ORF STATUS Function Best COG Functional category Pathways and functional systems
r_klactIV3719 check: MH R KOG0605 General function prediction only NDR and related serine/threonine kinases
Only best alignment is shown:
BLASTP 2.2.3 [May-13-2002]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= r_klactIV3719 1256065 1257765 567
(567 letters)
Database: KOG eukaryal database 04/03
60,738 sequences; 30,389,216 total letters
Searching..................................................done
Color Key for Alignment Scores: 
Score E
Sequences producing significant alignments: (bits) Value
YGR092w [R] KOG0605 NDR and related serine/threonine kinases 759 0.0
YPR111w [R] KOG0605 NDR and related serine/threonine kinases 739 0.0
SPAC24B11.11c [R] KOG0605 NDR and related serine/threonine kinases 440 e-123
SPCC417.06c [R] KOG0605 NDR and related serine/threonine kinases 348 1e-95
Hs18579683 [R] KOG0605 NDR and related serine/threonine kinases 232 1e-60
SPAC821.12 [R] KOG0605 NDR and related serine/threonine kinases 228 2e-59
Hs6005814 [R] KOG0605 NDR and related serine/threonine kinases 227 3e-59
CE28760 [R] KOG0605 NDR and related serine/threonine kinases 226 7e-59
7293735 [R] KOG0605 NDR and related serine/threonine kinases 226 9e-59
YNL161w [R] KOG0605 NDR and related serine/threonine kinases 224 4e-58
7301980 [D] KOG0608 Warts/lats-like serine threonine kinases 221 2e-57
At5g09890 [R] KOG0605 NDR and related serine/threonine kinases 211 2e-54
CE13844 [D] KOG0608 Warts/lats-like serine threonine kinases 209 1e-53
Hs4758666 [D] KOG0608 Warts/lats-like serine threonine kinases 205 1e-52
Hs18959200 [D] KOG0608 Warts/lats-like serine threonine kinases 204 3e-52
At3g23310 [R] KOG0605 NDR and related serine/threonine kinases 204 4e-52
At4g33080 [R] KOG0605 NDR and related serine/threonine kinases 203 6e-52
At1g30640 [R] KOG0605 NDR and related serine/threonine kinases 202 8e-52
At2g20470 [R] KOG0605 NDR and related serine/threonine kinases 201 2e-51
At1g03920 [R] KOG0605 NDR and related serine/threonine kinases 196 6e-50
At4g14350 [R] KOG0605 NDR and related serine/threonine kinases 195 1e-49
At2g19400 [R] KOG0605 NDR and related serine/threonine kinases 192 1e-48
At1g48490 [TR] KOG0606 Microtubule-associated serine/threonine k... 177 4e-44
At3g17850 [TR] KOG0606 Microtubule-associated serine/threonine k... 174 3e-43
7294566 [T] KOG0612 Rho-associated coiled-coil containing protei... 172 2e-42
At5g62310 [TR] KOG0606 Microtubule-associated serine/threonine k... 169 8e-42
At1g45160 [TR] KOG0606 Microtubule-associated serine/threonine k... 167 4e-41
Hs20543401 [TR] KOG0606 Microtubule-associated serine/threonine ... 167 5e-41
Hs4885583 [T] KOG0612 Rho-associated coiled-coil containing prot... 164 3e-40
Hs4505831 [T] KOG0612 Rho-associated coiled-coil containing prot... 162 1e-39
Hs17455844 [TR] KOG0606 Microtubule-associated serine/threonine ... 161 2e-39
Hs14149671 [TR] KOG0606 Microtubule-associated serine/threonine ... 159 8e-39
CE08098 [T] KOG0612 Rho-associated coiled-coil containing protei... 159 8e-39
7294265 [TR] KOG0606 Microtubule-associated serine/threonine kin... 159 1e-38
CE11916 [T] KOG0612 Rho-associated coiled-coil containing protei... 157 3e-38
7291742_1 [T] KOG0612 Rho-associated coiled-coil containing prot... 157 4e-38
Hs16357474_1 [T] KOG0612 Rho-associated coiled-coil containing p... 156 7e-38
Hs4759050 [T] KOG0603 Ribosomal protein S6 kinase 156 9e-38
YNR047w [R] KOG0610 Putative serine/threonine protein kinase 155 2e-37
CE20493 [TR] KOG0606 Microtubule-associated serine/threonine kin... 154 3e-37
Hs10334852 [T] KOG0612 Rho-associated coiled-coil containing pro... 153 6e-37
Hs20536595 [T] KOG0612 Rho-associated coiled-coil containing pro... 151 2e-36
Hs4759044 [T] KOG0612 Rho-associated coiled-coil containing prot... 150 5e-36
YCR091w [R] KOG0610 Putative serine/threonine protein kinase 149 8e-36
Hs7657526 [T] KOG0603 Ribosomal protein S6 kinase 149 1e-35
SPAC22E12.14c [RT] KOG0598 Ribosomal protein S6 kinase and relat... 147 3e-35
Hs20149547 [T] KOG0603 Ribosomal protein S6 kinase 145 1e-34
CE18169 [T] KOG0603 Ribosomal protein S6 kinase 145 1e-34
7293249 [T] KOG0612 Rho-associated coiled-coil containing protei... 145 2e-34
CE13014 [T] KOG0603 Ribosomal protein S6 kinase 144 3e-34
CE04603 [T] KOG0616 cAMP-dependent protein kinase catalytic subu... 144 3e-34
YMR104c [RT] KOG0598 Ribosomal protein S6 kinase and related pro... 144 4e-34
ECU01g1320 [T] KOG0612 Rho-associated coiled-coil containing pro... 144 4e-34
Hs19923570 [T] KOG0603 Ribosomal protein S6 kinase 144 5e-34
SPCC24B10.07 [RT] KOG0598 Ribosomal protein S6 kinase and relate... 143 6e-34
CE27166 [T] KOG0616 cAMP-dependent protein kinase catalytic subu... 142 1e-33
Hs20127541 [RT] KOG0598 Ribosomal protein S6 kinase and related ... 141 2e-33
YKL126w [RT] KOG0598 Ribosomal protein S6 kinase and related pro... 140 5e-33
SPCC4G3.08 [RT] KOG0598 Ribosomal protein S6 kinase and related ... 140 5e-33
Hs5032091 [RT] KOG0598 Ribosomal protein S6 kinase and related p... 140 5e-33
YKL166c [T] KOG0616 cAMP-dependent protein kinase catalytic subu... 140 7e-33
Hs4506057 [T] KOG0616 cAMP-dependent protein kinase catalytic su... 140 7e-33
7297542 [T] KOG0616 cAMP-dependent protein kinase catalytic subu... 140 7e-33
Hs20070247_2 [RT] KOG0598 Ribosomal protein S6 kinase and relate... 139 9e-33
Hs4506055 [T] KOG0616 cAMP-dependent protein kinase catalytic su... 139 1e-32
Hs5453972 [T] KOG0694 Serine/threonine protein kinase 138 3e-32
YJL164c [T] KOG0616 cAMP-dependent protein kinase catalytic subu... 137 4e-32
CE14798 [RT] KOG0598 Ribosomal protein S6 kinase and related pro... 136 7e-32
At3g08720 [RT] KOG0598 Ribosomal protein S6 kinase and related p... 135 1e-31
Hs15619015 [T] KOG0616 cAMP-dependent protein kinase catalytic s... 135 2e-31
CE22045 [RT] KOG0598 Ribosomal protein S6 kinase and related pro... 135 2e-31
7295638 [T] KOG0603 Ribosomal protein S6 kinase 135 2e-31
SPBC1861.09 [R] KOG0610 Putative serine/threonine protein kinase 134 3e-31
YHR205w [RT] KOG0598 Ribosomal protein S6 kinase and related pro... 134 5e-31
Hs4826948 [T] KOG0616 cAMP-dependent protein kinase catalytic su... 134 5e-31
CE28744 [RT] KOG0598 Ribosomal protein S6 kinase and related pro... 133 6e-31
At3g08730 [RT] KOG0598 Ribosomal protein S6 kinase and related p... 133 6e-31
Hs5453970 [T] KOG0694 Serine/threonine protein kinase 132 1e-30
Hs4506737 [RT] KOG0598 Ribosomal protein S6 kinase and related p... 132 1e-30
Hs14735945 [T] KOG0694 Serine/threonine protein kinase 132 1e-30
7303111 [T] KOG0695 Serine/threonine protein kinase 132 1e-30
SPAC1B9.02c [RT] KOG0598 Ribosomal protein S6 kinase and related... 132 2e-30
CE15473 [T] KOG0616 cAMP-dependent protein kinase catalytic subu... 131 2e-30
At3g20830 [R] KOG0610 Putative serine/threonine protein kinase 131 2e-30
YPL203w [T] KOG0616 cAMP-dependent protein kinase catalytic subu... 130 7e-30
Hs4885549 [T] KOG0690 Serine/threonine protein kinase 129 1e-29
CE05274 [T] KOG0690 Serine/threonine protein kinase 129 2e-29
Hs4506739 [RT] KOG0598 Ribosomal protein S6 kinase and related p... 128 3e-29
CE15612 [T] KOG0690 Serine/threonine protein kinase 127 5e-29
7295426 [RT] KOG0598 Ribosomal protein S6 kinase and related pro... 127 5e-29
Hs4885563 [T] KOG0694 Serine/threonine protein kinase 126 1e-28
CE18646 [T] KOG0690 Serine/threonine protein kinase 126 1e-28
Hs20535816 [T] KOG0695 Serine/threonine protein kinase 125 2e-28
Hs10864650 [T] KOG0695 Serine/threonine protein kinase 125 2e-28
CE29298 [T] KOG0690 Serine/threonine protein kinase 125 2e-28
CE02604 [T] KOG0695 Serine/threonine protein kinase 125 2e-28
7301734 [T] KOG0694 Serine/threonine protein kinase 125 2e-28
SPAC4G8.05 [R] KOG0610 Putative serine/threonine protein kinase 125 2e-28
Hs4506071 [T] KOG0695 Serine/threonine protein kinase 125 2e-28
Hs4506735 [T] KOG0603 Ribosomal protein S6 kinase 124 4e-28
7300106 [T] KOG0690 Serine/threonine protein kinase 124 4e-28
CE29092 [T] KOG0694 Serine/threonine protein kinase 124 5e-28
Hs10835242 [T] KOG0614 cGMP-dependent protein kinase 123 6e-28
Hs5453974 [T] KOG0694 Serine/threonine protein kinase 123 8e-28
Hs4502023 [T] KOG0690 Serine/threonine protein kinase 123 8e-28
At3g10540 [T] KOG0592 3-phosphoinositide-dependent protein kinas... 122 1e-27
CE19898 [T] KOG0614 cGMP-dependent protein kinase 122 1e-27
CE19897 [T] KOG0614 cGMP-dependent protein kinase 122 1e-27
Hs5453976 [T] KOG0694 Serine/threonine protein kinase 120 6e-27
At1g51170 [R] KOG0610 Putative serine/threonine protein kinase 120 6e-27
7294770 [T] KOG0603 Ribosomal protein S6 kinase 120 6e-27
7301971 [T] KOG0616 cAMP-dependent protein kinase catalytic subu... 119 9e-27
CE15475 [T] KOG0616 cAMP-dependent protein kinase catalytic subu... 119 1e-26
YBR028c [RT] KOG0598 Ribosomal protein S6 kinase and related pro... 119 2e-26
SPBC725.06c [R] KOG0605 NDR and related serine/threonine kinases 119 2e-26
At5g04510 [T] KOG0592 3-phosphoinositide-dependent protein kinas... 119 2e-26
At5g03640 [R] KOG0610 Putative serine/threonine protein kinase 119 2e-26
7300437 [TR] KOG0606 Microtubule-associated serine/threonine kin... 119 2e-26
YOL100w [T] KOG0592 3-phosphoinositide-dependent protein kinase ... 118 2e-26
7296166 [T] KOG0614 cGMP-dependent protein kinase 118 2e-26
YBL105c [T] KOG0694 Serine/threonine protein kinase 118 3e-26
Hs5453978 [T] KOG0614 cGMP-dependent protein kinase 117 4e-26
CE05507 [T] KOG0603 Ribosomal protein S6 kinase 117 5e-26
Hs4759052 [T] KOG0603 Ribosomal protein S6 kinase 117 6e-26
Hs4885061 [T] KOG0690 Serine/threonine protein kinase 116 8e-26
Hs4885347 [T] KOG0986 G protein-coupled receptor kinase 115 1e-25
Hs10835065 [T] KOG0616 cAMP-dependent protein kinase catalytic s... 115 1e-25
CE17354 [T] KOG0694 Serine/threonine protein kinase 115 2e-25
CE17353 [T] KOG0694 Serine/threonine protein kinase 115 2e-25
At3g27580 [R] KOG0610 Putative serine/threonine protein kinase 115 2e-25
At2g36350 [R] KOG0610 Putative serine/threonine protein kinase 115 2e-25
CE02586 [T] KOG0696 Serine/threonine protein kinase 114 3e-25
7303915 [T] KOG0694 Serine/threonine protein kinase 114 3e-25
7303914 [T] KOG0694 Serine/threonine protein kinase 114 3e-25
At2g44830 [R] KOG0610 Putative serine/threonine protein kinase 114 4e-25
7302861 [T] KOG0696 Serine/threonine protein kinase 114 4e-25
YDR490c [T] KOG0592 3-phosphoinositide-dependent protein kinase ... 114 5e-25
Hs4506073 [T] KOG0694 Serine/threonine protein kinase 112 1e-24
Hs14758219 [T] KOG0694 Serine/threonine protein kinase 112 1e-24
7302860 [T] KOG0696 Serine/threonine protein kinase 112 1e-24
Hs4885349 [T] KOG0986 G protein-coupled receptor kinase 112 2e-24
At3g44610 [R] KOG0610 Putative serine/threonine protein kinase 112 2e-24
SPBC106.10 [T] KOG0616 cAMP-dependent protein kinase catalytic s... 111 3e-24
At5g40030 [R] KOG0610 Putative serine/threonine protein kinase 111 3e-24
At4g26610 [R] KOG0610 Putative serine/threonine protein kinase 111 3e-24
YMR001c [D] KOG0575 Polo-like serine/threonine protein kinase 109 1e-23
YDR466w [T] KOG0592 3-phosphoinositide-dependent protein kinase ... 109 1e-23
Hs4506067 [T] KOG0696 Serine/threonine protein kinase 109 1e-23
Hs13384594 [T] KOG0696 Serine/threonine protein kinase 109 1e-23
Hs4504101 [T] KOG0986 G protein-coupled receptor kinase 108 2e-23
At5g55910 [R] KOG0610 Putative serine/threonine protein kinase 108 2e-23
Hs7019489 [T] KOG0694 Serine/threonine protein kinase 108 2e-23
At5g47750 [R] KOG0610 Putative serine/threonine protein kinase 108 2e-23
At4g13000 [R] KOG0610 Putative serine/threonine protein kinase 107 4e-23
7302050 [T] KOG0986 G protein-coupled receptor kinase 107 5e-23
SPBC12D12.04c [T] KOG0694 Serine/threonine protein kinase 106 8e-23
At3g25250 [R] KOG0610 Putative serine/threonine protein kinase 106 8e-23
At3g14370 [R] KOG0610 Putative serine/threonine protein kinase 106 8e-23
At1g53700 [R] KOG0610 Putative serine/threonine protein kinase 106 8e-23
Hs8923754 [RT] KOG0598 Ribosomal protein S6 kinase and related p... 105 2e-22
Hs21166359 [T] KOG0986 G protein-coupled receptor kinase 105 2e-22
At2g34650 [R] KOG0610 Putative serine/threonine protein kinase 105 2e-22
At2g26700_2 [R] KOG0610 Putative serine/threonine protein kinase 104 3e-22
CE03979 [T] KOG0614 cGMP-dependent protein kinase 104 4e-22
YFL033c [R] KOG0605 NDR and related serine/threonine kinases 103 7e-22
Hs4506529 [T] KOG0986 G protein-coupled receptor kinase 103 7e-22
At3g12690 [R] KOG0610 Putative serine/threonine protein kinase 103 7e-22
SPBC4C3.11 [T] KOG0592 3-phosphoinositide-dependent protein kina... 103 9e-22
At5g35410 [T] KOG0583 Serine/threonine protein kinase 103 9e-22
At1g79250 [R] KOG0610 Putative serine/threonine protein kinase 103 9e-22
Hs22068916 [T] KOG0696 Serine/threonine protein kinase 102 2e-21
Hs20127450 [T] KOG0696 Serine/threonine protein kinase 102 2e-21
7291910 [T] KOG0592 3-phosphoinositide-dependent protein kinase ... 102 2e-21
Hs4501971 [T] KOG0986 G protein-coupled receptor kinase 101 3e-21
CE18699 [T] KOG0694 Serine/threonine protein kinase 100 6e-21
Hs4505695 [T] KOG0592 3-phosphoinositide-dependent protein kinas... 100 8e-21
At1g16440 [R] KOG0610 Putative serine/threonine protein kinase 100 8e-21
CE28739 [T] KOG0592 3-phosphoinositide-dependent protein kinase ... 99 2e-20
CE02074 [T] KOG0986 G protein-coupled receptor kinase 99 2e-20
7297611 [T] KOG0614 cGMP-dependent protein kinase 99 2e-20
Hs14249562 [TR] KOG0606 Microtubule-associated serine/threonine ... 97 9e-20
CE03492 [RT] KOG0598 Ribosomal protein S6 kinase and related pro... 96 1e-19
At1g29230 [T] KOG0583 Serine/threonine protein kinase 96 1e-19
Hs22042851 [T] KOG0986 G protein-coupled receptor kinase 96 1e-19
At5g01810 [T] KOG0583 Serine/threonine protein kinase 96 2e-19
At2g26980 [T] KOG0583 Serine/threonine protein kinase 96 2e-19
At2g25090 [T] KOG0583 Serine/threonine protein kinase 96 2e-19
CE28740 [T] KOG0592 3-phosphoinositide-dependent protein kinase ... 95 2e-19
CE22877 [D] KOG0575 Polo-like serine/threonine protein kinase 95 3e-19
At5g45820 [T] KOG0583 Serine/threonine protein kinase 95 3e-19
At4g30960 [T] KOG0583 Serine/threonine protein kinase 95 3e-19
At4g24400 [T] KOG0583 Serine/threonine protein kinase 95 3e-19
At4g18700 [T] KOG0583 Serine/threonine protein kinase 95 3e-19
SPAC17G8.14c [T] KOG0694 Serine/threonine protein kinase 94 4e-19
Hs4885055 [T] KOG0986 G protein-coupled receptor kinase 94 6e-19
At1g30270 [T] KOG0583 Serine/threonine protein kinase 94 6e-19
7301972 [T] KOG0616 cAMP-dependent protein kinase catalytic subu... 94 6e-19
CE07285 [D] KOG0575 Polo-like serine/threonine protein kinase 94 7e-19
At2g34180 [T] KOG0583 Serine/threonine protein kinase 92 2e-18
SPCC1450.11c [R] KOG0605 NDR and related serine/threonine kinases 92 3e-18
At5g45810 [T] KOG0583 Serine/threonine protein kinase 92 3e-18
At5g25110 [T] KOG0583 Serine/threonine protein kinase 92 3e-18
Hs14776113 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase ... 91 4e-18
SPCC576.15c [T] KOG0592 3-phosphoinositide-dependent protein kin... 91 6e-18
SPCC18B5.11c [D] KOG0615 Serine/threonine protein kinase Chk2 an... 91 6e-18
At2g45490 [D] KOG0580 Serine/threonine protein kinase 90 8e-18
At2g30360 [T] KOG0583 Serine/threonine protein kinase 90 1e-17
YPL153c [D] KOG0615 Serine/threonine protein kinase Chk2 and rel... 89 1e-17
Hs6005850 [D] KOG0615 Serine/threonine protein kinase Chk2 and r... 89 1e-17
CE20142 [T] KOG0592 3-phosphoinositide-dependent protein kinase ... 89 2e-17
CE01554 [T] KOG0986 G protein-coupled receptor kinase 89 2e-17
At1g49180_1 [OUT] KOG0595 Serine/threonine-protein kinase involv... 89 2e-17
Hs9966875 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 88 3e-17
Hs4507275 [D] KOG0580 Serine/threonine protein kinase 88 3e-17
CE03584 [T] KOG0607 MAP kinase-interacting kinase and related se... 88 3e-17
Hs4507273 [D] KOG0580 Serine/threonine protein kinase 88 4e-17
7297776 [D] KOG0580 Serine/threonine protein kinase 88 4e-17
At5g10930 [T] KOG0583 Serine/threonine protein kinase 87 7e-17
CE29020 [T] KOG0660 Mitogen-activated protein kinase 87 9e-17
At1g01140 [T] KOG0583 Serine/threonine protein kinase 87 9e-17
Hs22066167 [RT] KOG0598 Ribosomal protein S6 kinase and related ... 86 1e-16
Hs14916455 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase ... 86 1e-16
CE17284 [T] KOG0583 Serine/threonine protein kinase 86 1e-16
7298652 [D] KOG0615 Serine/threonine protein kinase Chk2 and rel... 86 1e-16
7293666 [D] KOG0575 Polo-like serine/threonine protein kinase 86 1e-16
Hs5730055 [D] KOG0575 Polo-like serine/threonine protein kinase 86 2e-16
Hs14754789 [OUT] KOG0595 Serine/threonine-protein kinase involve... 86 2e-16
CE24761 [D] KOG0580 Serine/threonine protein kinase 86 2e-16
YPL150w [T] KOG0583 Serine/threonine protein kinase 85 3e-16
HsM4507279 [D] KOG0580 Serine/threonine protein kinase 85 3e-16
At3g17510 [T] KOG0583 Serine/threonine protein kinase 85 3e-16
At3g01090 [T] KOG0583 Serine/threonine protein kinase 85 3e-16
Hs7657214 [T] KOG0583 Serine/threonine protein kinase 84 4e-16
At3g23000 [T] KOG0583 Serine/threonine protein kinase 84 4e-16
7299536 [D] KOG0580 Serine/threonine protein kinase 84 4e-16
YPL209c [D] KOG0580 Serine/threonine protein kinase 84 6e-16
SPCC1259.13 [D] KOG0590 Checkpoint kinase and related serine/thr... 84 6e-16
Hs4758016 [D] KOG0575 Polo-like serine/threonine protein kinase 84 6e-16
Hs20545245 [D] KOG0588 Serine/threonine protein kinase 84 6e-16
At2g25880 [D] KOG0580 Serine/threonine protein kinase 84 6e-16
At5g39440 [T] KOG0583 Serine/threonine protein kinase 84 7e-16
At2g37840 [OUT] KOG0595 Serine/threonine-protein kinase involved... 84 7e-16
At1g12680 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 84 7e-16
ECU07g0520 [T] KOG0616 cAMP-dependent protein kinase catalytic s... 83 1e-15
At4g14580 [T] KOG0583 Serine/threonine protein kinase 83 1e-15
Hs7706286 [T] KOG0033 Ca2+/calmodulin-dependent protein kinase E... 83 1e-15
Hs20127418 [T] KOG0033 Ca2+/calmodulin-dependent protein kinase ... 83 1e-15
CE26649 [D] KOG0575 Polo-like serine/threonine protein kinase 83 1e-15
At5g01820 [T] KOG0583 Serine/threonine protein kinase 83 1e-15
At1g48260 [T] KOG0583 Serine/threonine protein kinase 83 1e-15
7299160 [OUT] KOG0595 Serine/threonine-protein kinase involved i... 83 1e-15
Hs14728804 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase ... 82 2e-15
CE28251 [D] KOG0615 Serine/threonine protein kinase Chk2 and rel... 82 2e-15
At3g29160 [T] KOG0583 Serine/threonine protein kinase 82 2e-15
Hs7662210 [OUT] KOG0595 Serine/threonine-protein kinase involved... 82 2e-15
Hs13899225 [R] KOG0586 Serine/threonine protein kinase 82 2e-15
At3g06030 [T] KOG0198 MEKK and related serine/threonine protein ... 82 2e-15
7304358 [T] KOG0033 Ca2+/calmodulin-dependent protein kinase EF-... 82 2e-15
7302464 [R] KOG0586 Serine/threonine protein kinase 82 2e-15
YDR507c [D] KOG0588 Serine/threonine protein kinase 82 3e-15
Hs20479818 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase ... 82 3e-15
Hs14141724 [T] KOG0033 Ca2+/calmodulin-dependent protein kinase ... 82 3e-15
At4g32830 [D] KOG0580 Serine/threonine protein kinase 82 3e-15
SPCC320.12c [D] KOG0580 Serine/threonine protein kinase 81 4e-15
Hs7661974 [T] KOG0583 Serine/threonine protein kinase 81 4e-15
CE21025 [D] KOG0580 Serine/threonine protein kinase 81 4e-15
At5g58380 [T] KOG0583 Serine/threonine protein kinase 81 4e-15
At5g07070 [T] KOG0583 Serine/threonine protein kinase 81 4e-15
7299507 [T] KOG0607 MAP kinase-interacting kinase and related se... 81 4e-15
7290150 [T] KOG0583 Serine/threonine protein kinase 81 4e-15
Hs21359873 [D] KOG0575 Polo-like serine/threonine protein kinase 81 5e-15
YBR274w [D] KOG0590 Checkpoint kinase and related serine/threoni... 80 6e-15
HsM4505191 [T] KOG0607 MAP kinase-interacting kinase and related... 80 6e-15
Hs9994197 [T] KOG0607 MAP kinase-interacting kinase and related ... 80 6e-15
Hs4502553 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 80 6e-15
CE27768 [R] KOG0586 Serine/threonine protein kinase 80 6e-15
CE23838 [R] KOG0586 Serine/threonine protein kinase 80 6e-15
SPCC74.03c [T] KOG0583 Serine/threonine protein kinase 80 8e-15
Hs8923922 [R] KOG0586 Serine/threonine protein kinase 80 8e-15
Hs14196445 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase ... 80 8e-15
CE27297 [D] KOG0615 Serine/threonine protein kinase Chk2 and rel... 80 8e-15
YGL158w [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-... 80 1e-14
CE28218 [D] KOG0588 Serine/threonine protein kinase 80 1e-14
At3g61960 [OUT] KOG0595 Serine/threonine-protein kinase involved... 80 1e-14
7293496 [R] KOG0597 Serine-threonine protein kinase FUSED 80 1e-14
Hs9845489 [R] KOG0586 Serine/threonine protein kinase 79 1e-14
Hs9845487 [R] KOG0586 Serine/threonine protein kinase 79 1e-14
Hs22062450 [R] KOG0586 Serine/threonine protein kinase 79 1e-14
CE09360 [Z] KOG0613 Projectin/twitchin and related proteins 79 1e-14
At2g38490 [T] KOG0583 Serine/threonine protein kinase 79 1e-14
Hs4507831 [OUT] KOG0595 Serine/threonine-protein kinase involved... 79 2e-14
CE25046 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-... 79 2e-14
CE24516 [OUT] KOG0595 Serine/threonine-protein kinase involved i... 79 2e-14
CE20636 [D] KOG0590 Checkpoint kinase and related serine/threoni... 79 2e-14
CE05780 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-... 79 2e-14
At5g57630 [T] KOG0583 Serine/threonine protein kinase 79 2e-14
7294217 [D] KOG0588 Serine/threonine protein kinase 79 2e-14
Hs4759178 [D] KOG0580 Serine/threonine protein kinase 79 2e-14
SPCC1322.08 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase... 78 3e-14
HsM4826916 [D] KOG0575 Polo-like serine/threonine protein kinase 78 3e-14
At1g54960 [T] KOG0198 MEKK and related serine/threonine protein ... 78 4e-14
Hs4758128_2 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase... 78 4e-14
HsM4505103 [R] KOG0586 Serine/threonine protein kinase 77 5e-14
CE00847 [T] KOG0583 Serine/threonine protein kinase 77 5e-14
At5g63650 [T] KOG0583 Serine/threonine protein kinase 77 5e-14
Hs14759411 [TR] KOG0606 Microtubule-associated serine/threonine ... 77 7e-14
7299437 [R] KOG0586 Serine/threonine protein kinase 77 7e-14
YKL101w [D] KOG0588 Serine/threonine protein kinase 77 9e-14
CE20167 [T] KOG4236 Serine/threonine protein kinase PKC mu/PKD a... 77 9e-14
CE17305 [T] KOG0665 Jun-N-terminal kinase (JNK) 77 9e-14
CE07156 [RT] KOG0598 Ribosomal protein S6 kinase and related pro... 77 9e-14
At1g09000 [T] KOG0198 MEKK and related serine/threonine protein ... 76 1e-13
7304311 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-... 76 1e-13
7292679 [G] KOG0599 Phosphorylase kinase gamma subunit 76 1e-13
7299322 [R] KOG0611 Predicted serine/threonine protein kinase 76 2e-13
Hs5174701 [T] KOG0579 Ste20-like serine/threonine protein kinase 75 2e-13
CE28643 [T] KOG0583 Serine/threonine protein kinase 75 2e-13
CE07458 [T] KOG0583 Serine/threonine protein kinase 75 2e-13
At3g13530 [T] KOG0198 MEKK and related serine/threonine protein ... 75 2e-13
7291043 [T] KOG0660 Mitogen-activated protein kinase 75 2e-13
Hs14993776 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase ... 75 3e-13
Hs13569922 [R] KOG0611 Predicted serine/threonine protein kinase 75 3e-13
CE28061 [T] KOG0033 Ca2+/calmodulin-dependent protein kinase EF-... 75 3e-13
CE28060 [T] KOG0033 Ca2+/calmodulin-dependent protein kinase EF-... 75 3e-13
CE28059 [T] KOG0033 Ca2+/calmodulin-dependent protein kinase EF-... 75 3e-13
CE28058 [T] KOG0033 Ca2+/calmodulin-dependent protein kinase EF-... 75 3e-13
CE28057 [T] KOG0033 Ca2+/calmodulin-dependent protein kinase EF-... 75 3e-13
CE28056 [T] KOG0033 Ca2+/calmodulin-dependent protein kinase EF-... 75 3e-13
CE28055 [T] KOG0033 Ca2+/calmodulin-dependent protein kinase EF-... 75 3e-13
CE28054 [T] KOG0033 Ca2+/calmodulin-dependent protein kinase EF-... 75 3e-13
CE28053 [T] KOG0033 Ca2+/calmodulin-dependent protein kinase EF-... 75 3e-13
CE28051 [T] KOG0033 Ca2+/calmodulin-dependent protein kinase EF-... 75 3e-13
At3g52890 [R] KOG0610 Putative serine/threonine protein kinase 75 3e-13
Hs8923539 [R] KOG0597 Serine-threonine protein kinase FUSED 75 3e-13
ECU07g0360 [D] KOG0580 Serine/threonine protein kinase 75 3e-13
At4g33950 [T] KOG0583 Serine/threonine protein kinase 75 3e-13
At3g07980 [T] KOG0198 MEKK and related serine/threonine protein ... 75 3e-13
SPCC162.10 [RT] KOG0598 Ribosomal protein S6 kinase and related ... 74 5e-13
At4g40010 [T] KOG0583 Serine/threonine protein kinase 74 5e-13
At2g23030 [T] KOG0583 Serine/threonine protein kinase 74 5e-13
7290147 [T] KOG0583 Serine/threonine protein kinase 74 5e-13
SPAC23C11.16 [D] KOG0575 Polo-like serine/threonine protein kinase 74 6e-13
Hs4506075 [T] KOG4236 Serine/threonine protein kinase PKC mu/PKD... 74 6e-13
At5g08590 [T] KOG0583 Serine/threonine protein kinase 74 6e-13
At3g49370 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 74 6e-13
At1g61950 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 74 6e-13
7302570 [R] KOG0586 Serine/threonine protein kinase 74 6e-13
Hs6005922_2 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase... 74 6e-13
YCL024w [T] KOG0583 Serine/threonine protein kinase 74 8e-13
SPAC9G1.02 [T] KOG4645 MAPKKK (MAP kinase kinase kinase) SSK2 an... 74 8e-13
At5g66880 [T] KOG0583 Serine/threonine protein kinase 74 8e-13
YOR233w [T] KOG0583 Serine/threonine protein kinase 73 1e-12
Hs21361643 [T] KOG4717 Serine/threonine protein kinase 73 1e-12
ECU01g0630 [D] KOG0575 Polo-like serine/threonine protein kinase 73 1e-12
At5g23580 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 73 1e-12
7303211 [T] KOG4717 Serine/threonine protein kinase 73 1e-12
7300773 [DKL] KOG0659 Cdk activating kinase (CAK)/RNA polymerase... 73 1e-12
7298323 [D] KOG0590 Checkpoint kinase and related serine/threoni... 73 1e-12
7290249 [R] KOG0586 Serine/threonine protein kinase 73 1e-12
Hs5453966 [T] KOG0583 Serine/threonine protein kinase 72 2e-12
Hs22043888 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase ... 72 2e-12
CE02377 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-... 72 2e-12
SPAC57A10.02 [D] KOG0588 Serine/threonine protein kinase 72 2e-12
Hs4502557 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 72 2e-12
Hs16950621 [Z] KOG0613 Projectin/twitchin and related proteins 72 2e-12
Hs16950613 [Z] KOG0613 Projectin/twitchin and related proteins 72 2e-12
Hs16950611 [Z] KOG0613 Projectin/twitchin and related proteins 72 2e-12
Hs16950601 [Z] KOG0613 Projectin/twitchin and related proteins 72 2e-12
CE21879 [D] KOG0590 Checkpoint kinase and related serine/threoni... 72 2e-12
At1g76040 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 72 2e-12
YCR073c [T] KOG4645 MAPKKK (MAP kinase kinase kinase) SSK2 and r... 72 3e-12
Hs14670383 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase ... 72 3e-12
At1g35670 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 72 3e-12
At1g12580 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 72 3e-12
SPAC890.03 [T] KOG0583 Serine/threonine protein kinase 71 4e-12
YGL179c [T] KOG0585 Ca2+/calmodulin-dependent protein kinase kin... 71 5e-12
Hs4557511 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 71 5e-12
Hs19923407 [D] KOG0591 NIMA (never in mitosis)-related G2-specif... 71 5e-12
At4g09570 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 71 5e-12
CE18058_1 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 71 5e-12
Hs5453964 [T] KOG0583 Serine/threonine protein kinase 70 7e-12
