ORF STATUS Function Best COG Functional category Pathways and functional systems
r_klactIV3505 check: MH U KOG0566 Intracellular trafficking, secretion, and vesicular transport Inositol-1,4,5-triphosphate 5-phosphatase (synaptojanin), INP51/INP52/INP53 family
Only best alignment is shown:
BLASTP 2.2.3 [May-13-2002]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= r_klactIV3505 1190927 1193749 941
(941 letters)
Database: KOG eukaryal database 04/03
60,738 sequences; 30,389,216 total letters
Searching..................................................done
Color Key for Alignment Scores: 
Score E
Sequences producing significant alignments: (bits) Value
YIL002c [U] KOG0566 Inositol-145-triphosphate 5-phosphatase (syn... 964 0.0
SPBC2G2.02 [U] KOG0566 Inositol-145-triphosphate 5-phosphatase (... 462 e-129
YNL106c [U] KOG0566 Inositol-145-triphosphate 5-phosphatase (syn... 453 e-127
YOR109w [U] KOG0566 Inositol-145-triphosphate 5-phosphatase (syn... 437 e-122
SPBC577.13 [U] KOG0566 Inositol-145-triphosphate 5-phosphatase (... 298 2e-80
CE28239 [U] KOG0566 Inositol-145-triphosphate 5-phosphatase (syn... 250 6e-66
CE29050 [U] KOG0566 Inositol-145-triphosphate 5-phosphatase (syn... 250 8e-66
7291368 [U] KOG0566 Inositol-145-triphosphate 5-phosphatase (syn... 244 6e-64
Hs14747866 [U] KOG0566 Inositol-145-triphosphate 5-phosphatase (... 243 1e-63
Hs4507335 [U] KOG0566 Inositol-145-triphosphate 5-phosphatase (s... 234 5e-61
Hs22045277 [U] KOG0565 Inositol polyphosphate 5-phosphatase and ... 207 6e-53
7290234 [U] KOG0565 Inositol polyphosphate 5-phosphatase and rel... 202 2e-51
Hs13325072 [U] KOG0565 Inositol polyphosphate 5-phosphatase and ... 196 2e-49
Hs13325070 [U] KOG0565 Inositol polyphosphate 5-phosphatase and ... 196 2e-49
At2g01900 [U] KOG0565 Inositol polyphosphate 5-phosphatase and r... 157 6e-38
CE17405 [U] KOG0565 Inositol polyphosphate 5-phosphatase and rel... 153 1e-36
At2g37440 [U] KOG0565 Inositol polyphosphate 5-phosphatase and r... 153 1e-36
7302845 [U] KOG0565 Inositol polyphosphate 5-phosphatase and rel... 152 2e-36
At2g32010 [U] KOG0565 Inositol polyphosphate 5-phosphatase and r... 150 9e-36
At1g05470 [U] KOG0565 Inositol polyphosphate 5-phosphatase and r... 146 2e-34
7293245 [U] KOG0565 Inositol polyphosphate 5-phosphatase and rel... 144 6e-34
SPAC9G1.10c [U] KOG0565 Inositol polyphosphate 5-phosphatase and... 143 1e-33
At5g65090 [U] KOG0565 Inositol polyphosphate 5-phosphatase and r... 140 9e-33
At5g04980 [U] KOG0565 Inositol polyphosphate 5-phosphatase and r... 139 2e-32
At2g43900 [U] KOG0565 Inositol polyphosphate 5-phosphatase and r... 138 5e-32
At3g63240 [U] KOG0565 Inositol polyphosphate 5-phosphatase and r... 135 2e-31
At2g31830 [U] KOG0565 Inositol polyphosphate 5-phosphatase and r... 135 2e-31
At4g18010 [U] KOG0565 Inositol polyphosphate 5-phosphatase and r... 134 7e-31
At1g71710 [U] KOG0565 Inositol polyphosphate 5-phosphatase and r... 131 4e-30
Hs5031799 [U] KOG0565 Inositol polyphosphate 5-phosphatase and r... 131 6e-30
7294594 [U] KOG0565 Inositol polyphosphate 5-phosphatase and rel... 130 1e-29
At1g05630 [U] KOG0565 Inositol polyphosphate 5-phosphatase and r... 129 2e-29
Hs20537935 [U] KOG0565 Inositol polyphosphate 5-phosphatase and ... 129 2e-29
At1g47510 [U] KOG0565 Inositol polyphosphate 5-phosphatase and r... 127 1e-28
Hs4755142_1 [U] KOG0565 Inositol polyphosphate 5-phosphatase and... 124 5e-28
At1g34120 [U] KOG0565 Inositol polyphosphate 5-phosphatase and r... 119 2e-26
Hs18765709 [U] KOG0565 Inositol polyphosphate 5-phosphatase and ... 117 6e-26
Hs9845291 [U] KOG0565 Inositol polyphosphate 5-phosphatase and r... 113 2e-24
Hs18765707 [U] KOG0565 Inositol polyphosphate 5-phosphatase and ... 105 4e-22
Hs22068673 [U] KOG0565 Inositol polyphosphate 5-phosphatase and ... 102 3e-21
CE00123 [U] KOG0565 Inositol polyphosphate 5-phosphatase and rel... 100 2e-20
7300754 [I] KOG1890 Phosphoinositide phosphatase SAC1 100 2e-20
CE28690 [U] KOG0565 Inositol polyphosphate 5-phosphatase and rel... 93 2e-18
YOL065c [U] KOG0565 Inositol polyphosphate 5-phosphatase and rel... 92 4e-18
At1g65580 [U] KOG0565 Inositol polyphosphate 5-phosphatase and r... 89 4e-17
Hs7662414 [I] KOG1890 Phosphoinositide phosphatase SAC1 86 4e-16
SPBC19F5.03 [I] KOG1889 Putative phosphoinositide phosphatase 81 9e-15
Hs7662338 [I] KOG1889 Putative phosphoinositide phosphatase 79 3e-14
7292047 [I] KOG1889 Putative phosphoinositide phosphatase 79 3e-14
YKL212w [I] KOG1889 Putative phosphoinositide phosphatase 74 1e-12
At3g51830 [I] KOG1889 Putative phosphoinositide phosphatase 71 9e-12
ECU10g1370 [U] KOG0565 Inositol polyphosphate 5-phosphatase and ... 70 1e-11
ECU03g1160 [I] KOG1889 Putative phosphoinositide phosphatase 69 3e-11
CE09807 [I] KOG1889 Putative phosphoinositide phosphatase 69 4e-11
ECU08g1420 [U] KOG0566 Inositol-145-triphosphate 5-phosphatase (... 59 4e-08
At5g66020 [I] KOG1889 Putative phosphoinositide phosphatase 59 5e-08
CE20170 [I] KOG1890 Phosphoinositide phosphatase SAC1 58 8e-08
YNL325c [I] KOG1888 Putative phosphoinositide phosphatase 57 1e-07
Hs22066542 [U] KOG0565 Inositol polyphosphate 5-phosphatase and ... 54 1e-06
At1g17340 [I] KOG1888 Putative phosphoinositide phosphatase 53 3e-06
>YIL002c [U] KOG0566 Inositol-145-triphosphate 5-phosphatase (synaptojanin)
INP51/INP52/INP53 family
Length = 946
Score = 964 bits (2491), Expect = 0.0
Identities = 482/949 (50%), Positives = 665/949 (69%), Gaps = 24/949 (2%)
Query: 1 MKVYLRKSPRAIALVSNGYVLIFEKRQN----STSSFLKGGSPKVTVQSVLESAFDTEP- 55
M++++ + R+I + SN Y L F++ ++ S+ +P VT++S ++ ++
Sbjct: 1 MRLFIGRRSRSIVISSNNYCLSFQRLRSIPGASSQQRQLSKTPSVTIKSYPDTDLSSDSN 60
Query: 56 YTQLNHTTFTALFGLITVKGQVFIGIITSNKKVGSPRWKLNEQDKVIEEETIYQILNINF 115
Y ++ F L GL+ + G +++ +I+ + VG PRWKL + +V E+IY++L+++F
Sbjct: 61 YLEVKSCIFNGLLGLVCLNGDIYVAVISGVQNVGFPRWKLIDH-QVRPSESIYKVLDVDF 119
Query: 116 YCIDSDKYDSMFQDLSDIGYERQLTEHPCGHLKMLISDGSFYYSNDFDITNSLQERGLVH 175
Y +++D +D + + S+ Y++ + EHPCG LK L SDG+FYYS DFDI+N ++ GL H
Sbjct: 120 YSLENDVFDYLLCERSEQNYDKLIHEHPCGPLKKLFSDGTFYYSRDFDISNIVKNHGLSH 179
Query: 176 RIEYTIDNQDQRYVWNYNQISEIVQLRSRIAVQERPYFDSGSFLVFLVRGFCQT--ITDG 233
+EYT+DNQD ++WN N SE++ RS+I+ +E+ F + FL F++RG+C+T I DG
Sbjct: 180 NLEYTVDNQDLSFIWNANLASEVINWRSKISNEEKQLFANAGFLTFVIRGYCKTALIEDG 239
Query: 234 ISS-SCTLISRISTEGMNNLSEFKGIDQSGKVSNFVETEIIVQTRRNVFSYTMTGGDIPL 292
++ S T+ISRISTE + E +GI + G+VS FVETEI+V T + +FSYT G IPL
Sbjct: 240 PNTASITIISRISTESKQDTLELEGISEDGRVSLFVETEIVVTTEKFIFSYTQVNGSIPL 299
Query: 293 NWELVEGQFLHGKKPKLLSKASTVQPSFDLHFDELMSKYGVVSIVNVSKPKNDAYEAMIN 352
WE VE Q L+GKK K+ + Q +FD HFD L SKYGVVSIVN+ KPK+++ E +
Sbjct: 300 FWESVESQLLYGKKIKVTKDSIEAQGAFDRHFDNLTSKYGVVSIVNIIKPKSESQEKLAL 359
Query: 353 TYQKCASSKGIDLTLIEDSTSALNRIPHRIIYLLQQKIYEFGSFAYDMDKKIYVGKQTGV 412
TY+ CA SKGI +T IE S+S L + PH+++YLL+Q IYEFG+FAYD+ + IY KQTGV
Sbjct: 360 TYKDCAESKGIKITNIEYSSSVLTKSPHKLLYLLKQDIYEFGAFAYDISRGIYFAKQTGV 419
Query: 413 FRISAVNLFKKLNIVEKVISADVLELTINELEEKDISSDFWKSHDSLWKSNDFWLERLNS 472
RISA + +K N VE+++S +VLELT NE++ +++S F +HD LW N +WL+R +
Sbjct: 420 LRISAFDSIEKPNTVERLVSKEVLELTTNEIDVFELTSPFLDAHDKLWSENYYWLDRTYT 479
Query: 473 KHSKNPSKYKKIYRGLFDPSAIVALYDPLHIYVTRFLRQRRHEYTFEKEISIFAGTFNVN 532
KH+KN KY K+Y LF + V LYDPLHIY++++L+Q R +YTFEK+ISIFAGTFN++
Sbjct: 480 KHTKNSGKYTKVYSKLF--GSRVRLYDPLHIYISQYLKQLRSKYTFEKDISIFAGTFNIS 537
Query: 533 GKLSKEKLEGWLKP-----ENESPDLYVIGLEEIVELSPGHMLATDPYIKTFWEKKLLSE 587
GK+ K+ ++ W+ P E+E DLYVIGLEE+VEL+PGHMLATDPY++ FWEKK+L+
Sbjct: 538 GKIPKDDIKDWIFPKSMSKEDEMADLYVIGLEEVVELTPGHMLATDPYVRQFWEKKILTL 597
Query: 588 INSYN-DKKYHAVFNSQLGGLALLVFTDEENKSRIKHIEGDMKKTGFGGISSNKGAIAVH 646
+N KKY ++++QLGG+ LL+F +E S++KHIEGD+KKTGFGG++SNKGA+AV
Sbjct: 598 LNGPGRKKKYIRLWSTQLGGILLLLFMNETEYSKVKHIEGDVKKTGFGGMASNKGAVAVS 657
Query: 647 LWLSNTKFCFVVSHLSAGLENVEQRHNDYKSIAKHIRFSKGTRIKDHDGVIWMGDFNFRI 706
S T+FC +VSHL+AGLENVEQRHNDYK+IAK IRFSKG RIKDHD +IWMGDFN+RI
Sbjct: 658 FKYSATRFCVLVSHLAAGLENVEQRHNDYKTIAKSIRFSKGLRIKDHDAIIWMGDFNYRI 717
Query: 707 LLSNDDVRQAIIDKNYHRLFEKDQLNQQMISGESFPFFDEMEITFPPTYKFNPGTDVYDT 766
L+SN+DVR+ I+ K Y LFEKDQLNQQMI+GESFP+F EM I FPPTYKF+PGT YDT
Sbjct: 718 LMSNEDVRRKIVSKEYASLFEKDQLNQQMIAGESFPYFHEMAIDFPPTYKFDPGTKNYDT 777
Query: 767 SEKMRIPAWTDRILSRGEILRQELYGSAEDIVFSDHRPVYGLFTAKLTVIDEPKKAKLVA 826
SEKMRIPAWTDRILSRGE+L Q Y EDI+FSDHRPVY +F A++TV+DE KK L
Sbjct: 778 SEKMRIPAWTDRILSRGEVLEQLEYKCCEDILFSDHRPVYAIFRARVTVVDEQKKTTLGT 837
Query: 827 SIKDSINXXXXXXXXXXXXAYLEENDILASKEEYSSS------NPATANEXXXXXXXXXX 880
I + I A L ++ + E S S +P E
Sbjct: 838 QIYEKIMERLEGLDDDEKIAVLSDDAFVIESFEGSDSIAGPTHSPTPIPEPKRGRKLPPP 897
Query: 881 SSDQHKWWVGNGKQAKVSLQVNPKKYILNPERSSNPFQQSE-LPVFMER 928
SSD KWW+G+GKQ KV L V+P Y++NP+R NPF ++E P+F+ER
Sbjct: 898 SSDLKKWWIGSGKQVKVVLDVDPAVYMINPKRDPNPFVENEDEPLFIER 946
>SPBC2G2.02 [U] KOG0566 Inositol-145-triphosphate 5-phosphatase (synaptojanin)
INP51/INP52/INP53 family
Length = 1076
Score = 462 bits (1188), Expect = e-129
Identities = 297/980 (30%), Positives = 481/980 (48%), Gaps = 83/980 (8%)
Query: 1 MKVYLRKSPRAIALVSNGYVLIFEKRQNSTSSFLKGGSPKVTVQSVLESAFDTEPYTQLN 60
M+ LR+ PR++ALV+ + L+F + +S + S E + +++
Sbjct: 1 MQCLLREKPRSLALVNKDHALMFHSVPQNKNSL-----SVCVAEFTALSEKPLEGFRKIS 55
Query: 61 HTTFTALFGLITVKGQVFIGIITSNKKVGSPRWKLNEQDKVIEEETIYQILNINFYCIDS 120
GLI ++G F+ +I+ +V +V ++E +++I+ + FY ++
Sbjct: 56 SHRIYGTLGLIELEGSNFLCVISGASEVA----------RVRDKERVFRIMEVCFYSVNR 105
Query: 121 DKYDSMFQ-----------DLSDIGYER-QLTEHPCGHLKMLISDGSFYYSNDFDITNSL 168
+D + Q D GY+ + P L+ L+++GSFY+S DFDIT L
Sbjct: 106 SNWDHIRQENYSPDIPDGYDTDTQGYDSYKYAAEPFSSLRKLLTNGSFYFSLDFDITTRL 165
Query: 169 QERGLVHRIEYTIDNQDQRYVWNYNQISEIVQLRSRIAVQERPYFDSGSFLVFLVRGFCQ 228
Q R E D+ +++WN + ++++ RS + E+ D F +RGF
Sbjct: 166 QLRTSQTMTEPQYDSMHTQFMWNEFMLRQLIKFRSHLNGDEKSALDGCRFFTCAIRGFAS 225
Query: 229 T--ITDGISS-SCTLISRISTEGMNNLSEFKGIDQSGKVSNFVETEIIVQTRRNVFSYTM 285
T GI + +LISR+S+ +G+D G V+NFVETE I+ + + SY
Sbjct: 226 TEQFKLGIQTIRLSLISRLSSLRAGTRFLSRGVDDDGNVANFVETETILDSSKYCVSYCQ 285
Query: 286 TGGDIPLNWELVEGQFLHGKKPKLLSKASTVQPSFDLHFDELMSKYGVVSIVNV---SKP 342
G IP+ WE EG + G+K + + +F+ HF L+ +YG V I+N+
Sbjct: 286 VRGSIPIFWEQ-EGVQMFGQKIDITRSLEATRAAFEKHFTSLIEEYGPVHIINLLGTGSG 344
Query: 343 KNDAYEAMINTYQKCASSKGIDLTLIEDSTSALN-RIPHRIIYLLQQKIYEFGSFAYDMD 401
+ E + Q I LT + + + ++I ++ FG F ++ +
Sbjct: 345 ERSLSERLRQHIQLSPEKDLIHLTEFDYHSQIRSFEDANKIRPMIYSDAETFG-FYFENN 403
Query: 402 KKIYVGKQTGVFRISAVNLFKKLNIVEKVISADVLELTINELEEKDISSDFWKSHDSLWK 461
+ + Q GVFR + ++ + N+++ ++S LE + ++ DFW+ H ++W
Sbjct: 404 EGQSIVVQDGVFRTNCLDCLDRTNVIQNLVSRVFLE-QVMIYTRQNAGYDFWQVHSTIWA 462
Query: 462 SNDFWLERL-----------------------------------NSKHSKNPSKYKKIYR 486
+N L R+ N+ K + +
Sbjct: 463 NNGDALARIYTGTGALKSSFTRKGKLSIAGALNDLSKSVGRMYINNFQDKGRQETIDLLL 522
Query: 487 GLFDPSAIVALYDPLHIYVTRFLRQRRHEYTFEKEISIFAGTFNVNGKLSKEKLEGWLKP 546
G V LYDP+H YV LR+R +E++ K + IF ++N+NG + KLE WL P
Sbjct: 523 GRLIDQHPVILYDPIHEYVNHELRKRENEFSEHKNVKIFVASYNLNGCSATTKLENWLFP 582
Query: 547 ENES-PDLYVIGLEEIVELSPGHMLATDPYIKTFWEKKLLSEINSY--NDKKYHAVFNSQ 603
EN D+YV+G +EIV+L+P +++ DP + WE + +N + Y + + Q
Sbjct: 583 ENTPLADIYVVGFQEIVQLTPQQVISADPAKRREWESCVKRLLNGKCTSGPGYVQLRSGQ 642
Query: 604 LGGLALLVFTDEENKSRIKHIEGDMKKTGFGGISSNKGAIAVHLWLSNTKFCFVVSHLSA 663
L G AL++F E IK++EG +KKTG GG+S NKGA+A+ +T CF+ SHL+A
Sbjct: 643 LVGTALMIFCKESCLPSIKNVEGTVKKTGLGGVSGNKGAVAIRFDYEDTGLCFITSHLAA 702
Query: 664 GLENVEQRHNDYKSIAKHIRFSKGTRIKDHDGVIWMGDFNFRILLSNDDVRQAIIDKNYH 723
G N ++R +DY++IA +RF +G I +HD V+W GDFN+RI L+ ++V I
Sbjct: 703 GYTNYDERDHDYRTIASGLRFRRGRSIFNHDYVVWFGDFNYRISLTYEEVVPCIAQGKLS 762
Query: 724 RLFEKDQLNQQMISGESFPFFDEMEITFPPTYKFNPGTDVYDTSEKMRIPAWTDRILSRG 783
LFE DQLN+QM++G+ FPFF E+ ITFPPTYKF+ GTD+YDTS+K R+PAWTDRIL RG
Sbjct: 763 YLFEYDQLNKQMLTGKVFPFFSELPITFPPTYKFDIGTDIYDTSDKHRVPAWTDRILYRG 822
Query: 784 EILRQELYGSAEDIVFSDHRPVYGLFTAKLTVIDEPKKAKLVASIKDSINXXXXXXXXXX 843
E++ + + +SDHRP+Y + A + +D KK L + +
Sbjct: 823 ELVPHSY--QSVPLYYSDHRPIYATYEANIVKVDREKKKILFEELYNQ-RKQEVRDASQT 879
Query: 844 XXAYLEENDILASKEEYSSSNPATANEXXXXXXXXXXSSDQHKWWVGNGKQAKVSLQVNP 903
++ +A K PA + SS++ KWW +G AK
