ORF STATUS Function Best COG Functional category Pathways and functional systems
r_klactIV3450 good O KOG3207 Posttranslational modification, protein turnover, chaperones Beta-tubulin folding cofactor E
Only best alignment is shown:
BLASTP 2.2.3 [May-13-2002]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= r_klactIV3450 1173701 1172226 -492
(492 letters)
Database: KOG eukaryal database 04/03
60,738 sequences; 30,389,216 total letters
Searching..................................................done
Color Key for Alignment Scores: 
Score E
Sequences producing significant alignments: (bits) Value
YER007w [O] KOG3207 Beta-tubulin folding cofactor E 234 3e-61
CE18021 [O] KOG3207 Beta-tubulin folding cofactor E 110 5e-24
Hs4507375 [O] KOG3207 Beta-tubulin folding cofactor E 101 3e-21
SPAC22H10.10 [O] KOG3207 Beta-tubulin folding cofactor E 82 2e-15
7302192 [O] KOG3207 Beta-tubulin folding cofactor E 77 6e-14
YKL193c [T] KOG0531 Protein phosphatase 1 regulatory subunit and... 73 1e-12
CE12502 [T] KOG0531 Protein phosphatase 1 regulatory subunit and... 62 3e-09
Hs4506013 [T] KOG0531 Protein phosphatase 1 regulatory subunit a... 59 1e-08
CE04278 [R] KOG0619 FOG: Leucine rich repeat 59 2e-08
CE01090 [T] KOG0531 Protein phosphatase 1 regulatory subunit and... 57 5e-08
Hs18597149 [T] KOG0531 Protein phosphatase 1 regulatory subunit ... 56 1e-07
7300250 [T] KOG0531 Protein phosphatase 1 regulatory subunit and... 54 7e-07
CE02457 [T] KOG0531 Protein phosphatase 1 regulatory subunit and... 52 2e-06
At1g71400 [R] KOG0619 FOG: Leucine rich repeat 52 2e-06
At5g19680 [T] KOG0531 Protein phosphatase 1 regulatory subunit a... 52 2e-06
CE29646 [R] KOG0619 FOG: Leucine rich repeat 52 3e-06
CE07632 [R] KOG0619 FOG: Leucine rich repeat 52 3e-06
>YER007w [O] KOG3207 Beta-tubulin folding cofactor E
Length = 518
Score = 234 bits (596), Expect = 3e-61
Identities = 146/505 (28%), Positives = 265/505 (51%), Gaps = 24/505 (4%)
Query: 1 MQINVNDRLNIGGEFCTVRYIGSLPEWPNIVAYGLEWDNKQRGKHDGTLNGVRYFRTSDG 60
M + DRL IGG FCT+++IG + WP++ AYG+EWD+ RGKH GT++ + YF
Sbjct: 1 MTYEIGDRLKIGGYFCTIKFIGVIKPWPSVKAYGVEWDDHSRGKHSGTIDDIHYFDVQI- 59
Query: 61 QSSGSFVKETKLDTSRQERTSFEGALLMKYGDTSSIDITYKFGSKETESYGFEHLNEMNS 120
+SGSF+KE+K+ + R +F AL KYG +S+ G+K E GF+ LN N
Sbjct: 60 PNSGSFLKESKIKSPGVRRITFYEALSEKYGGSSNNINDLSIGNKRVEGLGFDELNARNK 119
Query: 121 DFDKLESITLSENNIFRAFKTTCSSIPFNSAHSSLRYLDLSFNLFSDINEVYRILRLFPS 180
++ KL I L ++++ F+ +++ LDLS NLF++IN + + +
Sbjct: 120 NYKKLRKIALRDSDVAILFQNQDELNRVIQNCVNVKDLDLSLNLFTNINSLCEFIEPLKN 179
Query: 181 VETVILSGNCFTKLEA--DSSEQFEFSNVKELSMACCKLRNGDIETIIEAFPQIKALDIS 238
+E++ +S N KL + D+ ++++ S++K L ++ C L I ++++F +K LD+S
Sbjct: 180 LESLNISQN---KLLSGWDNLKEYDLSHIKTLRLSSCGLSYKHIGKLLKSFRTLKMLDLS 236
Query: 239 SNLLSKL------PDVLTSLQEINISDNLFIGFPKVLSKESSLTSIDISENKISDLNDLN 292
