ORF STATUS Function Best COG Functional category Pathways and functional systems
r_klactIV3393 good TU KOG0998 Intracellular trafficking, secretion, and vesicular transport Synaptic vesicle protein EHS-1 and related EH domain proteins
r_klactIV3393 good TU KOG0998 Signal transduction mechanisms Synaptic vesicle protein EHS-1 and related EH domain proteins
Only best alignment is shown:
BLASTP 2.2.3 [May-13-2002]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= r_klactIV3393 1153371 1157342 1324
(1324 letters)
Database: KOG eukaryal database 04/03
60,738 sequences; 30,389,216 total letters
Searching..................................................done
Color Key for Alignment Scores: 
Score E
Sequences producing significant alignments: (bits) Value
YIR006c [TU] KOG0998 Synaptic vesicle protein EHS-1 and related ... 650 0.0
Hs4503593 [TU] KOG0998 Synaptic vesicle protein EHS-1 and relate... 82 4e-15
7291848 [TU] KOG0998 Synaptic vesicle protein EHS-1 and related ... 74 2e-12
7297819 [U] KOG1955 Ral-GTPase effector RALBP1 74 2e-12
Hs10864047 [TU] KOG0998 Synaptic vesicle protein EHS-1 and relat... 73 3e-12
YBL047c [TU] KOG0998 Synaptic vesicle protein EHS-1 and related ... 70 2e-11
Hs4504797_1 [TU] KOG1029 Endocytic adaptor protein intersectin 70 2e-11
Hs13994296 [U] KOG1955 Ral-GTPase effector RALBP1 70 2e-11
CE02903 [TU] KOG0998 Synaptic vesicle protein EHS-1 and related ... 66 4e-10
Hs11128045_1 [TU] KOG1029 Endocytic adaptor protein intersectin 66 4e-10
SPBC83.01 [TU] KOG0998 Synaptic vesicle protein EHS-1 and relate... 65 5e-10
SPBC800.10c [TU] KOG0998 Synaptic vesicle protein EHS-1 and rela... 63 4e-09
SPBC11G11.02c [TU] KOG0998 Synaptic vesicle protein EHS-1 and re... 62 5e-09
Hs4758944 [U] KOG1955 Ral-GTPase effector RALBP1 62 8e-09
At1g20760 [TU] KOG0998 Synaptic vesicle protein EHS-1 and relate... 60 2e-08
Hs21264315 [TU] KOG1954 Endocytosis/signaling protein EHD1 60 3e-08
7298751 [TU] KOG1029 Endocytic adaptor protein intersectin 60 3e-08
Hs5803009 [TU] KOG1954 Endocytosis/signaling protein EHD1 58 1e-07
Hs18578080 [TU] KOG1954 Endocytosis/signaling protein EHD1 58 1e-07
Hs7657056 [TU] KOG1954 Endocytosis/signaling protein EHD1 57 1e-07
7299673 [TU] KOG1954 Endocytosis/signaling protein EHD1 57 2e-07
HsM7657054 [TU] KOG1954 Endocytosis/signaling protein EHD1 56 3e-07
Hs21361462 [TU] KOG1954 Endocytosis/signaling protein EHD1 56 3e-07
CE23342 [TU] KOG1029 Endocytic adaptor protein intersectin 55 6e-07
CE28509 [TU] KOG1954 Endocytosis/signaling protein EHD1 55 1e-06
CE25148 [TU] KOG1954 Endocytosis/signaling protein EHD1 55 1e-06
CE25147 [TU] KOG1954 Endocytosis/signaling protein EHD1 55 1e-06
CE25146 [TU] KOG1954 Endocytosis/signaling protein EHD1 55 1e-06
At1g21630 [TU] KOG0998 Synaptic vesicle protein EHS-1 and relate... 55 1e-06
CE21667 [U] KOG1955 Ral-GTPase effector RALBP1 54 2e-06
>YIR006c [TU] KOG0998 Synaptic vesicle protein EHS-1 and related EH domain
proteins
Length = 1480
Score = 650 bits (1677), Expect = 0.0
Identities = 379/821 (46%), Positives = 499/821 (60%), Gaps = 65/821 (7%)
Query: 147 PLQPQQTGFYSQQQ---PLEPLKPTATGFINSFANTGVDNTLKIPAIRLSFITTQDQAKF 203
PL+PQQTGFY Q Q PLEPLKPTATGF+NSFAN G++N +KIPAIRLSFIT QDQAKF
Sbjct: 215 PLKPQQTGFYLQPQNQAPLEPLKPTATGFVNSFANNGLNNDIKIPAIRLSFITAQDQAKF 274
Query: 204 EKLFRSVVTPGSNTITGDQCRNILVKSGLQPHQLAKIWTLSDTNKAGVLLFPEFALAMYL 263
E LFRS+VT GSNT++G CR IL++SGL P QLA+IWTL DT+KAG LLFPEFALAM+L
Sbjct: 275 ETLFRSIVTNGSNTVSGANCRKILMRSGLPPSQLARIWTLCDTSKAGELLFPEFALAMHL 334
Query: 264 VNSVLQGDSIPYELDSRTKAEVSSFVDAINFSVSN-DSEVEQKPKTPFDD-LTAGISMMQ 321
+N VLQGD+IPYELDS+TK EVSSF+DAIN S++N DS PKTPFD+ +TAG+ +Q
Sbjct: 335 INDVLQGDTIPYELDSKTKNEVSSFIDAINLSIANQDSSANDAPKTPFDEFITAGVQNLQ 394
Query: 322 PQPTGYMPXXXX-----XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXGGYGAAPQTSFG 376
PQPTGYMP G G PQ + G
Sbjct: 395 PQPTGYMPQTSFGIPLQSQITGGGVASALNPQSTGFMAPTTFNMSMNTGTPGLNPQITGG 454
Query: 377 N--------TSQALQPQSTGFMPQNSFNQP-----------------------LNAQTTG 405
T ALQPQ+TG MPQ + P L +Q TG
Sbjct: 455 APASMQPNITGNALQPQTTGMMPQTTGMMPQTTGMMPQTSFGVNLGPQLTGGALQSQYTG 514
Query: 406 GFSSVL-NIPPPGSMPQTSFTQQAPMQTSLATGGGFLQPQATGYLPPSNFQATAPLQAQK 464
G+ SV+ P SMP SF QQ +Q+ L TG LQPQ TG+LPPSNF AT PL AQK
Sbjct: 515 GYGSVMPQQSGPASMPNLSFNQQG-LQSQL-TG---LQPQPTGFLPPSNFSATMPLTAQK 569
Query: 465 TGFGNNDLYTSANLASKFIARK-EEAITPEEKSLFYKIFETYDVEKTGNLDSATAVEIFR 523
TGFGNN++YT +N + I ++ I+ EEKSLFYKIFET+D + G LDS TAVEIFR
Sbjct: 570 TGFGNNEIYTKSNFNNNLIDNSSQDKISTEEKSLFYKIFETFDTQNKGLLDSPTAVEIFR 629
Query: 524 KSGLNRSDLEHIWNLCDTNNSGNLNKQEFALGMHLVYRRLNGEVLPNTLPPSLIPSSTKI 583
KSGLNR+DLE IWNLCD NN+G LNKQEFALGMHLVY +LNG+ +PN LP SLIPSSTK+
Sbjct: 630 KSGLNRADLEQIWNLCDINNTGQLNKQEFALGMHLVYGKLNGKPIPNVLPSSLIPSSTKL 689
Query: 584 LNTVKDQLKQGVDKNNRQPT--KEDGLRFRNNDDELLPSSRNRRKTIDQSXXXXXXXXXX 641
L+ +K+QLK +P+ K D L ++NNDD++LP+ RNRRK S
Sbjct: 690 LDNLKNQLKTEPTTTKEKPSFGKIDALSYKNNDDDVLPNYRNRRKV--YSAKNEEQSSFS 747
Query: 642 XXXXXXXREKKELLASEKLRLENDSQRK--QSENADLLRSI--ENLKSQIQALPSTSKKS 697
L ++ + ++ ++K + + A R I +N+ S + + S
Sbjct: 748 SPSAKSVNHSSSTLQTDDISVDKTVEKKTAKPKYAGFSREINLKNIASLENEIKNISNPE 807
Query: 698 PSANNAVPHDLQSRFDTLTARIPNLFKEISDVSKELVSSQLALHHLKVDHPIRGSGPNCK 757
++++P DL SRFD + A++PNLF EIS + E+ ++++ L+ K I GSGPN +
Sbjct: 808 NCYDSSIPSDLTSRFDAIIAKLPNLFNEISTIDNEITNAKIQLYRKKNPSSIIGSGPNGE 867
Query: 758 ITELDCKNARQRLTLTAGMCTLVGRPEPNYDNLEAQAQHFNEGIETIEKDDQKNQSAINN 817
ITE D K A+ R L A M L G+ + D+L + + + I+ I++++ KNQ I +
Sbjct: 868 ITENDRKKAKSRALLRARMSALTGKSTESEDSLSMEDEQQSAEIKRIQQENGKNQEIIKD 927
Query: 818 ISTWIQEISSSVQAIIHGRTPSMGLEMDKWESGIGLEPEVRDFIISWKNRRNFDNSSYNT 877
I + I +IS+S+++ + G E ++WE GIGLE VR+F+ K+ NS+ +
