734
Query: 883 NPTGTSGWRAPEIISGEVSLSESFAXXXXXXXXXXXXXXLDVNHMDLVTKKRLTRAVDIF 942
+ GT + APE++ K R++D++
Sbjct: 735 SVVGTPAYLAPEVL----------------------------------RSKGYNRSLDMW 760
Query: 943 SLGCIFYYVLSKGEHPFGDRILREANILKGDYRLDGIKKSIQERSVCIEAADLIKSMLEQ 1002
S+G I Y LS G PF + + +I + R + EA DLI ++L+
Sbjct: 761 SVGVIIYVSLS-GTFPFNE----DEDINDQIQNAAFMYPPNPWREISGEAIDLINNLLQV 815
Query: 1003 NPLLRPASDEILKHPLFWGVSKKL---EFLLKVSDRFEVERRD 1042
R + D+ L HP L EF ++ +R+ D
Sbjct: 816 KMRKRYSVDKSLSHPWLQDYQTWLDLREFETRIGERYITHESD 858
>At2g30980 [G] KOG0658 Glycogen synthase kinase-3
Length = 412
Score = 60.5 bits (145), Expect = 2e-08
Identities = 88/344 (25%), Positives = 141/344 (40%), Gaps = 94/344 (27%)
Query: 710 ISSRVLGYGSSGTVVFQGKF--QNRPVAVKRLLIDFYDIASKEIQLLSESDDHPNVIRY- 766
++ RV+G GS G +VFQ K VA+K++L D ++E+QL+ D HPNV+
Sbjct: 73 MAERVVGTGSFG-IVFQAKCLETGESVAIKKVLQD-RRYKNRELQLMRLMD-HPNVVSLK 129
Query: 767 --YFSEST--EKFMYIAVELCSASLEDVIEGSKGLAKNVAVQKNIDPINVL----FQITS 818
+FS +T E F+ + +E +L V+ K+ PI + +QI
Sbjct: 130 HCFFSTTTRDELFLNLVMEYVPETLYRVL-------KHYTSSNQRMPIFYVKLYTYQIFR 182
Query: 819 GVNHLHSMK-IVHRDLKPQNILIAPPKRYLSLHASKNKFRVLISDFGLCKKLEIDESSFR 877
G+ ++H+ + HRD+KPQN+L+ P H K + DFG K L E++
Sbjct: 183 GLAYIHTAPGVCHRDVKPQNLLVDP-----LTHQCK------LCDFGSAKVLVKGEANI- 230
Query: 878 TNNFNNPTGTSGWRAPEIISGEVSLSESFAXXXXXXXXXXXXXXLDVNHMDLVTKKRLTR 937
+ + +RAPE+I G T
Sbjct: 231 -----SYICSRYYRAPELIFGAT---------------------------------EYTS 252
Query: 938 AVDIFSLGCIFYYV-----LSKGEHPFGDRI-------------LREANILKGDYRLDGI 979
++DI+S GC+ + L GE+ + +R N D+R I
Sbjct: 253 SIDIWSAGCVLAELLLGQPLFPGENSVDQLVEIIKVLGTPTREEIRCMNPNYTDFRFPQI 312
Query: 980 K----KSIQERSVCIEAADLIKSMLEQNPLLRPASDEILKHPLF 1019
K + + + EA DL +L+ +P LR + E HP F
Sbjct: 313 KAHPWHKVFHKRMPPEAIDLASRLLQYSPSLRCTALEACAHPFF 356
>7300149 [T] KOG0578 p21-activated serine/threonine protein kinase
Length = 569
Score = 60.5 bits (145), Expect = 2e-08
Identities = 80/341 (23%), Positives = 139/341 (40%), Gaps = 76/341 (22%)
Query: 711 SSRVLGYGSSGTVVFQGKFQNRP-VAVKRLLIDFYDIASKEIQLLS----ESDDHPNVIR 765
+++ +G G+SG V QN VAVK ID + +SK++ L + +H N++
Sbjct: 295 TTQEVGKGASGIVFIAADLQNESQVAVKT--IDMKNQSSKDLILTEIRVLKDFNHKNLVN 352
Query: 766 Y---YFSESTEKFMYIAVELCSASLEDVIEGSKGLAKNVAVQKNIDPINVLFQITSGVNH 822
+ Y E ++ + + L DV+ + + +A V + ++
Sbjct: 353 FLDAYLLEPEDQLWVVMEYMDGGPLTDVVTETVMKERQIAC--------VCRETLYAISF 404
Query: 823 LHSMKIVHRDLKPQNILIAPPKRYLSLHASKNKFRVLISDFGLCKKLEIDESSFRTNNFN 882
LH+ I+HRD+K N+L L + S V ++DFG C +E DE
Sbjct: 405 LHAKGIIHRDIKSDNVL-------LGMDGS-----VKVTDFGFCANIEGDEKR------Q 446
Query: 883 NPTGTSGWRAPEIISGEVSLSESFAXXXXXXXXXXXXXXLDVNHMDLVTKKRLTRAVDIF 942
GT W APE+ VT+K+ + VDI+
Sbjct: 447 TMVGTPYWMAPEV----------------------------------VTRKKYGKKVDIW 472
Query: 943 SLGCIFYYVLSKGEHPF-GDRILREANILKGDYRLDGIKKSIQERSVCIEAADLIKSMLE 1001
S+G I + +G+ P+ + LR ++ + R D KS + S ++ D + L+
Sbjct: 473 SIG-IMAIEMIEGQPPYLYETPLRALYLIAANGRPD--IKSWDKLSPNLQ--DFLDRCLQ 527
Query: 1002 QNPLLRPASDEILKHPLFWGVSKKLEFLLKVSDRFEVERRD 1042
R +DE+L HP S+ + + +V RR+
Sbjct: 528 VEVDRRATADELLSHPFLNDCSEVKALVPNIKAAKKVLRRN 568
>7293496 [R] KOG0597 Serine-threonine protein kinase FUSED
Length = 805
Score = 60.5 bits (145), Expect = 2e-08
Identities = 76/318 (23%), Positives = 134/318 (41%), Gaps = 76/318 (23%)
Query: 712 SRVLGYGSSGTVV-FQGKFQNRPVAVKRLLIDFYDIASKEIQLLSESDD------HPNVI 764
S ++G GS G V K ++ VA+K +I A+KE++ L D HP+VI
Sbjct: 7 SSMVGQGSFGCVYKATRKDDSKVVAIK--VISKRGRATKELKNLRRECDIQARLKHPHVI 64
Query: 765 RYYFSESTEKFMYIAVELCSASLEDVIEGSKGLAKNVAVQKNIDPINVLFQITSGVNHLH 824
S ++ +++ E L + + + + A + V + S + +LH
Sbjct: 65 EMIESFESKTDLFVVTEFALMDLHRYLSYNGAMGEEPARR-------VTGHLVSALYYLH 117
Query: 825 SMKIVHRDLKPQNILIAPPKRYLSLHASKNKFRVLISDFGLCKKLEIDESSFRTNNFNNP 884
S +I+HRDLKPQN+L+ ++HA + DFGL + + + T+ +
Sbjct: 118 SNRILHRDLKPQNVLLDK-----NMHAK-------LCDFGLARNMTLG-----THVLTSI 160
Query: 885 TGTSGWRAPEIISGEVSLSESFAXXXXXXXXXXXXXXLDVNHMDLVTKKRLTRAVDIFSL 944
GT + APE L+ ++ D++SL
Sbjct: 161 KGTPLYMAPE----------------------------------LLAEQPYDHHADMWSL 186
Query: 945 GCIFYYVLSKGEHPF-GDRILREANILKGDYRLDGIKKSIQERSVCIEAADLIKSMLEQN 1003
GCI Y ++ G+ PF IL ++K + +K ++ E ++ +LE++
Sbjct: 187 GCIAYESMA-GQPPFCASSILHLVKMIKH----EDVK---WPSTLTSECRSFLQGLLEKD 238
Query: 1004 PLLRPASDEILKHPLFWG 1021
P LR + ++L HP G
Sbjct: 239 PGLRISWTQLLCHPFVEG 256
>Hs4507719 [D] KOG0596 Dual specificity; serine/threonine and tyrosine kinase
Length = 841
Score = 60.1 bits (144), Expect = 2e-08
Identities = 73/314 (23%), Positives = 135/314 (42%), Gaps = 67/314 (21%)
Query: 711 SSRVLGYGSSGTVVFQGKFQNRPVAVKRLLIDFYDIASKEIQLLSESDDHPN-VIRYYFS 769
SS+V + ++ K+ N A + L D EI L++ H + +IR Y
Sbjct: 520 SSKVFQVLNEKKQIYAIKYVNLEEADNQTL----DSYRNEIAYLNKLQQHSDKIIRLYDY 575
Query: 770 ESTEKFMYIAVELCSASLEDVIEGSKGLAKNVAVQKNIDPI---NVLFQITSGVNHLHSM 826
E T++++Y+ +E + L ++ +K+IDP + + V+ +H
Sbjct: 576 EITDQYIYMVMECGNIDLNSWLKK----------KKSIDPWERKSYWKNMLEAVHTIHQH 625
Query: 827 KIVHRDLKPQNILIAPPKRYLSLHASKNKFRVLISDFGLCKKLEIDESSFRTNNFNNPTG 886
IVH DLKP N LI + + DFG+ +++ D +S ++ G
Sbjct: 626 GIVHSDLKPANFLIVDG-------------MLKLIDFGIANQMQPDTTSVVK---DSQVG 669
Query: 887 TSGWRAPEIISGEVSLSESFAXXXXXXXXXXXXXXLDVNHMDLVTKKRLTRAVDIFSLGC 946
T + PE I S E+ +K +++ D++SLGC
Sbjct: 670 TVNYMPPEAIKDMSSSRENGK-----------------------SKSKISPKSDVWSLGC 706
Query: 947 IFYYVLSKGEHPFG---DRILREANILKGDYRLDGIKKSIQERSVCIEAADLIKSMLEQN 1003
I YY ++ G+ PF ++I + I+ ++ ++ I E+ + D++K L+++
Sbjct: 707 ILYY-MTYGKTPFQQIINQISKLHAIIDPNHEIE--FPDIPEK----DLQDVLKCCLKRD 759
Query: 1004 PLLRPASDEILKHP 1017
P R + E+L HP
Sbjct: 760 PKQRISIPELLAHP 773
>Hs4502803 [D] KOG0590 Checkpoint kinase and related serine/threonine protein
kinases
Length = 476
Score = 60.1 bits (144), Expect = 2e-08
Identities = 56/194 (28%), Positives = 87/194 (43%), Gaps = 37/194 (19%)
Query: 713 RVLGYGSSGTVVFQ-GKFQNRPVAVK----RLLIDFYDIASKEIQLLSESDDHPNVIRYY 767
+ LG G+ G V + VAVK + +D + KEI +++ +H NV+++Y
Sbjct: 13 QTLGEGAYGEVQLAVNRVTEEAVAVKIVDMKRAVDCPENIKKEI-CINKMLNHENVVKFY 71
Query: 768 FSESTEKFMYIAVELCSAS-LEDVIEGSKGLAKNVAVQKNIDPINVLFQITSGVNHLHSM 826
Y+ +E CS L D IE G+ + D Q+ +GV +LH +
Sbjct: 72 GHRREGNIQYLFLEYCSGGELFDRIEPDIGMPEP-------DAQRFFHQLMAGVVYLHGI 124
Query: 827 KIVHRDLKPQNILIAPPKRYLSLHASKNKFRVLISDFGLCKKLEIDESSFRTNN----FN 882
I HRD+KP+N+L+ + + ISDFGL + FR NN N
Sbjct: 125 GITHRDIKPENLLL------------DERDNLKISDFGLA-------TVFRYNNRERLLN 165
Query: 883 NPTGTSGWRAPEII 896
GT + APE++
Sbjct: 166 KMCGTLPYVAPELL 179
>Hs20547712 [D] KOG0596 Dual specificity; serine/threonine and tyrosine kinase
Length = 841
Score = 60.1 bits (144), Expect = 2e-08
Identities = 73/314 (23%), Positives = 135/314 (42%), Gaps = 67/314 (21%)
Query: 711 SSRVLGYGSSGTVVFQGKFQNRPVAVKRLLIDFYDIASKEIQLLSESDDHPN-VIRYYFS 769
SS+V + ++ K+ N A + L D EI L++ H + +IR Y
Sbjct: 520 SSKVFQVLNEKKQIYAIKYVNLEEADNQTL----DSYRNEIAYLNKLQQHSDKIIRLYDY 575
Query: 770 ESTEKFMYIAVELCSASLEDVIEGSKGLAKNVAVQKNIDPI---NVLFQITSGVNHLHSM 826
E T++++Y+ +E + L ++ +K+IDP + + V+ +H