N L+ ++ +L+E+NIS N I FP + K +L +++S N+IS +
Sbjct: 237 YNNLTSAGIQNFENEIPCTLEELNISGNNLISFP-LFPKNLTLKGLNVSNNQISRAPSIA 295
Query: 293 TNSHIMTLRIDRNRITSWEEIDSINTVFPKLETLWIKKNPVCFE------DTQKGFYSII 346
S + +L I N+ ID +N FP L+ + + N + + Q FY ++
Sbjct: 296 IYS-VESLDITDNKFKERSLIDDLNKTFPSLKNIHLSGNEFNYNGNYINVEEQATFYEVL 354
Query: 347 ARLKSLKCVDGTRISEDIRNEAELYFISLVLSSQINYDTQSAMWNHLTLKHSINTESRTT 406
AR + ++G+ R EAE++F+S V++++++YDT W+ L + I+ +
Sbjct: 355 ARFDRVMVLNGSICDVKTRREAEMFFVSKVMNNELSYDTNLPRWSSLIKSYEIDMSKLSF 414
Query: 407 VQQTNFLSKELIEIPIVYDSEP---IKLKLLKSFSVRYLKTFLRYKFNLQ-GEISLQYSV 462
+ +++I I +P + +L SF+VRY+K+ + K N + L +
Sbjct: 415 NNERETRQSLVLKIKIRAGKKPSSDLDYWVLPSFTVRYVKSVICRKLNFDILNVKLFHEN 474
Query: 463 MDNIKHDFTNEFSPLATYNIEESTI 487
+ + ++ F P++ +N+ I
Sbjct: 475 SEGMINEIKYNFRPISDFNVVNGDI 499
>CE18021 [O] KOG3207 Beta-tubulin folding cofactor E
Length = 493
Score = 110 bits (275), Expect = 5e-24
Identities = 103/399 (25%), Positives = 178/399 (43%), Gaps = 27/399 (6%)
Query: 3 INVNDRLNIGGEFCTVRYIGSLPEWPNIVAYGLEWDNKQRGKHDGTLNGVRYFRTSDGQS 62
+ + R+ I E TVRYIG + + + GLEWD+ RGKHDG + G RYF+T +
Sbjct: 1 MEIGQRVRINFEVATVRYIGEVDGYGSQRWVGLEWDDPTRGKHDGIVRGKRYFQTRH-PN 59
Query: 63 SGSFVKETKLDTSRQERTSFEGALLMKYGDTSSI--DITYKFGSKETESYGFEHLNEMNS 120
GS +K + + T + +Y + S+ +I +K+ E G + S
Sbjct: 60 GGSLMKHEIV----PKPTDLLFEIKDRYIEEESVETEIELAQSNKKIELIGMDQTAAKQS 115
Query: 121 DFDKLESITLSENNIFRAFKTTCSSIPFNSAHSSLRYLDLSFNLFSDINEVYRILRLFPS 180
+ +KL +I L ++ F + S F R L+L NL V +IL FP
Sbjct: 116 NIEKLINIVLDNRSV--GFPPSSDSPQF----ILCRELNLYGNLLYKWKTVRQILEYFPR 169
Query: 181 VETVILSGN---CFTKLEADSSEQFE----FSNVKELSMACCKLRNGDIETIIEAFPQIK 233
++ + L N CF + E D + + + K+L ++ C L I++I+ FP
Sbjct: 170 IQELNLRRNRMQCFNEEEDDDESEGDDHVYSDSCKKLVISECNLSENSIDSILLRFPSTS 229
Query: 234 ALDISSNLLSKL---PDVLTSLQEINISDNLFIGFPKVLSKESSLTSIDISENKISDLND 290
+ N L++ V + L +++ DN F + +LT + ++ I+ LN
Sbjct: 230 DVVAFGNDLTRFSVSEAVSSRLTSLDLEDNPFKTLDSIHGTFPNLTQLSVANCGITSLNG 289
Query: 291 LNTN---SHIMTLRIDRNRITSWEEIDSINTVFPKLETLWIKKNPVCFEDTQKGFYSIIA 347
+ + + L I RN I W+ ++SI ++ L+ L + E + +IA
Sbjct: 290 FDGSIKFPKLEYLNIKRNSIVEWKSVNSIRSL-KSLKRLLFDCKKLSTEKGVHAYEIVIA 348
Query: 348 RLKSLKCVDGTRISEDIRNEAELYFISLVLSSQINYDTQ 386
+L +L ++ +SE R AE+ F++ N D Q
Sbjct: 349 KLSTLIDLNRFDVSEVERRSAEIRFLNKYAGLNDNEDHQ 387
>Hs4507375 [O] KOG3207 Beta-tubulin folding cofactor E
Length = 527
Score = 101 bits (251), Expect = 3e-21
Identities = 115/485 (23%), Positives = 212/485 (43%), Gaps = 59/485 (12%)
Query: 5 VNDRLNIGGEFCTVRYIGSLPE----WPNIVAYGLEWDNKQRGKHDGTLNGVRYFRTSDG 60
+ R+ + GE TVR+ G +P W G+EWDN +RGKHDG+ G YF+
Sbjct: 10 IGRRVEVNGEHATVRFAGVVPPVAGPW-----LGVEWDNPERGKHDGSHEGTVYFKCRH- 63
Query: 61 QSSGSFVKETKLDTSRQERTSFEGALLMKYG-DTSSIDITYKFGSKETESYGFEHLNEMN 119
+ GSF++ K++ T+ + +++ G + + G+K E+ GF+ + +
Sbjct: 64 PTGGSFIRPNKVNFGTDFLTAIKNRYVLEDGPEEDRKEQIVTIGNKPVETIGFDSIMKQQ 123