Sbjct: 928 IRSSISDISASLKSTMTGSNMISNQEFERWEFGIGLEDGVREFLDDLKS-----NSNKSV 982
Query: 878 AGYSNGIQISSSATYRNNARAPEEKDSYSSFQTPEERSAYV 918
S + S+ + + +P SYS F+T EER+AY+
Sbjct: 983 TESSPFVPSSTPTPVDDRSSSP----SYSQFKTAEERAAYL 1019
Score = 97.4 bits (241), Expect = 1e-19
Identities = 72/215 (33%), Positives = 99/215 (45%), Gaps = 23/215 (10%)
Query: 366 GYGAAPQTSFGNTSQALQPQSTGF-------MPQNSFNQPLNAQTTGGFSSVLNIPPPGS 418
GY A T+ ++ Q LQ Q TG+ + N QPL AQ TG + S PP
Sbjct: 149 GYYQAANTANVHSVQPLQSQGTGYYVSTPNLISSNQTQQPLQAQGTGYYQSQPQQVPP-- 206
Query: 419 MPQTSFTQQAPMQTSLATGGGFLQPQATG-YLPPSNFQATAPLQAQKTGFGNNDLYTSAN 477
PQ + + Q L+PQ TG YL P N PL+ TGF N+ N
Sbjct: 207 -PQQAQSLQP------------LKPQQTGFYLQPQNQAPLEPLKPTATGFVNSFANNGLN 253
Query: 478 LASKFIARKEEAITPEEKSLFYKIFETYDVEKTGNLDSATAVEIFRKSGLNRSDLEHIWN 537
K A + IT ++++ F +F + + + A +I +SGL S L IW
Sbjct: 254 NDIKIPAIRLSFITAQDQAKFETLFRSIVTNGSNTVSGANCRKILMRSGLPPSQLARIWT 313
Query: 538 LCDTNNSGNLNKQEFALGMHLVYRRLNGEVLPNTL 572
LCDT+ +G L EFAL MHL+ L G+ +P L
Sbjct: 314 LCDTSKAGELLFPEFALAMHLINDVLQGDTIPYEL 348
Score = 75.5 bits (184), Expect = 5e-13
Identities = 66/208 (31%), Positives = 92/208 (43%), Gaps = 24/208 (11%)
Query: 109 GFNSMMPQTSFGQPQQQMPMNTSFNQGMSTTAVNAPTGPLQPQQTGFY--SQQQPLEPLK 166
G+ S+MPQ S MP N SFNQ + + LQPQ TGF S PL
Sbjct: 515 GYGSVMPQQS---GPASMP-NLSFNQ----QGLQSQLTGLQPQPTGFLPPSNFSATMPLT 566
Query: 167 PTATGFINS-------FANTGVDNTLKIPAIRLSFITTQDQAKFEKLFRSVVTPGSNTIT 219
TGF N+ F N +DN+ + I+T++++ F K+F + T +
Sbjct: 567 AQKTGFGNNEIYTKSNFNNNLIDNSSQ------DKISTEEKSLFYKIFETFDTQNKGLLD 620
Query: 220 GDQCRNILVKSGLQPHQLAKIWTLSDTNKAGVLLFPEFALAMYLVNSVLQGDSIPYELDS 279
I KSGL L +IW L D N G L EFAL M+LV L G IP L S
Sbjct: 621 SPTAVEIFRKSGLNRADLEQIWNLCDINNTGQLNKQEFALGMHLVYGKLNGKPIPNVLPS 680
Query: 280 RTKAEVSSFVDAINFSVSND-SEVEQKP 306
+ +D + + + + ++KP
Sbjct: 681 SLIPSSTKLLDNLKNQLKTEPTTTKEKP 708
>Hs4503593 [TU] KOG0998 Synaptic vesicle protein EHS-1 and related EH domain
proteins
Length = 896
Score = 82.4 bits (202), Expect = 4e-15
Identities = 75/297 (25%), Positives = 137/297 (45%), Gaps = 48/297 (16%)
Query: 485 RKEEAITPEEKSLFYKIFETYDVEKTGNLDSATAVEIFRKSGLNRSDLEHIWNLCDTNNS 544
RK ++P EK+ + +IF D + G + EIF K+GL + L HIW+LCDT +
Sbjct: 215 RKTWVVSPAEKAKYDEIFLKTDKDMDGFVSGLEVREIFLKTGLPSTLLAHIWSLCDTKDC 274
Query: 545 GNLNKQEFALGMHLVYRRL-NGEVLPNTLPPSLIP--------------------SSTKI 583
G L+K +FAL HL+ ++L G P+ L P +IP S+ K
Sbjct: 275 GKLSKDQFALAFHLISQKLIKGIDPPHVLTPEMIPPSDRASLQKNIIGSSPVADFSAIKE 334
Query: 584 LNTVKDQL------KQGVDKNNRQPTKEDGLRFRNNDDELLPSSRNRRKTIDQSXXXXXX 637
L+T+ +++ K V+++ ++ KED ++ R ++ + L R T Q
Sbjct: 335 LDTLNNEIVDLQREKNNVEQDLKE--KEDTIKQRTSEVQDLQDEVQRENTNLQK------ 386
Query: 638 XXXXXXXXXXXREKKELLASEKLRLE---NDSQRKQSENADLLRSIE-NLKSQIQALPST 693
+E + L +K +LE + ++K +E A L+ S++ L SQ + +
Sbjct: 387 ---LQAQKQQVQELLDELDEQKAQLEEQLKEVRKKCAEEAQLISSLKAELTSQESQISTY 443
Query: 694 SKKSPSANNAVPH------DLQSRFDTLTARIPNLFKEISDVSKELVSSQLALHHLK 744
++ A + +L+ ++ A++ L + + D +E+ S Q+ L +K
Sbjct: 444 EEELAKAREELSRLQQETAELEESVESGKAQLEPLQQHLQDSQQEISSMQMKLMEMK 500
Score = 57.4 bits (137), Expect = 1e-07
Identities = 32/94 (34%), Positives = 50/94 (53%), Gaps = 1/94 (1%)
Query: 489 AITPEEKSLFYKIFETYDVEKTGNLDSATAVEIFRKSGLNRSDLEHIWNLCDTNNSGNLN 548
A+ PE+K+ + IF++ G L + S L L +W L D ++ G L+
Sbjct: 123 AVKPEDKAKYDAIFDSLS-PVNGFLSGDKVKPVLLNSKLPVDILGRVWELSDIDHDGMLD 181
Query: 549 KQEFALGMHLVYRRLNGEVLPNTLPPSLIPSSTK 582
+ EFA+ M LVY L E +P +LPP+L+P S +
Sbjct: 182 RDEFAVAMFLVYCALEKEPVPMSLPPALVPPSKR 215
Score = 55.5 bits (132), Expect = 6e-07
Identities = 28/83 (33%), Positives = 52/83 (61%), Gaps = 1/83 (1%)
Query: 195 ITTQDQAKFEKLFRSVVTPGSNTITGDQCRNILVKSGLQPHQLAKIWTLSDTNKAGVLLF 254
+ +D+AK++ +F S+ +P + ++GD+ + +L+ S L L ++W LSD + G+L
Sbjct: 124 VKPEDKAKYDAIFDSL-SPVNGFLSGDKVKPVLLNSKLPVDILGRVWELSDIDHDGMLDR 182
Query: 255 PEFALAMYLVNSVLQGDSIPYEL 277
EFA+AM+LV L+ + +P L
Sbjct: 183 DEFAVAMFLVYCALEKEPVPMSL 205
>7291848 [TU] KOG0998 Synaptic vesicle protein EHS-1 and related EH domain
proteins
Length = 668
Score = 73.9 bits (180), Expect = 2e-12
Identities = 70/287 (24%), Positives = 124/287 (42%), Gaps = 49/287 (17%)
Query: 478 LASKFIARKEEAITPEEKSLFYKIFETYDVEKTGNLDSATAVEIFRKSGLNRSDLEHIWN 537
+ + +A + +TP + F +IF D++K G + +IF KSG+ + L IW
Sbjct: 298 IGAPVMANADWVVTPADLKRFEEIFRQSDLDKDGLVSGLEVKDIFIKSGIPQRSLADIWA 357
Query: 538 LCDTNNSGNLNKQEFALGMHLVYRRLNGEVLPNTLPPSLIPSSTKILNTVKDQLKQGVDK 597
LCDTN SG L ++FAL M V R+ G P+ L +++P S + D Q V
Sbjct: 358 LCDTNQSGKLTVEQFALAMWFVERKQRGVDPPHVLNANMVPPSMRATVAGVDLQPQEV-- 415
Query: 598 NNRQPTKEDGLRFRNNDDELLPSSRNRRKTIDQSXXXXXXXXXXXXXXXXXREKKELLAS 657
+PT + N + E++ ++ E LA
Sbjct: 416 ---KPT------YSNPELEMI------------------------------SKEIEELAR 436
Query: 658 EKLRLENDSQRKQSENADLLRSIENLKSQIQALPSTSKKSPSANNAVP---HDLQSRFDT 714
E+ LE + +K+++ I+N +S++ L +T K+ + DLQ++
Sbjct: 437 ERRVLETEIAQKEAD-----VRIKNGESELDTLTATLKQLENQRGEAQKRLDDLQAQVSH 491
Query: 715 LTARIPNLFKEISDVSKELVSSQLALHHLKVDHPIRGSGPNCKITEL 761
TA + N+ +IS ++++ + H +V + N K +EL
Sbjct: 492 NTAVLANVSLDISRTNEQVTKIRDQCHMQEVTINEQEGELNAKRSEL 538
Score = 61.2 bits (147), Expect = 1e-08
Identities = 30/85 (35%), Positives = 49/85 (57%)
Query: 195 ITTQDQAKFEKLFRSVVTPGSNTITGDQCRNILVKSGLQPHQLAKIWTLSDTNKAGVLLF 254
+T D +FE++FR ++G + ++I +KSG+ LA IW L DTN++G L
Sbjct: 310 VTPADLKRFEEIFRQSDLDKDGLVSGLEVKDIFIKSGIPQRSLADIWALCDTNQSGKLTV 369
Query: 255 PEFALAMYLVNSVLQGDSIPYELDS 279
+FALAM+ V +G P+ L++
Sbjct: 370 EQFALAMWFVERKQRGVDPPHVLNA 394
Score = 53.9 bits (128), Expect = 2e-06
Identities = 32/99 (32%), Positives = 50/99 (50%), Gaps = 1/99 (1%)
Query: 478 LASKFIARKEEAITPEEKSLFYKIFETYDVEKTGNLDSATAVEIFRKSGLNRSDLEHIWN 537