Hs4502803 [D] KOG0590 Checkpoint kinase and related serine/threo... 70 9e-12
Hs14777335 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase ... 70 9e-12
At5g40440 [T] KOG0581 Mitogen-activated protein kinase kinase (M... 70 9e-12
At1g69220 [T] KOG0576 Mitogen-activated protein kinase kinase ki... 70 9e-12
7300149 [T] KOG0578 p21-activated serine/threonine protein kinase 70 9e-12
YNL298w [T] KOG0578 p21-activated serine/threonine protein kinase 70 1e-11
SPBC1604.14c [T] KOG0578 p21-activated serine/threonine protein ... 70 1e-11
SPAC644.06c [D] KOG0588 Serine/threonine protein kinase 70 1e-11
HsM8923212 [T] KOG4717 Serine/threonine protein kinase 70 1e-11
Hs7662170 [R] KOG0611 Predicted serine/threonine protein kinase 70 1e-11
Hs4507281 [R] KOG0593 Predicted protein kinase KKIAMRE 70 1e-11
Hs22045207 [T] KOG0986 G protein-coupled receptor kinase 70 1e-11
Hs19424132 [D] KOG0591 NIMA (never in mitosis)-related G2-specif... 70 1e-11
Hs14770402 [R] KOG0586 Serine/threonine protein kinase 70 1e-11
At4g21940 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 70 1e-11
At1g50700 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 70 1e-11
Hs22057171 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase ... 69 1e-11
At4g23650 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 69 1e-11
YDR477w [T] KOG0583 Serine/threonine protein kinase 69 2e-11
At5g19360 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 69 2e-11
At5g12180 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 69 2e-11
7297080 [T] KOG0583 Serine/threonine protein kinase 69 2e-11
YNR031c [T] KOG4645 MAPKKK (MAP kinase kinase kinase) SSK2 and r... 69 2e-11
SPBC4F6.06 [T] KOG0583 Serine/threonine protein kinase 69 2e-11
Hs4505785 [G] KOG0599 Phosphorylase kinase gamma subunit 69 2e-11
At4g04720 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 69 2e-11
YPL141c [T] KOG0583 Serine/threonine protein kinase 68 3e-11
YLR362w [T] KOG0198 MEKK and related serine/threonine protein ki... 68 3e-11
YLR096w [T] KOG0583 Serine/threonine protein kinase 68 3e-11
SPBC1D7.05c [T] KOG0198 MEKK and related serine/threonine protei... 68 3e-11
At4g04740 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 68 3e-11
Hs5453882 [G] KOG0599 Phosphorylase kinase gamma subunit 68 4e-11
CE28674 [T] KOG0201 Serine/threonine protein kinase 68 4e-11
CE07510 [T] KOG0201 Serine/threonine protein kinase 68 4e-11
7304283 [Z] KOG0613 Projectin/twitchin and related proteins 68 4e-11
7299438 [R] KOG0586 Serine/threonine protein kinase 68 4e-11
7293512 [RT] KOG0598 Ribosomal protein S6 kinase and related pro... 68 4e-11
Hs22043324 [T] KOG0603 Ribosomal protein S6 kinase 67 6e-11
CE21615 [T] KOG0578 p21-activated serine/threonine protein kinase 67 6e-11
At3g04530 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 67 6e-11
At1g53570 [T] KOG0198 MEKK and related serine/threonine protein ... 67 6e-11
7296128 [T] KOG0583 Serine/threonine protein kinase 67 7e-11
At3g50500 [T] KOG0583 Serine/threonine protein kinase 67 9e-11
ECU08g1790 [D] KOG0600 Cdc2-related protein kinase 66 1e-10
CE26076 [D] KOG0590 Checkpoint kinase and related serine/threoni... 66 2e-10
7300413 [T] KOG0583 Serine/threonine protein kinase 66 2e-10
SPCC297.03 [T] KOG0585 Ca2+/calmodulin-dependent protein kinase ... 65 2e-10
At3g20410 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 65 2e-10
CE21086 [D] KOG0590 Checkpoint kinase and related serine/threoni... 65 3e-10
CE12518 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-... 65 3e-10
SPBC18H10.15 [R] KOG0663 Protein kinase PITSLRE and related kinases 65 4e-10
CE01146 [T] KOG0585 Ca2+/calmodulin-dependent protein kinase kin... 65 4e-10
At2g46700 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 65 4e-10
YPL140c [T] KOG0581 Mitogen-activated protein kinase kinase (MAP2K) 64 5e-10
YOR351c [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-... 64 5e-10
YHR102w [T] KOG0201 Serine/threonine protein kinase 64 5e-10
At4g08500 [T] KOG0198 MEKK and related serine/threonine protein ... 64 5e-10
SPAC1F5.09c [T] KOG0578 p21-activated serine/threonine protein k... 64 6e-10
Hs7661994 [T] KOG0579 Ste20-like serine/threonine protein kinase 64 6e-10
CE29466 [T] KOG0665 Jun-N-terminal kinase (JNK) 64 6e-10
7302908 [R] KOG0594 Protein kinase PCTAIRE and related kinases 64 6e-10
SPAC29A4.16 [D] KOG0590 Checkpoint kinase and related serine/thr... 64 8e-10
Hs17933758 [T] KOG0585 Ca2+/calmodulin-dependent protein kinase ... 64 8e-10
CE28479 [T] KOG0583 Serine/threonine protein kinase 64 8e-10
Hs20143922 [Z] KOG0613 Projectin/twitchin and related proteins 63 1e-09
Hs20143918 [Z] KOG0613 Projectin/twitchin and related proteins 63 1e-09
Hs20143914 [Z] KOG0613 Projectin/twitchin and related proteins 63 1e-09
Hs19747267 [Z] KOG0613 Projectin/twitchin and related proteins 63 1e-09
HsM5729922 [T] KOG0198 MEKK and related serine/threonine protein... 63 1e-09
At3g56760 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 63 1e-09
At1g49580 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 63 1e-09
At4g08470 [T] KOG0198 MEKK and related serine/threonine protein ... 62 2e-09
At2g41140 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 62 2e-09
7300650 [R] KOG0594 Protein kinase PCTAIRE and related kinases 62 2e-09
YCR008w [D] KOG0590 Checkpoint kinase and related serine/threoni... 62 2e-09
SPBC17F3.02 [T] KOG0201 Serine/threonine protein kinase 62 2e-09
YDL025c [D] KOG0590 Checkpoint kinase and related serine/threoni... 62 3e-09
SPAC23C11.11 [TDK] KOG0668 Casein kinase II alpha subunit 62 3e-09
Hs4502743 [DKL] KOG0659 Cdk activating kinase (CAK)/RNA polymera... 62 3e-09
Hs21450709 [RT] KOG0598 Ribosomal protein S6 kinase and related ... 62 3e-09
Hs20128768 [OUT] KOG0595 Serine/threonine-protein kinase involve... 62 3e-09
At3g19100 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 62 3e-09
At1g63700 [T] KOG0198 MEKK and related serine/threonine protein ... 62 3e-09
7289745 [TDK] KOG0668 Casein kinase II alpha subunit 62 3e-09
SPAC31G5.09c [T] KOG0660 Mitogen-activated protein kinase 61 4e-09
ECU03g0980 [T] KOG0583 Serine/threonine protein kinase 61 4e-09
YER129w [T] KOG0585 Ca2+/calmodulin-dependent protein kinase kin... 61 5e-09
Hs16507245 [T] KOG0583 Serine/threonine protein kinase 61 5e-09
At5g66210 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 61 5e-09
At4g38230 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 61 5e-09
Hs7706445 [T] KOG0664 Nemo-like MAPK-related serine/threonine pr... 60 7e-09
CE18366 [T] KOG0583 Serine/threonine protein kinase 60 7e-09
At5g50180 [T] KOG0192 Tyrosine kinase specific for activated (GT... 60 7e-09
At3g15220 [T] KOG0201 Serine/threonine protein kinase 60 7e-09
7297578 [T] KOG0661 MAPK related serine/threonine protein kinase 60 7e-09
YLR113w [T] KOG0660 Mitogen-activated protein kinase 60 9e-09
SPCC63.08c [OUT] KOG0595 Serine/threonine-protein kinase involve... 60 9e-09
At2g17290 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 60 9e-09
YBL016w [T] KOG0660 Mitogen-activated protein kinase 60 1e-08
HsM20070143 [T] KOG0665 Jun-N-terminal kinase (JNK) 60 1e-08
Hs4557439 [R] KOG0594 Protein kinase PCTAIRE and related kinases 60 1e-08
Hs22065405 [RT] KOG0598 Ribosomal protein S6 kinase and related ... 60 1e-08
Hs21237739 [T] KOG0665 Jun-N-terminal kinase (JNK) 60 1e-08
Hs21237736 [T] KOG0665 Jun-N-terminal kinase (JNK) 60 1e-08
Hs14150045 [T] KOG0585 Ca2+/calmodulin-dependent protein kinase ... 59 2e-08
7291778 [T] KOG0579 Ste20-like serine/threonine protein kinase 59 2e-08
SPAC1D4.11c [T] KOG0671 LAMMER dual specificity kinases 59 2e-08
At2g23070 [TDK] KOG0668 Casein kinase II alpha subunit 59 2e-08
At2g17890 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 59 2e-08
YIL035c [TDK] KOG0668 Casein kinase II alpha subunit 58 3e-08
SPBC16E9.13 [T] KOG0583 Serine/threonine protein kinase 58 3e-08
Hs7706059 [R] KOG0593 Predicted protein kinase KKIAMRE 58 3e-08
Hs18596354 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase ... 58 3e-08
SPBC32H8.10 [D] KOG0600 Cdc2-related protein kinase 58 4e-08
SPAC2F3.15 [D] KOG0600 Cdc2-related protein kinase 58 4e-08
At1g73500 [T] KOG0581 Mitogen-activated protein kinase kinase (M... 58 4e-08
SPBPI064 [G] KOG0658 Glycogen synthase kinase-3 57 6e-08
SPBC8D2.01 [G] KOG0658 Glycogen synthase kinase-3 57 6e-08
ECU02g1450 [DKL] KOG0659 Cdk activating kinase (CAK)/RNA polymer... 57 6e-08
>YGR092w [R] KOG0605 NDR and related serine/threonine kinases
Length = 572
Score = 759 bits (1960), Expect = 0.0
Identities = 381/570 (66%), Positives = 451/570 (78%), Gaps = 17/570 (2%)
Query: 11 KEVDALVDDMVNFSFD---TDAKVMLDPPST-------PTRIRGSPSPTR-SIVKNPENS 59
K VD L +M N SFD T L P P I SPSP + S + S
Sbjct: 7 KNVDLLAGNMSNLSFDGHGTPGGTGLFPNQNITKRRTRPAGINDSPSPVKPSFFPYEDTS 66
Query: 60 LMDIDDDTQGDLTADITKSPKKLPKDFYKKSSKTKSKRLVSVCQMYFLDYYCDMFDYVIS 119
MDID+ +Q D+ D++ SPKKLP FY++++ K++R+VSVC+MYFL++YCDMFDYVIS
Sbjct: 67 NMDIDEVSQPDM--DVSNSPKKLPPKFYERATSNKTQRVVSVCKMYFLEHYCDMFDYVIS 124
Query: 120 RRERTRQVINYLEEQRRSNLMGTEQI--TNEWQGYLTKETNILRKRRLKPKHKDFEMITX 177
RR+RT+QV+ YL++Q S L ++QI EW YL +E +LRKRRLKPK++DFEMIT
Sbjct: 125 RRQRTKQVLEYLQQQ--SQLPNSDQIKLNEEWSSYLQREHQVLRKRRLKPKNRDFEMITQ 182
Query: 178 XXXXXXXXXXLARKKDTKEICAXXXXXXXXXXXXEGTDHVLTERDILTTTRSEWLVKLLY 237
LARKKDTKE+CA T HVLTERDILTTTRSEWLVKLLY
Sbjct: 183 VGQGGYGQVYLARKKDTKEVCALKILNKKLLFKLNETKHVLTERDILTTTRSEWLVKLLY 242
Query: 238 AFQDPQSLYLAMEFVPGGDFRTLLLNTKFLQAPHARFYISEMFCAVNALHQLGYTHRDLK 297
AFQD QSLYLAMEFVPGGDFRTLL+NT+ L++ HARFYISEMFCAVNALH LGYTHRDLK
Sbjct: 243 AFQDLQSLYLAMEFVPGGDFRTLLINTRCLKSGHARFYISEMFCAVNALHDLGYTHRDLK 302
Query: 298 PENFLIDSKGHIKLTDFGLASGTVSMERIESMKIRLQEVKNLEFPEFRERSMDDRRRMYN 357
PENFLID+KGHIKLTDFGLA+GT+S ERIESMKIRL+++K+LEFP F E+S++DRR+MYN
Sbjct: 303 PENFLIDAKGHIKLTDFGLAAGTISNERIESMKIRLEKIKDLEFPAFTEKSIEDRRKMYN 362
Query: 358 KLREEEVRYAHSTVGSPDYMALEVLEAKNYDFTVDYWSLGCILFESLVGYTPFSGNSTNE 417
+LRE+E+ YA+S VGSPDYMALEVLE K YDFTVDYWSLGC+LFESLVGYTPFSG+STNE
Sbjct: 363 QLREKEINYANSMVGSPDYMALEVLEGKKYDFTVDYWSLGCMLFESLVGYTPFSGSSTNE 422
Query: 418 TYENLRNWKHVLQRPKCDNGRYAFSDRTWELITRLIADPINRLKSFEHVKRMRYFSEIDF 477
TY+NLR WK L+RP+ +GR AFSDRTW+LITRLIADPINRL+SFEHVKRM YF++I+F
Sbjct: 423 TYDNLRRWKQTLRRPRQSDGRAAFSDRTWDLITRLIADPINRLRSFEHVKRMSYFADINF 482
Query: 478 NTLRTIHPPFIPQLDNEEDVGYFDDFTNEEHMARYVDVFKRQDRLTAMVDDSLSDSKLVG 537
+TLR++ PPF PQLD+E D GYFDDFT+E MA+Y DVFKRQD+LTAMVDDS SKLVG
Sbjct: 483 STLRSMIPPFTPQLDSETDAGYFDDFTSEADMAKYADVFKRQDKLTAMVDDSAVSSKLVG 542
Query: 538 FTFRHRNGKDGSSGVLYGGLEQSDPFATFY 567
FTFRHRNGK GSSG+L+ GLE SDPF+TFY
Sbjct: 543 FTFRHRNGKQGSSGILFNGLEHSDPFSTFY 572
>YPR111w [R] KOG0605 NDR and related serine/threonine kinases
Length = 564
Score = 739 bits (1908), Expect = 0.0
Identities = 368/574 (64%), Positives = 441/574 (76%), Gaps = 17/574 (2%)
Query: 1 MFTRDANGRHKEVDALVDDMVNFSF-------DTDAKVMLDPPSTPTRIRGSPSPTRSIV 53
MF+R +EVD L +M + F T + P R +P RS
Sbjct: 1 MFSRS----DREVDDLAGNMSHLGFYDLNIPKPTSPQAQYRPARKSENGRLTPGLPRSYK 56
Query: 54 KNPENSLMDIDDDTQGDLTADITKSPKKLPKDFYKKSSKTKSKRLVSVCQMYFLDYYCDM 113
D DD + SPKKLPKDF++++S++K++R+V+VCQ+YFLDYYCDM
Sbjct: 57 P------CDSDDQDTFKNRISLNHSPKKLPKDFHERASQSKTQRVVNVCQLYFLDYYCDM 110
Query: 114 FDYVISRRERTRQVINYLEEQRRSNLMGTEQITNEWQGYLTKETNILRKRRLKPKHKDFE 173
FDYVISRR+RT+QV+ YLE+QR + + + EW YL +E +LRKRRLKPKHKDF+
Sbjct: 111 FDYVISRRQRTKQVLRYLEQQRSVKNVSNKVLNEEWALYLQREHEVLRKRRLKPKHKDFQ 170
Query: 174 MITXXXXXXXXXXXLARKKDTKEICAXXXXXXXXXXXXEGTDHVLTERDILTTTRSEWLV 233
++T LA+KKD+ EICA T+HVLTERDILTTTRS+WLV
Sbjct: 171 ILTQVGQGGYGQVYLAKKKDSDEICALKILNKKLLFKLNETNHVLTERDILTTTRSDWLV 230
Query: 234 KLLYAFQDPQSLYLAMEFVPGGDFRTLLLNTKFLQAPHARFYISEMFCAVNALHQLGYTH 293
KLLYAFQDP+SLYLAMEFVPGGDFRTLL+NT+ L++ HARFYISEMFCAVNALH+LGYTH
Sbjct: 231 KLLYAFQDPESLYLAMEFVPGGDFRTLLINTRILKSGHARFYISEMFCAVNALHELGYTH 290
Query: 294 RDLKPENFLIDSKGHIKLTDFGLASGTVSMERIESMKIRLQEVKNLEFPEFRERSMDDRR 353
RDLKPENFLID+ GHIKLTDFGLA+GTVS ERIESMKIRL+EVKNLEFP F ERS++DRR
Sbjct: 291 RDLKPENFLIDATGHIKLTDFGLAAGTVSNERIESMKIRLEEVKNLEFPAFTERSIEDRR 350
Query: 354 RMYNKLREEEVRYAHSTVGSPDYMALEVLEAKNYDFTVDYWSLGCILFESLVGYTPFSGN 413
++Y+ +R+ E+ YA+S VGSPDYMALEVLE K YDFTVDYWSLGC+LFESLVGYTPFSG+
Sbjct: 351 KIYHNMRKTEINYANSMVGSPDYMALEVLEGKKYDFTVDYWSLGCMLFESLVGYTPFSGS 410
Query: 414 STNETYENLRNWKHVLQRPKCDNGRYAFSDRTWELITRLIADPINRLKSFEHVKRMRYFS 473
STNETYENLR WK L+RP+ ++ R AFSDRTW+LITRLIADPINR++SFE V++M YF+
Sbjct: 411 STNETYENLRYWKKTLRRPRTEDRRAAFSDRTWDLITRLIADPINRVRSFEQVRKMSYFA 470
Query: 474 EIDFNTLRTIHPPFIPQLDNEEDVGYFDDFTNEEHMARYVDVFKRQDRLTAMVDDSLSDS 533
EI+F TLRT PPFIPQLD+E D GYFDDFTNEE MA+Y DVFKRQ++L+AMVDDS DS
Sbjct: 471 EINFETLRTSSPPFIPQLDDETDAGYFDDFTNEEDMAKYADVFKRQNKLSAMVDDSAVDS 530
Query: 534 KLVGFTFRHRNGKDGSSGVLYGGLEQSDPFATFY 567
KLVGFTFRHR+GK GSSG+LY G E SDPF+TFY
Sbjct: 531 KLVGFTFRHRDGKQGSSGILYNGSEHSDPFSTFY 564
>SPAC24B11.11c [R] KOG0605 NDR and related serine/threonine kinases
Length = 607
Score = 440 bits (1132), Expect = e-123
Identities = 227/469 (48%), Positives = 310/469 (65%), Gaps = 15/469 (3%)
Query: 88 KKSSKTKSKRLVSVCQMYFLDYYCDMFDYVISRRERTRQVINYLEEQRRSNLMGTEQITN 147
+K + K KR+ ++CQM+FLD+Y + Y+ +R++R R L ++ S +++
Sbjct: 130 EKVVQPKVKRMATICQMFFLDHYFEQLHYLYTRKQRARLFEEQLLKEPDSR---RDELVK 186
Query: 148 EWQGYLTKETNILRKRRLKPKHKDFEMITXXXXXXXXXXXLARKKDTKEICAXXXXXXXX 207
+ G +E LRKRR + H DF+ IT LARK+DTKEI A
Sbjct: 187 RYNG---RERVYLRKRRTRISHGDFQTITQVGQGGYGSVWLARKRDTKEIVALKIMNKSV 243
Query: 208 XXXXEGTDHVLTERDILTTTRSEWLVKLLYAFQDPQSLYLAMEFVPGGDFRTLLLNTKFL 267
+ HVLTERDILTT SEWLV+LLYAFQD ++YLAMEFVPGGDFRTLL N+ L
Sbjct: 244 LHKMDEIRHVLTERDILTTANSEWLVRLLYAFQDTSNIYLAMEFVPGGDFRTLLSNSGVL 303
Query: 268 QAPHARFYISEMFCAVNALHQLGYTHRDLKPENFLIDSKGHIKLTDFGLASGTVSMERIE 327
+ HA+FY +EMF A++ALHQLGY HRDLKPENFL+ + GHIKLTDFGL+SG +S ++IE
Sbjct: 304 RDHHAKFYATEMFLAIDALHQLGYIHRDLKPENFLVGASGHIKLTDFGLSSGIISKKKIE 363
Query: 328 SMKIRLQEVKNLEFPEFRERSMDDRRRMYNKLREEEVRYAHSTVGSPDYMALEVLEAKNY 387
SMKIRLQEV N+ P ERSM +RR+++ L ++ YAHS VGSPDYMA EVL +NY
Sbjct: 364 SMKIRLQEVNNVVVP---ERSMRERRQVFRTLLSQDPVYAHSVVGSPDYMAPEVLRGENY 420
Query: 388 DFTVDYWSLGCILFESLVGYTPFSGNSTNETYENLRNWKHVLQRPKCDNGR---YAFSDR 444
+ +VDYWSLGCI++E L G+ PFSG++ NET+ NL+NW+ QRP D+ R + + D
Sbjct: 421 NHSVDYWSLGCIMYECLSGFPPFSGSNVNETWSNLKNWRKCFQRPHYDDPRDLEFNWRDD 480
Query: 445 TWELITRLIADPINRLKSFEHVKRMRYFSEIDFNTLRTIH-PPFIPQLDNEEDVGYFDDF 503
W+ + I DP +R S + V + YFS+ID+ +RT + PPF+P L++E D GYFDDF
Sbjct: 481 AWDFVCHCITDPKDRFCSLKQVMQHPYFSKIDWKNVRTAYRPPFVPDLNSEIDAGYFDDF 540
Query: 504 TNEEHMARYVDVFKRQDRLTAMVD--DSLSDSKLVGFTFRHRNGKDGSS 550
TNE M++Y +V ++Q + MV+ + + +GFTFRH+ +S
Sbjct: 541 TNENDMSKYKEVHEKQAAIANMVNTFNKPKRNAFIGFTFRHQKNSHPTS 589
>SPCC417.06c [R] KOG0605 NDR and related serine/threonine kinases
Length = 624
Score = 348 bits (893), Expect = 1e-95
Identities = 185/467 (39%), Positives = 274/467 (58%), Gaps = 26/467 (5%)
Query: 91 SKTKSKRLVSVCQMYFLDYYCDMFDYVISRRERTRQVI---NYLEEQRRSNLMGTEQITN 147
S+ +++R CQ++FL+YY +Y R+ER + + L++ ++ L
Sbjct: 87 SRPETRRKRMACQVFFLNYYISTIEYHKLRKERLEEFTACTSSLKQSKQKRL-------- 138
Query: 148 EWQGYLTKETNILRKRRLKPKHKDFEMITXXXXXXXXXXXLARKKDTKEICAXXXXXXXX 207
W+ + +E LRK+R K + F+++ LA+K++T E+ A
Sbjct: 139 -WKEHCGRERAFLRKKRTKIQCSHFDLLVKLGQGGYGSVWLAKKRNTHELLAMKMMKKST 197
Query: 208 XXXXEGTDHVLTERDILTTTRSEWLVKLLYAFQDPQSLYLAMEFVPGGDFRTLLLNTKFL 267
H+L ERDILT T SEWLVKL YAFQD + +YLAME+VPGGDFRT L L
Sbjct: 198 LQQLNEVKHILNERDILTNTNSEWLVKLYYAFQDKEKVYLAMEYVPGGDFRTFLTTKGLL 257
Query: 268 QAPHARFYISEMFCAVNALHQLGYTHRDLKPENFLIDSKGHIKLTDFGLASGTVSMERIE 327
RFY++EM A++A+H+LGY HRDLKPENFLID KGHIKL+DFGL++ V+ ++
Sbjct: 258 HENQTRFYLAEMVAAISAVHKLGYMHRDLKPENFLIDQKGHIKLSDFGLSTAIVTSNQVN 317
Query: 328 SMKIRLQEVKNLEFPEFRERSMDDRRRMYNKLREEEVRYAHSTVGSPDYMALEVLEAKNY 387
++ L N + P ++ RR +Y L E+ +S VGSP+YMA EV+ K Y
Sbjct: 318 RLQHALVSAVNPQRPYLTQK---QRRNIYKALLEKNENKVNSVVGSPEYMAPEVVYGKKY 374
Query: 388 DFTVDYWSLGCILFESLVGYTPFSGNSTNETYENLRNWKHVLQRP-KCDNGRY-----AF 441
D TVDYWSLGCI +E LVGY PFSG++ ET+ NL W+ +LQRP K +NG Y +
Sbjct: 375 DRTVDYWSLGCICYECLVGYPPFSGSTLQETWTNLYYWREMLQRPSKNENGIYDKKARSV 434
Query: 442 SDRTWELITRLIADPINRLKSFEHVKRMRYFSEIDFNTLR-TIHPPFIPQLDNEEDVGYF 500
SD W IT+ + +P +R +S +++ +F + +N LR PPF+P+L+N+ D YF
Sbjct: 435 SDEAWSFITKCLTEPTSRFQSTIEIQKHPFFKRLHWNGLRKRAVPPFVPRLENQLDTSYF 494
Query: 501 DDFTNEEHMARYVDVFKRQDRLTAMVDD----SLSDSKLVGFTFRHR 543
DDF +E+ + Y DV+++Q + + + + +GFTF++R
Sbjct: 495 DDFNDEQVLDAYKDVYEKQRKAEQKAKSNGVMNGNQRQFLGFTFKYR 541
>Hs18579683 [R] KOG0605 NDR and related serine/threonine kinases
Length = 464
Score = 232 bits (592), Expect = 1e-60
Identities = 138/416 (33%), Positives = 215/416 (51%), Gaps = 17/416 (4%)
Query: 95 SKRLVSVCQMYFLDYYCDMFDYVISRRERTRQVINYLEEQRRSNLMGTEQITNEWQGYLT 154
++ V+V ++ ++Y ++ R R +++ +EE+ + E+ +
Sbjct: 17 TRERVTVAKLTLENFYSNLILQHEERETRQKKLEVAMEEEG----LADEEKKLRRSQHAR 72
Query: 155 KETNILRKRRLKPKHKDFEMITXXXXXXXXXXXLARKKDTKEICAXXXXXXXXXXXXEGT 214
KET LR +R + DFE + L +KKDT I A E
Sbjct: 73 KETEFLRLKRTRLGLDDFESLKVIGRGAFGEVRLVQKKDTGHIYAMKILRKSDMLEKEQV 132
Query: 215 DHVLTERDILTTTRSEWLVKLLYAFQDPQSLYLAMEFVPGGDFRTLLLNTKFLQAPHARF 274
H+ ERDIL W+VK+ Y+FQD ++LYL MEF+PGGD TLL+ L +F
Sbjct: 133 AHIRAERDILVEADGAWVVKMFYSFQDKRNLYLIMEFLPGGDMMTLLMKKDTLTEEETQF 192
Query: 275 YISEMFCAVNALHQLGYTHRDLKPENFLIDSKGHIKLTDFGLASGTVSMERIESMKIRLQ 334
YISE A++A+HQLG+ HRD+KP+N L+D+KGH+KL+DFGL +G R E +
Sbjct: 193 YISETVLAIDAIHQLGFIHRDIKPDNLLLDAKGHVKLSDFGLCTGLKKAHRTEFYR---- 248
Query: 335 EVKNLEFPEFRERSMDDRRRMYNKLREEEVRYAHSTVGSPDYMALEVLEAKNYDFTVDYW 394
+ + +F ++M+ +R+ ++ + A+STVG+PDY+A EV Y+ D+W
Sbjct: 249 NLTHNPPSDFSFQNMNSKRKA-ETWKKNRRQLAYSTVGTPDYIAPEVFMQTGYNKLCDWW 307
Query: 395 SLGCILFESLVGYTPFSGNSTNETYENLRNWKHVLQRPKCDNGRYAFSDRTWELITRLIA 454
SLG I++E L+GY PF + ETY + NWK L P S++ +LI R
Sbjct: 308 SLGVIMYEMLIGYPPFCSETPQETYRKVMNWKETLVFPP----EVPISEKAKDLILRFCI 363
Query: 455 DPINRL--KSFEHVKRMRYFSEIDFNTLRTIHPPFIP-QLDNEEDVGYFDDFTNEE 507
D NR+ E +K +F +D+ +R P IP ++ + +D FDDF +
Sbjct: 364 DSENRIGNSGVEEIKGHPFFEGVDWEHIRE-RPAAIPIEIKSIDDTSNFDDFPESD 418
>SPAC821.12 [R] KOG0605 NDR and related serine/threonine kinases
Length = 469
Score = 228 bits (580), Expect = 2e-59
Identities = 148/429 (34%), Positives = 217/429 (50%), Gaps = 24/429 (5%)
Query: 77 KSPKKLPKDFYKKSSKTKSKRLVSVCQMYFLDYYCDMFDYVISRRERTRQVINYLEEQRR 136
++P PK K KTK Y YY D+ + R +R + EQR
Sbjct: 11 RNPSLFPKSTLDKVQKTKK---------YIEHYYKVAVDHAVERNQRRINL-----EQRL 56
Query: 137 SNLMGTEQITN-EWQGYLTKETNILRKRRLKPKHKDFEMITXXXXXXXXXXXLARKKDTK 195
+ G+E+ N + + KE+ LR RR + +DF I L +K DT
Sbjct: 57 ATERGSEERKNRQLRASGEKESQFLRFRRTRLSLEDFSTIKVIGKGAFGEVRLVQKLDTG 116
Query: 196 EICAXXXXXXXXXXXXEGTDHVLTERDILTTTRSEWLVKLLYAFQDPQSLYLAMEFVPGG 255
+I A + HV ERD+L + S W+V L YAFQD LYL MEF+PGG
Sbjct: 117 KIYAMKSLLKTEMFKRDQLAHVKAERDLLVESDSPWVVSLYYAFQDSLYLYLIMEFLPGG 176
Query: 256 DFRTLLLNTKFLQAPHARFYISEMFCAVNALHQLGYTHRDLKPENFLIDSKGHIKLTDFG 315
D T+L+N RFY++E A+ +H++GY HRD+KP+N LID GHIKL+DFG
Sbjct: 177 DLMTMLINYDTFSEDVTRFYMAECVLAIADVHRMGYIHRDIKPDNILIDRDGHIKLSDFG 236
Query: 316 LASGTVSMERIES-MKIRL-QEVKNLEFPEFRERSMDDRRRMYNKLREEEVRYAHSTVGS 373
L++G ++ S MK R VK + + +M + +M + V A+STVG+
Sbjct: 237 LSTGFYKQDQSASYMKPRTGNTVKRGQMVDAIWLTMSSKDKMATWKKNRRV-MAYSTVGT 295
Query: 374 PDYMALEVLEAKNYDFTVDYWSLGCILFESLVGYTPFSGNSTNETYENLRNWKHVLQRPK 433
PDY+A E+ + Y D+WSLG I+FE L+G+ PF +++ETY + NW+ L P
Sbjct: 296 PDYIAPEIFLQQGYGQDCDWWSLGAIMFECLIGWPPFCSENSHETYRKIINWRETLTFP- 354
Query: 434 CDNGRYAFSDRTWELITRLIADPINRLKSFEHVKRMR--YFSEIDFNTLRTIHPPFIPQL 491
S +L+ RL+ D +RL ++ M+ +F+ ID++ +R PFIP L
Sbjct: 355 ---NDIHLSIEARDLMDRLMTDSEHRLGRGGAIEIMQHPFFTGIDWDHIRETAAPFIPNL 411
Query: 492 DNEEDVGYF 500
+ D YF
Sbjct: 412 KSITDTHYF 420
>Hs6005814 [R] KOG0605 NDR and related serine/threonine kinases
Length = 465
Score = 227 bits (579), Expect = 3e-59
Identities = 133/420 (31%), Positives = 213/420 (50%), Gaps = 15/420 (3%)
Query: 90 SSKTKSKRLVSVCQMYFLDYYCDMFDYVISRRERTRQVINYLEEQRRSNLMGTEQITNEW 149
S +K V++ ++ ++Y ++ R R +++ +EE+ + E+
Sbjct: 11 SMSNHTKERVTMTKVTLENFYSNLIAQHEEREMRQKKLEKVMEEEGLKD----EEKRLRR 66
Query: 150 QGYLTKETNILRKRRLKPKHKDFEMITXXXXXXXXXXXLARKKDTKEICAXXXXXXXXXX 209
+ KET LR +R + +DFE + L +KKDT + A
Sbjct: 67 SAHARKETEFLRLKRTRLGLEDFESLKVIGRGAFGEVRLVQKKDTGHVYAMKILRKADML 126
Query: 210 XXEGTDHVLTERDILTTTRSEWLVKLLYAFQDPQSLYLAMEFVPGGDFRTLLLNTKFLQA 269
E H+ ERDIL S W+VK+ Y+FQD +LYL MEF+PGGD TLL+ L
Sbjct: 127 EKEQVGHIRAERDILVEADSLWVVKMFYSFQDKLNLYLIMEFLPGGDMMTLLMKKDTLTE 186
Query: 270 PHARFYISEMFCAVNALHQLGYTHRDLKPENFLIDSKGHIKLTDFGLASGTVSMERIESM 329
+FYI+E A++++HQLG+ HRD+KP+N L+DSKGH+KL+DFGL +G R E
Sbjct: 187 EETQFYIAETVLAIDSIHQLGFIHRDIKPDNLLLDSKGHVKLSDFGLCTGLKKAHRTEFY 246
Query: 330 KIRLQEVKNLEFPEFRERSMDDRRRMYNKLREEEVRYAHSTVGSPDYMALEVLEAKNYDF 389
+ + + +F ++M+ +R+ R + A STVG+PDY+A EV Y+
Sbjct: 247 RNLNHSLPS----DFTFQNMNSKRKAETWKRNRR-QLAFSTVGTPDYIAPEVFMQTGYNK 301
Query: 390 TVDYWSLGCILFESLVGYTPFSGNSTNETYENLRNWKHVLQRPKCDNGRYAFSDRTWELI 449
D+WSLG I++E L+GY PF + ETY+ + NWK L P S++ +LI
Sbjct: 302 LCDWWSLGVIMYEMLIGYPPFCSETPQETYKKVMNWKETLTFPP----EVPISEKAKDLI 357
Query: 450 TRLIADPINRL--KSFEHVKRMRYFSEIDFNTLRTIHPPFIPQLDNEEDVGYFDDFTNEE 507
R + +R+ E +K +F +D+ +R ++ + +D FD+F +
Sbjct: 358 LRFCCEWEHRIGAPGVEEIKSNSFFEGVDWEHIRERPAAISIEIKSIDDTSNFDEFPESD 417
>CE28760 [R] KOG0605 NDR and related serine/threonine kinases
Length = 467
Score = 226 bits (576), Expect = 7e-59
Identities = 138/421 (32%), Positives = 207/421 (48%), Gaps = 18/421 (4%)
Query: 90 SSKTKSKRLVSVCQMYFLDYYCDMFDYVISRRERTRQVINYLEEQRRSNLMGTEQITNEW 149
S TK K S ++ YY R R ++ LEE + + E+ +
Sbjct: 4 SQYTKDK--ASCTRISIESYYSKRVTQCAERENRLKK----LEEDISARGLSDEEKEEKR 57
Query: 150 QGYLTKETNILRKRRLKPKHKDFEMITXXXXXXXXXXXLARKKDTKEICAXXXXXXXXXX 209
+ + +KET+ LR +R + DFE + L +K DT I A
Sbjct: 58 KIHHSKETDYLRLKRTRLTVNDFESLKVIGRGAFGEVRLVQKHDTGHIYAMKILRKSEMV 117
Query: 210 XXEGTDHVLTERDILTTTRSEWLVKLLYAFQDPQSLYLAMEFVPGGDFRTLLLNTKFLQA 269
E T HV ERDIL+ +W+VK+ Y+FQD +LYL MEF+PGGD TLL+ L
Sbjct: 118 EKEQTAHVRAERDILSEADCDWVVKMYYSFQDYSNLYLVMEFLPGGDMMTLLIKKDTLTE 177
Query: 270 PHARFYISEMFCAVNALHQLGYTHRDLKPENFLIDSKGHIKLTDFGLASGTVSMERIESM 329
+FYI+E A+ +H LG+ HRD+KP+N L+D++GH+KL+DFGL +G R +
Sbjct: 178 EATQFYIAEAALAIQFIHSLGFIHRDIKPDNLLLDARGHVKLSDFGLCTGLKKFHRTDHY 237
Query: 330 KIRLQEVKNLEFPEFRERSMDDRRRMYNKLREEEVRYAHSTVGSPDYMALEVLEAKNYDF 389
+ + P+F + + +R+ R YA+STVG+PDY+A EV + Y
Sbjct: 238 RNWPSTLP----PDFISKPFESKRKAETWKRNRRA-YAYSTVGTPDYIAPEVFQPNGYTK 292
Query: 390 TVDYWSLGCILFESLVGYTPFSGNSTNETYENLRNWKHVLQRPKCDNGRYAFSDRTWELI 449
+ D+WSLG I++E L+GY PF ETY + NW+ L P S I
Sbjct: 293 SCDWWSLGVIMYEMLIGYPPFCSELPQETYRKVINWQQTLVFP----SDVPISIEAKATI 348
Query: 450 TRLIADPINRLKS---FEHVKRMRYFSEIDFNTLRTIHPPFIPQLDNEEDVGYFDDFTNE 506
R + RL + + +K+ + ID+N +R PP + + +D FDDF +E
Sbjct: 349 KRFCCEAERRLGNHGGLDEIKQCPFVKRIDWNHIRERPPPIRVTVKSIDDTSNFDDFPDE 408
Query: 507 E 507
+
Sbjct: 409 D 409
>7293735 [R] KOG0605 NDR and related serine/threonine kinases
Length = 459
Score = 226 bits (575), Expect = 9e-59
Identities = 135/400 (33%), Positives = 206/400 (50%), Gaps = 15/400 (3%)
Query: 108 DYYCDMFDYVISRRERTRQVINYLEEQRRSNLMGTEQITNEWQGYLTKETNILRKRRLKP 167
+YY ++ R++R + LE Q + + Q + + KET LR +RL+
Sbjct: 33 NYYSNLVTQYGERKQRLAK----LEAQLKDESLSEAQRQEKRLQHAQKETEYLRLKRLRL 88
Query: 168 KHKDFEMITXXXXXXXXXXXLARKKDTKEICAXXXXXXXXXXXXEGTDHVLTERDILTTT 227
+DFE + L +KKDT + A E HV ERD+L
Sbjct: 89 GVEDFEALKVIGRGAFGEVRLVQKKDTGHVYAMKVLRKADMLEKEQVAHVRAERDVLVEA 148
Query: 228 RSEWLVKLLYAFQDPQSLYLAMEFVPGGDFRTLLLNTKFLQAPHARFYISEMFCAVNALH 287
+W+VK+ Y+FQDP +LYL MEF+PGGD TLL+ L +FYISE A++++H
Sbjct: 149 DHQWVVKMYYSFQDPVNLYLIMEFLPGGDMMTLLMKKDTLSEEGTQFYISETALAIDSIH 208
Query: 288 QLGYTHRDLKPENFLIDSKGHIKLTDFGLASGTVSMERIESMKIRLQEVKNLEFPEFRER 347
+LG+ HRD+KP+N L+D++GH+KL+DFGL +G R + + L + K +F
Sbjct: 209 KLGFIHRDIKPDNLLLDARGHLKLSDFGLCTGLKKSHRTDFYR-DLSQAKPSDFIGTCAS 267
Query: 348 SMDDRRRMYNKLREEEVRYAHSTVGSPDYMALEVLEAKNYDFTVDYWSLGCILFESLVGY 407
MD +RR + R A+STVG+PDY+A EV Y D+WSLG I++E L+GY
Sbjct: 268 PMDSKRRAESWKRNRRA-LAYSTVGTPDYIAPEVFLQTGYGPACDWWSLGVIMYEMLMGY 326
Query: 408 TPFSGNSTNETYENLRNWKHVLQRPKCDNGRYAFSDRTWELITRLIADPINRL---KSFE 464
PF ++ +TY + NW+ L P S+ E I + RL + E
Sbjct: 327 PPFCSDNPQDTYRKVMNWRETLIFPP----EIPISEEAKETIINFCCEADRRLGSQRGLE 382
Query: 465 HVKRMRYFSEIDFNTLRTIHPPFIP-QLDNEEDVGYFDDF 503
+K + +F +D+ +R P IP ++ + +D FD+F
Sbjct: 383 DLKSVPFFRGVDWEHIRE-RPAAIPVEVRSIDDTSNFDEF 421
>YNL161w [R] KOG0605 NDR and related serine/threonine kinases
Length = 756
Score = 224 bits (570), Expect = 4e-58
Identities = 141/459 (30%), Positives = 219/459 (46%), Gaps = 32/459 (6%)
Query: 108 DYYCDMFDYVISRRERTRQVINYLEEQRRSNLMGTEQITNEWQGYLTKETNILRKRRLKP 167
++Y Y I R ER + LE + S+ E+ + + KE+ LR RR +
Sbjct: 292 NFYQSSVKYAIERNERRVE----LETELTSHNWSEERKSRQLSSLGKKESQFLRLRRTRL 347
Query: 168 KHKDFEMITXXXXXXXXXXXLARKKDTKEICAXXXXXXXXXXXXEGTDHVLTERDILTTT 227
+DF + L +KKDT +I A + HV ERD+L +
Sbjct: 348 SLEDFHTVKVIGKGAFGEVRLVQKKDTGKIYAMKTLLKSEMYKKDQLAHVKAERDVLAGS 407
Query: 228 RSEWLVKLLYAFQDPQSLYLAMEFVPGGDFRTLLLNTKFLQAPHARFYISEMFCAVNALH 287
S W+V L Y+FQD Q LYL MEF+PGGD T+L+ + RFY++E A+ +H
Sbjct: 408 DSPWVVSLYYSFQDAQYLYLIMEFLPGGDLMTMLIRWQLFTEDVTRFYMAECILAIETIH 467
Query: 288 QLGYTHRDLKPENFLIDSKGHIKLTDFGLASGTVSMERIESMKIRLQE---VKNLEFPEF 344
+LG+ HRD+KP+N LID +GHIKL+DFGL++G K LQ+ + P
Sbjct: 468 KLGFIHRDIKPDNILIDIRGHIKLSDFGLSTGFHKTHDSNYYKKLLQQDEATNGISKPGT 527
Query: 345 RERSMDD------------------RRRMYNKLREEEVRYAHSTVGSPDYMALEVLEAKN 386
+ D R+ R+ A+STVG+PDY+A E+ +
Sbjct: 528 YNANTTDTANKRQTMVVDSISLTMSNRQQIQTWRKSRRLMAYSTVGTPDYIAPEIFLYQG 587
Query: 387 YDFTVDYWSLGCILFESLVGYTPFSGNSTNETYENLRNWKHVLQRPKCDNGRYAFSDRTW 446
Y D+WSLG I++E L+G+ PF + ETY + N++ LQ P + Y D
Sbjct: 588 YGQECDWWSLGAIMYECLIGWPPFCSETPQETYRKIMNFEQTLQFPDDIHISYEAEDLIR 647
Query: 447 ELITRLIADP-INRLKSFEHVKRMRYFSEIDFNTLRTIHPPFIPQLDNEEDVGYF--DDF 503
L+T AD + R + +K +F +D+NT+R + P+IP+L + D +F D+
Sbjct: 648 RLLTH--ADQRLGRHGGADEIKSHPFFRGVDWNTIRQVEAPYIPKLSSITDTRFFPTDEL 705
Query: 504 TNEEHMARYVDVFKRQDRLTAMVDDS--LSDSKLVGFTF 540
N K+++++T + D +G+T+
Sbjct: 706 ENVPDSPAMAQAAKQREQMTKQGGSAPVKEDLPFIGYTY 744
>7301980 [D] KOG0608 Warts/lats-like serine threonine kinases
Length = 1105
Score = 221 bits (564), Expect = 2e-57
Identities = 143/434 (32%), Positives = 218/434 (49%), Gaps = 14/434 (3%)
Query: 80 KKLPKDFYKKSSKTKSKRLVSVCQMYFLDYYCDMFDYVISRRERTRQVINYLEEQRRSNL 139
KK+ K+ ++ + + ++ +F++ + + + + S R+RT + +E + L
Sbjct: 630 KKISKEKEEERKEFRIRQYSPQAFKFFMEQHIE--NVIKSYRQRTYRKNQLEKEMHKVGL 687
Query: 140 MGTEQITNEWQGYLT-KETNILRKRRLKPKHKDFEMITXXXXXXXXXXXLARKKDTKE-I 197
QI E + L KE+N +R +R K F + L K DT +
Sbjct: 688 PDQTQI--EMRKMLNQKESNYIRLKRAKMDKSMFVKLKPIGVGAFGEVTLVSKIDTSNHL 745
Query: 198 CAXXXXXXXXXXXXEGTDHVLTERDILTTTRSEWLVKLLYAFQDPQSLYLAMEFVPGGDF 257
A HV ERDIL + W+VKL Y+FQD +LY M+++PGGD
Sbjct: 746 YAMKTLRKADVLKRNQVAHVKAERDILAEADNNWVVKLYYSFQDKDNLYFVMDYIPGGDL 805
Query: 258 RTLLLNTKFLQAPHARFYISEMFCAVNALHQLGYTHRDLKPENFLIDSKGHIKLTDFGLA 317
+LL+ + ARFYI+E+ CAV+++H++G+ HRD+KP+N LID GHIKLTDFGL
Sbjct: 806 MSLLIKLGIFEEELARFYIAEVTCAVDSVHKMGFIHRDIKPDNILIDRDGHIKLTDFGLC 865
Query: 318 SG---TVSMERIESMKIRLQEVKNLEFPEFRERSMDDRRRMYNKLREEEVRYAHSTVGSP 374
+G T + + + ++ + E+ E ++R+ + AHS VG+P
Sbjct: 866 TGFRWTHNSKYYQENGNHSRQDSMEPWEEYSENGPKPTVLERRRMRDHQRVLAHSLVGTP 925
Query: 375 DYMALEVLEAKNYDFTVDYWSLGCILFESLVGYTPFSGNSTNETYENLRNWKHVLQRPKC 434
+Y+A EVLE Y DYWS+G IL+E LVG PF NS ET + + NW+ L P
Sbjct: 926 NYIAPEVLERSGYTQLCDYWSVGVILYEMLVGQPPFLANSPLETQQKVINWEKTLHIPP- 984
Query: 435 DNGRYAFSDRTWELITRLIADPINRL-KSFEHVKRMRYFSEIDFNTLRTIHPPFIPQLDN 493
+ S +LI RL A RL KS + VK +F IDF +R P+IP++ +
Sbjct: 985 ---QAELSREATDLIRRLCASADKRLGKSVDEVKSHDFFKGIDFADMRKQKAPYIPEIKH 1041
Query: 494 EEDVGYFDDFTNEE 507
D FD E+
Sbjct: 1042 PTDTSNFDPVDPEK 1055
>At5g09890 [R] KOG0605 NDR and related serine/threonine kinases
Length = 495
Score = 211 bits (537), Expect = 2e-54
Identities = 139/461 (30%), Positives = 227/461 (49%), Gaps = 27/461 (5%)