Query: 120 SDFDKLESITLSENNIFRAFKTTCSSIPFNSAHS--SLRYLDLSFNLFSDINEVYRILRL 177
S KL+ ++L R +C+ A + ++R +DLS NL S +EV I
Sbjct: 124 SQLSKLQEVSL------RNCAVSCAGEKGGVAEACPNIRKVDLSKNLLSSWDEVIHIADQ 177
Query: 178 FPSVETVILSGNCFTKLEADSSEQFEFSNVKELSMACCKLRNGDIETIIEAFPQIKALDI 237
+E + +S N K + S S +K L + + ++ + P ++ L +
Sbjct: 178 LRHLEVLNVSENKL-KFPSGSVLTGTLSVLKVLVLNQTGITWAEVLRCVAGCPGLEELYL 236
Query: 238 SSN--LLSKLP-DVLTSLQEINISDNLFIGFPK--VLSKESSLTSIDISENKISDLNDLN 292
SN +S+ P DVL +++ +++S N I + +++ L + +S+ IS L+ +
Sbjct: 237 ESNNIFISERPTDVLQTVKLLDLSSNQLIDENQLYLIAHLPRLEQLILSDTGISSLHFPD 296
Query: 293 TNSHIMT--------LRIDRNRITSWEEIDSINTVFPKLETLWIKKNPVCFED--TQKGF 342
T L ++ N+I+ W + + + P L L +NP+ ED +
Sbjct: 297 AGIGCKTSMFPSLKYLVVNDNQISQWSFFNELEKL-PSLRALSCLRNPLTKEDKEAETAR 355
Query: 343 YSIIARLKSLKCVDGTRISEDIRNEAELYFISLV-----------------LSSQINYDT 385
IIA + LK ++ I + R AEL + LS + + T
Sbjct: 356 LLIIASIGQLKTLNKCEILPEERRRAELDYRKAFGNEWKQAGGHKDPEKNRLSEE--FLT 413
Query: 386 QSAMWNHLTLKHSINTESRTTVQQTNFLSKELIEIPIVY----DSEPIKLKLLKSFSVRY 441
+ L LK+ + QQ L +L+ + I Y D + ++ +L S +++
Sbjct: 414 AHPRYQFLCLKYGAPEDWELKTQQPLMLKNQLLTLKIKYPHQLDQKVLEKQLPGSMTIQK 473
Query: 442 LKTFL 446
+K L
Sbjct: 474 VKGLL 478
>SPAC22H10.10 [O] KOG3207 Beta-tubulin folding cofactor E
Length = 511
Score = 81.6 bits (200), Expect = 2e-15
Identities = 98/436 (22%), Positives = 185/436 (41%), Gaps = 40/436 (9%)
Query: 46 DGTLNGVRYFRTSDGQSSGSFVKETKLDTSR----QERTSFEGALLMKYGDTSSIDITYK 101
D +N ++ +T VKE K+ + +F AL KY +S + + +
Sbjct: 33 DKNVNAKQFVKTCWRNKKPLIVKEGKIFVDKGFPFDPCRTFLEALYEKYSYSSPLPSSVE 92
Query: 102 FGS-KETESYGFEHLNEMNSDFDKLESITLSENNIFRAFKTTCSSIPFNSAHSSLRYLDL 160
F S K+ E GFE + D L I L I + ++ + LDL
Sbjct: 93 FKSGKQVEFCGFEKIQSKQRDLKSLRVIILDNYRI----EDIEIEYEYSKILPEVIDLDL 148
Query: 161 SFNLFSDINEVYRILRLFPSVETVILSGNCFTKLEADSSEQFEFSNVKELSMACCKLRNG 220
S NLF + + ++ PS+ + L N F+ S+ ++ +LS+ C L +
Sbjct: 149 SRNLFHEFFPILKLCSQLPSLRNLTLDSNLFSNF-ISSNTVLLIPHLTQLSVNGCGLNSK 207
Query: 221 DIETIIEAFPQIKALDISSN--LLSKLPDV--LTSLQEINISD--NLFIGFPKVLSKESS 274
D++ I E FP ++ L + +N +LSK L LQ +++++ NL+ +
Sbjct: 208 DVQWITETFPSLEVLYLEANEIILSKATSFKNLQFLQTLSLANNLNLYSADGYAVDVFQG 267
Query: 275 LTSIDISENKISDLNDLNTNS-HIMT-LRIDRNRITSWEEIDSINTVFPKLETLWIKKNP 332
+ ++++S ++D+ +L ++ H +T L I N I +D + T LE L +
Sbjct: 268 INNLNLSSTSLADVAELPVHTLHKLTFLDISENNIRDIRSLDHLRT----LENLKHLRIT 323
Query: 333 VCF--EDTQKGFYSIIARLKSLKCVDGTRISEDIRNEAELYFISLVLSSQINYDTQSA-- 388
+ + + T +IAR+ SL ++ IS + R +AELY+ S + I+ + +
Sbjct: 324 LSYFNKPTDIAKLLVIARIPSLVKLNDVNISPNERLDAELYYTSCIRKLVIDNEIKDVEE 383
Query: 389 ------MWNHLTLKHSI-----NTESRTTVQQTNFLSKEL---IEIPIVYDSEPIKLKLL 434
W + H + + E+ + L + I+I + + LKL
Sbjct: 384 LTKIEPFWEEIWKSHELPSIQFHLEASINDWTSGILKNRITKGIKISSINSGATMLLKLH 443
Query: 435 KSFSVRYLKTFLRYKF 450
++ + +K + Y F
Sbjct: 444 YNWKLLDIKALISYHF 459