Sbjct: 576 EITDQYIYMVMECGNIDLNSWLKK----------KKSIDPWERKSYWKNMLEAVHTIHQH 625
Query: 827 KIVHRDLKPQNILIAPPKRYLSLHASKNKFRVLISDFGLCKKLEIDESSFRTNNFNNPTG 886
IVH DLKP N LI + + DFG+ +++ D +S ++ G
Sbjct: 626 GIVHSDLKPANFLIVDG-------------MLKLIDFGIANQMQPDTTSVVK---DSQVG 669
Query: 887 TSGWRAPEIISGEVSLSESFAXXXXXXXXXXXXXXLDVNHMDLVTKKRLTRAVDIFSLGC 946
T + PE I S E+ +K +++ D++SLGC
Sbjct: 670 TVNYMPPEAIKDMSSSRENGK-----------------------SKSKISPKSDVWSLGC 706
Query: 947 IFYYVLSKGEHPFG---DRILREANILKGDYRLDGIKKSIQERSVCIEAADLIKSMLEQN 1003
I YY ++ G+ PF ++I + I+ ++ ++ I E+ + D++K L+++
Sbjct: 707 ILYY-MTYGKTPFQQIINQISKLHAIIDPNHEIE--FPDIPEK----DLQDVLKCCLKRD 759
Query: 1004 PLLRPASDEILKHP 1017
P R + E+L HP
Sbjct: 760 PKQRISIPELLAHP 773
>CE28571 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 706
Score = 60.1 bits (144), Expect = 2e-08
Identities = 55/193 (28%), Positives = 83/193 (42%), Gaps = 27/193 (13%)
Query: 715 LGYGSSGTVVFQGKFQNRPVAVKRLLIDFYDIASK---EIQLLSESDDHPNVIRYYFSES 771
+G G G V + VA+KR ID ++ EIQ + E V+ +Y
Sbjct: 19 IGKGGFGVVYAAQRENGEKVAIKR--IDKKVPKNRVWTEIQTMKELKKSKYVVEFYEDFV 76
Query: 772 TEKFMYIAVELCSA-SLEDVIEGSKGLAKNVAVQKNIDPINVLFQITSGVNHLHSMKIVH 830
+ + YI +ELC SL+ + L AV +VL Q+ S V+ +H + ++H
Sbjct: 77 EDGYTYIVMELCEGGSLQAYVREHGALDDATAV-------HVLRQLISAVSFMHRVNVIH 129
Query: 831 RDLKPQNILIAPPKRYLSLHASKNKFRVLISDFGLCKKLEIDESSFRTNNFNNPTGTSGW 890
RDL N+ I K K K V + DFGL L E++ GT G+
Sbjct: 130 RDLSAGNVFIKDSK--------KKKMTVKLGDFGLATTLGRGETTCTI------VGTPGF 175
Query: 891 RAPEIISGEVSLS 903
AP++ E + S
Sbjct: 176 IAPQVYDQEYTQS 188
>CE01761 [R] KOG0663 Protein kinase PITSLRE and related kinases
Length = 719
Score = 60.1 bits (144), Expect = 2e-08
Identities = 49/185 (26%), Positives = 92/185 (49%), Gaps = 29/185 (15%)
Query: 723 VVFQGKFQNRP--VAVKRLLID-----FYDIASKEIQLLSESDDHPNVI--RYYFSESTE 773
VV++GK + VA+KRL ++ F A +EI +L ++ +HPN++ + S
Sbjct: 369 VVYRGKDKRTDEIVALKRLKMEKEKEGFPITALREINMLLKAGNHPNIVNVKEILLGSNM 428
Query: 774 KFMYIAVELCSASLEDVIEGSKGLAKNVAVQKNIDPINVLFQITSGVNHLHSMKIVHRDL 833
+Y+A+E ++ +++ K ++ + +L Q+ SG+ H+H + I+HRDL
Sbjct: 429 DKIYMAMEFVEHDMKSLLDTMSRRNKRFSIGEQK---TLLQQLLSGIEHMHKLWILHRDL 485
Query: 834 KPQNILIAPPKRYLSLHASKNKFRVLISDFGLCKKLEIDESSFRTNNFNNPTGTSGWRAP 893
K N+L++ +K + I+DFGL + E F + T +R+P
Sbjct: 486 KTSNLLMS------------HKGILKIADFGLAR-----EYGDPLKKFTSIVVTLWYRSP 528
Query: 894 EIISG 898
E++ G
Sbjct: 529 ELLLG 533
>At4g13000 [R] KOG0610 Putative serine/threonine protein kinase
Length = 372
Score = 60.1 bits (144), Expect = 2e-08
Identities = 99/371 (26%), Positives = 143/371 (37%), Gaps = 99/371 (26%)
Query: 707 HLSISSRVLGYGSSGTVVFQGKFQNRPVAVKRLLI---------DFYDIASKEIQLLSES 757
HL I S LG GS G VVF K N+ +A+K +L D Y S E +LS
Sbjct: 19 HLEIFS-ALGRGSKG-VVFLVKADNKWLALKVILRESIESKKAKDEYKRISFEQGVLSRF 76
Query: 758 DDHPNVIRYYFSESTEKFMYIAVELCSASLEDVIEGSKGLAKNVAVQKNIDPINVLF--Q 815
D HP R + ST+K + A++ C L K + + D I + +
Sbjct: 77 D-HPLFPRLHGVISTDKVIGYAIDYCPG------RDLNSLRKKQSEEMFSDEIIRFYAAE 129
Query: 816 ITSGVNHLHSMKIVHRDLKPQNILIA----------------PPKRYLS-------LHAS 852
+ + +LH+ IV+RDLKP N++I PP+ S L +
Sbjct: 130 LVIALEYLHNQGIVYRDLKPDNVMIQENGHLMLVDFDLSTNLPPRTPQSSFSSSPRLSTA 189
Query: 853 KNKFRVLISDFGLCKK--------LEIDESSFRTNNFNNPTGTSGWRAPEIISGEVSLSE 904
K R + + GLC ES F N+ GT + APE+I+G
Sbjct: 190 TKKERSIFAFSGLCNSGISPDDSVSRSSESEFSGEKSNSFVGTEEYVAPEVITGS---GH 246
Query: 905 SFAXXXXXXXXXXXXXXLDVNHMDLVTKKRLTRAVDIFSLGCIFYYVLSKGEHPFGDRIL 964
FA VD +SLG + Y +L G PF
Sbjct: 247 DFA-------------------------------VDWWSLGVVLYEMLY-GATPFRGSNR 274
Query: 965 REA--NILKGDYRLDGIKKSIQERSVCIEAADLIKSMLEQNPLLRPASDEILKHPLFWGV 1022
+E IL L G S++ DL++ +LE++P R + I H F G+
Sbjct: 275 KETFLKILTEPPSLVGETTSLR---------DLVRKLLEKDPSRRINVEGIKGHDFFKGL 325
Query: 1023 SKKLEFLLKVS 1033
+ +LKVS
Sbjct: 326 D--WDLVLKVS 334
>At4g09570 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-Hand protein
superfamily
Length = 501
Score = 60.1 bits (144), Expect = 2e-08
Identities = 78/288 (27%), Positives = 121/288 (41%), Gaps = 71/288 (24%)
Query: 737 KRLLI--DFYDIASKEIQLLSESDDHPNVIRYYFSESTEKFMYIAVELC-SASLEDVIEG 793
KR L+ + Y+ +EIQ++ +HPNV+R + F++I +E+C L D I
Sbjct: 58 KRKLVCREDYEDVWREIQIMHHLSEHPNVVRIKGTYEDSVFVHIVMEVCEGGELFDRIV- 116
Query: 794 SKGLAKNVAVQKNIDPINVLFQITSGVNHLHSMKIVHRDLKPQNILIAPPKRYLSLHASK 853
SKG K ++ I V HS+ ++HRDLKP+N L P L A
Sbjct: 117 SKGCFSEREAAK------LIKTILGVVEACHSLGVMHRDLKPENFLFDSPSDDAKLKA-- 168
Query: 854 NKFRVLISDFGLCKKLEIDESSFRTNNFNNPTGTSGWRAPEIISGEVSLSESFAXXXXXX 913
+DFGL + + + + G+ + APE++
Sbjct: 169 -------TDFGLSVFYKPGQYLY------DVVGSPYYVAPEVL----------------- 198
Query: 914 XXXXXXXXLDVNHMDLVTKKRLTRAVDIFSLGCIFYYVLSKGEHPF----GDRILREANI 969
KK +D++S G I Y +LS G PF I R+ I
Sbjct: 199 ------------------KKCYGPEIDVWSAGVILYILLS-GVPPFWAETESGIFRQ--I 237
Query: 970 LKGDYRLDGIKKSIQERSVCIEAADLIKSMLEQNPLLRPASDEILKHP 1017
L+G ++D KS ++ A DLI ML+++P R ++ E L HP
Sbjct: 238 LQG--KID--FKSDPWPTISEGAKDLIYKMLDRSPKKRISAHEALCHP 281
>Hs4502709 [R] KOG0594 Protein kinase PCTAIRE and related kinases
Length = 297
Score = 59.7 bits (143), Expect = 3e-08
Identities = 52/197 (26%), Positives = 95/197 (47%), Gaps = 32/197 (16%)
Query: 715 LGYGSSGTVVFQGKFQN--RPVAVKRLLIDFYD-----IASKEIQLLSESDDHPNVIRYY 767
+G G+ G VV++G+ + + VA+K++ ++ + A +EI LL E HPN++
Sbjct: 10 IGEGTYG-VVYKGRHKTTGQVVAMKKIRLESEEEGVPSTAIREISLLKELR-HPNIVSLQ 67
Query: 768 FSESTEKFMYIAVELCSASLEDVIEG-SKGLAKNVAVQKNIDPINVLFQITSGVNHLHSM 826
+ +Y+ E S L+ ++ G + ++ K+ L+QI G+ HS
Sbjct: 68 DVLMQDSRLYLIFEFLSMDLKKYLDSIPPGQYMDSSLVKSY-----LYQILQGIVFCHSR 122
Query: 827 KIVHRDLKPQNILIAPPKRYLSLHASKNKFRVLISDFGLCKKLEIDESSFRTNNFNNPTG 886
+++HRDLKPQN+LI +K + ++DFGL + I + +
Sbjct: 123 RVLHRDLKPQNLLI------------DDKGTIKLADFGLARAFGIP-----IRVYTHEVV 165
Query: 887 TSGWRAPEIISGEVSLS 903
T +R+PE++ G S
Sbjct: 166 TLWYRSPEVLLGSARYS 182
>Hs14196445 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-Hand protein
superfamily
Length = 476
Score = 59.7 bits (143), Expect = 3e-08
Identities = 68/261 (26%), Positives = 109/261 (41%), Gaps = 65/261 (24%)
Query: 760 HPNVIRYYFSESTEKFMYIAVELCSAS-LEDVIEGSKGLAKNVAVQKNIDPINVLFQITS 818
H N++ + Y+ ++L S L D I L + V +K D V+ Q+ S
Sbjct: 77 HENIVTLEDIYESTTHYYLVMQLVSGGELFDRI-----LERGVYTEK--DASLVIQQVLS 129
Query: 819 GVNHLHSMKIVHRDLKPQNILIAPPKRYLSLHASKNKFRVLISDFGLCKKLEIDESSFRT 878
V +LH IVHRDLKP+N+L P + +++I+DFGL K+E +
Sbjct: 130 AVKYLHENGIVHRDLKPENLLYLTP---------EENSKIMITDFGL-SKME------QN 173
Query: 879 NNFNNPTGTSGWRAPEIISGEVSLSESFAXXXXXXXXXXXXXXLDVNHMDLVTKKRLTRA 938
+ GT G+ APE+++ +K ++A
Sbjct: 174 GIMSTACGTPGYVAPEVLA----------------------------------QKPYSKA 199
Query: 939 VDIFSLGCIFYYVLSKGEHPFGDRILRE--ANILKGDYRLDGIKKSIQERSVCIEAADLI 996
VD +S+G I Y +L G PF + + I +G Y + S + A D I
Sbjct: 200 VDCWSIGVITYILLC-GYPPFYEETESKLFEKIKEGYYEFE----SPFWDDISESAKDFI 254
Query: 997 KSMLEQNPLLRPASDEILKHP 1017
+LE++P R ++ L HP
Sbjct: 255 CHLLEKDPNERYTCEKALSHP 275
>ECU08g0230 [R] KOG0594 Protein kinase PCTAIRE and related kinases
Length = 265
Score = 59.7 bits (143), Expect = 3e-08