Query: 91 SKTKSKRLVSVCQMYFLDYYCDMFDYVISRRERTRQVINYLEEQRRSNLMGTEQITNEWQ 150
S +++ + + + ++Y + + R ER R+ ++E + + E+ +
Sbjct: 25 SSPVTRQKAAAAKQFIENHYKNYLQGLHERMERRREFQRKVQEAQ----LPVEEQDEMMR 80
Query: 151 GYLTKETNILRKRRLKPKHKDFEMITXXXXXXXXXXXLARKKDTKEICAXXXXXXXXXXX 210
+ET +R +R K DFE++T L R + T E+ A
Sbjct: 81 NLARRETEYMRLQRRKIGIDDFELLTVIGKGAFGEVRLCRLRSTSEVYAMKKLKKTEMLS 140
Query: 211 XEGTDHVLTERDILTTTRSEWLVKLLYAFQDPQSLYLAMEFVPGGDFRTLLLNTKFLQAP 270
+HV +ER++L S ++VKL Y+FQD + LYL ME++PGGD TLL+ L
Sbjct: 141 RGQVEHVRSERNLLAEVDSRYIVKLFYSFQDSECLYLIMEYLPGGDIMTLLMREDILSED 200
Query: 271 HARFYISEMFCAVNALHQLGYTHRDLKPENFLIDSKGHIKLTDFGLASGTVSMERIESMK 330
ARFYI+E A++++HQ Y HRD+KP+N ++D GH+KL+DFGL ++ S+
Sbjct: 201 VARFYIAESILAIHSIHQHNYVHRDIKPDNLILDKSGHLKLSDFGLCKPL--DDKYSSLL 258
Query: 331 IRLQEVKNLEFPEFRERSMDDRRRMYNKLREEEVRY-------AHSTVGSPDYMALEVLE 383
+ E+ + + E + D + + +E+ +++ A+STVG+ DYMA EVL
Sbjct: 259 LEDDEMLSQD-SENQSGKSDADKAPWQMPKEQLLQWKRNRRALAYSTVGTLDYMAPEVLL 317
Query: 384 AKNYDFTVDYWSLGCILFESLVGYTPFSGNSTNETYENLRNWKHVLQRPKCDNGRYAFSD 443
K Y D+WSLG IL+E LVGY PF + T + NW+ L+ P+ SD
Sbjct: 318 KKGYGMECDWWSLGAILYEMLVGYPPFCSDDPRITCRKIINWRVCLKFPE----EPKISD 373
Query: 444 RTWELITRLIADPINRL--KSFEHVKRMRYFSEIDFNTLRTIHPPFIPQLDNEEDVGYFD 501
+LI RL+ D +RL + E +K +F ++ L + + P +D E D F+
Sbjct: 374 EARDLICRLLCDVDSRLGTRGVEEIKSHPWFKGTPWDKLYDMEAAYRPIVDGELDTQNFE 433
Query: 502 DFTN-EEHMARYVDVFKRQDRLTAMVDDSLSDSKLVGFTFR 541
F E + V + LT+ D+ +GFTF+
Sbjct: 434 KFPEVEGSPSEAPQVGPWRKMLTS------KDTNFIGFTFK 468
>CE13844 [D] KOG0608 Warts/lats-like serine threonine kinases
Length = 908
Score = 209 bits (531), Expect = 1e-53
Identities = 139/435 (31%), Positives = 208/435 (46%), Gaps = 34/435 (7%)
Query: 94 KSKRLVSVCQMYFLDYYCDMFDYVISRRERTRQVINYLEEQRRSNLMGTEQIT------- 146
K+ R V C+ L +Y + ER Q Y E ++R + E ++
Sbjct: 423 KNTRRVQPCKPNMLRFYMEQ------HVERLLQ--QYKEREKRMKQLEKEMVSAQLPDIM 474
Query: 147 -NEWQGYLT-KETNILRKRRLKPKHKDFEMITXXXXXXXXXXXLARKKDTKEICAXXXXX 204
N+ G L KE+ R RR K F +I+ L RK DT+++ A
Sbjct: 475 RNKMLGLLQQKESKYTRLRRQKMSKSHFTVISHIGVGAFGKVSLVRKNDTRKVYAMKSLE 534
Query: 205 XXXXXXXEGTDHVLTERDILTTTRSEWLVKLLYAFQDPQSLYLAMEFVPGGDFRTLLLNT 264
+ HV ERDIL S W+V+L ++FQD LY ME+VPGGD TLL+
Sbjct: 535 KADVIMKQQAAHVKAERDILAEADSPWIVRLFFSFQDDACLYFIMEYVPGGDMMTLLIQK 594
Query: 265 KFLQAPHARFYISEMFCAVNALHQLGYTHRDLKPENFLIDSKGHIKLTDFGLASGT--VS 322
+ ARFYI+E+ CA+ +H +G+ HRDLKP+N LID GHIKLTDFGL +G
Sbjct: 595 GIFEEDLARFYIAELACAIEYVHNVGFIHRDLKPDNILIDQHGHIKLTDFGLCTGLRWTH 654
Query: 323 MERIESMKIRLQEVKNLEFPEFRERSMDDRRRMYNKLREEEVRYAHSTVGSPDYMALEVL 382
R + V + P ++D ++ N ++ AHS VG+ +YMA EV+
Sbjct: 655 DRRYYGPENDHHRVDSFSLPP-EVAAIDKSVKVLNVRQQTRRITAHSLVGTGNYMAPEVI 713
Query: 383 EAKNYDFTVDYWSLGCILFESLVGYTPFSGNSTNETYENLRNWKHVLQRPKCDNGRYAFS 442
++ + D+WS G IL+E + G PF ++ T ++NW++ L C N S
Sbjct: 714 AKTGHNQSCDWWSTGVILYEMVFGRVPFHDDTPGGTQHRIKNWRNFLDFTYCGN----LS 769
Query: 443 DRTWELITRLIADPINRLKSF--------EHVKRMRYFSEIDFNTLRTIHPP--FIPQLD 492
+I +LI D +RL S VK +F ID+ LR + +IP++
Sbjct: 770 KECLMMIQQLICDASSRLGSHGKDVAERTAQVKNHPWFRGIDWVNLRKLRADYIYIPRVT 829
Query: 493 NEEDVGYFDDFTNEE 507
++ED F+ F + +
Sbjct: 830 HDEDTSNFETFQDND 844
>Hs4758666 [D] KOG0608 Warts/lats-like serine threonine kinases
Length = 1130
Score = 205 bits (522), Expect = 1e-52
Identities = 145/461 (31%), Positives = 218/461 (46%), Gaps = 16/461 (3%)
Query: 51 SIVKNPENSLMDIDDDTQGDLTADITKSPKKLPKDFYKKSSKTKSKRLVSVCQMYFLDYY 110
S+ K E+ + D+ IT SP + K+ KK + + R+ S F +
Sbjct: 586 SLPKEDESEKSYENVDSGDKEKKQITTSPITVRKN--KKDEERRESRIQSYSPQAFKFFM 643
Query: 111 CDMFDYVISRRERTRQVINYLEEQRRSNLMGTEQITNEWQGYLTKETNILRKRRLKPKHK 170
+ V+ ++ LE + + + + KE+N +R +R K
Sbjct: 644 EQHVENVLKSHQQRLHRKKQLENEMMRVGLSQDAQDQMRKMLCQKESNYIRLKRAKMDKS 703
Query: 171 DFEMITXXXXXXXXXXXLARKKDTKEICAXXXXXXXXXXXXEGTDHVLTERDILTTTRSE 230
F I LARK DTK + A HV ERDIL +E
Sbjct: 704 MFVKIKTLGIGAFGEVCLARKVDTKALYATKTLRKKDVLLRNQVAHVKAERDILAEADNE 763
Query: 231 WLVKLLYAFQDPQSLYLAMEFVPGGDFRTLLLNTKFLQAPHARFYISEMFCAVNALHQLG 290
W+V+L Y+FQD +LY M+++PGGD +LL+ ARFYI+E+ CAV ++H++G
Sbjct: 764 WVVRLYYSFQDKDNLYFVMDYIPGGDMMSLLIRMGIFPESLARFYIAELTCAVESVHKMG 823
Query: 291 YTHRDLKPENFLIDSKGHIKLTDFGLASG---TVSMERIESMKIRLQEVKNL--EFPEFR 345
+ HRD+KP+N LID GHIKLTDFGL +G T + +S Q+ + E+ +
Sbjct: 824 FIHRDIKPDNILIDRDGHIKLTDFGLCTGFRWTHDSKYYQSGDHPRQDSMDFSNEWGDPS 883
Query: 346 ERSMDDRRRMYNK--LREEEVRYAHSTVGSPDYMALEVLEAKNYDFTVDYWSLGCILFES 403
DR + + R+ + AHS VG+P+Y+A EVL Y D+WS+G ILFE
Sbjct: 884 SCRCGDRLKPLERRAARQHQRCLAHSLVGTPNYIAPEVLLRTGYTQLCDWWSVGVILFEM 943
Query: 404 LVGYTPFSGNSTNETYENLRNWKHVLQRPKCDNGRYAFSDRTWELITRLIADPINRL--K 461
LVG PF + ET + NW+ L P + S +LI +L P +RL
Sbjct: 944 LVGQPPFLAQTPLETQMKVINWQTSLHIPP----QAKLSPEASDLIIKLCRGPEDRLGKN 999
Query: 462 SFEHVKRMRYFSEIDFNT-LRTIHPPFIPQLDNEEDVGYFD 501
+ +K +F IDF++ LR +IP++ + D FD
Sbjct: 1000 GADEIKAHPFFKTIDFSSDLRQQSASYIPKITHPTDTSNFD 1040
>Hs18959200 [D] KOG0608 Warts/lats-like serine threonine kinases
Length = 1088
Score = 204 bits (519), Expect = 3e-52
Identities = 144/454 (31%), Positives = 222/454 (48%), Gaps = 22/454 (4%)
Query: 66 DTQGDLTADITKSP---KKLPKDFYKKSSKTKSKRLVSVCQMYFLDYYCDMFDYVISRRE 122
D G I SP +K +D K+ S+ KS + +F++ + + + + + ++
Sbjct: 564 DKGGKDKKQIQTSPVPVRKNSRDEEKRESRIKSYSPYAF--KFFMEQHVE--NVIKTYQQ 619
Query: 123 RTRQVINYLEEQRRSNLMGTEQITNEWQGYLTKETNILRKRRLKPKHKDFEMITXXXXXX 182
+ + + +E ++ L EQ Y KE+N R +R K F I
Sbjct: 620 KVNRRLQLEQEMAKAGLCEAEQEQMRKILY-QKESNYNRLKRAKMDKSMFVKIKTLGIGA 678
Query: 183 XXXXXLARKKDTKEICAXXXXXXXXXXXXEGTDHVLTERDILTTTRSEWLVKLLYAFQDP 242
LA K DT + A HV ERDIL +EW+VKL Y+FQD
Sbjct: 679 FGEVCLACKVDTHALYAMKTLRKKDVLNRNQVVHVKAERDILAEADNEWVVKLYYSFQDK 738
Query: 243 QSLYLAMEFVPGGDFRTLLLNTKFLQAPHARFYISEMFCAVNALHQLGYTHRDLKPENFL 302
SLY M+++PGGD +LL+ + ARFYI+E+ A+ ++H++G+ HRD+KP+N L
Sbjct: 739 DSLYFVMDYIPGGDMMSLLIRMEVFPEHLARFYIAELTLAIESVHKMGFIHRDIKPDNIL 798
Query: 303 IDSKGHIKLTDFGLASG------TVSMERIESMKIRLQEVKNLEFPEFRERSMDDRRRMY 356
ID GHIKLTDFGL +G + ++ ++ E +L R D + +
Sbjct: 799 IDLDGHIKLTDFGLCTGFRWTHNSKYYQKGSHVRQDSMEPSDLWDDVSNCRCGDRLKTLE 858
Query: 357 NKLREEEVR-YAHSTVGSPDYMALEVLEAKNYDFTVDYWSLGCILFESLVGYTPFSGNST 415
+ R++ R AHS VG+P+Y+A EVL K Y D+WS+G ILFE LVG PF +
Sbjct: 859 QRARKQHQRCLAHSLVGTPNYIAPEVLLRKGYTQLCDWWSVGVILFEMLVGQPPFLAPTP 918
Query: 416 NETYENLRNWKHVLQRPKCDNGRYAFSDRTWELITRLIADPINRL--KSFEHVKRMRYFS 473
ET + NW++ L P + S +LIT+L +RL + +K +FS
Sbjct: 919 TETQLKVINWENTLHIP----AQVKLSPEARDLITKLCCSADHRLGRNGADDLKAHPFFS 974
Query: 474 EIDFNT-LRTIHPPFIPQLDNEEDVGYFDDFTNE 506
IDF++ +R P++P + + D FD E
Sbjct: 975 AIDFSSDIRKQPAPYVPTISHPMDTSNFDPVDEE 1008
>At3g23310 [R] KOG0605 NDR and related serine/threonine kinases
Length = 568
Score = 204 bits (518), Expect = 4e-52
Identities = 142/482 (29%), Positives = 230/482 (47%), Gaps = 29/482 (6%)
Query: 76 TKSPKKLPKDFYKKSSKTK---------SKRLVSVCQMYFLDYYCDMFDYVISRRERTRQ 126
+ + K+ + K+ SKT +K+ + + Y ++Y R+ER
Sbjct: 19 SSNKKETSRGNVKEGSKTAGGEEAVSNVTKQKAAAAKQYIENHYKKQVQSQQQRKERR-- 76
Query: 127 VINYLEEQRRSNLMGTEQITNEWQGYLTKETNILRKRRLKPKHKDFEMITXXXXXXXXXX 186
+ LE + + + E+ N + KET +R++R K DFE +T
Sbjct: 77 --DMLENKLAAAEVSEEEQKNLLKDLEKKETEYMRRQRHKMGTDDFEPLTMIGKGAFGEV 134
Query: 187 XLARKKDTKEICAXXXXXXXXXXXXEGTDHVLTERDILTTTRSEWLVKLLYAFQDPQSLY 246
+ R+K T + A +HV ER++L S +VKL +FQD + LY
Sbjct: 135 RICREKTTGNVYAMKKLKKSEMLRRGQVEHVKAERNLLAEVDSNCIVKLYCSFQDEEYLY 194
Query: 247 LAMEFVPGGDFRTLLLNTKFLQAPHARFYISEMFCAVNALHQLGYTHRDLKPENFLIDSK 306
L ME++PGGD TLL+ L ARFY+ E A+ ++H+ Y HRD+KP+N L+D
Sbjct: 195 LIMEYLPGGDMMTLLMRKDTLTEDEARFYVGETVLAIESIHKHNYIHRDIKPDNLLLDRS 254
Query: 307 GHIKLTDFGLASG---TVSMERIESMKIRLQ-EVKNLEFPEFRERSMDDRRRMYNKLREE 362
GH+KL+DFGL ++ E+ + L +++ P R+ ++ N R
Sbjct: 255 GHMKLSDFGLCKPLDCSILQEKDFVVAHNLSGALQSDGRPVAPRRTRSQMEQLQNWQRNR 314
Query: 363 EVRYAHSTVGSPDYMALEVLEAKNYDFTVDYWSLGCILFESLVGYTPFSGNSTNETYENL 422
+ A+STVG+PDY+A EVL K Y D+WSLG I++E LVG+ PF + T +
Sbjct: 315 RM-LAYSTVGTPDYIAPEVLLKKGYGMECDWWSLGAIMYEMLVGFPPFYSDEPMTTCRKI 373
Query: 423 RNWKHVLQRPKCDNGRYAFSDRTWELITRLIADPINRL--KSFEHVKRMRYFSEIDFNTL 480
NWK+ L+ P S +LI RL+ + R+ K +K +FS +++ L
Sbjct: 374 VNWKNYLKFP----DEVRLSPEAKDLICRLLCNVEQRIGTKGANEIKEHPWFSGVEWEKL 429
Query: 481 RTIHPPFIPQLDNEEDVGYFDDFTNEEHMARYVDVFKRQDRLTAMVDDSLSDSKLVGFTF 540
+ FIPQ+++E D F+ F E + + + M+ S D VG+T+
Sbjct: 430 YQMKAAFIPQVNDELDTQNFEKF---EEVKTKIPKTPKSGPWRKML--SSKDINFVGYTY 484
Query: 541 RH 542
++
Sbjct: 485 KN 486
>At4g33080 [R] KOG0605 NDR and related serine/threonine kinases
Length = 483
Score = 203 bits (516), Expect = 6e-52
Identities = 140/471 (29%), Positives = 229/471 (47%), Gaps = 26/471 (5%)
Query: 90 SSKTKSKRLVSVCQMYFLDYYCDMFDYVISRRERTRQVINYLEEQRRSNLMGTEQITNEW 149
SS T K V+ + Y ++Y + R+ER LE + S+ + E+ N
Sbjct: 18 SSLTMEK--VAAAKQYIENHYKAQNKNIQERKERRW----ILERKLASSGVPKEEQINMI 71
Query: 150 QGYLTKETNILRKRRLKPKHKDFEMITXXXXXXXXXXXLARKKDTKEICAXXXXXXXXXX 209
+ KET +R +R K DFE++T L R++ + I A
Sbjct: 72 KDLERKETEFMRLKRNKISVDDFELLTIIGRGAFGEVRLCRERKSGNIYAMKKLKKSEMV 131
Query: 210 XXEGTDHVLTERDILTTTRSEWLVKLLYAFQDPQSLYLAMEFVPGGDFRTLLLNTKFLQA 269
+HV ER++L S ++VKL Y+FQDP+ LYL ME++PGGD TLL+ L+
Sbjct: 132 MRGQVEHVRAERNLLAEVESHYIVKLYYSFQDPEYLYLIMEYLPGGDMMTLLMREDTLRE 191
Query: 270 PHARFYISEMFCAVNALHQLGYTHRDLKPENFLIDSKGHIKLTDFGLASGTVSMERIESM 329
ARFYI++ A+ ++H+ Y HRD+KP+N L+D GH+KL+DFGL
Sbjct: 192 DVARFYIAQSVLAIESIHRYNYIHRDIKPDNLLLDKDGHMKLSDFGLCKPLDCRNLPSIQ 251
Query: 330 KIRLQEVKNLEFPEFRERSM--DDRRRMYNKLREE-------EVRYAHSTVGSPDYMALE 380
+ R + + + P +R D +R + +E+ + A STVG+PDY+A E
Sbjct: 252 ENRATDDETMSEPMDVDRCFPDTDNKRSWRSPQEQLQHWQMNRRKLAFSTVGTPDYIAPE 311
Query: 381 VLEAKNYDFTVDYWSLGCILFESLVGYTPFSGNSTNETYENLRNWKHVLQRPKCDNGRYA 440
VL K Y D+WSLG I++E LVGY PF + T + +W++ L+ P+
Sbjct: 312 VLLKKGYGMECDWWSLGAIMYEMLVGYPPFYADDPISTCRKIVHWRNHLKFPE----DAK 367
Query: 441 FSDRTWELITRLIADPINRLKS---FEHVKRMRYFSEIDFNTLRTIHPPFIPQLDNEEDV 497
FS +LI RL+ + +RL + + +K +F ++ + L + + P++++E D
Sbjct: 368 FSSEAKDLICRLLCNVDHRLGTGGGAQQIKDHPWFKDVVWEKLYEMEAAYKPEVNDELDT 427
Query: 498 GYFDDFTNEEHMARYVDVFKRQDRLTAMVDDSLSDSKLVGFTFRHRNGKDG 548
F F A + + L+ + + D VG+T+++ + G
Sbjct: 428 QNFMKFDEVNSPAPE----RTRSGLSRKMLLAPKDLSFVGYTYKNFDAVKG 474
>At1g30640 [R] KOG0605 NDR and related serine/threonine kinases
Length = 562
Score = 202 bits (515), Expect = 8e-52
Identities = 137/462 (29%), Positives = 220/462 (46%), Gaps = 26/462 (5%)
Query: 90 SSKTKSKRLVSVCQMYFLDYYCDMFDYVISRRERTRQVINYLEEQRRSNLMGTEQITNEW 149
S+ TK K V+ + Y ++Y + R+ER + LE+ + E +
Sbjct: 44 SNATKQK--VAAAKQYIENHYKIQKKSLQERKERR----SILEQNLADADVTVEDKMDIL 97
Query: 150 QGYLTKETNILRKRRLKPKHKDFEMITXXXXXXXXXXXLARKKDTKEICAXXXXXXXXXX 209
+ + KE +R +R K DFE+++ + ++K T + A
Sbjct: 98 KNFEKKEMEYMRLQRQKMGVDDFELLSIIGRGAFGEVRICKEKSTGSVYAMKKLKKSEML 157
Query: 210 XXEGTDHVLTERDILTTTRSEWLVKLLYAFQDPQSLYLAMEFVPGGDFRTLLLNTKFLQA 269
+HV ER++L S ++VKL Y+FQD + LYL ME++PGGD TLL+ L+
Sbjct: 158 RRGQVEHVKAERNVLAEVDSPFIVKLCYSFQDDEHLYLIMEYLPGGDMMTLLMRKDTLRE 217
Query: 270 PHARFYISEMFCAVNALHQLGYTHRDLKPENFLIDSKGHIKLTDFGLASGTVS------- 322
RFY+++ A+ ++H+ Y HRD+KP+N LI GHIKL+DFGL+ S
Sbjct: 218 DETRFYVAQTILAIESIHKHNYVHRDIKPDNLLITRNGHIKLSDFGLSKSLESKNFPDFK 277
Query: 323 MERIESMKIRLQEVKNLEFPEFRERSMDDRRRMYNKLREEEVRYAHSTVGSPDYMALEVL 382
E ++ E L P R + ++ ++ A STVG+PDY+A EVL
Sbjct: 278 AELVDRSTKPAAEHDRLSKPPSAPRRTQQEQLLH--WQQNRRTLAFSTVGTPDYIAPEVL 335
Query: 383 EAKNYDFTVDYWSLGCILFESLVGYTPFSGNSTNETYENLRNWKHVLQRPKCDNGRYAFS 442
K Y D+WSLG I+FE LVG+ PF T + NWK L+ P D + +
Sbjct: 336 LKKGYGMECDWWSLGAIMFEMLVGFPPFYSEEPLATCRKIVNWKTCLKFP--DEAKLSIE 393
Query: 443 DRTWELITRLIADPINRL--KSFEHVKRMRYFSEIDFNTLRTIHPPFIPQLDNEEDVGYF 500
+ +LI RL+ + RL K +K +F +++ L + P+IPQ+ +E D F
Sbjct: 394 VK--DLIRRLLCNVEQRLGTKGVHEIKAHPWFRGVEWERLYESNAPYIPQVKHELDTQNF 451
Query: 501 DDFTNEEHMARYVDVFKRQDRLTAMVDDSLSDSKLVGFTFRH 542
+ F + + + M+ S D+ +G+TF++
Sbjct: 452 EKF---DEVPSTCQTSSKSSPWRKMI--SSKDANFLGYTFKN 488
>At2g20470 [R] KOG0605 NDR and related serine/threonine kinases
Length = 596
Score = 201 bits (512), Expect = 2e-51
Identities = 131/426 (30%), Positives = 211/426 (48%), Gaps = 25/426 (5%)
Query: 90 SSKTKSKRLVSVCQMYFLDYYCDMFDYVISRRERTRQVINYLEEQRRSNLMGTEQITNEW 149
S+ TK K V+ + Y ++Y + + R+ER + EQ+ ++ +E+ N
Sbjct: 48 SNTTKQK--VAAAKQYIENHYKEQMKILQERKERRSML-----EQKLADADVSEEDQNNL 100
Query: 150 QGYLTK-ETNILRKRRLKPKHKDFEMITXXXXXXXXXXXLARKKDTKEICAXXXXXXXXX 208
+L K ET +R +R K DF+++T + R+K T ++ A
Sbjct: 101 LKFLEKKETEYMRLQRHKLGVADFDLLTMIGKGAFGEVRVCREKTTGQVYAMKKLKKAEM 160
Query: 209 XXXEGTDHVLTERDILTTTRSEWLVKLLYAFQDPQSLYLAMEFVPGGDFRTLLLNTKFLQ 268
+HV ER++L S ++VKL +FQD LYL ME++PGGD TLL+ L
Sbjct: 161 LRRGQVEHVRAERNLLAEVDSNYIVKLYCSFQDDDHLYLVMEYLPGGDMMTLLMRKDTLT 220
Query: 269 APHARFYISEMFCAVNALHQLGYTHRDLKPENFLIDSKGHIKLTDFGLASGTVSMERIES 328
A+FY++E A+ ++H+ Y HRD+KP+N L+D GH++L+DFGL + ++
Sbjct: 221 EEEAKFYVAETVLAIESIHRHNYIHRDIKPDNLLLDRYGHLRLSDFGLC------KPLDC 274
Query: 329 MKIRLQEVKNLE--FPEFRERSMDDRRRMYNKL---REEEVRYAHSTVGSPDYMALEVLE 383
I + N E S +R +L + A+STVG+PDY+A EVL
Sbjct: 275 SAIGENDFSNNSNGSTEQEAGSTAPKRTQQEQLEHWQRNRRTLAYSTVGTPDYIAPEVLL 334
Query: 384 AKNYDFTVDYWSLGCILFESLVGYTPFSGNSTNETYENLRNWKHVLQRPKCDNGRYAFSD 443
K Y D+WSLG I++E LVGY PF + T + NWK L+ P+ S
Sbjct: 335 KKGYGMECDWWSLGAIMYEMLVGYPPFYSDDPMSTCRKIVNWKSHLKFPE----EAILSR 390
Query: 444 RTWELITRLIADPINRL--KSFEHVKRMRYFSEIDFNTLRTIHPPFIPQLDNEEDVGYFD 501
+LI L+ RL K + +K +F +D++T+ + F+P+++++ D F+
Sbjct: 391 EAKDLINSLLCSVRRRLGSKGADELKAHTWFETVDWDTIFDMDAAFVPEVNDDLDTQNFE 450
Query: 502 DFTNEE 507
F E
Sbjct: 451 KFDESE 456
>At1g03920 [R] KOG0605 NDR and related serine/threonine kinases
Length = 569
Score = 196 bits (499), Expect = 6e-50
Identities = 146/480 (30%), Positives = 229/480 (47%), Gaps = 26/480 (5%)
Query: 69 GDLTADITKSPKKLPKDFYKKSSKTKSKRLVSVCQMYFLDYYCDMFDYVISRRERTRQVI 128
G+ T TK P L D S+ TK K V+ + Y ++Y + + R+ER
Sbjct: 41 GNDTETATKLPP-LGGDGEALSNSTKQK--VAAAKQYIENHYKEQMKNLNERKERRTT-- 95
Query: 129 NYLEEQRRSNLMGTEQITNEWQGYLTKETNILRKRRLKPKHKDFEMITXXXXXXXXXXXL 188
LE++ + E TN + KET +R +R K DFE++T +
Sbjct: 96 --LEKKLADADVCEEDQTNLMKFLEKKETEYMRLQRHKMGADDFELLTMIGKGAFGEVRV 153
Query: 189 ARKKDTKEICAXXXXXXXXXXXXEGTDHVLTERDILTTTRSEWLVKLLYAFQDPQSLYLA 248
R+ +T + A +HV ER++L S +VKL +FQD + LYL
Sbjct: 154 VREINTGHVFAMKKLKKSEMLRRGQVEHVRAERNLLAEVDSNCIVKLYCSFQDNEYLYLI 213
Query: 249 MEFVPGGDFRTLLLNTKFLQAPHARFYISEMFCAVNALHQLGYTHRDLKPENFLIDSKGH 308
ME++PGGD TLL+ L A+FYI+E A+ ++H Y HRD+KP+N L+D GH
Sbjct: 214 MEYLPGGDMMTLLMRKDTLSEDEAKFYIAESVLAIESIHNRNYIHRDIKPDNLLLDRYGH 273
Query: 309 IKLTDFGLASGTVSMERIESMKIRLQEVKNLEFPE----FRERSMDDRRRMYNKLREEEV 364
++L+DFGL + I+ + + E +RS ++ + K R
Sbjct: 274 LRLSDFGLCK-PLDCSVIDGEDFTVGNAGSGGGSESVSTTPKRSQQEQLEHWQKNRR--- 329
Query: 365 RYAHSTVGSPDYMALEVLEAKNYDFTVDYWSLGCILFESLVGYTPFSGNSTNETYENLRN 424
A+STVG+PDY+A EVL K Y D+WSLG I++E LVGY PF + T + N
Sbjct: 330 MLAYSTVGTPDYIAPEVLLKKGYGMECDWWSLGAIMYEMLVGYPPFYADDPMSTCRKIVN 389
Query: 425 WKHVLQRPKCDNGRYAFSDRTWELITRLIADPINRLKS--FEHVKRMRYFSEIDFNTLRT 482
WK L+ P + R + R +LI +L+ RL S +K +F + + +
Sbjct: 390 WKTHLKFP--EESRLSRGAR--DLIGKLLCSVNQRLGSTGASQIKAHPWFEGVQWEKIYQ 445
Query: 483 IHPPFIPQLDNEEDVGYFDDFTNEEHMARYVDVFKRQDRLTAMVDDSLSDSKLVGFTFRH 542
+ FIP+++++ D F+ F E++ + R M+ S D VG+T+++
Sbjct: 446 MEAAFIPEVNDDLDTQNFEKFDEEDNQTQ---APSRTGPWRKML--SSKDINFVGYTYKN 500
>At4g14350 [R] KOG0605 NDR and related serine/threonine kinases
Length = 475
Score = 195 bits (496), Expect = 1e-49
Identities = 132/417 (31%), Positives = 200/417 (47%), Gaps = 16/417 (3%)
Query: 131 LEEQRRSNLMGTEQITNEWQGYLTKETNILRKRRLKPKHKDFEMITXXXXXXXXXXXLAR 190
LE++ + + E+ N + KET +R++R K DFE +T + R
Sbjct: 2 LEKKLAAAEVSEEEQNNLLKDLEMKETEYMRRQRHKMGADDFEPLTMIGKGAFGEVRICR 61
Query: 191 KKDTKEICAXXXXXXXXXXXXEGTDHVLTERDILTTTRSEWLVKLLYAFQDPQSLYLAME 250
+K T + A +HV ER++L S +VKL +FQD + LYL ME
Sbjct: 62 EKGTGNVYAMKKLKKSEMLRRGQVEHVKAERNLLAEVDSNCIVKLYCSFQDEEYLYLIME 121
Query: 251 FVPGGDFRTLLLNTKFLQAPHARFYISEMFCAVNALHQLGYTHRDLKPENFLIDSKGHIK 310
++PGGD TLL+ L ARFYI E A+ ++H+ Y HRD+KP+N L+D GH+K
Sbjct: 122 YLPGGDMMTLLMRKDTLTEDEARFYIGETVLAIESIHKHNYIHRDIKPDNLLLDKDGHMK 181
Query: 311 LTDFGLASGTVSMERIESMKIRLQEVKNLEFPEFRERSMDDRRRMYNKL---REEEVRYA 367
L+DFGL E + V + R + RR +L + A
Sbjct: 182 LSDFGLCKPLDCSNLQEKDFTVARNVSGA--LQSDGRPVATRRTQQEQLLNWQRNRRMLA 239
Query: 368 HSTVGSPDYMALEVLEAKNYDFTVDYWSLGCILFESLVGYTPFSGNSTNETYENLRNWKH 427
+STVG+PDY+A EVL K Y D+WSLG I++E LVG+ PF + T + NW++
Sbjct: 240 YSTVGTPDYIAPEVLLKKGYGMECDWWSLGAIMYEMLVGFPPFYSDDPMTTCRKIVNWRN 299
Query: 428 VLQRPKCDNGRYAFSDRTWELITRLIADPINRL--KSFEHVKRMRYFSEIDFNTLRTIHP 485
L+ P S +LI RL+ + RL K + +K +F ++ L +
Sbjct: 300 YLKFP----DEVRLSPEAKDLICRLLCNVEQRLGTKGADEIKGHPWFRGTEWGKLYQMKA 355
Query: 486 PFIPQLDNEEDVGYFDDFTNEEHMARYVDVFKRQDRLTAMVDDSLSDSKLVGFTFRH 542
FIPQ+++E D F+ F E + V + M+ S D VG+T+++
Sbjct: 356 AFIPQVNDELDTQNFEKF---EETDKQVPKSAKSGPWRKML--SSKDINFVGYTYKN 407
>At2g19400 [R] KOG0605 NDR and related serine/threonine kinases
Length = 545
Score = 192 bits (487), Expect = 1e-48
Identities = 135/424 (31%), Positives = 210/424 (48%), Gaps = 25/424 (5%)
Query: 99 VSVCQMYFLDYYCDMFDYVISRRERTRQVINYLEEQRRSNLMGTEQITNEW-QGYLTKET 157
V+ + Y ++Y ++ R+ER ++ EQ+ ++L +E+ E + KET
Sbjct: 36 VAAAKKYIENHYNRRMRHIQQRKER-----RWVLEQKIASLDVSEKEQLELLEDLQRKET 90
Query: 158 NILRKRRLKPKHKDFEMITXXXXXXXXXXXLARKKDTKEICAXXXXXXXXXXXXEGTDHV 217
R R + DF++++ L R+K T I A +HV
Sbjct: 91 EYTRLMRNRLCVDDFDLLSIIGRGAFGEVRLCREKKTGNIYAMKKLKKSEMLSRGQVEHV 150
Query: 218 LTERDILTTTRSEWLVKLLYAFQDPQSLYLAMEFVPGGDFRTLLLNTKFLQAPHARFYIS 277
ER++L S+ +VKL Y+FQDP+ LYL ME++ GGD TLL+ + L ARFYI+
Sbjct: 151 RAERNLLAEVASDCIVKLYYSFQDPEYLYLIMEYLSGGDVMTLLMREETLTETVARFYIA 210
Query: 278 EMFCAVNALHQLGYTHRDLKPENFLIDSKGHIKLTDFGLASGTVSMERIESMKIR--LQE 335
+ A+ ++H+ Y HRD+KP+N L+D GH+KL+DFGL + I +M + L +
Sbjct: 211 QSVLAIESIHKHNYVHRDIKPDNLLLDKYGHMKLSDFGLCK-PLDCRNISAMNVNEPLND 269
Query: 336 VKNLEFPEFRERSMDDRRRMYNKLREEEVRY--------AHSTVGSPDYMALEVLEAKNY 387
E + E RR K E++++ A+STVG+PDY+A EVL K Y
Sbjct: 270 ENINESIDGDENCSIGRRGRRWKSPLEQLQHWQINRRKLAYSTVGTPDYIAPEVLLKKGY 329
Query: 388 DFTVDYWSLGCILFESLVGYTPFSGNSTNETYENLRNWKHVLQRPKCDNGRYAFSDRTWE 447
D+WSLG I++E LVGY PF + T + +W+ L P + R R +
Sbjct: 330 GVECDWWSLGAIMYEMLVGYPPFYSDDPVTTCRKIVSWRTHLVFP--EGARLTPEAR--D 385
Query: 448 LITRLIADPINRLKSF----EHVKRMRYFSEIDFNTLRTIHPPFIPQLDNEEDVGYFDDF 503
LI RL+ D +RL S E +K +F ++++ L + F P ++ E D F F
Sbjct: 386 LICRLLCDSEHRLGSHGAGAEQIKAHTWFKDVEWEKLYEMDAAFKPVVNGELDTQNFMKF 445
Query: 504 TNEE 507
E
Sbjct: 446 DEVE 449
>At1g48490 [TR] KOG0606 Microtubule-associated serine/threonine kinase and
related proteins
Length = 1244
Score = 177 bits (449), Expect = 4e-44
Identities = 114/355 (32%), Positives = 176/355 (49%), Gaps = 30/355 (8%)
Query: 156 ETNILRKRRLKPKH-------KDFEMITXXXXXXXXXXXLARKKDTKEICAXXXXXXXXX 208
E +++R R P H DFE++ LARK T ++ A
Sbjct: 805 EDDVVRSLRTSPVHLRDRISIDDFEVMKSISRGAFGHVILARKNTTGDLFAIKVLRKADM 864
Query: 209 XXXEGTDHVLTERDILTTTRSEWLVKLLYAFQDPQSLYLAMEFVPGGDFRTLLLNTKFLQ 268
+ +L ERDIL R+ ++V+ Y+F ++LYL ME++ GGDF ++L L
Sbjct: 865 IRKNAVESILAERDILINARNPFVVRFFYSFTCSENLYLVMEYLNGGDFYSMLRKIGCLD 924
Query: 269 APHARFYISEMFCAVNALHQLGYTHRDLKPENFLIDSKGHIKLTDFGLASGTVSMERIES 328
+AR YI+E+ A+ LH G HRDLKP+N LI GH+KLTDFGL+ +
Sbjct: 925 EANARVYIAEVVLALEYLHSEGVVHRDLKPDNLLIAHDGHVKLTDFGLSKVGL------- 977
Query: 329 MKIRLQEVKNLEFPEFRERSMDDRRRMYNKLREEEVRYAHSTVGSPDYMALEVLEAKNYD 388
+ +L P S+ + K + + + S VG+PDY+A E+L +
Sbjct: 978 ----INNTDDLSGPVSSATSL----LVEEKPKLPTLDHKRSAVGTPDYLAPEILLGTGHG 1029
Query: 389 FTVDYWSLGCILFESLVGYTPFSGNSTNETYENLRNWKHVLQRPKCDNGRYAFSDRTWEL 448
T D+WS+G IL+E LVG PF+ + + ++N+ N +++ P ++ S +L
Sbjct: 1030 ATADWWSVGIILYEFLVGIPPFNADHPQQIFDNILN-RNIQWPPVPED----MSHEARDL 1084
Query: 449 ITRLIA-DPINRL--KSFEHVKRMRYFSEIDFNTLRTIHPPFIPQLDNEEDVGYF 500
I RL+ DP RL + VK+ +F +ID+NTL F+P +N D YF
Sbjct: 1085 IDRLLTEDPHQRLGARGAAEVKQHSFFKDIDWNTLAQQKAAFVPDSENAFDTSYF 1139
>At3g17850 [TR] KOG0606 Microtubule-associated serine/threonine kinase and
related proteins
Length = 1263
Score = 174 bits (441), Expect = 3e-43
Identities = 116/361 (32%), Positives = 172/361 (47%), Gaps = 36/361 (9%)
Query: 156 ETNILRKRRLKPKHK-------DFEMITXXXXXXXXXXXLARKKDTKEICAXXXXXXXXX 208
E +++R R P H DFE+I LA+K+ T ++ A
Sbjct: 867 EDDVVRSLRTSPVHPRDRTSIDDFEIIKPISRGAFGRVFLAKKRTTGDLFAIKVLKKADM 926
Query: 209 XXXEGTDHVLTERDILTTTRSEWLVKLLYAFQDPQSLYLAMEFVPGGDFRTLLLNTKFLQ 268
+ +L ERDIL R+ ++V+ Y+F +LYL ME++ GGD +LL N L+
Sbjct: 927 IRKNAVESILAERDILINVRNPFVVRFFYSFTCRDNLYLVMEYLNGGDLYSLLRNLGCLE 986
Query: 269 APHARFYISEMFCAVNALHQLGYTHRDLKPENFLIDSKGHIKLTDFGLASGTVSMERIES 328
R YI+E+ A+ LH G HRDLKP+N LI GHIKLTDFGL+ +
Sbjct: 987 EDIVRVYIAEVVLALEYLHSEGVVHRDLKPDNLLIAHDGHIKLTDFGLSKVGL------- 1039
Query: 329 MKIRLQEVKNLEFPEFRERSMDDRRRMYNKLREEEV--RYAHSTVGSPDYMALEVLEAKN 386
+ +L P S+ D EE++ R S VG+PDY+A E+L
Sbjct: 1040 ----INSTDDLAGPAVSGTSLLDEEESRLAASEEQLERRKKRSAVGTPDYLAPEILLGTG 1095
Query: 387 YDFTVDYWSLGCILFESLVGYTPFSGNSTNETYENLRN----WKHVLQRPKCDNGRYAFS 442
+ T D+WS+G ILFE +VG PF+ + ++N+ N W HV + S
Sbjct: 1096 HGATADWWSVGIILFELIVGIPPFNAEHPQQIFDNILNRKIPWPHVPEE---------MS 1146
Query: 443 DRTWELITR-LIADPINRL--KSFEHVKRMRYFSEIDFNTLRTIHPPFIPQLDNEEDVGY 499
++I R L DP RL + VK+ +F +I+++TL F+P ++ D Y
Sbjct: 1147 AEAHDIIDRFLTEDPHQRLGARGAAEVKQHIFFKDINWDTLARQKAAFVPASESAIDTSY 1206
Query: 500 F 500
F
Sbjct: 1207 F 1207
>7294566 [T] KOG0612 Rho-associated coiled-coil containing protein kinase
Length = 1252
Score = 172 bits (435), Expect = 2e-42
Identities = 132/470 (28%), Positives = 210/470 (44%), Gaps = 89/470 (18%)
Query: 91 SKTKSKRLVSVCQMYFLDYYCDMFDYVI--SRRERTRQVINYLEEQRRSNLMGTEQITNE 148
S T + ++C+ LD +C +++ + ++R R + ++ + R
Sbjct: 51 STTSAAVAEAICREGLLDAFCLLYNECDKDTLKKRDRNIAEFVNKFRP------------ 98
Query: 149 WQGYLTKETNILRKRRLKPKHKDFEMITXXXXXXXXXXXLARKKDTKEICAXXXXXXXXX 208
+ +ET R+L+ DF + T L ++ T +I A
Sbjct: 99 ----IIEET-----RKLRVNADDFLIKTLIGQGYFGNVHLVVERQTNDIYAMKKIKKSVV 149
Query: 209 XXXEGTDHVLTERDILTTTRSEWLVKLLYAFQDPQSLYLAMEFVPGGDFRTLLLNTKFLQ 268
T V ERDI++ SEWL+ L YAFQD +LYL ME++PGGD +L+
Sbjct: 150 T----TSQVKEERDIMSIRNSEWLINLQYAFQDNDNLYLVMEYMPGGDLLSLMSRHGPFD 205
Query: 269 APHARFYISEMFCAVNALHQLGYTHRDLKPENFLIDSKGHIKLTDFGLASGTVSMERIES 328
ARFY++E+ A++ LH++GY HRD+KPEN LID GHIKL DFG A+ + S
Sbjct: 206 EDLARFYLAELTVALHTLHEMGYVHRDIKPENILIDRFGHIKLADFGNAAALDRDGHVLS 265
Query: 329 MKIRLQEVKNLEFPEFRERSMDDRRRMYNKLREEEVRYAHSTVGSPDYMALEVLEA---- 384
+ S VG+PDY+A E+L+
Sbjct: 266 L---------------------------------------SPVGTPDYIAPELLQTISTY 286
Query: 385 ----KNYDFTVDYWSLGCILFESLVGYTPFSGNSTNETYENL------RNWKHVLQRPKC 434
+D + DYWS+G I +E + TPF ++ +ETY + + K ++ P
Sbjct: 287 KLSKSMHDVSCDYWSMGIIGYELICETTPFHEDNVHETYSKILSHCEESHLKELISFP-- 344
Query: 435 DNGRYAFSDRTWELITRLIADPINRLKSFEHVKRMRYFSEIDFNTLRTIHPPFIPQLDNE 494
S LI L+ +P RL S+E +K +FSEI + ++R+ PP IP + ++
Sbjct: 345 --ADLKVSVNYRNLIESLVTNPSKRL-SYERIKNHPFFSEIPWGSIRSQVPPIIPTVRSD 401
Query: 495 EDVGYFDDFTNEEHMARYVDVFKRQDRLTAMVDDSLS--DSKLVGFTFRH 542
+D F+D H R ++ T M + S D +G++F H
Sbjct: 402 DDTSNFED--GIRHKTRREQGVAKKSLTTNMKSNDFSGKDLPFIGYSFVH 449
>At5g62310 [TR] KOG0606 Microtubule-associated serine/threonine kinase and
related proteins
Length = 1168
Score = 169 bits (429), Expect = 8e-42
Identities = 143/498 (28%), Positives = 222/498 (43%), Gaps = 76/498 (15%)
Query: 65 DDTQGDLTADITKSPKKLPKDFYKKSSKT-----------------KSKRLVSVCQMYFL 107
D + G LT +P+ D KT +S V+VC L
Sbjct: 605 DSSAGSLTPPSPATPRNSQVDLLLSGRKTISELENYQQINKLLDIARSVANVNVCGYSSL 664
Query: 108 DYYCDMFD---YVISRRERTRQV-------INYLEEQRRSNLMG---------TEQITNE 148
D+ + D YVI R+ V I L +++ L G + + +E
Sbjct: 665 DFMIEQLDELKYVIQDRKADALVVETFGRRIEKLLQEKYIELCGLIDDEKVDSSNAMPDE 724
Query: 149 WQGYLTKETNILRKRRLKPKHKD------FEMITXXXXXXXXXXXLARKKDTKEICAXXX 202
LR L P+ KD FE+I LA+K+ T ++ A
Sbjct: 725 ESSADEDTVRSLRASPLNPRAKDRTSIEDFEIIKPISRGAFGRVFLAKKRATGDLFAIKV 784
Query: 203 XXXXXXXXXEGTDHVLTERDILTTTRSEWLVKLLYAFQDPQSLYLAMEFVPGGDFRTLLL 262
+ +L ER+IL + R+ ++V+ Y+F ++LYL ME++ GGD +LL
Sbjct: 785 LKKADMIRKNAVESILAERNILISVRNPFVVRFFYSFTCRENLYLVMEYLNGGDLFSLLR 844
Query: 263 NTKFLQAPHARFYISEMFCAVNALHQLGYTHRDLKPENFLIDSKGHIKLTDFGLASGTVS 322
N L AR YI+E+ A+ LH + HRDLKP+N LI+ GHIKLTDFGL+ V
Sbjct: 845 NLGCLDEDMARIYIAEVVLALEYLHSVNIIHRDLKPDNLLINQDGHIKLTDFGLSK--VG 902
Query: 323 MERIESMKIRLQEVKNLEFPEFRERSMDDRRRMYNKLREEEVRYAHSTVGSPDYMALEVL 382
+ + N F F E D + +++ ++ R H+ VG+PDY+A E+L
Sbjct: 903 LINSTDDLSGESSLGNSGF--FAE---DGSKAQHSQGKDS--RKKHAVVGTPDYLAPEIL 955
Query: 383 EAKNYDFTVDYWSLGCILFESLVGYTPFSGNSTNETYENLRN----WKHVLQRPKCDNGR 438
+ T D+WS+G ILFE LVG PF+ + + +EN+ N W +V +
Sbjct: 956 LGMGHGKTADWWSVGVILFEVLVGIPPFNAETPQQIFENIINRDIPWPNVPEE------- 1008
Query: 439 YAFSDRTWELITRLIAD-PINRL--KSFEHVKRMRYFSEIDFNTLRTIHPPFIPQLDNEE 495
S +LI +L+ + P+ RL VK+ +F +I+++TL F+P + +
Sbjct: 1009 --ISYEAHDLINKLLTENPVQRLGATGAGEVKQHHFFKDINWDTLARQKAMFVPSAE-PQ 1065
Query: 496 DVGYFDDFTNEEHMARYV 513
D YF M+RY+
Sbjct: 1066 DTSYF--------MSRYI 1075
>At1g45160 [TR] KOG0606 Microtubule-associated serine/threonine kinase and
related proteins
Length = 1067
Score = 167 bits (423), Expect = 4e-41
Identities = 113/334 (33%), Positives = 160/334 (47%), Gaps = 23/334 (6%)
Query: 171 DFEMITXXXXXXXXXXXLARKKDTKEICAXXXXXXXXXXXXEGTDHVLTERDILTTTRSE 230
DFE+I LARK+ T + A + +L ER+IL T R
Sbjct: 669 DFEIIKPISRGAFGKVFLARKRTTGDFFAIKVLKKLDMIRKNDIERILQERNILITVRYP 728
Query: 231 WLVKLLYAFQDPQSLYLAMEFVPGGDFRTLLLNTKFLQAPHARFYISEMFCAVNALHQLG 290
+LV+ Y+F +LYL ME++ GGD +LL L AR YI+E+ A+ LH L
Sbjct: 729 FLVRFFYSFTCRDNLYLVMEYLNGGDLYSLLQKVGCLDEEIARIYIAELVLALEYLHSLK 788
Query: 291 YTHRDLKPENFLIDSKGHIKLTDFGLASGTVSMERIESMKIRLQEVKNLEFPEFRERSMD 350
HRDLKP+N LI GHIKLTDFGL+ KI L + N E +
Sbjct: 789 IVHRDLKPDNLLIAYNGHIKLTDFGLS------------KIGL--INNTIDLSGHESDVS 834
Query: 351 DRRRMYN-KLREEEVRYAHSTVGSPDYMALEVLEAKNYDFTVDYWSLGCILFESLVGYTP 409
R ++ + +EE R HS VG+PDY+A E+L + + D+WS G +LFE L G P
Sbjct: 835 PRTNSHHFQKNQEEERIRHSAVGTPDYLAPEILLGTEHGYAADWWSAGIVLFELLTGIPP 894
Query: 410 FSGNSTNETYENLRNWKHVLQRPKCDNGRYAFSDRTWELITRLIA-DPINRL--KSFEHV 466
F+ + + ++N+ N K + P S +LI RL+ +P RL V
Sbjct: 895 FTASRPEKIFDNILNGK--MPWPDVPG---EMSYEAQDLINRLLVHEPEKRLGANGAAEV 949
Query: 467 KRMRYFSEIDFNTLRTIHPPFIPQLDNEEDVGYF 500
K +F +D+ L F+PQ ++ D YF
Sbjct: 950 KSHPFFQGVDWENLALQKAAFVPQPESINDTSYF 983
>Hs20543401 [TR] KOG0606 Microtubule-associated serine/threonine kinase and
related proteins
Length = 2092
Score = 167 bits (422), Expect = 5e-41
Identities = 116/360 (32%), Positives = 169/360 (46%), Gaps = 43/360 (11%)
Query: 157 TNILRKRRLKPKHKDFEMITXXXXXXXXXXXLARKKDTKEICAXXXXXXXXXXXXEGTDH 216
+N K R KP+ DFE I R K++++ A
Sbjct: 24 SNASLKLRRKPRESDFETIKLISNGAYGAVYFVRHKESRQRFAMKKINKQNLILRNQIQQ 83
Query: 217 VLTERDILTTTRSEWLVKLLYAFQDPQSLYLAMEFVPGGDFRTLLLNTKFLQAPHARFYI 276
ERDILT + ++V + +F+ + L + ME+V GGD TL+ N L AR Y
Sbjct: 84 AFVERDILTFAENPFVVSMYCSFETRRHLCMVMEYVEGGDCATLMKNMGPLPVDMARMYF 143
Query: 277 SEMFCAVNALHQLGYTHRDLKPENFLIDSKGHIKLTDFGLAS-GTVSMERIESMKIRLQE 335
+E A+ LH G HRDLKP+N L+ S GHIKLTDFGL+ G +SM
Sbjct: 144 AETVLALEYLHNYGIVHRDLKPDNLLVTSMGHIKLTDFGLSKVGLMSM------------ 191
Query: 336 VKNLEFPEFRERSMDDRRRMYNKLREEEVRYAHSTVGSPDYMALEVLEAKNYDFTVDYWS 395
NL + D R +K G+P+Y+A EV+ + Y VD+W+
Sbjct: 192 TTNL----YEGHIEKDAREFLDK----------QVCGTPEYIAPEVILRQGYGKPVDWWA 237
Query: 396 LGCILFESLVGYTPFSGNSTNETYENL----RNWKHVLQRPKCDNGRYAFSDRTWELITR 451
+G IL+E LVG PF G++ E + + NW + P D +LIT
Sbjct: 238 MGIILYEFLVGCVPFFGDTPEELFGQVISDEINWPEKDEAPPPD---------AQDLITL 288
Query: 452 LI-ADPINRLKS--FEHVKRMRYFSEIDFNTLRTIHPPFIPQLDNEEDVGYFDDFTNEEH 508
L+ +P+ RL + VK+ R+F +D+N+L FIPQL++E+D YFD + + H
Sbjct: 289 LLRQNPLERLGTGGAYEVKQHRFFRSLDWNSLLRQKAEFIPQLESEDDTSYFDTRSEKYH 348
>Hs4885583 [T] KOG0612 Rho-associated coiled-coil containing protein kinase
Length = 1354
Score = 164 bits (415), Expect = 3e-40
Identities = 111/365 (30%), Positives = 171/365 (46%), Gaps = 53/365 (14%)
Query: 152 YLTKETNILRK-RRLKPKHKDFEMITXXXXXXXXXXXLARKKDTKEICAXXXXXXXXXXX 210
+L++ + + K R L+ K +D+E++ L R K T+++ A
Sbjct: 55 FLSRYKDTINKIRDLRMKAEDYEVVKVIGRGAFGEVQLVRHKSTRKVYAMKLLSKFEMIK 114