>7302192 [O] KOG3207 Beta-tubulin folding cofactor E
Length = 444
Score = 77.0 bits (188), Expect = 6e-14
Identities = 93/413 (22%), Positives = 175/413 (41%), Gaps = 73/413 (17%)
Query: 8 RLNIGGEFCTVRYIGSLP----EWPNIVAYGLEWDNKQRGKHDGTLNGVRYFRTSDGQSS 63
R+ IG + TVRY+G + W G+EWD+ RGKH+G ++G RYF+T +
Sbjct: 17 RIKIGDNYGTVRYVGEVSGHMGSW-----LGIEWDDGLRGKHNGIVDGKRYFQTQT-PTG 70
Query: 64 GSFVKETKL-------DTSRQERTSFEGALLMKYGDTSSI-DITYKFGSKETESYGFEHL 115
GSF++ K+ D +R+ +++ + + D S I + + E G + +
Sbjct: 71 GSFIRPGKVGPCATLEDAARERYLNYDSSNV----DESLIREAQASLQASLFEVVGMDKI 126
Query: 116 NEMNSDFDKLESITLSENNIFRAFKTTCSSIPFNSAHSSLRYLDLSFNLFSDINEVYRIL 175
S F++LE +++ + T ++ + + L L++S L + V I
Sbjct: 127 ARKQSKFEQLEEVSVDQ--------TPVNAAGYLKELTHLTTLNVSHTLIWNWEIVASIA 178
Query: 176 RLFPSVETVILSGNCFTKLEADSSEQFE--FSNVKELSMACCKLRN-GDIETIIEAFPQI 232
+ PS+ + LS N + + E F +K +++ C + D+ +P I
Sbjct: 179 QQLPSLTNLNLSSNRLVLPTSSQITELEPSFRQLKRINLRSCGFSDWKDVMHTALLWPNI 238
Query: 233 KALDISSNLLSKLPDV-----LTSLQEINISDNLFIGFPKV--LSKESSLTSIDISENKI 285
+L + N L +L +V L E+++ + F +V L ++L ++I EN I
Sbjct: 239 LSLGLQENSLGQLAEVDRTKIFKQLHELDLHRTNIMDFDQVTKLGNLTTLRLLNIMENGI 298
Query: 286 SDL--------NDLNTNSHIMTLRIDRNRITSWEEI-------------------DSINT 318
++ LN + L + N I W E+ D+ N
Sbjct: 299 EEIKLPDCDSQEKLNIFVSLEQLNLLHNPI--WNEVGQRFFGTKKFTVIMLSSQADAFNE 356
Query: 319 V--FPKLETLWIKKNPVCFEDTQKGFYSIIARLKSLKCVDGTRISEDIRNEAE 369
+ P+L+ L K P + + F +A + SL+ ++ ++ + R AE
Sbjct: 357 LDKLPQLKRL--SKTPHLKSNFDEMFSKAVASIASLQFINKAEVTAEQRRGAE 407
>YKL193c [T] KOG0531 Protein phosphatase 1 regulatory subunit and related
proteins
Length = 338
Score = 72.8 bits (177), Expect = 1e-12
Identities = 82/319 (25%), Positives = 150/319 (46%), Gaps = 24/319 (7%)
Query: 55 FRTSDGQSSGSFVKETK-LDTSRQERTSFEGALLMKYGDTSSIDITYKFGSKETESYGFE 113
F T+D + + + + +D + S E L ++ + + + +E
Sbjct: 29 FITADSELTQDLPDDVEVIDLVHLKIKSLEDLNLYRFKNLKQLCLRQNLIESISEVEVLP 88
Query: 114 HLNEMNSDF--DKLESITLSENNIFRAFKTTCSSIPFNSAH--SSLRYLDLSFNLFSDIN 169
H ++ DF +K++ I+ +N+ + K T + FN +L L NL+ N
Sbjct: 89 HDKIVDLDFYDNKIKHIS---SNVNKLTKLTSLDLSFNKIKHIKNLENLTDLENLYFVQN 145
Query: 170 EVYRI--LRLFPSVETVILSGNCFTKLEADSSEQFEFSNVKELSMACCKLRNGDIETIIE 227
+ +I L S++ + L GN +E DS E SN++E+ + I +I
Sbjct: 146 SISKIENLSTLKSLKNLELGGNKVHSIEPDSFEGL--SNLEEIWLG-----KNSIPRLIN 198
Query: 228 AFP--QIKALDISSNLLSKLPDV--LTSLQEINISDNLFIGFPKVLSKESSLTSIDISEN 283
P +K L I SN L K+ ++ LT+L+E+ +S N FI + L K LT++D++ N
Sbjct: 199 LHPLKNLKILSIQSNKLKKIENLEELTNLEELYLSHN-FITKIEGLEKNLKLTTLDVTSN 257
Query: 284 KISDLNDLNTNSHIMTLRIDRNRI-TSWEEIDSINTVFPKLETLWIKKNPVCFEDTQKGF 342
KI+ L +LN S++ + N+I S+E + + +LET++++ NP+ E+
Sbjct: 258 KITSLENLNHLSNLTDIWASFNKIDQSFESLGENLSALSRLETIYLEGNPIQLENKTSYR 317
Query: 343 YSIIARL-KSLKCVDGTRI 360
+ L SL+ +D T I
Sbjct: 318 RKLTMNLPPSLQKIDATYI 336
>CE12502 [T] KOG0531 Protein phosphatase 1 regulatory subunit and related