Identities = 77/316 (24%), Positives = 134/316 (42%), Gaps = 74/316 (23%)
Query: 710 ISSRVLGYGSSGTVVFQGKFQNRP-VAVKRLLIDFYD----IASKEIQLLSESDDHPNVI 764
I ++G G+ G V + + VA+KR+ ++ + A +EI +L + H N+I
Sbjct: 5 ILGALIGSGTYGEVYEAIDTETKEKVALKRIRLNEKEGMPGTALREISILKKLS-HRNII 63
Query: 765 RYYFSESTEKFMYIAVELCSASLEDVIEGSKGLAKNVAVQKNIDPINVLFQITSGVNHLH 824
T+ + + L+ I + G KNI + ++ Q+ GV++LH
Sbjct: 64 SLVSIIHTDALLTMVFPFIDYELKKYIGMNTG--------KNI--MELVNQLICGVHYLH 113
Query: 825 SMKIVHRDLKPQNILIAPPKRYLSLHASKNKFRVLISDFGLCKKLEIDESSFRTNNFNNP 884
M +VHRDLKPQNIL+ + + I+DFGL + LEI R +++
Sbjct: 114 RMNVVHRDLKPQNILVT------------SDGVLKIADFGLSRSLEI-----RVPPYSSE 156
Query: 885 TGTSGWRAPEIISGEVSLSESFAXXXXXXXXXXXXXXLDVNHMDLVTKKRLTRAVDIFSL 944
T +R+PE++ G S VDI+SL
Sbjct: 157 VVTLWYRSPELLMGSTS---------------------------------YRFYVDIWSL 183
Query: 945 GCIFYYVLSKGEHPFGDRILREANILKGDYRLDGIKKSI-----QERSVCIEAADLIKSM 999
GCI Y +++ G+ + +++ R G ++S+ Q +V ++I
Sbjct: 184 GCIIYEMITLEPLFPGESKENQLTLIR---RKAGTRRSLRGMVEQRLAVPKFVTEIIVRC 240
Query: 1000 LEQNPLLRPASDEILK 1015
L+ N R +DEI++
Sbjct: 241 LDFNYNQRITADEIME 256
>CE29073 [R] KOG0594 Protein kinase PCTAIRE and related kinases
Length = 700
Score = 59.7 bits (143), Expect = 3e-08
Identities = 52/195 (26%), Positives = 92/195 (46%), Gaps = 31/195 (15%)
Query: 715 LGYGSSGTVVFQGK--FQNRPVAVKRLLIDFYD----IASKEIQLLSESDDHPNVIRYYF 768
LG G+ TV F+G+ N+ VA+K + ++ + A +E+ LL H NV+ +
Sbjct: 367 LGEGTYATV-FRGRSILTNKFVALKEIRLEQEEGAPCTAIREVSLLRNLR-HANVVTLHD 424
Query: 769 SESTEKFMYIAVELCSASLEDVIEGSKGLAKNVAVQKNIDPINVLFQITSGVNHLHSMKI 828
T++ + + E L+ ++ N A+Q N + L+Q+ G+ + H ++
Sbjct: 425 IIHTDRLLTLVFEYVDRDLKQYMDSC-----NNAMQMNNIRL-FLYQLLRGLAYCHQRRV 478
Query: 829 VHRDLKPQNILIAPPKRYLSLHASKNKFRVLISDFGLCKKLEIDESSFRTNNFNNPTGTS 888
+HRDLKPQN+LI K + ++DFGL + S T ++N T
Sbjct: 479 LHRDLKPQNLLITA------------KGELKLADFGLAR-----AKSVPTKTYSNEVVTL 521
Query: 889 GWRAPEIISGEVSLS 903
+R P+++ G S
Sbjct: 522 WYRPPDVLLGSTDYS 536
>CE06779 [R] KOG0594 Protein kinase PCTAIRE and related kinases
Length = 577
Score = 59.7 bits (143), Expect = 3e-08
Identities = 52/195 (26%), Positives = 92/195 (46%), Gaps = 31/195 (15%)
Query: 715 LGYGSSGTVVFQGK--FQNRPVAVKRLLIDFYD----IASKEIQLLSESDDHPNVIRYYF 768
LG G+ TV F+G+ N+ VA+K + ++ + A +E+ LL H NV+ +
Sbjct: 244 LGEGTYATV-FRGRSILTNKFVALKEIRLEQEEGAPCTAIREVSLLRNLR-HANVVTLHD 301
Query: 769 SESTEKFMYIAVELCSASLEDVIEGSKGLAKNVAVQKNIDPINVLFQITSGVNHLHSMKI 828
T++ + + E L+ ++ N A+Q N + L+Q+ G+ + H ++
Sbjct: 302 IIHTDRLLTLVFEYVDRDLKQYMDSC-----NNAMQMNNIRL-FLYQLLRGLAYCHQRRV 355
Query: 829 VHRDLKPQNILIAPPKRYLSLHASKNKFRVLISDFGLCKKLEIDESSFRTNNFNNPTGTS 888
+HRDLKPQN+LI K + ++DFGL + S T ++N T
Sbjct: 356 LHRDLKPQNLLITA------------KGELKLADFGLAR-----AKSVPTKTYSNEVVTL 398
Query: 889 GWRAPEIISGEVSLS 903
+R P+++ G S
Sbjct: 399 WYRPPDVLLGSTDYS 413
>At5g18500 [T] KOG1187 Serine/threonine protein kinase
Length = 484
Score = 59.7 bits (143), Expect = 3e-08
Identities = 92/357 (25%), Positives = 148/357 (40%), Gaps = 66/357 (18%)
Query: 565 IIRIVESGLMMVLAVFLLYIL-------ASLNVIPPLHVLLTEIGILPKVQIPTQEVKID 617
II IV S + +V+ L++ +S N+IP I P V +E+++D
Sbjct: 21 IIVIVLSAIFVVVLAISLWLTFRRKTSRSSSNLIP------VSRQIPPSVPEEIKEIRVD 74
Query: 618 TAISHKVNTNDIGKELSEKNTGNQDLPFDQNEGVSSETGTGDFEAXXXXXXXXXXXXXXX 677
S N + +SEK G+++ +G+ +E+ GD
Sbjct: 75 EVSSS--NGGNGYPSISEK-FGDKE----PEKGIKAESENGD----SSRSGSFNHLEKKD 123
Query: 678 XXXXXXXXXLDDDGPMLDFKEFEQEGH-----LKHLSISSR------VLGYGSSGTVVFQ 726
L P+ EF G L+ L +++ ++G G G VV++
Sbjct: 124 GSSVSSANPLTAPSPLSGLPEFSHLGWGHWFTLRDLQMATNQFSRDNIIGDGGYG-VVYR 182
Query: 727 GKFQN-RPVAVKRLLIDFYDIASKEIQLLSESDDH---PNVIRY--YFSESTEKFMYIAV 780
G N PVAVK+LL + A K+ ++ E+ H N++R Y E T++ M +
Sbjct: 183 GNLVNGTPVAVKKLLNNLGQ-ADKDFRVEVEAIGHVRHKNLVRLLGYCMEGTQR-MLVYE 240
Query: 781 ELCSASLEDVIEGSKGLAKNVAVQKNIDPINVLFQITSGVNHLHSM---KIVHRDLKPQN 837
+ + +LE + G + + + + +L + +LH K+VHRD+K N
Sbjct: 241 YVNNGNLEQWLRGDNQNHEYLTWEARV---KILIGTAKALAYLHEAIEPKVVHRDIKSSN 297
Query: 838 ILIAPPKRYLSLHASKNKFRVLISDFGLCKKLEIDESSFRTNNFNNPTGTSGWRAPE 894
ILI +KF ISDFGL K L D+S T GT G+ APE
Sbjct: 298 ILI------------DDKFNSKISDFGLAKLLGADKSFITT----RVMGTFGYVAPE 338
>At3g06030 [T] KOG0198 MEKK and related serine/threonine protein kinases
Length = 651
Score = 59.7 bits (143), Expect = 3e-08
Identities = 66/278 (23%), Positives = 114/278 (40%), Gaps = 70/278 (25%)
Query: 749 KEIQLLSESDDHPNVIRYYFSESTEKFMYIAVELC-SASLEDVIEGSKGLAKNVAVQKNI 807
+E+QLL HPN++RY + + I +E S+ ++E
Sbjct: 120 EEVQLLKNLS-HPNIVRYLGTVRESDSLNILMEFVPGGSISSLLEKFGSFP--------- 169
Query: 808 DPINVLF--QITSGVNHLHSMKIVHRDLKPQNILIAPPKRYLSLHASKNKFRVLISDFGL 865
+P+ +++ Q+ G+ +LH+ I+HRD+K NIL+ NK + ++DFG
Sbjct: 170 EPVIIMYTKQLLLGLEYLHNNGIMHRDIKGANILV------------DNKGCIRLADFGA 217
Query: 866 CKKLEIDESSFRTNNFNNPTGTSGWRAPEIISGEVSLSESFAXXXXXXXXXXXXXXLDVN 925
KK+ N + GT W APE+I L
Sbjct: 218 SKKV---VELATVNGAKSMKGTPYWMAPEVI-------------------------LQTG 249
Query: 926 HMDLVTKKRLTRAVDIFSLGCIFYYVLSKGEHPFGDRILREANILKGDYRLDGIKKSIQ- 984
H + + DI+S+GC ++ G+ P+ ++ + A +L G K+
Sbjct: 250 H---------SFSADIWSVGCT-VIEMATGKPPWSEQYQQFAAVLH-----IGRTKAHPP 294
Query: 985 -ERSVCIEAADLIKSMLEQNPLLRPASDEILKHPLFWG 1021
+ EA D + L + P LR ++ E+L+HP G
Sbjct: 295 IPEDLSPEAKDFLMKCLHKEPSLRLSATELLQHPFVTG 332
>At1g06390 [G] KOG0658 Glycogen synthase kinase-3
Length = 407
Score = 59.7 bits (143), Expect = 3e-08
Identities = 86/344 (25%), Positives = 141/344 (40%), Gaps = 94/344 (27%)
Query: 710 ISSRVLGYGSSGTVVFQGKF--QNRPVAVKRLLIDFYDIASKEIQLLSESDDHPNVIRY- 766
++ RV+G GS G +VFQ K VA+K++L D ++E+QL+ D HPNVI
Sbjct: 71 MAERVVGTGSFG-IVFQAKCLETGESVAIKKVLQD-RRYKNRELQLMRPMD-HPNVISLK 127
Query: 767 --YFSEST--EKFMYIAVELCSASLEDVIEGSKGLAKNVAVQKNIDPINVL----FQITS 818
+FS ++ E F+ + +E +L V+ ++ PI + +QI
Sbjct: 128 HCFFSTTSRDELFLNLVMEYVPETLYRVL-------RHYTSSNQRMPIFYVKLYTYQIFR 180
Query: 819 GVNHLHSMK-IVHRDLKPQNILIAPPKRYLSLHASKNKFRVLISDFGLCKKLEIDESSFR 877
G+ ++H++ + HRD+KPQN+L+ P +V + DFG K L E +
Sbjct: 181 GLAYIHTVPGVCHRDVKPQNLLVDPLTH-----------QVKLCDFGSAKVLVKGEPNI- 228
Query: 878 TNNFNNPTGTSGWRAPEIISGEVSLSESFAXXXXXXXXXXXXXXLDVNHMDLVTKKRLTR 937
+ + +RAPE+I G T
Sbjct: 229 -----SYICSRYYRAPELIFGAT---------------------------------EYTA 250
Query: 938 AVDIFSLGCIFYYV-----LSKGEHPFGDRI-------------LREANILKGDYRLDGI 979
++DI+S GC+ + L GE+ + +R N D+R I
Sbjct: 251 SIDIWSAGCVLAELLLGQPLFPGENSVDQLVEIIKVLGTPTREEIRCMNPNYTDFRFPQI 310
Query: 980 K----KSIQERSVCIEAADLIKSMLEQNPLLRPASDEILKHPLF 1019
K + + + EA DL +L+ +P LR + E HP F
Sbjct: 311 KAHPWHKVFHKRMPPEAIDLASRLLQYSPSLRCTALEACAHPFF 354
>7295585 [T] KOG0192 Tyrosine kinase specific for activated (GTP-bound)
p21cdc42Hs
Length = 678
Score = 59.7 bits (143), Expect = 3e-08
Identities = 57/190 (30%), Positives = 92/190 (48%), Gaps = 33/190 (17%)
Query: 715 LGYGSSGTVVFQGKFQNRPVAVKRLLI--DFYDIASKEIQLLSESDDHPNVIRYYFSEST 772
+G+GS G VV + ++++ VAVK + DI KE++ LS HPN+I + S
Sbjct: 25 VGHGSYG-VVCKAVWRDKLVAVKEFFASAEQKDI-EKEVKQLSRVK-HPNIIALHGISSY 81
Query: 773 EKFMYIAVELCSA-SLEDVIEGSKGLAKNVAVQKNIDPINVLFQITSGVNHLHSMK---I 828