Sbjct: 880 SYTLIDIAGSVAGKPNLIPHLPANGVD-----KIKQPSSERSKWWFDDGLPAKSIAAPPG 934
Query: 904 KKYILNPERSSNPFQQSELP 923
+Y LNP R NPF+ + P
Sbjct: 935 PEYRLNPSRPINPFEPTAEP 954
>YNL106c [U] KOG0566 Inositol-145-triphosphate 5-phosphatase (synaptojanin)
INP51/INP52/INP53 family
Length = 1183
Score = 453 bits (1166), Expect = e-127
Identities = 289/922 (31%), Positives = 454/922 (48%), Gaps = 116/922 (12%)
Query: 1 MKVYLRKSP-RAIALVSNGYVLIFEKRQNSTSSFLKGGSPKVTVQSVLESAFDTEPYTQL 59
MK+ L K R IA+VS + L+F + S V+ V ++ + + +L
Sbjct: 1 MKILLSKQQTRKIAIVSETHGLVFRPINSKNSR-----RSTCAVELVPKAELNGNGFRRL 55
Query: 60 NHTTFTALFGLITVKGQVFIGIITSNKKVGSPRWKLNEQDKVIEEETIYQILNINFYCID 119
++ GLI ++G +FI IT KV P I +T+ +I ++F+C++
Sbjct: 56 SNHEIYGFIGLIEIEGLMFIATITGKSKVAQP----------IPNKTVNKIYAVDFFCLN 105
Query: 120 SDKYDSMFQDLSDIGY------------------------------------ERQLTEHP 143
+ K+D F D+ GY + Q +HP
Sbjct: 106 NSKWD--FMDIDSSGYPIVTNDGDFAISSPPSISTHSSRSSLRSSSSRSLNAQEQAPKHP 163
Query: 144 CGHLKMLISDGSFYYSNDFDITNSLQERGLVHRIEYTIDNQDQRYVWNYNQISEIVQLRS 203
C L+ L+S+GSFYYS DFD+T +LQ+RG + D+ D+ ++WN + EI+ R
Sbjct: 164 CHELRKLLSNGSFYYSTDFDLTCTLQKRGFTEH-SLSFDDFDREFMWNSFLMDEIITYRD 222
Query: 204 RIAVQERPYFDSGSFLVFLVRGFCQTITDGISS---SCTLISRISTEGMNNLSEFKGIDQ 260
R+ V + D FL ++RGF +TI I+ T+ISR S + +GID
Sbjct: 223 RLDVTAKELLDQRGFLTTVIRGFAETIFSYINRLKVGLTIISRQSWKRAGTRFNARGIDD 282
Query: 261 SGKVSNFVETEIIVQTRRNVFSYTMTGGDIPLNWELVEGQFLHGKKPKLLSKASTVQPSF 320
G V+NFVETE+I+ + + +++T G +P+ WE + L K ++ QP+F
Sbjct: 283 DGHVANFVETEMIMYSSQYCYAFTQIRGSLPIFWE--QDTSLISPKIQITRSVEATQPTF 340
Query: 321 DLHFDELMSKYGVVSIVNVSKPKNDA------YEAMINTYQKCASSKGIDLTLIE---DS 371
D HF L KYG V I+N+ K+ Y+ + +K + + LT + ++
Sbjct: 341 DEHFIRLFKKYGPVHIINLLSTKSSEIQLSRRYKEQLKNSEKMKIGRDVFLTSFDFHRET 400
Query: 372 TSALNRIPHRIIYLLQQKIYEFGSFAYDMDKKIYVGKQTGVFRISAVNLFKKLNIVEKVI 431
+ RII ++ I + G F+YD+ + + +Q GVFR + ++ + N++++ I
Sbjct: 401 SQDGFAAASRIIPKIRNTILDAGYFSYDVKEGRLISEQDGVFRTNCLDCLDRTNLIQQTI 460
Query: 432 SADVLELTINELEEKDISS-----DFWKSHDSLWKSNDFWLERL----NSKHSKNPSKYK 482
S V +L + + SS +F + ++LW N + ++ N+ S K K
Sbjct: 461 SLAVFKLFLEDFRLVKPSSFIDDNEFVQKVNALWADNGDQISQIYTGTNALKSSYSRKGK 520
Query: 483 KIYRGLFDPSA-------------------------------IVALYDPLHIYVTRFLRQ 511
+ G + +V LYDP+ YV L +
Sbjct: 521 MSFSGALSDATKSVSRMYINNFVDKGKQQNIDTLLGKLPHQQVVELYDPICEYVNERLLE 580
Query: 512 RRHEYTFEKEISIFAGTFNVNGKLSKEKLEGWLKPENES--PDLYVIGLEEIVELSPGHM 569
++T I++F GTFNVNG + L WL P + PD+ V+GL+E++EL+ G +
Sbjct: 581 SEEKFTTHSNINLFVGTFNVNGNSRRADLSKWLFPIGDKFKPDVVVLGLQEVIELTAGSI 640
Query: 570 LATDPYIKTFWEKKLLSEINSYNDKKYHAVFNSQLGGLALLVFTDEENKSRIKHIEGDMK 629
L D +FWE + +N Y ++KY + Q+ L +L F + IK + G K
Sbjct: 641 LNADYTKSSFWETMVTDCLNQY-EEKYLLLRVEQMSSLLILFFARSDRAYNIKEVGGSTK 699
Query: 630 KTGFGGISSNKGAIAVHLWLSNTKFCFVVSHLSAGLENVEQRHNDYKSIAKHIRFSKGTR 689
KTGFGGI+ NKGA+A+ T FCFV +HLSAG N+++R NDY +I ++I F +
Sbjct: 700 KTGFGGITGNKGAVAIRFDYGATSFCFVNTHLSAGASNIDERRNDYNNIYRNITFPRSKT 759
Query: 690 IKDHDGVIWMGDFNFRILLSNDDVR---QAIIDKNYHRLFEKDQLNQQMISGESFPFFDE 746
I HD + W+GD N+RI L+ND+VR +A D RL + DQL Q++ G F F E
Sbjct: 760 IPHHDSLFWLGDLNYRITLTNDEVRRELRAQKDGYIDRLLQYDQLTQEINEGVVFQGFKE 819
Query: 747 MEITFPPTYKFNPGTDVYDTSEKMRIPAWTDRILSRGEILRQELYGSAEDIVFSDHRPVY 806
+ F PTYK++ GTD YDTSEK R P+WTDRI+ +GE L Y A + SDH+PVY
Sbjct: 820 PTLQFRPTYKYDYGTDNYDTSEKARTPSWTDRIIYKGENLHPLAYSDA-PLKISDHKPVY 878
Query: 807 GLFTAKLTVIDEPKKAKLVASI 828
+ A + +DE +K LV +
Sbjct: 879 AAYRANVKFVDEKEKLNLVEKL 900
>YOR109w [U] KOG0566 Inositol-145-triphosphate 5-phosphatase (synaptojanin)
INP51/INP52/INP53 family
Length = 1107
Score = 437 bits (1123), Expect = e-122
Identities = 274/892 (30%), Positives = 444/892 (49%), Gaps = 89/892 (9%)
Query: 1 MKVYLRKSP-RAIALVSNGYVLIFEKRQNSTSSFLKGGSPKVTVQSVLESAFDTEPYTQL 59
M +++ + P R +A+VSN Y L+ + S P ++ + ++ + +L
Sbjct: 1 MIIFVSEEPERRLAIVSNLYALVLKPVGKKPSD-----KPLCAIELLQKNDLKKYGFKRL 55
Query: 60 NHTTFTALFGLITVKGQVFIGIITSNKKVGSPRWKLNEQDKVIEEETIYQILNINFYCID 119
+ GLI V G +F+G IT KV P ET+ +I ++F+C++
Sbjct: 56 TSHEIFGVIGLIEVNGLLFVGAITGKSKVAQP----------CPGETVNKIFAVDFFCLN 105
Query: 120 SDKYDSMFQDLS---------DIGYERQLTEHPCGHLKMLISDGSFYYSNDFDITNSLQE 170
+ +D + D S Y+ L +HPC LK L+S+GSFYYS+DFD+T++LQ
Sbjct: 106 DNSWDFIEIDSSGYPVLPETASTEYQDALPKHPCYELKKLLSNGSFYYSSDFDLTSTLQH 165
Query: 171 RGLVHRIEYTIDNQDQRYVWNYNQISEIVQLRSRIAVQERPYFDSGSFLVFLVRGFCQTI 230
RG + D ++ Y+WN + E++ R + + D FL ++RGF +T
Sbjct: 166 RGYGQH-SLSTDTYEEEYMWNSFLMQEMITYRDHLDTNLKQILDDEGFLTTVIRGFAETF 224
Query: 231 TDGISS---SCTLISRISTEGMNNLSEFKGIDQSGKVSNFVETEIIVQTRRNVFSYTMTG 287
+ + T+IS+ S + +G+D V+NFVETE I+ + + +++T
Sbjct: 225 VSYVKKLKVALTIISKQSWKRAGTRFNARGVDDEANVANFVETEFIMYSSQYCYAFTQIR 284
Query: 288 GDIPLNWELVEGQFLHGKKPKLLSKASTVQPSFDLHFDELMSKYGVVSIVNVSKPKND-- 345
G IP+ WE +G L + ++ QP FD H + + KYG V +VN+ K+
Sbjct: 285 GSIPVFWE--QGTSLINPRVQITRSFEATQPVFDKHIMKSVEKYGPVHVVNLLSTKSSEI 342
Query: 346 ----AYEAMINTYQKCASSKGIDLTLI----EDSTSALNRIPHRIIYLLQQKIYEFGSFA 397
Y+ + +K +K I LT E S + + ++I L+ + G ++
Sbjct: 343 ELSKRYKEHLTHSKKLNFNKDIFLTEFDFHKETSQEGFSGV-RKLIPLILDSLLSSGYYS 401
Query: 398 YDMDKKIYVGKQTGVFRISAVNLFKKLNIVEKVISADVLELTINELEEKDISS-----DF 452
YD+ +K + +Q G+FR + ++ + N+ +++IS + + +S DF
Sbjct: 402 YDVREKKNISEQHGIFRTNCLDCLDRTNLAQQIISLAAFRTFLEDFRLISSNSFIDDDDF 461
Query: 453 WKSHDSLWKSNDFWLERL----NSKHSKNPSKYKKIYRGLFDPSA--------------- 493
H++LW + + ++ N+ S K K G +
Sbjct: 462 VSKHNTLWADHGDQISQIYTGTNALKSSFSRKGKMSLAGALSDATKSVSRIYINNFMDKE 521
Query: 494 ----------------IVALYDPLHIYVTRFLRQRRHEYTFEKEISIFAGTFNVNGKLSK 537
V LYDP++ YV+ L+ ++T I++ G+FNVNG K
Sbjct: 522 KQQNIDTLLGRLPYQKAVQLYDPVNEYVSTKLQSMSDKFTSTSNINLLIGSFNVNGATKK 581
Query: 538 EKLEGWLKP--ENESPDLYVIGLEEIVELSPGHMLATDPYIKTFWEKKLLSEINSYNDKK 595
L WL P E PD+ V+GL+E++ELS G +L D +FWE + +N Y+D K
Sbjct: 582 VDLSKWLFPIGEKFKPDIVVLGLQEVIELSAGSILNADYSKSSFWENLVGDCLNQYDD-K 640
Query: 596 YHAVFNSQLGGLALLVFTDEENKSRIKHIEGDMKKTGFGGISSNKGAIAVHLWLSNTKFC 655
Y + Q+ L +L F + +K +EG KKTGF G++ NKGA+++ T FC
Sbjct: 641 YLLLRVEQMTSLLILFFVKADKAKYVKQVEGATKKTGFRGMAGNKGAVSIRFEYGATSFC 700
Query: 656 FVVSHLSAGLENVEQRHNDYKSIAKHIRFSKGTRIKDHDGVIWMGDFNFRILLSNDDVRQ 715
FV SHL+AG NVE+R +DY+SI + I F++ I HD + W+GD N+RI L N+DVR+
Sbjct: 701 FVNSHLAAGATNVEERRSDYESIVRGITFTRTKMIPHHDSIFWLGDMNYRINLPNEDVRR 760
Query: 716 AIIDKN---YHRLFEKDQLNQQMISGESFPFFDEMEITFPPTYKFNPGTDVYDTSEKMRI 772
++++ +L DQL + SG F F E + F PTYK++PGT YD+SEK R
Sbjct: 761 ELLNQEEGYIDKLLHFDQLTLGINSGSVFEGFKEPTLKFRPTYKYDPGTGTYDSSEKERT 820
Query: 773 PAWTDRILSRGEILRQELYGSAEDIVFSDHRPVYGLFTAKLTVIDEPKKAKL 824
P+WTDRI+ +GE L Y A I+ SDHRPVY + AK+T +D+ ++ L
Sbjct: 821 PSWTDRIIYKGENLLPLSYSDA-PIMISDHRPVYAAYRAKITFVDDKERLSL 871
>SPBC577.13 [U] KOG0566 Inositol-145-triphosphate 5-phosphatase (synaptojanin)
INP51/INP52/INP53 family
Length = 889
Score = 298 bits (764), Expect = 2e-80
Identities = 244/908 (26%), Positives = 418/908 (45%), Gaps = 117/908 (12%)
Query: 1 MKVYLRKSPRAIALVSNGYVLIFEKRQNSTSSFLKGGSPKVTVQSVLESAFDTEPYTQLN 60
M+ YL++ R++A ++ Y I +K S + + + E + ++
Sbjct: 1 MQCYLKRKERSVAFITEKYAAIIQKPSVKDSDCI-----------ITFTCISLEEFEKIK 49
Query: 61 HTTFTALFGLITVKGQV-FIGIITSNKKVGSPRWKLNEQDKVIE---EETIYQILNINFY 116
+ LFG + G + + + K G + V+ + I ++ N++F
Sbjct: 50 E--YELLFGGEKILGTLGLFNYVCEDMKEGVFLCVARKAKLVLRIGNRDPISKLENVSFI 107
Query: 117 CIDSDKYDS-MFQ-----------------DLSDIGYERQLTE---------------HP 143
+D + +D +F+ DL++I + + H
Sbjct: 108 SLDQELWDEELFEPMPRNSSPSSTFSTSTSDLNNIEKDNLVNSEYSSKYSSTTRIYPYHS 167
Query: 144 CGHLKMLISDGSFYYSNDFDITNSLQERGLVHRIEYTIDNQDQRYVWNYNQISEIVQLRS 203
L L++DGSFY S + + Q E +D Y WN I+E+ S
Sbjct: 168 LSQLTDLLTDGSFYVSTNISCFSRFQS-------EQPYGPKDI-YCWNRFLITELDNHFS 219
Query: 204 RIAVQERPYFDSGSFLVFLVRGFCQTITDGISSSCTLISRISTEGMNNLSEFKGIDQSGK 263
+ E+ + L+ RG+ + + S S ++IS++S+ G GID S
Sbjct: 220 EAHILEK----FPNLLLHCFRGYVERMFID-SMSMSIISKVSSYGSRQTYPPSGIDDSSY 274
Query: 264 VSNFVETEIIVQTRRNVFSYTMTGGDIPLNWELVEGQFLHGKKPKLLSKASTVQPSFDLH 323
S FVETE IV+ + VFS+ G +P WE + +G L + Q F+ H
Sbjct: 275 CSMFVETEFIVEIAQTVFSFVQVRGTVPCFWEEQFSSW-YGPSISFLRSSQASQSLFNFH 333
Query: 324 FDELMSKYGVVSIVNVSKPKN------DAYEAMINTYQKCASSKGIDLTLIEDSTSALNR 377
F +L YG + ++++ + K +AY+ + A K T A
Sbjct: 334 FSKLYKAYGDIYVIDLLQTKGFEASLYEAYKHHLMLLPFPAVVKKFHFT----PDPARPD 389
Query: 378 IPHRIIYLLQQKIYEFGSFAYDMDKKIYVGKQTGVFRISAVNLFKKLNIVEKVISADVLE 437
I R+ L + E G ++ + Q GVFRI+ ++ + N+++ IS VL+
Sbjct: 390 IDPRLETDLADDLKEMGYTQKSIENDMLESFQKGVFRINDLDCLGRTNVIQYQISRLVLK 449
Query: 438 LTINELEEKDISSDFWKSHDSLWKSNDFWLERL-------NSKHSKNPSK---------- 480
L+ ++ + + LW +N + +L S ++ K
Sbjct: 450 DIFFNLQI-GVTFNILEYLRHLWSNNGDAIAKLITGVGSIGSSATRRGRKSIAGSLSDIS 508
Query: 481 --YKKIY----------------RGLFDPSAIVALYDPLHIYVTRFLRQRRHEYTFEKEI 522
+ ++Y G F + V + + + Y+ LRQRR EY E++
Sbjct: 509 KSFGRMYVGRYPDVESQNAILLLLGCFPNQSPVLISESVSSYIQGVLRQRRSEYRVERDF 568
Query: 523 SIFAGTFNVNGKL-SKEKLEGWLKPENESP---DLYVIGLEEIVELSPGHMLATDPYIKT 578
SIF+ TFN NGK+ S ++ + L P E DLYV+ ++EI+ L+ H++++
Sbjct: 569 SIFSSTFNANGKVPSTDEFKRLLLPFGERTSAYDLYVVAVQEIITLNMSHLVSSSNQKLR 628
Query: 579 FWEKKLLSEINSYN-DKKYHAVFNSQLGGLALLVFTDEENKSRIKHIEGDMKKTGFGGIS 637
WE+K+L +NS + + KY + + Q+ G+ L VF +++ + + +KTGFGG S
Sbjct: 629 IWEEKILMILNSRDSNNKYMLISSIQMAGVFLGVFIRKDDHLVVSKVTKTTRKTGFGGFS 688
Query: 638 SNKGAIAVHLWLSNTKFCFVVSHLSAGLENVEQRHNDYKSIAKHIRFSKGTRIKDHDGVI 697
+NKGA+A+ + + ++ FCFV SH + + N+ +R+ +Y SI+ ++ F G +I DH ++
Sbjct: 689 ANKGAVAIEMNVCDSDFCFVSSHFAPKVNNISERNMEYTSISDNLVFPSGMKIYDHTNIL 748
Query: 698 WMGDFNFRILLSNDDVRQAIIDKNYHRLFEKDQLNQQMISGESFPFFDEMEITFPPTYKF 757
WMGDFN+RI N++VR+ + + +L DQL +M G F E ++TF PTYKF
Sbjct: 749 WMGDFNYRIDSDNEEVRKLVELDDLDKLASYDQLCTEMKKGTVFHGLVEPQLTFLPTYKF 808
Query: 758 NPGTDVYDTSEKMRIPAWTDRILSRGEILRQELYGSAEDIVFSDHRPVYGLFTAKLTVID 817
+ GT+ YDTS+K R+P+WTDRIL+ R Y S DI SDHRPV+ F+ K+
Sbjct: 809 DNGTNDYDTSDKQRVPSWTDRILATKSFTR-NCYKSC-DIRCSDHRPVFATFSLKIFSTC 866
Query: 818 EPKKAKLV 825
KKA ++
Sbjct: 867 MDKKAGII 874
>CE28239 [U] KOG0566 Inositol-145-triphosphate 5-phosphatase (synaptojanin)
INP51/INP52/INP53 family
Length = 1113
Score = 250 bits (639), Expect = 6e-66
Identities = 216/764 (28%), Positives = 343/764 (44%), Gaps = 110/764 (14%)
Query: 147 LKMLISDGSFYYSN--DFDITNSLQERGLVHRIEYTIDNQDQRYVWNYNQISEIVQLRSR 204
L+ L+S FY+S+ +D+T S Q R + D D R+ WN RS
Sbjct: 119 LQRLLSSQMFYFSSLQSYDLTRSAQHRD-------SHDCSDARFFWN----------RSL 161
Query: 205 IAVQERPYFDSGSFLVFLVRG--FCQTITDGISSS-CTLISRISTEGMNNLSEFKGIDQS 261
+R D+ ++L+ + G + + G ++ LISR+S E + +G +
Sbjct: 162 HFSFQRYGIDTDNWLLKCMAGSVLVRVVYVGANTGRVALISRLSCERVGTRFNVRGANYL 221
Query: 262 GKVSNFVETEIIVQTRRNVFSYTMTGGDIPLNWELVEGQFLHGKKPKLLSKASTVQPSFD 321
G V+NFVETE ++ S G IPL WE G + K KL + +++ P++
Sbjct: 222 GNVANFVETEQLLLFDEKECSLLQIRGSIPLFWEQ-PGVNVGSHKVKLRAFETSL-PAYH 279
Query: 322 LHFDELMSKYGVVSIVNVSKPKN------DAYEAMINTYQKCASSKGIDLTLIEDSTSAL 375
H +L +YG +IVN+ K DA++ Q +S + I+ A
Sbjct: 280 RHLSQLQHRYGEFAIVNLLGRKEGERVLGDAFKT-----QHKSSHFAPLVDFIDFDYHAQ 334
Query: 376 NRIPHRIIYLLQQKIYEFGS---FAYDMDKKIYVGKQTGVFRISAVNLFKKLNIVEKVIS 432
+I I L++K+ + F Y M K+I V +QTGV R + ++ + N V+ I
Sbjct: 335 MKISKEAIVQLKKKMSPHMTKHGFFYSMGKEI-VKRQTGVIRTNCLDCLDRTNAVQTAIG 393
Query: 433 AD-----VLELTIN------ELEEKDISSDFWKSHDSLWKSNDFWLERLNSKHSKNPSKY 481
V L +N E ++I D W+ + + L+ K SK
Sbjct: 394 LQMSHDQVAFLNLNAGKVNVEQRVEEILRDLWQKNGDQCSTIYAGTGALDGK-----SKL 448
Query: 482 KKIYRGL----------------FDPSAIVALYDPL----------------HIYVTRFL 509
K R L FD A YDP + L
Sbjct: 449 KDASRSLARTIQNNLMDGAKQESFDLFLTGAAYDPRLFDRACNILPPSLIQEYADAVSQL 508
Query: 510 RQRRHEYTFEKEISIFAGTFNVNGKLS--------KEKLEGWL----------KPENESP 551
+R E + I IF GT+NVNG + + L W+ + +
Sbjct: 509 VERSPEIAEPQSIKIFVGTWNVNGGKNIHNVAFRNESSLSHWIFANSMTRLVSVEDEQLA 568
Query: 552 DLYVIGLEEIVELSPGHMLATDPYIKTFWEKKLLSEINSYNDKKYHAVFNSQLGGLALLV 611
D+ IG+EE+V+L+ +M+ + W + + ++ + + + QL G+ L +
Sbjct: 569 DIVAIGVEELVDLNASNMVKASTTNQRMWCESIRKTLSE--KAPFVLIGSEQLVGVCLFL 626
Query: 612 FTDEENKSRIKHIEGDMKKTGFGGISSNKGAIAVHLWLSNTKFCFVVSHLSAGLENVEQR 671
F +K KTG GG + NKG++A + + +T CF+ SH +AG + R
Sbjct: 627 FARPRVSPYLKDFAVASVKTGMGGATGNKGSVAFRIVVFSTSICFICSHFAAGQNEIRDR 686
Query: 672 HNDYKSIAKHIRFSKGTRIKDHDGVIWMGDFNFRILLSNDDVRQAIIDKNYHRLFEKDQL 731
+ D+ + K IRF G I HD + W+GDFN+RI LS D+V+ A+ + +Y +L E DQL