proteins
Length = 630
Score = 61.6 bits (148), Expect = 3e-09
Identities = 61/233 (26%), Positives = 110/233 (47%), Gaps = 27/233 (11%)
Query: 148 FNSAHSSLRYLDLSFNLFSDINEVYRILRLFPSVETVILSGNCFTKLEADSSEQFEFSNV 207
F + +S +++L +S N F + + ++LFP + + K AD F + N+
Sbjct: 72 FAAEYSEVKHLKISGNCF----QKFTYIKLFPKCQIIDARDCQINKFIAD----FNY-NL 122
Query: 208 KELSMACCKLRNGDIETIIEAFPQIKALDISSNLLSKLPDV---LTSLQEINISDNLFIG 264
EL +A +L+ + + F +K LD+S+NL+ P V L +L+ +N+S N
Sbjct: 123 LELHLARNQLKETNQ---LGRFENLKILDLSNNLIE--PPVSFSLKNLEILNLSGNFLNE 177
Query: 265 FPKVLSKESSLTSIDISENKISDLNDLN---TNSHIMTLRIDRNRITSWEEIDSINTVFP 321
P LSK +L +I +++NKISDL + +++ L I N I + ++T F
Sbjct: 178 IPD-LSKCVALQTISLADNKISDLTTITKLICPTNLKNLDISSNSIEDLSQFSVLST-FK 235
Query: 322 KLETLWIKKNPVCFEDTQKGFYSIIARL-----KSLKCVDGTRISEDIRNEAE 369
KLE + NP + + + + L +DG +I + ++ E E
Sbjct: 236 KLEEFVVAGNPSITSVLDSDLFDYRSYIFACCSEQLHTIDGQKIEDQVQTEGE 288
>Hs4506013 [T] KOG0531 Protein phosphatase 1 regulatory subunit and related
proteins
Length = 360
Score = 59.3 bits (142), Expect = 1e-08
Identities = 63/271 (23%), Positives = 123/271 (45%), Gaps = 53/271 (19%)
Query: 113 EHLNEMNSDFDKLESITLSENNIFRAFKTTCSSIPFNSAHSSLRYLDLSFNLFSDINEVY 172
E+L E+ S L + L +N I I A + L LD+SFNL +I V
Sbjct: 114 ENLEELQS----LRELDLYDNQI--------KKIENLEALTELEILDISFNLLRNIEGVD 161
Query: 173 RILRLFPSVETVILSGNCFTKLEADSSEQFEFSNVKELSMACCKLRNGDIETI--IEAFP 230
++ RL + + L N +K+E SN+ +L M +L + I I I+
Sbjct: 162 KLTRL----KKLFLVNNKISKIE-------NLSNLHQLQML--ELGSNRIRAIENIDTLT 208
Query: 231 QIKALDISSNLLSKLP--DVLTSLQEINISDN----------------LFIGFPKV---- 268
+++L + N ++KL D LT+L +++ N L++ +
Sbjct: 209 NLESLFLGKNKITKLQNLDALTNLTVLSMQSNRLTKIEGLQNLVNLRELYLSHNGIEVIE 268
Query: 269 -LSKESSLTSIDISENKISDLNDLNTNSHIMTLRIDRNRITSWEEIDSINTVFPKLETLW 327
L + LT +DI+ N+I + +++ + + ++ N + SW ++D + LET++
Sbjct: 269 GLENNNKLTMLDIASNRIKKIENISHLTELQEFWMNDNLLESWSDLDELKGA-RSLETVY 327
Query: 328 IKKNPVCFEDTQKGFYSIIARLKSLKCVDGT 358
+++NP+ + + ++ L S++ +D T
Sbjct: 328 LERNPLQKDPQYR--RKVMLALPSVRQIDAT 356
>CE04278 [R] KOG0619 FOG: Leucine rich repeat
Length = 1066
Score = 58.9 bits (141), Expect = 2e-08
Identities = 50/173 (28%), Positives = 91/173 (51%), Gaps = 14/173 (8%)
Query: 120 SDFDKLESITLSENNIFRAFKTTCSSIPFNSAHSSLRYLDLSFNLFSDINEVYRILRLFP 179
SD D L+ + LS NNI T +S+ F++ + LRYLDLS N I + L P
Sbjct: 461 SDLDNLQQLRLSHNNI-----RTITSMTFSNLRN-LRYLDLSHNRIIKI--LPSALYQLP 512
Query: 180 SVETVILSGNCFTKLEADSSEQFEFSNVKELSMACCKLRNGDIETIIEAFPQIKALDISS 239
+++ + L N +++ D+ F S+++ L ++ R E + + Q+ LD+SS
Sbjct: 513 ALDVLHLDHNNLNEIDRDAFRSF--SDLQSLKLSHNAFRRFSCE-FLGSISQVHQLDLSS 569
Query: 240 NLLSKLPD--VLTSLQEINISDNLFIGFP-KVLSKESSLTSIDISENKISDLN 289
N ++++ + +++++++ N K+L + LTSIDIS N I D++
Sbjct: 570 NQINEIDIFCIARGIRKLSLASNSVEKINRKLLQDATELTSIDISHNGIIDVD 622
>CE01090 [T] KOG0531 Protein phosphatase 1 regulatory subunit and related