Query: 211 XEGTDHVLTERDILTTTRSEWLVKLLYAFQDPQSLYLAMEFVPGGDFRTLLLNTKFLQAP 270
+ ERDI+ S W+V+L YAFQD + LY+ ME++PGGD L+ N +
Sbjct: 115 RSDSAFFWEERDIMAFANSPWVVQLFYAFQDDRYLYMVMEYMPGGDLVNLMSNYD-VPEK 173
Query: 271 HARFYISEMFCAVNALHQLGYTHRDLKPENFLIDSKGHIKLTDFGLASGTVSMERIESMK 330
ARFY +E+ A++A+H +G+ HRD+KP+N L+D GH+KL DFG
Sbjct: 174 WARFYTAEVVLALDAIHSMGFIHRDVKPDNMLLDKSGHLKLADFGTCM------------ 221
Query: 331 IRLQEVKNLEFPEFRERSMDDRRRMYNKLREEEVRYAHSTVGSPDYMALEVLEAKN---- 386
K+ +E + + VG+PDY++ EVL+++
Sbjct: 222 ---------------------------KMNKEGMVRCDTAVGTPDYISPEVLKSQGGDGY 254
Query: 387 YDFTVDYWSLGCILFESLVGYTPFSGNSTNETYENLRNWKHVLQRPKCDNGRYAFSDRTW 446
Y D+WS+G L+E LVG TPF +S TY + N K+ L P DN S
Sbjct: 255 YGRECDWWSVGVFLYEMLVGDTPFYADSLVGTYSKIMNHKNSLTFPD-DND---ISKEAK 310
Query: 447 ELITRLIADPINRL--KSFEHVKRMRYF--SEIDFNTLRTIHPPFIPQLDNEEDVGYFDD 502
LI + D RL E +KR +F + + TLR P +P L ++ D FDD
Sbjct: 311 NLICAFLTDREVRLGRNGVEEIKRHLFFKNDQWAWETLRDTVAPVVPDLSSDIDTSNFDD 370
Query: 503 FTNEE 507
++
Sbjct: 371 LEEDK 375
>Hs4505831 [T] KOG0612 Rho-associated coiled-coil containing protein kinase
Length = 496
Score = 162 bits (410), Expect = 1e-39
Identities = 113/364 (31%), Positives = 164/364 (45%), Gaps = 59/364 (16%)
Query: 148 EWQGYLTKETNILRKRRLKPKHKDFEMITXXXXXXXXXXXLARKKDTKEICAXXXXXXXX 207
EW T + +R R +DFE++ + + K+ ++ A
Sbjct: 58 EWAKPFTSKVKQMRLHR-----EDFEILKVIGRGAFGEVAVVKLKNADKVFAMKILNKWE 112
Query: 208 XXXXEGTDHVLTERDILTTTRSEWLVKLLYAFQDPQSLYLAMEFVPGGDFRTLLLNTKF- 266
T ERD+L ++W+ L YAFQD +LYL M++ GGD TLL +KF
Sbjct: 113 MLKRAETACFREERDVLVNGDNKWITTLHYAFQDDNNLYLVMDYYVGGDLLTLL--SKFE 170
Query: 267 --LQAPHARFYISEMFCAVNALHQLGYTHRDLKPENFLIDSKGHIKLTDFGLASGTVSME 324
L ARFY++EM A++++HQL Y HRD+KP+N L+D GHI+L DFG
Sbjct: 171 DRLPEDMARFYLAEMVIAIDSVHQLHYVHRDIKPDNILMDMNGHIRLADFGSCL------ 224
Query: 325 RIESMKIRLQEVKNLEFPEFRERSMDDRRRMYNKLREEEVRYAHSTVGSPDYMALEVLEA 384
KL E+ + VG+PDY++ E+L+A
Sbjct: 225 ---------------------------------KLMEDGTVQSSVAVGTPDYISPEILQA 251
Query: 385 K-----NYDFTVDYWSLGCILFESLVGYTPFSGNSTNETYENLRNWKHVLQRPKCDNGRY 439
Y D+WSLG ++E L G TPF S ETY + N K Q P
Sbjct: 252 MEDGKGRYGPECDWWSLGVCMYEMLYGETPFYAESLVETYGKIMNHKERFQFPAQVTD-- 309
Query: 440 AFSDRTWELITRLIADPINRL--KSFEHVKRMRYFSEIDFNTLRTIHPPFIPQLDNEEDV 497
S+ +LI RLI +RL E K+ +FS ID++ +R P+IP++ + D
Sbjct: 310 -VSENAKDLIRRLICSREHRLGQNGIEDFKKHPFFSGIDWDNIRNCEAPYIPEVSSPTDT 368
Query: 498 GYFD 501
FD
Sbjct: 369 SNFD 372
>Hs17455844 [TR] KOG0606 Microtubule-associated serine/threonine kinase and
related proteins
Length = 1139
Score = 161 bits (408), Expect = 2e-39
Identities = 113/346 (32%), Positives = 162/346 (46%), Gaps = 33/346 (9%)
Query: 159 ILRKRRLKPKHKDFEMITXXXXXXXXXXXLARKKDTKEICAXXXXXXXXXXXXEGTDHVL 218
++ + R KP DFE I L R +DT++ A V
Sbjct: 184 LVGQSRRKPCESDFETIKLISNGAYGAVYLVRHRDTRQRFAIKKINKQNLILRNQIQQVF 243
Query: 219 TERDILTTTRSEWLVKLLYAFQDPQSLYLAMEFVPGGDFRTLLLNTKFLQAPHARFYISE 278
ERDILT + ++V + +F+ + L + ME+V GGD TLL N L AR Y +E
Sbjct: 244 VERDILTFAENPFVVSMFCSFETRRHLCMVMEYVEGGDCATLLKNMGPLPVDMARLYFAE 303
Query: 279 MFCAVNALHQLGYTHRDLKPENFLIDSKGHIKLTDFGLASGTVSMERIESMKIRLQEVKN 338
A+ LH G HRDLKP+N LI S GHIKLTDFGL+ KI L +
Sbjct: 304 TVLALEYLHNYGIVHRDLKPDNLLITSLGHIKLTDFGLS------------KIGLMSMAT 351
Query: 339 LEFPEFRERSMDDRRRMYNKLREEEVRYAHSTVGSPDYMALEVLEAKNYDFTVDYWSLGC 398
+ E+ D R +K G+P+Y+A EV+ + Y VD+W++G
Sbjct: 352 NLYEGHIEK---DAREFIDK----------QVCGTPEYIAPEVIFRQGYGKPVDWWAMGV 398
Query: 399 ILFESLVGYTPFSGNSTNETYENLRNWKHVLQRPKCDNGRYAFSDRTWELITRLI-ADPI 457
+L+E LVG PF G++ E + + V G A +LITRL+ P+
Sbjct: 399 VLYEFLVGCVPFFGDTPEELFGQV-----VSDEIMWPEGDEALPADAQDLITRLLRQSPL 453
Query: 458 NRLKS--FEHVKRMRYFSEIDFNTLRTIHPPFIPQLDNEEDVGYFD 501
+RL + VK+ +F +D+ L F+PQL+ E+D YFD
Sbjct: 454 DRLGTGGTHEVKQHPFFLALDWAGLLRHKAEFVPQLEAEDDTSYFD 499
>Hs14149671 [TR] KOG0606 Microtubule-associated serine/threonine kinase and
related proteins
Length = 1734
Score = 159 bits (403), Expect = 8e-39
Identities = 116/401 (28%), Positives = 179/401 (43%), Gaps = 38/401 (9%)
Query: 111 CDMFDYVISRRERTRQVINYLEEQRRSNLMGTEQITNEWQGYLTKETNILRKRRLKPKHK 170
CD+ Y++S+ TR + + + + T + + +G+ + + P +
Sbjct: 456 CDIPRYIVSQLGLTRDPLEEMAQLSSCDSPDTPETDDSIEGHGASLPS-----KKTPSEE 510
Query: 171 DFEMITXXXXXXXXXXXLARKKDTKEICAXXXXXXXXXXXXEGTDHVLTERDILTTTRSE 230
DFE I L R K T++ A ERDILT +
Sbjct: 511 DFETIKLISNGAYGAVFLVRHKSTRQRFAMKKINKQNLILRNQIQQAFVERDILTFAENP 570
Query: 231 WLVKLLYAFQDPQSLYLAMEFVPGGDFRTLLLNTKFLQAPHARFYISEMFCAVNALHQLG 290
++V + +F + L + ME+V GGD TLL N L R Y +E A+ LH G
Sbjct: 571 FVVSMFCSFDTKRHLCMVMEYVEGGDCATLLKNIGALPVDMVRLYFAETVLALEYLHNYG 630
Query: 291 YTHRDLKPENFLIDSKGHIKLTDFGLASGTVSMERIESMKIRLQEVKNLEFPEFRERSMD 350
HRDLKP+N LI S GHIKLTDFGL+ K+ L + + E+
Sbjct: 631 IVHRDLKPDNLLITSMGHIKLTDFGLS------------KMGLMSLTTNLYEGHIEK--- 675
Query: 351 DRRRMYNKLREEEVRYAHSTVGSPDYMALEVLEAKNYDFTVDYWSLGCILFESLVGYTPF 410
D R +K G+P+Y+A EV+ + Y VD+W++G IL+E LVG PF
Sbjct: 676 DAREFLDK----------QVCGTPEYIAPEVILRQGYGKPVDWWAMGIILYEFLVGCVPF 725
Query: 411 SGNSTNETYENLRNWKHVLQRPKCDNGRYAFSDRTWELITRLI-ADPINRL--KSFEHVK 467
G++ E + + + G A +L ++L+ +P+ RL S VK
Sbjct: 726 FGDTPEELFGQV-----ISDEIVWPEGDEALPPDAQDLTSKLLHQNPLERLGTGSAYEVK 780
Query: 468 RMRYFSEIDFNTLRTIHPPFIPQLDNEEDVGYFDDFTNEEH 508
+ +F+ +D+ L FIPQL++E+D YFD + H
Sbjct: 781 QHPFFTGLDWTGLLRQKAEFIPQLESEDDTSYFDTRSERYH 821
>CE08098 [T] KOG0612 Rho-associated coiled-coil containing protein kinase
Length = 1173
Score = 159 bits (403), Expect = 8e-39
Identities = 117/414 (28%), Positives = 182/414 (43%), Gaps = 70/414 (16%)
Query: 165 LKPKHKDFEMITXXXXXXXXXXXLARKKDTKEICAXXXXXXXXXXXXEGTDHVLTERDIL 224
L+ K DF + L R T + A + ERDI+
Sbjct: 61 LRMKAADFRQLKVIGRGAFGEVHLVRHTRTNTVYAMKMLNKDDMIKRADSAFFWEERDIM 120
Query: 225 TTTRSEWLVKLLYAFQDPQSLYLAMEFVPGGDFRTLLLNTKFLQAPHARFYISEMFCAVN 284
SEW+V+L YAFQDP+ LY+ ME++PGGD L+ + + + RFY +E+ A+
Sbjct: 121 AHANSEWIVRLQYAFQDPRHLYMVMEYMPGGDLVNLMTSYE-VSEKWTRFYTAEIVEALA 179
Query: 285 ALHQLGYTHRDLKPENFLIDSKGHIKLTDFGLASGTVSMERIESMKIRLQEVKNLEFPEF 344
ALH +GY HRD+KP+N LI GHIKL DFG
Sbjct: 180 ALHSMGYIHRDVKPDNMLISISGHIKLADFGTCV-------------------------- 213
Query: 345 RERSMDDRRRMYNKLREEEVRYAHSTVGSPDYMALEVLEAKNYDF----TVDYWSLGCIL 400
K+ V + VG+PDY++ EVL + D VD+WS+G +
Sbjct: 214 -------------KMNANGVVRCSTAVGTPDYISPEVLRNQGQDAEFGKEVDWWSVGVFI 260
Query: 401 FESLVGYTPFSGNSTNETYENLRNWKHVLQRPKCDNGRYAFSDRTWELITRLIADPINRL 460
+E LVG TPF + TY N+ N K L+ P S + ++I + ++ +RL
Sbjct: 261 YEMLVGETPFYAEALVSTYTNIMNHKTSLKFP----DEPLISTQAKDIIKKFLSAAPDRL 316
Query: 461 --KSFEHVKRMRYF--SEIDFNTLRTIHPPFIPQLDNEEDVGYFDDFTNEEHMARYVDVF 516
S + ++ ++F E F TLR PP IP L +++D +F++ ++
Sbjct: 317 GRNSVDDIRNHKFFVNDEWTFATLREASPPVIPSLKSDDDTTHFEE----------IETR 366
Query: 517 KRQDRLTAMVDDSLSDSKL--VGFTFRHRNG------KDGSSGVLYGGLEQSDP 562
R + + + + ++L +GFT+ + K +G G+EQ P
Sbjct: 367 DRDNAGDFQLPKTFNGNQLPFIGFTYSNEYSPVKNLLKGHGAGSKQNGIEQHKP 420
>7294265 [TR] KOG0606 Microtubule-associated serine/threonine kinase and
related proteins
Length = 2139
Score = 159 bits (402), Expect = 1e-38
Identities = 108/339 (31%), Positives = 166/339 (48%), Gaps = 33/339 (9%)
Query: 167 PKHKDFEMITXXXXXXXXXXXLARKKDTKEICAXXXXXXXXXXXXEGTDHVLTERDILTT 226
P+ DF+++ L + K T++ A + V ERDIL+
Sbjct: 830 PQENDFDIVKLISNGAYGAVYLVKHKTTRQRFAMKKINKNNLILRNQVEQVFAERDILSF 889
Query: 227 TRSEWLVKLLYAFQDPQSLYLAMEFVPGGDFRTLLLNTKFLQAPHARFYISEMFCAVNAL 286
+ ++V + +F+ + L L ME+V GGD TLL N L A ARFY +E AV L
Sbjct: 890 ADNPFVVSMYCSFETKKHLCLVMEYVEGGDCGTLLKNIGPLPADMARFYFAETVLAVEYL 949
Query: 287 HQLGYTHRDLKPENFLIDSKGHIKLTDFGLASGTVSMERIESMKIRLQEVKNLEFPEFRE 346
H G HRDLKP+N LI + GHIKLTDFGL S + S+ L E + +
Sbjct: 950 HSYGIVHRDLKPDNLLITALGHIKLTDFGL-----SKMGLMSLATNLYE----GYIDSET 1000
Query: 347 RSMDDRRRMYNKLREEEVRYAHSTVGSPDYMALEVLEAKNYDFTVDYWSLGCILFESLVG 406
R D++ G+P+Y+A EV+ + Y VD+WS+G IL+E L+G
Sbjct: 1001 RQFSDKQ----------------VYGTPEYIAPEVILRQGYGKPVDWWSMGIILYEFLIG 1044
Query: 407 YTPFSGNSTNETYENLRNWKHVLQRPKCDNGRYAFSDRTWELITRLI-ADPINRLKSFE- 464
PF G +T E + + N ++ P D+ + ++I++L+ +P +RL +
Sbjct: 1045 CVPFFGETTEELFAHTVN--DDIEWP--DSEDWPVQAEAKDIISQLLQQNPRDRLGTQSG 1100
Query: 465 --HVKRMRYFSEIDFNTLRTIHPPFIPQLDNEEDVGYFD 501
+K YF +D+N+L F+PQL +++D YFD
Sbjct: 1101 ALEMKEHEYFLGMDWNSLLRQKAEFVPQLSHDDDTSYFD 1139
>CE11916 [T] KOG0612 Rho-associated coiled-coil containing protein kinase
Length = 1548
Score = 157 bits (398), Expect = 3e-38
Identities = 108/361 (29%), Positives = 166/361 (45%), Gaps = 62/361 (17%)
Query: 156 ETNILRKRRLKPKHKDFEMITXXXXXXXXXXXLARKKDTKEICAXXXXXXXXXXXXEGTD 215
+T I + ++L+ DFE++ + R + EI A T
Sbjct: 67 KTVISKAKKLRLSRDDFEVLKVIGKGAFGEVAVVRMRGVGEIYAMKILNKWEMVKRAETA 126
Query: 216 HVLTERDILTTTRSEWLVKLLYAFQDPQSLYLAMEFVPGGDFRTLLLNTKFLQ---APHA 272
ERD+L W+ L YAFQD ++LY M++ GGD TLL +KF+ A
Sbjct: 127 CFREERDVLVYGDRRWITNLHYAFQDEKNLYFVMDYYIGGDMLTLL--SKFVDHIPESMA 184
Query: 273 RFYISEMFCAVNALHQLGYTHRDLKPENFLIDSKGHIKLTDFG-----LASGTVSMERIE 327
+FYI+EM A+++LH+LGY HRD+KP+N L+D +GHI+L DFG LA G+V+
Sbjct: 185 KFYIAEMVLAIDSLHRLGYVHRDVKPDNVLLDMQGHIRLADFGSCLRILADGSVA----- 239
Query: 328 SMKIRLQEVKNLEFPEFRERSMDDRRRMYNKLREEEVRYAHSTVGSPDYMALEVLEAK-- 385
++ VG+PDY++ E+L A
Sbjct: 240 ---------------------------------------SNVAVGTPDYISPEILRAMED 260
Query: 386 ---NYDFTVDYWSLGCILFESLVGYTPFSGNSTNETYENLRNWKHVLQRPKCDNGRYAFS 442
Y D+WSLG ++E L G TPF +TY + + + +L P D + S
Sbjct: 261 GRGRYGKECDWWSLGICMYEMLYGTTPFYSERLVDTYGKIMSHQDMLDFPD-DEIDWVVS 319
Query: 443 DRTWELITRLIADPINRL--KSFEHVKRMRYFSEIDFNTLRTIHPPFIPQLDNEEDVGYF 500
+ +LI +LI R + +F ID+NT+R +PP++P++ + ED F
Sbjct: 320 EEAKDLIRQLICSSDVRFGRNGLSDFQLHPFFEGIDWNTIRDSNPPYVPEVSSPEDTSNF 379
Query: 501 D 501
D
Sbjct: 380 D 380
>7291742_1 [T] KOG0612 Rho-associated coiled-coil containing protein kinase
Length = 1539
Score = 157 bits (397), Expect = 4e-38
Identities = 109/390 (27%), Positives = 174/390 (43%), Gaps = 62/390 (15%)
Query: 163 RRLKPKHKDFEMITXXXXXXXXXXXLARKKDTKEICAXXXXXXXXXXXXEGTDHVLTERD 222
R+L+ DF+++ + + T+++ A T ERD
Sbjct: 91 RKLRLSRDDFDILKIIGRGAFGEVCVVQMISTEKVYAMKILNKWEMLKRAETACFREERD 150
Query: 223 ILTTTRSEWLVKLLYAFQDPQSLYLAMEFVPGGDFRTLLLNTKF---LQAPHARFYISEM 279
+L +W+ L YAFQD +LYL M++ GGD TLL +KF L A+FYI+EM
Sbjct: 151 VLVFGDRQWITNLHYAFQDNINLYLVMDYYCGGDLLTLL--SKFEDKLPEDMAKFYITEM 208
Query: 280 FCAVNALHQLGYTHRDLKPENFLIDSKGHIKLTDFGLASGTVSMERIESMKIRLQEVKNL 339
A+N++HQ+ Y HRD+KP+N L+D +GH++L DFG
Sbjct: 209 ILAINSIHQIRYVHRDIKPDNVLLDKRGHVRLADFGSCL--------------------- 247
Query: 340 EFPEFRERSMDDRRRMYNKLREEEVRYAHSTVGSPDYMALEVLEAK-----NYDFTVDYW 394
+L ++ ++ VG+PDY++ E+L A Y D+W
Sbjct: 248 ------------------RLDKDGTVQSNVAVGTPDYISPEILRAMEDGKGRYGTECDWW 289
Query: 395 SLGCILFESLVGYTPFSGNSTNETYENLRNWKHVLQRPKCDNGRYAFSDRTWELITRLIA 454
SLG ++E L G TPF S ETY + N ++ P + Y S+ + +L+ +LI
Sbjct: 290 SLGVCMYEMLYGETPFYAESLVETYGKIMNHQNCFNLPSQETLNYKVSETSQDLLCKLIC 349
Query: 455 DPINRL--KSFEHVKRMRYFSEIDFNTLRTIHPPFIPQLDNEEDVGYFDDFTNEEHMARY 512
P NRL + +F ID+ +R P++P++ + D FD N+ +
Sbjct: 350 IPENRLGQNGIQDFMDHPWFVGIDWKNIRQGPAPYVPEVSSPTDTSNFDVDDNDVRLT-- 407
Query: 513 VDVFKRQDRLTAMVDDSLSDSKL--VGFTF 540
D + + + S L +GFTF
Sbjct: 408 -------DSIPPSANPAFSGFHLPFIGFTF 430
>Hs16357474_1 [T] KOG0612 Rho-associated coiled-coil containing protein kinase
Length = 1530
Score = 156 bits (395), Expect = 7e-38
Identities = 106/349 (30%), Positives = 155/349 (44%), Gaps = 54/349 (15%)
Query: 163 RRLKPKHKDFEMITXXXXXXXXXXXLARKKDTKEICAXXXXXXXXXXXXEGTDHVLTERD 222
+ ++ +DFE+I + + K+T+ I A T ERD
Sbjct: 67 KEMQLHREDFEIIKVIGRGAFGEVAVVKMKNTERIYAMKILNKWEMLKRAETACFREERD 126
Query: 223 ILTTTRSEWLVKLLYAFQDPQSLYLAMEFVPGGDFRTLLLNTKF---LQAPHARFYISEM 279
+L +W+ L YAFQD LYL M++ GGD TLL +KF L ARFYI EM
Sbjct: 127 VLVNGDCQWITALHYAFQDENHLYLVMDYYVGGDLLTLL--SKFEDKLPEDMARFYIGEM 184
Query: 280 FCAVNALHQLGYTHRDLKPENFLIDSKGHIKLTDFGLASGTVSMERIESMKIRLQEVKNL 339
A++++HQL Y HRD+KP+N L+D GHI+L DFG
Sbjct: 185 VLAIDSIHQLHYVHRDIKPDNVLLDVNGHIRLADFGSCL--------------------- 223
Query: 340 EFPEFRERSMDDRRRMYNKLREEEVRYAHSTVGSPDYMALEVLEAK-----NYDFTVDYW 394
K+ ++ + VG+PDY++ E+L+A Y D+W
Sbjct: 224 ------------------KMNDDGTVQSSVAVGTPDYISPEILQAMEDGMGKYGPECDWW 265
Query: 395 SLGCILFESLVGYTPFSGNSTNETYENLRNWKHVLQRPKCDNGRYAFSDRTWELITRLIA 454
SLG ++E L G TPF S ETY + N + Q P S+ +LI RLI
Sbjct: 266 SLGVCMYEMLYGETPFYAESLVETYGKIMNHEERFQFPSHVTD---VSEEAKDLIQRLIC 322
Query: 455 DPINRL--KSFEHVKRMRYFSEIDFNTLRTIHPPFIPQLDNEEDVGYFD 501
RL E K+ +F +++ +R + P+IP + + D FD
Sbjct: 323 SRERRLGQNGIEDFKKHAFFEGLNWENIRNLEAPYIPDVSSPSDTSNFD 371
>Hs4759050 [T] KOG0603 Ribosomal protein S6 kinase
Length = 740
Score = 156 bits (394), Expect = 9e-38
Identities = 116/379 (30%), Positives = 166/379 (43%), Gaps = 63/379 (16%)
Query: 140 MGTEQITNEWQGYLTKE---TNILRKRRLKPKHKDFEMITXXXXXXXXXXXLARKKDTKE 196
MG E+I + + KE T+ +++ K FE++ L +K +
Sbjct: 33 MGEEEINPQTEEVSIKEIAITHHVKEGHEKADPSQFELLKVLGQGSFGKVFLVKKISGSD 92
Query: 197 ICAXXXXXXXXXXXXEGTDHVLT--ERDILTTTRSEWLVKLLYAFQDPQSLYLAMEFVPG 254
+ D V T ERDIL ++VKL YAFQ LYL ++F+ G
Sbjct: 93 ARQLYAMKVLKKATLKVRDRVRTKMERDILVEVNHPFIVKLHYAFQTEGKLYLILDFLRG 152
Query: 255 GDFRTLLLNTKFLQAPHARFYISEMFCAVNALHQLGYTHRDLKPENFLIDSKGHIKLTDF 314
GD T L +FY++E+ A++ LH LG +RDLKPEN L+D +GHIKLTDF
Sbjct: 153 GDLFTRLSKEVMFTEEDVKFYLAELALALDHLHSLGIIYRDLKPENILLDEEGHIKLTDF 212
Query: 315 GLASGTVSMERIESMKIRLQEVKNLEFPEFRERSMDDRRRMYNKLREEEVRYAHSTVGSP 374
GL+ ++ E + A+S G+
Sbjct: 213 GLSKESIDHE----------------------------------------KKAYSFCGTV 232
Query: 375 DYMALEVLEAKNYDFTVDYWSLGCILFESLVGYTPFSGNSTNETYENLRNWKHVLQRPKC 434
+YMA EV+ + + + D+WS G ++FE L G PF G ET + K
Sbjct: 233 EYMAPEVVNRRGHTQSADWWSFGVLMFEMLTGTLPFQGKDRKETMTMIL---------KA 283
Query: 435 DNGRYAFSDRTWELITRLI--ADPINRL----KSFEHVKRMRYFSEIDFNTL--RTIHPP 486
G F + + R++ +P NRL E +KR +FS ID+N L R IHPP
Sbjct: 284 KLGMPQFLSPEAQSLLRMLFKRNPANRLGAGPDGVEEIKRHSFFSTIDWNKLYRREIHPP 343
Query: 487 FIPQLDNEEDVGYFD-DFT 504
F P ED YFD +FT
Sbjct: 344 FKPATGRPEDTFYFDPEFT 362
Score = 73.2 bits (178), Expect = 1e-12
Identities = 58/242 (23%), Positives = 101/242 (40%), Gaps = 53/242 (21%)
Query: 232 LVKLLYAFQDPQSLYLAMEFVPGGDFRTLLLNTKFLQAPHARFYISEMFCAVNALHQLGY 291
++ L + D + +Y+ E + GG+ +L KF A + + V LH G
Sbjct: 476 IITLKDVYDDGKYVYVVTELMKGGELLDKILRQKFFSEREASAVLFTITKTVEYLHAQGV 535
Query: 292 THRDLKPENFL-IDSKGH---IKLTDFGLASGTVSMERIESMKIRLQEVKNLEFPEFRER 347
HRDLKP N L +D G+ I++ DFG A
Sbjct: 536 VHRDLKPSNILYVDESGNPESIRICDFGFA------------------------------ 565
Query: 348 SMDDRRRMYNKLREEEVRYAHSTVGSPDYMALEVLEAKNYDFTVDYWSLGCILFESLVGY 407
+LR E + + +++A EVL+ + YD D WSLG +L+ L GY
Sbjct: 566 ---------KQLRAEN-GLLMTPCYTANFVAPEVLKRQGYDAACDIWSLGVLLYTMLTGY 615
Query: 408 TPFSGNSTNETYENLRNWKHVLQRPKCDNGRYAFSDRTWELITRLIADPINRLKSFEHVK 467
TPF+ N ++T E + + +G+++ S W ++ D ++++ + +
Sbjct: 616 TPFA-NGPDDTPEEI--------LARIGSGKFSLSGGYWNSVSDTAKDLVSKMLHVDPHQ 666
Query: 468 RM 469
R+
Sbjct: 667 RL 668
>YNR047w [R] KOG0610 Putative serine/threonine protein kinase
Length = 893
Score = 155 bits (392), Expect = 2e-37
Identities = 108/369 (29%), Positives = 175/369 (47%), Gaps = 36/369 (9%)
Query: 128 INYLEEQRRSNLMGTEQITNEWQGYLTKETNILRKRRLKPKHKDFEMITXXXXXXXXXXX 187
I+ E RRS + T+ +N++Q + + FE I
Sbjct: 465 ISDFPEPRRSRRLRTKSFSNKFQDIMVGP-------------QSFEKIRLLGQGDVGKVF 511
Query: 188 LARKKDTKEICAXXXXXXXXXXXXEGTDHVLTERDILTTTRSEWLVKLLYAFQDPQSLYL 247
L R+K T + A VLTE++IL T+ ++V L ++FQ LYL
Sbjct: 512 LVREKKTNRVYALKVLSKDEMIKRNKIKRVLTEQEILATSNHPFIVTLYHSFQSEDYLYL 571
Query: 248 AMEFVPGGDFRTLLLN--TKFLQAPHARFYISEMFCAVNALHQLGYTHRDLKPENFLIDS 305
ME+ GG+F L TK + ARFY SE+ A+ LH LG+ +RDLKPEN L+
Sbjct: 572 CMEYCMGGEFFRALQTRKTKCICEDDARFYASEVTAALEYLHLLGFIYRDLKPENILLHQ 631
Query: 306 KGHIKLTDFGLASGTVSMERIESMKIRLQEVKNLEFPEFRERSMDDRRRMYNKLREEEVR 365
GHI L+DF L+ I++ ++ VK + ++ D + + R
Sbjct: 632 SGHIMLSDFDLS--------IQAKDSKVPVVKGSA-----QSTLVDTKICSDGFR----- 673
Query: 366 YAHSTVGSPDYMALEVLEAKNYDFTVDYWSLGCILFESLVGYTPFSGNSTNETYENLRNW 425
+S VG+ +Y+A EV+ + VD+W+LG +++E L G+TPF G++TNET+ N+
Sbjct: 674 -TNSFVGTEEYIAPEVIRGNGHTAAVDWWTLGILIYEMLFGFTPFKGDNTNETFTNI--L 730
Query: 426 KHVLQRPKCDNGRYAFSDRTWELITRLIADPINRLKSFEHVKRMRYFSEIDFNTLRTIHP 485
K+ + P + D +L+T+ + + VK+ +F ++ ++ LR P
Sbjct: 731 KNEVSFPNNNEISRTCKDLIKKLLTKNESKRLGCKMGAADVKKHPFFKKVQWSLLRNQEP 790
Query: 486 PFIPQLDNE 494
P IP L +
Sbjct: 791 PLIPVLSED 799
>CE20493 [TR] KOG0606 Microtubule-associated serine/threonine kinase and
related proteins
Length = 1370
Score = 154 bits (389), Expect = 3e-37
Identities = 107/343 (31%), Positives = 154/343 (44%), Gaps = 33/343 (9%)
Query: 167 PKHKDFEMITXXXXXXXXXXXLARKKDTKEICAXXXXXXXXXXXXEGTDHVLTERDILTT 226
P DF+ I L R ++T++ A D V ERDILT
Sbjct: 353 PCEDDFDTIRLVSNGAYGAVYLVRHRETRQRFALKKMNKQTLMLRNQVDQVFAERDILTM 412
Query: 227 TRSEWLVKLLYAFQDPQSLYLAMEFVPGGDFRTLLLNTKFLQAPHARFYISEMFCAVNAL 286
+ ++V +F+ Q L + ME+V GGD LL + L R Y++E A+ L
Sbjct: 413 ADNPFVVSFYGSFETRQYLCMLMEYVEGGDCAALLKSAGTLPVELVRLYVAETILAIEYL 472
Query: 287 HQLGYTHRDLKPENFLIDSKGHIKLTDFGLASGTVSMERIESMKIRLQEVKNLEFPEFRE 346
H G HRDLKP+N LI + GHIKLTDFGL+ KI L L
Sbjct: 473 HSYGIVHRDLKPDNLLITAMGHIKLTDFGLS------------KIGLMNRTTLV------ 514
Query: 347 RSMDDRRRMYNKLREEEVRYAHSTVGSPDYMALEVLEAKNYDFTVDYWSLGCILFESLVG 406
Y+ + E + G+P+Y+A EV+ + Y VD+W+LG IL+E LVG
Sbjct: 515 ------AEGYDAVVETQQFQDKQLCGTPEYIAPEVILRRGYGKPVDWWALGIILYEFLVG 568
Query: 407 YTPFSGNSTNETYENLRNWKHVLQRPKCDNGRYAFSDRTWELITRLI----ADPINRLKS 462
PF G + + + + ++ P+ D A +L RL+ A+ + L
Sbjct: 569 IVPFFGETPEALFSKVIS--EDVEYPEEDE---ALPPEAADLCRRLLEKNPAERLGTLNG 623
Query: 463 FEHVKRMRYFSEIDFNTLRTIHPPFIPQLDNEEDVGYFDDFTN 505
+ +F +DF +L F+PQLDNEED YFD T+
Sbjct: 624 AAQLMAHEFFILLDFTSLLRQKAEFVPQLDNEEDTSYFDTRTD 666
>Hs10334852 [T] KOG0612 Rho-associated coiled-coil containing protein kinase
Length = 623
Score = 153 bits (387), Expect = 6e-37
Identities = 105/358 (29%), Positives = 160/358 (44%), Gaps = 56/358 (15%)
Query: 156 ETNILRKRRLKPKHKDFEMITXXXXXXXXXXXLARKKDTKEICAXXXXXXXXXXXXEGTD 215
E ++R + ++ + DFE++ + + K T ++ A
Sbjct: 55 EPIVVRLKEVRLQRDDFEILKVIGRGAFSEVAVVKMKQTGQVYAMKIMNKWDMLKRGEVS 114
Query: 216 HVLTERDILTTTRSEWLVKLLYAFQDPQSLYLAMEFVPGGDFRTLLLNTKF---LQAPHA 272
ERD+L W+ +L +AFQD LYL ME+ GGD TLL +KF + A A
Sbjct: 115 CFREERDVLVNGDRRWITQLHFAFQDENYLYLVMEYYVGGDLLTLL--SKFGERIPAEMA 172
Query: 273 RFYISEMFCAVNALHQLGYTHRDLKPENFLIDSKGHIKLTDFGLASGTVSMERIESMKIR 332
RFY++E+ A++++H+LGY HRD+KP+N L+D GHI+L DFG
Sbjct: 173 RFYLAEIVMAIDSVHRLGYVHRDIKPDNILLDRCGHIRLADFGSCL-------------- 218
Query: 333 LQEVKNLEFPEFRERSMDDRRRMYNKLREEEVRYAHSTVGSPDYMALEVLEA-------K 385
KLR + + VG+PDY++ E+L+A
Sbjct: 219 -------------------------KLRADGTVRSLVAVGTPDYLSPEILQAVGGGPGTG 253
Query: 386 NYDFTVDYWSLGCILFESLVGYTPFSGNSTNETYENLRNWKHVLQRPKCDNGRYAFSDRT 445
+Y D+W+LG +E G TPF +ST ETY + ++K L P D G +
Sbjct: 254 SYGPECDWWALGVFAYEMFYGQTPFYADSTAETYGKIVHYKEHLSLPLVDEG---VPEEA 310
Query: 446 WELITRLIADPINRL--KSFEHVKRMRYFSEIDFNTLRTIHPPFIPQLDNEEDVGYFD 501
+ I RL+ P RL + +F +D++ LR PPF P + D FD
Sbjct: 311 RDFIQRLLCPPETRLGRGGAGDFRTHPFFFGLDWDGLRDSVPPFTPDFEGATDTCNFD 368
>Hs20536595 [T] KOG0612 Rho-associated coiled-coil containing protein kinase
Length = 1388
Score = 151 bits (382), Expect = 2e-36
Identities = 110/402 (27%), Positives = 182/402 (44%), Gaps = 62/402 (15%)
Query: 152 YLTKETNILRK-RRLKPKHKDFEMITXXXXXXXXXXXLARKKDTKEICAXXXXXXXXXXX 210
+L + I++K R L+ K +D++++ L R K ++++ A
Sbjct: 71 FLNRYEKIVKKIRGLQMKAEDYDVVKVIGRGAFGEVQLVRHKASQKVYAMKLLSKFEMIK 130
Query: 211 XEGTDHVLTERDILTTTRSEWLVKLLYAFQDPQSLYLAMEFVPGGDFRTLLLNTKFLQAP 270
+ ERDI+ S W+V+L YAFQD + LY+ ME++PGGD L+ N +
Sbjct: 131 RSDSAFFWEERDIMAFANSPWVVQLFYAFQDDRYLYMVMEYMPGGDLVNLMSNYD-VPEK 189
Query: 271 HARFYISEMFCAVNALHQLGYTHRDLKPENFLIDSKGHIKLTDFGLASGTVSMERIESMK 330
A+FY +E+ A++A+H +G HRD+KP+N L+D GH+KL DFG
Sbjct: 190 WAKFYTAEVVLALDAIHSMGLIHRDVKPDNMLLDKHGHLKLADFGTCM------------ 237
Query: 331 IRLQEVKNLEFPEFRERSMDDRRRMYNKLREEEVRYAHSTVGSPDYMALEVLEAKN---- 386
K+ E + + + VG+PDY++ EVL+++
Sbjct: 238 ---------------------------KMDETGMVHCDTAVGTPDYISPEVLKSQGGDGF 270
Query: 387 YDFTVDYWSLGCILFESLVGYTPFSGNSTNETYENLRNWKHVLQRPKCDNGRYAFSDRTW 446
Y D+WS+G L+E LVG TPF +S TY + + K+ L C S
Sbjct: 271 YGRECDWWSVGVFLYEMLVGDTPFYADSLVGTYSKIMDHKNSL----CFPEDAEISKHAK 326
Query: 447 ELITRLIADPINRL--KSFEHVKRMRYF--SEIDFNTLRTIHPPFIPQLDNEEDVGYFDD 502
LI + D RL E +++ +F + ++ +R P +P+L ++ D FDD
Sbjct: 327 NLICAFLTDREVRLGRNGVEEIRQHPFFKNDQWHWDNIRETAAPVVPELSSDIDSSNFDD 386
Query: 503 FTNEEHMARYVDVFKRQDRLTAMVDDSLSDSKLVGFTFRHRN 544
+++ + K A V + L +GFT+ N
Sbjct: 387 IEDDKGDVETFPIPK------AFVGNQL---PFIGFTYYREN 419
>Hs4759044 [T] KOG0612 Rho-associated coiled-coil containing protein kinase
Length = 1388
Score = 150 bits (379), Expect = 5e-36
Identities = 109/402 (27%), Positives = 182/402 (45%), Gaps = 62/402 (15%)
Query: 152 YLTKETNILRK-RRLKPKHKDFEMITXXXXXXXXXXXLARKKDTKEICAXXXXXXXXXXX 210
+L + I++K + L+ K +D++++ L R K ++++ A
Sbjct: 71 FLNRYEKIVKKIKGLQMKAEDYDVVKVIGRGAFGEVQLVRHKASQKVYAMKLLSKFEMIK 130
Query: 211 XEGTDHVLTERDILTTTRSEWLVKLLYAFQDPQSLYLAMEFVPGGDFRTLLLNTKFLQAP 270
+ ERDI+ S W+V+L YAFQD + LY+ ME++PGGD L+ N +
Sbjct: 131 RSDSAFFWEERDIMAFANSPWVVQLFYAFQDDRYLYMVMEYMPGGDLVNLMSNYD-VPEK 189
Query: 271 HARFYISEMFCAVNALHQLGYTHRDLKPENFLIDSKGHIKLTDFGLASGTVSMERIESMK 330
A+FY +E+ A++A+H +G HRD+KP+N L+D GH+KL DFG
Sbjct: 190 WAKFYTAEVVLALDAIHSMGLIHRDVKPDNMLLDKHGHLKLADFGTCM------------ 237
Query: 331 IRLQEVKNLEFPEFRERSMDDRRRMYNKLREEEVRYAHSTVGSPDYMALEVLEAKN---- 386
K+ E + + + VG+PDY++ EVL+++
Sbjct: 238 ---------------------------KMDETGMVHCDTAVGTPDYISPEVLKSQGGDGF 270
Query: 387 YDFTVDYWSLGCILFESLVGYTPFSGNSTNETYENLRNWKHVLQRPKCDNGRYAFSDRTW 446
Y D+WS+G L+E LVG TPF +S TY + + K+ L C S
Sbjct: 271 YGRECDWWSVGVFLYEMLVGDTPFYADSLVGTYSKIMDHKNSL----CFPEDAEISKHAK 326
Query: 447 ELITRLIADPINRL--KSFEHVKRMRYF--SEIDFNTLRTIHPPFIPQLDNEEDVGYFDD 502
LI + D RL E +++ +F + ++ +R P +P+L ++ D FDD
Sbjct: 327 NLICAFLTDREVRLGRNGVEEIRQHPFFKNDQWHWDNIRETAAPVVPELSSDIDSSNFDD 386
Query: 503 FTNEEHMARYVDVFKRQDRLTAMVDDSLSDSKLVGFTFRHRN 544
+++ + K A V + L +GFT+ N
Sbjct: 387 IEDDKGDVETFPIPK------AFVGNQL---PFIGFTYYREN 419
>YCR091w [R] KOG0610 Putative serine/threonine protein kinase
Length = 720
Score = 149 bits (377), Expect = 8e-36
Identities = 128/503 (25%), Positives = 224/503 (44%), Gaps = 73/503 (14%)
Query: 21 VNFSFDTDAKVM-LDPPSTPTRIRGSPSPTRSIVKNPEN----SLMDIDDDTQ------- 68
++ S DA++ D P+ P+ +PS I K+ N SL DI+++ +
Sbjct: 164 ISGSSSPDAELFTFDMPTDPSSFH-TPSSPSYIAKDSRNLSNGSLNDINENEELQNFHRK 222
Query: 69 ----GDLTADITKSPKKLPKDFYKKSSKTKSKRLVSVCQMYFLDYYCDMF---------- 114
G + S P D +K+S+T+ ++ + F
Sbjct: 223 ISENGSASPLANLSLSNSPIDSPRKNSETRKDQIPMNITPRLRRAASEPFNTAKDGLMRE 282
Query: 115 DYVISRRERTRQVINYLEEQRRSNLMGTEQITNEWQGYLTKETNILRKRRLKPKHKDFEM 174
DY+ ++ + + + E RRS + T+ N++Q + + FE
Sbjct: 283 DYIALKQPPS---LGDIVEPRRSRRLRTKSFGNKFQDITVEP-------------QSFEK 326
Query: 175 ITXXXXXXXXXXXLARKKDTKEICAXXXXXXXXXXXXEGTDHVLTERDILTTTRSEWLVK 234
I L R++DT +I A + VLTE++IL T+ ++V
Sbjct: 327 IRLLGQGDVGKVYLMRERDTNQIFALKVLNKHEMIKRKKIKRVLTEQEILATSDHPFIVT 386
Query: 235 LLYAFQDPQSLYLAMEFVPGGDFRTLLLN--TKFLQAPHARFYISEMFCAVNALHQLGYT 292
L ++FQ LYL ME+ GG+F L +K + A+FY SE+ A+ LH LG+
Sbjct: 387 LYHSFQTKDYLYLCMEYCMGGEFFRALQTRKSKCIAEEDAKFYASEVVAALEYLHLLGFI 446
Query: 293 HRDLKPENFLIDSKGHIKLTDFGLASGTVSMERIESMKIRLQEVKNLEFPEFRERSMDDR 352
+RDLKPEN L+ GH+ L+DF L+ ++ ++ +M D
Sbjct: 447 YRDLKPENILLHQSGHVMLSDFDLS---------------------IQATGSKKPTMKDS 485
Query: 353 RRMYNKLREEEVRYAHSTVGSPDYMALEVLEAKNYDFTVDYWSLGCILFESLVGYTPFSG 412
+ K+ + R +S VG+ +Y+A EV+ + VD+W+LG +++E L G TPF G
Sbjct: 486 TYLDTKICSDGFR-TNSFVGTEEYLAPEVIRGNGHTAAVDWWTLGILIYEMLFGCTPFKG 544
Query: 413 NSTNETYENL--RNWKHVLQRPKCDNGRYAFSDRTWELITRLIADPINRLKSFEHVKRMR 470
+++NET+ N+ ++ K + N + D +L+ + A + +KR
Sbjct: 545 DNSNETFSNILTKDVKFPHDKEVSKNCK----DLIKKLLNKNEAKRLGSKSGAADIKRHP 600
Query: 471 YFSEIDFNTLRTIHPPFIPQLDN 493
+F ++ ++ LR PP IP L++
Sbjct: 601 FFKKVQWSFLRNQDPPLIPALND 623
>Hs7657526 [T] KOG0603 Ribosomal protein S6 kinase
Length = 745
Score = 149 bits (376), Expect = 1e-35
Identities = 108/342 (31%), Positives = 152/342 (43%), Gaps = 58/342 (16%)
Query: 172 FEMITXXXXXXXXXXXLARKKDTKEICAXXXXXXXXXXXXEGTDHVLT--ERDILTTTRS 229
FE++ L RKK + + D V T ERDIL
Sbjct: 73 FELLKVLGQGSFGKVFLVRKKTGPDAGQLYAMKVLKKASLKVRDRVRTKMERDILVEVNH 132
Query: 230 EWLVKLLYAFQDPQSLYLAMEFVPGGDFRTLLLNTKFLQAPHARFYISEMFCAVNALHQL 289
++VKL YAFQ LYL ++F+ GGD T L +FY++E+ A++ LHQL
Sbjct: 133 PFIVKLHYAFQTEGKLYLILDFLRGGDVFTRLSKEVLFTEEDVKFYLAELALALDHLHQL 192
Query: 290 GYTHRDLKPENFLIDSKGHIKLTDFGLASGTVSMERIESMKIRLQEVKNLEFPEFRERSM 349
G +RDLKPEN L+D GHIKLTDFGL+ +V E
Sbjct: 193 GIVYRDLKPENILLDEIGHIKLTDFGLSKESVDQE------------------------- 227
Query: 350 DDRRRMYNKLREEEVRYAHSTVGSPDYMALEVLEAKNYDFTVDYWSLGCILFESLVGYTP 409
+ A+S G+ +YMA EV+ + + + D+WS G ++FE L G P
Sbjct: 228 ---------------KKAYSFCGTVEYMAPEVVNRRGHSQSADWWSYGVLMFEMLTGTLP 272
Query: 410 FSGNSTNETYENLRNWKHVLQRPKCDNGRYAFSDRTWELITRLI--ADPINRLKS--FEH 465
F G NET + K G F + + R++ +P NRL S E
Sbjct: 273 FQGKDRNETMNMIL---------KAKLGMPQFLSAEAQSLLRMLFKRNPANRLGSEGVEE 323
Query: 466 VKRMRYFSEIDFNTL--RTIHPPFIPQLDNEEDVGYFD-DFT 504
+KR +F+ ID++ L R + PPF P +D FD +FT
Sbjct: 324 IKRHLFFANIDWDKLYKREVQPPFKPASGKPDDTFCFDPEFT 365
>SPAC22E12.14c [RT] KOG0598 Ribosomal protein S6 kinase and related proteins
Length = 646
Score = 147 bits (372), Expect = 3e-35
Identities = 114/375 (30%), Positives = 175/375 (46%), Gaps = 61/375 (16%)
Query: 188 LARKKDTKEICAXXXXXXXXXXXXEGTDHVLTERDILTTTR---SEWLVKLLYAFQDPQS 244
L RKKDT+ + A + H + ERDIL T S ++V L ++FQ P+
Sbjct: 282 LVRKKDTERVYAMKVLSKKVIVRRKEVAHTVGERDILVQTSAADSPFIVALRFSFQTPKD 341
Query: 245 LYLAMEFVPGGDFRTLLLNTKFLQAPHARFYISEMFCAVNALHQLGYTHRDLKPENFLID 304
LYL +++ GG+ L + A+FYI+E+ A+ ALH+ G +RDLKPEN L+D
Sbjct: 342 LYLVTDYMAGGELFWHLQKSVRFPEERAKFYIAELLLALQALHKRGIVYRDLKPENILLD 401
Query: 305 SKGHIKLTDFGLASGTVSMERIESMKIRLQEVKNLEFPEFRERSMDDRRRMYNKLREEEV 364
+GHI L DFGL+ +S+
Sbjct: 402 VQGHIALCDFGLSKANLSVGTT-------------------------------------- 423
Query: 365 RYAHSTVGSPDYMALEV-LEAKNYDFTVDYWSLGCILFESLVGYTPFSGNSTNETYENLR 423
+ G+ DY+A EV L+ YD VD+WSLG +L+E G++PF ++T + Y+N+
Sbjct: 424 --TRTFCGTTDYLAPEVILDEAGYDMMVDFWSLGVLLYEMTCGWSPFYADNTQQLYKNI- 480
Query: 424 NWKHVLQRPKCDNGRYAFSDRTWELITRLI-ADPINRLKS---FEHVKRMRYFSEIDFNT 479
V + + G + R +LI L+ +P +RL + E V + +F ID+
Sbjct: 481 ----VFGKVRFPRGLLSVEAR--DLIKLLLNRNPKHRLGAHGDVEEVMKHPFFDGIDWKK 534
Query: 480 L--RTIHPPFIPQLDNEEDVGYFD-DFTNEEHMARYVDVFKRQDRLTAMVDDSLSDSKLV 536
L + I PPF P ++ E DV FD +FTN+ A D + T+ S +
Sbjct: 535 LAAKEISPPFKPIVEGEIDVSNFDVEFTNK---AIDRDFSSTDEMSTSAPLSSTVQNGFK 591
Query: 537 GFTFRHRNGKDGSSG 551
GFT+ + D + G
Sbjct: 592 GFTYIDASAMDEAFG 606
>Hs20149547 [T] KOG0603 Ribosomal protein S6 kinase
Length = 735
Score = 145 bits (367), Expect = 1e-34
Identities = 96/293 (32%), Positives = 139/293 (46%), Gaps = 54/293 (18%)
Query: 220 ERDILTTTRSEWLVKLLYAFQDPQSLYLAMEFVPGGDFRTLLLNTKFLQAPHARFYISEM 279
ERDIL ++VKL YAFQ LYL ++F+ GGD T L +FY++E+
Sbjct: 112 ERDILADVNHPFVVKLHYAFQTEGKLYLILDFLRGGDLFTRLSKEVMFTEEDVKFYLAEL 171
Query: 280 FCAVNALHQLGYTHRDLKPENFLIDSKGHIKLTDFGLASGTVSMERIESMKIRLQEVKNL 339
++ LH LG +RDLKPEN L+D +GHIKLTDFGL+ + E
Sbjct: 172 ALGLDHLHSLGIIYRDLKPENILLDEEGHIKLTDFGLSKEAIDHE--------------- 216
Query: 340 EFPEFRERSMDDRRRMYNKLREEEVRYAHSTVGSPDYMALEVLEAKNYDFTVDYWSLGCI 399
+ A+S G+ +YMA EV+ + + + D+WS G +
Sbjct: 217 -------------------------KKAYSFCGTVEYMAPEVVNRQGHSHSADWWSYGVL 251
Query: 400 LFESLVGYTPFSGNSTNETYENLRNWKHVLQRPKCDNGRYAFSDRTWELITRLIADPINR 459
+FE L G PF G ET ++ + K ++ ++ L +P NR
Sbjct: 252 MFEMLTGSLPFQGKDRKETMT-------LILKAKLGMPQFLSTEAQSLLRALFKRNPANR 304
Query: 460 LKS----FEHVKRMRYFSEIDFNTL--RTIHPPFIPQLDNEEDVGYFD-DFTN 505
L S E +KR ++S ID+N L R I PPF P + +D YFD +FT+
Sbjct: 305 LGSGPDGAEEIKRHVFYSTIDWNKLYRREIKPPFKPAVAQPDDTFYFDTEFTS 357
Score = 77.8 bits (190), Expect = 4e-14
Identities = 59/242 (24%), Positives = 101/242 (41%), Gaps = 53/242 (21%)
Query: 232 LVKLLYAFQDPQSLYLAMEFVPGGDFRTLLLNTKFLQAPHARFYISEMFCAVNALHQLGY 291
++ L + D + +YL E + GG+ +L KF A F + + V LH G
Sbjct: 472 IITLKDVYDDGKHVYLVTELMRGGELLDKILRQKFFSEREASFVLHTIGKTVEYLHSQGV 531