Sbjct: 687 NEDFATTLKKIRFPLGREIDSHDVIFWLGDFNYRINLSGDEVKNAVRNGDYAKLVENDQL 746
Query: 732 NQQMISGESFPFFDEMEITFPPTYKFNPGTDVYDTSEKMRIPAWTDRIL---SRGEILRQ 788
QQ G++F F+E ++TF PTYK++ +D YDTSEK R PAWTDRIL R + Q
Sbjct: 747 TQQKALGQTFVGFNEGQLTFAPTYKYDTFSDDYDTSEKCRAPAWTDRILWKDQRKKGKTQ 806
Query: 789 ELYGSAEDIVFSDHRPVYGLFTAKLTVIDEPKKAKLVASIKDSI 832
L ++ SDHRPV +F + + K +L+ + +S+
Sbjct: 807 LLSYDRSELKTSDHRPVGAVFKVETFKVGGRKCVELIEDVVESM 850
>CE29050 [U] KOG0566 Inositol-145-triphosphate 5-phosphatase (synaptojanin)
INP51/INP52/INP53 family
Length = 1119
Score = 250 bits (638), Expect = 8e-66
Identities = 218/770 (28%), Positives = 344/770 (44%), Gaps = 116/770 (15%)
Query: 147 LKMLISDGSFYYSN--DFDITNSLQERGLVHRIEYTIDNQDQRYVWNYNQISEIVQLRSR 204
L+ L+S FY+S+ +D+T S Q R + D D R+ WN RS
Sbjct: 119 LQRLLSSQMFYFSSLQSYDLTRSAQHRD-------SHDCSDARFFWN----------RSL 161
Query: 205 IAVQERPYFDSGSFLVFLVRG--FCQTITDGISSS-CTLISRISTEGMNNLSEFKGIDQS 261
+R D+ ++L+ + G + + G ++ LISR+S E + +G +
Sbjct: 162 HFSFQRYGIDTDNWLLKCMAGSVLVRVVYVGANTGRVALISRLSCERVGTRFNVRGANYL 221
Query: 262 GKVSNFVETEIIVQTRRNVFSYTMTGGDIPLNWELVEGQFLHGKKPKLLSKASTVQPSFD 321
G V+NFVETE ++ S G IPL WE G + K KL + +++ P++
Sbjct: 222 GNVANFVETEQLLLFDEKECSLLQIRGSIPLFWEQ-PGVNVGSHKVKLRAFETSL-PAYH 279
Query: 322 LHFDELMSKYGVVSIVNVSKPKN------DAYEAMINTYQKCASSKGIDLTLIEDSTSAL 375
H +L +YG +IVN+ K DA++ Q +S + I+ A
Sbjct: 280 RHLSQLQHRYGEFAIVNLLGRKEGERVLGDAFKT-----QHKSSHFAPLVDFIDFDYHAQ 334
Query: 376 NRIPHRIIYLLQQKIYEFGS---FAYDMDKKIYVGKQTGVFRISAVNLFKKLNIVEKVIS 432
+I I L++K+ + F Y M K+I V +QTGV R + ++ + N V+ I
Sbjct: 335 MKISKEAIVQLKKKMSPHMTKHGFFYSMGKEI-VKRQTGVIRTNCLDCLDRTNAVQTAIG 393
Query: 433 AD-----VLELTIN------ELEEKDISSDFWKSHDSLWKSNDFWLERLNSKHSKNPSKY 481
V L +N E ++I D W+ + + L+ K SK
Sbjct: 394 LQMSHDQVAFLNLNAGKVNVEQRVEEILRDLWQKNGDQCSTIYAGTGALDGK-----SKL 448
Query: 482 KKIYRGL----------------FDPSAIVALYDP--------------------LHIYV 505
K R L FD A YDP H Y
Sbjct: 449 KDASRSLARTIQNNLMDGAKQESFDLFLTGAAYDPRLFDRACNILPPSLIQESYYYHEYA 508
Query: 506 TRF--LRQRRHEYTFEKEISIFAGTFNVNGKLS--------KEKLEGWL----------K 545
L +R E + I IF GT+NVNG + + L W+
Sbjct: 509 DAVSQLVERSPEIAEPQSIKIFVGTWNVNGGKNIHNVAFRNESSLSHWIFANSMTRLVSV 568
Query: 546 PENESPDLYVIGLEEIVELSPGHMLATDPYIKTFWEKKLLSEINSYNDKKYHAVFNSQLG 605
+ + D+ IG+EE+V+L+ +M+ + W + + ++ + + + QL
Sbjct: 569 EDEQLADIVAIGVEELVDLNASNMVKASTTNQRMWCESIRKTLSE--KAPFVLIGSEQLV 626
Query: 606 GLALLVFTDEENKSRIKHIEGDMKKTGFGGISSNKGAIAVHLWLSNTKFCFVVSHLSAGL 665
G+ L +F +K KTG GG + NKG++A + + +T CF+ SH +AG
Sbjct: 627 GVCLFLFARPRVSPYLKDFAVASVKTGMGGATGNKGSVAFRIVVFSTSICFICSHFAAGQ 686
Query: 666 ENVEQRHNDYKSIAKHIRFSKGTRIKDHDGVIWMGDFNFRILLSNDDVRQAIIDKNYHRL 725
+ R+ D+ + K IRF G I HD + W+GDFN+RI LS D+V+ A+ + +Y +L
Sbjct: 687 NEIRDRNEDFATTLKKIRFPLGREIDSHDVIFWLGDFNYRINLSGDEVKNAVRNGDYAKL 746
Query: 726 FEKDQLNQQMISGESFPFFDEMEITFPPTYKFNPGTDVYDTSEKMRIPAWTDRIL---SR 782
E DQL QQ G++F F+E ++TF PTYK++ +D YDTSEK R PAWTDRIL R
Sbjct: 747 VENDQLTQQKALGQTFVGFNEGQLTFAPTYKYDTFSDDYDTSEKCRAPAWTDRILWKDQR 806
Query: 783 GEILRQELYGSAEDIVFSDHRPVYGLFTAKLTVIDEPKKAKLVASIKDSI 832
+ Q L ++ SDHRPV +F + + K +L+ + +S+
Sbjct: 807 KKGKTQLLSYDRSELKTSDHRPVGAVFKVETFKVGGRKCVELIEDVVESM 856
>7291368 [U] KOG0566 Inositol-145-triphosphate 5-phosphatase (synaptojanin)
INP51/INP52/INP53 family
Length = 1218
Score = 244 bits (622), Expect = 6e-64
Identities = 215/790 (27%), Positives = 350/790 (44%), Gaps = 139/790 (17%)
Query: 141 EHPCGHLKMLISDGSFYYSND-------------FDITNSLQERGLVHRIEYTIDNQDQR 187
E ++ L++ G+FY+++ FDIT Q R D R
Sbjct: 114 EDKISEVRKLLNSGTFYFAHTNASASASGASSYRFDITLCAQRR-------QQTQETDNR 166
Query: 188 YVWNYNQISEIVQLRSRIAVQERPYFDSGSFLVFLVRGFCQTITDGISSS---CTLISRI 244
+ WN ++ I +R I D S+L+ + G + T I + +ISR+
Sbjct: 167 FFWN--RMMHIHLMRFGI--------DCQSWLLQAMCGSVEVRTVYIGAKQARAAIISRL 216
Query: 245 STEGMNNLSEFKGIDQSGKVSNFVETEIIVQTRRNVFSYTMTGGDIPLNWELVEGQFLHG 304
S E +G + G V+NFVETE ++ +V SY T G +PL WE G +
Sbjct: 217 SCERAGTRFNVRGTNDEGYVANFVETEQVIYVDGDVTSYVQTRGSVPLFWEQ-PGVQVGS 275
Query: 305 KKPKLLSKASTVQPSFDLHFDELMSKYGVVSIVNV---SKPKNDAYEAMI-NTYQK---C 357
K KL T +FD H + +YG ++VN+ S + EAM+ N +Q+
Sbjct: 276 HKVKLSRGFETSAAAFDRHMSMMRQRYGYQTVVNLLGSSLVGSKEGEAMLSNEFQRHHGM 335
Query: 358 ASSKGIDLTLIE-------DSTSALNRIPHRIIYLLQQKIYEFGSFAYDMDKKIYVGKQT 410
++ K + + + + SAL ++ RI+ +G F + + +Q
Sbjct: 336 SAHKDVPHVVFDYHQECRGGNFSALAKLKERIVACGAN----YGVFHASNGQVLR--EQF 389
Query: 411 GVFRISAVNLFKKLNIVEKVISADVLELTINELE---EKDISSDFWKSHDSLWKSNDFWL 467
GV R + ++ + N V+ + D L + + L+ ++ S F + +W +N +
Sbjct: 390 GVVRTNCLDCLDRTNCVQTYLGLDTLGIQLEALKMGGKQQNISRFEEIFRQMWINNGNEV 449
Query: 468 ERLNS-----------------------KHSKNPSKYKKI---------YRGLFDPSAIV 495
++ + + + SK + I L D + I+
Sbjct: 450 SKIYAGTGAIQGGSKLMDGARSAARTIQNNLLDNSKQEAIDVLLVGSTLSSELADRARIL 509
Query: 496 ALYDPLHIYVT--RFLRQRRHEYTFEKEISIFAGTFNVNGK------LSKEKLEGWL--- 544
+ LH T R L +R EY + + GT+NVNG + K+ L WL
Sbjct: 510 LPSNMLHAPTTVLRELCKRYTEYVRPRMARVAVGTYNVNGGKHFRSIVFKDSLADWLLDC 569
Query: 545 ----------------KPENESPDLYVIGLEEIVELSPGHMLATDPYIKTFWEKKLLSEI 588
+ + D+Y IG EEIV+L+ +++A W ++L I
Sbjct: 570 HALARSKALVDVNNPSENVDHPVDIYAIGFEEIVDLNASNIMAASTDNAKLWAEELQKTI 629
Query: 589 NSYNDKKYHAVFNSQLGGLALLVFTDEENKSRIKHIEGDMKKTGFGGISSNKGAIAVHLW 648
+ ND Y + QL G+ L ++ E+ I+ + D KTG GG + NKGA A+
Sbjct: 630 SRDND--YVLLTYQQLVGVCLYIYIRPEHAPHIRDVAIDCVKTGLGGATGNKGACAIRFV 687
Query: 649 LSNTKFCFVVSHLSAGLENVEQRHNDYKSIAKHIRFSKGTRIKDHDGVIWMGDFNFRILL 708
L T CFV +H +AG V +R+ DY I + + F G +K HD V W GDFN+RI +
Sbjct: 688 LHGTSMCFVCAHFAAGQSQVAERNADYAEITRKLAFPMGRTLKSHDWVFWCGDFNYRIDM 747
Query: 709 SNDDVRQAIIDKNYHRLFEKDQLNQQMISGESFPFFDEMEITFPPTYKFNPGTDVYDTSE 768
D++++ + + + + E DQL ++ +G F F E EITF PTYK++ +D YDTSE
Sbjct: 748 EKDELKECVRNGDLSTVLEFDQLRKEQEAGNVFGEFLEGEITFDPTYKYDLFSDDYDTSE 807
Query: 769 KMRIPAWTDRILSR-----------------GEILRQELYGSAEDIVFSDHRPVYGLFTA 811
K R PAWTDR+L R G+++ YG +E + SDHRPV + A
Sbjct: 808 KQRAPAWTDRVLWRRRKALAEGDFAASAWNPGKLIH---YGRSE-LKQSDHRPVIAIIDA 863
Query: 812 KLTVIDEPKK 821
++ ID+ ++
Sbjct: 864 EIMEIDQQRR 873
>Hs14747866 [U] KOG0566 Inositol-145-triphosphate 5-phosphatase (synaptojanin)
INP51/INP52/INP53 family
Length = 1496
Score = 243 bits (620), Expect = 1e-63
Identities = 221/820 (26%), Positives = 361/820 (43%), Gaps = 144/820 (17%)
Query: 102 IEEETIYQILNINFYCIDSDKYDSMFQDLSDIGYERQLTEHPCGHLKMLISDGSFYYS-- 159
I + IY+I +FY + + + ER + LK ++S G FY+S
Sbjct: 91 IPDAEIYKITATDFYPLQEEAKEE----------ERLIA------LKKILSSGVFYFSWP 134
Query: 160 ND---FDITNSLQERGLVHRIEYTIDNQDQRYVWNYNQISEIVQLRSRIAVQERPYFDSG 216
ND FD+T Q++G D+ + + +NQ+ + + +++ +
Sbjct: 135 NDGSRFDLTVRTQKQG--------DDSSEWGNSFFWNQLLHVPLRQHQVSCCD------- 179
Query: 217 SFLVFLVRGFCQTIT------DGISSSCTLISRISTEGMNNLSEFKGIDQSGKVSNFVET 270
+L++ C +T + L+SR+S E +G++ G VSNFVET
Sbjct: 180 ----WLLKIICGVVTIRTVYASHKQAKACLVSRVSCERTGTRFHTRGVNDDGHVSNFVET 235
Query: 271 EIIVQTRRNVFSYTMTGGDIPLNWELVEGQFLHGKKPKLLSKASTVQPSFDLHFDELMSK 330
E ++ V S+ G +PL WE G + +L P+FD H L +
Sbjct: 236 EQMIYMDDGVSSFVQIRGSVPLFWEQ-PGLQVGSHHLRLHRGLEANAPAFDRHMVLLKEQ 294
Query: 331 YGVVSIVNVSKPKNDAYEAMINTYQKC--ASSKGIDLTLI--EDSTSALNRIPHRIIYLL 386
YG +VN+ + E + ++K AS D +I + A ++ LL
Sbjct: 295 YGQQVVVNLLGSRGGE-EVLNRAFKKLLWASCHAGDTPMINFDFHQFAKGGKLEKLETLL 353
Query: 387 --QQKIYEFGSFAYDMDKKIYVGKQTGVFRISAVNLFKKLNIVEKVISADVLELTINEL- 443
Q K++ + + + Q G R++ ++ + N V+ I+ +VL L + L
Sbjct: 354 RPQLKLHWEDFDVFTKGENVSPRFQKGTLRMNCLDCLDRTNTVQSFIALEVLHLQLKTLG 413
Query: 444 -EEKDISSDFWKSHDSLWKSNDFWLERL--NSKHSKNPSKYKKIYRGLFDPSAIVA---- 496
K I F +S ++W N L ++ S+ + +K K+ G S +
Sbjct: 414 LSSKPIVDRFVESFKAMWSLNGHSLSKVFTGSRALEGKAKVGKLKDGARSMSRTIQSNFF 473
Query: 497 ---------------------------LYDPLHIYVT----RFLRQRRHEYTFEKEISIF 525
L D + VT + + +R+ E+T K I I
Sbjct: 474 DGVKQEAIKLLLVGDVYGEEVADKGGMLLDSTALLVTPRILKAMTERQSEFTNFKRIRIA 533
Query: 526 AGTFNVNGK-------LSKEKLEGWL-----------KPENESP-DLYVIGLEEIVELSP 566
GT+NVNG L +L WL ++ SP D++ +G EE+VELS
Sbjct: 534 MGTWNVNGGKQFRSNVLRTAELTDWLLDSPQLSGATDSQDDSSPADIFAVGFEEMVELSA 593
Query: 567 GHMLATDPYIKTFWEKKLLSEINSYNDKKYHAVFNSQLGGLALLVFTDEENKSRIKHIEG 626
G+++ K W ++L I+ +Y + ++QL G+ L +F + I+ +
Sbjct: 594 GNIVNASTTNKKMWGEQLQKAIS--RSHRYILLTSAQLVGVCLYIFVRPYHVPFIRDVAI 651
Query: 627 DMKKTGFGGISSNKGAIAVHLWLSNTKFCFVVSHLSAGLENVEQRHNDYKSIAKHIRFSK 686
D KTG GG + NKGA+ + +T FCF+ SHL+AG V++R+ DYK I + + F
Sbjct: 652 DTVKTGMGGKAGNKGAVGIRFQFHSTSFCFICSHLTAGQSQVKERNEDYKEITQKLCFPM 711
Query: 687 GTRIKDHDGVIWMGDFNFRILLSNDDVRQAIIDKNYHRLFEKDQLNQQMISGESFPFFDE 746
G + HD V W GDFN+RI L+ ++V + +++ +L E DQL Q SG+ F F E
Sbjct: 712 GRNVFSHDYVFWCGDFNYRIDLTYEEVFYFVKRQDWKKLLEFDQLQLQKSSGKIFKDFHE 771
Query: 747 MEITFPPTYKFNPGTDVYDTSEKMRIPAWTDRIL----------SRGE--ILRQEL---- 790
I F PTYK++ G+ YDTS+K R PAWTDR+L + GE +L +L
Sbjct: 772 GAINFGPTYKYDVGSAAYDTSDKCRTPAWTDRVLWWRKKHPFDKTAGELNLLDSDLDVDT 831
Query: 791 -------------YGSAEDIVFSDHRPVYGLFTAKLTVID 817
YG AE + SDHRPV + ++ +D
Sbjct: 832 KVRHTWSPGALQYYGRAE-LQASDHRPVLAIVEVEVQEVD 870
>Hs4507335 [U] KOG0566 Inositol-145-triphosphate 5-phosphatase (synaptojanin)
INP51/INP52/INP53 family
Length = 1575
Score = 234 bits (597), Expect = 5e-61
Identities = 185/692 (26%), Positives = 305/692 (43%), Gaps = 112/692 (16%)
Query: 240 LISRISTEGMNNLSEFKGIDQSGKVSNFVETEIIVQTRRNVFSYTMTGGDIPLNWELVEG 299
LISR+S E +G + G V+NFVETE +V +V S+ G +PL WE G
Sbjct: 203 LISRLSCERAGTRFNVRGTNDDGHVANFVETEQVVYLDDSVSSFIQIRGSVPLFWEQ-PG 261
Query: 300 QFLHGKKPKLLSKASTVQPSFDLHFDELMSKYGVVSIVNVSKPK------NDAYEAMINT 353
+ + ++ P+FD HF L + YG IVN+ K + A+++ +
Sbjct: 262 LQVGSHRVRMSRGFEANAPAFDRHFRTLKNLYGRQIIVNLLGSKEGEHMLSKAFQSHLKA 321
Query: 354 YQKCASSKGIDLTLIEDSTSALNRIPHRIIYLLQQKIYEFGSFAYDMDKKIYVGKQTGVF 413
+ A + ++ + H ++ QK ++G F ++ + Q+G
Sbjct: 322 SEHAADIQMVNFDYHQMVKGGKAEKLHSVLKPQVQKFLDYGFFYFNGSEVQRC--QSGTV 379
Query: 414 RISAVNLFKKLNIVEKVISADVLELTINEL---EEKDISSDFWKSHDSLWKSNDFWLERL 470
R + ++ + N V+ + ++L + L E+ + + F + S+W N + ++
Sbjct: 380 RTNCLDCLDRTNSVQAFLGLEMLAKQLEALGLAEKPQLVTRFQEVFRSMWSVNGDSISKI 439
Query: 471 NSKHSKNPSKYK----------KIYRGLFDPSA-----IVALYDPLH---------IYVT 506
+ K K I FD S ++ L + L+ + T
Sbjct: 440 YAGTGALEGKAKLKDGARSVTRTIQNNFFDSSKQEAIDVLLLGNTLNSDLADKARALLTT 499
Query: 507 RFLR------------------QRRHEYTFEKEISIFAGTFNVNG-------KLSKEKLE 541
LR + ++Y+ K+I + GT+NVNG + L
Sbjct: 500 GSLRVSEQTLQSASSKVLKSMCENFYKYSKPKKIRVCVGTWNVNGGKQFRSIAFKNQTLT 559
Query: 542 GWL-------------KPENESPDLYVIGLEEIVELSPGHMLATDPYIKTFWEKKLLSEI 588
WL ++ D++ IG EE+VEL+ G++++ + W +L I
Sbjct: 560 DWLLDAPKLAGIQEFQDKRSKPTDIFAIGFEEMVELNAGNIVSASTTNQKLWAVELQKTI 619
Query: 589 NSYNDKKYHAVFNSQLGGLALLVFTDEENKSRIKHIEGDMKKTGFGGISSNKGAIAVHLW 648
+ D KY + + QL G+ L VF ++ I+ + D KTG GG + NKGA+A+ +
Sbjct: 620 S--RDNKYVLLASEQLVGVCLFVFIRPQHAPFIRDVAVDTVKTGMGGATGNKGAVAIRML 677
Query: 649 LSNTKFCFVVSHLSAGLENVEQRHNDYKSIAKHIRFSKGTRIKDHDGVIWMGDFNFRILL 708
T CFV SH +AG V++R+ D+ IA+ + F G + HD V W GDFN+RI L
Sbjct: 678 FHTTSLCFVCSHFAAGQSQVKERNEDFIEIARKLSFPMGRMLFSHDYVFWCGDFNYRIDL 737
Query: 709 SNDDVRQAIIDKNYHRLFEKDQLNQQMISGESFPFFDEMEITFPPTYKFNPGTDVYDTSE 768
N++V++ I +N+ L DQL Q +G+ F F E ++TF PTYK++ +D YDTSE
Sbjct: 738 PNEEVKELIRQQNWDSLIAGDQLINQKNAGQVFRGFLEGKVTFAPTYKYDLFSDDYDTSE 797
Query: 769 KMRIPAWTDRILSR--------------------------------GEILRQELYGSAED 796
K R PAWTDR+L R G +L YG AE
Sbjct: 798 KCRTPAWTDRVLWRRRKWPFDRSAEDLDLLNASFQDESKILYTWTPGTLLH---YGRAE- 853
Query: 797 IVFSDHRPVYGLFTAKLTVIDEPKKAKLVASI 828
+ SDHRPV L + ++ ++ + +
Sbjct: 854 LKTSDHRPVVALIDIDIFEVEAEERQNIYKEV 885
>Hs22045277 [U] KOG0565 Inositol polyphosphate 5-phosphatase and related
proteins
Length = 652
Score = 207 bits (527), Expect = 6e-53
Identities = 128/384 (33%), Positives = 203/384 (52%), Gaps = 26/384 (6%)
Query: 468 ERLNSKHSKNPSKYKKIYRGLFDPSAIVALYDPLHIY-----------VTRFLRQRRHEY 516
E L + +K+ S+ + R S+ + + D HI V L Q+ +Y
Sbjct: 205 ESLQPRQNKSKSEITDMVR-----SSTITVSDKAHILSMQKFGLRDTIVKSHLLQKEEDY 259
Query: 517 TFEKEISIFAGTFNVNGKLSKEKLEGWLKPENESPDLYVIGLEEIVELSPGHMLATDPYI 576
T+ + FAGT+NVNG+ KE L WL ++PD+Y +G +E+ +LS D
Sbjct: 260 TYIQNFRFFAGTYNVNGQSPKECLRLWLSNGIQAPDVYCVGFQEL-DLSKEAFFFHDTPK 318
Query: 577 KTFWEKKLLSEINSYNDKKYHAVFNSQLGGLALLVFTDEENKSRIKHIEGDMKKTGFGGI 636
+ W K + ++ D KY V +L G+ LL++ +E+ + I +E + TG G