+AS +A + +I ++ + ++FE+ G L + S L S L IW+
Sbjct: 117 VASGGVANGDWSIGVIDRLKYEQLFESLH-PSNGMLPGNKVKGVLMDSKLPMSILGTIWD 175
Query: 538 LCDTNNSGNLNKQEFALGMHLVYRRLNGEVLPNTLPPSL 576
L D + GNL+ EF + MHLVY+ L +P+ LPP L
Sbjct: 176 LADQDKDGNLDMHEFVVAMHLVYQTLQKRTIPSVLPPEL 214
Score = 51.6 bits (122), Expect = 8e-06
Identities = 29/76 (38%), Positives = 45/76 (59%), Gaps = 1/76 (1%)
Query: 199 DQAKFEKLFRSVVTPGSNTITGDQCRNILVKSGLQPHQLAKIWTLSDTNKAGVLLFPEFA 258
D+ K+E+LF S+ P + + G++ + +L+ S L L IW L+D +K G L EF
Sbjct: 133 DRLKYEQLFESL-HPSNGMLPGNKVKGVLMDSKLPMSILGTIWDLADQDKDGNLDMHEFV 191
Query: 259 LAMYLVNSVLQGDSIP 274
+AM+LV LQ +IP
Sbjct: 192 VAMHLVYQTLQKRTIP 207
>7297819 [U] KOG1955 Ral-GTPase effector RALBP1
Length = 903
Score = 73.6 bits (179), Expect = 2e-12
Identities = 47/131 (35%), Positives = 60/131 (44%), Gaps = 7/131 (5%)
Query: 490 ITPEEKSLFYKIFETYDVEKTGNLDSATAVEIFRKSGLNRSDLEHIWNLCDTNNSGNLNK 549
ITPE++ + K F T + G L A F KS + +L HIW LCD G L+
Sbjct: 262 ITPEQREYYNKQFRTVQRDPHGLLSGQAARNFFEKSRIPVEELRHIWQLCDVTRDGALSL 321
Query: 550 QEFALGMHLVYRRLNGEVLPNTLPPSLIPSSTKILNTVKDQLKQGVDKNNR----QPTKE 605
EF MHLV R N LP +LP L P+ +L QGV ++ Q E
Sbjct: 322 SEFTAAMHLVVLRRNNIPLPTSLPHCLHPN---VLQAAASGSGQGVTSSSSAALPQEPPE 378
Query: 606 DGLRFRNNDDE 616
L N+DDE
Sbjct: 379 ADLLHLNDDDE 389
>Hs10864047 [TU] KOG0998 Synaptic vesicle protein EHS-1 and related EH domain
proteins
Length = 864
Score = 72.8 bits (177), Expect = 3e-12
Identities = 81/342 (23%), Positives = 138/342 (39%), Gaps = 66/342 (19%)
Query: 494 EKSLFYKIFETYDVEKTGNLDSATAVEIFRKSGLNRSDLEHIWNLCDTNNSGNLNKQEFA 553
+K F +IF D++ G + EIF SGL ++ L HIW L DT +G L+K +FA
Sbjct: 275 DKMRFDEIFLKTDLDLDGYVSGQEVKEIFMHSGLTQNLLAHIWALADTRQTGKLSKDQFA 334
Query: 554 LGMHLVYRRLN-GEVLPNTLPPSLIPSSTKILNTVKDQLKQGVDKNNRQPTKE-DGLRFR 611
L M+ + ++++ G P L P ++P S ++ G D + + E G++
Sbjct: 335 LAMYFIQQKVSKGIDPPQVLSPDMVPPS--------ERGTPGPDSSGSLGSGEFTGVKEL 386
Query: 612 NNDDELLPSSRNRRKTIDQSXXXXXXXXXXXXXXXXXREKKELL---ASEKLRLENDSQR 668
++ + + + + +++Q REK+E + SE L+ND R
Sbjct: 387 DDISQEIAQLQREKYSLEQD----------------IREKEEAIRQKTSEVQELQNDLDR 430
Query: 669 KQSENADLLRSIENLKSQIQALPSTSKKSPSANNAVPHDLQSRFDTLTARIPNLFKEISD 728
+ S S++ L++Q Q D Q R D + + L +SD
Sbjct: 431 ETS-------SLQELEAQKQ------------------DAQDRLDEMDQQKAKLRDMLSD 465
Query: 729 VSKELVSSQLALHHLKVDHPIRGSGPNCKITELDCKNARQRLTLTAGMCTLVGRPEPNYD 788
V ++ + LK I+ + K E D A+ L R +
Sbjct: 466 VRQKCQDETQMISSLKTQ--IQSQESDLKSQEDDLNRAKSEL----------NRLQQEET 513
Query: 789 NLEAQAQHFNEGIETIEKDDQKNQSAINNISTWIQEISSSVQ 830
LE Q +ETI K + Q IN + + ++ S Q
Sbjct: 514 QLEQSIQAGRVQLETIIKSLKSTQDEINQARSKLSQLHESRQ 555
Score = 67.8 bits (164), Expect = 1e-10
Identities = 38/94 (40%), Positives = 53/94 (55%), Gaps = 1/94 (1%)
Query: 489 AITPEEKSLFYKIFETYDVEKTGNLDSATAVEIFRKSGLNRSDLEHIWNLCDTNNSGNLN 548
A+ EEK+ F IFE+ + G L + S L L +W+L D + G+L+
Sbjct: 122 AVRVEEKAKFDGIFESL-LPINGLLSGDKVKPVLMNSKLPLDVLGRVWDLSDIDKDGHLD 180
Query: 549 KQEFALGMHLVYRRLNGEVLPNTLPPSLIPSSTK 582
+ EFA+ MHLVYR L E +P+ LPPSLIP S +
Sbjct: 181 RDEFAVAMHLVYRALEKEPVPSALPPSLIPPSKR 214
Score = 55.5 bits (132), Expect = 6e-07
Identities = 29/83 (34%), Positives = 52/83 (61%), Gaps = 1/83 (1%)
Query: 195 ITTQDQAKFEKLFRSVVTPGSNTITGDQCRNILVKSGLQPHQLAKIWTLSDTNKAGVLLF 254
+ +++AKF+ +F S++ P + ++GD+ + +L+ S L L ++W LSD +K G L
Sbjct: 123 VRVEEKAKFDGIFESLL-PINGLLSGDKVKPVLMNSKLPLDVLGRVWDLSDIDKDGHLDR 181
Query: 255 PEFALAMYLVNSVLQGDSIPYEL 277
EFA+AM+LV L+ + +P L
Sbjct: 182 DEFAVAMHLVYRALEKEPVPSAL 204
>YBL047c [TU] KOG0998 Synaptic vesicle protein EHS-1 and related EH domain
proteins
Length = 1381
Score = 70.5 bits (171), Expect = 2e-11
Identities = 41/126 (32%), Positives = 66/126 (51%), Gaps = 3/126 (2%)
Query: 457 TAPLQAQKTGFGNNDLYTSANLASKFI---ARKEEAITPEEKSLFYKIFETYDVEKTGNL 513
T PL A TG + +++ + S A + +++ E+K F IF++ D + G+L
Sbjct: 237 TTPLSANSTGVSSLTRHSTISRLSTGAFSNAASDWSLSFEKKQQFDAIFDSLDKQHAGSL 296
Query: 514 DSATAVEIFRKSGLNRSDLEHIWNLCDTNNSGNLNKQEFALGMHLVYRRLNGEVLPNTLP 573
SA V F S LN+ L IW+L D +N+ K EFA+ M L+ ++ G LP+ +P
Sbjct: 297 SSAVLVPFFLSSRLNQETLATIWDLADIHNNAEFTKLEFAIAMFLIQKKNAGVELPDVIP 356
Query: 574 PSLIPS 579
L+ S
Sbjct: 357 NELLQS 362
Score = 60.5 bits (145), Expect = 2e-08
Identities = 43/130 (33%), Positives = 64/130 (49%), Gaps = 21/130 (16%)
Query: 142 NAPTGPLQ-------PQQTGFYSQQQPLEPLKPTATGFINSFANTGVDNTLKIPAIRLSF 194
NAP P+ P Q +S Q P++ S + TG N IPA+
Sbjct: 84 NAPNQPISAALYESTPTQLASFSINQNPAPMQ--------SGSATGNTNNTDIPAL---- 131
Query: 195 ITTQDQAKFEKLFRSVVTPGSNTITGDQCRNILVKSGLQPHQLAKIWTLSDTNKAGVLLF 254
++ D AKF +LF G+ T+ GD+ ++I +K+ L L +IW L D + +GVL
Sbjct: 132 -SSNDIAKFSQLFDRTAK-GAQTVAGDKAKDIFLKARLPNQTLGEIWALCDRDASGVLDK 189
Query: 255 PEFALAMYLV 264
EF +AMYL+
Sbjct: 190 SEFIMAMYLI 199
>Hs4504797_1 [TU] KOG1029 Endocytic adaptor protein intersectin
Length = 1221
Score = 70.5 bits (171), Expect = 2e-11
Identities = 66/220 (30%), Positives = 98/220 (44%), Gaps = 27/220 (12%)
Query: 109 GFNSMMPQTSFGQPQQQMPMNTSFNQGMSTTAVNA-PTGPLQPQQTGFYSQQQPLEPLK- 166
G SM P T+ +PM + GMS T V++ PT + P G QPL
Sbjct: 119 GIASMPPLTAVAP----VPMGSIPVVGMSPTLVSSVPTAAVPPLANGAPPVIQPLPAFAH 174
Query: 167 PTAT-GFINSFANTGVDNTLK-------------IPAIRLSFITTQDQAKFEKLFRSVVT 212
P AT +SF+ +G + L +P + + + K+ +LF S
Sbjct: 175 PAATLPKSSSFSRSGPGSQLNTKLQKAQSFDVASVPPVAEWAVPQSSRLKYRQLFNSHDK 234
Query: 213 PGSNTITGDQCRNILVKSGLQPHQLAKIWTLSDTNKAGVLLFPEFALAMYLVNSVLQGDS 272
S +TG Q R IL++S L QLA IW LSD ++ G L EF LAM+L++ + G
Sbjct: 235 TMSGHLTGPQARTILMQSSLPQAQLASIWNLSDIDQDGKLTAEEFILAMHLIDVAMSGQP 294
Query: 273 IP------YELDSRTKAEVSSFVDAINFSVSNDSEVEQKP 306
+P Y S + S + I+ S S D + ++P
Sbjct: 295 LPPVLPPEYIPPSFRRVRSGSGISVIS-STSVDQRLPEEP 333
Score = 66.2 bits (160), Expect = 3e-10