++ Y+ +E SL + + G A ++A ++ Q G+ +LH+M +
Sbjct: 82 QQATYLIMEFAEGGSLHNFLHGKVKPAYSLA-----HAMSWARQCAEGLAYLHAMTPKPL 136
Query: 829 VHRDLKPQNILIAPPKRYLSLHASKNKFRVLISDFGLCKKLEIDESSFRTNNFNNPTGTS 888
+HRD+KP N+L+ R L I DFG D+S+ TNN G++
Sbjct: 137 IHRDVKPLNLLLTNKGRNLK-----------ICDFGTV----ADKSTMMTNN----RGSA 177
Query: 889 GWRAPEIISG 898
W APE+ G
Sbjct: 178 AWMAPEVFEG 187
>SPCC1259.13 [D] KOG0590 Checkpoint kinase and related serine/threonine protein
kinases
Length = 496
Score = 59.3 bits (142), Expect = 3e-08
Identities = 67/277 (24%), Positives = 107/277 (38%), Gaps = 72/277 (25%)
Query: 748 SKEIQLLSESDDHPNVIRYYFSESTEKFMYIAVELCSAS-LEDVIEGSKGLAKNVAVQKN 806
+ EIQL + H N+I +Y + ++ ++ +E L D IE G+ ++VA
Sbjct: 59 ASEIQLHKLCNGHKNIIHFYNTAENPQWRWVVLEFAQGGDLFDKIEPDVGIDEDVAQF-- 116
Query: 807 IDPINVLFQITSGVNHLHSMKIVHRDLKPQNILIAPPKRYLSLHASKNKFRVLISDFGLC 866
Q+ G++ +HS + HRDLKP+NIL+ + ISDFG
Sbjct: 117 -----YFAQLMEGISFMHSKGVAHRDLKPENILL------------DYNGNLKISDFGFA 159
Query: 867 KKLEIDESSFRTNNFNNPTGTSGWRAPEIISGEVSLSESFAXXXXXXXXXXXXXXLDVNH 926
S N+P G+ + APEI
Sbjct: 160 SLFSYKGKS---RLLNSPVGSPPYAAPEI------------------------------- 185
Query: 927 MDLVTKKRLTRAVDIFSLGCIFYYVLSKGEHPFGDRILREANILKGDYRLDGIKKSIQER 986
T++ VD++S G I + +L G P+ + I GDY L KK +
Sbjct: 186 ----TQQYDGSKVDVWSCGIILFALL-LGNTPWDEAISN-----TGDYLL--YKKQCERP 233
Query: 987 S------VCIEAADLIKSMLEQNPLLRPASDEILKHP 1017
S + A +I ML +P R + +++HP
Sbjct: 234 SYHPWNLLSPGAYSIITGMLRSDPFKRYSVKHVVQHP 270
>Hs4506739 [RT] KOG0598 Ribosomal protein S6 kinase and related proteins
Length = 495
Score = 59.3 bits (142), Expect = 3e-08
Identities = 92/362 (25%), Positives = 148/362 (40%), Gaps = 95/362 (26%)
Query: 713 RVLGYGSSGTVV----FQGKFQNRPVAVK-----RLLIDFYDIASKEIQL-LSESDDHPN 762
RVLG G G V QG + A+K +++ + D A + + ES HP
Sbjct: 84 RVLGKGGYGKVFQVRKVQGTNLGKIYAMKVLRKAKIVRNAKDTAHTRAERNILESVKHPF 143
Query: 763 VIRYYFSESTEKFMYIAVE-LCSASLEDVIEGSKGLAKNVAVQKNIDPINVLFQITSGVN 821
++ ++ T +Y+ +E L L +E ++ A L +IT +
Sbjct: 144 IVELAYAFQTGGKLYLILECLSGGELFTHLEREGIFLEDTACF-------YLAEITLALG 196
Query: 822 HLHSMKIVHRDLKPQNILIAPPKRYLSLHASKNKFRVLISDFGLCKKLEIDESSFRTNNF 881
HLHS I++RDLKP+NI+++ ++ + ++DFGLCK+ I E + T+ F
Sbjct: 197 HLHSQGIIYRDLKPENIMLS------------SQGHIKLTDFGLCKE-SIHEGAV-THTF 242
Query: 882 NNPTGTSGWRAPEIISGEVSLSESFAXXXXXXXXXXXXXXLDVNHMDLVTKKRLTRAVDI 941
GT + APEI+ + RAVD
Sbjct: 243 ---CGTIEYMAPEIL----------------------------------VRSGHNRAVDW 265
Query: 942 FSLGCIFYYVLSKGEHPF--GDRILREANILKGDYRLDGIKKSIQERSVCIEAADLIKSM 999
+SLG + Y +L+ G PF +R I++G L + +A DL+K
Sbjct: 266 WSLGALMYDMLT-GSPPFTAENRKKTMDKIIRGKLALPPY--------LTPDARDLVKKF 316
Query: 1000 LEQNPLLRPA-----SDEILKHPLFWGVSKKLEFLLKVSDRFEVERRDPP-SPLLLKLEE 1053
L++NP R + ++ +HP F ++ D R DPP P L E+
Sbjct: 317 LKRNPSQRIGGGPGDAADVQRHPFFRHMN---------WDDLLAWRVDPPFRPCLQSEED 367
Query: 1054 VS 1055
VS
Sbjct: 368 VS 369
>Hs4505649 [R] KOG0594 Protein kinase PCTAIRE and related kinases
Length = 523
Score = 59.3 bits (142), Expect = 3e-08
Identities = 49/189 (25%), Positives = 86/189 (44%), Gaps = 29/189 (15%)
Query: 715 LGYGSSGTVVF-QGKFQNRPVAVKRLLIDFYD----IASKEIQLLSESDDHPNVIRYYFS 769
LG G+ TV + K VA+K + ++ + A +E+ LL + H N++ +
Sbjct: 198 LGEGTYATVYKGRSKLTENLVALKEIRLEHEEGAPCTAIREVSLLKDLK-HANIVTLHDI 256
Query: 770 ESTEKFMYIAVELCSASLEDVIEGSKGLAKNVAVQKNIDPINVLFQITSGVNHLHSMKIV 829
T+K + + E L+ ++ N+ N+ L+QI G+ + H K++
Sbjct: 257 VHTDKSLTLVFEYLDKDLKQYMDD----CGNIMSMHNVKLF--LYQILRGLAYCHRRKVL 310
Query: 830 HRDLKPQNILIAPPKRYLSLHASKNKFRVLISDFGLCKKLEIDESSFRTNNFNNPTGTSG 889
HRDLKPQN+LI K + ++DFGL + S T ++N T
Sbjct: 311 HRDLKPQNLLI------------NEKGELKLADFGLAR-----AKSVPTKTYSNEVVTLW 353
Query: 890 WRAPEIISG 898
+R P+++ G
Sbjct: 354 YRPPDVLLG 362
>CE28740 [T] KOG0592 3-phosphoinositide-dependent protein kinase (PDK1)
Length = 636
Score = 59.3 bits (142), Expect = 3e-08
Identities = 54/213 (25%), Positives = 92/213 (42%), Gaps = 30/213 (14%)
Query: 815 QITSGVNHLHSMKIVHRDLKPQNILIAPPKRYLSLHASKNKFRVLISDFGLCKK---LEI 871
+I +G+ LH KIVHRD+KP N+LI + +LI+DFG + L++
Sbjct: 180 EILTGLQFLHDNKIVHRDMKPDNVLI------------QKDGHILITDFGSAQAFGGLQL 227
Query: 872 DESSFR-TNNFNNPTGTSGWRAPEIISGEVSLSESFAXXXXXXXXXXXXXXLDVNHMDLV 930
+ F N ++ + SG P + + E +++
Sbjct: 228 SQEGFTDANQASSRSSDSGSPPPTRFYSDEEVPEENTARRTTFVGTALYVS-----PEML 282
Query: 931 TKKRLTRAVDIFSLGCIFYYVLSKGEHPFGDRILREANILKGDYRLD-GIKKSIQERSVC 989
+ DI+ LGCI + L+ G+ PF R + + ++LK LD + E
Sbjct: 283 ADGDVGPQTDIWGLGCILFQCLA-GQPPF--RAVNQYHLLKRIQELDFSFPEGFPE---- 335
Query: 990 IEAADLIKSMLEQNPLLRPASDEILKHPLFWGV 1022
EA+++I +L ++P R S E++ H F V
Sbjct: 336 -EASEIIAKILVRDPSTRITSQELMAHKFFENV 367
>CE17284 [T] KOG0583 Serine/threonine protein kinase
Length = 726
Score = 59.3 bits (142), Expect = 3e-08
Identities = 55/191 (28%), Positives = 85/191 (43%), Gaps = 30/191 (15%)
Query: 715 LGYGSSGTV-VFQGKFQNRPVAVKRLLIDFYDIASKEIQLLSESD-----DHPNVIRYYF 768
LG G G V + N+ VA+K +ID + ++ +E D H N+ R Y
Sbjct: 17 LGSGGFGKVRLATHLLTNQKVAIK--IIDKKQLGHDLPRVQTEMDALRNLSHQNICRLYH 74
Query: 769 SESTEKFMYIAVELCSAS-LEDVIEGSKGLAKNVAVQKNIDPINVLFQITSGVNHLHSMK 827
TE +I +E CS + D I + L ++ A + Q+ S + +HS
Sbjct: 75 YIETEDKFFIVMEYCSGGEMFDYIVRKERLEESEAR-------HFFRQLVSAIAFVHSQG 127
Query: 828 IVHRDLKPQNILIAPPKRYLSLHASKNKFRVLISDFGLCKKLEIDESSFRTNNFNNPTGT 887
HRDLKP+N+L+ LH + + DFGLC K E + +N + G+
Sbjct: 128 YAHRDLKPENLLLTE-----DLH-------LKLIDFGLCAKTE--KGRIDKHNLDTCCGS 173
Query: 888 SGWRAPEIISG 898
+ APE+I G
Sbjct: 174 PAYAAPELIQG 184
>CE12478 [D] KOG0590 Checkpoint kinase and related serine/threonine protein
kinases
Length = 484
Score = 59.3 bits (142), Expect = 3e-08
Identities = 53/195 (27%), Positives = 87/195 (44%), Gaps = 31/195 (15%)
Query: 715 LGYGSSGTV--VFQGKFQNRPVAVKRLLI-----DFYDIASKEIQLLSESDDHPNVIRYY 767
LG GS G V V ++ A+KR++I ++ D KEI + H NVI+
Sbjct: 31 LGQGSFGQVALVSNRRYPEMLAALKRIVITGQDREYIDAIRKEITIQESLTGHENVIQVL 90
Query: 768 FSESTEKFMYIAVELCSAS--LEDVIEGSKGLAKNVAVQKNIDPINVLF-QITSGVNHLH 824
ES +F Y+ +E E + G +++ + F Q+ +G+ LH
Sbjct: 91 GKESDAQFCYMFLEYADGGDLYEKITSGCSF---------SLEEAHSYFKQLVNGLKFLH 141
Query: 825 SMKIVHRDLKPQNILIAPPKRYLSLHASKNKFRVL-ISDFGLCKKLEIDESSFRTNNFNN 883
+ HRD+KP+N+++ H+ K++ R L I+DFGL + F
Sbjct: 142 CRDVAHRDIKPENLMLT--------HSGKSEMRHLKIADFGLATWYRYKGAEL---IFEQ 190
Query: 884 PTGTSGWRAPEIISG 898
G+ + APEI +G
Sbjct: 191 RCGSVEYVAPEIYTG 205
>At5g38260 [T] KOG1187 Serine/threonine protein kinase
Length = 638
Score = 59.3 bits (142), Expect = 3e-08
Identities = 61/215 (28%), Positives = 95/215 (43%), Gaps = 33/215 (15%)
Query: 693 MLDFKEFEQEGHLKHLSISSRVLGYGSSGTVVFQGKFQNRPVAVKRLLIDFYDIAS---K 749
++ K++ K + S LG G GTV R VAVK +L DF
Sbjct: 305 LVQLKQYSYAEVRKITKLFSHTLGKGGFGTVYGGNLCDGRKVAVK-ILKDFKSNGEDFIN 363
Query: 750 EIQLLSESDDHPNVIR---YYFSESTEKFMYIAVELCSASLEDVIEGSKGLAKNVAVQKN 806
E+ +S++ H N++ + + S +Y +E + SL+ + K L +V+
Sbjct: 364 EVASMSQTS-HVNIVSLLGFCYEGSKRAIVYEFLE--NGSLDQFLSEKKSLNLDVSTLYR 420
Query: 807 IDPINVLFQITSGVNHLH---SMKIVHRDLKPQNILIAPPKRYLSLHASKNKFRVLISDF 863
I + G+++LH +IVH D+KPQNIL+ + F +SDF