Sbjct: 319 EEEWFKAVSEGLHP--DAKYAKVKLIRLVGIMLLLYVKQEHAAYISEVEAETVGTGIMGR 376
Query: 637 SSNKGAIAVHLWLSNTKFCFVVSHLSAGLENVEQRHNDYKSIAKHIRFSKGT------RI 690
NKG +A+ NT C V SHL+A +E E+R+ DYK I ++F + I
Sbjct: 377 MGNKGGVAIRFQFHNTSICVVNSHLAAHIEEYERRNQDYKDICSRMQFCQPDPSLPPLTI 436
Query: 691 KDHDGVIWMGDFNFRIL-LSNDDVRQAIIDKNYHRLFEKDQLNQQMISGESFPFFDEMEI 749
+HD ++W+GD N+RI L + V++ I +K++ L+ DQL Q+ + F F E E+
Sbjct: 437 SNHDVILWLGDLNYRIEELDVEKVKKLIEEKDFQMLYAYDQLKIQVAAKTVFEGFTEGEL 496
Query: 750 TFPPTYKFNPGTDVYDTSEKMRIPAWTDRILSRGEILRQELYGSAEDIVFSDHRPVYGLF 809
TF PTYK++ G+D +DTSEK R PAW DRIL +G+ + Q Y S + SDH+PV +F
Sbjct: 497 TFQPTYKYDTGSDDWDTSEKCRAPAWCDRILWKGKNITQLSYQSHMALKTSDHKPVSSVF 556
Query: 810 TAKLTVIDEPKKAKLVASIKDSIN 833
+ V+++ K + I S++
Sbjct: 557 DIGVRVVNDELYRKTLEEIVRSLD 580
>7290234 [U] KOG0565 Inositol polyphosphate 5-phosphatase and related
proteins
Length = 850
Score = 202 bits (514), Expect = 2e-51
Identities = 117/335 (34%), Positives = 177/335 (51%), Gaps = 8/335 (2%)
Query: 505 VTRFLRQRRHEYTFEKEISIFAGTFNVNGKL---SKEKLEGWLKPENESPDLYVIGLEEI 561
V + L++R EY K+I I+ T+NVN K S L WL + PD+Y IGL+E+
Sbjct: 168 VKQELKKRESEYIVYKDIIIYCATWNVNNKTCSDSNNPLRAWLACSEKPPDIYAIGLQEL 227
Query: 562 VELSPGHMLATDPY-IKTFWEKKLLSEINSYNDKKYHAVFNSQLGGLALLVFTDEENKSR 620
+ + +T I+ W K++ ++ D +Y + + +L L V ++ +
Sbjct: 228 DTPTKAMLNSTQVQAIEKQWIDKMMDSVHP--DVEYEILMSHRLVATMLTVIVRKQLRQH 285
Query: 621 IKHIEGDMKKTGFGGISSNKGAIAVHLWLSNTKFCFVVSHLSAGLENVEQRHNDYKSIAK 680
I G NKG +A+ L L+ CFV SHL+A + VE+R+ DY +I +
Sbjct: 286 IIRCRPKSVARGIFNTLGNKGGVAISLQLNEGNICFVNSHLAAHMGYVEERNQDYNAIVE 345
Query: 681 HIRFSKGTRIKDHDGVIWMGDFNFRILLSNDDVRQAIID--KNYHRLFEKDQLNQQMISG 738
IRF G I DHD + W+GD N+RI R + + Y L + DQL Q+M G
Sbjct: 346 GIRFDDGRTISDHDHIFWVGDLNYRIQEPPGQQRPGPLSDAQTYELLLQYDQLRQEMRRG 405
Query: 739 ESFPFFDEMEITFPPTYKFNPGTDVYDTSEKMRIPAWTDRILSRGEILRQELYGSAEDIV 798
+ F + E EI F PTYK++PGTD YD+SEK R PA+ DR+L +G + Q Y S +I
Sbjct: 406 KCFEGYTEGEIKFRPTYKYDPGTDNYDSSEKQRAPAYCDRVLWKGTRIEQLAYNSIMEIR 465
Query: 799 FSDHRPVYGLFTAKLTVIDEPKKAKLVASIKDSIN 833
SDH+PVY +F K+ DE K ++ + +++
Sbjct: 466 QSDHKPVYAVFQVKVKTRDEVKYKRVQEEVLKAVD 500
>Hs13325072 [U] KOG0565 Inositol polyphosphate 5-phosphatase and related
proteins
Length = 901
Score = 196 bits (497), Expect = 2e-49
Identities = 127/365 (34%), Positives = 187/365 (50%), Gaps = 13/365 (3%)
Query: 467 LERLNSKHSKNPSKYKKIYRGLFDPSAIVALYDPLHIYVTRFLRQRRHEYTFEKEISIFA 526
L R +K K R LF P+ + L + L +R EY + F
Sbjct: 188 LPREKEASNKEQPKVTNTMRKLFVPNTQSGQREGL---IKHILAKREKEYVNIQTFRFFV 244
Query: 527 GTFNVNGKLSKEKLEGWLKPENESPDLYVIGLEEIVELSPGHMLATDPYIKTFWEKKLLS 586
GT+NVNG+ LE WL + PD+Y IG +E+ +LS + + W +
Sbjct: 245 GTWNVNGQSPDSGLEPWLNCDPNPPDIYCIGFQEL-DLSTEAFFYFESVKEQEWSMAV-- 301
Query: 587 EINSYNDKKYHAVFNSQLGGLALLVFTDEENKSRIKHIEGDMKKTGFGGISSNKGAIAVH 646
E ++ KY V +L G+ LL+F ++ I+ I + TG G NKG +AV
Sbjct: 302 ERGLHSKAKYKKVQLVRLVGMMLLIFARKDQCRYIRDIATETVGTGIMGKMGNKGGVAVR 361
Query: 647 LWLSNTKFCFVVSHLSAGLENVEQRHNDYKSIAKHIRFSKGTR------IKDHDGVIWMG 700
NT FC V SHL+A +E+ E+R+ DYK I + F + I H+ VIW+G
Sbjct: 362 FVFHNTTFCIVNSHLAAHVEDFERRNQDYKDICARMSFVVPNQTLPQLNIMKHEVVIWLG 421
Query: 701 DFNFRILLSN-DDVRQAIIDKNYHRLFEKDQLNQQMISGESFPFFDEMEITFPPTYKFNP 759
D N+R+ + + ++V+ I K+ RL + DQLN Q ++F F+E EI F PTYK++
Sbjct: 422 DLNYRLCMPDANEVKSLINKKDLQRLLKFDQLNIQRTQKKAFVDFNEGEIKFIPTYKYDS 481
Query: 760 GTDVYDTSEKMRIPAWTDRILSRGEILRQELYGSAEDIVFSDHRPVYGLFTAKLTVIDEP 819
TD +D+S K R+PAW DRIL RG + Q Y S ++ SDH+PV LF + V+DE
Sbjct: 482 KTDRWDSSGKCRVPAWCDRILWRGTNVNQLNYRSHMELKTSDHKPVSALFHIGVKVVDER 541
Query: 820 KKAKL 824
+ K+
Sbjct: 542 RYRKV 546
>Hs13325070 [U] KOG0565 Inositol polyphosphate 5-phosphatase and related
proteins
Length = 893
Score = 196 bits (497), Expect = 2e-49
Identities = 127/365 (34%), Positives = 187/365 (50%), Gaps = 13/365 (3%)
Query: 467 LERLNSKHSKNPSKYKKIYRGLFDPSAIVALYDPLHIYVTRFLRQRRHEYTFEKEISIFA 526
L R +K K R LF P+ + L + L +R EY + F
Sbjct: 188 LPREKEASNKEQPKVTNTMRKLFVPNTQSGQREGL---IKHILAKREKEYVNIQTFRFFV 244
Query: 527 GTFNVNGKLSKEKLEGWLKPENESPDLYVIGLEEIVELSPGHMLATDPYIKTFWEKKLLS 586
GT+NVNG+ LE WL + PD+Y IG +E+ +LS + + W +
Sbjct: 245 GTWNVNGQSPDSGLEPWLNCDPNPPDIYCIGFQEL-DLSTEAFFYFESVKEQEWSMAV-- 301
Query: 587 EINSYNDKKYHAVFNSQLGGLALLVFTDEENKSRIKHIEGDMKKTGFGGISSNKGAIAVH 646
E ++ KY V +L G+ LL+F ++ I+ I + TG G NKG +AV
Sbjct: 302 ERGLHSKAKYKKVQLVRLVGMMLLIFARKDQCRYIRDIATETVGTGIMGKMGNKGGVAVR 361
Query: 647 LWLSNTKFCFVVSHLSAGLENVEQRHNDYKSIAKHIRFSKGTR------IKDHDGVIWMG 700
NT FC V SHL+A +E+ E+R+ DYK I + F + I H+ VIW+G
Sbjct: 362 FVFHNTTFCIVNSHLAAHVEDFERRNQDYKDICARMSFVVPNQTLPQLNIMKHEVVIWLG 421
Query: 701 DFNFRILLSN-DDVRQAIIDKNYHRLFEKDQLNQQMISGESFPFFDEMEITFPPTYKFNP 759
D N+R+ + + ++V+ I K+ RL + DQLN Q ++F F+E EI F PTYK++
Sbjct: 422 DLNYRLCMPDANEVKSLINKKDLQRLLKFDQLNIQRTQKKAFVDFNEGEIKFIPTYKYDS 481
Query: 760 GTDVYDTSEKMRIPAWTDRILSRGEILRQELYGSAEDIVFSDHRPVYGLFTAKLTVIDEP 819
TD +D+S K R+PAW DRIL RG + Q Y S ++ SDH+PV LF + V+DE
Sbjct: 482 KTDRWDSSGKCRVPAWCDRILWRGTNVNQLNYRSHMELKTSDHKPVSALFHIGVKVVDER 541
Query: 820 KKAKL 824
+ K+
Sbjct: 542 RYRKV 546
>At2g01900 [U] KOG0565 Inositol polyphosphate 5-phosphatase and related
proteins
Length = 417
Score = 157 bits (398), Expect = 6e-38
Identities = 105/334 (31%), Positives = 166/334 (49%), Gaps = 35/334 (10%)
Query: 524 IFAGTFNVNGKLSKEKL--EGWLKPENESPDLYVIGLEEIVELSPGHMLATDPY-IKTFW 580
+F T+NV G + + L E L+ D+YV+G +E+V L ++L +D + T W
Sbjct: 60 VFVSTWNVGGIVPDDGLDMEDLLETHKTPCDIYVLGFQEVVPLRASNVLGSDNNKVSTKW 119
Query: 581 EKKL---------------LSEINSYN--DKKYHAVFNSQLGGLALLVFTDEENKSRIKH 623
+ LSE N + + + + Q+ G+ + V+ + I++
Sbjct: 120 NSLIRDALNKRARPHRDEDLSESKGINGISQDFRCIISKQMVGILITVWVRGDLWPYIRY 179
Query: 624 IEGDMKKTGFGGISSNKGAIAVHLWLSNTKFCFVVSHLSAGLENVE--QRHNDYKSIAKH 681
G G NKG+++V L T FCFV SHL++G + + QR++D I
Sbjct: 180 PSVSCVGCGIMGCLGNKGSVSVRFQLHETTFCFVCSHLASGGRDRDERQRNSDVNEILAR 239
Query: 682 IRFSKGT------RIKDHDGVIWMGDFNFRILLSNDDVRQAIIDKNYHRLFEKDQLNQQM 735
F +G+ +I DHD VI++GD N+RI L + R + K ++ L E DQL ++
Sbjct: 240 SSFPRGSSLDLPKKILDHDRVIFLGDLNYRISLPEEKTRLLVESKKWNILLENDQLRMEI 299
Query: 736 ISGESFPFFDEMEITFPPTYKFNPGTDV------YDTSEKMRIPAWTDRILSRGEILRQE 789
++G+ F + E + F PTYK+ P +D+ Y EK R PAW DRI+ G L+Q
Sbjct: 300 MNGQIFRGWQEGIVKFAPTYKYVPNSDLYYGCITYKKDEKKRAPAWCDRIIWYGNGLKQH 359
Query: 790 LYGSAEDIVFSDHRPVYGLFTAKLTVIDEPKKAK 823
Y E + SDHRPV +FT ++TV KK +
Sbjct: 360 EYTRGETKI-SDHRPVKAIFTTEITVTRRGKKIR 392
>CE17405 [U] KOG0565 Inositol polyphosphate 5-phosphatase and related
proteins
Length = 753
Score = 153 bits (386), Expect = 1e-36
Identities = 106/345 (30%), Positives = 175/345 (50%), Gaps = 34/345 (9%)
Query: 505 VTRFLRQRRHEYTFEKEISIFAGTFNVNGKLSKEKLEGWL--KPENESPDLYVIGLEEIV 562
V +R+ H++ +++ I TFNVNG+ W KPE+ + + Y +GL+E+
Sbjct: 78 VDEVMREWMHKFCTFQDVKICVSTFNVNGRSPLSVFPTWFSQKPEDIA-EFYAVGLQEM- 135
Query: 563 ELSPGHMLATDPYIKTFWEKKLLSEINSYNDKKYHAVFNSQLGGLALLVFTDEENKSRIK 622
+LS G + + W + + +++ V + +L G+ ++VF +K R+
Sbjct: 136 DLSVGTYIIDNTKKMEGWVDAIHCSLPG-GRTQFNVVGSMRLVGIFVIVFQAVNSKVRVS 194
Query: 623 HIEGDMKKTGFGGISS---NKGAIAVHLWLSNTKFCFVVSHLSAGLENVEQRHNDYKSIA 679
+ TG + + NKG AV + +++T CFV +H +AG +E+R+ D++ I
Sbjct: 195 DVNVKYVATGISVLVNKLGNKGGTAVSMKMNDTWVCFVNAHFAAGNNELERRNQDFRDIY 254
Query: 680 KHIRF-----SKGTR----------IKDHDGVIWMGDFNFRIL-----LSNDDVRQAIID 719
+ F +G R + DHD V W GD N+R+ +SND+VR+
Sbjct: 255 NDMVFYPRSQQEGLRDRPLEVPIMCLYDHDVVFWFGDLNYRLNTDMYGISNDEVRRIASS 314
Query: 720 KNYHRLFEKDQLNQQMISGESFPFFDEME-ITFPPTYKFNPGTDVYDTSEKMRIPAWTDR 778
+ L + QL +QM G F F+E + F PTYK++ GT+ +DTSEK R+PAWTDR
Sbjct: 315 DKFADLLQHCQLREQMARGTVFKDFEEPSTLPFRPTYKYDCGTNTWDTSEKGRVPAWTDR 374
Query: 779 ILSRGEILRQELYG-----SAEDIVFSDHRPVYGLFTAKLTVIDE 818
IL+ + + L S + I SDH+PV +F K+ I+E
Sbjct: 375 ILTFKKYPQVGLESIRPMVSIDTITISDHKPVRAMFNLKVKKINE 419
>At2g37440 [U] KOG0565 Inositol polyphosphate 5-phosphatase and related
proteins
Length = 401
Score = 153 bits (386), Expect = 1e-36
Identities = 111/354 (31%), Positives = 176/354 (49%), Gaps = 57/354 (16%)
Query: 522 ISIFAGTFNVNGKLSKEKLE--GWLKPENESPDLYVIG-------------------LEE 560
I +F GT+NV GK E L+ WLK ++ D+YV+G +E
Sbjct: 2 IRMFVGTWNVGGKSPHEGLDLKDWLKSPADA-DIYVLGYAYNHINWFYRTFNILFLEFQE 60
Query: 561 IVELSPGHML-ATDPYIKTFWEKKLLSEINSYND-------------------KKYHAVF 600
IV L+ G++L A D W + +N+ N+ + Y
Sbjct: 61 IVPLNAGNVLGAEDNGPAAKWLSLIREALNNTNNLSFSGLSDDTPIPCNSTPPRGYSLAA 120
Query: 601 NSQLGGLALLVFTDEENKSRIKHIEGDMKKTGFGGISSNKGAIAVHLWLSNTKFCFVVSH 660
+ Q+ G+ L V+ ++ + RI +++ G G NKG++++ + L T CFV +H
Sbjct: 121 SKQMVGIFLCVWVRDDLRKRITNLKVSCVGRGIMGYLGNKGSVSISMSLHETSLCFVCTH 180
Query: 661 LSAG-LENVEQRHN-DYKSIAKHIRFSKGTR------IKDHDGVIWMGDFNFRILLSNDD 712
L++G E E R N D I K RFS+ ++ I DHD VIW+GD N+R L ++ D
Sbjct: 181 LTSGEKEGDELRRNLDVTEIFKRTRFSRSSKDSRPETIMDHDKVIWLGDLNYR-LRASSD 239
Query: 713 VRQAIIDKNYHRLFEKDQLNQQMISGESFPFFDEMEITFPPTYKFNPGTDVY-----DTS 767
+ + + + ++ L EKDQL + +G F ++E +I F PTYK+ +D Y +
Sbjct: 240 LHEQLRNHDWESLLEKDQLKIEQRAGRIFKGWEEGKIYFAPTYKYRINSDNYVVQTEKSK 299
Query: 768 EKMRIPAWTDRILSRGEILRQELYGSAEDIVFSDHRPVYGLFTAKLTVIDEPKK 821
EK R PAW DRIL +G+ ++Q Y E FSDHRPV LF+ + + ++ +
Sbjct: 300 EKRRTPAWCDRILWKGDGMKQLWYVRGES-KFSDHRPVQSLFSVHIDLKNQSNR 352
>7302845 [U] KOG0565 Inositol polyphosphate 5-phosphatase and related
proteins
Length = 357
Score = 152 bits (384), Expect = 2e-36
Identities = 98/287 (34%), Positives = 149/287 (51%), Gaps = 25/287 (8%)
Query: 546 PENESPDLYVIGLEEIVELSPGHMLATDPYIKTFWEKKLLSEI-NSYNDKKYHAVFNSQL 604
P+N+ PD+YVIG +E+ T +K F + + +I +S +D ++ V + QL
Sbjct: 42 PDNQLPDIYVIGFQEVS--------TTPQVLKIFNDDPWVLKIADSLSDHQFVKVDSKQL 93
Query: 605 GGLALLVFTDEENKSRIKHIEGDMKKTGFGGISSNKGAIAVHLWLSNTKFCFVVSHLSAG 664
G+ + +F ++ +K IE + +TG GG+ NKGA+++ L L T FV SHL+A
Sbjct: 94 QGILITMFAQHKHIPHMKEIETEATRTGLGGLWGNKGAVSIRLSLYGTGVAFVCSHLAAH 153
Query: 665 LENVEQRHNDYKSIAKHIRFSKG--TRIKDHDGVIWMGDFNFRIL--LSNDDVRQAIIDK 720
E +++R DY I + +++ RI DHD V W GD NFR+ +S DVR + ++
Sbjct: 154 DEKLKERIEDYHQIVDNHKYNAQGYRRIFDHDFVFWFGDLNFRLSGDMSAWDVRTDVENQ 213
Query: 721 NYHRLFEKDQLNQQMISGESFPFFDEMEITFPPTYKFNPGTDVYDTSEKMRIPAWTDRIL 780
Y L + DQLN G +F +E + F PT+KF GT+ Y+ R PAW DRIL
Sbjct: 214 RYADLLKLDQLNLLREKGNAFSLLEEQQPNFAPTFKFVEGTNDYNLK---RRPAWCDRIL 270
Query: 781 SRGE---------ILRQELYGSAEDIVFSDHRPVYGLFTAKLTVIDE 818
R + Q Y S D SDH+PV F K+ ++
Sbjct: 271 HRVQSNIYPGITLSANQLSYQSHMDYTLSDHKPVSATFNYKVEAANQ 317
>At2g32010 [U] KOG0565 Inositol polyphosphate 5-phosphatase and related
proteins
Length = 501
Score = 150 bits (379), Expect = 9e-36
Identities = 85/230 (36%), Positives = 128/230 (54%), Gaps = 8/230 (3%)
Query: 591 YNDKKYHAVFNSQLGGLALLVFTDEENKSRIKHIEGDMKKTGFGGISSNKGAIAVHLWLS 650
+N +Y V + Q+ G+ L ++ E + +K+++ G G NKG+I++ + L
Sbjct: 237 WNSSQYCLVASKQMVGIFLTIWVKSELREHVKNMKVSCVGRGLMGYLGNKGSISISMLLH 296
Query: 651 NTKFCFVVSHLSAGLENVEQ--RHNDYKSIAKHIRFSKGTRIKDHDGVIWMGDFNFRILL 708
T FCFV +HL++G + ++ R++D I K RF + D + VIW+GD N+RI L
Sbjct: 297 QTSFCFVCTHLTSGQKEGDELRRNSDVMEILKKTRFPRVQSSADENRVIWLGDLNYRIAL 356
Query: 709 SNDDVRQAIIDKNYHRLFEKDQLNQQMISGESFPFFDEMEITFPPTYKFNPGTDVY---- 764
S + + +N+ L E DQL + G F ++E +I FPPTYK++ +D Y
Sbjct: 357 SYRSAKALVEMQNWRALLENDQLRIEQKRGHVFKGWNEGKIYFPPTYKYSNNSDRYAGGD 416
Query: 765 -DTSEKMRIPAWTDRILSRGEILRQELYGSAEDIVFSDHRPVYGLFTAKL 813
EK R PAW DRIL GE L Q Y E FSDHRPVYG+F+A++
Sbjct: 417 LHPKEKRRTPAWCDRILWHGEGLHQLSYVRGES-RFSDHRPVYGIFSAEV 465
>At1g05470 [U] KOG0565 Inositol polyphosphate 5-phosphatase and related
proteins
Length = 585
Score = 146 bits (368), Expect = 2e-34
Identities = 87/239 (36%), Positives = 128/239 (53%), Gaps = 17/239 (7%)
Query: 591 YNDKKYHAVFNSQLGGLALLVFTDEENKSRIKHIEGDMKKTGFGGISSNKGAIAVHLWLS 650
+N +Y V + Q+ G+ L ++ E + +K+++ G G NKG+I++ + L
Sbjct: 312 WNSSQYCLVASKQMVGVFLTIWVKSELREHVKNMKVSCVGRGLMGYLGNKGSISISMLLH 371
Query: 651 NTKFCFVVSHLSAGLENVEQ--RHNDYKSIAKHIRFSK---------GTRIKDHDGVIWM 699
T FCFV +HL++G + ++ R++D I K RF + I HD VIW+
Sbjct: 372 QTSFCFVCTHLTSGQKEGDELKRNSDVMEILKKTRFPRVKSSEEEKSPENILQHDRVIWL 431
Query: 700 GDFNFRILLSNDDVRQAIIDKNYHRLFEKDQLNQQMISGESFPFFDEMEITFPPTYKFNP 759
GD N+RI LS + + +N+ L E DQL + G F ++E +I FPPTYK++
Sbjct: 432 GDLNYRIALSYRSAKALVEMQNWRALLENDQLRIEQKRGHVFKGWNEGKIYFPPTYKYSR 491