Identities = 35/94 (37%), Positives = 51/94 (54%), Gaps = 1/94 (1%)
Query: 488 EAITPEEKSLFYK-IFETYDVEKTGNLDSATAVEIFRKSGLNRSDLEHIWNLCDTNNSGN 546
E P+ L Y+ +F ++D +G+L A I +S L ++ L IWNL D + G
Sbjct: 214 EWAVPQSSRLKYRQLFNSHDKTMSGHLTGPQARTILMQSSLPQAQLASIWNLSDIDQDGK 273
Query: 547 LNKQEFALGMHLVYRRLNGEVLPNTLPPSLIPSS 580
L +EF L MHL+ ++G+ LP LPP IP S
Sbjct: 274 LTAEEFILAMHLIDVAMSGQPLPPVLPPEYIPPS 307
Score = 63.2 bits (152), Expect = 3e-09
Identities = 39/102 (38%), Positives = 56/102 (54%), Gaps = 1/102 (0%)
Query: 195 ITTQDQAKFEKLFRSVVTPGSNTITGDQCRNILVKSGLQPHQLAKIWTLSDTNKAGVLLF 254
IT +++AK ++ F S+ P S ITGDQ RN +SGL LA+IW L+D N G +
Sbjct: 17 ITVEERAKHDQQFHSL-KPISGFITGDQARNFFFQSGLPQPVLAQIWALADMNNDGRMDQ 75
Query: 255 PEFALAMYLVNSVLQGDSIPYELDSRTKAEVSSFVDAINFSV 296
EF++AM L+ LQG +P L K + + A F +
Sbjct: 76 VEFSIAMKLIKLKLQGYQLPSALPPVMKQQPVAISSAPPFGM 117
Score = 52.8 bits (125), Expect = 4e-06
Identities = 31/86 (36%), Positives = 47/86 (54%), Gaps = 1/86 (1%)
Query: 489 AITPEEKSLFYKIFETYDVEKTGNLDSATAVEIFRKSGLNRSDLEHIWNLCDTNNSGNLN 548
AIT EE++ + F + +G + A F +SGL + L IW L D NN G ++
Sbjct: 16 AITVEERAKHDQQFHSLK-PISGFITGDQARNFFFQSGLPQPVLAQIWALADMNNDGRMD 74
Query: 549 KQEFALGMHLVYRRLNGEVLPNTLPP 574
+ EF++ M L+ +L G LP+ LPP
Sbjct: 75 QVEFSIAMKLIKLKLQGYQLPSALPP 100
>Hs13994296 [U] KOG1955 Ral-GTPase effector RALBP1
Length = 744
Score = 70.1 bits (170), Expect = 2e-11
Identities = 57/205 (27%), Positives = 81/205 (38%), Gaps = 21/205 (10%)
Query: 374 SFGNTSQALQPQSTGFMPQNSFNQPLNAQTTGGFSSVLNIPPPGSMPQTSFTQQAPMQTS 433
S GN+ + L + P F + + + G + PPP SF P T
Sbjct: 134 SGGNSERPLAGPGPFWSP---FGEAQSGSSAGDAVWSGHSPPPPQENWVSFADTPPTSTL 190
Query: 434 LATGGGFLQPQATGYLPPSNFQATAPLQAQKTGFGNNDLYTSANLASKFIARKEEAITPE 493
L +Q Q T S AT ++ ++ +D + IT E
Sbjct: 191 LTMHPASVQDQTTVRTVAS---ATTAIEIRRQSSSYDDPWK---------------ITDE 232
Query: 494 EKSLFYKIFETYDVEKTGNLDSATAVEIFRKSGLNRSDLEHIWNLCDTNNSGNLNKQEFA 553
++ + F+T + G + + A E F KS L +L HIW L D + G L EF
Sbjct: 233 QRQYYVNQFKTIQPDLNGFIPGSAAKEFFTKSKLPILELSHIWELSDFDKDGALTLDEFC 292
Query: 554 LGMHLVYRRLNGEVLPNTLPPSLIP 578
HLV R NG LP LP SL+P
Sbjct: 293 AAFHLVVARKNGYDLPEKLPESLMP 317
>CE02903 [TU] KOG0998 Synaptic vesicle protein EHS-1 and related EH domain
proteins
Length = 751
Score = 65.9 bits (159), Expect = 4e-10
Identities = 35/83 (42%), Positives = 53/83 (63%), Gaps = 1/83 (1%)
Query: 195 ITTQDQAKFEKLFRSVVTPGSNTITGDQCRNILVKSGLQPHQLAKIWTLSDTNKAGVLLF 254
IT DQAK++ +F+S+ P + ++G R +L+ SGL H LA+IW LSD +K G L
Sbjct: 113 ITPTDQAKYDSIFQSL-NPVNGKLSGAHVRPVLMNSGLDAHALARIWELSDQDKDGNLDR 171
Query: 255 PEFALAMYLVNSVLQGDSIPYEL 277
E ++A++LV LQ D +P +L
Sbjct: 172 IEMSVALHLVYRSLQSDPVPAQL 194
Score = 63.2 bits (152), Expect = 3e-09
Identities = 33/91 (36%), Positives = 51/91 (55%), Gaps = 1/91 (1%)
Query: 490 ITPEEKSLFYKIFETYDVEKTGNLDSATAVEIFRKSGLNRSDLEHIWNLCDTNNSGNLNK 549
ITP +++ + IF++ + G L A + SGL+ L IW L D + GNL++
Sbjct: 113 ITPTDQAKYDSIFQSLN-PVNGKLSGAHVRPVLMNSGLDAHALARIWELSDQDKDGNLDR 171
Query: 550 QEFALGMHLVYRRLNGEVLPNTLPPSLIPSS 580
E ++ +HLVYR L + +P LPP+LI S
Sbjct: 172 IEMSVALHLVYRSLQSDPVPAQLPPNLIHPS 202
Score = 56.2 bits (134), Expect = 3e-07
Identities = 56/244 (22%), Positives = 91/244 (36%), Gaps = 17/244 (6%)
Query: 502 FETYDVEKTGNLDSATAVEIFRKSGLNRSDLEHIWNLCDTNNSGNLNKQEFALGMHLVYR 561
F D K G +D +GL+ L H+W L D G LN ++FAL MHL+
Sbjct: 302 FAQTDTNKDGLVDGMDMRAPMMTTGLSAQILAHVWALADIKKCGQLNLEQFALTMHLLDM 361
Query: 562 RLNGEVLPNTLPPSLIPSSTK-----------ILNTVKDQLKQGVDKNNRQPTKEDGLRF 610
GE +P+ LP LIP S + + QL + ++ + +
Sbjct: 362 AKRGESIPSELPLHLIPPSFRPPTEPSALHHPAQSVSTPQLPEATSMEIKEALEGENEEM 421
Query: 611 RNNDDELLPSSRNRRKTIDQSXXXXXXXXXXXXXXXXXRE-KKELLASEKLRLENDSQRK 669
+ E + S RKT +++ + + L S +LE
Sbjct: 422 KQL-AESIQSMLVERKTAEEAVLQLEADMTIKNSSIKNLQVELATLESTVKQLERQKGEA 480
Query: 670 QSENADLLRSIENLKSQIQALPSTSKKSPSANNAVPHDLQSRFDTLTARIPNLFKEISDV 729
AD IE L+S +A T + + + D ++ D N KE+ ++
Sbjct: 481 TRRLADYDTQIEQLESACKAQKETKEDTEKRMQQIDEDAKNAEDCKA----NDEKEMEEL 536
Query: 730 SKEL 733
KE+
Sbjct: 537 KKEI 540
>Hs11128045_1 [TU] KOG1029 Endocytic adaptor protein intersectin
Length = 1177
Score = 65.9 bits (159), Expect = 4e-10
Identities = 35/83 (42%), Positives = 51/83 (61%), Gaps = 1/83 (1%)
Query: 195 ITTQDQAKFEKLFRSVVTPGSNTITGDQCRNILVKSGLQPHQLAKIWTLSDTNKAGVLLF 254
IT++++ K ++ F ++ P ITGDQ RN ++SGL LA+IW LSD NK G +
Sbjct: 29 ITSEERTKHDRQFDNL-KPSGGYITGDQARNFFLQSGLPAPVLAEIWALSDLNKDGKMDQ 87
Query: 255 PEFALAMYLVNSVLQGDSIPYEL 277
EF++AM L+ LQG +P L
Sbjct: 88 QEFSIAMKLIKLKLQGQQLPVVL 110
Score = 64.3 bits (155), Expect = 1e-09
Identities = 80/328 (24%), Positives = 127/328 (38%), Gaps = 36/328 (10%)
Query: 388 GFMPQNSFNQPL---------NAQTTGGFSSVLNIPPP-------GSMPQ--TSFTQQAP 429
G MP S QPL ++ T+G L +P P S+P S Q P
Sbjct: 131 GSMPNLSIPQPLPPAAPITSLSSATSGTNLPPLMMPTPLVPSVSTSSLPNGTASLIQPLP 190
Query: 430 MQTSLATGGGFLQPQATGY-LPPSNFQATAPLQAQKT---GFGNNDLYTSANLASKFIAR 485
+ S +T P + Y L F + +AQ G ++ T++ +
Sbjct: 191 IPYSSST-----LPHGSSYSLMMGGFGGASIQKAQSLIDLGSSSSTSSTASLSGNSPKTG 245
Query: 486 KEEAITPEEKSLFYKI-FETYDVEKTGNLDSATAVEIFRKSGLNRSDLEHIWNLCDTNNS 544
E P+ L Y+ F T D +G L A +S L+++ L IW L D +
Sbjct: 246 TSEWAVPQPTRLKYRQKFNTLDKSMSGYLSGFQARNALLQSNLSQTQLATIWTLADVDGD 305
Query: 545 GNLNKQEFALGMHLVYRRLNGEVLPNTLPPSLIPSS---TKILNTVKDQLKQGVDKNNRQ 601
G L +EF L MHL G+ LP TLPP L+P S K ++++ L +
Sbjct: 306 GQLKAEEFILAMHLTDMAKAGQPLPLTLPPELVPPSFRGGKQIDSINGTLPSYQKMQEEE 365
Query: 602 PTKEDGLRFRN----NDDELLPSSRNRRKTIDQSXXXXXXXXXXXXXXXXXREKKELLAS 657
P K+ + F + N + RR+ + + R+++EL
Sbjct: 366 PQKKLPVTFEDKRKANYERGNMELEKRRQALMEQQQREAERKAQKEKEEWERKQRELQEQ 425
Query: 658 E-KLRLENDSQRKQSENADLLRSIENLK 684
E K +LE + + ++ + R E K