Sbjct: 421 I-----ALGVARGLDYLHHGCKTRIVHFDIKPQNILL------------DDTFCPKVSDF 463
Query: 864 GLCKKLEIDESSFRTNNFNNPTGTSGWRAPEIISG 898
GL K E ES + + GT G+ APE+ SG
Sbjct: 464 GLAKLCEKRESIL---SLLDARGTIGYIAPEVFSG 495
>At1g69220 [T] KOG0576 Mitogen-activated protein kinase kinase kinase kinase
(MAP4K) germinal center kinase family
Length = 836
Score = 59.3 bits (142), Expect = 3e-08
Identities = 53/188 (28%), Positives = 89/188 (47%), Gaps = 30/188 (15%)
Query: 715 LGYGSSGTVVFQGKFQNRP-VAVKRLLI----DFYDIASKEIQLLSESDDHPNVIRYYFS 769
LG GS G+V + VAVK + + + Y+ EI++L + + HPNV+RY S
Sbjct: 255 LGKGSYGSVYKARDLKTSEIVAVKVISLTEGEEGYEEIRGEIEMLQQCN-HPNVVRYLGS 313
Query: 770 ESTEKFMYIAVELC-SASLEDVIEGSKGLAKNVAVQKNIDPINVLFQITSGVNHLHSMKI 828
E +++I +E C S+ D++ ++ + + + + G+ +LHS+
Sbjct: 314 YQGEDYLWIVMEYCGGGSVADLMNVTEEALEEYQI------AYICREALKGLAYLHSIYK 367
Query: 829 VHRDLKPQNILIAPPKRYLSLHASKNKFRVLISDFGLCKKLEIDESSFRTNNFNNPTGTS 888
VHRD+K NIL+ + V + DFG+ +L + + N F GT
Sbjct: 368 VHRDIKGGNILLT------------EQGEVKLGDFGVAAQL--TRTMSKRNTF---IGTP 410
Query: 889 GWRAPEII 896
W APE+I
Sbjct: 411 HWMAPEVI 418
>7304283 [Z] KOG0613 Projectin/twitchin and related proteins
Length = 7175
Score = 59.3 bits (142), Expect = 3e-08
Identities = 65/281 (23%), Positives = 113/281 (40%), Gaps = 67/281 (23%)
Query: 745 DIASKEIQLLSESDDHPNVIRYYFSESTEKFMYIAVELCSASLEDVIEGSKGLAKNVAVQ 804
D+ +EI ++++ H +I + + + M + +E S E + + V
Sbjct: 6178 DLIRREIDIMNQLH-HQKLINLHDAFEDDDEMILILEFLSGG-----ELFERITAEGYVM 6231
Query: 805 KNIDPINVLFQITSGVNHLHSMKIVHRDLKPQNILIAPPKRYLSLHASKNKFRVLISDFG 864
+ IN + QI G+ H+H I+H D+KP+NI+ +++ V + DFG
Sbjct: 6232 TEAEVINYMRQICEGIRHMHEQNIIHLDIKPENIMC----------QTRSSTNVKLIDFG 6281
Query: 865 LCKKLEIDESSFRTNNFNNPTGTSGWRAPEIISGEVSLSESFAXXXXXXXXXXXXXXLDV 924
L +L+ +E T TGT+ + APEI
Sbjct: 6282 LATRLDPNEVVKIT------TGTAEFAAPEI----------------------------- 6306
Query: 925 NHMDLVTKKRLTRAVDIFSLGCIFYYVLSKGEHPF-GD---RILREANILKGDYRLDGIK 980
V ++ + D+++ G + YVL G PF GD + L+ D+ ++ K
Sbjct: 6307 -----VNREPVGFYTDMWATG-VLSYVLLSGLSPFAGDNDVQTLKNVKACDWDFDVESFK 6360
Query: 981 KSIQERSVCIEAADLIKSMLEQNPLLRPASDEILKHPLFWG 1021
+ EA D I+ +L +N R + E L HP G
Sbjct: 6361 ------YISEEAKDFIRKLLVRNKEKRMTAHECLLHPWLTG 6395
>7301004 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 411
Score = 59.3 bits (142), Expect = 3e-08
Identities = 37/148 (25%), Positives = 73/148 (49%), Gaps = 20/148 (13%)
Query: 750 EIQLLSESDDHPNVIRYYFSESTEKFMYIAVELCSASLEDVIEGSKGLAKNVAVQKNIDP 809
E ++L + HPN+I ++ E++MY +E +++ VI+ +G+ D
Sbjct: 195 EAEVLRQLQSHPNIIELMYTVEDERYMYTVLEHLDCNMQKVIQ-KRGILSEA------DA 247
Query: 810 INVLFQITSGVNHLHSMKIVHRDLKPQNILIAPPKRYLSLHASKNKFRVLISDFGLCKKL 869
+V+ S + H+H ++++HRD+KP+N+L+ S N V +++F L
Sbjct: 248 RSVMRCTVSALAHMHQLQVIHRDIKPENLLVC------SSSGKWNFKMVKVANFDLA--- 298
Query: 870 EIDESSFRTNNFNNPTGTSGWRAPEIIS 897
+ +R + GT + APE+I+
Sbjct: 299 ----TYYRGSKLYVRCGTPCYMAPEMIA 322
>SPBC8D2.19 [T] KOG0661 MAPK related serine/threonine protein kinase
Length = 559
Score = 58.9 bits (141), Expect = 4e-08
Identities = 59/209 (28%), Positives = 92/209 (43%), Gaps = 40/209 (19%)
Query: 715 LGYGSSGTVVF-QGKFQN---RPVAVKRLLIDFYDIASKEIQLLSES------DDHPNVI 764
LG GS GTV Q K +N VAVK+L E+ L ES HP +I
Sbjct: 27 LGDGSFGTVYLAQRKEKNGLYETVAVKKLKNSSKPKPKHELLKLRESLALRKISKHPCLI 86
Query: 765 RYYFSESTEKFM------YIAVELCSASLEDVIEGSKG--LAKNVAVQKNIDPINVLFQI 816
+ E FM ++ +E +L + + +G K A N+L QI
Sbjct: 87 -----DLLETFMDPYRNIFLVMEFMDCNLFQLFKRRQGRLFTKETA-------FNILLQI 134
Query: 817 TSGVNHLHSMKIVHRDLKPQNILIAPPKRYLSLHASKNKFRVLISDFGLCKKLEIDESSF 876
SG+ H+H +HRD+KP+NIL+ + +S +++ + + DFGL + S
Sbjct: 135 ISGIEHIHKHGFMHRDIKPENILV----KRISPKPISSRYSIKLGDFGLAR------PSV 184
Query: 877 RTNNFNNPTGTSGWRAPEIISGEVSLSES 905
++ T +RAPE++ S + S
Sbjct: 185 SSDPLTEYVSTRWYRAPELLLRSGSYNHS 213
>Hs9994197 [T] KOG0607 MAP kinase-interacting kinase and related
serine/threonine protein kinases
Length = 414
Score = 58.9 bits (141), Expect = 4e-08
Identities = 68/287 (23%), Positives = 119/287 (40%), Gaps = 58/287 (20%)
Query: 749 KEIQLLSESDDHPNVIRYY-FSESTEKFMYIAVELCSASLEDVIEGSKGLAKNVAVQKNI 807
+E+++L + H NV+ F E ++F + ++ S+ I + +
Sbjct: 128 REVEMLYQCQGHRNVLELIEFFEEEDRFYLVFEKMRGGSILSHIHKRRHF-------NEL 180
Query: 808 DPINVLFQITSGVNHLHSMKIVHRDLKPQNILIAPPKRYLSLHASKNKFRVLISDFGLCK 867
+ V+ + S ++ LH+ I HRDLKP+NIL P + + ++ D G
Sbjct: 181 EASVVVQDVASALDFLHNKGIAHRDLKPENILCEHPNQV-------SPVKICDFDLGSGI 233
Query: 868 KLEIDESSFRTNNFNNPTGTSGWRAPEIISGEVSLSESFAXXXXXXXXXXXXXXLDVNHM 927
KL D S T P G++ + APE++ E+F+
Sbjct: 234 KLNGDCSPISTPELLTPCGSAEYMAPELV-------EAFSEEAS---------------- 270
Query: 928 DLVTKKRLTRAVDIFSLGCIFYYVLSKGEHPFGDRILREANILKGD---YRLDGIKKSIQ 984
+ KR D++SLG I Y +LS G PF R + +G+ + + +SIQ
Sbjct: 271 --IYDKR----CDLWSLGVILYILLS-GYPPFVGRCGSDCGWDRGEACPACQNMLFESIQ 323
Query: 985 E----------RSVCIEAADLIKSMLEQNPLLRPASDEILKHPLFWG 1021
E + A DLI +L ++ R ++ ++L+HP G
Sbjct: 324 EGKYEFPDKDWAHISCAAKDLISKLLVRDAKQRLSAAQVLQHPWVQG 370
>Hs7706401 [T] KOG0577 Serine/threonine protein kinase
Length = 1235
Score = 58.9 bits (141), Expect = 4e-08
Identities = 55/192 (28%), Positives = 84/192 (43%), Gaps = 37/192 (19%)
Query: 713 RVLGYGSSGTVVFQGKFQNRPV-AVKRLLID-------FYDIASKEIQLLSESDDHPNVI 764
R +G+GS G V F +N V A+K++ + DI KE++ L + HPN I
Sbjct: 32 REIGHGSFGAVYFARDVRNSEVVAIKKMSYSGKQSNEKWQDII-KEVRFLQKLR-HPNTI 89
Query: 765 RYYFSESTEKFMYIAVELCSASLEDVIEGSKGLAKNVAVQKNIDPINVLFQITSGVNHLH 824
+Y E ++ +E C S D++E K + V + V G+ +LH
Sbjct: 90 QYRGCYLREHTAWLVMEYCLGSASDLLEVHKKPLQEVEIAA------VTHGALQGLAYLH 143
Query: 825 SMKIVHRDLKPQNILIAPPKRYLSLHASKNKFRVLISDFGLCKKLEIDESSFRTNNFNNP 884
S ++HRD+K NIL++ P V + DFG S+ N+
Sbjct: 144 SHNMIHRDVKAGNILLSEPG------------LVKLGDFG---------SASIMAPANSF 182
Query: 885 TGTSGWRAPEII 896
GT W APE+I
Sbjct: 183 VGTPYWMAPEVI 194
>Hs4759208 [T] KOG0577 Serine/threonine protein kinase
Length = 1049
Score = 58.9 bits (141), Expect = 4e-08
Identities = 55/192 (28%), Positives = 84/192 (43%), Gaps = 37/192 (19%)
Query: 713 RVLGYGSSGTVVFQGKFQNRPV-AVKRLLID-------FYDIASKEIQLLSESDDHPNVI 764
R +G+GS G V F +N V A+K++ + DI KE++ L + HPN I
Sbjct: 32 REIGHGSFGAVYFARDVRNSEVVAIKKMSYSGKQSNEKWQDII-KEVRFLQKLR-HPNTI 89
Query: 765 RYYFSESTEKFMYIAVELCSASLEDVIEGSKGLAKNVAVQKNIDPINVLFQITSGVNHLH 824
+Y E ++ +E C S D++E K + V + V G+ +LH
Sbjct: 90 QYRGCYLREHTAWLVMEYCLGSASDLLEVHKKPLQEVEIAA------VTHGALQGLAYLH 143
Query: 825 SMKIVHRDLKPQNILIAPPKRYLSLHASKNKFRVLISDFGLCKKLEIDESSFRTNNFNNP 884
S ++HRD+K NIL++ P V + DFG S+ N+
Sbjct: 144 SHNMIHRDVKAGNILLSEPG------------LVKLGDFG---------SASIMAPANSF 182
Query: 885 TGTSGWRAPEII 896
GT W APE+I
Sbjct: 183 VGTPYWMAPEVI 194
>Hs19424132 [D] KOG0591 NIMA (never in mitosis)-related G2-specific
serine/threonine protein kinase
Length = 302
Score = 58.9 bits (141), Expect = 4e-08
Identities = 40/118 (33%), Positives = 63/118 (52%), Gaps = 17/118 (14%)
Query: 733 PVAVKRLLI-DFYDIAS-----KEIQLLSESDDHPNVIRYYFSESTEKFMYIAVELCSAS 786
PVA+K++ I D D + KEI LL + + HPNVI+YY S + + I +EL A