proteins
Length = 326
Score = 57.4 bits (137), Expect = 5e-08
Identities = 63/300 (21%), Positives = 135/300 (45%), Gaps = 38/300 (12%)
Query: 92 DTSSIDITYKFGSKETESYGFEHLNEMNSDFDKLESITLSENNIFRA-----FKTTCSSI 146
D+ ID+T+ + GF + E+ + L SI+ + +++ ++ + I
Sbjct: 37 DSPEIDLTHTRADHIPDLTGFPKIEELRMRNNLLVSISPTISSLVTLTSLDLYENQLTEI 96
Query: 147 PFNSAHSSLRYLDLSFNLFSDINEVYRILRLFPSVETVILSGNCFTKLE-ADSSEQFEFS 205
+ +L LDLS+N IN + ++ +L ET+ L N K+E ++ Q +
Sbjct: 97 SHLESLVNLVSLDLSYNRIRQINGLDKLTKL----ETLYLVSNKIEKIENLEALTQLKLL 152
Query: 206 -----------------NVKELSMACCKLRNGDIETIIEAFPQIKALDISSNLLSKLPDV 248
N+ EL + K+R + +E ++ L + N + K+ +V
Sbjct: 153 ELGDNRIKKIENIGHLVNLDELFIGKNKIRQLEG---VETLQKLSVLSLPGNRIVKIENV 209
Query: 249 --LTSLQEINISDNLFIGFPKVLSKE--SSLTSIDISENKISDLNDLNTNSHIMTLRIDR 304
L +L+E+ +SD G + E ++L +D++ N+I + + + +
Sbjct: 210 EQLNNLKELYLSDQ---GLQDIHGVEPLTNLLLLDVANNEIKTFSGVERLESLNDFWAND 266
Query: 305 NRITSWEEIDSINTVFPKLETLWIKKNPVCFEDTQKGFYSIIARLKSLKCVDGTRISEDI 364
N++ S+ EI+ ++ + L+T+++++NP F DT + ++ L + +D T + I
Sbjct: 267 NKVESFSEIEQLSKL-KGLQTVYLERNPFYFNDTNQYRRKVMMTLTQVTQIDATTCRKPI 325
>Hs18597149 [T] KOG0531 Protein phosphatase 1 regulatory subunit and related
proteins
Length = 987
Score = 55.8 bits (133), Expect = 1e-07
Identities = 54/228 (23%), Positives = 106/228 (45%), Gaps = 21/228 (9%)
Query: 173 RILRLFPSVETVI----------LSGNCFTKLEA---DSSEQFEFSNVKEL-SMACCKLR 218
RIL ++PS + + LSGNC+ K+ A D FE +N+++L ++
Sbjct: 646 RILSIWPSAKILTQVSKLGPHLHLSGNCYLKITALNLDGQHLFEITNLEKLENLKWASFS 705
Query: 219 NGDIETI--IEAFPQIKALDISSNLLSKLPDV--LTSLQEINISDNLFIGFPK-VLSKES 273
N ++ + +E+ ++ L + N +SK+ + +T L ++I++NL G+ +
Sbjct: 706 NNNLTKMEGLESCINLEELTLDGNCISKIEGISKMTKLTRLSINNNLLTGWEEHTFDNML 765
Query: 274 SLTSIDISENKISDLNDLNTNSHIMTLRIDRNRITSWEEIDSINTVFPKLETLWIKKNPV 333
L S+ + N+I+ L+ L + ++ L I N I +E+ ++ + L L + N +
Sbjct: 766 HLHSLSLENNRITSLSGLQKSFTLVELYISNNYIAVNQEMHNLKGLC-NLVILDMCGNII 824
Query: 334 CFEDTQKGFYSIIARLKSLKCVDGTRISEDIRNEAELYFISLVLSSQI 381
+ + +I L LK +DG I + A+ F + S I
Sbjct: 825 IWNQENYRLF-VIFHLPELKALDGIPIEPSETDSAKDLFGGRLTSDMI 871
>7300250 [T] KOG0531 Protein phosphatase 1 regulatory subunit and related
proteins
Length = 326
Score = 53.5 bits (127), Expect = 7e-07
Identities = 46/181 (25%), Positives = 88/181 (48%), Gaps = 18/181 (9%)
Query: 155 LRYLDLSFNLFSDINEVYRILRLFPSVETVILSGNCFTKLEADSSEQFEFSNVKELSMAC 214
L LD+SFN + I + ++++L E V N T++E +N+ L +
Sbjct: 107 LEVLDISFNRLTKIENLDKLVKL----EKVYFVSNRITQIENLDM----LTNLTMLELGD 158
Query: 215 CKLRNGDIETIIEAFPQIKALDISSNLLSKLP--DVLTSLQEINISDNLFIGFPKVLSKE 272
KL+ IE I E ++ L + N ++K+ D L +L+ +++ N + L K
Sbjct: 159 NKLKK--IENI-EMLVNLRQLFLGKNKIAKIENLDTLVNLEILSLQANRIVKIEN-LEKL 214
Query: 273 SSLTSIDISENKISDLNDLNTNSHIMTLRIDRNRITSWEEIDSINTVFPKLETLWIKKNP 332
++L + +SEN + + +L+ N+ + TL + +NR+ ++ + LE LW+ N