Sbjct: 426 EWKKQLELEKRLEKQRELERQREEERRK 453
Score = 53.9 bits (128), Expect = 2e-06
Identities = 31/86 (36%), Positives = 45/86 (52%), Gaps = 1/86 (1%)
Query: 489 AITPEEKSLFYKIFETYDVEKTGNLDSATAVEIFRKSGLNRSDLEHIWNLCDTNNSGNLN 548
AIT EE++ + F+ G + A F +SGL L IW L D N G ++
Sbjct: 28 AITSEERTKHDRQFDNLK-PSGGYITGDQARNFFLQSGLPAPVLAEIWALSDLNKDGKMD 86
Query: 549 KQEFALGMHLVYRRLNGEVLPNTLPP 574
+QEF++ M L+ +L G+ LP LPP
Sbjct: 87 QQEFSIAMKLIKLKLQGQQLPVVLPP 112
Score = 53.5 bits (127), Expect = 2e-06
Identities = 36/119 (30%), Positives = 56/119 (46%), Gaps = 8/119 (6%)
Query: 202 KFEKLFRSVVTPGSNTITGDQCRNILVKSGLQPHQLAKIWTLSDTNKAGVLLFPEFALAM 261
K+ + F ++ S ++G Q RN L++S L QLA IWTL+D + G L EF LAM
Sbjct: 258 KYRQKFNTLDKSMSGYLSGFQARNALLQSNLSQTQLATIWTLADVDGDGQLKAEEFILAM 317
Query: 262 YLVNSVLQGDSIPYELDSR---TKAEVSSFVDAIN-----FSVSNDSEVEQKPKTPFDD 312
+L + G +P L +D+IN + + E ++K F+D
Sbjct: 318 HLTDMAKAGQPLPLTLPPELVPPSFRGGKQIDSINGTLPSYQKMQEEEPQKKLPVTFED 376
>SPBC83.01 [TU] KOG0998 Synaptic vesicle protein EHS-1 and related EH domain
proteins
Length = 884
Score = 65.5 bits (158), Expect = 5e-10
Identities = 32/83 (38%), Positives = 49/83 (58%)
Query: 490 ITPEEKSLFYKIFETYDVEKTGNLDSATAVEIFRKSGLNRSDLEHIWNLCDTNNSGNLNK 549
ITPE++S FY++F D E G + AV F S L+ +L IW+ DT + G ++K
Sbjct: 296 ITPEDRSNFYQLFSKIDNENKGYIVGGEAVPFFMASHLDSEELARIWDTVDTQDRGYIDK 355
Query: 550 QEFALGMHLVYRRLNGEVLPNTL 572
EFA+ M ++ RL+G+ L + L
Sbjct: 356 DEFAVAMEIIKLRLSGKSLASIL 378
Score = 52.8 bits (125), Expect = 4e-06
Identities = 40/153 (26%), Positives = 69/153 (44%), Gaps = 14/153 (9%)
Query: 128 MNTSFNQGMSTTAVNAPTGPLQPQQTGFYSQQQPLEPLKPTATGFINSFANTGVDNTLKI 187
MNT+ QG++ ++ T L QQ+ ++ L+ + ++ A + VDN
Sbjct: 229 MNTNIEQGVTQPSL-VNTEQLSHQQSISSTKSSKLDEISA------DNNAQSAVDNKYSS 281
Query: 188 PAIRL-------SFITTQDQAKFEKLFRSVVTPGSNTITGDQCRNILVKSGLQPHQLAKI 240
P + + IT +D++ F +LF + I G + + S L +LA+I
Sbjct: 282 PPQTIDPQANIKALITPEDRSNFYQLFSKIDNENKGYIVGGEAVPFFMASHLDSEELARI 341
Query: 241 WTLSDTNKAGVLLFPEFALAMYLVNSVLQGDSI 273
W DT G + EFA+AM ++ L G S+
Sbjct: 342 WDTVDTQDRGYIDKDEFAVAMEIIKLRLSGKSL 374
Score = 51.6 bits (122), Expect = 8e-06
Identities = 36/123 (29%), Positives = 61/123 (49%), Gaps = 7/123 (5%)
Query: 490 ITPEEKSLFYKIFETY-----DVEKTGNLDSATAVEIFRKSGLNRSDLEHIWNLCDTNNS 544
I P+E+S + K F D + G + S+ A I KS L+ + L IWNL D+ +
Sbjct: 125 INPDERSEYEKEFRENLRGHEDSARPGCMPSSIAKPILLKSSLHYAVLAQIWNLADSAHV 184
Query: 545 GNLNKQEFALGMHLV--YRRLNGEVLPNTLPPSLIPSSTKILNTVKDQLKQGVDKNNRQP 602
G L ++ + HLV ++ N LP +LP +I S+ + ++QGV + +
Sbjct: 185 GYLEMYQYVIARHLVAICKQYNLIHLPRSLPADVIESAKSETPAMNTNIEQGVTQPSLVN 244
Query: 603 TKE 605
T++
Sbjct: 245 TEQ 247
>SPBC800.10c [TU] KOG0998 Synaptic vesicle protein EHS-1 and related EH domain
proteins
Length = 1116
Score = 62.8 bits (151), Expect = 4e-09
Identities = 32/100 (32%), Positives = 53/100 (53%)
Query: 489 AITPEEKSLFYKIFETYDVEKTGNLDSATAVEIFRKSGLNRSDLEHIWNLCDTNNSGNLN 548
AI ++ + F ++F D G + + A F S L L IW+L DTN++G LN
Sbjct: 254 AIPSQDLTSFCQLFSNVDKAHKGYVSGSEAYSFFLASKLPEDVLAQIWDLSDTNSNGKLN 313
Query: 549 KQEFALGMHLVYRRLNGEVLPNTLPPSLIPSSTKILNTVK 588
EF + ++L+ +L+G+ LP LP S++ S ++ K
Sbjct: 314 IGEFCISLYLIKLKLSGKELPKVLPSSMLSSVAPLMQKSK 353
Score = 56.2 bits (134), Expect = 3e-07
Identities = 40/133 (30%), Positives = 62/133 (46%), Gaps = 6/133 (4%)
Query: 195 ITTQDQAKFEKLFRSVVTPGSNTITGDQCRNILVKSGLQPHQLAKIWTLSDTNKAGVLLF 254
I +QD F +LF +V ++G + + + S L LA+IW LSDTN G L
Sbjct: 255 IPSQDLTSFCQLFSNVDKAHKGYVSGSEAYSFFLASKLPEDVLAQIWDLSDTNSNGKLNI 314
Query: 255 PEFALAMYLVNSVLQGDSIPYELDSRTKAEVSSFVD-AINFSVSNDSEVEQKPKTPFDDL 313
EF +++YL+ L G +P L S + V+ + + + S S V +P +
Sbjct: 315 GEFCISLYLIKLKLSGKELPKVLPSSMLSSVAPLMQKSKSVPTSIPSVVPANISSPNPNP 374
Query: 314 TAGISMMQPQPTG 326
T + P PTG
Sbjct: 375 T-----LAPNPTG 382
Score = 54.3 bits (129), Expect = 1e-06
Identities = 30/96 (31%), Positives = 49/96 (50%), Gaps = 4/96 (4%)
Query: 195 ITTQDQAKFEKLFRSVVTPGSNTITGDQCRNILVKSGLQPHQLAKIWTLSDTNKAGVLLF 254
++ ++Q F++LF+ ITG++ L KSGL P L +IW ++D G L F
Sbjct: 5 LSAEEQTAFDQLFKIADKQDIGVITGEEAVPFLEKSGLAPQVLGQIWQIADAENRGFLTF 64
Query: 255 PEFALAMYLVNSVLQGDSIPYELDSRTKAEVSSFVD 290
F +AM LV L + +P+ D + ++ F D
Sbjct: 65 SGFVIAMRLV--ALAQEKLPF--DYKKSGKIPYFAD 96
Score = 52.0 bits (123), Expect = 6e-06
Identities = 31/93 (33%), Positives = 51/93 (54%), Gaps = 3/93 (3%)
Query: 490 ITPEEKSLFYKIFETYDVEKTGNLDSATAVEIFRKSGLNRSDLEHIWNLCDTNNSGNLNK 549
I+ +E + + ++F T G +D A IF ++ L+ L +WNL DT+ G L+
Sbjct: 130 ISSDEMTRYQQMFTTV-CPTDGLMDGDRASSIFGRAPLSTEILARVWNLVDTHKRGALDI 188
Query: 550 QEFALGMHLVYRRLNGEVL--PNTLPPSLIPSS 580
+EF GMH++ LNG + P ++ PS I S+
Sbjct: 189 REFNTGMHIINLLLNGSLKSPPVSISPSFIASA 221
>SPBC11G11.02c [TU] KOG0998 Synaptic vesicle protein EHS-1 and related EH domain
proteins
Length = 375
Score = 62.4 bits (150), Expect = 5e-09
Identities = 34/107 (31%), Positives = 60/107 (55%), Gaps = 3/107 (2%)
Query: 492 PEEKSLFYKIFETYDVEKTGNLDSATAVEIFRKSGLNRSDLEHIWNLCDTNNSGNLNKQE 551
P+EK+ +++IF + E G L + A + R S L+ LE IW+L D ++ G + E
Sbjct: 3 PQEKNKYWEIFRGLNPEN-GYLSGSKAAGVLRSSKLSSDKLEKIWDLADIDDDGMFDFDE 61
Query: 552 FALGMHLVYRRLNG--EVLPNTLPPSLIPSSTKILNTVKDQLKQGVD 596
FA+ M + + +NG + +P+ +P +L+ +S K L +D L+ D
Sbjct: 62 FAIAMKITFDLINGVYKTVPDRVPEALVSTSKKHLVAARDALRGNDD 108
>Hs4758944 [U] KOG1955 Ral-GTPase effector RALBP1
Length = 521
Score = 61.6 bits (148), Expect = 8e-09
Identities = 51/179 (28%), Positives = 75/179 (41%), Gaps = 23/179 (12%)
Query: 415 PPGSMPQTSFTQQAPMQTSLATGGGFLQPQATGYLPPSNFQATAPLQ----AQKTGFGNN 470
PP S P Q+ P L+ G L+ A + P+ ++A PL + G G
Sbjct: 57 PPSSPPHY---QRVP----LSHGYSKLRSSAE-QMHPAPYEARQPLVQPEGSSSGGPGTK 108
Query: 471 DLYTSANLASKFIARKEEA-----------ITPEEKSLFYKIFETYDVEKTGNLDSATAV 519