Query: 760 GTDVYD-----TSEKMRIPAWTDRILSRGEILRQELYGSAEDIVFSDHRPVYGLFTAKL 813
+D Y EK R PAW DRIL GE L Q Y E FSDHRPVYG+F A++
Sbjct: 492 NSDRYSGDDLHPKEKRRTPAWCDRILWFGEGLHQLSYVRGES-RFSDHRPVYGIFCAEV 549
>7293245 [U] KOG0565 Inositol polyphosphate 5-phosphatase and related
proteins
Length = 508
Score = 144 bits (363), Expect = 6e-34
Identities = 97/279 (34%), Positives = 141/279 (49%), Gaps = 24/279 (8%)
Query: 551 PDLYVIGLEEIVELSPGHMLATDPYIKTFWEKKLLSEINSYNDKKYHAVFNSQLGGLALL 610
PD+Y +GL+E+ +L + + W K + +Y+ Y AV Q+ GL L
Sbjct: 73 PDIYALGLQEVNAQPQQQVLGL--FKEDPWTHKAKELLRNYD---YVAVKTEQMQGLLLS 127
Query: 611 VFTDEENKSRIKHIEGDMKKTGFGGISSNKGAIAVHLWLSNTKFCFVVSHLSAGLENVEQ 670
+F ++ ++ IE + +TGFGGI NKGA++V L FVV+HL+A +++
Sbjct: 128 MFVRRQHVEHLQDIEAEFTRTGFGGIWGNKGAVSVRFTLYGCGLAFVVAHLTAHDHMMDE 187
Query: 671 RHNDYKSIAK--HIRFSKGTRIKDHDGVIWMGDFNFRILLSND--DVRQAIIDKNYHR-L 725
R DYK I + H + I DHD V W GD NFR+ S+ +VR+ + D++ H L
Sbjct: 188 RIEDYKQILENHHYHVKRYREIYDHDYVFWFGDLNFRLQGSDSSTEVRELVRDESQHEAL 247
Query: 726 FEKDQLNQQMISGE-SFPFFDEMEITFPPTYKFNPGTDVYDTSEKMRIPAWTDRILSRGE 784
++DQL Q + +F E FPPT+KF GT YD R PAWTDRI+ +
Sbjct: 248 IQRDQLYQVREKSQLAFQVLQERLPAFPPTFKFREGTSEYDLK---RRPAWTDRIMYAVQ 304
Query: 785 ILRQE----------LYGSAEDIVFSDHRPVYGLFTAKL 813
L ++ Y S SDH+PV FT KL
Sbjct: 305 PLNRQPGMQLSIEQCSYKSHPLYTISDHKPVTSDFTIKL 343
>SPAC9G1.10c [U] KOG0565 Inositol polyphosphate 5-phosphatase and related proteins
Length = 1191
Score = 143 bits (361), Expect = 1e-33
Identities = 111/375 (29%), Positives = 175/375 (46%), Gaps = 51/375 (13%)
Query: 492 SAIVALYDPLHI--YVTRFLRQRRHEYTFEKEISIFAGTFNVNGK----LSKEKLEGWLK 545
S++V +D L + ++ +R R EY+ ++SI ++N L + + +
Sbjct: 757 SSVVKFWDGLMMGDWLATEMRSRFPEYSNFTDVSILICSWNAGASKPSDLDSDTIGASMI 816
Query: 546 P----ENESPDLYVIGLEEIVELSPGHMLATDPYIKT-----------------FWEKKL 584
P +N PD+ V G +E+V+L + A K+ W +KL
Sbjct: 817 PMMIRDNGYPDIVVFGFQELVDLENKRLTARSILSKSSSKGGSSNSANISSQYRLWREKL 876
Query: 585 LSEIN--SYNDKKYHAVFNSQLGGLALLVFTDEENKSRIKHIEGDMKKTGFGGISSNKGA 642
SE+ S ND Y + L GL VF + +S+I+ ++ KTG GG+ NKGA
Sbjct: 877 ESEMMRVSSNDD-YQVLVCENLVGLFSCVFVKNKLQSKIRMLQSTTVKTGLGGLHGNKGA 935
Query: 643 IAVHLWLSNTKFCFVVSHLSAGLENVEQRHNDYKSIAKH----------------IRFSK 686
I V + +T +C V HL+AG N R+ND +I + +
Sbjct: 936 IVVRFLVDDTSYCIVNCHLAAGQSNKAARNNDLATILDNASLFPENDETDQLNTFVGGGD 995
Query: 687 GTRIKDHDGVIWMGDFNFRILLSNDDVRQAIIDKNYHRLFEKDQL--NQQMISGESFPFF 744
G+ I DH+ + GD N+RI I + L + DQL ++ +G F
Sbjct: 996 GSLIMDHEVCVLHGDLNYRINTLRPKALDLIKKNDIKTLLQSDQLLVERKRNAGFRLRTF 1055
Query: 745 DEMEITFPPTYKFNPGTDVYDTSEKMRIPAWTDRILSRG--EILRQELYGSAEDIVFSDH 802
E EITF PTYK++ ++ YD+SEK R+PAW DRI RG + + E Y + ++ SDH
Sbjct: 1056 TEPEITFAPTYKYDVHSEQYDSSEKKRVPAWCDRICYRGSPDYISAENY-TRYELKASDH 1114
Query: 803 RPVYGLFTAKLTVID 817
RPV L +K +++
Sbjct: 1115 RPVSALIHSKAKMVN 1129
>At5g65090 [U] KOG0565 Inositol polyphosphate 5-phosphatase and related
proteins
Length = 569
Score = 140 bits (353), Expect = 9e-33
Identities = 90/246 (36%), Positives = 128/246 (51%), Gaps = 27/246 (10%)
Query: 596 YHAVFNSQLGGLALLVFTDEENKSRIKHIEGDMKKTGFGGISSNKGAIAVHLWLSNTKFC 655
Y + + Q+ GL L V+ E I H+ D G G NKG IA+ + L T FC
Sbjct: 292 YRLIASKQMVGLFLSVWARRELIPHISHLRLDSVGRGIMGRLGNKGCIAISMSLHQTSFC 351
Query: 656 FVVSHLSAGLENVEQ--RHNDYKSIAKHIRFSKGT---------RIKDHDGVIWMGDFNF 704
FV SHL++G + ++ R+ D I KH +F K T RI DHD V+W+GD N+
Sbjct: 352 FVCSHLASGEKEGDELRRNADVAEILKHTQFPKLTKNPNCHAPERIIDHDRVLWLGDLNY 411
Query: 705 RILLSNDDVRQAIIDKNYHRLFEKDQLNQQMISGESFPFFDEMEITFPPTYKFNPGTDVY 764
R+ L+ ++ R + D ++ L E+DQLN + +G F F E +I F PTYK++ +D Y
Sbjct: 412 RVALTYEETRVLLEDNDWDTLLERDQLNMERGAGRVFSGFQEGQIFFAPTYKYSQNSDAY 471
Query: 765 -----DTSEKMRIPA------WT----DRILSRGEILRQELYGSAEDIVFSDHRPVYGLF 809
+ +K R PA W DRIL +GE + Q Y E FSDHRPV +F
Sbjct: 472 AGEMTKSKKKRRTPACVIVWIWNVCRCDRILWKGEGIEQLSYIRGES-RFSDHRPVCAIF 530
Query: 810 TAKLTV 815
++ V
Sbjct: 531 AVEVDV 536
>At5g04980 [U] KOG0565 Inositol polyphosphate 5-phosphatase and related
proteins
Length = 366
Score = 139 bits (350), Expect = 2e-32
Identities = 96/253 (37%), Positives = 133/253 (51%), Gaps = 20/253 (7%)
Query: 583 KLLSEINSYNDKKYHAVFNSQLGGLALLVFTDEENKSRIKHIEGDMKKTGFGGISSNKGA 642
K+ S +++ KY V + Q+ G+ L V+ +E + H+ G G NKG
Sbjct: 108 KVASLVSNQMTMKYGLVASKQMVGIFLTVWMRKELIQHVSHLRISSVTRGIMGCLGNKGC 167
Query: 643 IAVHLWLSNTKFCFVVSHLSAG-LENVEQRHN-DYKSIAKHIRFSK---------GTRIK 691
IAV L L T FCF+ SHL++G E E+R N D I K+ F + RI
Sbjct: 168 IAVSLQLYKTSFCFICSHLASGEREGDERRRNLDVIEILKNTSFPRICRTSFTRVPDRIT 227
Query: 692 DHDGVIWMGDFNFRILLSNDDVRQAIIDKN-YHRLFEKDQLNQQMISGESFPFFDEMEIT 750
HD VIW+GD N+RI LS + + ++DKN + L KDQL + +G F + E +I
Sbjct: 228 KHDRVIWLGDLNYRIALSYSETK-TLLDKNAWDTLLNKDQLKIERDAGRVFKGWHEGKIF 286
Query: 751 FPPTYKFNPGTDVY--DTSE----KMRIPAWTDRILSRGEILRQELYGSAEDIVFSDHRP 804
F PTYK++ +D Y DTS+ K R PAW DRIL G+ +RQ Y E FSDHRP
Sbjct: 287 FAPTYKYSYNSDAYAGDTSKEKKNKRRTPAWCDRILWHGDGIRQLSYVRGES-RFSDHRP 345
Query: 805 VYGLFTAKLTVID 817
V +F + V +
Sbjct: 346 VCSVFVVDVEVCE 358
>At2g43900 [U] KOG0565 Inositol polyphosphate 5-phosphatase and related
proteins
Length = 1305
Score = 138 bits (347), Expect = 5e-32
Identities = 105/381 (27%), Positives = 168/381 (43%), Gaps = 68/381 (17%)
Query: 500 PLHIYVTRFLRQRRHEYTFEKEISIFAGTFNVN-GKLSKEKLEGWLKPENESPDLYVIGL 558
PL + L ++ Y + I G++NV GK S + L WL + V+GL
Sbjct: 554 PLDGIIRSELAEKERTYAQTDSVRILTGSWNVGQGKASHDALMSWLGSVASDVGILVVGL 613
Query: 559 EEIVELSPGHMLAT----------DPYIKTFWEKKLLSEINSYNDKK--YHAVFNSQLGG 606
+E VE+ G + + I +W + I D+K + + + QL G
Sbjct: 614 QE-VEMGAGFLAMSAAKESVGGNEGSTIGQYW----IDTIGKTLDEKAVFERMGSRQLAG 668
Query: 607 LALLVFTDEENKSRIKHIEGDMKKTGFGGISSNKGAIAVHLWLSNTKFCFVVSHLSAGLE 666
L + ++ + ++ + I+ GFG NKG + + + + + CF+ HL+A LE
Sbjct: 669 LLISLWVRKNLRTHVGDIDVAAVPCGFGRAIGNKGGVGLRIRVFDRIMCFINCHLAAHLE 728
Query: 667 NVEQRHNDYKSIAKHIRFSKGTR--------------------------------IKDHD 694
V +R+ D+ I K + F++ + + + D
Sbjct: 729 AVNRRNADFDHIYKTMSFTRSSNAHNAPAAGVSTGSHTTKSANNANVNTEETKQDLAEAD 788
Query: 695 GVIWMGDFNFRIL-LSNDDVRQAIIDKNYHRLFEKDQLNQQMISGESFPFFDEMEITFPP 753
V++ GDFN+R+ +S D+ R + +++ L EKDQL +M +G F E ITFPP
Sbjct: 789 MVVFFGDFNYRLFGISYDEARDFVSQRSFDWLREKDQLRAEMKAGRVFQGMREAIITFPP 848
Query: 754 TYKF---NPGTDVYDTSEKMRIPAWTDRILSRGEILRQE--------------LYGSAED 796
TYKF PG YD+ EK RIPAW DR++ R E LY + D
Sbjct: 849 TYKFERHRPGLGGYDSGEKKRIPAWCDRVIFRDTRTSPESECSLDCPVVASIMLYDACMD 908
Query: 797 IVFSDHRPVYGLFTAKLTVID 817
+ SDH+PV F K+ +D
Sbjct: 909 VTESDHKPVRCKFHVKIEHVD 929
>At3g63240 [U] KOG0565 Inositol polyphosphate 5-phosphatase and related
proteins
Length = 574
Score = 135 bits (341), Expect = 2e-31
Identities = 81/235 (34%), Positives = 124/235 (52%), Gaps = 17/235 (7%)
Query: 595 KYHAVFNSQLGGLALLVFTDEENKSRIKHIEGDMKKTGFGGISSNKGAIAVHLWLSNTKF 654
KY V + Q+ G+ L V+ + + + +++ G G NKG+I++ + + T F
Sbjct: 277 KYCLVASKQMVGIFLTVWVKSDLRDSVNNLKVSCVGRGLMGYLGNKGSISISMSVHQTSF 336
Query: 655 CFVVSHLSAGLENVEQ--RHNDYKSIAKHIRFSKGTR---------IKDHDGVIWMGDFN 703
CFV SHL++G + ++ R++D I + RF + I +HD VIW+GD N
Sbjct: 337 CFVCSHLTSGQKEGDELRRNSDVLEILRKTRFPRVNNAGDDKSPQMISEHDRVIWLGDLN 396
Query: 704 FRILLSNDDVRQAIIDKNYHRLFEKDQLNQQMISGESFPFFDEMEITFPPTYKFNPGTDV 763
+RI LS + + +++ L EKDQL + G F + E I FPPTYK++ +D+
Sbjct: 397 YRIALSYRSAKALVEMRDWRALLEKDQLRIEQRKGCVFEGWKEGTIYFPPTYKYSNNSDI 456
Query: 764 YDTSE-----KMRIPAWTDRILSRGEILRQELYGSAEDIVFSDHRPVYGLFTAKL 813
Y + K R PAW DRIL G + Q Y E FSDHRPVY LF+ ++
Sbjct: 457 YAGDDRLPKAKRRTPAWCDRILWHGSGISQLSYVRGES-RFSDHRPVYSLFSVEI 510
>At2g31830 [U] KOG0565 Inositol polyphosphate 5-phosphatase and related
proteins
Length = 1144
Score = 135 bits (341), Expect = 2e-31
Identities = 106/392 (27%), Positives = 173/392 (44%), Gaps = 63/392 (16%)
Query: 500 PLHIYVTRFLRQRRHEYTFEKEISIFAGTFNVN-GKLSKEKLEGWLKPENESPDLYVIGL 558
PL + L Q+ Y + + I GT+NV G+ S+ L WL + IGL
Sbjct: 558 PLDSLIRTELSQKEMAYARQDSVKILIGTWNVGEGRASRGALVSWLGSAVSDVGIVAIGL 617
Query: 559 EEIVELSPGHMLATDPY---------IKTFWEKKLLSEINSYNDKKYHAVFNSQLGGLAL 609
+E V++ G + + + +W + + ++ N + + + QL GL +
Sbjct: 618 QE-VDMGAGFLAMSTAKETVGVEGSAVGQWWLDAIGNALDERNT--FERMGSRQLAGLLI 674
Query: 610 LVFTDEENKSRIKHIEGDMKKTGFGGISSNKGAIAVHLWLSNTKFCFVVSHLSAGLENVE 669
++ + ++ + ++ GFG NKG + + + + + CFV HL+A LE V
Sbjct: 675 SLWVRKSIRTHVGDLDVAAVPCGFGRAIGNKGGVGLRIRVYDRIMCFVNCHLAAHLEAVT 734
Query: 670 QRHNDYKSIAKHIRFSKGTRI----------------------------KDH----DGVI 697
+R+ D+ I + + FSKG + K H D V
Sbjct: 735 RRNADFNHIYRSMVFSKGQSVYTAAAAGASTSAQALKNNPNTNNSTEEEKSHLASADLVA 794
Query: 698 WMGDFNFRIL-LSNDDVRQAIIDKNYHRLFEKDQLNQQMISGESFPFFDEMEITFPPTYK 756
+ GDFN+R+ ++ D+ R I +++ L EKDQL Q+M G+ F E ITFPPTYK
Sbjct: 795 FFGDFNYRLFGITYDEARDFISHRSFDWLREKDQLRQEMNEGKVFQGMREALITFPPTYK 854
Query: 757 F---NPGTDVYDTSEKMRIPAWTDRILSRGE--------------ILRQELYGSAEDIVF 799
F PG YD+ EK RIPAW DR++ R + +Y + D+
Sbjct: 855 FEKNKPGLGGYDSGEKKRIPAWCDRVIYRDNQSISYTECSLKCPVVSSTIMYEACMDVTE 914
Query: 800 SDHRPVYGLFTAKLTVIDEPKKAKLVASIKDS 831
SDH+PV A + D+ + + + I S
Sbjct: 915 SDHKPVRCKLHANIAHTDKSVRRQELGKIVKS 946
>At4g18010 [U] KOG0565 Inositol polyphosphate 5-phosphatase and related
proteins
Length = 595
Score = 134 bits (337), Expect = 7e-31
Identities = 85/251 (33%), Positives = 130/251 (50%), Gaps = 15/251 (5%)
Query: 584 LLSEINSYND-KKYHAVFNSQLGGLALLVFTDEENKSRIKHIEGDMKKTGFGGISSNKGA 642
L+ E D +KY + + Q+ G+ + V+ + + +++ G G NKG+
Sbjct: 325 LVEECRKVKDSQKYVRIVSKQMVGIYVSVWIRRRLRRHVNNLKVSPVGVGLMGYMGNKGS 384
Query: 643 IAVHLWLSNTKFCFVVSHLSAG-LENVEQRHN-DYKSIAKHIRFS------KGTRIKDHD 694
+++ + L ++ CFV SHL++G + EQR N D I + RF+ + I HD
Sbjct: 385 VSISMTLYQSRMCFVCSHLTSGHKDGAEQRRNADVYEIIRRTRFASVLDTDQPRTIPCHD 444
Query: 695 GVIWMGDFNFRILLSNDDVRQAIIDKNYHRLFEKDQLNQQMISGESFPFFDEMEITFPPT 754
V W GD N+R+ +S+ +VR+ + K + L DQL +++ G F + E I FPPT
Sbjct: 445 QVFWFGDLNYRLNMSDGEVRKLVSQKRWDELKNSDQLIRELRRGHVFDGWREGPIKFPPT 504
Query: 755 YKFNPGTDVY-----DTSEKMRIPAWTDRILSRGEILRQELYGSAEDIVFSDHRPVYGLF 809
YK+ +D Y EK R PAW DRIL G+ +RQE Y +E I SDHRPV +F
Sbjct: 505 YKYEFDSDRYAGENLREPEKKRAPAWCDRILWLGKGIRQECYKRSE-IRMSDHRPVTSIF 563
Query: 810 TAKLTVIDEPK 820
+ V D K
Sbjct: 564 NVGVEVFDHRK 574
>At1g71710 [U] KOG0565 Inositol polyphosphate 5-phosphatase and related
proteins
Length = 655
Score = 131 bits (330), Expect = 4e-30
Identities = 78/236 (33%), Positives = 122/236 (51%), Gaps = 12/236 (5%)
Query: 596 YHAVFNSQLGGLALLVFTDEENKSRIKHIEGDMKKTGFGGISSNKGAIAVHLWLSNTKFC 655
Y + + Q+ G+ L ++ + I+++ G G NKGA++V + ++ T FC
Sbjct: 399 YVRLVSKQMVGILLTIWVKRSLRKHIQNVRVSTVGVGVMGYIGNKGAVSVSMSINQTFFC 458
Query: 656 FVVSHLSAGLENVEQ--RHNDYKSIAKHIRFSKGTR------IKDHDGVIWMGDFNFRIL 707
F+ +HL+AG V+Q R+ D I K F + I DH+ +IW+GD N+R+
Sbjct: 459 FINTHLTAGEREVDQIKRNADVHEIHKRTVFHSVSALGLPKLIYDHERIIWLGDLNYRLS 518
Query: 708 LSNDDVRQAIIDKNYHRLFEKDQLNQQMISGESFPFFDEMEITFPPTYKFNPGTDVY--- 764
S + R I + + +L E DQL ++ G +F + E + FPPTYK+ +D Y
Sbjct: 519 SSYEKTRDLISKREWSKLLEYDQLVKEYRKGRAFDGWSEGTLHFPPTYKYQANSDEYTAN 578
Query: 765 DTSEKMRIPAWTDRILSRGEILRQELYGSAEDIVFSDHRPVYGLFTAKLTVIDEPK 820
D R PAW DR+LS G+ +R Y E FSDHRPV ++ A++ V K
Sbjct: 579 DGKAPKRTPAWCDRVLSYGKGMRLVHYRRTEQ-KFSDHRPVTAIYMAEVEVFSARK 633
>Hs5031799 [U] KOG0565 Inositol polyphosphate 5-phosphatase and related
proteins
Length = 1188
Score = 131 bits (329), Expect = 6e-30
Identities = 98/340 (28%), Positives = 154/340 (44%), Gaps = 44/340 (12%)
Query: 507 RFLRQRRHEYTFEKE---ISIFAGTFNVNGKLSKEKLEGWLKPENESP-----------D 552
+ L+Q +++++ + E I+IF GT+N+ +K+ W + + D
Sbjct: 385 QLLQQMKNKHSEQPEPDMITIFIGTWNMGNAPPPKKITSWFLSKGQGKTRDDSADYIPHD 444
Query: 553 LYVIGLEEIVELSPGHMLATDPYIKTFWEKKLLSEINSYNDKKYHAVFNSQLGGLALLVF 612
+YVIG +E DP + W + L + + V L + ++V
Sbjct: 445 IYVIGTQE------------DPLSEKEWLEILKHSLQEITSVTFKTVAIHTLWNIRIVVL 492
Query: 613 TDEENKSRIKHIEGDMKKTGFGGISSNKGAIAVHLWLSNTKFCFVVSHLSAGLENVEQRH 672
E+++RI HI D KTG NKGA+ V + T FV SHL++G E +R+
Sbjct: 493 AKPEHENRISHICTDNVKTGIANTLGNKGAVGVSFMFNGTSLGFVNSHLTSGSEKKLRRN 552
Query: 673 NDYKSIAKHI-----RFSKGTRIKDHDGVIWMGDFNFRILLSN---DDVRQAIIDKNYHR 724
+Y +I + + + S + W GD N+R+ L + + Q I + Y
Sbjct: 553 QNYMNILRFLALGDKKLSPFNITHRFTHLFWFGDLNYRVDLPTWEAETIIQKIKQQQYAD 612
Query: 725 LFEKDQLNQQMISGESFPFFDEMEITFPPTYKFNPGT-DVY------DTSEKMRIPAWTD 777