Sbjct: 59 PVALKKVQIFDLMDAKARADCIKEIDLLKQLN-HPNVIKYYASFIEDNELNIVLELADAG 117
Query: 787 LEDVIEGSKGLAKNVAVQKNIDPINVLF----QITSGVNHLHSMKIVHRDLKPQNILI 840
+ K+ QK + P ++ Q+ S + H+HS +++HRD+KP N+ I
Sbjct: 118 ------DLSRMIKHFKKQKRLIPERTVWKYFVQLCSALEHMHSRRVMHRDIKPANVFI 169
>Hs16936530 [R] KOG0594 Protein kinase PCTAIRE and related kinases
Length = 264
Score = 58.9 bits (141), Expect = 4e-08
Identities = 45/159 (28%), Positives = 76/159 (47%), Gaps = 24/159 (15%)
Query: 715 LGYGSSGTVV-FQGKFQNRPVAVKRLLIDFY-----DIASKEIQLLSESDDHPNVIRYYF 768
+G G+ G V + K VA+K++ +D A +EI LL E + HPN+++
Sbjct: 10 IGEGTYGVVYKARNKLTGEVVALKKIRLDTETEGVPSTAIREISLLKELN-HPNIVKLLD 68
Query: 769 SESTEKFMYIAVELCSASLEDVIEGSKGLAKNVAVQKNIDPINVLFQITSGVNHLHSMKI 828
TE +Y+ E L+ ++ S + + K+ LFQ+ G+ HS ++
Sbjct: 69 VIHTENKLYLVFEFLHQDLKKFMDASALTGIPLPLIKSY-----LFQLLQGLAFCHSHRV 123
Query: 829 VHRDLKPQNILIAPPKRYLSLHASKNKFRVLISDFGLCK 867
+HRDLKPQN+LI + + ++DFGL +
Sbjct: 124 LHRDLKPQNLLI------------NTEGAIKLADFGLAR 150
>CE29612 [R] KOG0594 Protein kinase PCTAIRE and related kinases
Length = 426
Score = 58.9 bits (141), Expect = 4e-08
Identities = 58/202 (28%), Positives = 92/202 (44%), Gaps = 41/202 (20%)
Query: 715 LGYGSSGTVV-FQGKFQNRPVAVKRLLIDFYD----IASKEIQLLSESDDHPNVIR---- 765
LG GS TV + K VA+K + + F + A +E LL H N++
Sbjct: 114 LGEGSYATVYKCESKLDGSIVALKEIKLQFQEGLPFTAIREASLLRNLR-HANIVSLHDI 172
Query: 766 -YYFSESTEKFMYIAVELCSASLEDVIEGSKGLAKNVAVQKNIDPINVLFQITSGVNHLH 824
Y + T F Y+ ++L SK L +NV +ID +LFQ+ G++ H
Sbjct: 173 FYQHHQLTFVFEYMKMDL-----------SKYLEQNVYGLDSIDIKLLLFQLLRGLDFCH 221
Query: 825 SMKIVHRDLKPQNILIAPPKRYLSLHASKNKFRVL-ISDFGLCKKLEIDESSFRTNNFNN 883
KI+HRDLKPQN+L+ ++ VL ++DFGL + S + +++
Sbjct: 222 RKKILHRDLKPQNLLL-------------DEDGVLKLADFGLAR-----AKSVPSRTYSH 263
Query: 884 PTGTSGWRAPEIISGEVSLSES 905
T +R P+++ G S S
Sbjct: 264 EVVTLWYRPPDVLMGSTDYSTS 285
>At5g12090 [T] KOG0198 MEKK and related serine/threonine protein kinases
Length = 369
Score = 58.9 bits (141), Expect = 4e-08
Identities = 80/320 (25%), Positives = 132/320 (41%), Gaps = 62/320 (19%)
Query: 741 IDFYDIASKEIQLLSESDDHPNVIRYYFSESTEKFMYIAVELCSASLEDVIEGS-KGLAK 799
++ YD +EIQ+LSE +PN++ Y + E F ++ LE EGS +
Sbjct: 66 LEEYDALKREIQILSELKGYPNIVICYGDDLEEDFNEHGHKVYKLLLEYANEGSLSSFME 125
Query: 800 NVAVQKNIDPI--NVLFQITSGVNHLHSMKIVHRDLKPQNILIAPPKRYLSLHASKNKFR 857
N +K DP+ + I G+ +HS VH DLK N+LI K S
Sbjct: 126 NYPDRKLPDPMIRDFTRMILEGLVSMHSHGYVHCDLKSDNLLIFSRKDSASC-------E 178
Query: 858 VLISDFGLCKKL-EIDESSFRTNNFNNPTGTSGWRAPEIISGEVSLSESFAXXXXXXXXX 916
+ I DFG C+++ E+ + W++ V ESF
Sbjct: 179 LKIFDFGNCRQVGEVPDH---------------WKSD---YPYVGTPESF---------- 210
Query: 917 XXXXXLDVNHMDLVTKKRLTRAVDIFSLGCIFYYVLSKGEHPFGDRILREANILKGDYRL 976
D V KK L D++SLGC+ + + GE P+ R ++ ++
Sbjct: 211 ----------FDGVAKKTL----DLWSLGCLVLKIYT-GEQPWE----RVTSVDFVNFLS 251
Query: 977 DGIKKSIQERSVCIEAADLIKSMLEQNPLLRPASDEILKHPLF---WGVSKKLEFLLKVS 1033
DG +I E C +A + I++ + R + E+L HP + KL+ +K +
Sbjct: 252 DGEAPNIPEYVPC-DAREFIETCFAREHEKRGTASELLLHPFLCQKQPLLVKLKLRIKQA 310
Query: 1034 DRFEVERRDPPSPLLLKLEE 1053
+ + R+ P L + L +
Sbjct: 311 SKITMGIREKPLTLKMFLSK 330
>7300650 [R] KOG0594 Protein kinase PCTAIRE and related kinases
Length = 314
Score = 58.9 bits (141), Expect = 4e-08
Identities = 77/335 (22%), Positives = 139/335 (40%), Gaps = 85/335 (25%)
Query: 715 LGYGSSGTVVFQGKFQN--RPVAVKRLLID-----FYDIASKEIQLLSESDDHPNVIRYY 767
+G G+ G +V++ + + + VA+K++ ++ A +EI LL HPNV++ +
Sbjct: 14 IGEGTYG-IVYKARSNSTGQDVALKKIRLEGETEGVPSTAIREISLLKNLK-HPNVVQLF 71
Query: 768 FSESTEKFMYIAVELCSASLEDVIEGSKGLAKNVAVQKNIDPINVLFQITSGVNHLHSMK 827
+ +Y+ E + L+ +++ K + ++ + + QI V H+ +
Sbjct: 72 DVVISGNNLYMIFEYLNMDLKKLMDKKKDVFTPQLIK------SYMHQILDAVGFCHTNR 125
Query: 828 IVHRDLKPQNILIAPPKRYLSLHASKNKFRVLISDFGLCKKLEIDESSFRTNNFNNPTGT 887
I+HRDLKPQN+L+ ++ ++DFGL + + + + + T
Sbjct: 126 ILHRDLKPQNLLV------------DTAGKIKLADFGLARAFNVPMRA-----YTHEVVT 168
Query: 888 SGWRAPEIISGEVSLSESFAXXXXXXXXXXXXXXLDVNHMDLVTKKRLTRAVDIFSLGCI 947
+RAPEI+ G K + VDI+SLGCI
Sbjct: 169 LWYRAPEILLG---------------------------------TKFYSTGVDIWSLGCI 195
Query: 948 FYYVLSKGEHPFGD-------RILR-----EANILKGDYRLDGIK--------KSIQERS 987
F ++ + GD RI R + G +L K ++ +
Sbjct: 196 FSEMIMRRSLFPGDSEIDQLYRIFRTLSTPDETNWPGVTQLPDFKTKFPRWEGTNMPQPI 255
Query: 988 VCIEAADLIKSMLEQNPLLRPASDEILKHPLFWGV 1022
EA +LI SML +P LR ++ + L+H F V
Sbjct: 256 TEHEAHELIMSMLCYDPNLRISAKDALQHAYFRNV 290
>7300435 [T] KOG4645 MAPKKK (MAP kinase kinase kinase) SSK2 and related
serine/threonine protein kinases
Length = 1612
Score = 58.9 bits (141), Expect = 4e-08
Identities = 66/270 (24%), Positives = 112/270 (41%), Gaps = 58/270 (21%)
Query: 748 SKEIQLLSESDDHPNVIRYYFSESTEKFMYIAVELCS-ASLEDVIEGSKGLAKNVAVQKN 806
++E+++L E H N++RYY E + + I +ELCS +LE ++E + L + + +
Sbjct: 1368 AEELKIL-EGIKHKNLVRYYGIEVHREELLIFMELCSEGTLESLVELTGNLPEALTRRFT 1426
Query: 807 IDPINVLFQITSGVNHLHSMKIVHRDLKPQNILIAPPKRYLSLHASKNKFRVLISDFGLC 866
Q+ SGV+ LH IVHRD+K NI + L L DFG
Sbjct: 1427 A-------QLLSGVSELHKHGIVHRDIKTANIFLVDGSNSLKL-----------GDFGSA 1468
Query: 867 KKLEIDESSFRTNNFNNPTGTSGWRAPEIISGEVSLSESFAXXXXXXXXXXXXXXLDVNH 926
K++ + GT + APE+ + S
Sbjct: 1469 VKIQAHTTV--PGELQGYVGTQAYMAPEVFTKTNSDGHG--------------------- 1505
Query: 927 MDLVTKKRLTRAVDIFSLGCIFYYVLSKGEHPFGDRILREANILKGDYRLDGIKKSIQER 986
RA DI+S+GC+ + S G+ P+ ++N + +++ +K
Sbjct: 1506 ----------RAADIWSVGCVVVEMAS-GKRPWAQ---FDSN-FQIMFKVGMGEKPQAPE 1550
Query: 987 SVCIEAADLIKSMLEQNPLLRPASDEILKH 1016
S+ E D I L+ +P R + E+L+H
Sbjct: 1551 SLSQEGHDFIDHCLQHDPKRRLTAVELLEH 1580
>7294866 [K] KOG0666 Cyclin C-dependent kinase CDK8
Length = 531
Score = 58.9 bits (141), Expect = 4e-08
Identities = 56/214 (26%), Positives = 97/214 (45%), Gaps = 54/214 (25%)
Query: 747 ASKEIQLLSESDDHPNVI---RYYFSESTEKFMYIAVELCSASLEDVIE---GSKGLAKN 800
A +EI LL E H NVI R + S + K +++ ++ L +I+ +K K
Sbjct: 140 ACREIALLRELK-HQNVITLIRVFLSHNDRK-VFLLIDYAEHDLWHIIKFHRAAKATKKQ 197
Query: 801 VAVQKNIDPINVLFQITSGVNHLHSMKIVHRDLKPQNILIAPPKRYLSLHASKNKFRVLI 860
V V + + ++L+QI G+++LHS ++HRDLKP NIL+ + + RV I
Sbjct: 198 VVVPRGMVK-SLLYQILDGIHYLHSNWVLHRDLKPANILV--------MGDGNERGRVKI 248
Query: 861 SDFGLCKKLEIDESSFRTNNFNNPTGTSGW-RAPEIISGEVSLSESFAXXXXXXXXXXXX 919
+D G + + + + +P + W RAPE++ G
Sbjct: 249 ADMGFAR---LFNAPLKPLADLDPVVVTFWYRAPELLLG--------------------- 284
Query: 920 XXLDVNHMDLVTKKRLTRAVDIFSLGCIFYYVLS 953
+ T+A+DI+++GCIF +L+
Sbjct: 285 ------------ARHYTKAIDIWAIGCIFAELLT 306
>Hs7705841 [T] KOG1187 Serine/threonine protein kinase
Length = 460
Score = 58.5 bits (140), Expect = 6e-08
Identities = 53/205 (25%), Positives = 92/205 (44%), Gaps = 35/205 (17%)
Query: 708 LSISSRVLGYGSSGTVVFQGKFQNRPVAVKRLLIDFYDIASKEIQLLSESD-------DH 760
+S+ +G G G VV++G N VAVK+L DI ++E++ + + H
Sbjct: 185 ISVGGNKMGEGGFG-VVYKGYVNNTTVAVKKLAA-MVDITTEELKQQFDQEIKVMAKCQH 242
Query: 761 PNVIRYY-FSESTEKFMYIAVELCSASLED---VIEGSKGLAKNVAVQKNIDPINVLFQI 816
N++ FS + + V + + SL D ++G+ L+ ++ + +
Sbjct: 243 ENLVELLGFSSDGDDLCLVYVYMPNGSLLDRLSCLDGTPPLSWHMRCK-------IAQGA 295