L A+L F +E IT E++ + F + + + + + A
Sbjct: 109 PLRHQASLIRSFSVERELQDNSSYPDEPWRITEEQREYYVNQFRSLQPDPSSFISGSVAK 168
Query: 520 EIFRKSGLNRSDLEHIWNLCDTNNSGNLNKQEFALGMHLVYRRLNGEVLPNTLPPSLIP 578
F KS L+ +L +IW L D + G L EF HL+ R NG LP LPP+L P
Sbjct: 169 NFFTKSKLSIPELSYIWELSDADCDGALTLPEFCAAFHLIVARKNGYPLPEGLPPTLQP 227
>At1g20760 [TU] KOG0998 Synaptic vesicle protein EHS-1 and related EH domain
proteins
Length = 1019
Score = 60.5 bits (145), Expect = 2e-08
Identities = 53/214 (24%), Positives = 81/214 (37%), Gaps = 36/214 (16%)
Query: 371 PQTSFGNTSQALQPQSTGFMPQNSFNQPLNAQTTGGF---SSVLNIPPPGSMPQTSFTQQ 427
P S + S A+ P S G P N + Q+T + L P P + Q + + Q
Sbjct: 266 PTLSNSSISSAIVPTSAGIQPPTKPNALDSLQSTFSMLPSGNQLQQPRPAASSQPAVSSQ 325
Query: 428 APMQTSLATGGGFLQPQATGYLPPSNFQATAPLQAQKTGFGNNDLYTSANLASKFIARKE 487
P + LPP + A T GNN
Sbjct: 326 GP----------------SSGLPPGS----AVGSGHSTPAGNNQ-------------PPW 352
Query: 488 EAITPEEKSLFYKIFETYDVEKTGNLDSATAVEIFRKSGLNRSDLEHIWNLCDTNNSGNL 547
+ P + + K+F D +K G + A +F L R L+H+W L D +N L
Sbjct: 353 PKMKPSDVQKYTKVFMEVDSDKDGKITGEQARNLFLSWRLPREVLKHVWELSDQDNDTML 412
Query: 548 NKQEFALGMHLVYRRLNGEVLPNTLPPSLIPSST 581
+ +EF + ++L+ R G LP LP S++ T
Sbjct: 413 SLREFCISLYLMERYREGRPLPTALPSSIMFDET 446
>Hs21264315 [TU] KOG1954 Endocytosis/signaling protein EHD1
Length = 541
Score = 59.7 bits (143), Expect = 3e-08
Identities = 34/97 (35%), Positives = 54/97 (55%), Gaps = 1/97 (1%)
Query: 484 ARKEEAITPEEKSLFYKIFETYDVEKTGNLDSATAVEIFRKSGLNRSDLEHIWNLCDTNN 543
A +EE + ++K ++ ++F T G + A + S L S L IW L D +
Sbjct: 437 ADEEEWVVAKDKPVYDELFYTLS-PINGKISGVNAKKEMVTSKLPNSVLGKIWKLADCDC 495
Query: 544 SGNLNKQEFALGMHLVYRRLNGEVLPNTLPPSLIPSS 580
G L+++EFAL HL+ +L+G LP++LPP L+P S
Sbjct: 496 DGMLDEEEFALAKHLIKIKLDGYELPSSLPPHLVPPS 532
>7298751 [TU] KOG1029 Endocytic adaptor protein intersectin
Length = 1097
Score = 59.7 bits (143), Expect = 3e-08
Identities = 58/244 (23%), Positives = 101/244 (40%), Gaps = 23/244 (9%)
Query: 487 EEAITPEEKSLFYKIFETYDVEKTGNLDSATAVEIFRKSGLNRSDLEHIWNLCDTNNSGN 546
E A+ +K + ++F D ++G L + A + +S L + L IW L D + G
Sbjct: 184 EWAVQAAQKRKYTQVFNANDRTRSGYLTGSQARGVLVQSKLPQVTLAQIWTLSDIDGDGR 243
Query: 547 LNKQEFALGMHLVYRRLNGEVLPNTLPPSLIPSSTKILNTVKDQLKQGVDKNNRQP---- 602
LN EF L M L + + GE +P TLP +P + + + + + V + QP
Sbjct: 244 LNCDEFILAMFLCEKAMAGEKIPVTLPQEWVPPNLRKIKSRPGSVSGVVSRPGSQPASRH 303
Query: 603 ---TKEDGLRFRNNDDEL-LP---SSRNRRK--------TIDQSXXXXXXXXXXXXXXXX 647
+ + G+ + D LP S ++RK +D+
Sbjct: 304 ASVSSQSGVGVVDADPTAGLPGQTSFEDKRKENYVKGQAELDRRRKIMEDQQRKEREERE 363
Query: 648 XREKKELLASEKLRLENDSQRKQSENADLLRSIENLKSQIQALPSTSKKSPSANNAVPHD 707
+E++E EK RLE ++RKQ E +L R ++ + K+ A A +
Sbjct: 364 RKEREEADKREKARLE--AERKQQE--ELERQLQRQREIEMEKEEQRKRELEAKEAARKE 419
Query: 708 LQSR 711
L+ +
Sbjct: 420 LEKQ 423
Score = 56.6 bits (135), Expect = 3e-07
Identities = 31/83 (37%), Positives = 45/83 (53%)
Query: 195 ITTQDQAKFEKLFRSVVTPGSNTITGDQCRNILVKSGLQPHQLAKIWTLSDTNKAGVLLF 254
+ + K+ ++F + S +TG Q R +LV+S L LA+IWTLSD + G L
Sbjct: 187 VQAAQKRKYTQVFNANDRTRSGYLTGSQARGVLVQSKLPQVTLAQIWTLSDIDGDGRLNC 246
Query: 255 PEFALAMYLVNSVLQGDSIPYEL 277
EF LAM+L + G+ IP L
Sbjct: 247 DEFILAMFLCEKAMAGEKIPVTL 269
Score = 54.7 bits (130), Expect = 1e-06
Identities = 32/93 (34%), Positives = 48/93 (51%), Gaps = 1/93 (1%)
Query: 489 AITPEEKSLFYKIFETYDVEKTGNLDSATAVEIFRKSGLNRSDLEHIWNLCDTNNSGNLN 548
A+TP E+ + + F + G + A A F +S L L IW L DT++ G +N
Sbjct: 9 AVTPRERLKYQEQFRALQPQ-AGFVTGAQAKGFFLQSQLPPLILGQIWALADTDSDGKMN 67
Query: 549 KQEFALGMHLVYRRLNGEVLPNTLPPSLIPSST 581
EF++ L+ +L G +P LPPSL+ S T
Sbjct: 68 INEFSIACKLINLKLRGMDVPKVLPPSLLSSLT 100
Score = 54.3 bits (129), Expect = 1e-06
Identities = 33/128 (25%), Positives = 63/128 (48%), Gaps = 4/128 (3%)
Query: 195 ITTQDQAKFEKLFRSVVTPGSNTITGDQCRNILVKSGLQPHQLAKIWTLSDTNKAGVLLF 254
+T +++ K+++ FR++ P + +TG Q + ++S L P L +IW L+DT+ G +
Sbjct: 10 VTPRERLKYQEQFRAL-QPQAGFVTGAQAKGFFLQSQLPPLILGQIWALADTDSDGKMNI 68
Query: 255 PEFALAMYLVNSVLQGDSIPYELDSRTKAEVSSFVDAINFSVSNDSEVEQKPKTPFDDLT 314
EF++A L+N L+G +P L + +SS + S P P +
Sbjct: 69 NEFSIACKLINLKLRGMDVPKVL---PPSLLSSLTGDVPSMTPRGSTSSLSPLDPLKGIV 125
Query: 315 AGISMMQP 322
++ + P
Sbjct: 126 PAVAPVVP 133
>Hs5803009 [TU] KOG1954 Endocytosis/signaling protein EHD1
Length = 534
Score = 57.8 bits (138), Expect = 1e-07
Identities = 33/95 (34%), Positives = 49/95 (50%), Gaps = 1/95 (1%)
Query: 488 EAITPEEKSLFYKIFETYDVEKTGNLDSATAVEIFRKSGLNRSDLEHIWNLCDTNNSGNL 547
E + ++K + +IF T G + A + KS L ++L IW L D + G L
Sbjct: 438 EWVVGKDKPSYDEIFYTLS-PVNGKITGANVKKEMVKSKLPNTELGKIWKLADVDKDGLL 496
Query: 548 NKQEFALGMHLVYRRLNGEVLPNTLPPSLIPSSTK 582
+ +EFAL HL+ +L G LP LPP L+P S +
Sbjct: 497 DDEEFALANHLIKVKLEGHELPADLPPHLVPPSKR 531
Score = 55.8 bits (133), Expect = 4e-07
Identities = 29/86 (33%), Positives = 53/86 (60%), Gaps = 1/86 (1%)
Query: 192 LSFITTQDQAKFEKLFRSVVTPGSNTITGDQCRNILVKSGLQPHQLAKIWTLSDTNKAGV 251
+ ++ +D+ ++++F ++ +P + ITG + +VKS L +L KIW L+D +K G+
Sbjct: 437 VEWVVGKDKPSYDEIFYTL-SPVNGKITGANVKKEMVKSKLPNTELGKIWKLADVDKDGL 495
Query: 252 LLFPEFALAMYLVNSVLQGDSIPYEL 277
L EFALA +L+ L+G +P +L
Sbjct: 496 LDDEEFALANHLIKVKLEGHELPADL 521
>Hs18578080 [TU] KOG1954 Endocytosis/signaling protein EHD1
Length = 534
Score = 57.8 bits (138), Expect = 1e-07
Identities = 34/94 (36%), Positives = 49/94 (51%), Gaps = 1/94 (1%)
Query: 488 EAITPEEKSLFYKIFETYDVEKTGNLDSATAVEIFRKSGLNRSDLEHIWNLCDTNNSGNL 547
E + ++K + +IF T G + A A + KS L + L IW L D + G L
Sbjct: 438 EWVVGKDKPTYDEIFYTLS-PVNGKITGANAKKEMVKSKLPNTVLGKIWKLADVDKDGLL 496
Query: 548 NKQEFALGMHLVYRRLNGEVLPNTLPPSLIPSST 581
+ +EFAL HL+ +L G LP LPP L+P S+
Sbjct: 497 DDEEFALANHLIKVKLEGHELPADLPPHLVPPSS 530
Score = 54.3 bits (129), Expect = 1e-06