L DQL + + F F+E EITF PTY+F T D Y T K +P+W D
Sbjct: 613 LLSHDQLLTERREQKVFLHFEEEEITFAPTYRFERLTRDKYAYTKQKATGMKYNLPSWCD 672
Query: 778 RILSRGEILRQ---ELYGSAEDIVFSDHRPVYGLFTAKLT 814
R+L + L + YGS DI+ SDH PV+ F A +T
Sbjct: 673 RVLWKSYPLVHVVCQSYGSTSDIMTSDHSPVFATFEAGVT 712
>7294594 [U] KOG0565 Inositol polyphosphate 5-phosphatase and related
proteins
Length = 747
Score = 130 bits (326), Expect = 1e-29
Identities = 99/332 (29%), Positives = 150/332 (44%), Gaps = 58/332 (17%)
Query: 519 EKEISIFAGTFNVNGKLSKEKLEGWLKPENES--PDLYVIGLEEIVELSPGHMLATDPYI 576
+KEI++F GT+N+NG ++L ++ P N PD+ V+G +E +T
Sbjct: 388 QKEITVFVGTWNMNGHSPPKQLNDFVLPANVEHVPDIVVMGTQE----------STPDRF 437
Query: 577 KTFWEKKLLSEINSYNDKKYHAVFNSQ-LGGLALLVFTDEENKSRIKHIEGDMKKTGFGG 635
+ WE + + H +F++ LG L L V+ + E G
Sbjct: 438 E--WEVTIQETLGPS-----HVLFHATTLGTLHLAVYMRRDLIWYCSVPEDASMSVRTGS 490
Query: 636 ISSNKGAIAVHLWLSNTKFCFVVSHLSAGLENVEQRHNDYKSIAKHIRFSKGTRIKDH-- 693
KGA+A+ L T FV SHL+A + V++R +D K I + + + H
Sbjct: 491 AFRTKGAVAISFCLFGTSMLFVTSHLTAHQQKVKERVSDVKRIINALDLPRNLPNQRHKN 550
Query: 694 -------DGVIWMGDFNFRILLSNDDVRQAIIDKNY-------HRLFEKDQLNQQMISGE 739
D V W GD NFR+ + + + I + + H DQL + G
Sbjct: 551 KDVTQNFDNVFWCGDLNFRLGEPREKLLEWIQNTKFPLPSHLPHGYMHTDQLTSVLADGA 610
Query: 740 SFPFFDEMEITFPPTYKFNPGTDVYDTSEKMRIPAWTDRIL-----SRGEILRQE----- 789
+F F E ITFPPTYK++PG+ +DTS K R PA+TDRIL +G ++R++
Sbjct: 611 AFRGFMEANITFPPTYKYDPGSQNFDTSSKQRAPAYTDRILYKYRQMQGLVIRRQTLVPG 670
Query: 790 ------------LYGSAEDIVFSDHRPVYGLF 809
LY S I SDH+PV+ LF
Sbjct: 671 VSTPTQPHVQCLLYDSVPSITTSDHKPVWALF 702
>At1g05630 [U] KOG0565 Inositol polyphosphate 5-phosphatase and related
proteins
Length = 1136
Score = 129 bits (325), Expect = 2e-29
Identities = 102/387 (26%), Positives = 171/387 (43%), Gaps = 59/387 (15%)
Query: 500 PLHIYVTRFLRQRRHEYTFEKEISIFAGTFNVN-GKLSKEKLEGWLKPENESPDLYVIGL 558
PL + L Q+ Y + + I GT+NV G+ S + L WL + +GL
Sbjct: 549 PLDNIIRTELSQKETLYARQDNVRILIGTWNVGQGRASHDALMSWLGSVTSDVGIVAVGL 608
Query: 559 EEIVELSPGHMLATDPYIKTFWEKKLLSE-----INSYNDKK--YHAVFNSQLGGLALLV 611
+E VE+ G + + E + + I D+K + + + QL GL + +
Sbjct: 609 QE-VEMGAGFLAMSAAKETVGLEGSAVGQWWIDAIGKALDEKNTFERMGSRQLAGLLISL 667
Query: 612 FTDEENKSRIKHIEGDMKKTGFGGISSNKGAIAVHLWLSNTKFCFVVSHLSAGLENVEQR 671
+ ++ ++ + ++ GFG NKG + + + + + CFV HL+A LE V +R
Sbjct: 668 WARKDIRTHVGDLDVAAVPCGFGRAIGNKGGVGLRIRVYDRIMCFVNCHLAAHLEAVNRR 727
Query: 672 HNDYKSIAKHIRFSKGTRIKDH--------------------------------DGVIWM 699
+ D+ I + + FS+G + + D V +
Sbjct: 728 NADFNHIFRLMVFSRGQNLSNAAAAGVSTSAYTTKSNTIPSTGAEEIKSDLAAADMVAFF 787
Query: 700 GDFNFRIL-LSNDDVRQAIIDKNYHRLFEKDQLNQQMISGESFPFFDEMEITFPPTYKF- 757
GDFN+R+ ++ D+ R I +++ L E+DQL +M G+ F E ITFPPTYKF
Sbjct: 788 GDFNYRLFGITYDEARDFISQRSFDWLRERDQLRAEMKVGKVFQGMREALITFPPTYKFE 847
Query: 758 --NPGTDVYDTSEKMRIPAWTDRILSRGE--------------ILRQELYGSAEDIVFSD 801
G YD+ EK RIPAW DR++ R + +Y + D+ SD
Sbjct: 848 RNRSGLGGYDSGEKKRIPAWCDRVIYRDTQSSPFSESNLQCPVVSSVIMYEACMDVTESD 907
Query: 802 HRPVYGLFTAKLTVIDEPKKAKLVASI 828
H+PV F A + +D+ + + + I
Sbjct: 908 HKPVRCKFHATIAHVDKSVRRQELGKI 934
>Hs20537935 [U] KOG0565 Inositol polyphosphate 5-phosphatase and related
proteins
Length = 799
Score = 129 bits (324), Expect = 2e-29
Identities = 96/335 (28%), Positives = 147/335 (43%), Gaps = 41/335 (12%)
Query: 509 LRQRRHEYTFEKEISIFAGTFNVNGKLSKEKLEGWLKPENESP-----------DLYVIG 557
++ + E I+IF GT+N+ +K+ W + + D+YVIG
Sbjct: 1 MKNKHSEQPEPDMITIFIGTWNMGNAPPPKKITSWFLSKGQGKTRDDSADYIPHDIYVIG 60
Query: 558 LEEIVELSPGHMLATDPYIKTFWEKKLLSEINSYNDKKYHAVFNSQLGGLALLVFTDEEN 617
+E DP + W + L + + V L + ++V E+
Sbjct: 61 TQE------------DPLSEKEWLEILKHSLQEITSVTFKTVAIHTLWNIRIVVLAKPEH 108
Query: 618 KSRIKHIEGDMKKTGFGGISSNKGAIAVHLWLSNTKFCFVVSHLSAGLENVEQRHNDYKS 677
++RI HI D KTG NKGA+ V + T FV SHL++G E +R+ +Y +
Sbjct: 109 ENRISHICTDNVKTGIANTLGNKGAVGVSFMFNGTSLGFVNSHLTSGSEKKLRRNQNYMN 168
Query: 678 IAKHI-----RFSKGTRIKDHDGVIWMGDFNFRILLSN---DDVRQAIIDKNYHRLFEKD 729
I + + + S + W GD N+R+ L + + Q I + Y L D
Sbjct: 169 ILRFLALGDKKLSPFNITHRFTHLFWFGDLNYRVDLPTWEAETIIQKIKQQQYADLLSHD 228
Query: 730 QLNQQMISGESFPFFDEMEITFPPTYKFNPGT-DVY------DTSEKMRIPAWTDRILSR 782
QL + + F F+E EITF PTY+F T D Y T K +P+W DR+L +
Sbjct: 229 QLLTERREQKVFLHFEEEEITFAPTYRFERLTRDKYAYTKQKATGMKYNLPSWCDRVLWK 288
Query: 783 GEILRQ---ELYGSAEDIVFSDHRPVYGLFTAKLT 814
L + YGS DI+ SDH PV+ F A +T
Sbjct: 289 SYPLVHVVCQSYGSTSDIMTSDHSPVFATFEAGVT 323
>At1g47510 [U] KOG0565 Inositol polyphosphate 5-phosphatase and related
proteins
Length = 331
Score = 127 bits (318), Expect = 1e-28
Identities = 90/286 (31%), Positives = 146/286 (50%), Gaps = 30/286 (10%)
Query: 528 TFNVNGKLSKEKLEGWLKPENESPDLYVIGLEEIVELSPGHMLATDPYIKTFWEKKLLSE 587
T+N+NG +S E L + E + DL V+GL+E + + +L T
Sbjct: 57 TWNMNGNVSYEDLVELVGKERKF-DLLVVGLQEAPKANVDQLLQTA-------------- 101
Query: 588 INSYNDKKYHAVFNSQLGGLALLVFTDEENKSRIKHIEGDMKKTGFGG--ISSNKGAIAV 645
+ + + ++L + L +F + + + +K ++ + G G I KGA+A+
Sbjct: 102 ----SSPTHELLGKAKLQSVQLYLFGPKNSHTLVKELKAERYSVGGCGGLIGRKKGAVAI 157
Query: 646 HLWLSNTKFCFVVSHLSAGLENVEQRHNDYKSIAKHIRFSKGTRIKDHDGVIWMGDFNFR 705
+ + K F+ HLSA + V+QR+ + + IA + + R +D +W+GD N+R
Sbjct: 158 RINYDDIKMVFISCHLSAHAKKVDQRNTELRHIANSL-LPRDKRKRDL--TVWLGDLNYR 214
Query: 706 IL-LSNDDVRQAIIDKNYHRLFEKDQLNQQMISGESFPFFDEMEITFPPTYKFNPGTDVY 764
I +SN VR I + L KDQL Q+ GE F + E + F PTYK+N G+ Y
Sbjct: 215 IQDVSNHPVRSLIQNHLQSVLVSKDQLLQEAERGEIFKGYSEGTLGFKPTYKYNVGSSDY 274
Query: 765 DTSEKMRIPAWTDRILSR---GEILRQEL--YGSAEDIVFSDHRPV 805
DTS K+R+PAWTDRIL + + ++ L Y S + + SDH+PV
Sbjct: 275 DTSHKIRVPAWTDRILFKIQDTDNIQATLHSYDSIDQVYGSDHKPV 320
>Hs4755142_1 [U] KOG0565 Inositol polyphosphate 5-phosphatase and related
proteins
Length = 1139
Score = 124 bits (312), Expect = 5e-28
Identities = 92/335 (27%), Positives = 143/335 (42%), Gaps = 43/335 (12%)
Query: 509 LRQRRHEYTFEKE-ISIFAGTFNVNGKLSKEKLEGWLKPENESP-----------DLYVI 556
L + +H E + IS+F GT+N+ + + W + D+YV
Sbjct: 410 LMKNKHSKQDEPDMISVFIGTWNMGSVPPPKNVTSWFTSKGLGKTLDEVTVTIPHDIYVF 469
Query: 557 GLEEIVELSPGHMLATDPYIKTFWEKKLLSEINSYNDKKYHAVFNSQLGGLALLVFTDEE 616
G +E + W L + D Y + L + + V E
Sbjct: 470 GTQE------------NSVGDREWLDLLRGGLKELTDLDYRPIAMQSLWNIKVAVLVKPE 517
Query: 617 NKSRIKHIEGDMKKTGFGGISSNKGAIAVHLWLSNTKFCFVVSHLSAGLENVEQRHNDYK 676
+++RI H+ KTG NKGA+ V + T F FV HL++G E +R+ +Y
Sbjct: 518 HENRISHVSTSSVKTGIANTLGNKGAVGVSFMFNGTSFGFVNCHLTSGNEKTARRNQNYL 577
Query: 677 SIAKHIRFSKGTRIKD-------HDGVIWMGDFNFRILLSNDDVRQAIIDKNYHRLFEKD 729
I + + S G R + + W GD N+R+ + ++ I K + L D
Sbjct: 578 DILRLL--SLGDRQLNAFDISLRFTHLFWFGDLNYRLDMDIQEILNYISRKEFEPLLRVD 635
Query: 730 QLNQQMISGESFPFFDEMEITFPPTYKFNPGT-DVY------DTSEKMRIPAWTDRILSR 782
QLN + + F F E EI+FPPTY++ G+ D Y T + +P+W DRIL +
Sbjct: 636 QLNLEREKHKVFLRFSEEEISFPPTYRYERGSRDTYAWHKQKPTGVRTNVPSWCDRILWK 695
Query: 783 G---EILRQELYGSAEDIVFSDHRPVYGLFTAKLT 814
+ YG +DIV SDH PV+G F +T
Sbjct: 696 SYPETHIICNSYGCTDDIVTSDHSPVFGTFEVGVT 730
>At1g34120 [U] KOG0565 Inositol polyphosphate 5-phosphatase and related
proteins
Length = 605
Score = 119 bits (299), Expect = 2e-26
Identities = 75/246 (30%), Positives = 126/246 (50%), Gaps = 15/246 (6%)
Query: 588 INSYNDKKYHAVFNSQLGGLALLVFTDEENKSRIKHIEGDMKKTGFGGISSNKGAIAVHL 647
I + Y + + Q+ G+ L ++ + I ++ G G NKG+++V +
Sbjct: 345 ITNLRKPSYVRIVSKQMVGVFLTIWVRRNLRKHISNLCVSTVGVGIMGYIGNKGSVSVSM 404
Query: 648 WLSNTKFCFVVSHLSAGLENVEQ--RHNDYKSIAKHIRFSKGT--------RIKDHDGVI 697
+ T FCF+ +HLS+G ++ +Q R++D + I + +F + I +H+ +I
Sbjct: 405 SIYQTPFCFLCTHLSSGEKDTDQEKRNDDVREIHRRTQFLPHSLNANELPRSICNHE-II 463
Query: 698 WMGDFNFRILLSNDDVRQAIIDKNYHRLFEKDQLNQQMISGESFPFFDEMEITFPPTYKF 757
W+GD N+RI LS + + I K + RL E DQL+++M G F + E + F PTYK+
Sbjct: 464 WLGDLNYRINLSYEKTHELIARKEWQRLVEYDQLSREMTKGNLFEGWSEGTLDFAPTYKY 523
Query: 758 NPGTDVY---DTSEKMRIPAWTDRILSRGEILRQELYGSAEDIVFSDHRPVYGLFTAKLT 814
++ Y D R PAW DRI+ G+ ++ Y +I SDHRPV F A++
Sbjct: 524 EIDSENYIGDDPESGKRRPAWCDRIIWNGKGMKLFNY-RRNEIKLSDHRPVTATFLAEVE 582
Query: 815 VIDEPK 820
V+ K
Sbjct: 583 VLSPRK 588
>Hs18765709 [U] KOG0565 Inositol polyphosphate 5-phosphatase and related
proteins
Length = 448
Score = 117 bits (294), Expect = 6e-26
Identities = 103/320 (32%), Positives = 148/320 (46%), Gaps = 35/320 (10%)
Query: 520 KEISIFAGTFNVNGKLSKEKLEGWLKPENESP--DLYVIGLEEIVELSPGHM-LATDPYI 576
+ +SI T+NV L L+ N + D+YVIGL+E L+ G + L +D
Sbjct: 12 RRLSIHVVTWNVASAAPPLDLSDLLQLNNRNLNLDIYVIGLQE---LNSGIISLLSDAAF 68
Query: 577 KTFWEKKLLSEINSYNDKKYHAVFNSQLGGLALLVFTDEENKSRIKHIEGDMKKTGFGGI 636
W L+ ++ + K V + ++ G+ LLVF ++ I+ + TG G
Sbjct: 69 NDSWSSFLMDVLSPLSFIK---VSHVRMQGILLLVFAKYQHLPYIQILSTKSTPTGLFGY 125
Query: 637 SSNKGAIAVHLWLSNTKFCFVVSHLSAGLENVEQRHNDYKSIAKHIRFSKGT---RIKDH 693
NKG + + L L + HL + N QR + I + ++ +G I DH
Sbjct: 126 WGNKGGVNICLKLYGYYVSIINCHLPPHISNNYQRLEHFDRILE-MQNCEGRDIPNILDH 184
Query: 694 DGVIWMGDFNFRIL-LSNDDVRQAIIDKNYHRLFEKDQLNQQMISGESFPFFDEMEITFP 752
D +IW GD NFRI VR++I ++ Y L+EKDQL+ F E + FP
Sbjct: 185 DLIIWFGDMNFRIEDFGLHFVRESIKNRCYGGLWEKDQLSIAKKHDPLLREFQEGRLLFP 244
Query: 753 PTYKFNPGTDVYDTSEKMRIPAWTDRILSRGEILRQEL-------------------YGS 793
PTYKF+ ++ YDTSEK R PAWTDRIL R + RQ Y S
Sbjct: 245 PTYKFDRNSNDYDTSEKKRKPAWTDRILWR--LKRQPCAGPDTPIPPASHFSLSLRGYSS 302
Query: 794 AEDIVFSDHRPVYGLFTAKL 813
SDH+PV G F +L
Sbjct: 303 HMTYGISDHKPVSGTFDLEL 322
>Hs9845291 [U] KOG0565 Inositol polyphosphate 5-phosphatase and related
proteins
Length = 644
Score = 113 bits (282), Expect = 2e-24
Identities = 95/321 (29%), Positives = 143/321 (43%), Gaps = 41/321 (12%)
Query: 516 YTFEKEISIFAGTFNVNG-KLSKEKLEGWLKPENE--SPDLYVIGLEEIVELSPGHMLAT 572
Y ++ +++F T+N+ G K L+ +L P + DLYVIG++E +
Sbjct: 293 YFPDRNVALFVATWNMQGQKELPPSLDEFLLPAEADYAQDLYVIGVQEGCSDTRE----- 347
Query: 573 DPYIKTFWEKKLLSEINSYNDKKYHAVFNSQLGGLALLVFTDEENKSRIKHIEGDMKKTG 632
WE +L + + Y + ++ G L + +F + +E T
Sbjct: 348 -------WETRLQETLGPH----YVLLSSAAHGVLYMSLFIRRDLIWFCSEVECSTVTTR 396
Query: 633 FGGISSNKGAIAVHLWLSNTKFCFVVSHLSAGLENVEQRHNDYKSIAKHI---------- 682
KGA+ + T F F+ SH ++G V +R DY + +
Sbjct: 397 IVSQIKTKGALGISFTFFGTSFLFITSHFTSGDGKVAERLLDYTRTVQALVLPRNVPDTN 456
Query: 683 --RFSKGTRIKDHDGVIWMGDFNFRILLSNDDVRQAIIDK----NYHRLFEKDQLNQQMI 736
R S D V W GDFNFR L V A++ + + L + DQL ++M
Sbjct: 457 PYRSSAADVTTRFDEVFWFGDFNFR-LSGGRTVVDALLCQGLVVDVPALLQHDQLIREMR 515
Query: 737 SGESFPFFDEMEITFPPTYKFNPGTDVYDTSEKMRIPAWTDRILSR----GEILRQELYG 792
G F F E +I F P+YKF+ G D YD++ K R P++TDR+L R G+I Y
Sbjct: 516 KGSIFKGFQEPDIHFLPSYKFDIGKDTYDSTSKQRTPSYTDRVLYRSRHKGDICPVS-YS 574
Query: 793 SAEDIVFSDHRPVYGLFTAKL 813
S I SDHRPVYGLF K+
Sbjct: 575 SCPGIKTSDHRPVYGLFRVKV 595
>Hs18765707 [U] KOG0565 Inositol polyphosphate 5-phosphatase and related
proteins
Length = 372
Score = 105 bits (261), Expect = 4e-22
Identities = 81/238 (34%), Positives = 112/238 (47%), Gaps = 26/238 (10%)
Query: 599 VFNSQLGGLALLVFTDEENKSRIKHIEGDMKKTGFGGISSNKGAIAVHLWLSNTKFCFVV 658
V + ++ G+ LLVF ++ I+ + TG G NKG + + L L +
Sbjct: 12 VSHVRMQGILLLVFAKYQHLPYIQILSTKSTPTGLFGYWGNKGGVNICLKLYGYYVSIIN 71
Query: 659 SHLSAGLENVEQRHNDYKSIAKHIRFSKGT---RIKDHDGVIWMGDFNFRIL-LSNDDVR 714
HL + N QR + I + ++ +G I DHD +IW GD NFRI VR
Sbjct: 72 CHLPPHISNNYQRLEHFDRILE-MQNCEGRDIPNILDHDLIIWFGDMNFRIEDFGLHFVR 130
Query: 715 QAIIDKNYHRLFEKDQLNQQMISGESFPFFDEMEITFPPTYKFNPGTDVYDTSEKMRIPA 774
++I ++ Y L+EKDQL+ F E + FPPTYKF+ ++ YDTSEK R PA
Sbjct: 131 ESIKNRCYGGLWEKDQLSIAKKHDPLLREFQEGRLLFPPTYKFDRNSNDYDTSEKKRKPA 190
Query: 775 WTDRILSRGEILRQEL-------------------YGSAEDIVFSDHRPVYGLFTAKL 813
WTDRIL R + RQ Y S SDH+PV G F +L
Sbjct: 191 WTDRILWR--LKRQPCAGPDTPIPPASHFSLSLRGYSSHMTYGISDHKPVSGTFDLEL 246
>Hs22068673 [U] KOG0565 Inositol polyphosphate 5-phosphatase and related
proteins
Length = 454
Score = 102 bits (254), Expect = 3e-21
Identities = 68/189 (35%), Positives = 92/189 (47%), Gaps = 19/189 (10%)
Query: 655 CFVVSHLSAGLENVEQRHNDYKSIAKHIRFSK--GTRIKDHDGVIWMGDFNFRILLSN-D 711
CF+ HL A ++ EQR +++++I +F I DHD V W GD NFRI +
Sbjct: 3 CFLNCHLPAHMDKAEQRKDNFQTILSLQQFQGPGAQGILDHDLVFWFGDLNFRIESYDLH 62
Query: 712 DVRQAIIDKNYHRLFEKDQLNQQMISGESFPFFDEMEITFPPTYKFNPGTDVYDTSEKMR 771
V+ AI H+L+EKDQLN + F E + F PT+KF+ GT+ YDTS K R
Sbjct: 63 FVKFAIDSDQLHQLWEKDQLNMAKNTWPILKGFQEGPLNFAPTFKFDVGTNKYDTSAKKR 122