Query: 817 TSGVNHLHSMKIVHRDLKPQNILIAPPKRYLSLHASKNKFRVLISDFGLCKKLEIDESSF 876
+G+N LH +HRD+K NIL+ F ISDFGL + E +
Sbjct: 296 ANGINFLHENHHIHRDIKSANILL------------DEAFTAKISDFGLARASEKFAQTV 343
Query: 877 RTNNFNNPTGTSGWRAPEIISGEVS 901
T+ GT+ + APE + GE++
Sbjct: 344 MTSRI---VGTTAYMAPEALRGEIT 365
>Hs16160923 [R] KOG0594 Protein kinase PCTAIRE and related kinases
Length = 472
Score = 58.5 bits (140), Expect = 6e-08
Identities = 51/197 (25%), Positives = 89/197 (44%), Gaps = 35/197 (17%)
Query: 715 LGYGSSGTVVFQG--KFQNRPVAVKRLLIDFYD----IASKEIQLLSESDDHPNVIRYYF 768
LG G+ TV F+G K VA+K + ++ + A +E+ LL H N++ +
Sbjct: 148 LGEGTYATV-FKGRSKLTENLVALKEIRLEHEEGAPCTAIREVSLLKNLK-HANIVTLHD 205
Query: 769 SESTEKFMYIAVELCSASLEDVIEGSKGLAK--NVAVQKNIDPINVLFQITSGVNHLHSM 826
T++ + + E + L+ ++ L NV + +FQ+ G+ + H
Sbjct: 206 LIHTDRSLTLVFEYLDSDLKQYLDHCGNLMSMHNVKI--------FMFQLLRGLAYCHHR 257
Query: 827 KIVHRDLKPQNILIAPPKRYLSLHASKNKFRVLISDFGLCKKLEIDESSFRTNNFNNPTG 886
KI+HRDLKPQN+LI + + ++DFGL + S T ++N
Sbjct: 258 KILHRDLKPQNLLI------------NERGELKLADFGLAR-----AKSVPTKTYSNEVV 300
Query: 887 TSGWRAPEIISGEVSLS 903
T +R P+++ G S
Sbjct: 301 TLWYRPPDVLLGSTEYS 317
>Hs14768528 [T] KOG1187 Serine/threonine protein kinase
Length = 460
Score = 58.5 bits (140), Expect = 6e-08
Identities = 53/205 (25%), Positives = 92/205 (44%), Gaps = 35/205 (17%)
Query: 708 LSISSRVLGYGSSGTVVFQGKFQNRPVAVKRLLIDFYDIASKEIQLLSESD-------DH 760
+S+ +G G G VV++G N VAVK+L DI ++E++ + + H
Sbjct: 185 ISVGGNKMGEGGFG-VVYKGYVNNTTVAVKKLAA-MVDITTEELKQQFDQEIKVMAKCQH 242
Query: 761 PNVIRYY-FSESTEKFMYIAVELCSASLED---VIEGSKGLAKNVAVQKNIDPINVLFQI 816
N++ FS + + V + + SL D ++G+ L+ ++ + +
Sbjct: 243 ENLVELLGFSSDGDDLCLVYVYMPNGSLLDRLSCLDGTPPLSWHMRCK-------IAQGA 295
Query: 817 TSGVNHLHSMKIVHRDLKPQNILIAPPKRYLSLHASKNKFRVLISDFGLCKKLEIDESSF 876
+G+N LH +HRD+K NIL+ F ISDFGL + E +
Sbjct: 296 ANGINFLHENHHIHRDIKSANILL------------DEAFTAKISDFGLARASEKFAQTV 343
Query: 877 RTNNFNNPTGTSGWRAPEIISGEVS 901
T+ GT+ + APE + GE++
Sbjct: 344 MTSRI---VGTTAYMAPEALRGEIT 365
>CE26212 [T] KOG0582 Ste20-like serine/threonine protein kinase
Length = 545
Score = 58.5 bits (140), Expect = 6e-08
Identities = 51/193 (26%), Positives = 90/193 (46%), Gaps = 24/193 (12%)
Query: 715 LGYGSSGTVVFQGKF-QNRPVAVKRLLID----FYDIASKEIQLLSESDDHPNVIRYYFS 769
+G G++ TV +N VA+K + ++ D S EIQ +S+ + HPNV+ YY S
Sbjct: 63 IGVGATATVFTAYCLPRNEKVAIKCINLEKCQTSVDELSHEIQAMSQCN-HPNVVSYYTS 121
Query: 770 ESTEKFMYIAVEL--CSASLEDVIEGSKGLAKNVAVQKNIDPIN---VLFQITSGVNHLH 824
++ +++ + L C + L+ + K + K A +D ++ VL ++ G+ + H
Sbjct: 122 FIAQEELWVVMRLLNCGSMLDILKRKVKAIGKEQAQFGVLDEVSIATVLREVLKGLEYFH 181
Query: 825 SMKIVHRDLKPQNILIAPPKRYLSLHASKNKFRVLISDFGLCKKLEIDESSFRTNNFNNP 884
+HRD+K NIL+A + + I+DFG+ L +
Sbjct: 182 LNGQIHRDIKAGNILLA------------DDGTIQIADFGVSGWLASSGGDLSRQKVRHT 229
Query: 885 -TGTSGWRAPEII 896
GT W APE++
Sbjct: 230 FVGTPCWMAPEVM 242
>At5g58950 [T] KOG0192 Tyrosine kinase specific for activated (GTP-bound)
p21cdc42Hs
Length = 561
Score = 58.5 bits (140), Expect = 6e-08
Identities = 49/185 (26%), Positives = 88/185 (47%), Gaps = 36/185 (19%)
Query: 724 VFQGKFQNRPVAVKRLLIDFYDIA-----------SKEIQLLSESDDHPNVIRYYFS-ES 771
++ GK++++ VAVK + + D +KE+ LLS HPNVI++ + +
Sbjct: 257 LYHGKYEDKAVAVKLITVPDDDDNGCLGARLEKQFTKEVTLLSRLT-HPNVIKFVGAYKD 315
Query: 772 TEKFMYIAVELCSASLEDVIEGSKGLAKNVAVQKNIDPINVLFQITSGVNHLHSMKIVHR 831
+ + L SL + + +++ ++K I+ I G+ ++HS +I+HR
Sbjct: 316 PPVYCVLTQYLPEGSLRSFLHKPEN--RSLPLKKLIE---FAIDIARGMEYIHSRRIIHR 370
Query: 832 DLKPQNILIAPPKRYLSLHASKNKFRVLISDFGLCKKLEIDESSFRTNNFNNPTGTSGWR 891
DLKP+N+LI +F + I+DFG+ + E + + GT W
Sbjct: 371 DLKPENVLI------------DEEFHLKIADFGIACEEEY------CDMLADDPGTYRWM 412
Query: 892 APEII 896
APE+I
Sbjct: 413 APEMI 417
>At3g54180 [R] KOG0594 Protein kinase PCTAIRE and related kinases
Length = 309
Score = 58.5 bits (140), Expect = 6e-08
Identities = 64/283 (22%), Positives = 109/283 (37%), Gaps = 83/283 (29%)
Query: 769 SESTEKFMYIAVELCSASLEDVIEGSKGLAKNVAVQKNIDPI---NVLFQITSGVNHLHS 825
S+ST+ +Y+ E L+ I+ + K ++P ++FQ+ GV H HS
Sbjct: 80 SQSTKSNLYLVFEYLDTDLKKFIDSYRKGPN----PKPLEPFLIQKLMFQLCKGVAHCHS 135
Query: 826 MKIVHRDLKPQNILIAPPKRYLSLHASKNKFRVLISDFGLCKKLEIDESSFRTNNFNNPT 885
++HRDLKPQN+L+ K L I+D GL + + S + +
Sbjct: 136 HGVLHRDLKPQNLLLVKDKELLK-----------IADLGLGRAFTVPLKS-----YTHEI 179
Query: 886 GTSGWRAPEIISGEVSLSESFAXXXXXXXXXXXXXXLDVNHMDLVTKKRLTRAVDIFSLG 945
T +RAPE++ G S VD++S+G
Sbjct: 180 VTLWYRAPEVLLGSTHYS---------------------------------TGVDMWSVG 206
Query: 946 CIFYYVLSK-----GEHPF-------------------GDRILREANILKGDYRLDGIKK 981
CIF ++ + G+ F G LR+ ++ + +
Sbjct: 207 CIFAEMVRRQALFPGDSEFQQLLHIFRLLGTPTEQQWPGVSTLRDWHVYP---KWEPQDL 263
Query: 982 SIQERSVCIEAADLIKSMLEQNPLLRPASDEILKHPLFWGVSK 1024
++ S+ + DL+ ML+ NP R ++ L HP F + K
Sbjct: 264 TLAVPSLSPQGVDLLTKMLKYNPAERISAKTALDHPYFDSLDK 306
>At2g43790 [T] KOG0660 Mitogen-activated protein kinase
Length = 395
Score = 58.5 bits (140), Expect = 6e-08
Identities = 83/342 (24%), Positives = 137/342 (39%), Gaps = 103/342 (30%)
Query: 715 LGYGSSGTVVFQGKFQ-NRPVAVKRLLIDFYDIAS-----KEIQLLSESDDHPNVI---- 764
+G G+ G V + N VA+K++ F + +EI+LL D H N++
Sbjct: 69 IGKGAYGIVCSAMNSETNESVAIKKIANAFDNKIDAKRTLREIKLLRHMD-HENIVAIRD 127
Query: 765 ------RYYFSESTEKFMYIAVELCSASLEDVIEGSKGLAKNVAVQKNIDPINVLFQITS 818
R F++ +YIA EL L +I ++ L++ L+QI
Sbjct: 128 IIPPPLRNAFND-----VYIAYELMDTDLHQIIRSNQALSEEHCQY-------FLYQILR 175
Query: 819 GVNHLHSMKIVHRDLKPQNILIAPPKRYLSLHASKNKFRVLISDFGLCKKLEIDESSFRT 878
G+ ++HS ++HRDLKP N+L L+A+ + + I DFGL + ES F T
Sbjct: 176 GLKYIHSANVLHRDLKPSNLL---------LNANCD---LKICDFGLAR--VTSESDFMT 221
Query: 879 NNFNNPTGTSGWRAPEIISGEVSLSESFAXXXXXXXXXXXXXXLDVNHMDLVTKKRLTRA 938
T +RAPE+ L+ T A
Sbjct: 222 EY----VVTRWYRAPEL---------------------------------LLNSSDYTAA 244
Query: 939 VDIFSLGCIFYYVLSK------GEHPFGDRILREANILKGDYRLDGI------------- 979
+D++S+GCIF ++ + +H R+L E + L+ +
Sbjct: 245 IDVWSVGCIFMELMDRKPLFPGRDHVHQLRLLMELIGTPSEEELEFLNENAKRYIRQLPP 304
Query: 980 --KKSIQERSVCIE--AADLIKSMLEQNPLLRPASDEILKHP 1017
++SI ++ + A DLI+ ML +P R + L HP
Sbjct: 305 YPRQSITDKFPTVHPLAIDLIEKMLTFDPRRRITVLDALAHP 346
>At2g42960 [T] KOG1187 Serine/threonine protein kinase
Length = 494
Score = 58.5 bits (140), Expect = 6e-08
Identities = 60/187 (32%), Positives = 88/187 (46%), Gaps = 25/187 (13%)
Query: 714 VLGYGSSGTVVFQGKFQN-RPVAVKRLLIDFYDIASKEIQLLSESDDH---PNVIRY--Y 767
VLG G G VV++GK N VAVK+LL + A KE ++ E+ H N++R Y
Sbjct: 188 VLGEGGYG-VVYRGKLVNGTEVAVKKLLNNLGQ-AEKEFRVEVEAIGHVRHKNLVRLLGY 245
Query: 768 FSESTEKFMYIAVELCSASLEDVIEGSKGLAKNVAVQKNIDPINVLFQITSGVNHLHSMK 827
E + M + + S +LE + G+ N+ + + I Q + ++ K
Sbjct: 246 CIEGVHR-MLVYEYVNSGNLEQWLHGAMRQHGNLTWEARMKIITGTAQALAYLHEAIEPK 304
Query: 828 IVHRDLKPQNILIAPPKRYLSLHASKNKFRVLISDFGLCKKLEIDESSFRTNNFNNPTGT 887
+VHRD+K NILI ++F +SDFGL K L+ ES T GT
Sbjct: 305 VVHRDIKASNILI------------DDEFNAKLSDFGLAKLLDSGESHITT----RVMGT 348
Query: 888 SGWRAPE 894
G+ APE
Sbjct: 349 FGYVAPE 355
>YPL031c [R] KOG0594 Protein kinase PCTAIRE and related kinases
Length = 305