Identities = 29/86 (33%), Positives = 52/86 (59%), Gaps = 1/86 (1%)
Query: 192 LSFITTQDQAKFEKLFRSVVTPGSNTITGDQCRNILVKSGLQPHQLAKIWTLSDTNKAGV 251
+ ++ +D+ ++++F ++ +P + ITG + +VKS L L KIW L+D +K G+
Sbjct: 437 VEWVVGKDKPTYDEIFYTL-SPVNGKITGANAKKEMVKSKLPNTVLGKIWKLADVDKDGL 495
Query: 252 LLFPEFALAMYLVNSVLQGDSIPYEL 277
L EFALA +L+ L+G +P +L
Sbjct: 496 LDDEEFALANHLIKVKLEGHELPADL 521
>Hs7657056 [TU] KOG1954 Endocytosis/signaling protein EHD1
Length = 535
Score = 57.4 bits (137), Expect = 1e-07
Identities = 34/95 (35%), Positives = 48/95 (49%), Gaps = 1/95 (1%)
Query: 488 EAITPEEKSLFYKIFETYDVEKTGNLDSATAVEIFRKSGLNRSDLEHIWNLCDTNNSGNL 547
E + +K ++ +IF T G + A A + +S L S L IW L D + G L
Sbjct: 438 EWVVARDKPMYDEIFYTLS-PVDGKITGANAKKEMVRSKLPNSVLGKIWKLADIDKDGML 496
Query: 548 NKQEFALGMHLVYRRLNGEVLPNTLPPSLIPSSTK 582
+ EFAL HL+ +L G LPN LP L+P S +
Sbjct: 497 DDDEFALANHLIKVKLEGHELPNELPAHLLPPSKR 531
Score = 54.3 bits (129), Expect = 1e-06
Identities = 29/84 (34%), Positives = 50/84 (59%), Gaps = 1/84 (1%)
Query: 194 FITTQDQAKFEKLFRSVVTPGSNTITGDQCRNILVKSGLQPHQLAKIWTLSDTNKAGVLL 253
++ +D+ ++++F ++ +P ITG + +V+S L L KIW L+D +K G+L
Sbjct: 439 WVVARDKPMYDEIFYTL-SPVDGKITGANAKKEMVRSKLPNSVLGKIWKLADIDKDGMLD 497
Query: 254 FPEFALAMYLVNSVLQGDSIPYEL 277
EFALA +L+ L+G +P EL
Sbjct: 498 DDEFALANHLIKVKLEGHELPNEL 521
>7299673 [TU] KOG1954 Endocytosis/signaling protein EHD1
Length = 493
Score = 57.0 bits (136), Expect = 2e-07
Identities = 30/72 (41%), Positives = 39/72 (53%)
Query: 511 GNLDSATAVEIFRKSGLNRSDLEHIWNLCDTNNSGNLNKQEFALGMHLVYRRLNGEVLPN 570
G + ATA + KS L S L IW L D + G L+ EFAL +HL+ +L G LP
Sbjct: 420 GKISGATAKQELIKSKLPNSVLSKIWKLSDVDGDGFLDSDEFALALHLINVKLEGCELPT 479
Query: 571 TLPPSLIPSSTK 582
LP L+P S +
Sbjct: 480 VLPEHLVPPSKR 491
>HsM7657054 [TU] KOG1954 Endocytosis/signaling protein EHD1
Length = 543
Score = 56.2 bits (134), Expect = 3e-07
Identities = 27/87 (31%), Positives = 53/87 (60%), Gaps = 1/87 (1%)
Query: 194 FITTQDQAKFEKLFRSVVTPGSNTITGDQCRNILVKSGLQPHQLAKIWTLSDTNKAGVLL 253
++ T+D++K++++F ++ P ++G + + +V + L L +IW LSD ++ G+L
Sbjct: 444 WVVTKDKSKYDEIFYNLA-PADGKLSGSKAKTWMVGTKLPNSVLGRIWKLSDVDRDGMLD 502
Query: 254 FPEFALAMYLVNSVLQGDSIPYELDSR 280
EFALA +L+ + L+G +P L R
Sbjct: 503 DEEFALASHLIEAKLEGHGLPANLPRR 529
Score = 52.0 bits (123), Expect = 6e-06
Identities = 32/95 (33%), Positives = 46/95 (47%), Gaps = 1/95 (1%)
Query: 488 EAITPEEKSLFYKIFETYDVEKTGNLDSATAVEIFRKSGLNRSDLEHIWNLCDTNNSGNL 547
E + ++KS + +IF G L + A + L S L IW L D + G L
Sbjct: 443 EWVVTKDKSKYDEIFYNL-APADGKLSGSKAKTWMVGTKLPNSVLGRIWKLSDVDRDGML 501
Query: 548 NKQEFALGMHLVYRRLNGEVLPNTLPPSLIPSSTK 582
+ +EFAL HL+ +L G LP LP L+P S +
Sbjct: 502 DDEEFALASHLIEAKLEGHGLPANLPRRLVPPSKR 536
>Hs21361462 [TU] KOG1954 Endocytosis/signaling protein EHD1
Length = 543
Score = 56.2 bits (134), Expect = 3e-07
Identities = 27/87 (31%), Positives = 53/87 (60%), Gaps = 1/87 (1%)
Query: 194 FITTQDQAKFEKLFRSVVTPGSNTITGDQCRNILVKSGLQPHQLAKIWTLSDTNKAGVLL 253
++ T+D++K++++F ++ P ++G + + +V + L L +IW LSD ++ G+L
Sbjct: 444 WVVTKDKSKYDEIFYNLA-PADGKLSGSKAKTWMVGTKLPNSVLGRIWKLSDVDRDGMLD 502
Query: 254 FPEFALAMYLVNSVLQGDSIPYELDSR 280
EFALA +L+ + L+G +P L R
Sbjct: 503 DEEFALASHLIEAKLEGHGLPANLPRR 529
Score = 52.0 bits (123), Expect = 6e-06
Identities = 32/95 (33%), Positives = 46/95 (47%), Gaps = 1/95 (1%)
Query: 488 EAITPEEKSLFYKIFETYDVEKTGNLDSATAVEIFRKSGLNRSDLEHIWNLCDTNNSGNL 547
E + ++KS + +IF G L + A + L S L IW L D + G L
Sbjct: 443 EWVVTKDKSKYDEIFYNL-APADGKLSGSKAKTWMVGTKLPNSVLGRIWKLSDVDRDGML 501
Query: 548 NKQEFALGMHLVYRRLNGEVLPNTLPPSLIPSSTK 582
+ +EFAL HL+ +L G LP LP L+P S +
Sbjct: 502 DDEEFALASHLIEAKLEGHGLPANLPRRLVPPSKR 536
>CE23342 [TU] KOG1029 Endocytic adaptor protein intersectin
Length = 1097
Score = 55.5 bits (132), Expect = 6e-07
Identities = 49/197 (24%), Positives = 82/197 (40%), Gaps = 18/197 (9%)
Query: 489 AITPEEKSLFYKIFETYDVEKTGNLDSATAVEIFRKSGLNRSDLEHIWNLCDTNNSGNLN 548
AI K + ++F D E+ G+L S SGL + L HIW L D N G L+
Sbjct: 171 AIPHHNKLKYSQLFNALDKERLGSLSSQVGRSALGLSGLPTNVLAHIWFLSDVNKDGKLS 230
Query: 549 KQEFALGMHLVYRRLNGEVLPNTLPPSLIP----SSTKILNTVKDQLKQGVDKNNRQP-- 602
E+A+ +++ +G LP P L+ SS NT +L+ G + + P
Sbjct: 231 VDEYAISQYMIEMFKSGFALPKITPLELVRMCGISSRSANNT--PELEPGAEPPQKSPAP 288
Query: 603 -TKEDGLRFRNNDDELLPSSRNRRKTIDQSXXXXXXXXXXXXXXXXXREKKELLASEKLR 661
T ED + ++N + RR+ +++ +E++E + R
Sbjct: 289 KTFED--KRQDNLSKGQAELERRRRVLEEE-------EQRRRAEVEKKEREEEAKKNRER 339
Query: 662 LENDSQRKQSENADLLR 678
E + Q + A+L R
Sbjct: 340 QEKERQAEVERQAELER 356
>CE28509 [TU] KOG1954 Endocytosis/signaling protein EHD1
Length = 571
Score = 54.7 bits (130), Expect = 1e-06
Identities = 45/158 (28%), Positives = 64/158 (40%), Gaps = 15/158 (9%)
Query: 427 QAPMQTSLATGG--GFLQPQATGYLPPSNFQATAPLQAQKTGFGNNDLYTSANLASKFIA 484
Q P + + A G G P G +A P GFG + + A
Sbjct: 412 QIPKEEAAAPAGSNGSADPTVRGGAFSQTTEAETPF-----GFGRGEGFDKG-------A 459
Query: 485 RKEEAITPEEKSLFYKIFETYDVEKTGNLDSATAVEIFRKSGLNRSDLEHIWNLCDTNNS 544
+ E + E++ FE+ G L A E KS L S L +W L D +
Sbjct: 460 DEAEWVVSRERTTADSTFESLG-PVNGYLSGRAAKEHMVKSKLPNSVLGKVWKLADIDKD 518
Query: 545 GNLNKQEFALGMHLVYRRLNGEVLPNTLPPSLIPSSTK 582
G L+ EFAL +L+ +L G +P+ LP LIP S +
Sbjct: 519 GQLDADEFALANYLINLKLEGHEIPSELPKHLIPPSKR 556
Score = 53.1 bits (126), Expect = 3e-06
Identities = 30/84 (35%), Positives = 48/84 (56%), Gaps = 1/84 (1%)
Query: 194 FITTQDQAKFEKLFRSVVTPGSNTITGDQCRNILVKSGLQPHQLAKIWTLSDTNKAGVLL 253
++ ++++ + F S+ P + ++G + +VKS L L K+W L+D +K G L
Sbjct: 464 WVVSRERTTADSTFESL-GPVNGYLSGRAAKEHMVKSKLPNSVLGKVWKLADIDKDGQLD 522
Query: 254 FPEFALAMYLVNSVLQGDSIPYEL 277
EFALA YL+N L+G IP EL
Sbjct: 523 ADEFALANYLINLKLEGHEIPSEL 546
>CE25148 [TU] KOG1954 Endocytosis/signaling protein EHD1