Query: 292 THRDLKPENFL-IDSKGH---IKLTDFGLASGTVSMERIESMKIRLQEVKNLEFPEFRER 347
HRDLKP N L +D G+ +++ DFG A
Sbjct: 532 VHRDLKPSNILYVDESGNPECLRICDFGFA------------------------------ 561
Query: 348 SMDDRRRMYNKLREEEVRYAHSTVGSPDYMALEVLEAKNYDFTVDYWSLGCILFESLVGY 407
+LR E + + +++A EVL+ + YD D WSLG +L+ L GY
Sbjct: 562 ---------KQLRAEN-GLLMTPCYTANFVAPEVLKRQGYDEGCDIWSLGILLYTMLAGY 611
Query: 408 TPFSGNSTNETYENLRNWKHVLQRPKCDNGRYAFSDRTWELITRLIADPINRLKSFEHVK 467
TPF+ N ++T E + + +G++ S W ++ D ++++ + +
Sbjct: 612 TPFA-NGPSDTPEEILT--------RIGSGKFTLSGGNWNTVSETAKDLVSKMLHVDPHQ 662
Query: 468 RM 469
R+
Sbjct: 663 RL 664
>CE18169 [T] KOG0603 Ribosomal protein S6 kinase
Length = 797
Score = 145 bits (367), Expect = 1e-34
Identities = 114/370 (30%), Positives = 161/370 (42%), Gaps = 62/370 (16%)
Query: 149 WQGYLTKETNI----LRKRRLKPKHKDFEMITXXXXXXXXXXXLARK---KDTKEICAXX 201
W+ + ET I +RK K + FE++ L RK +D+ + A
Sbjct: 77 WKTDSSSETEIDIGDVRKCGEKADPRQFELLKVLGQGSFGKVFLVRKVRGRDSGHVYAMK 136
Query: 202 XXXXXXXXXXEGTDHVLTERDILTTTRSEWLVKLLYAFQDPQSLYLAMEFVPGGDFRTLL 261
+ ER+IL ++VKL YAFQ LYL ++F+ GGD T L
Sbjct: 137 VLKKATLKVRD-RQRTKLERNILAHISHPFIVKLHYAFQTEGKLYLILDFLRGGDLFTRL 195
Query: 262 LNTKFLQAPHARFYISEMFCAVNALHQLGYTHRDLKPENFLIDSKGHIKLTDFGLASGTV 321
+FY++E+ A+ LH LG +RDLKPEN L+D+ GHIK+TDFGL
Sbjct: 196 SKEVMFTEDDVKFYLAELTLALEHLHSLGIVYRDLKPENILLDADGHIKVTDFGL----- 250
Query: 322 SMERIESMKIRLQEVKNLEFPEFRERSMDDRRRMYNKLREEEVRYAHSTVGSPDYMALEV 381
S E I+S K +S G+ +YMA EV
Sbjct: 251 SKEAIDSEK-----------------------------------KTYSFCGTVEYMAPEV 275
Query: 382 LEAKNYDFTVDYWSLGCILFESLVGYTPFSGNSTNETYENLRNWK----HVLQRPKCDNG 437
+ + + D+WSLG ++FE L G+ PF G N+T + K H L +
Sbjct: 276 INRRGHSMAADFWSLGVLMFEMLTGHLPFQGRDRNDTMTQILKAKLSMPHFLTQEAQSLL 335
Query: 438 RYAFSDRTWELITRLIADPINRLKSFEHVKRMRYFSEIDFNTL--RTIHPPFIPQLDNEE 495
R F + RL A P E +KR +F++IDF L + I PPF P L +
Sbjct: 336 RALFKRNSQ---NRLGAGP----DGVEEIKRHAFFAKIDFVKLLNKEIDPPFKPALSTVD 388
Query: 496 DVGYFD-DFT 504
YFD +FT
Sbjct: 389 STSYFDPEFT 398
>7293249 [T] KOG0612 Rho-associated coiled-coil containing protein kinase
Length = 1390
Score = 145 bits (366), Expect = 2e-34
Identities = 98/352 (27%), Positives = 159/352 (44%), Gaps = 52/352 (14%)
Query: 164 RLKPKHKDFEMITXXXXXXXXXXXLARKKDTKEICAXXXXXXXXXXXXEGTDHVLTERDI 223
+L+ +DF I L R K + ++ A + ER I
Sbjct: 79 QLRMNVEDFHFIKLIGAGAFGEVQLVRHKSSSQVYAMKRLSKFEMMKRPDSAFFWEERHI 138
Query: 224 LTTTRSEWLVKLLYAFQDPQSLYLAMEFVPGGDFRTLLLNTKFLQAPHARFYISEMFCAV 283
+ SEW+V+L +AFQD + LY+ M+F+PGGD +L+ + + A FY E+ A+
Sbjct: 139 MAHANSEWIVQLHFAFQDAKYLYMVMDFMPGGDIVSLMGDYD-IPEKWAIFYTMEVVLAL 197
Query: 284 NALHQLGYTHRDLKPENFLIDSKGHIKLTDFGLASGTVSMERIESMKIRLQEVKNLEFPE 343
+ +H +G+ HRD+KP+N L+DS GH+KL DFG + ++ S
Sbjct: 198 DTIHNMGFVHRDVKPDNMLLDSYGHLKLADFGTCMRMGANGQVVS--------------- 242
Query: 344 FRERSMDDRRRMYNKLREEEVRYAHSTVGSPDYMALEVLEAK----NYDFTVDYWSLGCI 399
+ VG+PDY++ EVL+++ Y D+WS+G
Sbjct: 243 ------------------------SNAVGTPDYISPEVLQSQGVDNEYGRECDWWSVGIF 278
Query: 400 LFESLVGYTPFSGNSTNETYENLRNWKHVLQRPKCDNGRYAFSDRTWELITRLIADPINR 459
L+E L G TPF +S TY + + K+ L P S++ LI + D R
Sbjct: 279 LYEMLFGETPFYADSLVGTYGKIMDHKNSLSFPP----EVEISEQAKALIRAFLTDRTQR 334
Query: 460 LKSF--EHVKRMRYF--SEIDFNTLRTIHPPFIPQLDNEEDVGYFDDFTNEE 507
L + E +K +F F+ +R PP +P+L +++D F+D +E
Sbjct: 335 LGRYGIEDIKAHPFFRNDTWSFDNIRESVPPVVPELSSDDDTRNFEDIERDE 386
>CE13014 [T] KOG0603 Ribosomal protein S6 kinase
Length = 740
Score = 144 bits (364), Expect = 3e-34
Identities = 100/292 (34%), Positives = 137/292 (46%), Gaps = 54/292 (18%)
Query: 220 ERDILTTTRSEWLVKLLYAFQDPQSLYLAMEFVPGGDFRTLLLNTKFLQAPHARFYISEM 279
ER+IL ++VKL YAFQ LYL ++F+ GGD T L +FY++E+
Sbjct: 97 ERNILAHISHPFIVKLHYAFQTEGKLYLILDFLRGGDLFTRLSKEVMFTEDDVKFYLAEL 156
Query: 280 FCAVNALHQLGYTHRDLKPENFLIDSKGHIKLTDFGLASGTVSMERIESMKIRLQEVKNL 339
A+ LH LG +RDLKPEN L+D+ GHIK+TDFGL S E I+S K
Sbjct: 157 TLALEHLHSLGIVYRDLKPENILLDADGHIKVTDFGL-----SKEAIDSEK--------- 202
Query: 340 EFPEFRERSMDDRRRMYNKLREEEVRYAHSTVGSPDYMALEVLEAKNYDFTVDYWSLGCI 399
+S G+ +YMA EV+ + + D+WSLG +
Sbjct: 203 --------------------------KTYSFCGTVEYMAPEVINRRGHSMAADFWSLGVL 236
Query: 400 LFESLVGYTPFSGNSTNETYENLRNWK----HVLQRPKCDNGRYAFSDRTWELITRLIAD 455
+FE L G+ PF G N+T + K H L + R F + RL A
Sbjct: 237 MFEMLTGHLPFQGRDRNDTMTQILKAKLSMPHFLTQEAQSLLRALFKRNSQ---NRLGAG 293
Query: 456 PINRLKSFEHVKRMRYFSEIDFNTL--RTIHPPFIPQLDNEEDVGYFD-DFT 504
P E +KR +F++IDF L + I PPF P L + YFD +FT
Sbjct: 294 P----DGVEEIKRHAFFAKIDFVKLLNKEIDPPFKPALSTVDSTSYFDPEFT 341
>CE04603 [T] KOG0616 cAMP-dependent protein kinase catalytic subunit (PKA)
Length = 371
Score = 144 bits (364), Expect = 3e-34
Identities = 107/382 (28%), Positives = 176/382 (46%), Gaps = 70/382 (18%)
Query: 137 SNLMGTEQITNEWQGYLTKETNILRKRRLKPKHKDF-----EMITXXXXXXXXXXXLARK 191
+N G Q+ L +ET++ K + P + F E I LAR
Sbjct: 30 NNSRGNNQVNE-----LAEETHM--KLSITPTRESFSLSQLERIITIGKGTFGRVELARD 82
Query: 192 KDTKEICAXXXXXXXXXXXXEGTDHVLTERDILTTTRSEWLVKLLYAFQDPQSLYLAMEF 251
K T A T HV E+ +L + ++VK+ + +D LY+ MEF
Sbjct: 83 KITGAHYALKVLNIRRVVDMRQTQHVHNEKRVLLQLKHPFIVKMYASEKDSNHLYMIMEF 142
Query: 252 VPGGDFRTLLLNTKFLQAPHARFYISEMFCAVNALHQLGYTHRDLKPENFLIDSKGHIKL 311
VPGG+ + L ++ ARFY SE+ CA+ +H LG +RDLKPEN ++ +GHIK+
Sbjct: 143 VPGGEMFSYLRASRSFSNSMARFYASEIVCALEYIHSLGIVYRDLKPENLMLSKEGHIKM 202
Query: 312 TDFGLASGTVSMERIESMKIRLQEVKNLEFPEFRERSMDDRRRMYNKLREEEVRYAHSTV 371
DFG A E R+R+ ++
Sbjct: 203 ADFGFAK------------------------ELRDRT-------------------YTIC 219
Query: 372 GSPDYMALEVLEAKNYDFTVDYWSLGCILFESLVGYTPFSGNSTNETYENLRNWKHVLQR 431
G+PDY+A E L ++ VD+W+LG +++E +VG PF G +T+E Y+ + +H L+
Sbjct: 220 GTPDYLAPESLARTGHNKGVDWWALGILIYEMMVGKPPFRGKTTSEIYDAI--IEHKLKF 277
Query: 432 PKCDNGRYAFSDRTWELITRLI-ADPINRL----KSFEHVKRMRYFSEIDF-NTLR-TIH 484
P+ +F+ +L+ +L+ D R+ + VK ++F ++++ +TL +
Sbjct: 278 PR------SFNLAAKDLVKKLLEVDRTQRIGCMKNGTQDVKDHKWFEKVNWDDTLHLRVE 331
Query: 485 PPFIPQLDNEEDVGYFDDFTNE 506
PP +P L + D G FDD+ +
Sbjct: 332 PPIVPTLYHPGDTGNFDDYEED 353
>YMR104c [RT] KOG0598 Ribosomal protein S6 kinase and related proteins
Length = 677
Score = 144 bits (363), Expect = 4e-34
Identities = 108/380 (28%), Positives = 169/380 (44%), Gaps = 62/380 (16%)
Query: 171 DFEMITXXXXXXXXXXXLARKKDTKEICAXXXXXXXXXXXXEGTDHVLTERDILTTTRSE 230
DF+++ RKKDT++I A H L ER +L
Sbjct: 343 DFDLLKVIGKGSFGKVMQVRKKDTQKIYALKALRKAYIVSKCEVTHTLAERTVLARVDCP 402
Query: 231 WLVKLLYAFQDPQSLYLAMEFVPGGDFRTLLLNTKFLQAPHARFYISEMFCAVNALHQLG 290
++V L ++FQ P+ LYL + F+ GG+ L + +RFYI+E+ CA+++LH+L
Sbjct: 403 FIVPLKFSFQSPEKLYLVLAFINGGELFYHLQHEGRFSLARSRFYIAELLCALDSLHKLD 462
Query: 291 YTHRDLKPENFLIDSKGHIKLTDFGLASGTVSMERIESMKIRLQEVKNLEFPEFRERSMD 350
+RDLKPEN L+D +GHI L DFGL
Sbjct: 463 VIYRDLKPENILLDYQGHIALCDFGLC--------------------------------- 489
Query: 351 DRRRMYNKLREEEVRYAHSTVGSPDYMALEVLEAKNYDFTVDYWSLGCILFESLVGYTPF 410
KL ++ + G+P+Y+A E+L + Y TVD+W+LG +L+E + G P+
Sbjct: 490 -------KLNMKDNDKTDTFCGTPEYLAPEILLGQGYTKTVDWWTLGILLYEMMTGLPPY 542
Query: 411 SGNSTNETYENLRNWKHVLQRPKC--DNGRYAFSDRTWELITRLIADPINRL--KSFEHV 466
+ Y K +LQ+P D A D L++R DP RL + +
Sbjct: 543 YDENVPVMY------KKILQQPLLFPDGFDPAAKDLLIGLLSR---DPSRRLGVNGTDEI 593
Query: 467 KRMRYFSEIDFN--TLRTIHPPFIPQLDNEEDVGYFD-DFTNEEHMARYVDVF------K 517
+ +F +I + L+ PP+ P + +E D FD +FT E+ + VD + K
Sbjct: 594 RNHPFFKDISWKKLLLKGYIPPYKPIVKSEIDTANFDQEFTKEKPIDSVVDEYLSASIQK 653
Query: 518 RQDRLTAMVDDSLSDSKLVG 537
+ T + D+ L DS G
Sbjct: 654 QFGGWTYIGDEQLGDSPSQG 673
>ECU01g1320 [T] KOG0612 Rho-associated coiled-coil containing protein kinase
Length = 865
Score = 144 bits (363), Expect = 4e-34
Identities = 89/278 (32%), Positives = 135/278 (48%), Gaps = 53/278 (19%)
Query: 229 SEWLVKLLYAFQDPQSLYLAMEFVPGGDFRTLLLNTKFLQAPHARFYISEMFCAVNALHQ 288
SEWLV QD + LY M+F+PGGDF LL L+ RFY +E+ A++ LH+
Sbjct: 100 SEWLVCAHMTMQDEEYLYYLMDFIPGGDFMGLLSKEDVLEEDWVRFYAAEIVAALDELHK 159
Query: 289 LGYTHRDLKPENFLIDSKGHIKLTDFGLASGTVSMERIESMKIRLQEVKNLEFPEFRERS 348
LG+ HRDLKP+N LI GH+KL DFG
Sbjct: 160 LGWIHRDLKPDNVLIGIDGHVKLADFGSCI------------------------------ 189
Query: 349 MDDRRRMYNKLREEEVRYAHSTVGSPDYMALEVL----EAKNYDFTVDYWSLGCILFESL 404
K+++ + R + TVG+PDY++ +VL E Y VD+W+LG I++E +
Sbjct: 190 ---------KMKDGKAR-SSITVGTPDYVSPDVLCSVNEECEYGEDVDFWTLGVIIYEMI 239
Query: 405 VGYTPFSGNSTNETYENLRNWKHVLQRPKCDNGRYAFSDRTWELITRLIADPINRLKSFE 464
G TPF ++ ETY + + + S LI LIA R++ E
Sbjct: 240 YGTTPFYSDTLMETYRRITRVEFGFP--------FKVSPELTSLIEGLIAAKDRRMR-IE 290
Query: 465 HVKRMRYFSEIDFNTLRTIHPPFIPQLDNEEDVGYFDD 502
+K +F +D++ L+ + PPF+P+++ + D +F D
Sbjct: 291 EIKSHAFFEGVDWSRLKELKPPFVPEVNGDSDTSHFVD 328
>Hs19923570 [T] KOG0603 Ribosomal protein S6 kinase
Length = 733
Score = 144 bits (362), Expect = 5e-34
Identities = 97/292 (33%), Positives = 139/292 (47%), Gaps = 54/292 (18%)
Query: 220 ERDILTTTRSEWLVKLLYAFQDPQSLYLAMEFVPGGDFRTLLLNTKFLQAPHARFYISEM 279
ERDIL ++VKL YAFQ LYL ++F+ GGD T L +FY++E+
Sbjct: 109 ERDILAEVNHPFIVKLHYAFQTEGKLYLILDFLRGGDLFTRLSKEVMFTEEDVKFYLAEL 168
Query: 280 FCAVNALHQLGYTHRDLKPENFLIDSKGHIKLTDFGLASGTVSMERIESMKIRLQEVKNL 339
A++ LH LG +RDLKPEN L+D +GHIK+TDFGL+
Sbjct: 169 ALALDHLHSLGIIYRDLKPENILLDEEGHIKITDFGLS---------------------- 206
Query: 340 EFPEFRERSMDDRRRMYNKLREEEVRYAHSTVGSPDYMALEVLEAKNYDFTVDYWSLGCI 399
+E D+R A+S G+ +YMA EV+ + + + D+WS G +
Sbjct: 207 -----KEAIDHDKR-------------AYSFCGTIEYMAPEVVNRRGHTQSADWWSFGVL 248
Query: 400 LFESLVGYTPFSGNSTNETYENLRNWKHVLQRPKCDNGRYAFSDRTWELITRLIADPINR 459
+FE L G PF G ET ++ + K ++ + L +P NR
Sbjct: 249 MFEMLTGSLPFQGKDRKETMA-------LILKAKLGMPQFLSGEAQSLLRALFKRNPCNR 301
Query: 460 L----KSFEHVKRMRYFSEIDFNTL--RTIHPPFIPQLDNEEDVGYFD-DFT 504
L E +KR +F ID+NTL + I PPF P + ED +FD +FT
Sbjct: 302 LGAGIDGVEEIKRHPFFVTIDWNTLYRKEIKPPFKPAVGRPEDTFHFDPEFT 353
Score = 74.7 bits (182), Expect = 3e-13
Identities = 59/246 (23%), Positives = 103/246 (40%), Gaps = 61/246 (24%)
Query: 232 LVKLLYAFQDPQSLYLAMEFVPGGDFRTLLLNTKFLQAPHARFYISEMFCAVNALHQLGY 291
++ L + D + +YL ME + GG+ +L ++ A + + ++ LH G
Sbjct: 469 IITLKDVYDDGKFVYLVMELMRGGELLDRILRQRYFSEREASDVLCTITKTMDYLHSQGV 528
Query: 292 THRDLKPENFLI-DSKGH---IKLTDFGLASGTVSMERIESMKIRLQEVKNLEFPEFRER 347
HRDLKP N L D G I++ DFG A
Sbjct: 529 VHRDLKPSNILYRDESGSPESIRVCDFGFA------------------------------ 558
Query: 348 SMDDRRRMYNKLREEEVRYAHSTVGSPDY----MALEVLEAKNYDFTVDYWSLGCILFES 403
+++R + + +P Y +A EVL+ + YD D WSLG +L+
Sbjct: 559 --------------KQLRAGNGLLMTPCYTANFVAPEVLKRQGYDAACDIWSLGILLYTM 604
Query: 404 LVGYTPFSGNSTNETYENLRNWKHVLQRPKCDNGRYAFSDRTWELITRLIADPINRLKSF 463
L G+TPF+ N ++T E + + +G+YA S W+ I+ D ++++
Sbjct: 605 LAGFTPFA-NGPDDTPEEI--------LARIGSGKYALSGGNWDSISDAAKDVVSKMLHV 655
Query: 464 EHVKRM 469
+ +R+
Sbjct: 656 DPHQRL 661
>SPCC24B10.07 [RT] KOG0598 Ribosomal protein S6 kinase and related proteins
Length = 569
Score = 143 bits (361), Expect = 6e-34
Identities = 103/342 (30%), Positives = 148/342 (43%), Gaps = 56/342 (16%)
Query: 172 FEMITXXXXXXXXXXXLARKKDTKEICAXXXXXXXXXXXXEGTDHVLTERDILTTTRSEW 231
FE++ RK+DT I A DH L ER +L + +
Sbjct: 230 FELLKVVGKGSFGKVMQVRKRDTSRIYALKTMKKAHIVSRSEVDHTLAERTVLAQVNNPF 289
Query: 232 LVKLLYAFQDPQSLYLAMEFVPGGDFRTLLLNTKFLQAPHARFYISEMFCAVNALHQLGY 291
+V L ++FQ P LYL + FV GG+ L A+FYI+E+ A+ LH+
Sbjct: 290 IVPLKFSFQSPGKLYLVLAFVNGGELFHHLQREGCFDTYRAKFYIAELLVALECLHEFNV 349
Query: 292 THRDLKPENFLIDSKGHIKLTDFGLASGTVSMERIESMKIRLQEVKNLEFPEFRERSMDD 351
+RDLKPEN L+D GHI L DFGL
Sbjct: 350 IYRDLKPENILLDYTGHIALCDFGLC---------------------------------- 375
Query: 352 RRRMYNKLREEEVRYAHSTVGSPDYMALEVLEAKNYDFTVDYWSLGCILFESLVGYTPFS 411
KL + ++ G+P+Y+A E+L Y VD+W+LG +L+E + G PF
Sbjct: 376 ------KLNMAKTDRTNTFCGTPEYLAPELLLGHGYTKVVDWWTLGVLLYEMITGLPPFY 429
Query: 412 GNSTNETYENLRNWKHVLQRPK--CDNGRYAFSDRTWELITRLIADPINRLKS--FEHVK 467
+ NE Y + +LQ P DN D L+TR P RL S + +K
Sbjct: 430 DENINEMY------RKILQDPLRFPDNIDEKAKDLLSGLLTRA---PEKRLGSGGAQEIK 480
Query: 468 RMRYFSEIDFNTL--RTIHPPFIPQLDNEEDVGYFD-DFTNE 506
+F +ID+ L + I PPF P +++ D FD +FT+E
Sbjct: 481 NHPFFDDIDWKKLCAKKIQPPFKPSVESAIDTSNFDSEFTSE 522
>CE27166 [T] KOG0616 cAMP-dependent protein kinase catalytic subunit (PKA)
Length = 270
Score = 142 bits (359), Expect = 1e-33
Identities = 90/300 (30%), Positives = 152/300 (50%), Gaps = 58/300 (19%)
Query: 214 TDHVLTERDILTTTRSEWLVKLLYAFQDPQSLYLAMEFVPGGDFRTLLLNTKFLQAPHAR 273
T HV E+ +L + ++VK+ + +D LY+ MEFVPGG+ + L ++ AR
Sbjct: 4 TQHVHNEKRVLLQLKHPFIVKMYASEKDSNHLYMIMEFVPGGEMFSYLRASRSFSNSMAR 63
Query: 274 FYISEMFCAVNALHQLGYTHRDLKPENFLIDSKGHIKLTDFGLASGTVSMERIESMKIRL 333
FY SE+ CA+ +H LG +RDLKPEN ++ +GHIK+ DFG A
Sbjct: 64 FYASEIVCALEYIHSLGIVYRDLKPENLMLSKEGHIKMADFGFAK--------------- 108
Query: 334 QEVKNLEFPEFRERSMDDRRRMYNKLREEEVRYAHSTVGSPDYMALEVLEAKNYDFTVDY 393
E R+R+ ++ G+PDY+A E L ++ VD+
Sbjct: 109 ---------ELRDRT-------------------YTICGTPDYLAPESLARTGHNKGVDW 140
Query: 394 WSLGCILFESLVGYTPFSGNSTNETYENLRNWKHVLQRPKCDNGRYAFSDRTWELITRLI 453
W+LG +++E +VG PF G +T+E Y+ + +H L+ P+ +F+ +L+ +L+
Sbjct: 141 WALGILIYEMMVGKPPFRGKTTSEIYDAI--IEHKLKFPR------SFNLAAKDLVKKLL 192
Query: 454 -ADPINRL----KSFEHVKRMRYFSEIDF-NTLR-TIHPPFIPQLDNEEDVGYFDDFTNE 506
D R+ + VK ++F ++++ +TL + PP +P L + D G FDD+ +
Sbjct: 193 EVDRTQRIGCMKNGTQDVKDHKWFEKVNWDDTLHLRVEPPIVPTLYHPGDTGNFDDYEED 252
>Hs20127541 [RT] KOG0598 Ribosomal protein S6 kinase and related proteins
Length = 427
Score = 141 bits (356), Expect = 2e-33
Identities = 103/343 (30%), Positives = 154/343 (44%), Gaps = 54/343 (15%)
Query: 171 DFEMITXXXXXXXXXXXLARKKDTKEICAXXXXXXXXXXXXEGTDHVLTERDILT-TTRS 229
DF+ + LA++K A + H++ ER +L R
Sbjct: 94 DFDFLKVIGKGNYGKVLLAKRKSDGAFYAVKVLQKKSILKKKEQSHIMAERSVLLKNVRH 153
Query: 230 EWLVKLLYAFQDPQSLYLAMEFVPGGD-FRTLLLNTKFLQAPHARFYISEMFCAVNALHQ 288
+LV L Y+FQ P+ LY +++V GG+ F L +FL+ P ARFY +E+ A+ LH
Sbjct: 154 PFLVGLRYSFQTPEKLYFVLDYVNGGELFFHLQRERRFLE-PRARFYAAEVASAIGYLHS 212
Query: 289 LGYTHRDLKPENFLIDSKGHIKLTDFGLASGTVSMERIESMKIRLQEVKNLEFPEFRERS 348
L +RDLKPEN L+D +GH+ LTDFGL V E S
Sbjct: 213 LNIIYRDLKPENILLDCQGHVVLTDFGLCKEGVEPEDTTS-------------------- 252
Query: 349 MDDRRRMYNKLREEEVRYAHSTVGSPDYMALEVLEAKNYDFTVDYWSLGCILFESLVGYT 408
+ G+P+Y+A EVL + YD VD+W LG +L+E L G
Sbjct: 253 --------------------TFCGTPEYLAPEVLRKEPYDRAVDWWCLGAVLYEMLHGLP 292
Query: 409 PFSGNSTNETYENLRNWKHVLQRP-KCDNGR-YAFSDRTWELITRLIADPINRLKSFEHV 466
PF ++ YEN +L +P + GR A D L+ + + F +
Sbjct: 293 PFYSQDVSQMYEN------ILHQPLQIPGGRTVAACDLLQSLLHKDQRQRLGSKADFLEI 346
Query: 467 KRMRYFSEIDFNTL--RTIHPPFIPQLDNEEDVGYFD-DFTNE 506
K +FS I+++ L + + PPF P + D+ +FD +FT E
Sbjct: 347 KNHVFFSPINWDDLYHKRLTPPFNPNVTGPADLKHFDPEFTQE 389
>YKL126w [RT] KOG0598 Ribosomal protein S6 kinase and related proteins
Length = 680
Score = 140 bits (353), Expect = 5e-33
Identities = 99/351 (28%), Positives = 154/351 (43%), Gaps = 52/351 (14%)
Query: 171 DFEMITXXXXXXXXXXXLARKKDTKEICAXXXXXXXXXXXXEGTDHVLTERDILTTTRSE 230
DF+++ RKKDT+++ A H L ER +L
Sbjct: 346 DFDLLKVIGKGSFGKVMQVRKKDTQKVYALKAIRKSYIVSKSEVTHTLAERTVLARVDCP 405
Query: 231 WLVKLLYAFQDPQSLYLAMEFVPGGDFRTLLLNTKFLQAPHARFYISEMFCAVNALHQLG 290
++V L ++FQ P+ LY + F+ GG+ L ARFY +E+ CA++ LH+L
Sbjct: 406 FIVPLKFSFQSPEKLYFVLAFINGGELFYHLQKEGRFDLSRARFYTAELLCALDNLHKLD 465
Query: 291 YTHRDLKPENFLIDSKGHIKLTDFGLASGTVSMERIESMKIRLQEVKNLEFPEFRERSMD 350
+RDLKPEN L+D +GHI L DFGL K+ +++ D
Sbjct: 466 VVYRDLKPENILLDYQGHIALCDFGLC------------KLNMKD--------------D 499
Query: 351 DRRRMYNKLREEEVRYAHSTVGSPDYMALEVLEAKNYDFTVDYWSLGCILFESLVGYTPF 410
D+ + G+P+Y+A E+L Y VD+W+LG +L+E L G P+
Sbjct: 500 DKTDTF--------------CGTPEYLAPELLLGLGYTKAVDWWTLGVLLYEMLTGLPPY 545
Query: 411 SGNSTNETYENLRNWKHVLQRPKCDNGRYAFSDRTWELITRLIADPINRL--KSFEHVKR 468
+ Y K +LQ P + D LI L DP RL + ++
Sbjct: 546 YDEDVPKMY------KKILQEPLVFPDGFD-RDAKDLLIGLLSRDPTRRLGYNGADEIRN 598
Query: 469 MRYFSEIDFNTL--RTIHPPFIPQLDNEEDVGYFD-DFTNEEHMARYVDVF 516
+FS++ + L + PP+ P + N D FD +FT E+ + VD +
Sbjct: 599 HPFFSQLSWKRLLMKGYIPPYKPAVSNSMDTSNFDEEFTREKPIDSVVDEY 649
>SPCC4G3.08 [RT] KOG0598 Ribosomal protein S6 kinase and related proteins
Length = 436
Score = 140 bits (353), Expect = 5e-33
Identities = 105/361 (29%), Positives = 162/361 (44%), Gaps = 60/361 (16%)
Query: 154 TKETNILRKRRLKPKHKDFEMITXXXXXXXXXXXLARKKDTKEICAXXXXXXXXXXX-XE 212
+K N + +++P DF+ +T L ++K+T + A +
Sbjct: 75 SKGDNYVPSGKMRPA--DFQPLTVLGRGSYGKVLLVKQKNTGRLFAQKQLKKASIVLRAK 132
Query: 213 GTDHVLTERDILTTTRSEWLVKLLYAFQDPQSLYLAMEFVPGGDFRTLLLNTKFLQAPHA 272
G + ER IL R ++ +L YAFQD LYL +++ PGG+ + L + L
Sbjct: 133 GLEQTKNERQILEEVRHPFICRLYYAFQDHDRLYLILQYAPGGELFSHLAEQRMLPEDVV 192
Query: 273 RFYISEMFCAVNALHQLGYTHRDLKPENFLIDSKGHIKLTDFGLASGTVSMERIESMKIR 332
FY +E+ A+ LH+LG +RDLKPEN L+D++GHI LTDFGL+
Sbjct: 193 AFYTAELTLALIHLHKLGIVYRDLKPENCLLDAEGHILLTDFGLS--------------- 237
Query: 333 LQEVKNLEFPEFRERSMDDRRRMYNKLREEEVRYAHSTVGSPDYMALEVLEAKNYDFTVD 392
+ E D R S VG+ +Y A E+L + YD VD
Sbjct: 238 ----------KVAENGADCR----------------SFVGTEEYCAPEILLEQPYDHAVD 271
Query: 393 YWSLGCILFESLVGYTPFSGNSTNETYENLRNWKHVLQRPKCDNGRYAFSDRTWELITRL 452
+WS+G ++F+ L G PF+ N+ E + R K + Y SD + L
Sbjct: 272 WWSMGILIFDLLTGSPPFTANNHKRIMEK-------ITRAKPNIPFYVTSDARDIINKFL 324
Query: 453 IADPINRL------KSFEHVKRMRYFSEIDFNTL--RTIHPPFIPQLDNEEDVGYFD-DF 503
+P RL K ++ +K+ R + ID+N L R + PP +P + N E F +F
Sbjct: 325 KKNPKQRLGADGPEKGYDAIKKHRIYRRIDWNKLEKRMLPPPIVPCITNPEAAENFSVEF 384
Query: 504 T 504
T
Sbjct: 385 T 385
>Hs5032091 [RT] KOG0598 Ribosomal protein S6 kinase and related proteins
Length = 431
Score = 140 bits (353), Expect = 5e-33
Identities = 102/376 (27%), Positives = 162/376 (42%), Gaps = 49/376 (13%)
Query: 168 KHKDFEMITXXXXXXXXXXXLARKKDTKEICAXXXXXXXXXXXXEGTDHVLTERDILT-T 226
K DF + LAR K + A + H+++ER++L
Sbjct: 94 KPSDFHFLKVIGKGSFGKVLLARHKAEEVFYAVKVLQKKAILKKKEEKHIMSERNVLLKN 153
Query: 227 TRSEWLVKLLYAFQDPQSLYLAMEFVPGGDFRTLLLNTKFLQAPHARFYISEMFCAVNAL 286
+ +LV L ++FQ LY ++++ GG+ L + P ARFY +E+ A+ L
Sbjct: 154 VKHPFLVGLHFSFQTADKLYFVLDYINGGELFYHLQRERCFLEPRARFYAAEIASALGYL 213
Query: 287 HQLGYTHRDLKPENFLIDSKGHIKLTDFGLASGTVSMERIESMKIRLQEVKNLEFPEFRE 346
H L +RDLKPEN L+DS+GHI LTDFGL + S
Sbjct: 214 HSLNIVYRDLKPENILLDSQGHIVLTDFGLCKENIEHNSTTS------------------ 255
Query: 347 RSMDDRRRMYNKLREEEVRYAHSTVGSPDYMALEVLEAKNYDFTVDYWSLGCILFESLVG 406
+ G+P+Y+A EVL + YD TVD+W LG +L+E L G
Sbjct: 256 ----------------------TFCGTPEYLAPEVLHKQPYDRTVDWWCLGAVLYEMLYG 293
Query: 407 YTPFSGNSTNETYENLRNWKHVLQRPKCDNGRYAFSDRTWELITRLIADPINRLKSFEHV 466
PF +T E Y+N+ N K + +P N + L+ + + F +
Sbjct: 294 LPPFYSRNTAEMYDNILN-KPLQLKPNITNSARHLLE---GLLQKDRTKRLGAKDDFMEI 349
Query: 467 KRMRYFSEIDFNTL--RTIHPPFIPQLDNEEDVGYFDDFTNEEHMARYVDVFKRQDRLTA 524
K +FS I+++ L + I PPF P + ++ +FD EE + + +TA
Sbjct: 350 KSHVFFSLINWDDLINKKITPPFNPNVSGPNELRHFDPEFTEEPVPNSIGKSPDSVLVTA 409
Query: 525 MVDDSLSDSKLVGFTF 540
V ++ +GF++
Sbjct: 410 SVKEAA--EAFLGFSY 423
>YKL166c [T] KOG0616 cAMP-dependent protein kinase catalytic subunit (PKA)
Length = 398
Score = 140 bits (352), Expect = 7e-33
Identities = 94/341 (27%), Positives = 157/341 (45%), Gaps = 51/341 (14%)
Query: 171 DFEMITXXXXXXXXXXXLARKKDTKEICAXXXXXXXXXXXXEGTDHVLTERDILTTTRSE 230
DF+++ L R A + +H ER +L+
Sbjct: 87 DFQILRTLGTGSFGRVHLIRSNHNGRFYALKTLKKHTIVKLKQVEHTNDERRMLSIVSHP 146
Query: 231 WLVKLLYAFQDPQSLYLAMEFVPGGDFRTLLLNTKFLQAPHARFYISEMFCAVNALHQLG 290
+++++ FQD Q +++ M+++ GG+ +LL ++ P A+FY +E+ A+ LH
Sbjct: 147 FIIRMWGTFQDSQQVFMVMDYIEGGELFSLLRKSQRFPNPVAKFYAAEVCLALEYLHSKD 206
Query: 291 YTHRDLKPENFLIDSKGHIKLTDFGLASGTVSMERIESMKIRLQEVKNLEFPEFRERSMD 350
+RDLKPEN L+D GHIK+TDFG A +
Sbjct: 207 IIYRDLKPENILLDKNGHIKITDFGFAKYVPDV--------------------------- 239
Query: 351 DRRRMYNKLREEEVRYAHSTVGSPDYMALEVLEAKNYDFTVDYWSLGCILFESLVGYTPF 410
++ G+PDY+A EV+ K Y+ +VD+WS G +++E L GYTPF
Sbjct: 240 ----------------TYTLCGTPDYIAPEVVSTKPYNKSVDWWSFGVLIYEMLAGYTPF 283
Query: 411 SGNSTNETYENLRNWKHVLQRPKCDNGRYAFSDRTWELITRLIADPINRLKS-FEHVKRM 469
++T +TYEN+ N + L+ P + D +LITR +++ + L++ E VK
Sbjct: 284 YNSNTMKTYENILNAE--LKFPPFFHP--DAQDLLKKLITRDLSERLGNLQNGSEDVKNH 339
Query: 470 RYFSEIDFNTL--RTIHPPFIPQL-DNEEDVGYFDDFTNEE 507
+F+E+ + L R I P+ P + + D FD + EE
Sbjct: 340 PWFNEVIWEKLLARYIETPYEPPIQQGQGDTSQFDRYPEEE 380
>Hs4506057 [T] KOG0616 cAMP-dependent protein kinase catalytic subunit (PKA)
Length = 351
Score = 140 bits (352), Expect = 7e-33
Identities = 95/345 (27%), Positives = 153/345 (43%), Gaps = 58/345 (16%)
Query: 170 KDFEMITXXXXXXXXXXXLARKKDTKEICAXXXXXXXXXXXXEGTDHVLTERDILTTTRS 229
+DFE L + K T++ A + +H L E+ IL
Sbjct: 42 EDFERKKTLGTGSFGRVMLVKHKATEQYYAMKILDKQKVVKLKQIEHTLNEKRILQAVNF 101
Query: 230 EWLVKLLYAFQDPQSLYLAMEFVPGGDFRTLLLNTKFLQAPHARFYISEMFCAVNALHQL 289
+LV+L YAF+D +LY+ ME+VPGG+ + L PHARFY +++ LH L
Sbjct: 102 PFLVRLEYAFKDNSNLYMVMEYVPGGEMFSHLRRIGRFSEPHARFYAAQIVLTFEYLHSL 161
Query: 290 GYTHRDLKPENFLIDSKGHIKLTDFGLASGTVSMERIESMKIRLQEVKNLEFPEFRERSM 349
+RDLKPEN LID +G+I++TDFG A + VK +
Sbjct: 162 DLIYRDLKPENLLIDHQGYIQVTDFGFA----------------KRVKGRTW-------- 197
Query: 350 DDRRRMYNKLREEEVRYAHSTVGSPDYMALEVLEAKNYDFTVDYWSLGCILFESLVGYTP 409
+ G+P+Y+A E++ +K Y+ VD+W+LG +++E GY P
Sbjct: 198 -------------------TLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPP 238
Query: 410 FSGNSTNETYENLRNWKHVLQRPKCDNGRYAFSDRTWELITRLIADPI-----NRLKSFE 464
F + + YE + + K ++ P FS +L+ L+ + N
Sbjct: 239 FFADQPIQIYEKIVSGK--VRFPS------HFSSDLKDLLRNLLQVDLTKRFGNLKNGVS 290
Query: 465 HVKRMRYFSEIDFNTL--RTIHPPFIPQLDNEEDVGYFDDFTNEE 507
+K ++F+ D+ + R + PFIP+ D FDD+ E+
Sbjct: 291 DIKTHKWFATTDWIAIYQRKVEAPFIPKFRGSGDTSNFDDYEEED 335
>7297542 [T] KOG0616 cAMP-dependent protein kinase catalytic subunit (PKA)
Length = 353
Score = 140 bits (352), Expect = 7e-33
Identities = 94/343 (27%), Positives = 152/343 (43%), Gaps = 58/343 (16%)
Query: 171 DFEMITXXXXXXXXXXXLARKKDTKEICAXXXXXXXXXXXXEGTDHVLTERDILTTTRSE 230
DFE I + + K TK+ A + +H L E+ IL +
Sbjct: 45 DFERIKTLGTGSFGRVMIVQHKPTKDYYAMKILDKQKVVKLKQVEHTLNEKRILQAIQFP 104
Query: 231 WLVKLLYAFQDPQSLYLAMEFVPGGDFRTLLLNTKFLQAPHARFYISEMFCAVNALHQLG 290
+LV L Y F+D +LY+ +E+VPGG+ + L PH+RFY +++ A LH L
Sbjct: 105 FLVSLRYHFKDNSNLYMVLEYVPGGEMFSHLRKVGRFSEPHSRFYAAQIVLAFEYLHYLD 164
Query: 291 YTHRDLKPENFLIDSKGHIKLTDFGLASGTVSMERIESMKIRLQEVKNLEFPEFRERSMD 350
+RDLKPEN LIDS+G++K+TDFG A + VK +
Sbjct: 165 LIYRDLKPENLLIDSQGYLKVTDFGFA----------------KRVKGRTW--------- 199
Query: 351 DRRRMYNKLREEEVRYAHSTVGSPDYMALEVLEAKNYDFTVDYWSLGCILFESLVGYTPF 410
+ G+P+Y+A E++ +K Y+ VD+W+LG +++E GY PF
Sbjct: 200 ------------------TLCGTPEYLAPEIILSKGYNKAVDWWALGVLVYEMAAGYPPF 241
Query: 411 SGNSTNETYENLRNWKHVLQRPKCDNGRYAFSDRTWELITRLIADPI-----NRLKSFEH 465
+ + YE + + K ++ P F +L+ L+ + N
Sbjct: 242 FADQPIQIYEKIVSGK--VRFPS------HFGSDLKDLLRNLLQVDLTKRYGNLKAGVND 293
Query: 466 VKRMRYFSEIDFNTL--RTIHPPFIPQLDNEEDVGYFDDFTNE 506
+K ++F+ D+ + + I PFIP+ D FDD+ E
Sbjct: 294 IKNQKWFASTDWIAIFQKKIEAPFIPRCKGPGDTSNFDDYEEE 336
>Hs20070247_2 [RT] KOG0598 Ribosomal protein S6 kinase and related proteins
Length = 378
Score = 139 bits (351), Expect = 9e-33
Identities = 105/380 (27%), Positives = 167/380 (43%), Gaps = 57/380 (15%)
Query: 168 KHKDFEMITXXXXXXXXXXXLARKKDTKEICAXXXXXXXXXXXXEGTDHVLTERDILT-T 226
K DF+ + LA++K ++ A + H++ ER++L
Sbjct: 40 KPTDFDFLKVIGKGSFGKVLLAKRKLDGKVYAVKVLQKKIVLNRKEQKHIMAERNVLLKN 99
Query: 227 TRSEWLVKLLYAFQDPQSLYLAMEFVPGGDFRTLLLNTKFLQAPHARFYISEMFCAVNAL 286
+ +LV L Y+FQ + LY ++FV GG+ L + ARFY +E+ A+ L
Sbjct: 100 VKHPFLVGLHYSFQTTEKLYFVLDFVNGGELFFHLQRERSFPEHRARFYAAEIASALGYL 159
Query: 287 HQLGYTHRDLKPENFLIDSKGHIKLTDFGLASGTVSMERIESMKIRLQEVKNLEFPEFRE 346
H + +RDLKPEN L+DS GH+ LTDFGL +++ +
Sbjct: 160 HSIKIVYRDLKPENILVDSVGHVVLTDFGLCKEGIAISDTTT------------------ 201
Query: 347 RSMDDRRRMYNKLREEEVRYAHSTVGSPDYMALEVLEAKNYDFTVDYWSLGCILFESLVG 406
+ G+P+Y+A EV+ + YD TVD+W LG +L+E L G
Sbjct: 202 ----------------------TFCGTPEYLAPEVIRKQPYDNTVDWWCLGAVLYEMLYG 239
Query: 407 YTPFSGNSTNETYENLRNWKHVLQRPKCDNGRYAFSDRTWELITRLI-ADPINRL---KS 462
PF E Y+N +L +P + R S R W ++ L+ D NRL +
Sbjct: 240 LPPFYCRDVAEMYDN------ILHKPL--SLRPGVSLRAWSILEELLEKDRQNRLGAKED 291
Query: 463 FEHVKRMRYFSEIDFNTL--RTIHPPFIPQLDNEEDVGYFDDFTNEEHMARYVDVFKRQD 520
F ++ +F + + L + I PPF P + +D+ FD EE + V V
Sbjct: 292 FLEIQNHPFFESLSWADLVQKKIPPPFNPNVAGPDDIRNFDTAFTEETVPYSVCVSSDYS 351
Query: 521 RLTAMVDDSLSDSKLVGFTF 540
+ A V + +D VGF++
Sbjct: 352 IVNASVLE--ADDAFVGFSY 369
>Hs4506055 [T] KOG0616 cAMP-dependent protein kinase catalytic subunit (PKA)
Length = 351
Score = 139 bits (350), Expect = 1e-32
Identities = 95/343 (27%), Positives = 151/343 (43%), Gaps = 58/343 (16%)
Query: 172 FEMITXXXXXXXXXXXLARKKDTKEICAXXXXXXXXXXXXEGTDHVLTERDILTTTRSEW 231
FE I L + K+T A + +H L E+ IL +
Sbjct: 44 FERIKTLGTGSFGRVMLVKHKETGNHYAMKILDKQKVVKLKQIEHTLNEKRILQAVNFPF 103
Query: 232 LVKLLYAFQDPQSLYLAMEFVPGGDFRTLLLNTKFLQAPHARFYISEMFCAVNALHQLGY 291
LVKL ++F+D +LY+ ME+VPGG+ + L PHARFY +++ LH L
Sbjct: 104 LVKLEFSFKDNSNLYMVMEYVPGGEMFSHLRRIGRFSEPHARFYAAQIVLTFEYLHSLDL 163
Query: 292 THRDLKPENFLIDSKGHIKLTDFGLASGTVSMERIESMKIRLQEVKNLEFPEFRERSMDD 351
+RDLKPEN LID +G+I++TDFG A + VK +
Sbjct: 164 IYRDLKPENLLIDQQGYIQVTDFGFA----------------KRVKGRTW---------- 197
Query: 352 RRRMYNKLREEEVRYAHSTVGSPDYMALEVLEAKNYDFTVDYWSLGCILFESLVGYTPFS 411
+ G+P+Y+A E++ +K Y+ VD+W+LG +++E GY PF
Sbjct: 198 -----------------TLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFF 240
Query: 412 GNSTNETYENLRNWKHVLQRPKCDNGRYAFSDRTWELITRLIADPI-----NRLKSFEHV 466
+ + YE + + K ++ P FS +L+ L+ + N +
Sbjct: 241 ADQPIQIYEKIVSGK--VRFPS------HFSSDLKDLLRNLLQVDLTKRFGNLKNGVNDI 292
Query: 467 KRMRYFSEIDFNTL--RTIHPPFIPQLDNEEDVGYFDDFTNEE 507
K ++F+ D+ + R + PFIP+ D FDD+ EE
Sbjct: 293 KNHKWFATTDWIAIYQRKVEAPFIPKFKGPGDTSNFDDYEEEE 335
>Hs5453972 [T] KOG0694 Serine/threonine protein kinase
Length = 682
Score = 138 bits (347), Expect = 3e-32
Identities = 104/353 (29%), Positives = 157/353 (44%), Gaps = 56/353 (15%)
Query: 171 DFEMITXXXXXXXXXXXLARKKDTKEICAXXXXXXXXXXXXEGTDHVLTERDILTTTRSE 230
+FE I LAR K+T ++ A + + +TE+ IL+ R+
Sbjct: 353 NFEFIRVLGKGSFGKVMLARVKETGDLYAVKVLKKDVILLDDDVECTMTEKRILSLARNH 412
Query: 231 -WLVKLLYAFQDPQSLYLAMEFVPGGDFRTLLLNTKFLQAPHARFYISEMFCAVNALHQL 289
+L +L FQ P L+ MEFV GGD + ++ ARFY +E+ A+ LH
Sbjct: 413 PFLTQLFCCFQTPDRLFFVMEFVNGGDLMFHIQKSRRFDEARARFYAAEIISALMFLHDK 472
Query: 290 GYTHRDLKPENFLIDSKGHIKLTDFGLASGTVSMERIESMKIRLQEVKNLEFPEFRERSM 349
G +RDLK +N L+D +GH KL DFG+ + V F
Sbjct: 473 GIIYRDLKLDNVLLDHEGHCKLADFGMCKEGI-----------CNGVTTATF-------- 513
Query: 350 DDRRRMYNKLREEEVRYAHSTVGSPDYMALEVLEAKNYDFTVDYWSLGCILFESLVGYTP 409
G+PDY+A E+L+ Y VD+W++G +L+E L G+ P
Sbjct: 514 ---------------------CGTPDYIAPEILQEMLYGPAVDWWAMGVLLYEMLCGHAP 552
Query: 410 FSGNSTNETYENLRNWKHVLQRPKCDNGRYAFSDRTWELITRLIADPINRLKSF----EH 465
F + ++ +E + N + V + D T L + + +P RL S EH
Sbjct: 553 FEAENEDDLFEAILNDEVVYP-------TWLHEDATGILKSFMTKNPTMRLGSLTQGGEH 605
Query: 466 -VKRMRYFSEIDFNTL--RTIHPPFIPQLDNEEDVGYFD-DFTNEEHMARYVD 514
+ R +F EID+ L R I PPF P++ + EDV FD DF EE + +D
Sbjct: 606 AILRHPFFKEIDWAQLNHRQIEPPFRPRIKSREDVSNFDPDFIKEEPVLTPID 658
>YJL164c [T] KOG0616 cAMP-dependent protein kinase catalytic subunit (PKA)
Length = 397
Score = 137 bits (345), Expect = 4e-32
Identities = 92/343 (26%), Positives = 156/343 (44%), Gaps = 51/343 (14%)
Query: 169 HKDFEMITXXXXXXXXXXXLARKKDTKEICAXXXXXXXXXXXXEGTDHVLTERDILTTTR 228
+K+F+++ L R + A + +H ER +L+
Sbjct: 84 YKNFQILRTLGTGSFGRVHLIRSRHNGRYYAMKVLKKEIVVRLKQVEHTNDERLMLSIVT 143
Query: 229 SEWLVKLLYAFQDPQSLYLAMEFVPGGDFRTLLLNTKFLQAPHARFYISEMFCAVNALHQ 288
+++++ FQD Q +++ M+++ GG+ +LL ++ P A+FY +E+ A+ LH
Sbjct: 144 HPFIIRMWGTFQDAQQIFMIMDYIEGGELFSLLRKSQRFPNPVAKFYAAEVCLALEYLHS 203
Query: 289 LGYTHRDLKPENFLIDSKGHIKLTDFGLASGTVSMERIESMKIRLQEVKNLEFPEFRERS 348
+RDLKPEN L+D GHIK+TDFG A +
Sbjct: 204 KDIIYRDLKPENILLDKNGHIKITDFGFAKYVPDV------------------------- 238
Query: 349 MDDRRRMYNKLREEEVRYAHSTVGSPDYMALEVLEAKNYDFTVDYWSLGCILFESLVGYT 408
++ G+PDY+A EV+ K Y+ ++D+WS G +++E L GYT
Sbjct: 239 ------------------TYTLCGTPDYIAPEVVSTKPYNKSIDWWSFGILIYEMLAGYT 280
Query: 409 PFSGNSTNETYENLRNWKHVLQRPKCDNGRYAFSDRTWELITRLIADPINRLKS-FEHVK 467
PF ++T +TYE + N + L+ P N D LITR ++ + L++ E VK
Sbjct: 281 PFYDSNTMKTYEKILNAE--LRFPPFFN--EDVKDLLSRLITRDLSQRLGNLQNGTEDVK 336