Query: 772 IPAWTDRIL----------------SRGEILRQELYGSAEDIVFSDHRPVYGLFTAKLTV 815
PAWTDRIL S + Q Y S + SDH+PV F +
Sbjct: 123 KPAWTDRILWKVKAPGGGPSPSGRKSHRLQVTQHSYRSHMEYTVSDHKPVAAQFLLQFAF 182
Query: 816 IDEPKKAKL 824
D+ +L
Sbjct: 183 RDDMPLVRL 191
>CE00123 [U] KOG0565 Inositol polyphosphate 5-phosphatase and related
proteins
Length = 398
Score = 99.8 bits (247), Expect = 2e-20
Identities = 64/214 (29%), Positives = 110/214 (50%), Gaps = 9/214 (4%)
Query: 609 LLVFTDEENKSRIKHIEGDMKKTGFGGISSNKGAIAVHLWLSNT-KFCFVVSHLSAGLEN 667
+L+F ++ +IK I+ ++ GG++ +KG+I V L L++ FV SH G EN
Sbjct: 84 VLIFGRKQLIGQIKRIDYRFQRNTMGGLTGHKGSIGVRLQLASPYSIVFVDSHFIHGPEN 143
Query: 668 VEQRHNDYKSIAKHIRFSKGTRIKDHDGVIWMGDFNFRILLSNDDVRQAIIDKNYHRLFE 727
+R Y + ++ F + ++ W GDFNFR+ + V + I + + L +
Sbjct: 144 YGKRVEQYHT-NRNCSFPEDKSVR---AAFWFGDFNFRVEEDVNTVIRKIKNGTHLELLD 199
Query: 728 -KDQLNQQMISGESFPFFDEMEITFPPTYKFNPGTDVYDTSEKMRIPAWTDRILSRGEIL 786
++QL + ++ ++F F E +TF PTY+ GT D R+P+WTDRIL +G+ +
Sbjct: 200 TREQLKRALVERDAFIGFHEQPVTFEPTYRVTVGTTEQDGK---RVPSWTDRILYKGDGI 256
Query: 787 RQELYGSAEDIVFSDHRPVYGLFTAKLTVIDEPK 820
Y + + V SDH PV +F +P+
Sbjct: 257 TGLSYTNNKKAVASDHLPVVAMFRVTAPAAPKPQ 290
>7300754 [I] KOG1890 Phosphoinositide phosphatase SAC1
Length = 987
Score = 99.8 bits (247), Expect = 2e-20
Identities = 83/318 (26%), Positives = 148/318 (46%), Gaps = 33/318 (10%)
Query: 136 ERQLTEHPCGHLKMLISDGSFYYSNDFDITNSLQERGLVHRIEYTIDNQDQRYVWNYNQI 195
ER++TE K+ SFY+S D DITN+LQ + E + D+R+ WN + I
Sbjct: 188 ERRITEELH---KIFDETDSFYFSFDCDITNNLQRHEA--KSEESQSQPDERFFWNKHMI 242
Query: 196 SEIVQLRSRIAVQERPYFDSGSFLVFLVRGFCQTITDGISSSC---TLISRISTEGMNNL 252
+++ L + ++++ +++GF Q I + C L+SR S
Sbjct: 243 RDLINLNDK------------TWILPIIQGFMQVENCVIGNECFTLALVSRRSRHRAGTR 290
Query: 253 SEFKGIDQSGKVSNFVETEIIVQTRRNVFSYTMTGGDIPLNWELVEGQFLHGKKPKLLSK 312
+ +G+D+ G +N+VETE I+ R + S+T G +P+ W + + + P+L
Sbjct: 291 YKRRGVDEKGNCANYVETEQILSFRHHQLSFTQVRGSVPIYWS--QPGYKYRPPPRLDRG 348
Query: 313 ASTVQPSFDLHFDELMSKYGVVSIVNV------SKPKNDAYEAMINTYQKCASSKGIDLT 366
+ Q +F+LHF + + YG V IVN+ K DAY + K + + I +T
Sbjct: 349 VAETQQAFELHFTKELETYGRVCIVNLVEQSGKEKTIGDAYADHVI---KLNNDRLIYVT 405
Query: 367 LIEDSTSALNRIPHRIIYLLQQKIYEFGSFAYDM-DKKIYVGKQTGVFRISAVNLFKKLN 425
R + + L+ E G+ + D++ + Q VFR++ ++ + N
Sbjct: 406 FDFHDYCRGMRFEN-VSALIDAVGPEAGAMGFHWRDQRGMICNQKSVFRVNCMDCLDRTN 464
Query: 426 IVEKVISADVLELTINEL 443
+V+ I VLE + +L
Sbjct: 465 VVQTAIGKAVLESQLVKL 482
>CE28690 [U] KOG0565 Inositol polyphosphate 5-phosphatase and related
proteins
Length = 363
Score = 93.2 bits (230), Expect = 2e-18
Identities = 70/194 (36%), Positives = 96/194 (49%), Gaps = 21/194 (10%)
Query: 640 KGAIAVHLWLSNTKFCFVVSHLSAGLENVEQRHNDYKSIAKHIRFSKGTRIKDH------ 693
KGAIAV L L + HLS +QR DY + + +RF + R H
Sbjct: 148 KGAIAVCLRLYQRFIVLIGCHLSHATP--QQRIQDYAKVVRTLRFPQLARFHAHAKDEIF 205
Query: 694 --DGVIWMGDFNFRILL-SNDDVR--QAIIDKNYHRLFEKDQLNQQMISGESFPFFDEME 748
D V+W+GD NFR+ + SN D R + I +K + +FE ++L +F F E
Sbjct: 206 GSDVVLWIGDLNFRVTVESNVDWRDPEKITEKTFRDVFETEELASHRKKQLAFTDFKEAP 265
Query: 749 ITFPPTYKFNPGTDVYDTSEKMRIPAWTDRIL---SRGEILRQELYGSAEDIVFSDHRPV 805
I FPPT+KF P TD Y RIP++TDR+L E L+ Y SDH+ V
Sbjct: 266 IKFPPTHKFEPDTDNY---VPKRIPSFTDRVLFWVRNSEWLQNIQYDCMRGTTPSDHKAV 322
Query: 806 YGLFTAKLTVIDEP 819
+ F LTVI++P
Sbjct: 323 FATFW--LTVINKP 334
>YOL065c [U] KOG0565 Inositol polyphosphate 5-phosphatase and related
proteins
Length = 384
Score = 92.0 bits (227), Expect = 4e-18
Identities = 79/286 (27%), Positives = 132/286 (45%), Gaps = 41/286 (14%)
Query: 549 ESPDLYVIGLEEIVELSPGHMLATDPYIKTFWEKKLLSEINSYNDK--------KYHAVF 600
E DLYV+G +E+V + G A + + ++ + +N N+K +Y +
Sbjct: 43 ELQDLYVLGFQEVVPIWQGSFPAVN---RDLIDRITTTAVNCLNEKVSATQGDEQYSCLG 99
Query: 601 NSQLGGLALLVFTDEENKSRIKHIEGDMKKTGFGGISSN--KGAIAVHLWLSNT------ 652
+ LG + ++V N + +K + +K+ G G KG + ++
Sbjct: 100 VNSLGAITIIVLY---NNNALKVKDDILKRNGKCGWFGTHLKGGTLISFQMTRNGEENWE 156
Query: 653 KFCFVVSHLSA--GLENVEQRHNDYKSIAKHIRFSKGTRIKDHDGVIWMGDFNFRILLSN 710
+F ++ +HL+A G+ N QR +DYK I + S+ + D ++GD NFR+ +
Sbjct: 157 RFSYICAHLNANEGVNNRNQRIDDYKRIMSEVCDSE---VAKSDHFFFLGDLNFRVTSTY 213
Query: 711 DDVRQAIIDKNYHRLFEKDQLNQQMISGESFPF---FDEMEITFPPTYKFNP-GTDVYDT 766
D RL E + + GE P F E++ITFPPTYKF + Y+T
Sbjct: 214 DPTTNYSSTTTLRRLLENHEELNLLRKGEDEPLCKGFQELKITFPPTYKFKLFEKETYNT 273
Query: 767 SEKMRIPAWTDRILSRG----EILRQELYGS---AEDIVFSDHRPV 805
RIP+W DRIL + ++ Y S + ++FSDH+PV
Sbjct: 274 K---RIPSWCDRILYKSYAVPTFAQEGTYHSVPRSNALLFSDHQPV 316
>At1g65580 [U] KOG0565 Inositol polyphosphate 5-phosphatase and related
proteins
Length = 993
Score = 88.6 bits (218), Expect = 4e-17
Identities = 56/160 (35%), Positives = 84/160 (52%), Gaps = 18/160 (11%)
Query: 690 IKDHDGVIWMGDFNFRIL-LSNDDVRQAIIDKNYHRLFEKDQLNQQMISGESFPFFDEME 748
+ + D VI++GDFN+R+ ++ D+ R I + + L EKDQL+ +M +G F E
Sbjct: 637 LSEADMVIFLGDFNYRLDDITYDETRDFISQRCFDWLREKDQLHTEMEAGNVFQGMREAI 696
Query: 749 ITFPPTYKF---NPGTDVYDTSEKMRIPAWTDRILSRGE--------------ILRQELY 791
I FPPTYKF G YD+ EK RIPAW DRIL R + Y
Sbjct: 697 IRFPPTYKFERHQAGLAGYDSGEKKRIPAWCDRILYRDNKKHLGAECSLDCPVVSSISQY 756
Query: 792 GSAEDIVFSDHRPVYGLFTAKLTVIDEPKKAKLVASIKDS 831
+ ++ SDH+PV +F+ K+ +DE + + +I +S
Sbjct: 757 DACMEVTDSDHKPVRCVFSVKIARVDESVRRQEYGNIINS 796
>Hs7662414 [I] KOG1890 Phosphoinositide phosphatase SAC1
Length = 1132
Score = 85.5 bits (210), Expect = 4e-16
Identities = 83/349 (23%), Positives = 145/349 (40%), Gaps = 64/349 (18%)
Query: 136 ERQLTEHPCGHLKMLISDGSFYYSNDFDITNSLQERGLVHRIEYTI-DNQDQRYVWNYNQ 194
ER+L E LKM + SFYYS +D+TNS+Q + R + D R+ WN
Sbjct: 159 ERRLLEEL---LKMFMDSESFYYSLTYDLTNSVQRQSTGERDGRPLWQKVDDRFFWNKYM 215
Query: 195 ISEIVQLRSRIAVQERPYFDSGSFLVFLVRGFCQTI------------------TDGISS 236
I ++ ++ + D +++ +++GF Q T S
Sbjct: 216 IQDLTEIGTP---------DVDFWIIPMIQGFVQIEELVVNYTESSDDEKSSPETPPQES 266
Query: 237 SCT----------LISRISTEGMNNLSEFKGIDQSGKVSNFVETEIIVQTRRNVFSYTMT 286
+C LISR S + +G+D++G V+N+VETE ++ + S+ T
Sbjct: 267 TCVDDIHPRFLVALISRRSRHRAGMRYKRRGVDKNGNVANYVETEQLIHVHNHTLSFVQT 326
Query: 287 GGDIPLNWELVEGQFLHGKKPKLLSKASTVQPSFDLHFDELMSKYGVVSIVNV------S 340
G +P+ W V + + +P+L F HF+E ++ Y I+N+
Sbjct: 327 RGSVPVFWSQV--GYRYNPRPRLDRSEKETVAYFCAHFEEQLNIYKKQVIINLVDQAGRE 384
Query: 341 KPKNDAYEAMINTYQKCASSKGIDLTLIE-DSTSALNRIPHRIIYLLQQKIYEFGSFAYD 399
K DAY + + LT + D + + L IY+ D
Sbjct: 385 KIIGDAYLKQVLLFNNS------HLTYVSFDFHEHCRGMKFENVQTLTDAIYD---IILD 435
Query: 400 M-----DKKIYVGKQTGVFRISAVNLFKKLNIVEKVISADVLELTINEL 443
M D+ + KQ G+FR++ ++ + N+V+ I+ V+E + +L
Sbjct: 436 MKWCWVDEAGVICKQEGIFRVNCMDCLDRTNVVQAAIARVVMEQQLKKL 484
>SPBC19F5.03 [I] KOG1889 Putative phosphoinositide phosphatase
Length = 598
Score = 80.9 bits (198), Expect = 9e-15
Identities = 92/360 (25%), Positives = 147/360 (40%), Gaps = 53/360 (14%)
Query: 103 EEETIYQILNINFYCIDSDKYDSMFQDLSDIGYERQLTEHPCGHLKMLISDGSFYYSNDF 162
E+ + QIL Y + + L+D E L HLK G FY+S +
Sbjct: 66 EKSSAAQILGHKIYRVHKFEVIPYRNLLADDQDELDLYNLLQNHLKT----GPFYFSYTW 121
Query: 163 DITNSLQERGLVHRIEYTIDNQDQRYVWNYNQISEIVQLRSRIAVQERPYFDSGSFLVFL 222
D+TNSLQ I D+R+ WN + + L + + F+ +
Sbjct: 122 DLTNSLQRSCTDEGKASPILRSDKRFFWNEFASKDFIDLIGA-------HSEVSLFITPM 174
Query: 223 VRGF---CQTITDGISSSCTLISRISTEGMNNLSEFKGIDQSGKVSNFVETEIIV----Q 275
+ GF TI G + + LISR S + +G+D++G +NF ETE I +
Sbjct: 175 IYGFITSASTIVKGRTITLALISRRSKQRAGTRYFTRGLDENGNPANFNETEQITIVSDE 234
Query: 276 TRRNVFSYTMTGGDIPLNWELVEGQFLHGKKPKLLSKASTVQPSFDLHFDELMSKYG--- 332
+S+ T G +P W V L K + + AS + HFDE +S YG
Sbjct: 235 KSEVTYSHVQTRGSVPAFWAEVNN--LRYKPLMVANSASMAAAAAKKHFDEQISIYGDQV 292
Query: 333 VVSIVNV---SKPKNDAYEAMI-------------NTYQKCASSKGIDLTLIEDSTSALN 376
VV++VN P YE +I + +++C+ + ++L+ LN
Sbjct: 293 VVNLVNCKGHELPIKQLYENVIRRLDNPHIHYHYFDFHKECSHMRWDRVSLL------LN 346
Query: 377 RIPHRIIYLLQQKIYEFGSFAYDMDKKIYVGKQTGVFRISAVNLFKKLNIVEKVISADVL 436
I Q ++ E G D K + +Q GV R + ++ + N+V+ I VL
Sbjct: 347 EI--------QPELEEQGYTTLDTQKYRVLSRQNGVVRSNCMDCLDRTNVVQSCIGRWVL 398
>Hs7662338 [I] KOG1889 Putative phosphoinositide phosphatase
Length = 587
Score = 79.3 bits (194), Expect = 3e-14
Identities = 100/419 (23%), Positives = 169/419 (39%), Gaps = 59/419 (14%)
Query: 67 LFGLITVKGQVFIGIITSNKKVGS----PRWKLNEQDKVIEEETIYQILNINFYCIDSDK 122
+ G I + ++ +IT KVG WK + D + ++T+ + +I D+
Sbjct: 60 ILGTIHLVAGNYLIVITKKIKVGEFFSHVVWKATDFDVLSYKKTMLHLTDIQLQ--DNKT 117
Query: 123 YDSMFQDLSDIGYERQLTEHPCGHLKMLISDGSFYYSNDFDITNSLQERGLVH---RIEY 179
+ +M + ++ DG FY+S +D+T++LQ +
Sbjct: 118 FLAMLNHVLNV-------------------DG-FYFSTTYDLTHTLQRLSNTSPEFQEMS 157
Query: 180 TIDNQDQRYVWNYNQISEIVQLRSRIAVQERPYFDSGSFLVFLVRGFCQTITDGISSSCT 239
++ DQR+VWN + + E+ A E F F+ C +G
Sbjct: 158 LLERADQRFVWNGHLLRELS------AQPEVHRFALPVLHGFITMHSCSI--NGKYFDWI 209
Query: 240 LISRISTEGMNNLSEFKGIDQSGKVSNFVETEIIVQTRRNVFSYTMTGGDIPLNWELVEG 299
LISR S +GID G +NFVETE IV + S+ T G IP+ W +
Sbjct: 210 LISRRSCFRAGVRYYVRGIDSEGHAANFVETEQIVHYNGSKASFVQTRGSIPVFWS--QR 267
Query: 300 QFLHGKKPKLLSKASTVQPSFDLHFDELMSKYGVVSIVNVSKPKNDAYEAMINTYQKCAS 359
L K +SK + F HFD + YG I+N+ K + + + T+ S
Sbjct: 268 PNLKYKPLPQISKVANHMDGFQRHFDSQVIIYGKQVIINLINQKG-SEKPLEQTFATMVS 326
Query: 360 SKGIDL---TLIEDSTSALNRIPHRIIYLLQQKIY---EFGSFAYDMDKKIYVGKQTGVF 413
S G + + N R+ LL Q E F D ++ V Q GVF
Sbjct: 327 SLGSGMMRYIAFDFHKECKNMRWDRLSILLDQVAEMQDELSYFLVDSAGQV-VANQEGVF 385
Query: 414 RISAVNLFKKLNIVEKVISADVLELTI---------NELEEKDISSDFWKSHDSLWKSN 463
R + ++ + N+++ +++ L+ + +LEE+D +F K + + W N
Sbjct: 386 RSNCMDCLDRTNVIQSLLARRSLQAQLQRLGVLHVGQKLEEQD---EFEKIYKNAWADN 441
>7292047 [I] KOG1889 Putative phosphoinositide phosphatase
Length = 592
Score = 79.0 bits (193), Expect = 3e-14
Identities = 86/349 (24%), Positives = 152/349 (42%), Gaps = 36/349 (10%)
Query: 135 YERQLTEHPCGHLKMLISDGSFYYSNDFDITNSLQERGLVHR----IEYTIDNQDQRYVW 190
++R+ E+ L+ + FY+S +D+TNSLQ + V + + + +QR+VW
Sbjct: 109 FQRKENENYLRLLRQTLDTKFFYFSYRYDLTNSLQRQREVAQSRPEVSGLLQRAEQRFVW 168
Query: 191 NYNQISEIVQLRSRIAVQERPYFDSGSFLVFLVRGFC---QTITDGISSSCTLISRISTE 247
N + + + F + LV GF Q +G + ++I+R S +
Sbjct: 169 NGYVLRQFNCDKME------------KFQLPLVLGFVSINQVQINGQTFFWSIITRRSVQ 216
Query: 248 GMNNLSEFKGIDQSGKVSNFVETEIIVQTRRNVFSYTMTGGDIPLNWELVEGQFLHGKKP 307
+G D+ G V+NFVETE IV+ + + T G +P +W + L K
Sbjct: 217 RAGTRLFCRGSDEQGHVANFVETEQIVEFNGQLTGFVQTRGSMPFHWHQLPN--LRYKPR 274
Query: 308 KLLSKASTVQPSFDLHFDELMSKYGVVSIVNVSKPKNDAYEAMINTYQKCASSKGIDLTL 367
+L + LHF E + YG VN+ K A + TY + G
Sbjct: 275 PVLVPGKDHLAACGLHFKEQIRLYGNNVAVNLVDHKG-AEGELEATYARLVREMGNPQVR 333
Query: 368 IE--DSTSALNRIP-HRIIYLLQQKIYE---FGSFAYDMDKKIYVGKQTGVFRISAVNLF 421
E D S ++ R+ L+ + +E FG + D K+ V QTGVFR + ++
Sbjct: 334 YESFDFHSECRKMRWDRLNILIDRLAHEQDQFGVYHVFDDGKL-VSTQTGVFRTNCIDCL 392
Query: 422 KKLNIVEKVISADVLELTINEL------EEKDISSDFWKS-HDSLWKSN 463
+ N+V+ +++ L + +L ++ + +SD ++S +W N
Sbjct: 393 DRTNVVQSMLARRSLTAVLQKLGVLHVGQKVEHASDIFESIFKGVWADN 441
>YKL212w [I] KOG1889 Putative phosphoinositide phosphatase
Length = 623
Score = 73.6 bits (179), Expect = 1e-12
Identities = 81/350 (23%), Positives = 151/350 (43%), Gaps = 53/350 (15%)
Query: 147 LKMLISDGSFYYSNDFDITNSLQERGLVHRIEYTIDNQDQRYVWNYNQISEIVQLRSRIA 206
L++ + + +FY+S +D+TNSLQ V + D+R+ WN+ ++ R
Sbjct: 115 LELHLKNSTFYFSYTYDLTNSLQRNEKVGPAA-SWKTADERFFWNHYLTEDL-----RNF 168
Query: 207 VQERPYFDSGSFLVFLVRGFCQTITDGISSS---CTLISRISTEGMNNLSEFKGIDQSGK 263
+ P D SF+ ++ G+ +T+ ++++ LI+R S +G+D+ G
Sbjct: 169 AHQDPRID--SFIQPVIYGYAKTVDAVLNATPIVLGLITRRSIFRAGTRYFRRGVDKDGN 226
Query: 264 VSNFVETEIIV------QTRRNVFSYTMTGGDIPLNWELVEGQFLHGKKPKLLSKASTVQ 317
V NF ETE I+ + +VFS+ T G +P+ W + KP L+ +++
Sbjct: 227 VGNFNETEQILLAENPESEKIHVFSFLQTRGSVPIYWAEINNL---KYKPNLVLGENSLD 283
Query: 318 PSFDLHFDELMSKYGVVSIVNV------SKPKNDAYEAMINTYQKCASSKGIDLTLIEDS 371
+ HFD+ YG +VN+ P + YE++++ + I +
Sbjct: 284 AT-KKHFDQQKELYGDNYLVNLVNQKGHELPVKEGYESVVH----ALNDPKIHYVYFDFH 338
Query: 372 TSALNRIPHRIIYLLQQKIYEFGSFAYDMDKKI---------YVGKQTGVFRISAVNLFK 422
HR + LL + + G D K+ V +Q V R + ++
Sbjct: 339 HECRKMQWHR-VKLLIDHLEKLGLSNEDFFHKVIDSNGNTVEIVNEQHSVVRTNCMDCLD 397
Query: 423 KLNIVEKVISADVLELTINELEEKDI--SSDFWK-------SHDSLWKSN 463
+ N+V+ V++ VL+ E E D+ + W+ S+ +LW N
Sbjct: 398 RTNVVQSVLAQWVLQ---KEFESADVVATGSTWEDNAPLLTSYQNLWADN 444
>At3g51830 [I] KOG1889 Putative phosphoinositide phosphatase
Length = 599
Score = 70.9 bits (172), Expect = 9e-12