Score = 58.2 bits (139), Expect = 8e-08
Identities = 56/203 (27%), Positives = 91/203 (44%), Gaps = 38/203 (18%)
Query: 715 LGYGSSGTVVFQG--KFQNRPVAVKRLLIDFYD----IASKEIQLLSESDDHPNVIRYYF 768
LG G+ TV ++G K VA+K + +D + A +EI L+ E H N++R Y
Sbjct: 13 LGNGTYATV-YKGLNKTTGVYVALKEVKLDSEEGTPSTAIREISLMKELK-HENIVRLYD 70
Query: 769 SESTEKFMYIAVELCSASLEDVIEGS------KGLAKNVAVQKNIDPINVLFQITSGVNH 822
TE + + E L+ ++ +GL N+ +Q+ G+
Sbjct: 71 VIHTENKLTLVFEFMDNDLKKYMDSRTVGNTPRGLELNLVKYFQ-------WQLLQGLAF 123
Query: 823 LHSMKIVHRDLKPQNILIAPPKRYLSLHASKNKFRVLISDFGLCKKLEIDESSFRTNNFN 882
H KI+HRDLKPQN+LI + ++ + DFGL + I N F+
Sbjct: 124 CHENKILHRDLKPQNLLI------------NKRGQLKLGDFGLARAFGIP-----VNTFS 166
Query: 883 NPTGTSGWRAPEIISGEVSLSES 905
+ T +RAP+++ G + S S
Sbjct: 167 SEVVTLWYRAPDVLMGSRTYSTS 189
>YKL139w [D] KOG0600 Cdc2-related protein kinase
Length = 528
Score = 58.2 bits (139), Expect = 8e-08
Identities = 62/194 (31%), Positives = 94/194 (47%), Gaps = 38/194 (19%)
Query: 715 LGYGSSGTVVFQGKFQN--RPVAVKRLLID-----FYDIASKEIQLLSESDDHPNV--IR 765
+G G+ G V ++ K N + VA+K+L + F + +EI+LL +S DHPNV I+
Sbjct: 189 VGEGTYGKV-YKAKNTNTEKLVALKKLRLQGEREGFPITSIREIKLL-QSFDHPNVSTIK 246
Query: 766 YYFSESTEKFMYIAVELCSASLEDVIEGSKGLAKNVAVQKNIDPINVLF-QITSGVNHLH 824
ES +K +Y+ E L GL N VQ + LF Q+ G+ +LH
Sbjct: 247 EIMVES-QKTVYMIFEYADNDLS-------GLLLNKEVQISHSQCKHLFKQLLLGMEYLH 298
Query: 825 SMKIVHRDLKPQNILIAPPKRYLSLHASKNKFRVLISDFGLCKKLEIDESSFRTNNFNNP 884
KI+HRD+K NILI N+ + I+DFGL +K+ ++ N
Sbjct: 299 DNKILHRDVKGSNILI------------DNQGNLKITDFGLARKMN------SRADYTNR 340
Query: 885 TGTSGWRAPEIISG 898
T +R PE++ G
Sbjct: 341 VITLWYRPPELLLG 354
>YER129w [T] KOG0585 Ca2+/calmodulin-dependent protein kinase kinase beta and
related serine/threonine protein kinases
Length = 1142
Score = 58.2 bits (139), Expect = 8e-08
Identities = 82/355 (23%), Positives = 138/355 (38%), Gaps = 61/355 (17%)
Query: 736 VKRLLIDFYDIASKEIQLLSESDDHPNVIRYY--FSESTEKFMYIAVELCSASL-----E 788
+K I D +EI ++ + H +V++ + + +Y+ +E CS
Sbjct: 178 IKSSKISENDKIKREIAIMKKCH-HKHVVQLIEVLDDLKSRKIYLVLEYCSRGEVKWCPP 236
Query: 789 DVIEGSKGLAKNVAVQKNIDPINVLFQITSGVNHLHSMKIVHRDLKPQNILIAPPKRYLS 848
D +E AK ++ + +L + G+ +LH I+HRD+KP N+LI+
Sbjct: 237 DCMESD---AKGPSLLSFQETREILRGVVLGLEYLHYQGIIHRDIKPANLLIS------- 286
Query: 849 LHASKNKFRVLISDFGLCKKLEIDESSFRTNNFN-----NPTGTSGWRAPEIISGEVSLS 903
V ISDFG+ SS + + + GT + APE+ GE + +
Sbjct: 287 -----GDGTVKISDFGVSLAASSTNSSDSSESLDELELAKTVGTPAFFAPEMCLGEDAFT 341
Query: 904 ESFAXXXXXXXXXXXXXXLDVNHMDLVTKKRLTRAVDIFSLGCIFYYVLSKGEHPFGDRI 963
++ +L ++ +DI+++G Y +L F D
Sbjct: 342 R-----------------YNLTKENLFRGSCISFMIDIWAVGVTLYCLLFGMLPFFSDFE 384
Query: 964 LREANILKGDYRLDGIKKSIQERSV----CIE----AADLIKSMLEQNPLLRPASDEILK 1015
L+ + D K IQ V C E A DL+ +LE+NP R I K
Sbjct: 385 LKLFEKIVNDPLKFPTFKEIQSNKVSKVSCEEEYEMAKDLLLKLLEKNPQKRMTIPAIKK 444
Query: 1016 HP-LFWGV-------SKKLEFLLKVSDRFEVERRDPPSPLLLKLEEVSAKVITTG 1062
HP + W K L +L+ RF+ + D P+ + E+ V G
Sbjct: 445 HPFVSWDFDHVPENDEKLLSSVLEQKLRFQCNQTDQFEPISISKHELKNAVSGVG 499
>HsM4758524 [T] KOG0587 Traf2- and Nck-interacting kinase and related germinal
center kinase (GCK) family protein kinases
Length = 1165
Score = 58.2 bits (139), Expect = 8e-08
Identities = 53/195 (27%), Positives = 91/195 (46%), Gaps = 34/195 (17%)
Query: 714 VLGYGSSGTVVFQGKF----QNRPVAVKRLLIDFYDIASKEIQLLSESDDHPNVIRYYFS 769
V+G G+ G V ++G+ Q + V + D + EI +L + H N+ YY +
Sbjct: 30 VVGNGTYGQV-YKGRHVKTGQLAAIKVMDVTEDEEEEIKLEINMLKKYSHHRNIATYYGA 88
Query: 770 ------ESTEKFMYIAVELCSA-SLEDVIEGSKGLAKNVAVQKNIDPINVLFQITSGVNH 822
+ +++ +E C A S+ D+++ +KG N + I I+ +I G+ H
Sbjct: 89 FIKKSPPGHDDQLWLVMEFCGAGSITDLVKNTKG---NTLKEDWIAYISR--EILRGLAH 143
Query: 823 LHSMKIVHRDLKPQNILIAPPKRYLSLHASKNKFRVLISDFGLCKKLEIDESSFRTNNFN 882
LH ++HRD+K QN+L+ V + DFG+ ++D + R N F
Sbjct: 144 LHIHHVIHRDIKGQNVLLT------------ENAEVKLVDFGV--SAQLDRTVGRRNTF- 188
Query: 883 NPTGTSGWRAPEIIS 897
GT W APE+I+
Sbjct: 189 --IGTPYWMAPEVIA 201
>Hs4507361 [T] KOG0192 Tyrosine kinase specific for activated (GTP-bound)
p21cdc42Hs
Length = 579
Score = 58.2 bits (139), Expect = 8e-08
Identities = 59/209 (28%), Positives = 95/209 (45%), Gaps = 40/209 (19%)
Query: 694 LDFKEFEQEGHLKHLSISSRVLGYGSSGTVVFQGKFQNRPVAVKRLLIDFYDIAS-KEIQ 752
+D+KE E E V+G G+ G VV + K++ + VA+K++ + A E++
Sbjct: 31 IDYKEIEVE----------EVVGRGAFG-VVCKAKWRAKDVAIKQIESESERKAFIVELR 79
Query: 753 LLSESDDHPNVIRYYFSESTEKFMYIAVELCSASLEDVIEGSKGLAKNVAVQKNIDPINV 812
LS + HPN+++ Y + SL +V+ G++ L A ++
Sbjct: 80 QLSRVN-HPNIVKLY-GACLNPVCLVMEYAEGGSLYNVLHGAEPLPYYTAAHA----MSW 133
Query: 813 LFQITSGVNHLHSMK---IVHRDLKPQNILIAPPKRYLSLHASKNKFRVLISDFGLCKKL 869
Q + GV +LHSM+ ++HRDLKP N+L+ L I DFG
Sbjct: 134 CLQCSQGVAYLHSMQPKALIHRDLKPPNLLLVAGGTVLK-----------ICDFGTA--- 179
Query: 870 EIDESSFRTNNFNNPTGTSGWRAPEIISG 898
D + TNN G++ W APE+ G
Sbjct: 180 -CDIQTHMTNN----KGSAAWMAPEVFEG 203
>Hs4502745 [K] KOG0666 Cyclin C-dependent kinase CDK8
Length = 464
Score = 58.2 bits (139), Expect = 8e-08
Identities = 80/336 (23%), Positives = 141/336 (41%), Gaps = 98/336 (29%)
Query: 747 ASKEIQLLSESDDHPNVI--RYYFSESTEKFMYIAVELCSASLEDVIE---GSKGLAKNV 801
A +EI LL E HPNVI + F ++ +++ + L +I+ SK K V
Sbjct: 63 ACREIALLRELK-HPNVISLQKVFLSHADRKVWLLFDYAEHDLWHIIKFHRASKANKKPV 121
Query: 802 AVQKNIDPINVLFQITSGVNHLHSMKIVHRDLKPQNILIAPPKRYLSLHASKNKFRVLIS 861
+ + + ++L+QI G+++LH+ ++HRDLKP NIL+ + + RV I+
Sbjct: 122 QLPRGMVK-SLLYQILDGIHYLHANWVLHRDLKPANILV--------MGEGPERGRVKIA 172
Query: 862 DFGLCKKLEIDESSFRTNNFNNPTGTSGW-RAPEIISGEVSLSESFAXXXXXXXXXXXXX 920
D G + + S + +P + W RAPE++ G
Sbjct: 173 DMGFAR---LFNSPLKPLADLDPVVVTFWYRAPELLLG---------------------- 207
Query: 921 XLDVNHMDLVTKKRLTRAVDIFSLGCIFYYVLS------------KGEHPFG----DRI- 963
+ T+A+DI+++GCIF +L+ K +P+ DRI
Sbjct: 208 -----------ARHYTKAIDIWAIGCIFAELLTSEPIFHCRQEDIKTSNPYHHDQLDRIF 256
Query: 964 ----------------LREANILKGDYRLD-----GIKKSIQERSV--CIEAADLIKSML 1000
+ E + L D+R + + K +++ V +A L++ +L
Sbjct: 257 NVMGFPADKDWEDIKKMPEHSTLMKDFRRNTYTNCSLIKYMEKHKVKPDSKAFHLLQKLL 316
Query: 1001 EQNPLLRPASDEILKHPLFWGVSKKLEFLLKVSDRF 1036
+P+ R S++ ++ P F LE L SD F
Sbjct: 317 TMDPIKRITSEQAMQDPYF------LEDPLPTSDVF 346
Database: KOG eukaryal database 04/03
Posted date: Apr 14, 2003 1:07 PM
Number of letters in database: 30,389,216
Number of sequences in database: 60,738
Lambda K H
0.318 0.137 0.396
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 66,771,273
Number of Sequences: 60738
Number of extensions: 2913173
Number of successful extensions: 11413
Number of sequences better than 1.0e-05: 457
Number of HSP's better than 0.0 without gapping: 9
Number of HSP's successfully gapped in prelim test: 448
Number of HSP's that attempted gapping in prelim test: 10556
Number of HSP's gapped (non-prelim): 830
length of query: 1152
length of database: 30,389,216
effective HSP length: 117
effective length of query: 1035
effective length of database: 23,282,870
effective search space: 24097770450
effective search space used: 24097770450
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)