Length = 589
Score = 54.7 bits (130), Expect = 1e-06
Identities = 45/158 (28%), Positives = 64/158 (40%), Gaps = 15/158 (9%)
Query: 427 QAPMQTSLATGG--GFLQPQATGYLPPSNFQATAPLQAQKTGFGNNDLYTSANLASKFIA 484
Q P + + A G G P G +A P GFG + + A
Sbjct: 430 QIPKEEAAAPAGSNGSADPTVRGGAFSQTTEAETPF-----GFGRGEGFDKG-------A 477
Query: 485 RKEEAITPEEKSLFYKIFETYDVEKTGNLDSATAVEIFRKSGLNRSDLEHIWNLCDTNNS 544
+ E + E++ FE+ G L A E KS L S L +W L D +
Sbjct: 478 DEAEWVVSRERTTADSTFESLG-PVNGYLSGRAAKEHMVKSKLPNSVLGKVWKLADIDKD 536
Query: 545 GNLNKQEFALGMHLVYRRLNGEVLPNTLPPSLIPSSTK 582
G L+ EFAL +L+ +L G +P+ LP LIP S +
Sbjct: 537 GQLDADEFALANYLINLKLEGHEIPSELPKHLIPPSKR 574
Score = 53.1 bits (126), Expect = 3e-06
Identities = 30/84 (35%), Positives = 48/84 (56%), Gaps = 1/84 (1%)
Query: 194 FITTQDQAKFEKLFRSVVTPGSNTITGDQCRNILVKSGLQPHQLAKIWTLSDTNKAGVLL 253
++ ++++ + F S+ P + ++G + +VKS L L K+W L+D +K G L
Sbjct: 482 WVVSRERTTADSTFESL-GPVNGYLSGRAAKEHMVKSKLPNSVLGKVWKLADIDKDGQLD 540
Query: 254 FPEFALAMYLVNSVLQGDSIPYEL 277
EFALA YL+N L+G IP EL
Sbjct: 541 ADEFALANYLINLKLEGHEIPSEL 564
>CE25147 [TU] KOG1954 Endocytosis/signaling protein EHD1
Length = 835
Score = 54.7 bits (130), Expect = 1e-06
Identities = 45/158 (28%), Positives = 64/158 (40%), Gaps = 15/158 (9%)
Query: 427 QAPMQTSLATGG--GFLQPQATGYLPPSNFQATAPLQAQKTGFGNNDLYTSANLASKFIA 484
Q P + + A G G P G +A P GFG + + A
Sbjct: 676 QIPKEEAAAPAGSNGSADPTVRGGAFSQTTEAETPF-----GFGRGEGFDKG-------A 723
Query: 485 RKEEAITPEEKSLFYKIFETYDVEKTGNLDSATAVEIFRKSGLNRSDLEHIWNLCDTNNS 544
+ E + E++ FE+ G L A E KS L S L +W L D +
Sbjct: 724 DEAEWVVSRERTTADSTFESLG-PVNGYLSGRAAKEHMVKSKLPNSVLGKVWKLADIDKD 782
Query: 545 GNLNKQEFALGMHLVYRRLNGEVLPNTLPPSLIPSSTK 582
G L+ EFAL +L+ +L G +P+ LP LIP S +
Sbjct: 783 GQLDADEFALANYLINLKLEGHEIPSELPKHLIPPSKR 820
Score = 53.1 bits (126), Expect = 3e-06
Identities = 30/84 (35%), Positives = 48/84 (56%), Gaps = 1/84 (1%)
Query: 194 FITTQDQAKFEKLFRSVVTPGSNTITGDQCRNILVKSGLQPHQLAKIWTLSDTNKAGVLL 253
++ ++++ + F S+ P + ++G + +VKS L L K+W L+D +K G L
Sbjct: 728 WVVSRERTTADSTFESL-GPVNGYLSGRAAKEHMVKSKLPNSVLGKVWKLADIDKDGQLD 786
Query: 254 FPEFALAMYLVNSVLQGDSIPYEL 277
EFALA YL+N L+G IP EL
Sbjct: 787 ADEFALANYLINLKLEGHEIPSEL 810
>CE25146 [TU] KOG1954 Endocytosis/signaling protein EHD1
Length = 786
Score = 54.7 bits (130), Expect = 1e-06
Identities = 45/158 (28%), Positives = 64/158 (40%), Gaps = 15/158 (9%)
Query: 427 QAPMQTSLATGG--GFLQPQATGYLPPSNFQATAPLQAQKTGFGNNDLYTSANLASKFIA 484
Q P + + A G G P G +A P GFG + + A
Sbjct: 627 QIPKEEAAAPAGSNGSADPTVRGGAFSQTTEAETPF-----GFGRGEGFDKG-------A 674
Query: 485 RKEEAITPEEKSLFYKIFETYDVEKTGNLDSATAVEIFRKSGLNRSDLEHIWNLCDTNNS 544
+ E + E++ FE+ G L A E KS L S L +W L D +
Sbjct: 675 DEAEWVVSRERTTADSTFESLG-PVNGYLSGRAAKEHMVKSKLPNSVLGKVWKLADIDKD 733
Query: 545 GNLNKQEFALGMHLVYRRLNGEVLPNTLPPSLIPSSTK 582
G L+ EFAL +L+ +L G +P+ LP LIP S +
Sbjct: 734 GQLDADEFALANYLINLKLEGHEIPSELPKHLIPPSKR 771
Score = 53.1 bits (126), Expect = 3e-06
Identities = 30/84 (35%), Positives = 48/84 (56%), Gaps = 1/84 (1%)
Query: 194 FITTQDQAKFEKLFRSVVTPGSNTITGDQCRNILVKSGLQPHQLAKIWTLSDTNKAGVLL 253
++ ++++ + F S+ P + ++G + +VKS L L K+W L+D +K G L
Sbjct: 679 WVVSRERTTADSTFESL-GPVNGYLSGRAAKEHMVKSKLPNSVLGKVWKLADIDKDGQLD 737
Query: 254 FPEFALAMYLVNSVLQGDSIPYEL 277
EFALA YL+N L+G IP EL
Sbjct: 738 ADEFALANYLINLKLEGHEIPSEL 761
>At1g21630 [TU] KOG0998 Synaptic vesicle protein EHS-1 and related EH domain
proteins
Length = 1181
Score = 54.7 bits (130), Expect = 1e-06
Identities = 27/92 (29%), Positives = 47/92 (50%)
Query: 490 ITPEEKSLFYKIFETYDVEKTGNLDSATAVEIFRKSGLNRSDLEHIWNLCDTNNSGNLNK 549
+TP + + K+F D ++ G + A +F L R L+ +W+L D +N L+
Sbjct: 420 MTPADVQKYTKVFVQVDTDRDGKITGNQARNLFLSWRLPRDALKQVWDLSDQDNDSMLSL 479
Query: 550 QEFALGMHLVYRRLNGEVLPNTLPPSLIPSST 581
+EF + ++L+ R G LP P S+I S +
Sbjct: 480 REFCIAVYLMERYREGRPLPPVFPSSIIHSES 511
Score = 52.4 bits (124), Expect = 5e-06
Identities = 27/80 (33%), Positives = 42/80 (51%)
Query: 195 ITTQDQAKFEKLFRSVVTPGSNTITGDQCRNILVKSGLQPHQLAKIWTLSDTNKAGVLLF 254
+T D K+ K+F V T ITG+Q RN+ + L L ++W LSD + +L
Sbjct: 420 MTPADVQKYTKVFVQVDTDRDGKITGNQARNLFLSWRLPRDALKQVWDLSDQDNDSMLSL 479
Query: 255 PEFALAMYLVNSVLQGDSIP 274
EF +A+YL+ +G +P
Sbjct: 480 REFCIAVYLMERYREGRPLP 499
>CE21667 [U] KOG1955 Ral-GTPase effector RALBP1
Length = 424
Score = 53.5 bits (127), Expect = 2e-06
Identities = 34/102 (33%), Positives = 50/102 (48%), Gaps = 9/102 (8%)
Query: 490 ITPEEKSLFYKIFETYDVEKTGNLDSATA--------VEIFRKSGLNRSDLEHIWNLCDT 541
IT +++ + K F G D A V F++S L+ S L IW+L D
Sbjct: 46 ITEKQQEYYTKCFRHLIKTTQGAADLCGALCGADQRIVAFFKRSSLDMSSLSKIWSLADV 105
Query: 542 NNSGNLNKQEFALGMHLVYRRLNGEV-LPNTLPPSLIPSSTK 582
N G L+ EF++ MHLV ++ GEV +P+ LP P T+
Sbjct: 106 NEDGWLDLNEFSIAMHLVVLKVKGEVPIPDVLPGFARPPLTE 147
Database: KOG eukaryal database 04/03
Posted date: Apr 14, 2003 1:07 PM
Number of letters in database: 30,389,216
Number of sequences in database: 60,738
Lambda K H
0.309 0.127 0.357
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 62,613,119
Number of Sequences: 60738
Number of extensions: 2626822
Number of successful extensions: 7714
Number of sequences better than 1.0e-05: 30
Number of HSP's better than 0.0 without gapping: 26
Number of HSP's successfully gapped in prelim test: 4
Number of HSP's that attempted gapping in prelim test: 7557
Number of HSP's gapped (non-prelim): 125
length of query: 1324
length of database: 30,389,216
effective HSP length: 118
effective length of query: 1206
effective length of database: 23,222,132
effective search space: 28005891192
effective search space used: 28005891192
T: 11
A: 40
X1: 16 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.7 bits)