Identities = 94/425 (22%), Positives = 171/425 (40%), Gaps = 47/425 (11%)
Query: 62 TTFTALFGLITVKGQVFIGIITSNKKVGSPRWKLNEQDKVIEEETIYQILNINFYCIDSD 121
+T + G I + ++ +ITS ++VG+ I+++ + F +
Sbjct: 62 STIYGVGGTIRLLAGTYLLVITSREEVGN-----------FLGLPIFRVTAMKFLPCNEA 110
Query: 122 KYDSMFQDLSDIGYERQLTEHPCGHLKMLISDGSFYYSNDFDITNSLQER---------- 171
+ Q+ D Y R L L+ L + Y+S + D+T +LQ R
Sbjct: 111 LRFATAQEKKDETYFRTL-------LQALETTPGLYFSYETDLTLNLQRRCKLAEGWNRK 163
Query: 172 GLVHRIEYTIDNQ-DQRYVWNYNQISEIVQLRSRIAVQERPYFDSGSFLVFLVRGFCQTI 230
+ + E Q D RYVWN++ + ++++ ++ V + FD L + V
Sbjct: 164 PMWKQAEGLFACQADPRYVWNWHLLEDLIECKT---VLQYMLFDINQGLSYQVAELKLKN 220
Query: 231 TDGISSSCTLISRISTEGMNNLSEFKGIDQSGKVSNFVETEIIVQTRRNVFSYTMTGGDI 290
+ + S ++SR T + +G + G +NFVE+E IV+ FS G I
Sbjct: 221 SPAVVS---IMSRRCTRRLGTRMWRRGANLEGDAANFVESEQIVEINGFKFSLLQVRGSI 277
Query: 291 PLNWELVEGQFLHGKKPKL-LSKASTVQPSFDLHFDELMSKYGVVSIVNVSKPKNDAYEA 349
PL WE + KP+L ++K HF +L +YG + V+++ D E
Sbjct: 278 PLLWEQIVDL---SYKPRLKINKHEETPKVVQRHFHDLCQRYGEIMAVDLTDQHGD--EG 332
Query: 350 MINTYQKCASSKGIDLTLIE-DSTSALNRIPHRIIYLLQQKI-YEF---GSFAYDMDKKI 404
++ K D+ + D + +L ++I EF G F D D+ I
Sbjct: 333 ALSKAYATEMEKLPDVRYVSFDFHQVCGTTNFDNLGVLYEQIGDEFEKQGYFLVDADENI 392
Query: 405 YVGKQTGVFRISAVNLFKKLNIVEKVISADVLELTINELEEKDISSDFWKSHDSLWKSND 464
+ +Q GV R + ++ + N+ + + L L + + D + D K
Sbjct: 393 -LEEQKGVIRSNCIDCLDRTNVTQSFMGQKSLNLQLQRIGVCDSTECISTFEDDYTKFRT 451
Query: 465 FWLER 469
W E+
Sbjct: 452 IWAEQ 456
>ECU10g1370 [U] KOG0565 Inositol polyphosphate 5-phosphatase and related
proteins
Length = 322
Score = 70.5 bits (171), Expect = 1e-11
Identities = 65/215 (30%), Positives = 99/215 (45%), Gaps = 25/215 (11%)
Query: 596 YHAVFNSQLGGLALLVFTDEENKSRIKHIEGDMKKTGFGGISSNKGAIAVHLWLSNTKFC 655
Y V ++ GL +V + E + + + I GF G NKGA + +
Sbjct: 57 YKMVSADRVLGLWSIVLSKERHSTTVMKIG-----LGFLGFI-NKGACVTRI---SNGVM 107
Query: 656 FVVSHLSAGLENVEQRHNDYKSIAKHIRFSKGTRIKDHDGVIWMGDFNFRILLSNDDVRQ 715
F+ HLSA EN ++R + + + + I + +K D V+ GD NFR+ V +
Sbjct: 108 FISCHLSAHQENSKKRQEEIRKVFECICDEES--LKGIDTVVLAGDMNFRV----SGVPR 161
Query: 716 AIIDKNYHRLFEKDQLNQQMISGESFPFFDEMEITFPPTYKFNPGTDVYDTSEKMRIPAW 775
A+ +Y R DQ N+ ++P F E I F PTYK+ GTD + R P+W
Sbjct: 162 AL---DYSRARPGDQCNEFR---RAYPTFLEEVIRFGPTYKYITGTDELC---RKRHPSW 212
Query: 776 TDRI-LSRGEILRQELYGSAEDIVFSDHRPVYGLF 809
DR+ +S R Y S + SDH+PV +F
Sbjct: 213 CDRVFVSSSCTCRFNTYSSIHSVKISDHKPVVCIF 247
>ECU03g1160 [I] KOG1889 Putative phosphoinositide phosphatase
Length = 518
Score = 68.9 bits (167), Expect = 3e-11
Identities = 70/260 (26%), Positives = 116/260 (43%), Gaps = 32/260 (12%)
Query: 214 DSGS-FLVFLVRGFCQTITDGISSSCTLISRISTEGMNNLSEFKGIDQSGKVSNFVETEI 272
D GS F V+ ++GF ++ G + LISR S +G D SG VSN+VETE
Sbjct: 147 DKGSLFSVWCIQGFFGSVDIG-TVCLRLISRRSWRRAGARYFSRGSDASGYVSNYVETEQ 205
Query: 273 IVQTRRNVFSYTMTGGDIPLNWELVEGQFLHGKKPKLLSKASTVQPSFDLHFDE--LMSK 330
I+ S+ G IPL WE V G+ + PK++ + LH + L K
Sbjct: 206 IIYDGEKTVSHLQVRGSIPLIWEHVLGREYN---PKIVVSDRKI-----LHIADKVLRDK 257
Query: 331 YGVVSIVNVSKPKNDAYEAMIN-TYQK---CASSKGIDLTLIEDSTSALNRIPHRIIYLL 386
YG V +N+ +N YE M++ Y+K + +G+ ++ + + L+
Sbjct: 258 YGDVFYLNLI--RNSGYEGMLHCAYEKELLGNNKEGVHFNFFKEGGILEGDTRKKFLGLV 315
Query: 387 QQKIYEFGSFAYDMDKKIYVGK---QTGVFRISAVNLFKKLNIVEKVISADVLELTINEL 443
+Q + FG Y G Q+GV R + ++ + NI + ++ +LE ++
Sbjct: 316 EQALLSFG----------YHGPGSLQSGVIRTNCIDCLDRTNISQFIMGEIILEKQLSHF 365
Query: 444 EEKDISSDFWKSHDSLWKSN 463
+ +D F + LW N
Sbjct: 366 DIED-KKHFCEQAKCLWYDN 384
>CE09807 [I] KOG1889 Putative phosphoinositide phosphatase
Length = 591
Score = 68.6 bits (166), Expect = 4e-11
Identities = 103/462 (22%), Positives = 192/462 (41%), Gaps = 55/462 (11%)
Query: 101 VIEEETIYQILNINFYCIDSD-----KYDSMFQDLSDIGYERQLTEHPCGHLKMLISDGS 155
+ + I Q+ N N + I K ++ I Y R T+ L ++S G
Sbjct: 80 ITKASLIGQVNNHNIWTIQDAEIIPYKKTTLHLTEKQIRYNRLFTDM----LTHVLSIGG 135
Query: 156 FYYSNDFDITNS---LQERGL-VHRIEYTIDNQDQRYVWNYNQISEIVQLRSRIAVQERP 211
FYYS DI+ + LQE + + + +D +R++WN + +S+I Q+ ER
Sbjct: 136 FYYSTTLDISRTFQWLQENAVPLFKTRSMLDRASERFIWNGHLLSQIRQVPGA----ER- 190
Query: 212 YFDSGSFLVFLVRGFC---QTITDGISSSCTLISRISTEGMNNLSEFKGIDQSGKVSNFV 268
+ + ++ GF + +G T+ISR S +G+D G +NFV
Sbjct: 191 ------YTLPVIHGFIGQNRVNVNGKEIKLTIISRRSIYRAGVRFYKRGVDVDGHAANFV 244
Query: 269 ETEIIVQ---TRRNVFSYTMTGGDIPLNWEL---VEGQFLHGKKPKLLSKASTVQPSFDL 322
ETE IV+ +++ S+ G IPL W + Q + KP + + +F
Sbjct: 245 ETEQIVEYTNPDKHLTSFVQLRGSIPLLWTQKPNLRWQPMPTLKP-TDDQLAAFNRAFSW 303
Query: 323 HFDELMSKYGVVSIVNVSKPKNDAYEAMINTYQKCASSKGIDLTLIEDSTSALNRIPHRI 382
H K+ +V++VN K + + + A+ + + + + HRI
Sbjct: 304 HKQHYGGKHVIVNLVN-QKGREKKVGGELERISRQANIEFVRYHQFDFHKECHSMQWHRI 362
Query: 383 IYL---LQQKIYEFGSFAYDMDKKIYVGKQTGVFRISAVNLFKKLNIVEKVISAD----- 434
L L Q+I FG F + Q G FR + ++ + N+V+ +++ +
Sbjct: 363 DLLREQLSQEISSFGYFYLSPNSMETSRFQRGFFRTNCMDCLDRTNVVQSMLARESLTEQ 422
Query: 435 --VLELTINELEEKDIS--SDFWKSHDSLWKSNDFWLERLNSKHSKNPSKYKKIYRGLFD 490
+L + +E + +DI D +K +W N R + + + + R +
Sbjct: 423 LRMLGILYSEQKVQDIPLLEDAFK---QMWADNGDECSRQYAGTGALKADFTRHGRRTY- 478
Query: 491 PSAIVALYDPLHIYVTRFLRQRRHEYTFEKEISIFAGTFNVN 532
+ A+ D ++ V+R++R + + I +F G F V+
Sbjct: 479 ---VGAMKDGVNA-VSRYVRNNFGDGYRQDSIDLFLGNFLVD 516
>ECU08g1420 [U] KOG0566 Inositol-145-triphosphate 5-phosphatase (synaptojanin)
INP51/INP52/INP53 family
Length = 453
Score = 58.9 bits (141), Expect = 4e-08
Identities = 53/197 (26%), Positives = 94/197 (46%), Gaps = 27/197 (13%)
Query: 240 LISRISTEGMNNLSEFKGIDQSGKVSNFVETEIIVQTRRN---VFSYTMTGGDIPLNWEL 296
L+S +S+ + +GID+ G S FV+T QT+RN +F +T+ G +P+ W
Sbjct: 183 LLSLVSSNRVGTRYLCRGIDEEGNASLFVKTHF--QTKRNNSTIFDFTIIRGSVPIFWS- 239
Query: 297 VEGQFLHG--KKPKLLSKASTVQPSFDLHFDELMSKYGVVSIVNVSKPKNDAYEAMINTY 354
Q HG K + + V+ +F HF +L +YG + ++N+ K YE + ++
Sbjct: 240 ---QRGHGIPAKVNIYGEDGAVKKAFAKHFKKLRREYGKIYVINLLGEKK--YEKQLTSH 294
Query: 355 QKCASSKGIDLTLIEDSTSALNRIPHRIIYLLQQKIYEFGSFAYDMDKKIYVGKQTGVFR 414
S+ +DL I +T LN H Y + + F K +G+Q VFR
Sbjct: 295 ----FSRLLDLENIPYTTFDLN--AHASNYDDLKFLLYF--------KLQGIGQQDIVFR 340
Query: 415 ISAVNLFKKLNIVEKVI 431
++ ++ + N+ + +I
Sbjct: 341 VNCLDCLDRTNVAQSLI 357
>At5g66020 [I] KOG1889 Putative phosphoinositide phosphatase
Length = 549
Score = 58.5 bits (140), Expect = 5e-08
Identities = 79/378 (20%), Positives = 158/378 (40%), Gaps = 42/378 (11%)
Query: 101 VIEEETIYQILNINFYCIDSDKYDSMFQDLSDIGYERQLTEHPCGHLKMLISDGS--FYY 158
V E E++ L Y I+S K+ L + E++ E + +++ + Y+
Sbjct: 80 VTESESVGSFLGHPIYKINSLKFLPCDHSLENPHEEQKKMETDDYSRLLSVAERTTGLYF 139
Query: 159 SNDFDIT---NSLQERGLVHRIEYTIDNQDQRYVWNYNQISEIVQLRSRIAVQERPYFDS 215
S + ++T L + G ++ + R++WN + ++ +
Sbjct: 140 SYEINLTLTAQRLHDLGDESKLLPLWRQAEPRFLWNNYMLEVLIDNKL------------ 187
Query: 216 GSFLVFLVRGFCQTITDGISSSCTLISRISTEGMNNLSEFKGIDQSGKVSNFVETEIIVQ 275
FL+ +++G I D TLI+R + +G D G V+NFVETE IV+
Sbjct: 188 DQFLLPVIQG---NIVD-----ITLIARRCSRRNGTRMWRRGADPDGYVANFVETEQIVR 239
Query: 276 TRRNVFSYTMTGGDIPLNWELVEGQFLHGKKPKLLSKASTVQPSFDLHFDELMSKYGVVS 335
S+ G +P WE + + K +++ V+ + + HF +L KYG V
Sbjct: 240 MNGYTSSFVQIRGSMPFMWEQIV-DLTYKPKFEIVQPEEAVRIA-ERHFLDLRKKYGSVL 297
Query: 336 IVNVSKPKNDAYEAMINTYQKCASSKGIDLTLIEDSTSALNRIPHRIIYLLQQKIYEF-- 393
V++ + E Q +S+ + D I + +L +++ +F
Sbjct: 298 AVDLHGGEGRLSERFAGAMQHITASRYLHF----DFHHICGHIHFERLAILYEQMEDFLE 353
Query: 394 --GSFAYDMDKKIYVGKQTGVFRISAVNLFKKLNIVEKVISADVLELTINEL----EEKD 447
G F + +K + +Q G+ R + ++ + N+ + +I +LEL + + E+
Sbjct: 354 KNGYFLLN-EKGEKMKEQLGIVRTNCIDCLDRTNVTQSMIGRKLLELQLKRIGVFGAEET 412
Query: 448 ISS--DFWKSHDSLWKSN 463
I S +F + + LW ++
Sbjct: 413 IRSHQNFDECYKILWANH 430
>CE20170 [I] KOG1890 Phosphoinositide phosphatase SAC1
Length = 783
Score = 57.8 bits (138), Expect = 8e-08
Identities = 69/304 (22%), Positives = 127/304 (41%), Gaps = 34/304 (11%)
Query: 147 LKMLISDGSFYYSNDFDITNSLQERGLVHRIEYTIDNQDQRYVWNYNQISEIVQLRSRIA 206
LK+ FY+ D+T S Q+ R +T ++ + WN + + + +
Sbjct: 146 LKLFNDSKDFYFCRSRDVTISSQKY-FEKREAHTSEDS---FFWNKRMVGNLGEAKI--- 198
Query: 207 VQERPYFDSGSFLVFLVRGFCQT----ITDGISS--SCTLISRISTEGMNNLSEFKGIDQ 260
S F +++G+ T ITD I++ + T+ISR ST +GID+
Sbjct: 199 --------SDKFTCPIMQGYVATSQLEITDQINAYLTITIISRRSTRRAGARYLRRGIDE 250
Query: 261 SGKVSNFVETEIIVQTRRNVFSYTMTGGDIPLNWELVEGQFLHGKKPKLLSKASTVQPS- 319
+ V+NFVETE+I+ + S+ G IP+ W ++ +P L+ S +
Sbjct: 251 ASNVANFVETELILNIFEHELSFVQCRGSIPVFWSQRGFKY----RPPLIINRSVEETHG 306
Query: 320 -FDLHFDELMSKYGVVSI-VNVSKPKNDAYEAMINTYQKCASSKGIDLTL----IEDSTS 373
F HF L + Y + V++ + + C + D+T +
Sbjct: 307 VFTEHFKRLKAHYDTPLVAVSLVDQRGRELPLAQRFLEHCVKADDNDVTFFSFDLHQHCR 366
Query: 374 ALN-RIPHRIIYLLQQKIYEFGSFAYDMDKKIYVGKQTGVFRISAVNLFKKLNIVEKVIS 432
LN + +I +++ + G D ++ V Q GV R + ++ + N+V+ IS
Sbjct: 367 GLNFQKLQTLISSMEETLKTIGFCWVDKTGEV-VQSQKGVVRTNCIDCLDRTNLVQGQIS 425
Query: 433 ADVL 436
V+
Sbjct: 426 LFVV 429
>YNL325c [I] KOG1888 Putative phosphoinositide phosphatase
Length = 879
Score = 57.0 bits (136), Expect = 1e-07
Identities = 66/222 (29%), Positives = 94/222 (41%), Gaps = 47/222 (21%)
Query: 155 SFYYSNDFDITNSLQERGL------VHRIEYT----IDNQDQRYVWNYNQISEIVQLRSR 204
+FY+S +DITN+LQ L V R + T I + ++ +VWN N +S I
Sbjct: 174 TFYFSYTYDITNTLQTNILREKLKAVDRCDITIPCGITDYNEMFVWNNNLLSPIFACIDT 233
Query: 205 IAVQERPYFDSGSFLVFLVRGFCQTITD---GISSSCTLISRISTEGMNNLSEFKGIDQS 261
+ FD + ++ GF + G S TLI+R S +G++
Sbjct: 234 V-------FD---WFQCIIHGFIDQVNVSVLGKSIYITLIARRSHHFAGARFLKRGVNNK 283
Query: 262 GKVSNFVETEIIV---------QTRRNVF------SYTMTGGDIPLNWELVEGQFLHGKK 306
G V+N VETE IV Q F S+ G IPL W + L K
Sbjct: 284 GHVANEVETEQIVTDMILTPFHQPGNGFFDSDRYTSFVQHRGSIPLYW-TQDASNLTTKP 342
Query: 307 PKLLSKASTVQPSFD---LHFDELMSKY--GVVSIVNVSKPK 343
P + + V P F LHFD L +Y G + I+N+ K K
Sbjct: 343 P---IRINVVDPFFSPAALHFDNLFQRYGGGTIQILNLIKTK 381
>Hs22066542 [U] KOG0565 Inositol polyphosphate 5-phosphatase and related
proteins
Length = 254
Score = 53.5 bits (127), Expect = 1e-06
Identities = 30/75 (40%), Positives = 43/75 (57%), Gaps = 1/75 (1%)
Query: 696 VIWMGDFNFRIL-LSNDDVRQAIIDKNYHRLFEKDQLNQQMISGESFPFFDEMEITFPPT 754
+IW GD NFRI VR++I ++ Y L+EKDQL+ F E + FPPT
Sbjct: 128 IIWFGDMNFRIEDFGLHFVRESIKNRCYGGLWEKDQLSIAKKHDPLLREFQEGRLLFPPT 187
Query: 755 YKFNPGTDVYDTSEK 769
YKF+ ++ YDT ++
Sbjct: 188 YKFDRNSNDYDTRKQ 202
>At1g17340 [I] KOG1888 Putative phosphoinositide phosphatase
Length = 802
Score = 52.8 bits (125), Expect = 3e-06
Identities = 64/288 (22%), Positives = 113/288 (39%), Gaps = 41/288 (14%)
Query: 62 TTFTALFGLITVKGQVFIGIITSNKKVGSPRWKLNEQDKVIEEETIYQILNINFYCIDSD 121
TT + G + ++ +IT KKVG I T+Y I I
Sbjct: 101 TTCYGIIGFVRFLEPYYMLLITKRKKVGE-----------ICGHTVYGIAESQMIAIPHP 149
Query: 122 KYDS-MFQDLSDIGYERQLTEHPCGHLKMLISDGSFYYSNDFDITNSLQERGLVHRIEYT 180
S + + +++ Y++ L+ ++ +FY+S + + SLQ+ + E
Sbjct: 150 SIQSKVAKSEAELRYKKLLS--------VVDLSKNFYFSYTYHLMYSLQKN--IGNTERG 199
Query: 181 IDNQDQRYVWNYNQISEIVQLRSRIAVQERPYFDSGSFLVFLVRGFCQTITDGISSSCTL 240
+ + +VWN EI R + + V L+ GF Q +S +
Sbjct: 200 NPHDNTMFVWNSFLTREI-----------RKILQNSIWTVALIYGFFQQTKCSVSGEKFV 248
Query: 241 ISRISTEGMNNLSEFKGIDQSGKVSNFVETEIIVQ------TRRNVFSYTMTGGDIPLNW 294
+ I+ + +G++ G+V+N VETE IV + + S G IPL W
Sbjct: 249 FTIIARRSRHYAGTRRGVNDIGRVANDVETEQIVSKVVPAGQKIPITSVVQVRGSIPLFW 308
Query: 295 ELVEGQFLHGKKPKLLSKASTVQPSFDLHFDELMSKYG-VVSIVNVSK 341
E + + +L+K + HF L +YG + I+N+ K
Sbjct: 309 S-QEASVFNPQPEIILNKKDANYEATQHHFQNLRQRYGNRIIILNLLK 355
Database: KOG eukaryal database 04/03
Posted date: Apr 14, 2003 1:07 PM
Number of letters in database: 30,389,216
Number of sequences in database: 60,738
Lambda K H
0.317 0.135 0.391
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 55,902,661
Number of Sequences: 60738
Number of extensions: 2446344
Number of successful extensions: 5958
Number of sequences better than 1.0e-05: 60
Number of HSP's better than 0.0 without gapping: 36
Number of HSP's successfully gapped in prelim test: 24
Number of HSP's that attempted gapping in prelim test: 5676
Number of HSP's gapped (non-prelim): 89
length of query: 941
length of database: 30,389,216
effective HSP length: 116
effective length of query: 825
effective length of database: 23,343,608
effective search space: 19258476600
effective search space used: 19258476600
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)