Sbjct: 215 ANLRELYVSENGVETIENLSENTKLETLDLAKNRLKGIANLEKLEL----LEELWLNHNG 270
Query: 333 V 333
V
Sbjct: 271 V 271
>CE02457 [T] KOG0531 Protein phosphatase 1 regulatory subunit and related
proteins
Length = 349
Score = 52.4 bits (124), Expect = 2e-06
Identities = 63/309 (20%), Positives = 142/309 (45%), Gaps = 39/309 (12%)
Query: 92 DTSSIDITYKFGSKETESYGF----EHLNEMNSDFDKLESIT-LSENNIFRAFKTTCSSI 146
D ++D+T + KE Y + EH + + K+E++ L+ + + +
Sbjct: 33 DAKNVDLT-RHRIKEIGDYSWLTHVEHFSFRWNLIKKIENLDCLTTLTHLEFYDNQITKV 91
Query: 147 PFNSAHSSLRYLDLSFNLFSDINEVYRILRLFPSVETVILSGNCFTKLEA-DSSEQFEFS 205
+ +L LDLSFN + I + ++ +L +T+ N TK+E D+ + E+
Sbjct: 92 ENLDSLVNLESLDLSFNRITKIENLEKLTKL----KTLFFVHNKITKIEGLDTLTELEYL 147
Query: 206 NVKELSMACCKLRNGDIET-----------IIEAFPQIKALDISS---NLLSKLPDV--L 249
+ + +A + + +++ +IE +K L + S N ++ + ++ L
Sbjct: 148 ELGDNRIAKIENLDNNLKLDRLFLGANQIRLIENVDHLKKLTVLSLPANAITVVDNISGL 207
Query: 250 TSLQEINISDNLFIGFPKVLSKESSLTSIDISENKISDLNDLNTNSHIMTLRIDRNRITS 309
+L+EI ++ N I + + + L +D ++N++ + +++ + N++ +
Sbjct: 208 HNLKEIYLAQN-GIKYVCGIDEHLPLEILDFNQNRLEKVENIHQLKTLTDFWARGNKLDN 266
Query: 310 WEEIDSINTVFPKLETLWIKKNPVCFEDTQKGFYSIIARLKSLKCVDGTRISE------- 362
W +D + P+L ++++ NP+ DT +G +I L+ + +DGT+ E
Sbjct: 267 WSIMDEL-VELPQLNSVYLDFNPIASVDTYRG--KVIHLLQQITRLDGTQCREHSMLRPP 323
Query: 363 -DIRNEAEL 370
+ +NE EL
Sbjct: 324 KEEKNETEL 332
>At1g71400 [R] KOG0619 FOG: Leucine rich repeat
Length = 846
Score = 52.4 bits (124), Expect = 2e-06
Identities = 74/293 (25%), Positives = 119/293 (40%), Gaps = 57/293 (19%)
Query: 50 NGVRYFRTSDGQSSGSFVKETKLDTSRQ----ERTSFEGALLMKYGDTSSIDITYKFGSK 105
+ + YF S SG F K L S + + F G + ++ +TSS
Sbjct: 301 HNLEYFDVSYNSFSGPFPKSLLLIPSLESIYLQENQFTGPI--EFANTSSSTKLQDLILG 358
Query: 106 ETESYGFEHLNEMNSDFDKLESITLSENNIFRAFKTTCSSIPFNSAHSSLRYLDLSFNLF 165
+G + E S LE + +S NN A T S + +L +LDLS N
Sbjct: 359 RNRLHG--PIPESISRLLNLEELDISHNNFTGAIPPTISKLV------NLLHLDLSKN-- 408
Query: 166 SDINEVYRILRLFPSVETVILSGNCFTKLEADSSEQFEFSNVKELSMACCKLRNGDIETI 225
N + + T++LS N F+ E S E+ + ++EL + + G I +
Sbjct: 409 ---NLEGEVPACLWRLNTMVLSHNSFSSFENTSQEE---ALIEELDLNSNSFQ-GPIPYM 461
Query: 226 IEAFPQIKALDISSNLLS-KLPDVLT----SLQEINISDNLFIG-FPKVLSKESSLTSID 279
I + LD+S+NL S +P + S++E+N+ DN F G P + SK + L S+D
Sbjct: 462 ICKLSSLGFLDLSNNLFSGSIPSCIRNFSGSIKELNLGDNNFSGTLPDIFSKATELVSLD 521
Query: 280 ISEN------------------------KISDLNDLNTNS----HIMTLRIDR 304
+S N KI D+ S H++ LR ++
Sbjct: 522 VSHNQLEGKFPKSLINCKALELVNVESNKIKDIFPSWLESLPSLHVLNLRSNK 574
>At5g19680 [T] KOG0531 Protein phosphatase 1 regulatory subunit and related
proteins
Length = 328
Score = 52.0 bits (123), Expect = 2e-06
Identities = 45/191 (23%), Positives = 90/191 (46%), Gaps = 15/191 (7%)
Query: 147 PFNSAHSSLRYLDLSFNLFSDINEVYRILRLFPSVETVILSGNCFTKLEADSSEQFEFSN 206
P S LDL+ ++ V L P++ + L+ N + L+ S + S