Query: 468 RMRYFSEIDFNTL--RTIHPPFIPQL-DNEEDVGYFDDFTNEE 507
+F E+ + L R I P+ P + + D FD + E+
Sbjct: 337 NHPWFKEVVWEKLLSRNIETPYEPPIQQGQGDTSQFDKYPEED 379
>CE14798 [RT] KOG0598 Ribosomal protein S6 kinase and related proteins
Length = 422
Score = 136 bits (343), Expect = 7e-32
Identities = 97/337 (28%), Positives = 149/337 (43%), Gaps = 63/337 (18%)
Query: 171 DFEMITXXXXXXXXXXXLARKKDTKEICAXXXXXXXXXXXXEGTDHVLTERDILTTT-RS 229
DF+ +T R K+TK+I A HV+ ER++L +
Sbjct: 93 DFDYLTTIGKGSFGRVYQVRHKETKKIYAMKILSKEHIRKKNEVKHVMAERNVLINNFKH 152
Query: 230 EWLVKLLYAFQDPQSLYLAMEFVPGGDFRTLLLNTKFLQAPHARFYISEMFCAVNALHQL 289
+LV L ++FQ+ + LY ++ + GG+ + L K +RFY +E+ CA+ LH+
Sbjct: 153 PFLVSLHFSFQNKEKLYFVLDHLNGGELFSHLQREKHFSESRSRFYAAEIACALGYLHEK 212
Query: 290 GYTHRDLKPENFLIDSKGHIKLTDFGLASGTVSMERIESMKIRLQEVKNLEFPEFRERSM 349
+RDLKPEN L+D KG++ LTDFGL + + S
Sbjct: 213 NIIYRDLKPENLLLDDKGYLVLTDFGLCKEDMQGSKTTS--------------------- 251
Query: 350 DDRRRMYNKLREEEVRYAHSTVGSPDYMALEVLEAKNYDFTVDYWSLGCILFESLVGYTP 409
+ G+P+Y+A E++ K YD TVD+W LG +L+E + G P
Sbjct: 252 -------------------TFCGTPEYLAPEIILKKPYDKTVDWWCLGSVLYEMIFGLPP 292
Query: 410 FSGNSTNETYENLRN----WKHVLQRPKCDNGRYAFSDRTWELITRLI-ADPINRL---K 461
F NE Y+ + N KH + P C ELIT L+ D RL
Sbjct: 293 FYSKDHNEMYDKIINQPLRLKHNISVP-CS-----------ELITGLLQKDRSKRLGHRN 340
Query: 462 SFEHVKRMRYFSEIDFNTL--RTIHPPFIPQLDNEED 496
F ++ +F +D++ L R + PFIP++ N D
Sbjct: 341 DFRDIRDHPFFLPVDWDKLLNRELKAPFIPKVKNAMD 377
>At3g08720 [RT] KOG0598 Ribosomal protein S6 kinase and related proteins
Length = 471
Score = 135 bits (341), Expect = 1e-31
Identities = 99/339 (29%), Positives = 152/339 (44%), Gaps = 57/339 (16%)
Query: 170 KDFEMITXXXXXXXXXXXLARKKDTKEICAXXXXXXXXXXXXEGTDHVLTERDILTTTRS 229
+DFE++ RKKDT EI A +++ ERDILT
Sbjct: 138 EDFEVLKVVGQGAFGKVYQVRKKDTSEIYAMKVMRKDKIVEKNHAEYMKAERDILTKIDH 197
Query: 230 EWLVKLLYAFQDPQSLYLAMEFVPGGDFRTLLLNTKFLQAPHARFYISEMFCAVNALHQL 289
++V+L Y+FQ LYL ++F+ GG L + + AR Y +E+ AV+ LH+
Sbjct: 198 PFIVQLKYSFQTKYRLYLVLDFINGGHLFFQLYHQGLFREDLARVYTAEIVSAVSHLHEK 257
Query: 290 GYTHRDLKPENFLIDSKGHIKLTDFGLASGTVSMERIESMKIRLQEVKNLEFPEFRERSM 349
G HRDLKPEN L+D GH+ LTDFGLA EF E +
Sbjct: 258 GIMHRDLKPENILMDVDGHVMLTDFGLAK------------------------EFEENTR 293
Query: 350 DDRRRMYNKLREEEVRYAHSTVGSPDYMALEVLEAKNYDFTVDYWSLGCILFESLVGYTP 409
++S G+ +YMA E++ K +D D+WS+G +L+E L G P
Sbjct: 294 -----------------SNSMCGTTEYMAPEIVRGKGHDKAADWWSVGILLYEMLTGKPP 336
Query: 410 FSGNSTNETYENLRNWKHVLQRPKCDNGRYAFSDRTWELITRLI-ADPINRLKS----FE 464
F G+ + + K ++ P+ S+ L+ L+ +P RL S E
Sbjct: 337 FLGSKGKIQQKIV---KDKIKLPQ------FLSNEAHALLKGLLQKEPERRLGSGPSGAE 387
Query: 465 HVKRMRYFSEIDFNTL--RTIHPPFIPQLDNEEDVGYFD 501
+K+ ++F I++ L R + P F P + + + FD
Sbjct: 388 EIKKHKWFKAINWKKLEAREVQPSFKPAVSGRQCIANFD 426
>Hs15619015 [T] KOG0616 cAMP-dependent protein kinase catalytic subunit (PKA)
Length = 351
Score = 135 bits (340), Expect = 2e-31
Identities = 91/304 (29%), Positives = 141/304 (45%), Gaps = 66/304 (21%)
Query: 215 DHVLTERDILTTTRSEWLVKLLYAFQDPQSLYLAMEFVPGGDFRTLLLNTKFLQAPHARF 274
+H+L E+ IL +LVKL ++F+D LYL ME+VPGG+ + L PHA F
Sbjct: 87 EHILNEKRILQAIDFPFLVKLQFSFKDNSYLYLVMEYVPGGEMFSRLQRVGRFSEPHACF 146
Query: 275 YISEMFCAVNALHQLGYTHRDLKPENFLIDSKGHIKLTDFGLASGTVSMERIESMKIRLQ 334
Y +++ AV LH L HRDLKPEN LID +G++++TDFG A +
Sbjct: 147 YAAQVVLAVQYLHSLDLIHRDLKPENLLIDQQGYLQVTDFGFA----------------K 190
Query: 335 EVKNLEFPEFRERSMDDRRRMYNKLREEEVRYAHSTVGSPDYMALEVLEAKNYDFTVDYW 394
VK + + G+P+Y+A E++ +K Y+ VD+W
Sbjct: 191 RVKGRTW---------------------------TLCGTPEYLAPEIILSKGYNKAVDWW 223
Query: 395 SLGCILFESLVGYTPFSGNSTNETYENLRNWKHVLQRPKCDNGRYAF-----SDRTWELI 449
+LG +++E VG+ PF + + YE K +GR F SD L
Sbjct: 224 ALGVLIYEMAVGFPPFYADQPIQIYE------------KIVSGRVRFPSKLSSDLKHLLR 271
Query: 450 TRLIADPINRLKSFEH----VKRMRYFSEIDFNTL--RTIHPPFIPQLDNEEDVGYFDDF 503
+ L D R + + +K ++F+ + + + + PFIP+ D FDD+
Sbjct: 272 SLLQVDLTKRFGNLRNGVGDIKNHKWFATTSWIAIYEKKVEAPFIPKYTGPGDASNFDDY 331
Query: 504 TNEE 507
EE
Sbjct: 332 EEEE 335
>CE22045 [RT] KOG0598 Ribosomal protein S6 kinase and related proteins
Length = 580
Score = 135 bits (340), Expect = 2e-31
Identities = 90/295 (30%), Positives = 138/295 (46%), Gaps = 55/295 (18%)
Query: 214 TDHVLTERDILTTTRSEWLVKLLYAFQDPQSLYLAMEFVPGGDFRTLLLNTKFLQAPHAR 273
T H ER+IL +S ++ LLYAFQ LYL +E++ GG+ L A+
Sbjct: 129 TAHTKAERNILEAVKSPFICDLLYAFQTGGKLYLILEYLSGGELFMHLEREGMFMENVAK 188
Query: 274 FYISEMFCAVNALHQLGYTHRDLKPENFLIDSKGHIKLTDFGLASGTVSMERIESMKIRL 333
FY+SE+ ++ LHQ G +RDLKPEN L+D+ GH+KLTDFGL E IE
Sbjct: 189 FYLSEIVVSLEHLHQQGIIYRDLKPENILLDAYGHVKLTDFGLCK-----EEIEG----- 238
Query: 334 QEVKNLEFPEFRERSMDDRRRMYNKLREEEVRYAHSTVGSPDYMALEVLEAKNYDFTVDY 393
D++ H+ G+ +YMA E+L + VD+
Sbjct: 239 -----------------DQK-------------THTFCGTIEYMAPEILMRCGHGKAVDW 268
Query: 394 WSLGCILFESLVGYTPFSGNSTNETYENLRNWKHVLQRPKCDNGRYAFSDRTWELITRLI 453
WSLG ++F+ L G PF+ + +T + + + L S+ +LI +L+
Sbjct: 269 WSLGALMFDMLTGGPPFTAENRRKTIDKILKGRLTLPA--------YLSNEARDLIKKLL 320
Query: 454 ADPINR-----LKSFEHVKRMRYFSEIDFNTL--RTIHPPFIPQLDNEEDVGYFD 501
++ L E +K +F D+N + R + PF P ++N+ED FD
Sbjct: 321 KRHVDTRLGAGLSDAEEIKSHAFFKTTDWNLVYARQLEAPFKPNIENDEDTSLFD 375
>7295638 [T] KOG0603 Ribosomal protein S6 kinase
Length = 911
Score = 135 bits (339), Expect = 2e-31
Identities = 108/373 (28%), Positives = 161/373 (42%), Gaps = 61/373 (16%)
Query: 138 NLMGTEQITNEWQGYLTKETNILRKRRLKPKHKDFEMITXXXXXXXXXXXLARKKDTKEI 197
+L TE + + KE ++++ K FE++ L RK K+
Sbjct: 167 DLEDTEPLYETENEFELKE--VIKEGHDKADPSQFELLRVLGEGSFGKVFLVRKIIGKDA 224
Query: 198 CAXXXXXXXXXXXXEGTDHVLT--ERDILTTTRSEWLVKLLYAFQDPQSLYLAMEFVPGG 255
+ D V + ER IL ++V+L YAFQ P LYL ++F+ GG
Sbjct: 225 GTLYAMKVLKKATLKVKDRVRSTNERKILADVGHAFIVRLHYAFQTPGKLYLILDFLRGG 284
Query: 256 DFRTLLLNTKFLQAPHARFYISEMFCAVNALHQLGYTHRDLKPENFLIDSKGHIKLTDFG 315
D T L +FY++E+ A+N LH LG +RDLKPEN L+D GHI LTDFG
Sbjct: 285 DLFTRLSKEVMFTEEDVKFYLAELALAMNHLHTLGIIYRDLKPENILLDEHGHIALTDFG 344
Query: 316 LASGTVSMERIESMKIRLQEVKNLEFPEFRERSMDDRRRMYNKLREEEVRYAHSTVGSPD 375
L S + ++ K +S G+ +
Sbjct: 345 L-----SKQPLDGSK------------------------------------TYSFCGTVE 363
Query: 376 YMALEVLEAKNYDFTVDYWSLGCILFESLVGYTPFSGNSTNETYENLRNWKHVLQRPKCD 435
YMA E++ K +DF D+WS G +++E L G PF G + ET + K L P+
Sbjct: 364 YMAPEIVNRKGHDFAADWWSFGVLMYEMLTGNLPFHGQTRQETMNQILRSK--LGMPE-- 419
Query: 436 NGRYAFSDRTWELITRLI-ADPINRL----KSFEHVKRMRYFSEIDFNTL--RTIHPPFI 488
S L+ L +P NRL + +K +F+ ID+ L + + PPFI
Sbjct: 420 ----NLSPEAQSLLRALFKRNPQNRLGAGAQGILDIKAHCFFATIDWVRLERKQVRPPFI 475
Query: 489 PQLDNEEDVGYFD 501
P + + +D YFD
Sbjct: 476 PAV-SRDDAFYFD 487
>SPBC1861.09 [R] KOG0610 Putative serine/threonine protein kinase
Length = 526
Score = 134 bits (338), Expect = 3e-31
Identities = 105/363 (28%), Positives = 167/363 (45%), Gaps = 22/363 (6%)
Query: 151 GYLTKETNILRKRRLKPKHKDFEMITXXXXXXXXXXXLARKKDTKEICAXXXXXXXXXXX 210
G T N + R++ FE I L R+K + A
Sbjct: 134 GKRTYSGNSTKISRVEVTPHSFEKIRLLGQGDVGKVYLVRQKSNHRLFAMKILNKREMIK 193
Query: 211 XEGTDHVLTERDILTTTRSEWLVKLLYAFQDPQSLYLAMEFVPGGDFRTLL--LNTKFLQ 268
+ VL E++ILT ++ ++V L ++FQ LYL ME+ GG+F L L L
Sbjct: 194 RHKVNRVLAEQEILTKSKHPFIVTLYHSFQSRDYLYLCMEYCAGGEFFRALHSLPKHILP 253
Query: 269 APHARFYISEMFCAVNALHQLGYTHRDLKPENFLIDSKGHIKLTDFGLASGTVSMERIES 328
A FY +E+ A+ LH +G+ +RDLKPEN L+ GHI L+DF L S +S+ +
Sbjct: 254 EKDACFYAAEVTAALEYLHLMGFIYRDLKPENILLHQSGHIMLSDFDL-SKPISIVTHPT 312
Query: 329 MKIRLQEVKNLEFPEFRERSMDDRRRMYNKLREEEVRYAHSTVGSPDYMALEVLEAKNYD 388
+ + + E P D ++ R +S VG+ +Y+A EV+ + +
Sbjct: 313 VVLPKHSTFSQEKPAL------DTNSYFSNFR------TNSFVGTEEYIAPEVIRSCGHT 360
Query: 389 FTVDYWSLGCILFESLVGYTPFSGNSTNETYENLRNWKHVLQRPKCDNGRYAFSDRTWEL 448
VD+W+LG ++E L G TPF G + + T+ N+ + P+ +G S L
Sbjct: 361 VAVDWWTLGIFIYEILYGTTPFKGKNRHATFSNI--LYSDVSFPEY-HGAPNVSSTCKSL 417
Query: 449 ITR-LIADPINRLKSF---EHVKRMRYFSEIDFNTLRTIHPPFIPQLDNEEDVGYFDDFT 504
I R L+ D R S +K+ +F I + LR++ PP IP++++ + D
Sbjct: 418 IRRLLVKDESKRCGSVAGASDIKQHPFFRHIQWALLRSMKPPIIPKIEDGMEAVEPSDND 477
Query: 505 NEE 507
NEE
Sbjct: 478 NEE 480
>YHR205w [RT] KOG0598 Ribosomal protein S6 kinase and related proteins
Length = 824
Score = 134 bits (336), Expect = 5e-31
Identities = 110/390 (28%), Positives = 172/390 (43%), Gaps = 64/390 (16%)
Query: 161 RKRRLKPKHKDFEMITXXXXXXXXXXXLARKKDTKEICAXXXXXXXXXXXXEGTDHVLTE 220
+KR P+ DFE++ +KKDT+ I A H + E
Sbjct: 403 KKRHYGPQ--DFEVLRLLGKGTFGQVYQVKKKDTQRIYAMKVLSKKVIVKKNEIAHTIGE 460
Query: 221 RDILTTTRSE---WLVKLLYAFQDPQSLYLAMEFVPGGDFRTLLLNTKFLQAPHARFYIS 277
R+IL TT S+ ++V L ++FQ P LYL +++ GG+ L A+FYI+
Sbjct: 461 RNILVTTASKSSPFIVGLKFSFQTPTDLYLVTDYMSGGELFWHLQKEGRFSEDRAKFYIA 520
Query: 278 EMFCAVNALHQLGYTHRDLKPENFLIDSKGHIKLTDFGLASGTVSMERIESMKIRLQEVK 337
E+ A+ LH +RDLKPEN L+D+ G+I L DFGL+
Sbjct: 521 ELVLALEHLHDNDIVYRDLKPENILLDANGNIALCDFGLS-------------------- 560
Query: 338 NLEFPEFRERSMDDRRRMYNKLREEEVRYAHSTVGSPDYMALE-VLEAKNYDFTVDYWSL 396
+ + DR + G+ +Y+A E +L+ Y VD+WSL
Sbjct: 561 --------KADLKDRTNTF--------------CGTTEYLAPELLLDETGYTKMVDFWSL 598
Query: 397 GCILFESLVGYTPFSGNSTNETYENLRNWKHVLQRPKCDNGRYAFSDRTWELITRLIADP 456
G ++FE G++PF + + Y+ + K R +F L+ R +P
Sbjct: 599 GVLIFEMCCGWSPFFAENNQKMYQKIAFGKVKFPRDVLSQEGRSF---VKGLLNR---NP 652
Query: 457 INRLKSFEHVKRMR---YFSEIDFNTL--RTIHPPFIPQLDNEEDVGYFD-DFTNEEHMA 510
+RL + + + +R +F++ID+ L + I PPF P L +E D FD +FT
Sbjct: 653 KHRLGAIDDGRELRAHPFFADIDWEALKQKKIPPPFKPHLVSETDTSNFDPEFTTAS--T 710
Query: 511 RYVDVFKRQDRLTAMVDDSLSDSKLVGFTF 540
Y++ K Q +TA +K GFTF
Sbjct: 711 SYMN--KHQPMMTATPLSPAMQAKFAGFTF 738
>Hs4826948 [T] KOG0616 cAMP-dependent protein kinase catalytic subunit (PKA)
Length = 358
Score = 134 bits (336), Expect = 5e-31
Identities = 90/345 (26%), Positives = 152/345 (43%), Gaps = 58/345 (16%)
Query: 170 KDFEMITXXXXXXXXXXXLARKKDTKEICAXXXXXXXXXXXXEGTDHVLTERDILTTTRS 229
+DF+ + L ++K K A + HV E+ +L
Sbjct: 47 QDFDTLATVGTGTFGRVHLVKEKTAKHFFALKVMSIPDVIRLKQEQHVHNEKSVLKEVSH 106
Query: 230 EWLVKLLYAFQDPQSLYLAMEFVPGGDFRTLLLNTKFLQAPHARFYISEMFCAVNALHQL 289
+L++L + + D + LY+ ME+VPGG+ + L N + FY +E+ CA+ LH
Sbjct: 107 PFLIRLFWTWHDERFLYMLMEYVPGGELFSYLRNRGRFSSTTGLFYSAEIICAIEYLHSK 166
Query: 290 GYTHRDLKPENFLIDSKGHIKLTDFGLASGTVSMERIESMKIRLQEVKNLEFPEFRERSM 349
+RDLKPEN L+D GHIKLTDFG A + +
Sbjct: 167 EIVYRDLKPENILLDRDGHIKLTDFGFA-----------------------------KKL 197
Query: 350 DDRRRMYNKLREEEVRYAHSTVGSPDYMALEVLEAKNYDFTVDYWSLGCILFESLVGYTP 409
DR + G+P+Y+A EV+++K + VD+W+LG ++FE L G+ P
Sbjct: 198 VDR--------------TWTLCGTPEYLAPEVIQSKGHGRAVDWWALGILIFEMLSGFPP 243
Query: 410 FSGNSTNETYENLRNWKHVLQRPKCDNGRYAFSDRTWELITR-LIADPINRLKSFEH--- 465
F ++ Y+ + K D R+ +LI + L+ D RL + ++
Sbjct: 244 FFDDNPFGIYQK-------ILAGKIDFPRH-LDFHVKDLIKKLLVVDRTRRLGNMKNGAN 295
Query: 466 -VKRMRYFSEIDFNTL--RTIHPPFIPQLDNEEDVGYFDDFTNEE 507
VK R+F +D+ + R + PP +P++ + D F+ + +
Sbjct: 296 DVKHHRWFRSVDWEAVPQRKLKPPIVPKIAGDGDTSNFETYPEND 340
>CE28744 [RT] KOG0598 Ribosomal protein S6 kinase and related proteins
Length = 879
Score = 133 bits (335), Expect = 6e-31
Identities = 101/340 (29%), Positives = 152/340 (44%), Gaps = 56/340 (16%)
Query: 170 KDFEMITXXXXXXXXXXXLARKKDTKEICAXXXXXXXXXXXXEGTD----HVLTERDILT 225
KDFE + RK+ ++ GT+ H ER IL
Sbjct: 21 KDFERLKLVGEGGYGKVFQVRKQTGEDKGTIYAMKVITKRKVTGTEKDLRHARDERKILE 80
Query: 226 TTRSEWLVKLLYAFQDPQSLYLAMEFVPGGDFRTLLLNTKFLQAPHARFYISEMFCAVNA 285
T S +L L YAFQ + LYL +EF+ GG+ TLL +ARFY+SE+ A+
Sbjct: 81 TINSPFLCDLHYAFQTNEKLYLVLEFLHGGELYTLLERKSDWPEEYARFYLSEIILAIEH 140
Query: 286 LHQLGYTHRDLKPENFLIDSKGHIKLTDFGLASGTVSMERIESMKIRLQEVKNLEFPEFR 345
LH +RDLKP+N +++ GH+ LTDFGL K++ E K L F
Sbjct: 141 LHGHDIVYRDLKPDNVMLNLAGHVVLTDFGLC----------KYKLKKGE-KTLTF---- 185
Query: 346 ERSMDDRRRMYNKLREEEVRYAHSTVGSPDYMALEVLEAKNYDFTVDYWSLGCILFESLV 405
G+ +YMA E++ +D VD W+LG ++++ +
Sbjct: 186 -------------------------CGTHEYMAPEMIRKVGHDHAVDVWALGILMYDMFM 220
Query: 406 GYTPFSGNSTNETYENLRNWKHVLQRPKCDNGRYAFSDRTWELITRLI-ADPINRLKSFE 464
G PF+G + + +++ K L +G+ +LI R+I DP R+ +
Sbjct: 221 GGPPFTGETPADKDKSILKGKVRLPPKLSASGK--------DLIKRIIKRDPTLRI-TIP 271
Query: 465 HVKRMRYFSEIDFNTL--RTIHPPFIPQLDNEEDVGYFDD 502
+K +F EID++ L PPF P L N EDV +FD+
Sbjct: 272 DIKEHEFFEEIDWDKLMAHDFEPPFKPTLANLEDVSHFDE 311
>At3g08730 [RT] KOG0598 Ribosomal protein S6 kinase and related proteins
Length = 465
Score = 133 bits (335), Expect = 6e-31
Identities = 96/337 (28%), Positives = 150/337 (44%), Gaps = 55/337 (16%)
Query: 171 DFEMITXXXXXXXXXXXLARKKDTKEICAXXXXXXXXXXXXEGTDHVLTERDILTTTRSE 230
DFE++ RKK+T EI A +++ ERDILT
Sbjct: 133 DFEVMKVVGKGAFGKVYQVRKKETSEIYAMKVMRKDHIMEKNHAEYMKAERDILTKIDHP 192
Query: 231 WLVKLLYAFQDPQSLYLAMEFVPGGDFRTLLLNTKFLQAPHARFYISEMFCAVNALHQLG 290
++V+L Y+FQ LYL ++F+ GG L + + AR Y +E+ AV+ LH+ G
Sbjct: 193 FIVQLKYSFQTKYRLYLVLDFINGGHLFFQLYHQGLFREDLARVYTAEIVSAVSHLHEKG 252
Query: 291 YTHRDLKPENFLIDSKGHIKLTDFGLASGTVSMERIESMKIRLQEVKNLEFPEFRERSMD 350
HRDLKPEN L+D+ GH+ LTDFGLA EF E +
Sbjct: 253 IMHRDLKPENILMDTDGHVMLTDFGLAK------------------------EFEENTR- 287
Query: 351 DRRRMYNKLREEEVRYAHSTVGSPDYMALEVLEAKNYDFTVDYWSLGCILFESLVGYTPF 410
++S G+ +YMA E++ K +D D+WS+G +L+E L G PF
Sbjct: 288 ----------------SNSMCGTTEYMAPEIVRGKGHDKAADWWSVGILLYEMLTGKPPF 331
Query: 411 SGNSTNETYENLRNWKHVLQRPKCDNGRYAFSDRTWELITRLIADPINRLKS----FEHV 466
G+ + + + K ++ ++ L L +P RL S E +
Sbjct: 332 LGSK--------GKIQQKIVKDKIKLPQFLSNEAHAILKGLLQKEPERRLGSGLSGAEEI 383
Query: 467 KRMRYFSEIDFNTL--RTIHPPFIPQLDNEEDVGYFD 501
K+ ++F I++ L R + P F P++ + + FD
Sbjct: 384 KQHKWFKGINWKKLEAREVMPSFKPEVSGRQCIANFD 420
>Hs5453970 [T] KOG0694 Serine/threonine protein kinase
Length = 676
Score = 132 bits (333), Expect = 1e-30
Identities = 93/330 (28%), Positives = 150/330 (45%), Gaps = 66/330 (20%)
Query: 218 LTERDILT-TTRSEWLVKLLYAFQDPQSLYLAMEFVPGGDFRTLLLNTKFLQAPHARFYI 276
+ E+ +LT + +L L+ FQ L+ MEF+ GGD + + + A FY
Sbjct: 395 MVEKRVLTLAAENPFLTHLICTFQTKDHLFFVMEFLNGGDLMYHIQDKGRFELYRATFYA 454
Query: 277 SEMFCAVNALHQLGYTHRDLKPENFLIDSKGHIKLTDFGLASGTVSMERIESMKIRLQEV 336
+E+ C + LH G +RDLK +N L+D GHIK+ DFG+ +
Sbjct: 455 AEIMCGLQFLHSKGIIYRDLKLDNVLLDRDGHIKIADFGMCKENI--------------- 499
Query: 337 KNLEFPEFRERSMDDRRRMYNKLREEEVRYAHSTVGSPDYMALEVLEAKNYDFTVDYWSL 396
F E R A + G+PDY+A E+L+ Y F+VD+WS
Sbjct: 500 ----FGESR---------------------ASTFCGTPDYIAPEILQGLKYTFSVDWWSF 534
Query: 397 GCILFESLVGYTPFSGNSTNETYENLRNWKHVLQRPKCDNGRYA--FSDRTWELITRLI- 453
G +L+E L+G +PF G+ +E +E++R D Y + + +++ +L
Sbjct: 535 GVLLYEMLIGQSPFHGDDEDELFESIR----------VDTPHYPRWITKESKDILEKLFE 584
Query: 454 ADPINRLKSFEHVKRMRYFSEIDFNTL--RTIHPPFIPQLDNEEDVGYFD-DFTNEEHMA 510
+P RL ++K +F I++ L R + PPF P++ + D FD +F NE+
Sbjct: 585 REPTKRLGMTGNIKIHPFFKTINWTLLEKRRLEPPFRPKVKSPRDYSNFDQEFLNEKARL 644
Query: 511 RYVDVFKRQDRLTAMVDDSLSDSKLVGFTF 540
Y D + DS+ S GF+F
Sbjct: 645 SYSD---------KNLIDSMDQSAFAGFSF 665
>Hs4506737 [RT] KOG0598 Ribosomal protein S6 kinase and related proteins
Length = 525
Score = 132 bits (332), Expect = 1e-30
Identities = 96/333 (28%), Positives = 149/333 (43%), Gaps = 62/333 (18%)
Query: 214 TDHVLTERDILTTTRSEWLVKLLYAFQDPQSLYLAMEFVPGGDFRTLLLNTKFLQAPHAR 273
T H ER+IL + ++V L+YAFQ LYL +E++ GG+ L A
Sbjct: 137 TAHTKAERNILEEVKHPFIVDLIYAFQTGGKLYLILEYLSGGELFMQLEREGIFMEDTAC 196
Query: 274 FYISEMFCAVNALHQLGYTHRDLKPENFLIDSKGHIKLTDFGLASGTVSMERIESMKIRL 333
FY++E+ A+ LHQ G +RDLKPEN +++ +GH+KLTDFGL ++
Sbjct: 197 FYLAEISMALGHLHQKGIIYRDLKPENIMLNHQGHVKLTDFGLCKESI------------ 244
Query: 334 QEVKNLEFPEFRERSMDDRRRMYNKLREEEVRYAHSTVGSPDYMALEVLEAKNYDFTVDY 393
+ H+ G+ +YMA E+L ++ VD+
Sbjct: 245 ----------------------------HDGTVTHTFCGTIEYMAPEILMRSGHNRAVDW 276
Query: 394 WSLGCILFESLVGYTPFSGNSTNETYENLRNWKHVLQRPKCDNGRYAFSDRTWELITRLI 453
WSLG ++++ L G PF+G + +T + + K L R D +L+ R
Sbjct: 277 WSLGALMYDMLTGAPPFTGENRKKTIDKILKCKLNLPPYLTQEAR----DLLKKLLKRNA 332
Query: 454 ADPINR-LKSFEHVKRMRYFSEIDFNTL--RTIHPPFIPQLDNEEDVGYFDDFTNEEHMA 510
A + V+ +F I++ L R + PPF P L +EEDV FD
Sbjct: 333 ASRLGAGPGDAGEVQAHPFFRHINWEELLARKVEPPFKPLLQSEEDVSQFD--------- 383
Query: 511 RYVDVFKRQDRLTAMVDDSLSDSK---LVGFTF 540
F RQ + + D +LS+S +GFT+
Sbjct: 384 ---SKFTRQTPVDSPDDSTLSESANQVFLGFTY 413
>Hs14735945 [T] KOG0694 Serine/threonine protein kinase
Length = 676
Score = 132 bits (332), Expect = 1e-30
Identities = 93/330 (28%), Positives = 150/330 (45%), Gaps = 66/330 (20%)
Query: 218 LTERDILT-TTRSEWLVKLLYAFQDPQSLYLAMEFVPGGDFRTLLLNTKFLQAPHARFYI 276
+ E+ +LT + +L L+ FQ L+ MEF+ GGD + + + A FY
Sbjct: 395 MVEKRVLTLAAENPFLTHLICTFQTKDHLFFVMEFLNGGDLMYHIQDKGRFELYRATFYA 454
Query: 277 SEMFCAVNALHQLGYTHRDLKPENFLIDSKGHIKLTDFGLASGTVSMERIESMKIRLQEV 336
+E+ C + LH G +RDLK +N L+D GHIK+ DFG+ +
Sbjct: 455 AEIMCGLQFLHSKGIIYRDLKLDNVLLDRDGHIKIADFGMCKENI--------------- 499
Query: 337 KNLEFPEFRERSMDDRRRMYNKLREEEVRYAHSTVGSPDYMALEVLEAKNYDFTVDYWSL 396
F E R A + G+PDY+A E+L+ Y F+VD+WS
Sbjct: 500 ----FGESR---------------------ASTFCGTPDYIAPEILQGLKYTFSVDWWSF 534
Query: 397 GCILFESLVGYTPFSGNSTNETYENLRNWKHVLQRPKCDNGRYA--FSDRTWELITRLI- 453
G +L+E L+G +PF G+ +E +E++R D Y + + +++ +L
Sbjct: 535 GVLLYEMLIGQSPFHGDDEDELFESIR----------VDTPHYPRWITKESKDILEKLFE 584
Query: 454 ADPINRLKSFEHVKRMRYFSEIDFNTL--RTIHPPFIPQLDNEEDVGYFD-DFTNEEHMA 510
+P RL ++K +F I++ L R + PPF P++ + D FD +F NE+
Sbjct: 585 REPTKRLGVTGNIKIHPFFKTINWTLLEKRRLEPPFRPKVKSPRDYSNFDQEFLNEKARL 644
Query: 511 RYVDVFKRQDRLTAMVDDSLSDSKLVGFTF 540
Y D + DS+ S GF+F
Sbjct: 645 SYSD---------KNLIDSMDQSAFAGFSF 665
>7303111 [T] KOG0695 Serine/threonine protein kinase
Length = 690
Score = 132 bits (332), Expect = 1e-30
Identities = 107/385 (27%), Positives = 172/385 (43%), Gaps = 68/385 (17%)
Query: 171 DFEMITXXXXXXXXXXXLARKKDTKEICAXXXXXXXXXXXXEGTDHVLTERDILTTTRSE 230
DFE+I + + T+ I A E D V TE+ + T +
Sbjct: 260 DFELIRVIGRGSYAKVLMVELRRTRRIYAMKVIKKALVTDDEDIDWVQTEKHVFETASNH 319
Query: 231 -WLVKLLYAFQDPQSLYLAMEFVPGGDFRTLLLNTKFLQAPHARFYISEMFCAVNALHQL 289
+LV L FQ P L+ +EFV GGD + + L HARFY +E+ A+N LH+
Sbjct: 320 PFLVGLHSCFQTPSRLFFVIEFVRGGDLMYHMQRQRRLPEEHARFYAAEISLALNFLHEK 379
Query: 290 GYTHRDLKPENFLIDSKGHIKLTDFGLASGTVSMERIESMKIRLQEVKNLEFPEFRERSM 349
G +RDLK +N L+D +GHIKLTD+G+
Sbjct: 380 GIIYRDLKLDNVLLDHEGHIKLTDYGMC-------------------------------- 407
Query: 350 DDRRRMYNKLREEEVRYAHST---VGSPDYMALEVLEAKNYDFTVDYWSLGCILFESLVG 406
+E +R +T G+P+Y+A E+L ++Y F+VD+W+LG +L+E L G
Sbjct: 408 -----------KEGIRPGDTTSTFCGTPNYIAPEILRGEDYGFSVDWWALGVLLYEMLAG 456
Query: 407 YTPF--SGNSTNETYENLRNWKHVLQRPKCDNGRYAFSDRTWELITRLI-ADPINRL--- 460
+PF +G S N +N ++ + K + S R ++ + +P +RL
Sbjct: 457 RSPFDLAGASENPD-QNTEDYLFQVILEKTIRIPRSLSVRAASVLKGFLNKNPADRLGCH 515
Query: 461 --KSFEHVKRMRYFSEIDFNTL--RTIHPPFIPQLDNEEDVGYF-DDFTNEEHMARYVDV 515
+F + +F +D+ L + + PPF P+LD++ D+ F +FT E V +
Sbjct: 516 RESAFMDIVSHPFFKNMDWELLERKQVTPPFKPRLDSDRDLANFPPEFTGEA-----VQL 570
Query: 516 FKRQDRLTAMVDDSLSDSKLVGFTF 540
D V D++ S+ GF +
Sbjct: 571 TPDDDH----VIDNIDQSEFEGFEY 591
>SPAC1B9.02c [RT] KOG0598 Ribosomal protein S6 kinase and related proteins
Length = 696
Score = 132 bits (331), Expect = 2e-30
Identities = 109/411 (26%), Positives = 181/411 (43%), Gaps = 59/411 (14%)
Query: 145 ITNEWQGYLTKETNILRKRRLKPKHKDFEMITXXXXXXXXXXXLARKKDTKEICAXXXXX 204
+T +G + ET ++ +DF + L RK DT I A
Sbjct: 275 LTKSLEGEIKVETIYEHIEHVRYGPEDFTALRLIGKGTFGQVYLVRKNDTNRIYAMKKIS 334
Query: 205 XXXXXXXEGTDHVLTERDILTTT---RSEWLVKLLYAFQDPQSLYLAMEFVPGGDFRTLL 261
+ H L ER+IL T S ++V L ++FQ LYL +++ GG+ L
Sbjct: 335 KKLIVRKKEVTHTLGERNILVRTSLDESPFIVGLKFSFQTASDLYLITDYMSGGELFWHL 394
Query: 262 LNTKFLQAPHARFYISEMFCAVNALHQLGYTHRDLKPENFLIDSKGHIKLTDFGLASGTV 321
+ A+FYI+E+ A+ LH+ +RDLKPEN L+D+ GHI L DFGL+ +
Sbjct: 395 QHEGRFPEQRAKFYIAELVLALEHLHKHDIIYRDLKPENILLDADGHIALCDFGLSKANL 454
Query: 322 SMERIESMKIRLQEVKNLEFPEFRERSMDDRRRMYNKLREEEVRYAHSTVGSPDYMALEV 381
S ++ G+ +Y+A EV
Sbjct: 455 SANAT----------------------------------------TNTFCGTTEYLAPEV 474
Query: 382 -LEAKNYDFTVDYWSLGCILFESLVGYTPFSGNSTNETYENLRNWKHVLQRPKCDNGRYA 440
LE K Y VD+WSLG ++FE G++PF + Y N+ K ++ PK G +
Sbjct: 475 LLEDKGYTKQVDFWSLGVLVFEMCCGWSPFYAPDVQQMYRNIAFGK--VRFPK---GVLS 529
Query: 441 FSDRTW--ELITRLIADPINRLKSFEHVKRMRYFSEIDFNTL--RTIHPPFIPQLDNEED 496
R++ L+ R + + +K +F++I+++ L + + PPF P + N+ D
Sbjct: 530 SEGRSFVRGLLNRNPNHRLGAVADTTELKEHPFFADINWDLLSKKKVQPPFKPNVQNDLD 589
Query: 497 VGYFD-DFTNEEHMARYVDVFKRQDRLTAM--VDDSLSDSKLVGFTFRHRN 544
V FD +FTN + +++ D A + +++ D + GFTF +++
Sbjct: 590 VSNFDKEFTNTN--VKNINIVSNVDPANASTPLSNTIQD-RFRGFTFVNKS 637
>CE15473 [T] KOG0616 cAMP-dependent protein kinase catalytic subunit (PKA)
Length = 359
Score = 131 bits (330), Expect = 2e-30
Identities = 89/343 (25%), Positives = 149/343 (42%), Gaps = 58/343 (16%)
Query: 171 DFEMITXXXXXXXXXXXLARKKDTKEICAXXXXXXXXXXXXEGTDHVLTERDILTTTRSE 230
DF+ I L + K + A + +H L E+ IL
Sbjct: 51 DFDRIKTLGTGSFGRVMLVKHKQSGNYYAMKILDKQKVVKLKQVEHTLNEKRILQAIDFP 110
Query: 231 WLVKLLYAFQDPQSLYLAMEFVPGGDFRTLLLNTKFLQAPHARFYISEMFCAVNALHQLG 290
+LV + ++F+D +LY+ +EF+ GG+ + L PH+RFY +++ A LH L
Sbjct: 111 FLVNMTFSFKDNSNLYMVLEFISGGEMFSHLRRIGRFSEPHSRFYAAQIVLAFEYLHSLD 170
Query: 291 YTHRDLKPENFLIDSKGHIKLTDFGLASGTVSMERIESMKIRLQEVKNLEFPEFRERSMD 350
+RDLKPEN LIDS G++K+TDFG A + VK +
Sbjct: 171 LIYRDLKPENLLIDSTGYLKITDFGFA----------------KRVKGRTW--------- 205
Query: 351 DRRRMYNKLREEEVRYAHSTVGSPDYMALEVLEAKNYDFTVDYWSLGCILFESLVGYTPF 410
+ G+P+Y+A E++ +K Y+ VD+W+LG +++E GY PF
Sbjct: 206 ------------------TLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPF 247
Query: 411 SGNSTNETYENLRNWKHVLQRPKCDNGRYAFSDRTWELITRLIADPI-----NRLKSFEH 465
+ + YE + + K ++ P FS+ +L+ L+ + N
Sbjct: 248 FADQPIQIYEKIVSGK--VKFPS------HFSNELKDLLKNLLQVDLTKRYGNLKNGVAD 299
Query: 466 VKRMRYFSEIDFNTL--RTIHPPFIPQLDNEEDVGYFDDFTNE 506
+K ++F D+ + + I PF+P+ D FDD+ E
Sbjct: 300 IKNHKWFGSTDWIAIYQKKIEAPFLPKCRGPGDASNFDDYEEE 342
>At3g20830 [R] KOG0610 Putative serine/threonine protein kinase
Length = 408
Score = 131 bits (330), Expect = 2e-30
Identities = 90/301 (29%), Positives = 147/301 (47%), Gaps = 34/301 (11%)
Query: 226 TTRSEWLVKLLYAFQDPQSLYLAMEFVPGGDFRTLL--LNTKFLQAPHARFYISEMFCAV 283
+ ++ +L +LL +F+ P+ A+ + GGD LL N + RFY++E+ CA+
Sbjct: 81 SNQNPFLPRLLASFESPEYFAWAVPYCSGGDLNVLLHRQNDGVFSSSVIRFYVAEIVCAL 140
Query: 284 NALHQLGYTHRDLKPENFLIDSKGHIKLTDFGLASGTVSMERIE----SMKIRLQEVKNL 339
LH +G +RDLKPEN LI GH+ LTDF L+ R ++ + K+
Sbjct: 141 EHLHTMGIAYRDLKPENILIQQSGHVTLTDFDLSRSLKKPLRPHFYQPDPELIIDRKKSR 200
Query: 340 EFPEFRERSMDDRRRMYNKLREEEV-------------RYAHSTVGSPDYMALEVLEAKN 386
F + + + K R V ++S VG+ +Y++ EV+
Sbjct: 201 SFSRLISPTAEKNKTGLKKTRSARVNPINRRKTSFSSGERSNSFVGTDEYVSPEVIRGDG 260
Query: 387 YDFTVDYWSLGCILFESLVGYTPFSGNSTNETYENLRNWKHVLQRPKCDNGRYAFSDRTW 446
+DF VD+W+LG + +E + G TPF G S ET+ N+ +++ P+ +D
Sbjct: 261 HDFAVDWWALGVLTYEMMYGETPFKGKSKKETFRNV-----LMKEPEFAGKPNDLTD--- 312
Query: 447 ELITR-LIADPINRL---KSFEHVKRMRYFSEIDFNTL-RTIHPPFIPQLDNEE-DVGYF 500
LI R L+ DP RL + +K + +F+ + ++ L + PPFIP D+ E VG F
Sbjct: 313 -LIRRLLVKDPNRRLGCHRGAAEIKELAFFAGVRWDLLTEVLRPPFIPLRDDGELTVGGF 371
Query: 501 D 501
D
Sbjct: 372 D 372
>YPL203w [T] KOG0616 cAMP-dependent protein kinase catalytic subunit (PKA)
Length = 380
Score = 130 bits (326), Expect = 7e-30
Identities = 88/301 (29%), Positives = 148/301 (48%), Gaps = 59/301 (19%)
Query: 215 DHVLTERDILTTTRSEWLVKLLYAFQDPQSLYLAMEFVPGGDFRTLLLNTKFLQAPHARF 274
+H ER +L +L+++ FQD +++++ M+++ GG+ +LL ++ P A+F
Sbjct: 113 EHTNDERRMLKLVEHPFLIRMWGTFQDARNIFMVMDYIEGGELFSLLRKSQRFPNPVAKF 172
Query: 275 YISEMFCAVNALHQLGYTHRDLKPENFLIDSKGHIKLTDFGLASGTVSMERIESMKIRLQ 334
Y +E+ A+ LH +RDLKPEN L+D GHIK+TDFG A +
Sbjct: 173 YAAEVILALEYLHAHNIIYRDLKPENILLDRNGHIKITDFGFA----------------K 216
Query: 335 EVKNLEFPEFRERSMDDRRRMYNKLREEEVRYAHSTVGSPDYMALEVLEAKNYDFTVDYW 394
EV+ + + + G+PDY+A EV+ K Y+ +VD+W
Sbjct: 217 EVQTVTW---------------------------TLCGTPDYIAPEVITTKPYNKSVDWW 249
Query: 395 SLGCILFESLVGYTPFSGNSTNETYENLRNWKHVLQRPKCDNGRYAFSDRTWELITRLI- 453
SLG +++E L GYTPF + +TYE + K V+ P F +L+++LI
Sbjct: 250 SLGVLIYEMLAGYTPFYDTTPMKTYEKILQGK-VVYPP-------YFHPDVVDLLSKLIT 301
Query: 454 ADPINRLKSFE----HVKRMRYFSEIDFNTL--RTIHPPFIPQLDNE-EDVGYFDDFTNE 506
AD R+ + + +K +FSE+ + L + I P+ P + + D FD + E
Sbjct: 302 ADLTRRIGNLQSGSRDIKAHPWFSEVVWERLLAKDIETPYEPPITSGIGDTSLFDQYPEE 361
Query: 507 E 507
+
Sbjct: 362 Q 362
>Hs4885549 [T] KOG0690 Serine/threonine protein kinase
Length = 479
Score = 129 bits (324), Expect = 1e-29
Identities = 98/377 (25%), Positives = 155/377 (40%), Gaps = 57/377 (15%)
Query: 132 EEQRRSNLMGTEQITNEWQGYLTKETNILRKRRLKPKHKDFEMITXXXXXXXXXXXLARK 191
+E+ R N T QI N + + T +++ + DF+ + L R+
Sbjct: 112 QEEERMNCSPTSQIDNIGEEEMDASTTHHKRKTMN----DFDYLKLLGKGTFGKVILVRE 167
Query: 192 KDTKEICAXXXXXXXXXXXXEGTDHVLTERDILTTTRSEWLVKLLYAFQDPQSLYLAMEF 251
K + + A + H LTE +L TR +L L Y+FQ L ME+
Sbjct: 168 KASGKYYAMKILKKEVIIAKDEVAHTLTESRVLKNTRHPFLTSLKYSFQTKDRLCFVMEY 227
Query: 252 VPGGDFRTLLLNTKFLQAPHARFYISEMFCAVNALHQLGYTHRDLKPENFLIDSKGHIKL 311
V GG+ L + RFY +E+ A++ LH +RDLK EN ++D GHIK+
Sbjct: 228 VNGGELFFHLSRERVFSEDRTRFYGAEIVSALDYLHSGKIVYRDLKLENLMLDKDGHIKI 287
Query: 312 TDFGLASGTVSMERIESMKIRLQEVKNLEFPEFRERSMDDRRRMYNKLREEEVRYAHSTV 371
TDFGL ++ + +
Sbjct: 288 TDFGLCKEGIT----------------------------------------DAATMKTFC 307
Query: 372 GSPDYMALEVLEAKNYDFTVDYWSLGCILFESLVGYTPFSGNSTNETYENLRNWKHVLQR 431
G+P+Y+A EVLE +Y VD+W LG +++E + G PF + +E ++
Sbjct: 308 GTPEYLAPEVLEDNDYGRAVDWWGLGVVMYEMMCGRLPFYNQDHEKLFE-------LILM 360
Query: 432 PKCDNGRYAFSDRTWELITRLIADPINRL----KSFEHVKRMRYFSEIDFNTL--RTIHP 485
R SD L LI DP RL + + R +FS +++ + + + P
Sbjct: 361 EDIKFPRTLSSDAKSLLSGLLIKDPNKRLGGGPDDAKEIMRHSFFSGVNWQDVYDKKLVP 420
Query: 486 PFIPQLDNEEDVGYFDD 502
PF PQ+ +E D YFD+
Sbjct: 421 PFKPQVTSETDTRYFDE 437
>CE05274 [T] KOG0690 Serine/threonine protein kinase
Length = 546
Score = 129 bits (323), Expect = 2e-29
Identities = 99/360 (27%), Positives = 153/360 (42%), Gaps = 67/360 (18%)
Query: 163 RRLKPKHKDFEMITXXXXXXXXXXXLARKKDTKEICAXXXXXXXXXXXXEGTDHVLTERD 222
+R K +DF+ + L ++K T+++ A E H LTE
Sbjct: 184 KRDKITMEDFDFLKVLGKGTFGKVILCKEKRTQKLYAIKILKKDVIIAREEVAHTLTENR 243
Query: 223 ILTTTRSEWLVKLLYAFQDPQSLYLAMEFVPGGDF-----RTLLLNTKFLQAPHARFYIS 277
+L + +L +L Y+FQ L MEF GGD R + +N + P ARFY S
Sbjct: 244 VLQRCKHPFLTELKYSFQTNDRLCFVMEFAIGGDLYYHLNREVQMNKEGFSEPRARFYGS 303
Query: 278 EMFCAVNALHQLGYTHRDLKPENFLIDSKGHIKLTDFGLASGTVSMERIESMKIRLQEVK 337
E+ A+ LH +RDLK EN L+D GHIK+ DFGL
Sbjct: 304 EIVLALGYLHANSIVYRDLKLENLLLDKDGHIKIADFGLC-------------------- 343
Query: 338 NLEFPEFRERSMDDRRRMYNKLREEEVRYAHST---VGSPDYMALEVLEAKNYDFTVDYW 394
+EE+ + T G+P+Y+A EVL+ +Y VD+W
Sbjct: 344 -----------------------KEEISFGDKTSTFCGTPEYLAPEVLDDHDYGRCVDWW 380
Query: 395 SLGCILFESLVGYTPFSGNSTNETYENLRNWKHVLQRPKCDNGRYAFSDRTWELIT-RLI 453
+G +++E + G PF N+ +E + L+ P S L+T L+
Sbjct: 381 GVGVVMYEMMCGRLPFYSKDHNKLFELIMAGD--LRFPS------KLSQEARTLLTGLLV 432
Query: 454 ADPINRL----KSFEHVKRMRYFSEIDFNTL--RTIHPPFIPQLDNEEDVGYFD-DFTNE 506
DP RL + + R +F +D+ + I PP+ P + +E D YFD +FT++
Sbjct: 433 KDPTQRLGGGPEDALEICRADFFRTVDWEATYRKEIEPPYKPNVQSETDTSYFDNEFTSQ 492
>Hs4506739 [RT] KOG0598 Ribosomal protein S6 kinase and related proteins
Length = 495
Score = 128 bits (321), Expect = 3e-29
Identities = 96/337 (28%), Positives = 152/337 (44%), Gaps = 70/337 (20%)
Query: 214 TDHVLTERDILTTTRSEWLVKLLYAFQDPQSLYLAMEFVPGGDFRTLLLNTKFLQAPHAR 273
T H ER+IL + + ++V+L YAFQ LYL +E + GG+ T L A
Sbjct: 126 TAHTRAERNILESVKHPFIVELAYAFQTGGKLYLILECLSGGELFTHLEREGIFLEDTAC 185
Query: 274 FYISEMFCAVNALHQLGYTHRDLKPENFLIDSKGHIKLTDFGLASGTVSMERIESMKIRL 333
FY++E+ A+ LH G +RDLKPEN ++ S+GHIKLTDFGL ++
Sbjct: 186 FYLAEITLALGHLHSQGIIYRDLKPENIMLSSQGHIKLTDFGLCKESI------------ 233
Query: 334 QEVKNLEFPEFRERSMDDRRRMYNKLREEEVRYAHSTVGSPDYMALEVLEAKNYDFTVDY 393
E H+ G+ +YMA E+L ++ VD+
Sbjct: 234 ----------------------------HEGAVTHTFCGTIEYMAPEILVRSGHNRAVDW 265
Query: 394 WSLGCILFESLVGYTPFSGNSTNETYENLRNWKHVLQRPKCDNGRYAFSDRTWELITRLI 453
WSLG ++++ L G PF+ + +T + + K L + R +L+ + +
Sbjct: 266 WSLGALMYDMLTGSPPFTAENRKKTMDKIIRGKLALPPYLTPDAR--------DLVKKFL 317
Query: 454 -ADPINRL----KSFEHVKRMRYFSEIDFNTLRT--IHPPFIPQLDNEEDVGYFDDFTNE 506
+P R+ V+R +F ++++ L + PPF P L +EEDV FD
Sbjct: 318 KRNPSQRIGGGPGDAADVQRHPFFRHMNWDDLLAWRVDPPFRPCLQSEEDVSQFD----- 372
Query: 507 EHMARYVDVFKRQDRLTAMVDDSLSDS---KLVGFTF 540