Sbjct: 9 PLEEIGDSNNVLDLTSYQLHSLDTV----ELPPNLIELDLTANRLSGLD---SRIAQLST 61
Query: 207 VKELSMACCKLRNGDIETII--EAFPQIKALDISSNLLSKLPDV--LTSLQEINISDNLF 262
+K+LS+ + + +E + +A ++ L + N L+K+PDV T L +IS N
Sbjct: 62 LKKLSLRQNLIDDSAVEPLSHWDALSDLEELVLRDNKLAKVPDVSIFTKLLVYDISFNEI 121
Query: 263 IGFPKVLSKESSLTSIDISENKISDLNDLNTNSHIMTLRIDRNRITSWEEIDSINTVFPK 322
+ S+L + +S+N+++ + ++ ++ L + NR+ E +++ F K
Sbjct: 122 TSLEGISKASSTLKELYVSKNEVNKIMEIEHLHNLQILELGSNRLRVMENLEN----FTK 177
Query: 323 LETLWIKKNPV 333
LE LW+ +N +
Sbjct: 178 LEELWLGRNRI 188
>CE29646 [R] KOG0619 FOG: Leucine rich repeat
Length = 439
Score = 51.6 bits (122), Expect = 3e-06
Identities = 44/163 (26%), Positives = 82/163 (49%), Gaps = 15/163 (9%)
Query: 203 EFSNVKELSMACCKLRNGDIETIIEAFPQIKALDI---SSNLLSKLPDVL---TSLQEIN 256
+FS +K+L +A N +E + + +K L+I + N L LPD + T L+ I+
Sbjct: 260 QFSQLKQLHLA-----NNCLEFLPDELGSMKKLEILNLAGNKLKALPDTIVGCTDLKTID 314
Query: 257 ISDNLFIGFPKVLSKESSLTSIDISENKISDLNDLNTNSHIMTLRIDRNRITSWEEIDSI 316
+S N+F FP + L ++++ N+I L D +N ++ L +++NR++S +
Sbjct: 315 LSSNVFTVFPVAVIGCLQLDILNLNGNQIESLPDDISNLKVIELSLNQNRLSSLNPSNLA 374
Query: 317 NTVFPKLETLWIKKNPVCFEDTQKGFYSIIARLKSLKCVDGTR 359
T +L TL + +N C E ++ + + S+ DG R
Sbjct: 375 KTT--RLRTLRLDEN--CLEKSEFTRDLLESSTISVMSYDGNR 413
>CE07632 [R] KOG0619 FOG: Leucine rich repeat
Length = 227
Score = 51.6 bits (122), Expect = 3e-06
Identities = 44/163 (26%), Positives = 82/163 (49%), Gaps = 15/163 (9%)
Query: 203 EFSNVKELSMACCKLRNGDIETIIEAFPQIKALDI---SSNLLSKLPDVL---TSLQEIN 256
+FS +K+L +A N +E + + +K L+I + N L LPD + T L+ I+
Sbjct: 48 QFSQLKQLHLA-----NNCLEFLPDELGSMKKLEILNLAGNKLKALPDTIVGCTDLKTID 102
Query: 257 ISDNLFIGFPKVLSKESSLTSIDISENKISDLNDLNTNSHIMTLRIDRNRITSWEEIDSI 316
+S N+F FP + L ++++ N+I L D +N ++ L +++NR++S +
Sbjct: 103 LSSNVFTVFPVAVIGCLQLDILNLNGNQIESLPDDISNLKVIELSLNQNRLSSLNPSNLA 162
Query: 317 NTVFPKLETLWIKKNPVCFEDTQKGFYSIIARLKSLKCVDGTR 359
T +L TL + +N C E ++ + + S+ DG R
Sbjct: 163 KTT--RLRTLRLDEN--CLEKSEFTRDLLESSTISVMSYDGNR 201
Database: KOG eukaryal database 04/03
Posted date: Apr 14, 2003 1:07 PM
Number of letters in database: 30,389,216
Number of sequences in database: 60,738
Lambda K H
0.317 0.134 0.377
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 27,767,025
Number of Sequences: 60738
Number of extensions: 1156906
Number of successful extensions: 4385
Number of sequences better than 1.0e-05: 17
Number of HSP's better than 0.0 without gapping: 2
Number of HSP's successfully gapped in prelim test: 17
Number of HSP's that attempted gapping in prelim test: 4318
Number of HSP's gapped (non-prelim): 51
length of query: 492
length of database: 30,389,216
effective HSP length: 110
effective length of query: 382
effective length of database: 23,708,036
effective search space: 9056469752
effective search space used: 9056469752
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.6 bits)