F RQ + + D +LS+S +GFT+
Sbjct: 373 -------TRFTRQTPVDSPDDTALSESANQAFLGFTY 402
>CE15612 [T] KOG0690 Serine/threonine protein kinase
Length = 541
Score = 127 bits (319), Expect = 5e-29
Identities = 94/355 (26%), Positives = 152/355 (42%), Gaps = 62/355 (17%)
Query: 163 RRLKPKHKDFEMITXXXXXXXXXXXLARKKDTKEICAXXXXXXXXXXXXEGTDHVLTERD 222
+R K +DF+ + L ++K T+++ A E H LTE
Sbjct: 184 KRDKITMEDFDFLKVLGKGTFGKVILCKEKRTQKLYAIKILKKDVIIAREEVAHTLTENR 243
Query: 223 ILTTTRSEWLVKLLYAFQDPQSLYLAMEFVPGGDFRTLLLNTKFLQAPHARFYISEMFCA 282
+L + +L +L Y+FQ+ L M+F GG+ T + P ARFY +E+ A
Sbjct: 244 VLQRCKHPFLTELKYSFQEQHYLCFVMQFANGGELFTHVRKCGTFSEPRARFYGAEIVLA 303
Query: 283 VNALHQLGYTHRDLKPENFLIDSKGHIKLTDFGLASGTVSMERIESMKIRLQEVKNLEFP 342
+ LH+ +RD+K EN L+D GHIK+ DFGL
Sbjct: 304 LGYLHRCDIVYRDMKLENLLLDKDGHIKIADFGLC------------------------- 338
Query: 343 EFRERSMDDRRRMYNKLREEEVRYAHST---VGSPDYMALEVLEAKNYDFTVDYWSLGCI 399
+EE+ + T G+P+Y+A EVL+ +Y VD+W +G +
Sbjct: 339 ------------------KEEISFGDKTSTFCGTPEYLAPEVLDDHDYGRCVDWWGVGVV 380
Query: 400 LFESLVGYTPFSGNSTNETYENLRNWKHVLQRPKCDNGRYAFSDRTWELIT-RLIADPIN 458
++E + G PF N+ +E + L+ P S L+T L+ DP
Sbjct: 381 MYEMMCGRLPFYSKDHNKLFELIMAGD--LRFPS------KLSQEARTLLTGLLVKDPTQ 432
Query: 459 RL----KSFEHVKRMRYFSEIDFNTL--RTIHPPFIPQLDNEEDVGYFD-DFTNE 506
RL + + R +F +D+ + I PP+ P + +E D YFD +FT++
Sbjct: 433 RLGGGPEDALEICRADFFRTVDWEATYRKEIEPPYKPNVQSETDTSYFDNEFTSQ 487
>7295426 [RT] KOG0598 Ribosomal protein S6 kinase and related proteins
Length = 490
Score = 127 bits (319), Expect = 5e-29
Identities = 99/337 (29%), Positives = 150/337 (44%), Gaps = 70/337 (20%)
Query: 214 TDHVLTERDILTTTRSEWLVKLLYAFQDPQSLYLAMEFVPGGDFRTLLLNTKFLQAPHAR 273
T H ER+IL + ++V+L+YAFQ LYL +E++ GG+ L
Sbjct: 123 TAHTRAERNILEAVKHPFIVELVYAFQTDGKLYLILEYLSGGELFMHLEREGIFLEDTTC 182
Query: 274 FYISEMFCAVNALHQLGYTHRDLKPENFLIDSKGHIKLTDFGLASGTVSMERIESMKIRL 333
FY+SE+ A+ LH+LG +RDLKPEN L+D++GH+KLTDFGL
Sbjct: 183 FYLSEIILALGHLHKLGIIYRDLKPENILLDAQGHVKLTDFGLC---------------- 226
Query: 334 QEVKNLEFPEFRERSMDDRRRMYNKLREEEVRYAHSTVGSPDYMALEVLEAKNYDFTVDY 393
K +E H+ G+ +YMA E+L + VD+
Sbjct: 227 ------------------------KEHIQEGIVTHTFCGTIEYMAPEILTRSGHGKAVDW 262
Query: 394 WSLGCILFESLVGYTPFSGNSTNETYENLRNWKHVLQRPKCDNGRYAFSDRTWELITRLI 453
WSLG ++F+ L G PF+ + +T E + K L R +L+ RL+
Sbjct: 263 WSLGALMFDMLTGVPPFTAENRKKTIETILKAKLNLPAYLTPEAR--------DLVRRLM 314
Query: 454 -ADPINRLKSFEH----VKRMRYFSEIDFNTL--RTIHPPFIPQLDNEEDVGYFDDFTNE 506
RL S V+ +F ++++ + R + PP P L +E+DV FD
Sbjct: 315 KRQEPQRLGSGPEDAAAVQIHPFFKHVNWDDVLARRLEPPIKPLLRSEDDVSQFD----- 369
Query: 507 EHMARYVDVFKRQDRLTAMVDDSLSDSK---LVGFTF 540
F RQ + + D +LS+S GFT+
Sbjct: 370 -------TRFTRQIPVDSPDDTTLSESANLIFQGFTY 399
>Hs4885563 [T] KOG0694 Serine/threonine protein kinase
Length = 737
Score = 126 bits (316), Expect = 1e-28
Identities = 97/357 (27%), Positives = 153/357 (42%), Gaps = 63/357 (17%)
Query: 171 DFEMITXXXXXXXXXXXLARKKDTKEICAXXXXXXXXXXXXEGTDHVLTERDILTTTRSE 230
+F I LA K E+ A + D +TE+ IL R
Sbjct: 407 EFNFIKVLGKGSFGKVMLAELKGKDEVYAVKVLKKDVILQDDDVDCTMTEKRILALARKH 466
Query: 231 -WLVKLLYAFQDPQSLYLAMEFVPGGDFRTLLLNTKFLQAPHARFYISEMFCAVNALHQL 289
+L +L FQ L+ ME+V GGD + ++ P +RFY +E+ A+ LHQ
Sbjct: 467 PYLTQLYCCFQTKDRLFFVMEYVNGGDLMFQIQRSRKFDEPRSRFYAAEVTSALMFLHQH 526
Query: 290 GYTHRDLKPENFLIDSKGHIKLTDFGLASGTVSMERIESMKIRLQEVKNLEFPEFRERSM 349
G +RDLK +N L+D++GH KL DFG+ + L V F
Sbjct: 527 GVIYRDLKLDNILLDAEGHCKLADFGMCKEGI-----------LNGVTTTTF-------- 567
Query: 350 DDRRRMYNKLREEEVRYAHSTVGSPDYMALEVLEAKNYDFTVDYWSLGCILFESLVGYTP 409
G+PDY+A E+L+ Y +VD+W+LG +++E + G P
Sbjct: 568 ---------------------CGTPDYIAPEILQELEYGPSVDWWALGVLMYEMMAGQPP 606
Query: 410 FSGNSTNETYENLRNWKHVLQRPKCDNGRYAF---SDRTWELITRLIADPINRL------ 460
F ++ ++ +E++ + D+ Y + L + +P RL
Sbjct: 607 FEADNEDDLFESILH----------DDVLYPVWLSKEAVSILKAFMTKNPHKRLGCVASQ 656
Query: 461 KSFEHVKRMRYFSEIDFNTL--RTIHPPFIPQLDNEEDVGYFD-DFTNEEHMARYVD 514
+ +K+ +F EID+ L + I PPF P++ + DV FD DFT EE + VD
Sbjct: 657 NGEDAIKQHPFFKEIDWVLLEQKKIKPPFKPRIKTKRDVNNFDQDFTREEPVLTLVD 713
>CE18646 [T] KOG0690 Serine/threonine protein kinase
Length = 528
Score = 126 bits (316), Expect = 1e-28
Identities = 94/350 (26%), Positives = 145/350 (40%), Gaps = 70/350 (20%)
Query: 171 DFEMITXXXXXXXXXXXLARKKDTKEICAXXXXXXXXXXXXEGTDHVLTERDILTTTRSE 230
DF+ + L R+K + ++ A H LTE +L
Sbjct: 179 DFDFLKVLGQGTFGKVILCREKSSDKLYAIKIIRKEMVVDRSEVAHTLTENRVLYACVHP 238
Query: 231 WLVKLLYAFQDPQSLYLAMEFVPGGDFRTLLLNTKFLQAPHARFYISEMFCAVNALHQLG 290
+L L Y+FQ + MEF GG+ T L K RFY SE+ A+ LH
Sbjct: 239 FLTLLKYSFQAQYHICFVMEFANGGELFTHLQRCKTFSEARTRFYGSEIILALGYLHHRN 298
Query: 291 YTHRDLKPENFLIDSKGHIKLTDFGLASGTVSMERIESMKIRLQEVKNLEFPEFRERSMD 350
+RD+K EN L+D GHIK+TDFGL
Sbjct: 299 IVYRDMKLENLLLDRDGHIKITDFGLC--------------------------------- 325
Query: 351 DRRRMYNKLREEEVRYAHST---VGSPDYMALEVLEAKNYDFTVDYWSLGCILFESLVGY 407
+EE++Y T G+P+Y+A EV+E +YD +VD+W +G +++E + G
Sbjct: 326 ----------KEEIKYGDKTSTFCGTPEYLAPEVIEDIDYDRSVDWWGVGVVMYEMMCGR 375
Query: 408 TPFSGNSTNETYENLRNWKHVLQRPKCDNGRYAFSDRTWELITRLIADPINRLKS----- 462
PFS + +E + CD F +R L++ + R+ +
Sbjct: 376 LPFSAKENGKLFELITT---------CD---LKFPNRLSPEAVTLLSGLLERVPAKRLGA 423
Query: 463 ----FEHVKRMRYFSEIDFN-TLR-TIHPPFIPQLDNEEDVGYFD-DFTN 505
V R +F ++D+ TLR + PPF P + +E D +FD +FT+
Sbjct: 424 GPDDAREVSRAEFFKDVDWEATLRKEVEPPFKPNVMSETDTSFFDREFTS 473
>Hs20535816 [T] KOG0695 Serine/threonine protein kinase
Length = 592
Score = 125 bits (314), Expect = 2e-28
Identities = 100/349 (28%), Positives = 155/349 (43%), Gaps = 55/349 (15%)
Query: 170 KDFEMITXXXXXXXXXXXLARKKDTKEICAXXXXXXXXXXXXEGTDHVLTERDILTTTRS 229
+DF++I L R K +I A E D V TE+ + S
Sbjct: 250 QDFDLIRVIGRGSYAKVLLVRLKKNDQIYAMKVVKKELVHDDEDIDWVQTEKHVFEQASS 309
Query: 230 E-WLVKLLYAFQDPQSLYLAMEFVPGGDFRTLLLNTKFLQAPHARFYISEMFCAVNALHQ 288
+LV L FQ L+L +E+V GGD + + L HARFY +E+ A+N LH+
Sbjct: 310 NPFLVGLHSCFQTTSRLFLVIEYVNGGDLMFHMQRQRKLPEEHARFYAAEICIALNFLHE 369
Query: 289 LGYTHRDLKPENFLIDSKGHIKLTDFGLASGTVSMERIESMKIRLQEVKNLEFPEFRERS 348
G +RDLK +N L+D+ GHIKLTD+G+ + S
Sbjct: 370 RGIIYRDLKLDNVLLDADGHIKLTDYGMCKEGLGPGDTTS-------------------- 409
Query: 349 MDDRRRMYNKLREEEVRYAHSTVGSPDYMALEVLEAKNYDFTVDYWSLGCILFESLVGYT 408
+ G+P+Y+A E+L + Y F+VD+W+LG ++FE + G +
Sbjct: 410 --------------------TFCGTPNYIAPEILRGEEYGFSVDWWALGVLMFEMMAGRS 449
Query: 409 PF---SGNSTNETYENLRNWKHVLQRPKCDNGRYAFSDRTWELITRLIADPINRL----- 460
PF + N T + L ++ +L++P R+ + L L DP RL
Sbjct: 450 PFDIITDNPDMNTEDYL--FQVILEKP-IRIPRFLSVKASHVLKGFLNKDPKERLGCRPQ 506
Query: 461 KSFEHVKRMRYFSEIDFNTL--RTIHPPFIPQLDNEEDVGYFD-DFTNE 506
F +K +F ID++ L + PPF PQ+ ++ + FD FT+E
Sbjct: 507 TGFSDIKSHAFFRSIDWDLLEKKQALPPFQPQITDDYGLDNFDTQFTSE 555
>Hs10864650 [T] KOG0695 Serine/threonine protein kinase
Length = 592
Score = 125 bits (314), Expect = 2e-28
Identities = 100/349 (28%), Positives = 155/349 (43%), Gaps = 55/349 (15%)
Query: 170 KDFEMITXXXXXXXXXXXLARKKDTKEICAXXXXXXXXXXXXEGTDHVLTERDILTTTRS 229
+DF++I L R K +I A E D V TE+ + S
Sbjct: 250 QDFDLIRVIGRGSYAKVLLVRLKKNDQIYAMKVVKKELVHDDEDIDWVQTEKHVFEQASS 309
Query: 230 E-WLVKLLYAFQDPQSLYLAMEFVPGGDFRTLLLNTKFLQAPHARFYISEMFCAVNALHQ 288
+LV L FQ L+L +E+V GGD + + L HARFY +E+ A+N LH+
Sbjct: 310 NPFLVGLHSCFQTTSRLFLVIEYVNGGDLMFHMQRQRKLPEEHARFYAAEICIALNFLHE 369
Query: 289 LGYTHRDLKPENFLIDSKGHIKLTDFGLASGTVSMERIESMKIRLQEVKNLEFPEFRERS 348
G +RDLK +N L+D+ GHIKLTD+G+ + S
Sbjct: 370 RGIIYRDLKLDNVLLDADGHIKLTDYGMCKEGLGPGDTTS-------------------- 409
Query: 349 MDDRRRMYNKLREEEVRYAHSTVGSPDYMALEVLEAKNYDFTVDYWSLGCILFESLVGYT 408
+ G+P+Y+A E+L + Y F+VD+W+LG ++FE + G +
Sbjct: 410 --------------------TFCGTPNYIAPEILRGEEYGFSVDWWALGVLMFEMMAGRS 449
Query: 409 PF---SGNSTNETYENLRNWKHVLQRPKCDNGRYAFSDRTWELITRLIADPINRL----- 460
PF + N T + L ++ +L++P R+ + L L DP RL
Sbjct: 450 PFDIITDNPDMNTEDYL--FQVILEKP-IRIPRFLSVKASHVLKGFLNKDPKERLGCRPQ 506
Query: 461 KSFEHVKRMRYFSEIDFNTL--RTIHPPFIPQLDNEEDVGYFD-DFTNE 506
F +K +F ID++ L + PPF PQ+ ++ + FD FT+E
Sbjct: 507 TGFSDIKSHAFFRSIDWDLLEKKQALPPFQPQITDDYGLDNFDTQFTSE 555
>CE29298 [T] KOG0690 Serine/threonine protein kinase
Length = 483
Score = 125 bits (314), Expect = 2e-28
Identities = 92/345 (26%), Positives = 141/345 (40%), Gaps = 69/345 (20%)
Query: 171 DFEMITXXXXXXXXXXXLARKKDTKEICAXXXXXXXXXXXXEGTDHVLTERDILTTTRSE 230
DF+ + L R+K + ++ A H LTE +L
Sbjct: 179 DFDFLKVLGQGTFGKVILCREKSSDKLYAIKIIRKEMVVDRSEVAHTLTENRVLYACVHP 238
Query: 231 WLVKLLYAFQDPQSLYLAMEFVPGGDFRTLLLNTKFLQAPHARFYISEMFCAVNALHQLG 290
+L L Y+FQ + MEF GG+ T L K RFY SE+ A+ LH
Sbjct: 239 FLTLLKYSFQAQYHICFVMEFANGGELFTHLQRCKTFSEARTRFYGSEIILALGYLHHRN 298
Query: 291 YTHRDLKPENFLIDSKGHIKLTDFGLASGTVSMERIESMKIRLQEVKNLEFPEFRERSMD 350
+RD+K EN L+D GHIK+TDFGL
Sbjct: 299 IVYRDMKLENLLLDRDGHIKITDFGLC--------------------------------- 325
Query: 351 DRRRMYNKLREEEVRYAHST---VGSPDYMALEVLEAKNYDFTVDYWSLGCILFESLVGY 407
+EE++Y T G+P+Y+A EV+E +YD +VD+W +G +++E + G
Sbjct: 326 ----------KEEIKYGDKTSTFCGTPEYLAPEVIEDIDYDRSVDWWGVGVVMYEMMCGR 375
Query: 408 TPFSGNSTNETYENLRNWKHVLQRPKCDNGRYAFSDRTWELITRLIADPINRLKS----- 462
PFS + +E + CD F +R L++ + R+ +
Sbjct: 376 LPFSAKENGKLFELITT---------CD---LKFPNRLSPEAVTLLSGLLERVPAKRLGA 423
Query: 463 ----FEHVKRMRYFSEIDFN-TLR-TIHPPFIPQLDNEEDVGYFD 501
V R +F ++D+ TLR + PPF P + +E D +FD
Sbjct: 424 GPDDAREVSRAEFFKDVDWEATLRKEVEPPFKPNVMSETDTSFFD 468
>CE02604 [T] KOG0695 Serine/threonine protein kinase
Length = 597
Score = 125 bits (314), Expect = 2e-28
Identities = 93/349 (26%), Positives = 152/349 (42%), Gaps = 53/349 (15%)
Query: 171 DFEMITXXXXXXXXXXXLARKKDTKEICAXXXXXXXXXXXXEGTDHVLTERDILTTTRS- 229
DF ++T A T++I A E D V TE+ + +
Sbjct: 252 DFRLLTVIGRGSYAKVVQAEHVSTRQIYAIKIIKKEMFNEDEDIDWVQTEKSVFEAASNY 311
Query: 230 EWLVKLLYAFQDPQSLYLAMEFVPGGDFRTLLLNTKFLQAPHARFYISEMFCAVNALHQL 289
+LV L FQ L+ +EFVPGGD + + L HARFY E+ A++ LH
Sbjct: 312 PFLVGLHSCFQTESRLFFVIEFVPGGDLMFHMQQQRKLPEEHARFYSGEIILALHFLHSR 371
Query: 290 GYTHRDLKPENFLIDSKGHIKLTDFGLASGTVSMERIESMKIRLQEVKNLEFPEFRERSM 349
G +RDLK +N LID++GHIKLTD+G+ + + S
Sbjct: 372 GIIYRDLKLDNVLIDAEGHIKLTDYGMCKENIKDGDLTS--------------------- 410
Query: 350 DDRRRMYNKLREEEVRYAHSTVGSPDYMALEVLEAKNYDFTVDYWSLGCILFESLVGYTP 409
+ G+P+Y+A E+L Y F+VD+W+LG ++FE + G +P
Sbjct: 411 -------------------TFCGTPNYIAPEILRGDEYGFSVDWWALGVLMFEMMAGRSP 451
Query: 410 FSGNSTNETYENLRNWKHVLQRPKCDNGRYAFSDRTWELITRLI-ADPINRL-------K 461
F + EN ++ + + + S R ++ + DP RL +
Sbjct: 452 FDIVGMQNSEENTEDYLFQIILERQIRIPRSLSVRASGILKGFLNKDPTERLGCKLDINE 511
Query: 462 SFEHVKRMRYF-SEIDFNTL--RTIHPPFIPQLDNEEDVGYFD-DFTNE 506
+K ++F ID+ L + + PP+ P ++++ D+ +FD FT+E
Sbjct: 512 GLRDMKEHQFFRGFIDWEALEQKAVAPPYHPAVESDRDLTHFDHQFTDE 560
>7301734 [T] KOG0694 Serine/threonine protein kinase
Length = 739
Score = 125 bits (314), Expect = 2e-28
Identities = 93/347 (26%), Positives = 151/347 (42%), Gaps = 60/347 (17%)
Query: 171 DFEMITXXXXXXXXXXXLARKKDTKEICAXXXXXXXXXXXXEGTDHVLTERDILTTTRSE 230
DF I LA KK T EI A + D +TE+ IL +
Sbjct: 407 DFNFIKVLGKGSFGKVMLAEKKGTDEIYAIKVLKKDAIIQDDDVDCTMTEKRILALAANH 466
Query: 231 -WLVKLLYAFQDPQSLYLAMEFVPGGDFRTLLLNTKFLQAPHARFYISEMFCAVNALHQL 289
+L L FQ P L+ ME+V GGD + + +A A FY +E+ A+ LH
Sbjct: 467 PFLTALHSCFQTPDRLFFVMEYVNGGDLMFQIQKARRFEASRAAFYAAEVTLALQFLHTH 526
Query: 290 GYTHRDLKPENFLIDSKGHIKLTDFGLASGTVSMERIESMKIRLQEVKNLEFPEFRERSM 349
G +RDLK +N L+D +GH KL DFG+ + + +
Sbjct: 527 GVIYRDLKLDNILLDQEGHCKLADFGMCKEGIMNGMLTT--------------------- 565
Query: 350 DDRRRMYNKLREEEVRYAHSTVGSPDYMALEVLEAKNYDFTVDYWSLGCILFESLVGYTP 409
+ G+PDY+A E+L+ + Y +VD+W+LG +++E + G P
Sbjct: 566 -------------------TFCGTPDYIAPEILKEQEYGASVDWWALGVLMYEMMAGQPP 606
Query: 410 FSGNSTNETYENLRNWKHVLQRPKCDNGRY-AFSDRTWELITR--LIADPINRL---KSF 463
F ++ +E ++++ + D+ Y + R I + L +P RL
Sbjct: 607 FEADNEDELFDSIMH----------DDVLYPVWLSREAVSILKGFLTKNPEQRLGCTGDE 656
Query: 464 EHVKRMRYFSEIDFNTL--RTIHPPFIPQLDNEEDVGYFD-DFTNEE 507
+++ +F+++D+ L R I PPF P++ N D FD +FT E+
Sbjct: 657 NEIRKHPFFAKLDWKELEKRNIKPPFRPKMKNPRDANNFDAEFTKED 703
>SPAC4G8.05 [R] KOG0610 Putative serine/threonine protein kinase
Length = 566
Score = 125 bits (313), Expect = 2e-28
Identities = 94/317 (29%), Positives = 149/317 (46%), Gaps = 22/317 (6%)
Query: 188 LARKKDTKEICAXXXXXXXXXXXXEGTDHVLTERDILTTTRSEWLVKLLYAFQDPQSLYL 247
L R+K + + A + E+ IL T+ ++V L ++FQ + LYL
Sbjct: 211 LVREKKSGKFYAMKVLSKQEMIKRNKSKRAFAEQHILATSNHPFIVTLYHSFQSDEYLYL 270
Query: 248 AMEFVPGGDFRTLLLNT--KFLQAPHARFYISEMFCAVNALHQLGYTHRDLKPENFLIDS 305
ME+ GG+F L + L A+FYI+E+ A+ LH +G+ +RDLKPEN L+
Sbjct: 271 CMEYCMGGEFFRALQRRPGRCLSENEAKFYIAEVTAALEYLHLMGFIYRDLKPENILLHE 330
Query: 306 KGHIKLTDFGLASGTVSMERIESMKIRLQEVKNLEFPEFRERSMDDRRRMYNKLREEEVR 365
GHI L+DF L+ + S ++ R P + D + R
Sbjct: 331 SGHIMLSDFDLSKQSNSAGAPTVIQAR-------NAPSAQNAYALDTKSCIADFR----- 378
Query: 366 YAHSTVGSPDYMALEVLEAKNYDFTVDYWSLGCILFESLVGYTPFSGNSTNETYENLRNW 425
+S VG+ +Y+A EV++ + VD+W+LG + +E L TPF G + N T+ N+ +
Sbjct: 379 -TNSFVGTEEYIAPEVIKGCGHTSAVDWWTLGILFYEMLYATTPFKGKNRNMTFSNILH- 436
Query: 426 KHVLQRPKCDNGRYAFSDRTWELITR-LIADPINRLKS---FEHVKRMRYFSEIDFNTLR 481
K V+ D + S LI + L+ D +RL S VK +F + + LR
Sbjct: 437 KDVIFPEYAD--APSISSLCKNLIRKLLVKDENDRLGSQAGAADVKLHPFFKNVQWALLR 494
Query: 482 TIHPPFIPQLDNEEDVG 498
PP IP+L ++ G
Sbjct: 495 HTEPPIIPKLAPIDEKG 511
>Hs4506071 [T] KOG0695 Serine/threonine protein kinase
Length = 587
Score = 125 bits (313), Expect = 2e-28
Identities = 98/351 (27%), Positives = 152/351 (42%), Gaps = 57/351 (16%)
Query: 170 KDFEMITXXXXXXXXXXXLARKKDTKEICAXXXXXXXXXXXXEGTDHVLTERDILTTTRS 229
+DF+++ L R K T I A E D V TE+ + +
Sbjct: 243 QDFDLLRVIGRGSYAKVLLVRLKKTDRIYAMKVVKKELVNDDEDIDWVQTEKHVFEQASN 302
Query: 230 E-WLVKLLYAFQDPQSLYLAMEFVPGGDFRTLLLNTKFLQAPHARFYISEMFCAVNALHQ 288
+LV L FQ L+ +E+V GGD + + L HARFY +E+ A+N LH+
Sbjct: 303 HPFLVGLHSCFQTESRLFFVIEYVNGGDLMFHMQRQRKLPEEHARFYSAEISLALNYLHE 362
Query: 289 LGYTHRDLKPENFLIDSKGHIKLTDFGLASGTVSMERIESMKIRLQEVKNLEFPEFRERS 348
G +RDLK +N L+DS+GHIKLTD+G+
Sbjct: 363 RGIIYRDLKLDNVLLDSEGHIKLTDYGMC------------------------------- 391
Query: 349 MDDRRRMYNKLREEEVRYAHST---VGSPDYMALEVLEAKNYDFTVDYWSLGCILFESLV 405
+E +R +T G+P+Y+A E+L ++Y F+VD+W+LG ++FE +
Sbjct: 392 ------------KEGLRPGDTTSTFCGTPNYIAPEILRGEDYGFSVDWWALGVLMFEMMA 439
Query: 406 GYTPFS--GNSTNETYENLRNWKHVLQRPKCDNGRYAFSDRTWELITRLIADPINRL--- 460
G +PF G+S N V+ + R L + L DP RL
Sbjct: 440 GRSPFDIVGSSDNPDQNTEDYLFQVILEKQIRIPRSLSVKAASVLKSFLNKDPKERLGCH 499
Query: 461 --KSFEHVKRMRYFSEIDFNTL--RTIHPPFIPQLDNEEDVGYFD-DFTNE 506
F ++ +F +D++ + + + PPF P + E + FD FTNE
Sbjct: 500 PQTGFADIQGHPFFRNVDWDMMEQKQVVPPFKPNISGEFGLDNFDSQFTNE 550
>Hs4506735 [T] KOG0603 Ribosomal protein S6 kinase
Length = 772
Score = 124 bits (311), Expect = 4e-28
Identities = 106/309 (34%), Positives = 150/309 (48%), Gaps = 65/309 (21%)
Query: 215 DHVLTERDILTTTR-SEWLVKLLYAFQDPQSLYLAMEFVPGGDFRTLLLNTKFLQAPHAR 273
+H TER +L R + +LV L YAFQ L+L +++V GG+ T L ++ + R
Sbjct: 80 EHTRTERSVLELVRQAPFLVTLHYAFQTDAKLHLILDYVSGGEMFTHLYQRQYFKEAEVR 139
Query: 274 FYISEMFCAVNALHQLGYTHRDLKPENFLIDSKGHIKLTDFGLASGTVSMERIESMKIRL 333
Y E+ A+ LH+LG +RDLK EN L+DS+GHI LTDFGL+
Sbjct: 140 VYGGEIVLALEHLHKLGIIYRDLKLENVLLDSEGHIVLTDFGLSK--------------- 184
Query: 334 QEVKNLEFPEFRERSMDDRRRMYNKLREEEVRYAHSTVGSPDYMALEVLEAK-NYDFTVD 392
EF L EE+ R S G+ +YMA E++ +K + VD
Sbjct: 185 ------EF-----------------LTEEKER-TFSFCGTIEYMAPEIIRSKTGHGKAVD 220
Query: 393 YWSLGCILFESLVGYTPFSGNSTNETYENLRNWKHVLQRP--KCDNGRYAFSDR----TW 446
+WSLG +LFE L G +PF T E RN + + R KC F R
Sbjct: 221 WWSLGILLFELLTGASPF-------TLEGERNTQAEVSRRILKCSP---PFPPRIGPVAQ 270
Query: 447 ELITRLIA-DPINRL----KSFEHVKRMRYFSEIDFNTL--RTIHPPFIPQLDNEEDVGY 499
+L+ RL+ DP RL + + V+ +F +D+ L R I PF PQ+ +E DVG
Sbjct: 271 DLLQRLLCKDPKKRLGAGPQGAQEVRNHPFFQGLDWVALAARKIPAPFRPQIRSELDVGN 330
Query: 500 F-DDFTNEE 507
F ++FT E
Sbjct: 331 FAEEFTRLE 339
>7300106 [T] KOG0690 Serine/threonine protein kinase
Length = 530
Score = 124 bits (311), Expect = 4e-28
Identities = 92/348 (26%), Positives = 150/348 (42%), Gaps = 62/348 (17%)
Query: 170 KDFEMITXXXXXXXXXXXLARKKDTKEICAXXXXXXXXXXXXEGTDHVLTERDILTTTRS 229
++FE + L R+K T ++ A + H LTE +L +T
Sbjct: 183 ENFEFLKVLGKGTFGKVILCREKATAKLYAIKILKKEVIIQKDEVAHTLTESRVLKSTNH 242
Query: 230 EWLVKLLYAFQDPQSLYLAMEFVPGGDFRTLLLNTKFLQAPHARFYISEMFCAVNALHQL 289
+L+ L Y+FQ L M++V GG+ L + + RFY +E+ A+ LH
Sbjct: 243 PFLISLKYSFQTNDRLCFVMQYVNGGELFWHLSHERIFTEDRTRFYGAEIISALGYLHSQ 302
Query: 290 GYTHRDLKPENFLIDSKGHIKLTDFGLASGTVSMERIESMKIRLQEVKNLEFPEFRERSM 349
G +RDLK EN L+D GHIK+ DFGL
Sbjct: 303 GIIYRDLKLENLLLDKDGHIKVADFGLC-------------------------------- 330
Query: 350 DDRRRMYNKLREEEVRYAHST---VGSPDYMALEVLEAKNYDFTVDYWSLGCILFESLVG 406
+E++ Y +T G+P+Y+A EVL+ +Y VD+W G +++E + G
Sbjct: 331 -----------KEDITYGRTTKTFCGTPEYLAPEVLDDNDYGQAVDWWGTGVVMYEMICG 379
Query: 407 YTPFSGNSTNETYENLRNWKHVLQRPKCDNGRYAFSDRTWELITRLIA-DPINRL----K 461
PF + + + +++ K +D L+ L+A DP RL
Sbjct: 380 RLPFYNRDHDVLFTLI-----LVEEVKFPRN---ITDEAKNLLAGLLAKDPKKRLGGGKD 431
Query: 462 SFEHVKRMRYFSEIDFN--TLRTIHPPFIPQLDNEEDVGYFD-DFTNE 506
+ ++ +F+ I++ L+ I PPF PQ+ ++ D YFD +FT E
Sbjct: 432 DVKEIQAHPFFASINWTDLVLKKIPPPFKPQVTSDTDTRYFDKEFTGE 479
>CE29092 [T] KOG0694 Serine/threonine protein kinase
Length = 707
Score = 124 bits (310), Expect = 5e-28
Identities = 90/359 (25%), Positives = 153/359 (42%), Gaps = 81/359 (22%)
Query: 171 DFEMITXXXXXXXXXXXLARKKDTKEICAXXXXXXXXXXXXEGTDHVLTERDILT-TTRS 229
DF + LA +K T E+ A + + + E+ IL+ +
Sbjct: 377 DFTFMKVLGKGSFGKVMLAERKGTDEVYAIKILKKDVIVQDDDVECTMCEKRILSLAAKH 436
Query: 230 EWLVKLLYAFQDPQSLYLAMEFVPGGDFRTLLLNTKFLQAPHARFYISEMFCAVNALHQL 289
+L L +FQ L+ ME+V GGD + + ARFY +E+ CA+ LH+
Sbjct: 437 PFLTALHSSFQTSDRLFFVMEYVNGGDLMFQIQRARKFDESRARFYAAEVTCALQFLHRN 496
Query: 290 GYTHRDLKPENFLIDSKGHIKLTDFGLASGTVSMERIESMKIRLQEVKNLEFPEFRERSM 349
+RDLK +N L+D++GH +L DFG+ ++ + + S
Sbjct: 497 DVIYRDLKLDNILLDAEGHCRLADFGMCKEGINKDNLTS--------------------- 535
Query: 350 DDRRRMYNKLREEEVRYAHSTVGSPDYMALEVLEAKNYDFTVDYWSLGCILFESLVGYTP 409
+ G+PDY+A E+L+ Y +VD+W+LG +++E + G P
Sbjct: 536 -------------------TFCGTPDYIAPEILQEMEYGVSVDWWALGVLMYEMMAGQPP 576
Query: 410 FSGNSTNETYENLRNWKHVLQRPKCDNGRYAFSDRTWELITRLIADPINRLKSF------ 463
F ++ ++ +E + N D+ Y W L + +N LK+F
Sbjct: 577 FEADNEDDLFEAILN----------DDVLYP----VW-----LSKEAVNILKAFMTKNAG 617
Query: 464 ------------EHVKRMRYFSEIDFNTL--RTIHPPFIPQLDNEEDVGYFD-DFTNEE 507
+ ++ +F EID++ L R + PPF P++ ++ D FD DFT EE
Sbjct: 618 KRLGCVVSQGGEDAIRAHPFFREIDWDALESRQVKPPFKPKIKSKRDANNFDSDFTKEE 676
>Hs10835242 [T] KOG0614 cGMP-dependent protein kinase
Length = 686
Score = 123 bits (309), Expect = 6e-28
Identities = 83/299 (27%), Positives = 140/299 (46%), Gaps = 54/299 (18%)
Query: 215 DHVLTERDILTTTRSEWLVKLLYAFQDPQSLYLAMEFVPGGDFRTLLLNTKFLQAPHARF 274
+H+ +E+ I+ S+++V+L F+D + LY+ ME GG+ T+L + + RF
Sbjct: 419 EHIRSEKQIMQGAHSDFIVRLYRTFKDSKYLYMLMEACLGGELWTILRDRGSFEDSTTRF 478
Query: 275 YISEMFCAVNALHQLGYTHRDLKPENFLIDSKGHIKLTDFGLASGTVSMERIESMKIRLQ 334
Y + + A LH G +RDLKPEN ++D +G+ KL DFG A
Sbjct: 479 YTACVVEAFAYLHSKGIIYRDLKPENLILDHRGYAKLVDFGFA----------------- 521
Query: 335 EVKNLEFPEFRERSMDDRRRMYNKLREEEVRYAHSTVGSPDYMALEVLEAKNYDFTVDYW 394
K + F + + G+P+Y+A E++ K +D + DYW
Sbjct: 522 --KKIGFG----------------------KKTWTFCGTPEYVAPEIILNKGHDISADYW 557
Query: 395 SLGCILFESLVGYTPFSGNSTNETYENLRNWKHVLQRPKCDNGRYAFSDRTWELITRLIA 454
SLG +++E L G PFSG +TY + +++ PK + LI +L
Sbjct: 558 SLGILMYELLTGSPPFSGPDPMKTYNIILRGIDMIEFPK------KIAKNAANLIKKLCR 611
Query: 455 D-PINRLKSFEH----VKRMRYFSEIDFNTLR--TIHPPFIPQLDNEEDVGYFDDFTNE 506
D P RL + ++ +++ ++F ++ LR T+ PP IP + + D FD F +
Sbjct: 612 DNPSERLGNLKNGVKDIQKHKWFEGFNWEGLRKGTLTPPIIPSVASPTDTSNFDSFPED 670
>Hs5453974 [T] KOG0694 Serine/threonine protein kinase
Length = 984
Score = 123 bits (308), Expect = 8e-28
Identities = 100/358 (27%), Positives = 156/358 (42%), Gaps = 64/358 (17%)
Query: 162 KRRLKPKHKDFEMITXXXXXXXXXXXLARKKDTKEICAXXXXXXXXXXXXEGTDHVLTER 221
++R + +DF LA K+T E+ A + D ++ E+
Sbjct: 647 QQRFQFNLQDFRCCAVLGRGHFGKVLLAEYKNTNEMFAIKALKKGDIVARDEVDSLMCEK 706
Query: 222 DILTTTRS---EWLVKLLYAFQDPQSLYLAMEFVPGGDFRTLLLNTKFLQAPHARFYISE 278
I T S +LV L FQ + + ME+ GGD + ++T P A FY +
Sbjct: 707 RIFETVNSVRHPFLVNLFACFQTKEHVCFVMEYAAGGDLM-MHIHTDVFSEPRAVFYAAC 765
Query: 279 MFCAVNALHQLGYTHRDLKPENFLIDSKGHIKLTDFGLASGTVSMERIESMKIRLQEVKN 338
+ + LH+ +RDLK +N L+D++G +K+ DFGL E M
Sbjct: 766 VVLGLQYLHEHKIVYRDLKLDNLLLDTEGFVKIADFGLCK--------EGM--------- 808
Query: 339 LEFPEFRERSMDDRRRMYNKLREEEVRYAHSTVGSPDYMALEVLEAKNYDFTVDYWSLGC 398
DR + G+P+++A EVL +Y VD+W LG
Sbjct: 809 ---------GYGDRTSTF--------------CGTPEFLAPEVLTETSYTRAVDWWGLGV 845
Query: 399 ILFESLVGYTPFSGNSTNETYENLRNWKHVLQRPKCDNGRYA--FSDRTWELITRLI-AD 455
+++E LVG +PF G+ E ++++ N D RY S ++ RL+ +
Sbjct: 846 LIYEMLVGESPFPGDDEEEVFDSIVN----------DEVRYPRFLSTEAISIMRRLLRRN 895
Query: 456 PINRL----KSFEHVKRMRYFSEIDFNTL--RTIHPPFIPQLDNEEDVGYFDD-FTNE 506
P RL K E VK+ +F ID++ L + + PPFIP + EDV FDD FT+E
Sbjct: 896 PERRLGASEKDAEDVKKHPFFRLIDWSALMDKKVKPPFIPTIRGREDVSNFDDEFTSE 953
>Hs4502023 [T] KOG0690 Serine/threonine protein kinase
Length = 481
Score = 123 bits (308), Expect = 8e-28
Identities = 98/357 (27%), Positives = 146/357 (40%), Gaps = 56/357 (15%)
Query: 154 TKETNI-LRKRRLKPKHKDFEMITXXXXXXXXXXXLARKKDTKEICAXXXXXXXXXXXXE 212
T+E + + K R K DF+ + L R+K T A +
Sbjct: 133 TEEMEVAVSKARAKVTMNDFDYLKLLGKGTFGKVILVREKATGRYYAMKILRKEVIIAKD 192
Query: 213 GTDHVLTERDILTTTRSEWLVKLLYAFQDPQSLYLAMEFVPGGDFRTLLLNTKFLQAPHA 272
H +TE +L TR +L L YAFQ L ME+ GG+ L + A
Sbjct: 193 EVAHTVTESRVLQNTRHPFLTALKYAFQTHDRLCFVMEYANGGELFFHLSRERVFTEERA 252
Query: 273 RFYISEMFCAVNALHQLGYTHRDLKPENFLIDSKGHIKLTDFGLASGTVSMERIESMKIR 332
RFY +E+ A+ LH +RD+K EN ++D GHIK+TDFGL +S
Sbjct: 253 RFYGAEIVSALEYLHSRDVVYRDIKLENLMLDKDGHIKITDFGLCKEGIS---------- 302
Query: 333 LQEVKNLEFPEFRERSMDDRRRMYNKLREEEVRYAHSTVGSPDYMALEVLEAKNYDFTVD 392
D M + G+P+Y+A EVLE +Y VD
Sbjct: 303 ------------------DGATM------------KTFCGTPEYLAPEVLEDNDYGRAVD 332
Query: 393 YWSLGCILFESLVGYTPFSGNSTNETYENLRNWKHVLQRPKCDNGRYAFSDRTWELITRL 452
+W LG +++E + G PF +E + ++ P+ S L+ L
Sbjct: 333 WWGLGVVMYEMMCGRLPFYNQDHERLFELI--LMEEIRFPR------TLSPEAKSLLAGL 384
Query: 453 I-ADPINRL----KSFEHVKRMRYFSEIDFNTL--RTIHPPFIPQLDNEEDVGYFDD 502
+ DP RL + V R+F I++ + + + PPF PQ+ +E D YFDD
Sbjct: 385 LKKDPKQRLGGGPSDAKEVMEHRFFLSINWQDVVQKKLLPPFKPQVTSEVDTRYFDD 441
>At3g10540 [T] KOG0592 3-phosphoinositide-dependent protein kinase (PDK1)
Length = 483
Score = 122 bits (307), Expect = 1e-27
Identities = 91/323 (28%), Positives = 143/323 (44%), Gaps = 43/323 (13%)
Query: 169 HKDFEMITXXXXXXXXXXXLARKKDTKEICAXXXXXXXXXXXXEGTDHVLTERDILTTTR 228
+ DFE+ A+KKD + A T +V ER +L
Sbjct: 39 YHDFELGKIYGVGSYSKVVRAKKKDNGTVYALKIMDKKFITKENKTAYVKLERIVLDQLE 98
Query: 229 SEWLVKLLYAFQDPQSLYLAMEFVPGGDFRTLLLNTKFLQAPHARFYISEMFCAVNALHQ 288
+VKL + FQD QSLY+A+E GG+ + L ARFY +E+ A+ +H
Sbjct: 99 HPGIVKLFFTFQDTQSLYMALESCEGGELFDQITRKGRLSEDEARFYSAEVVDALEYIHN 158
Query: 289 LGYTHRDLKPENFLIDSKGHIKLTDFGLASGTVSMERIESMKIRLQEVKNLEFPEFRERS 348
+G HRD+KPEN L+ GHIK+ DFG ++ +++ + +
Sbjct: 159 MGLIHRDIKPENLLLTLDGHIKIADFG----------------SVKPMQDSQITVLPNAA 202
Query: 349 MDDRRRMYNKLREEEVRYAHSTVGSPDYMALEVLEAKNYDFTVDYWSLGCILFESLVGYT 408
DD+ A + VG+ Y+ EVL + F D W+LGC L++ L G +
Sbjct: 203 SDDK--------------ACTFVGTAAYVPPEVLNSSPATFGNDLWALGCTLYQMLSGTS 248
Query: 409 PFSGNSTNETYENLRNWKHVLQRPKCDNGRYAFSDRTWELITRLI-ADPINR----LKSF 463
PF S ++ + + + K N FS+ +LI RL+ DP R + +
Sbjct: 249 PFKDASEWLIFQRI-----IARDIKFPN---HFSEAARDLIDRLLDTDPSRRPGAGSEGY 300
Query: 464 EHVKRMRYFSEIDFNTLRTIHPP 486
+ +KR +F +D+ LR+ PP
Sbjct: 301 DSLKRHPFFKGVDWKNLRSQTPP 323
>CE19898 [T] KOG0614 cGMP-dependent protein kinase
Length = 737
Score = 122 bits (306), Expect = 1e-27
Identities = 82/296 (27%), Positives = 137/296 (45%), Gaps = 53/296 (17%)
Query: 215 DHVLTERDILTTTRSEWLVKLLYAFQDPQSLYLAMEFVPGGDFRTLLLNTKFLQAPHARF 274
+H+ ER+I+ T ++W+VKL F+D + +Y+ +E GG+ T L + ARF
Sbjct: 470 EHIFAERNIMMETSTDWIVKLYKTFRDQKFVYMLLEVCLGGELWTTLRDRGHFDDYTARF 529
Query: 275 YISEMFCAVNALHQLGYTHRDLKPENFLIDSKGHIKLTDFGLASGTVSMERIESMKIRLQ 334
Y++ + + LH+ +RDLKPEN L+ + G++KL DFG A S
Sbjct: 530 YVACVLEGLEYLHRKNIVYRDLKPENCLLANTGYLKLVDFGFAKKLAS------------ 577
Query: 335 EVKNLEFPEFRERSMDDRRRMYNKLREEEVRYAHSTVGSPDYMALEVLEAKNYDFTVDYW 394
R + G+P+Y++ E++ K +D DYW
Sbjct: 578 -----------------------------GRKTWTFCGTPEYVSPEIILNKGHDQAADYW 608
Query: 395 SLGCILFESLVGYTPFSGNSTNETYENLRNWKHVLQRPKCDNGRYAFSDRTWELITRLIA 454
+LG + E ++G PF + +TY + L+ P G+ A + L+ +L
Sbjct: 609 ALGIYICELMLGRPPFQASDPMKTYTLILKGVDALEIPNRRIGKTATA-----LVKKLCR 663
Query: 455 D-PINRLKS----FEHVKRMRYFSEIDFNTL--RTIHPPFIPQLDNEEDVGYFDDF 503
D P RL S +++ R+F D+ L RT+ PP +P++ N DV FD++
Sbjct: 664 DNPGERLGSGSGGVNDIRKHRWFMGFDWEGLRSRTLKPPILPKVSNPADVTNFDNY 719
>CE19897 [T] KOG0614 cGMP-dependent protein kinase
Length = 780
Score = 122 bits (306), Expect = 1e-27
Identities = 82/296 (27%), Positives = 137/296 (45%), Gaps = 53/296 (17%)
Query: 215 DHVLTERDILTTTRSEWLVKLLYAFQDPQSLYLAMEFVPGGDFRTLLLNTKFLQAPHARF 274
+H+ ER+I+ T ++W+VKL F+D + +Y+ +E GG+ T L + ARF
Sbjct: 513 EHIFAERNIMMETSTDWIVKLYKTFRDQKFVYMLLEVCLGGELWTTLRDRGHFDDYTARF 572
Query: 275 YISEMFCAVNALHQLGYTHRDLKPENFLIDSKGHIKLTDFGLASGTVSMERIESMKIRLQ 334
Y++ + + LH+ +RDLKPEN L+ + G++KL DFG A S
Sbjct: 573 YVACVLEGLEYLHRKNIVYRDLKPENCLLANTGYLKLVDFGFAKKLAS------------ 620
Query: 335 EVKNLEFPEFRERSMDDRRRMYNKLREEEVRYAHSTVGSPDYMALEVLEAKNYDFTVDYW 394
R + G+P+Y++ E++ K +D DYW
Sbjct: 621 -----------------------------GRKTWTFCGTPEYVSPEIILNKGHDQAADYW 651
Query: 395 SLGCILFESLVGYTPFSGNSTNETYENLRNWKHVLQRPKCDNGRYAFSDRTWELITRLIA 454
+LG + E ++G PF + +TY + L+ P G+ A + L+ +L
Sbjct: 652 ALGIYICELMLGRPPFQASDPMKTYTLILKGVDALEIPNRRIGKTATA-----LVKKLCR 706
Query: 455 D-PINRLKS----FEHVKRMRYFSEIDFNTL--RTIHPPFIPQLDNEEDVGYFDDF 503
D P RL S +++ R+F D+ L RT+ PP +P++ N DV FD++
Sbjct: 707 DNPGERLGSGSGGVNDIRKHRWFMGFDWEGLRSRTLKPPILPKVSNPADVTNFDNY 762
>Hs5453976 [T] KOG0694 Serine/threonine protein kinase
Length = 706
Score = 120 bits (301), Expect = 6e-27
Identities = 89/358 (24%), Positives = 153/358 (41%), Gaps = 57/358 (15%)
Query: 164 RLKPKHKDFEMITXXXXXXXXXXXLARKKDTKEICAXXXXXXXXXXXXEGTDHVLTERDI 223
++K K +DF + LA K T + A + + + E+ +
Sbjct: 372 QIKLKIEDFILHKMLGKGSFGKVFLAEFKKTNQFFAIKALKKDVVLMDDDVECTMVEKRV 431
Query: 224 LTTT-RSEWLVKLLYAFQDPQSLYLAMEFVPGGDFRTLLLNTKFLQAPHARFYISEMFCA 282
L+ +L + FQ ++L+ ME++ GGD + + A FY +E+
Sbjct: 432 LSLAWEHPFLTHMFCTFQTKENLFFVMEYLNGGDLMYHIQSCHKFDLSRATFYAAEIILG 491
Query: 283 VNALHQLGYTHRDLKPENFLIDSKGHIKLTDFGLASGTVSMERIESMKIRLQEVKNLEFP 342
+ LH G +RDLK +N L+D GHIK+ DFG+
Sbjct: 492 LQFLHSKGIVYRDLKLDNILLDKDGHIKIADFGMC------------------------- 526
Query: 343 EFRERSMDDRRRMYNKLREEEVRYAHSTVGSPDYMALEVLEAKNYDFTVDYWSLGCILFE 402
+E + D + ++ G+PDY+A E+L + Y+ +VD+WS G +L+E
Sbjct: 527 --KENMLGDAK-------------TNTFCGTPDYIAPEILLGQKYNHSVDWWSFGVLLYE 571
Query: 403 SLVGYTPFSGNSTNETYENLRNWKHVLQRPKCDNGRYA--FSDRTWELITRL-IADPINR 459
L+G +PF G E + ++R DN Y +L+ +L + +P R
Sbjct: 572 MLIGQSPFHGQDEEELFHSIR----------MDNPFYPRWLEKEAKDLLVKLFVREPEKR 621
Query: 460 LKSFEHVKRMRYFSEIDFNTL--RTIHPPFIPQLDNEEDVGYFD-DFTNEEHMARYVD 514
L +++ F EI++ L + I PPF P++ + D FD +F NE+ + D
Sbjct: 622 LGVRGDIRQHPLFREINWEELERKEIDPPFRPKVKSPFDCSNFDKEFLNEKPRLSFAD 679
>At1g51170 [R] KOG0610 Putative serine/threonine protein kinase
Length = 404
Score = 120 bits (301), Expect = 6e-27
Identities = 85/295 (28%), Positives = 143/295 (47%), Gaps = 31/295 (10%)
Query: 226 TTRSEWLVKLLYAFQDPQSLYLAMEFVPGGDFRTLLL--NTKFLQAPHARFYISEMFCAV 283
T + +L KLL + + + + A+ + GGD L N + +FY++E+ CA+
Sbjct: 82 TNPNPFLPKLLASSESSEFIAWALPYCSGGDLNVLRQRQNDGVFSSSVIKFYLAEIVCAL 141
Query: 284 NALHQLGYTHRDLKPENFLIDSKGHIKLTDFGLASGTVSMERIESMKIRLQE-----VKN 338
+ LH +G +RDLKPEN L+ GH+ LTDF L+ R E + E N
Sbjct: 142 DHLHTMGIAYRDLKPENILLQESGHVTLTDFDLSCSLNKPTRPEFYHLSDPEPDPNPESN 201
Query: 339 LEFPE-----FRERSMDDRRRMYNKLREEEVRY-----AHSTVGSPDYMALEVLEAKNYD 388
L + FR++ + N + + + ++S VG+ +Y++ EV+ +D
Sbjct: 202 LSHNKKSLRIFRQKKKKTKSARVNPITRRRLSFSGGERSNSFVGTDEYISPEVIRGDGHD 261
Query: 389 FTVDYWSLGCILFESLVGYTPFSGNSTNETYENLRNWKHVLQRPKCDNGRYAFSDRTWEL 448
F VD+W+LG + +E + G TPF G + ET+ N+ +++ P+ SD T +L
Sbjct: 262 FAVDWWALGVLTYEMMYGETPFKGRNKKETFRNV-----LVKEPEFAGKP---SDLT-DL 312
Query: 449 ITR-LIADPINRL---KSFEHVKRMRYFSEIDFNTL-RTIHPPFIPQLDNEEDVG 498
I R L+ DP R + +K +F + + L + PPFIP D+ + G
Sbjct: 313 IRRLLVKDPTKRFGFWRGAAEIKEHAFFKGVRWELLTEVLRPPFIPLRDDGDLTG 367
>7294770 [T] KOG0603 Ribosomal protein S6 kinase
Length = 1207
Score = 120 bits (301), Expect = 6e-27
Identities = 92/303 (30%), Positives = 149/303 (48%), Gaps = 54/303 (17%)
Query: 215 DHVLTERDILTTT-RSEWLVKLLYAFQDPQSLYLAMEFVPGGDFRTLLLNTKFLQAPHAR 273
+H TER +L R+ +LV L YAFQ LYL ++F GG+ T L +++ + R
Sbjct: 308 EHTKTERVVLEAIQRNPFLVSLHYAFQSSSKLYLVLDFANGGELFTHLYHSENFEESRVR 367
Query: 274 FYISEMFCAVNALHQLGYTHRDLKPENFLIDSKGHIKLTDFGLASGTVSMERIESMKIRL 333
YI+E+ A+ LHQLG +RD+K EN L+D +GHI L+DFGL+ KI
Sbjct: 368 VYIAEVVLALEQLHQLGIIYRDIKLENILLDGEGHIVLSDFGLS------------KI-- 413
Query: 334 QEVKNLEFPEFRERSMDDRRRMYNKLREEEVRYAHSTVGSPDYMALEVLEA--KNYDFTV 391
L E AHS G+ +YMA E++ +D V
Sbjct: 414 -------------------------LTAENEYRAHSFCGTLEYMAPEIIRTGPPGHDSAV 448
Query: 392 DYWSLGCILFESLVGYTPFSGNSTNETYENLRNWKHVLQRPKCDNGRYAFSDRTWELITR 451
D+WS+G + FE L G +PF+ S + ++ + + ++P + +FS + + +
Sbjct: 449 DWWSVGVLTFELLTGASPFA-TSDGQVQQSEISRRIQKEQPMIPS---SFSANARDFVLK 504
Query: 452 LI-ADPINRL----KSFEHVKRMRYFSEIDFNTLRTIH--PPFIPQLDNEEDVGYF-DDF 503
++ +P RL + +K +F+ I++ LRT P+ P L E+DV F ++F
Sbjct: 505 MLEKNPKRRLGGNHRDASEIKEHPFFNGINWQELRTKRRKAPYKPTLTAEDDVQNFSNEF 564
Query: 504 TNE 506
T++
Sbjct: 565 TDQ 567
>7301971 [T] KOG0616 cAMP-dependent protein kinase catalytic subunit (PKA)
Length = 356
Score = 119 bits (299), Expect = 9e-27
Identities = 77/343 (22%), Positives = 154/343 (44%), Gaps = 56/343 (16%)
Query: 171 DFEMITXXXXXXXXXXXLARKKDTKEICAXXXXXXXXXXXXEGTDHVLTERDILTTTRSE 230
D+E+ L R++++ A + HV++E+++L +
Sbjct: 46 DYEIKATLGSGSFGKVQLVRERESGVYYASKQLSKDQIVKTKQVSHVMSEKNVLRSMTFP 105
Query: 231 WLVKLLYAFQDPQSLYLAMEFVPGGDFRTLLLNTKFLQAPHARFYISEMFCAVNALHQLG 290
V L+ +++D SLYL + + GG+ T + ARFY +++F A+ LH
Sbjct: 106 NTVNLIASYKDFDSLYLVLPLIGGGELFTYHRKVRKFTEKQARFYAAQVFLALEYLHHCS 165
Query: 291 YTHRDLKPENFLIDSKGHIKLTDFGLASGTVSMERIESMKIRLQEVKNLEFPEFRERSMD 350
+RDLKPEN ++D G++K+TDFG A +++E+ + L
Sbjct: 166 LLYRDLKPENIMMDKNGYLKVTDFGFA------KKVETRTMTL----------------- 202
Query: 351 DRRRMYNKLREEEVRYAHSTVGSPDYMALEVLEAKNYDFTVDYWSLGCILFESLVGYTPF 410
G+P+Y+ E++++K Y +VD+W+ G ++FE + G++PF
Sbjct: 203 --------------------CGTPEYLPPEIIQSKPYGTSVDWWAFGVLVFEFVAGHSPF 242
Query: 411 SGNSTNETYENLRNWKHVLQRPKCDNGRYAFSDRTWELITRLIADPI-----NRLKSFEH 465
S ++ + + + + P FS L+ L+ + N +
Sbjct: 243 SAHNRDVMSMYNKICEADYKMPS------YFSGALRHLVDHLLQVDLSKRFGNLINGNRD 296
Query: 466 VKRMRYFSEIDFNTL--RTIHPPFIPQLDNEEDVGYFDDFTNE 506
+K +F ++++ L +T++ P++P + N ED+ FD +++
Sbjct: 297 IKEHEWFKDVEWIPLLNQTVNAPYVPNISNPEDISNFDKVSDK 339
>CE15475 [T] KOG0616 cAMP-dependent protein kinase catalytic subunit (PKA)
Length = 375
Score = 119 bits (298), Expect = 1e-26
Identities = 71/256 (27%), Positives = 115/256 (44%), Gaps = 43/256 (16%)
Query: 171 DFEMITXXXXXXXXXXXLARKKDTKEICAXXXXXXXXXXXXEGTDHVLTERDILTTTRSE 230
DF+ I L + K + A + +H L E+ IL
Sbjct: 51 DFDRIKTLGTGSFGRVMLVKHKQSGNYYAMKILDKQKVVKLKQVEHTLNEKRILQAIDFP 110
Query: 231 WLVKLLYAFQDPQSLYLAMEFVPGGDFRTLLLNTKFLQAPHARFYISEMFCAVNALHQLG 290
+LV + ++F+D +LY+ +EF+ GG+ + L PH+RFY +++ A LH L
Sbjct: 111 FLVNMTFSFKDNSNLYMVLEFISGGEMFSHLRRIGRFSEPHSRFYAAQIVLAFEYLHSLD 170
Query: 291 YTHRDLKPENFLIDSKGHIKLTDFGLASGTVSMERIESMKIRLQEVKNLEFPEFRERSMD 350
+RDLKPEN LIDS G++K+TDFG A + VK +
Sbjct: 171 LIYRDLKPENLLIDSTGYLKITDFGFA----------------KRVKGRTW--------- 205
Query: 351 DRRRMYNKLREEEVRYAHSTVGSPDYMALEVLEAKNYDFTVDYWSLGCILFESLVGYTPF 410
+ G+P+Y+A E++ +K Y+ VD+W+LG +++E GY PF
Sbjct: 206 ------------------TLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPF 247
Query: 411 SGNSTNETYENLRNWK 426
+ + YE + + K
Sbjct: 248 FADQPIQIYEKIVSGK 263
>YBR028c [RT] KOG0598 Ribosomal protein S6 kinase and related proteins
Length = 525
Score = 119 bits (297), Expect = 2e-26
Identities = 66/200 (33%), Positives = 102/200 (51%), Gaps = 30/200 (15%)
Query: 215 DHVLTERDILTTTRSEWLVKLLYAFQDPQSLYLAMEFVPGGDFRTLLLNTKFLQAPHARF 274
+ ER IL+ +VKL Y+F D LYL ++++PGG+ L L F
Sbjct: 197 ERTFAERSILSEIEHPNIVKLFYSFHDNSKLYLLLQYIPGGELFYHLKEHGTLDETTVSF 256
Query: 275 YISEMFCAVNALHQLGYTHRDLKPENFLIDSKGHIKLTDFGLASGTVSMERIESMKIRLQ 334
Y +E+ CA+ LH G +RDLKPEN L++ +GH+ LTDFGL+ + + ++
Sbjct: 257 YAAEISCALRFLHTKGVVYRDLKPENCLLNQRGHLVLTDFGLSKKSANDSAVDE------ 310
Query: 335 EVKNLEFPEFRERSMDDRRRMYNKLREEEVRYAHSTVGSPDYMALEVLEAKNYDFTVDYW 394
E P E V +S +G+P+Y A E+L K Y D++
Sbjct: 311 -----EDP-------------------ENVNALYSIIGTPEYCAPEILLGKAYSQNCDWY 346
Query: 395 SLGCILFESLVGYTPFSGNS 414
SLGC+L++ LVG P++G++
Sbjct: 347 SLGCLLYDMLVGKPPYTGSN 366
>SPBC725.06c [R] KOG0605 NDR and related serine/threonine kinases
Length = 1032
Score = 119 bits (297), Expect = 2e-26
Identities = 90/323 (27%), Positives = 142/323 (43%), Gaps = 60/323 (18%)
Query: 233 VKLLYAFQDPQSLYLAMEFVPGGDFRTLLLNTKFLQAPHARFYISEMFCAVNALHQLGYT 292
VKL YAF L L M++ GGD TL+ L Y +E+ A+ LHQ G
Sbjct: 590 VKLYYAFDSGDYLCLVMDYFNGGDCETLIQKLGPLPEQWVCQYAAELLNAIELLHQDGII 649
Query: 293 HRDLKPENFLIDSKGHIKLTDFGLASGTVSMERIESMKIR-------------------- 332
H D+KP N L+D GHI+LTDFGL+ + + + R
Sbjct: 650 HHDIKPANMLVDETGHIRLTDFGLSENVEEKKEVYKLTKRMSFEQKHGNLYEQLQPKKFE 709
Query: 333 -----------LQEVKNLEFP---------------EFRERSMDDR--RRMYNKLREEEV 364
+ E++ E P +F +MD+ + N+L ++E
Sbjct: 710 FVRYVRNYRGNIDELEKAESPQQNSDYANDSVQHLLDFDINNMDETAIHMLMNQLEKKEN 769
Query: 365 R--YAHSTVGSPDYMALEVLEAKNYDFTVDYWSLGCILFESLVGYTPFSGNSTNETYENL 422
R G+P+YMA E+L + D W++GC++FE L G PF N+ + +
Sbjct: 770 RTFIKKDISGTPNYMAPEILMGVDTQMG-DIWAMGCVIFEMLTGTRPFEANTVKAIWARI 828
Query: 423 -RNWKHVLQRPKCDNGRYAFSDRTWELITRLIADPINR---LKSFEHVKRMRYFSEIDFN 478
RN +R K + S +LIT+L+ N+ ++ +K+ +F I ++
Sbjct: 829 ERNDIGWTKRVK-----ESCSKEAVDLITKLMDPDCNKRLGSNGYQEIKKHPFFRTIKWD 883
Query: 479 TLRTIHPPFIPQLDNEEDVGYFD 501
L + PF+PQ +N ED+ YF+
Sbjct: 884 NLNSGPGPFVPQTENVEDLTYFE 906
>At5g04510 [T] KOG0592 3-phosphoinositide-dependent protein kinase (PDK1)
Length = 488
Score = 119 bits (297), Expect = 2e-26
Identities = 89/321 (27%), Positives = 142/321 (43%), Gaps = 43/321 (13%)
Query: 171 DFEMITXXXXXXXXXXXLARKKDTKEICAXXXXXXXXXXXXEGTDHVLTERDILTTTRSE 230
DFE A+KK+T + A T +V ER +L
Sbjct: 40 DFEFGKIYGVGSYSKVVRAKKKETGTVYALKIMDKKFITKENKTAYVKLERIVLDQLEHP 99
Query: 231 WLVKLLYAFQDPQSLYLAMEFVPGGDFRTLLLNTKFLQAPHARFYISEMFCAVNALHQLG 290
++KL + FQD SLY+A+E GG+ + L ARFY +E+ A+ +H +G
Sbjct: 100 GIIKLYFTFQDTSSLYMALESCEGGELFDQITRKGRLSEDEARFYTAEVVDALEYIHSMG 159
Query: 291 YTHRDLKPENFLIDSKGHIKLTDFGLASGTVSMERIESMKIRLQEVKNLEFPEFRERSMD 350
HRD+KPEN L+ S GHIK+ DFG ++ +++ + + D
Sbjct: 160 LIHRDIKPENLLLTSDGHIKIADFG----------------SVKPMQDSQITVLPNAASD 203
Query: 351 DRRRMYNKLREEEVRYAHSTVGSPDYMALEVLEAKNYDFTVDYWSLGCILFESLVGYTPF 410
D+ A + VG+ Y+ EVL + F D W+LGC L++ L G +PF
Sbjct: 204 DK--------------ACTFVGTAAYVPPEVLNSSPATFGNDLWALGCTLYQMLSGTSPF 249
Query: 411 SGNSTNETYENLRNWKHVLQRPKCDNGRYAFSDRTWELITRLI-ADPINR----LKSFEH 465
S ++ + + + K N FS+ +LI RL+ +P R + +
Sbjct: 250 KDASEWLIFQRI-----IARDIKFPN---HFSEAARDLIDRLLDTEPSRRPGAGSEGYVA 301
Query: 466 VKRMRYFSEIDFNTLRTIHPP 486
+KR +F+ +D+ LR+ PP
Sbjct: 302 LKRHPFFNGVDWKNLRSQTPP 322
>At5g03640 [R] KOG0610 Putative serine/threonine protein kinase
Length = 926
Score = 119 bits (297), Expect = 2e-26
Identities = 103/340 (30%), Positives = 154/340 (45%), Gaps = 58/340 (17%)
Query: 219 TERDILTTTRSEWLVKLLYAFQDPQSLYLAMEFVPGGDFRTLLLNT--KFLQAPHARFYI 276
TE+DIL +L L F L ME PGGD L ++ P ARFY+
Sbjct: 588 TEKDILKMLDHPFLPTLYAHFTSDNLSCLVMECCPGGDLHVLRQKQPGRWFPEPAARFYV 647
Query: 277 SEMFCAVNALHQLGYTHRDLKPENFLIDSKGHIKLTDFGLA-SGTVSMERIESMK----- 330
+E+ A+ LH LG +RDLKPEN L+ GHI +TDF L+ TVS + S
Sbjct: 648 AEVLLALEYLHMLGVIYRDLKPENILVRDDGHIMVTDFDLSLRCTVSPTLLNSSSPLHAD 707
Query: 331 -IRLQEVKN-----LEFPEFR---------ERSMDDRRRMYNKLREEEV----------- 364
+RL +E FR ++ R M KL++ ++
Sbjct: 708 AMRLSSGSRTGSNCIEPSCFRPKLSRGSGPKKKGKQHRMMMKKLKKSDLIARFKSLPQLV 767
Query: 365 -----RYAHSTVGSPDYMALEVLEAKNYDFTVDYWSLGCILFESLVGYTPFSGNSTNETY 419
++S VG+ +Y+A E+++ + + VD+W+ G L+E L G TPF G + ET
Sbjct: 768 AEPTDARSNSFVGTHEYLAPEIIKGEGHGAAVDWWTFGIFLYELLYGKTPFKGATNEETI 827
Query: 420 ENLRNWKHVLQRPKC-DNGRYAFSDRTWELIT-RLIADPINRL---KSFEHVKRMRYFSE 474
N+ VLQ K DN +F + +LI L+ +P NRL K +KR +F
Sbjct: 828 ANV-----VLQSLKFPDNPNVSFQAK--DLIRGLLVKEPENRLGTEKGAAEIKRHAFFEG 880
Query: 475 IDFNTLRTIHPPFIPQLDNEEDVGYFDDFTNEEHMARYVD 514
+++ +R PP +P Y N+E + Y+D
Sbjct: 881 LNWALIRCAIPPELPDF-------YDYGVPNQEGKSNYLD 913
>7300437 [TR] KOG0606 Microtubule-associated serine/threonine kinase and
related proteins
Length = 866
Score = 119 bits (297), Expect = 2e-26
Identities = 68/191 (35%), Positives = 102/191 (52%), Gaps = 2/191 (1%)
Query: 128 INYLEEQRRSNLMGTEQITNEWQGYLTKETNILRKRRLKPKHKDFEMITXXXXXXXXXXX 187
I+Y ++ +L+ +EQ+ ++ TK N + +L P KDF +I
Sbjct: 14 IDYKTPKKTHSLIDSEQLLDKINILTTKPENHSQNAKL-PTIKDFVIIKPISRGAFGKVF 72
Query: 188 LARKK-DTKEICAXXXXXXXXXXXXEGTDHVLTERDILTTTRSEWLVKLLYAFQDPQSLY 246
L K D+K + A V+TER+ L +RS++ V L Y+ Q +Y
Sbjct: 73 LGYKNNDSKRLFAIKVMRKSEMINKNMVSQVITERNALALSRSQFCVSLFYSLQSLSYVY 132
Query: 247 LAMEFVPGGDFRTLLLNTKFLQAPHARFYISEMFCAVNALHQLGYTHRDLKPENFLIDSK 306
L ME++ GGD ++LL + P ARFY++EM A+ LHQ G HRD+KP+N L+ S
Sbjct: 133 LVMEYMVGGDLKSLLAMFGYFDEPTARFYVAEMVMALQYLHQHGIVHRDIKPDNMLLSSS 192
Query: 307 GHIKLTDFGLA 317
GH+KLTDFGL+
Sbjct: 193 GHVKLTDFGLS 203
Score = 85.9 bits (211), Expect = 2e-16
Identities = 44/139 (31%), Positives = 77/139 (54%), Gaps = 5/139 (3%)
Query: 371 VGSPDYMALEVLEAKNYDFTVDYWSLGCILFESLVGYTPFSGNSTNETYENLRNWKHVLQ 430
+G+PDY+A E+L + + VD+W+LG +E + G PF+ + + ++N+ N ++
Sbjct: 724 LGTPDYLAPELLLKQGHGPAVDWWALGVCFYEFMTGIPPFNDETPQKVFDNILNKN--IE 781
Query: 431 RPKCDNGRYAFSDRTWELITRLIADPINRLKSFEHVKRMRYFSEIDFNTLRTIHPPFIPQ 490
P+ D A S + E + L+ N + + V++MR+F+ ID+ + PPF+P
Sbjct: 782 WPEGDE---ALSVESMEAVELLLTMDPNERPAAKEVQQMRHFACIDWENIGNTEPPFVPT 838
Query: 491 LDNEEDVGYFDDFTNEEHM 509
DN D GYFD N +H+
Sbjct: 839 PDNPTDTGYFDARNNLQHL 857
>YOL100w [T] KOG0592 3-phosphoinositide-dependent protein kinase (PDK1)
Length = 1081
Score = 118 bits (296), Expect = 2e-26
Identities = 84/326 (25%), Positives = 144/326 (43%), Gaps = 38/326 (11%)
Query: 153 LTKETNILRKRRLKPKHKDFEMITXXXXXXXXXXXLARKKDTKEICAXXXXXXXXXXXXE 212
+ KE++ +K +K KDF+ + LA DTK+ A +
Sbjct: 160 IAKESSKAQKNIIKKGIKDFKFGSVIGDGAYSTVMLATSIDTKKRYAAKVLNKEYLIRQK 219
Query: 213 GTDHVLTERDILTT-TRSEWLVKLLYAFQDPQSLYLAMEFVPGGDFRTLLLNTKFLQAPH 271
+V E+ L S +V+L FQD SLY +E+ P GDF +L+ L
Sbjct: 220 KVKYVSIEKTALQKLNNSPSVVRLFSTFQDESSLYFLLEYAPNGDFLSLMKKYGSLDETC 279
Query: 272 ARFYISEMFCAVNALHQLGYTHRDLKPENFLIDSKGHIKLTDFGLASGTVSMERIESMKI 331
AR+Y +++ A++ LH G HRD+KPEN L+D + IKLTDFG A K+
Sbjct: 280 ARYYAAQIIDAIDYLHSNGIIHRDIKPENILLDGEMKIKLTDFGTA------------KL 327
Query: 332 RLQEVKNLEFPEFRERSMDDRRRMYNKLREEEVRYAHSTVGSPDYMALEVLEAKNYDFTV 391
++ PE+ + R + S VG+ +Y++ E+L D+
Sbjct: 328 LNPTNNSVSKPEY---DLSTRSK--------------SFVGTAEYVSPELLNDSFTDYRC 370
Query: 392 DYWSLGCILFESLVGYTPFSGNSTNETYENLRNWKHVLQRPKCDNGRYAFSDRTWELITR 451
D W+ GCILF+ + G PF + T++ + ++ F +L+ +
Sbjct: 371 DIWAFGCILFQMIAGKPPFKATNEYLTFQKVMKVQYAFTP--------GFPLIIRDLVKK 422
Query: 452 LIADPINRLKSFEHVKRMRYFSEIDF 477
++ ++R + +K +F +++F
Sbjct: 423 ILVKNLDRRLTISQIKEHHFFKDLNF 448
>7296166 [T] KOG0614 cGMP-dependent protein kinase
Length = 768
Score = 118 bits (296), Expect = 2e-26
Identities = 91/324 (28%), Positives = 148/324 (45%), Gaps = 58/324 (17%)
Query: 189 ARKKDTKEICAXXXXXXXXXXXXEGTDHVLTERDILTTTRSEWLVKLLYAFQDPQSLYLA 248
A +D +I A + +H+ +ER I+ ++RS ++ +L F+D + +Y+
Sbjct: 476 AHHQDRVDIFALKCLKKRHIVDTKQEEHIFSERHIMLSSRSPFICRLYRTFRDEKYVYML 535
Query: 249 MEFVPGGDFRTLLLNTKFLQAPHARFYISEMFCAVNALHQLGYTHRDLKPENFLIDSKGH 308
+E GG+ T+L + + A+F I + A LH G +RDLKPEN ++D +G+
Sbjct: 536 LEACMGGEIWTMLRDRGSFEDNAAQFIIGCVLQAFEYLHARGIIYRDLKPENLMLDERGY 595
Query: 309 IKLTDFGLAS--GTVSMERIESMKIRLQEVKNLEFPEFRERSMDDRRRMYNKLREEEVRY 366
+K+ DFG A GT S K F
Sbjct: 596 VKIVDFGFAKQIGTSS--------------KTWTF------------------------- 616
Query: 367 AHSTVGSPDYMALEVLEAKNYDFTVDYWSLGCILFESLVGYTPFSGNSTNETYENLRNWK 426
G+P+Y+A E++ K +D VDYW+LG ++ E L G PFS +TY +
Sbjct: 617 ----CGTPEYVAPEIILNKGHDRAVDYWALGILIHELLNGTPPFSAPDPMQTYNLILKGI 672
Query: 427 HVLQRPKCDNGRYAFSDRTWELITRLIAD-PINRL----KSFEHVKRMRYFSEIDFNTL- 480
++ PK R+A +LI RL D P RL + +K+ ++F D++ L
Sbjct: 673 DMIAFPK-HISRWAV-----QLIKRLCRDVPSERLGYQTGGIQDIKKHKWFLGFDWDGLA 726
Query: 481 -RTIHPPFIPQLDNEEDVGYFDDF 503
+ + PPF+ + + DV YFD F
Sbjct: 727 SQLLIPPFVRPIAHPTDVRYFDRF 750
>YBL105c [T] KOG0694 Serine/threonine protein kinase
Length = 1151
Score = 118 bits (295), Expect = 3e-26
Identities = 90/360 (25%), Positives = 154/360 (42%), Gaps = 72/360 (20%)
Query: 163 RRLKPKHKDFEMITXXXXXXXXXXXLARKKDTKEICAXXXXXXXXXXXXEGTDHVLTERD 222
+R K +F ++ L++ K+T +CA + E+
Sbjct: 815 KRRKVSLDNFVLLKVLGKGNFGKVILSKSKNTDRLCAIKVLKKDNIIQNHDIESARAEKK 874
Query: 223 IL---TTTRSEWLVKLLYAFQDPQSLYLAMEFVPGGDFRTLLLNTKFLQAPHARFYISEM 279
+ T T+ +L L +FQ +Y AMEF+ GGD + N + L A+FY +E+
Sbjct: 875 VFLLATKTKHPFLTNLYCSFQTENRIYFAMEFIGGGDLMWHVQNQR-LSVRRAKFYAAEV 933
Query: 280 FCAVNALHQLGYTHRDLKPENFLIDSKGHIKLTDFGLASGTVSMERIESMKIRLQEVKNL 339
A+ H G +RDLK EN L+ +GHIK+ D+GL
Sbjct: 934 LLALKYFHDNGVIYRDLKLENILLTPEGHIKIADYGLC---------------------- 971
Query: 340 EFPEFRERSMDDRRRMYNKLREEEVRYAHST---VGSPDYMALEVLEAKNYDFTVDYWSL 396
++E+ Y + T G+P++MA E+L+ + Y VD+W+
Sbjct: 972 ---------------------KDEMWYGNRTSTFCGTPEFMAPEILKEQEYTKAVDWWAF 1010
Query: 397 GCILFESLVGYTPFSGNSTNETYENLRNWKHVLQRPKCDNGRYAFSDRTWELIT----RL 452
G +L++ L+ +PFSG+ +E + + D Y D E++ L
Sbjct: 1011 GVLLYQMLLCQSPFSGDDEDEVFNAILT----------DEPLYPI-DMAGEIVQIFQGLL 1059
Query: 453 IADPINRL----KSFEHVKRMRYFSEIDFNTLRT--IHPPFIPQLDNEEDVGYFD-DFTN 505
DP RL + + V +F I+F+ + + PP+IP++ + ED YF+ +FT+
Sbjct: 1060 TKDPEKRLGAGPRDADEVMEEPFFRNINFDDILNLRVKPPYIPEIKSPEDTSYFEQEFTS 1119
>Hs5453978 [T] KOG0614 cGMP-dependent protein kinase
Length = 762
Score = 117 bits (294), Expect = 4e-26
Identities = 84/302 (27%), Positives = 145/302 (47%), Gaps = 54/302 (17%)
Query: 215 DHVLTERDILTTTRSEWLVKLLYAFQDPQSLYLAMEFVPGGDFRTLLLNTKFLQAPHARF 274
+HV +E+ IL S ++VKL F+D + +Y+ +E GG+ ++L + P ++F
Sbjct: 496 EHVYSEKRILEELCSPFIVKLYRTFKDNKYVYMLLEACLGGELWSILRDRGSFDEPTSKF 555
Query: 275 YISEMFCAVNALHQLGYTHRDLKPENFLIDSKGHIKLTDFGLASGTVSMERIESMKIRLQ 334
++ + A + LH+LG +RDLKPEN ++D++G++KL DFG A S ++
Sbjct: 556 CVACVTEAFDYLHRLGIIYRDLKPENLILDAEGYLKLVDFGFAKKIGSGQK--------- 606
Query: 335 EVKNLEFPEFRERSMDDRRRMYNKLREEEVRYAHSTVGSPDYMALEVLEAKNYDFTVDYW 394
+ G+P+Y+A EV+ K +DF+VD+W
Sbjct: 607 --------------------------------TWTFCGTPEYVAPEVILNKGHDFSVDFW 634
Query: 395 SLGCILFESLVGYTPFSGNSTNETYENLRNWKHVLQRPKCDNGRYAFSDRTWELITRLI- 453
SLG +++E L G PFSG TY + + P+ + R +LI RL
Sbjct: 635 SLGILVYELLTGNPPFSGVDQMMTYNLILKGIEKMDFPR------KITRRPEDLIRRLCR 688
Query: 454 ADPINRLKSFEH----VKRMRYFSEIDFNTL--RTIHPPFIPQLDNEEDVGYFDDFTNEE 507
+P RL + ++ +K+ R+ + ++ L R++ P +L D YFD + E+
Sbjct: 689 QNPTERLGNLKNGINDIKKHRWLNGFNWEGLKARSLPSPLQRELKGPIDHSYFDKYPPEK 748
Query: 508 HM 509
M
Sbjct: 749 GM 750
>CE05507 [T] KOG0603 Ribosomal protein S6 kinase
Length = 785
Score = 117 bits (293), Expect = 5e-26
Identities = 85/298 (28%), Positives = 141/298 (46%), Gaps = 46/298 (15%)
Query: 215 DHVLTERDILTTTR-SEWLVKLLYAFQDPQSLYLAMEFVPGGDFRTLLLNTKFLQAPHAR 273
+H + ER +L R + +LV L YAFQ L++ ME+V GG+ T L + AR
Sbjct: 64 EHTMAERQVLERLRGTPFLVNLFYAFQTDTKLHIVMEYVRGGELFTHLCSRGHFDLEAAR 123
Query: 274 FYISEMFCAVNALHQLGYTHRDLKPENFLIDSKGHIKLTDFGLASGTVSMERIESMKIRL 333
F I+E+ A+++LHQ +RDLK EN L+D +GH+KLTDFGL+
Sbjct: 124 FVIAELVVAIDSLHQRKVIYRDLKLENILLDEEGHVKLTDFGLS---------------- 167
Query: 334 QEVKNLEFPEFRERSMDDRRRMYNKLREEEVRYAHSTVGSPDYMALEVLEAK--NYDFTV 391
L P E+ A+S G+ +YM+ EV+ Y V
Sbjct: 168 ----KLFLP-------------------GELDRANSYCGTIEYMSPEVINRPEGGYSDVV 204
Query: 392 DYWSLGCILFESLVGYTPFSGNSTNETYENLRNWKHVLQRPKCDNGRYAFSDRTWELITR 451
D+WSLG I FE L G +PF+ + + +++ + P D +L+ +
Sbjct: 205 DWWSLGVISFELLTGCSPFTVDGAQNSSKDIAKRIMTKKVPFPKTMDVDARDFIGQLLEK 264
Query: 452 LIADPINRLKSFEHVKRMRYFSEIDFNTL--RTIHPPFIPQLDNEEDVGYFD-DFTNE 506
+ + + +K ++ S ID++ RT+ P +P++ ++ D +F +FT++
Sbjct: 265 KLEKRLG-YNGVDEIKNHKFMSSIDWDAAVKRTLKPVIVPRIGHDLDTQFFSAEFTSQ 321
Score = 79.3 bits (194), Expect = 1e-14
Identities = 79/280 (28%), Positives = 115/280 (40%), Gaps = 45/280 (16%)
Query: 232 LVKLLYAFQDPQSLYLAMEFVPGGDFRTLLLNTKFLQAPHARFYISEMFCAVNALHQLGY 291
+V+L DP YL ME + G + + + A + ++ AV LH
Sbjct: 437 IVQLHDVHSDPLHFYLVMEILTGNELLERIRKLERFTESEAADIMRQLVSAVKYLHDKRI 496
Query: 292 THRDLKPENFL---IDSKGHIKLTDFGLASGTVSMERIESMKIRLQEVKNLEFPEFRERS 348
HRDLKPEN L IDS ++L DFG A + SM+ +L+ V+ L
Sbjct: 497 VHRDLKPENILFESIDSSARLRLVDFGFARLLPN-----SMEQQLKSVQVL--------- 542
Query: 349 MDDRRRMYNKLREEEVRYAHSTVGSPDYMALEVLEA----KNYDFTVDYWSLGCILFESL 404
R+MY + ++ + + Y A EVL+ Y+ D WSLG +LF L
Sbjct: 543 ----RKMYGLIAHNHSLHSETPCFTLQYAAPEVLDVGDSQPEYNEQCDLWSLGVVLFTML 598
Query: 405 VGYTPFSGNSTNETYENLRNWKHVLQRPKCDNGRYAFSDRTW--------ELITRLI-AD 455
G PF S E+ ++QR ++F+ W LIT L+ D
Sbjct: 599 SGQVPFHARSRQESA------TEIMQR--ICRAEFSFTGDAWTNVSADAKNLITGLLTVD 650
Query: 456 PINRLKSFEHVKRMRYFSEIDFNT-LRTIHPPFIPQLDNE 494
P RL E M S +T L+T P +P +E
Sbjct: 651 PKKRLSMQELTAHMWLKSSASMDTPLQT--PSILPSSADE 688
>Hs4759052 [T] KOG0603 Ribosomal protein S6 kinase
Length = 809
Score = 117 bits (292), Expect = 6e-26
Identities = 90/304 (29%), Positives = 145/304 (47%), Gaps = 58/304 (19%)
Query: 214 TDHVLTERDILTTTR-SEWLVKLLYAFQDPQSLYLAMEFVPGGDFRTLLLNTKFLQAPHA 272
T+H TER +L R S +LV L YAFQ L+L ++++ GG+ T L +
Sbjct: 95 TEHTRTERQVLEHIRQSPFLVTLHYAFQTETKLHLILDYINGGELFTHLSQRERFTEHEV 154
Query: 273 RFYISEMFCAVNALHQLGYTHRDLKPENFLIDSKGHIKLTDFGLASGTVSMERIESMKIR 332
+ Y+ E+ A+ LH+LG +RD+K EN L+DS GH+ LTDFGL+ V+
Sbjct: 155 QIYVGEIVLALEHLHKLGIIYRDIKLENILLDSNGHVVLTDFGLSKEFVA---------- 204
Query: 333 LQEVKNLEFPEFRERSMDDRRRMYNKLREEEVRYAHSTVGSPDYMALEVLEA--KNYDFT 390
+E A+S G+ +YMA +++ +D
Sbjct: 205 -----------------------------DETERAYSFCGTIEYMAPDIVRGGDSGHDKA 235
Query: 391 VDYWSLGCILFESLVGYTPFS--GNSTNETYENLRNWKHVLQRPKCDNGRYAFSDRTWEL 448
VD+WSLG +++E L G +PF+ G ++ + R K P+ S +L
Sbjct: 236 VDWWSLGVLMYELLTGASPFTVDGEKNSQAEISRRILKSEPPYPQ------EMSALAKDL 289
Query: 449 ITRLI-ADPINRL----KSFEHVKRMRYFSEIDFNTL--RTIHPPFIPQLDNEEDVGYF- 500
I RL+ DP RL + + +K +F +I+++ L + + PF P + +E DV F
Sbjct: 290 IQRLLMKDPKKRLGCGPRDADEIKEHLFFQKINWDDLAAKKVPAPFKPVIRDELDVSNFA 349
Query: 501 DDFT 504
++FT
Sbjct: 350 EEFT 353
Score = 77.0 bits (188), Expect = 7e-14
Identities = 62/242 (25%), Positives = 97/242 (39%), Gaps = 48/242 (19%)
Query: 232 LVKLLYAFQDPQSLYLAMEFVPGGDFRTLLLNTKFLQAPHARFYISEMFCAVNALHQLGY 291
+VKL F D +L ME + GG+ L K A + + ++ A++ +H LG
Sbjct: 481 IVKLHEVFHDQLHTFLVMELLNGGELFDALRKKKHFSETEASYIMRKLVSALSHMHDLGV 540
Query: 292 THRDLKPENFLIDSKG---HIKLTDFGLASGTVSMERIESMKIRLQEVKNLEFPEFRERS 348
HRDLKPEN L + IK+ DFG A +++ + + L+ P F S
Sbjct: 541 VHRDLKPENLLFTDENDNLEIKIIDFGFA------------RLKPPDNQPLKTPCFTLHS 588
Query: 349 MDDRRRMYNKLREEEVRYAHSTVGSPDYMALEVLEAKNYDFTVDYWSLGCILFESLVGYT 408
E+L YD + D WSLG IL+ L G
Sbjct: 589 CRP----------------------------ELLNQNGYDESCDLWSLGVILYTMLSGQV 620
Query: 409 PFSGNSTNETYENLRNWKHVLQRPKCDNGRYAFSDRTWELITRLIADPINRLKSFEHVKR 468
PF + + T + V K G ++F W+ +++ D I L + + KR
Sbjct: 621 PFQSHDRSLTCTSA-----VEIMKKIKKGDFSFEGEAWKNVSQEAKDLIQGLLTVDPNKR 675
Query: 469 MR 470
++
Sbjct: 676 LK 677
>Hs4885061 [T] KOG0690 Serine/threonine protein kinase
Length = 480
Score = 116 bits (291), Expect = 8e-26
Identities = 92/349 (26%), Positives = 148/349 (42%), Gaps = 60/349 (17%)
Query: 166 KPKHK----DFEMITXXXXXXXXXXXLARKKDTKEICAXXXXXXXXXXXXEGTDHVLTER 221
KPKH+ +FE + L ++K T A + H LTE
Sbjct: 140 KPKHRVTMNEFEYLKLLGKGTFGKVILVKEKATGRYYAMKILKKEVIVAKDEVAHTLTEN 199
Query: 222 DILTTTRSEWLVKLLYAFQDPQSLYLAMEFVPGGDFRTLLLNTKFLQAPHARFYISEMFC 281
+L +R +L L Y+FQ L ME+ GG+ L + ARFY +E+
Sbjct: 200 RVLQNSRHPFLTALKYSFQTHDRLCFVMEYANGGELFFHLSRERVFSEDRARFYGAEIVS 259
Query: 282 AVNALH-QLGYTHRDLKPENFLIDSKGHIKLTDFGLASGTVSMERIESMKIRLQEVKNLE 340
A++ LH + +RDLK EN ++D GHIK+TDFGL
Sbjct: 260 ALDYLHSEKNVVYRDLKLENLMLDKDGHIKITDFGLC----------------------- 296
Query: 341 FPEFRERSMDDRRRMYNKLREEEVRYAHSTVGSPDYMALEVLEAKNYDFTVDYWSLGCIL 400
+ + D M + G+P+Y+A EVLE +Y VD+W LG ++
Sbjct: 297 -----KEGIKDGATM------------KTFCGTPEYLAPEVLEDNDYGRAVDWWGLGVVM 339
Query: 401 FESLVGYTPFSGNSTNETYENLRNWKHVLQRPKCDNGRYAFSDRTWELITRLI-ADPINR 459
+E + G PF + +E + ++ P+ L++ L+ DP R
Sbjct: 340 YEMMCGRLPFYNQDHEKLFELI--LMEEIRFPR------TLGPEAKSLLSGLLKKDPKQR 391
Query: 460 L----KSFEHVKRMRYFSEIDFNTL--RTIHPPFIPQLDNEEDVGYFDD 502
L + + + + R+F+ I + + + + PPF PQ+ +E D YFD+
Sbjct: 392 LGGGSEDAKEIMQHRFFAGIVWQHVYEKKLSPPFKPQVTSETDTRYFDE 440
>Hs4885347 [T] KOG0986 G protein-coupled receptor kinase
Length = 500
Score = 115 bits (289), Expect = 1e-25
Identities = 95/324 (29%), Positives = 145/324 (44%), Gaps = 70/324 (21%)
Query: 212 EGTDHVLTERDILTTTRSEWLVKLLYAFQDPQSLYLAMEFVPGGD--FRTLLLNTKFLQA 269
+G L E+ IL +S ++V L YA++ +L L + + GGD F L
Sbjct: 195 KGEAMALNEKRILEKVQSRFVVSLAYAYETKDALCLVLTIMNGGDLKFHIYNLGNPGFDE 254
Query: 270 PHARFYISEMFCAVNALHQLGYTHRDLKPENFLIDSKGHIKLTDFGLASGTVSMERIESM 329
A FY +E+ C + L + +RDLKPEN L+D +GHI+++D GLA+
Sbjct: 255 QRAVFYAAELCCGLEDLQRERIVYRDLKPENILLDDRGHIRISDLGLAT----------- 303
Query: 330 KIRLQEVKNLEFPEFRERSMDDRRRMYNKLREEEVRYAHSTVGSPDYMALEVLEAKNYDF 389
E PE + VR TVG YMA EV+ + Y F
Sbjct: 304 ----------EIPE-----------------GQRVRGRVGTVG---YMAPEVVNNEKYTF 333
Query: 390 TVDYWSLGCILFESLVGYTPFSGNSTNETYENLRNWKHVLQRPKCDNGRYA--FSDRTWE 447
+ D+W LGC+++E + G++PF + Y+ W+ V QR K D Y+ FS+
Sbjct: 334 SPDWWGLGCLIYEMIQGHSPF------KKYKEKVKWEEVDQRIKNDTEEYSEKFSEDAKS 387
Query: 448 LITRLIA-DPINRL----KSFEHVKRMRYFSEIDFNTLRT--IHPPFIPQ---------L 491
+ L+ +P RL + VK+ F +I+F L + PPF P L
Sbjct: 388 ICRMLLTKNPSKRLGCRGEGAAGVKQHPVFKDINFRRLEANMLEPPFCPDPHAVYCKDVL 447
Query: 492 DNEE---DVGYFDDFTNEEHMARY 512
D E+ G + D +E+ AR+
Sbjct: 448 DIEQFSAVKGIYLDTADEDFYARF 471
>Hs10835065 [T] KOG0616 cAMP-dependent protein kinase catalytic subunit (PKA)
Length = 277
Score = 115 bits (289), Expect = 1e-25
Identities = 67/235 (28%), Positives = 108/235 (45%), Gaps = 43/235 (18%)
Query: 188 LARKKDTKEICAXXXXXXXXXXXXEGTDHVLTERDILTTTRSEWLVKLLYAFQDPQSLYL 247
L ++K K A + HV E+ +L +L++L + + + + LY+
Sbjct: 65 LVKEKTAKHFFALKVMSIPDVIRRKQEQHVHNEKSVLKEVSHPFLIRLFWTWHEERFLYM 124
Query: 248 AMEFVPGGDFRTLLLNTKFLQAPHARFYISEMFCAVNALHQLGYTHRDLKPENFLIDSKG 307
ME+VPGG+ + L N + FY +E+ CA+ LH +RDLKPEN L+D G
Sbjct: 125 LMEYVPGGELFSYLRNRGHFSSTTGLFYSAEIICAIEYLHSKEIVYRDLKPENILLDRDG 184
Query: 308 HIKLTDFGLASGTVSMERIESMKIRLQEVKNLEFPEFRERSMDDRRRMYNKLREEEVRYA 367
HIKLTDFG A + + DR
Sbjct: 185 HIKLTDFGFA-----------------------------KKLVDR--------------T 201
Query: 368 HSTVGSPDYMALEVLEAKNYDFTVDYWSLGCILFESLVGYTPFSGNSTNETYENL 422
+ G+P+Y+A EV+++K + VD+W+LG ++FE L G+ PF ++ Y+ +
Sbjct: 202 WTLCGTPEYLAPEVIQSKGHGRAVDWWALGILIFEMLSGFPPFFDDNPFGIYQKI 256
>CE17354 [T] KOG0694 Serine/threonine protein kinase
Length = 567
Score = 115 bits (288), Expect = 2e-25
Identities = 82/298 (27%), Positives = 137/298 (45%), Gaps = 55/298 (18%)
Query: 218 LTERDILTTTRSEWLVKLLYAFQDPQSLYLAMEFVPGGDFRTLLLNTKFLQAPHARFYIS 277
+ R ++ ++ +L +L +FQ + L+ ME++ GGD + K RFY
Sbjct: 285 IERRVLILASQCPFLCQLFCSFQTNEYLFFVMEYLNGGDLMHHIQQIKKFDEARTRFYAC 344
Query: 278 EMFCAVNALHQLGYTHRDLKPENFLIDSKGHIKLTDFGLASGTVSMERIESMKIRLQEVK 337
E+ A+ LH +RDLK +N L+D GHIKL DFG+A ++
Sbjct: 345 EIVVALQFLHTNNIIYRDLKLDNVLLDCDGHIKLADFGMAKTEMN--------------- 389
Query: 338 NLEFPEFRERSMDDRRRMYNKLREEEVRYAHSTVGSPDYMALEVLEAKNYDFTVDYWSLG 397
RE M A + G+PDY++ E+++ + Y+ VD+WS G
Sbjct: 390 -------RENGM-----------------ASTFCGTPDYISPEIIKGQLYNEAVDFWSFG 425
Query: 398 CILFESLVGYTPFSGNSTNETYENLRNWKHVLQRPKCDNGRYAFSDRTWELITRLI-ADP 456
+++E LVG +PF G +E ++++ N +RP S + ++ L +P
Sbjct: 426 VLMYEMLVGQSPFHGEGEDELFDSILN-----ERPYFPK---TISKEAAKCLSALFDRNP 477
Query: 457 INRLKSFE----HVKRMRYFSEIDFNTL--RTIHPPFIPQLDNEEDVGYF-DDFTNEE 507
RL E +++ +F +D+ R + PPF P + + D F DDFTNE+
Sbjct: 478 NTRLGMPECPDGPIRQHCFFRGVDWKRFENRQVPPPFKPNIKSNSDASNFDDDFTNEK 535
>CE17353 [T] KOG0694 Serine/threonine protein kinase
Length = 704
Score = 115 bits (288), Expect = 2e-25
Identities = 82/298 (27%), Positives = 137/298 (45%), Gaps = 55/298 (18%)
Query: 218 LTERDILTTTRSEWLVKLLYAFQDPQSLYLAMEFVPGGDFRTLLLNTKFLQAPHARFYIS 277
+ R ++ ++ +L +L +FQ + L+ ME++ GGD + K RFY
Sbjct: 422 IERRVLILASQCPFLCQLFCSFQTNEYLFFVMEYLNGGDLMHHIQQIKKFDEARTRFYAC 481
Query: 278 EMFCAVNALHQLGYTHRDLKPENFLIDSKGHIKLTDFGLASGTVSMERIESMKIRLQEVK 337
E+ A+ LH +RDLK +N L+D GHIKL DFG+A ++
Sbjct: 482 EIVVALQFLHTNNIIYRDLKLDNVLLDCDGHIKLADFGMAKTEMN--------------- 526
Query: 338 NLEFPEFRERSMDDRRRMYNKLREEEVRYAHSTVGSPDYMALEVLEAKNYDFTVDYWSLG 397
RE M A + G+PDY++ E+++ + Y+ VD+WS G
Sbjct: 527 -------RENGM-----------------ASTFCGTPDYISPEIIKGQLYNEAVDFWSFG 562
Query: 398 CILFESLVGYTPFSGNSTNETYENLRNWKHVLQRPKCDNGRYAFSDRTWELITRLI-ADP 456
+++E LVG +PF G +E ++++ N +RP S + ++ L +P
Sbjct: 563 VLMYEMLVGQSPFHGEGEDELFDSILN-----ERPYFPK---TISKEAAKCLSALFDRNP 614
Query: 457 INRLKSFE----HVKRMRYFSEIDFNTL--RTIHPPFIPQLDNEEDVGYF-DDFTNEE 507
RL E +++ +F +D+ R + PPF P + + D F DDFTNE+
Sbjct: 615 NTRLGMPECPDGPIRQHCFFRGVDWKRFENRQVPPPFKPNIKSNSDASNFDDDFTNEK 672
>At3g27580 [R] KOG0610 Putative serine/threonine protein kinase
Length = 578
Score = 115 bits (288), Expect = 2e-25
Identities = 90/311 (28%), Positives = 142/311 (44%), Gaps = 44/311 (14%)
Query: 219 TERDILTTTRSEWLVKLLYAFQDPQSLYLAMEFVPGGDFRTLLLNT--KFLQAPHARFYI 276
TE++IL + +L L F+ + L MEF PGGD +L K+ ARFY+
Sbjct: 229 TEKEILQSLDHPFLPTLYSHFETEMNSCLVMEFCPGGDLHSLRQKQRGKYFPEQAARFYV 288
Query: 277 SEMFCAVNALHQLGYTHRDLKPENFLIDSKGHIKLTDFGLA-SGTVSMERIESMKIRLQE 335
+E+ A+ LH LG +RDLKPEN L+ GHI L+DF L+ VS + I L+
Sbjct: 289 AEVLLAMEYLHMLGIIYRDLKPENVLVREDGHIMLSDFDLSLRCAVSPTLVRFAAITLES 348
Query: 336 VKN------------------------------LEFPEFRERSMDDRRR---MYNKLREE 362
+ L + R++S D R+ + + E
Sbjct: 349 KSSSYCIQPTCVDQSSCIVQPDCIQPVCFTPRFLSKGKHRKKSNDMSRQIRPLPELIAEP 408
Query: 363 EVRYAHSTVGSPDYMALEVLEAKNYDFTVDYWSLGCILFESLVGYTPFSGNSTNETYENL 422
+ S VG+ +Y+A E+++ + + VD+W+ G L+E L G TPF G T N+
Sbjct: 409 TSARSMSFVGTHEYLAPEIIKGEGHGSAVDWWTFGIFLYELLFGITPFRGGDNRATLFNV 468
Query: 423 RNWKHVLQRPKCDNGRYAFSDRTWELITRLIADPINRL---KSFEHVKRMRYFSEIDFNT 479
L+ P+ N +A D L L+ +P +RL + +K+ +F +++
Sbjct: 469 VG--QPLRFPEHPNVSFAARDLIRGL---LVKEPQHRLAYRRGATEIKQHPFFQSVNWAL 523
Query: 480 LRTIHPPFIPQ 490
+R PP IPQ
Sbjct: 524 IRCTSPPQIPQ 534
>At2g36350 [R] KOG0610 Putative serine/threonine protein kinase
Length = 949
Score = 115 bits (287), Expect = 2e-25
Identities = 94/326 (28%), Positives = 141/326 (42%), Gaps = 57/326 (17%)
Query: 214 TDHVLTERDILTTTRSEWLVKLLYAFQDPQSLYLAMEFVPGGDFRTLLLN--TKFLQAPH 271
T ER IL +L L F L ME+ PGGD L ++ P
Sbjct: 601 TPRAQAERAILKMLDHPFLPTLYAQFTSDNLSCLVMEYCPGGDLHVLRQKQLSRCFSEPA 660
Query: 272 ARFYISEMFCAVNALHQLGYTHRDLKPENFLIDSKGHIKLTDFGLA-------------- 317
RFY++E+ A+ LH LG +RDLKPEN L+ GHI LTDF L+
Sbjct: 661 TRFYVAEILLALEYLHMLGVIYRDLKPENILVREDGHIMLTDFDLSLRCAVNPTLLRSTS 720
Query: 318 ---------SGTVSME-------------------RIESMKIRLQEVKNLEFPEFRERSM 349
SG S R+ S + R Q+ + + P+ +
Sbjct: 721 PPEKDPARMSGPYSTSNCIQPLCIEPSCRVPCFSPRLLSTQARNQKPRKPKRPDLLTQQF 780
Query: 350 DDRRRMYNKLREEEVRYAHSTVGSPDYMALEVLEAKNYDFTVDYWSLGCILFESLVGYTP 409
R + + E ++S VG+ +Y+A E+++ + + VD+W+ G +L+E L G TP
Sbjct: 781 ---RSLPQLVAEPTEARSNSFVGTHEYLAPEIIKGEGHGAAVDWWTFGVLLYELLYGKTP 837
Query: 410 FSGNSTNETYENLRNWKHVLQRPKCDNGRYAFSDRTWELITR-LIADPINRL---KSFEH 465
F G ET N+ V Q K + S + ELI R L+ DP +RL K
Sbjct: 838 FKGYDNEETLSNV-----VYQNLKFPDSPLV-SFQAKELIRRLLVKDPESRLGSEKGAAE 891
Query: 466 VKRMRYFSEIDFNTLRTIHPPFIPQL 491
+KR +F +++ +R PP +P +
Sbjct: 892 IKRHPFFEGLNWALIRCAIPPELPDI 917
>CE02586 [T] KOG0696 Serine/threonine protein kinase
Length = 861
Score = 114 bits (286), Expect = 3e-25
Identities = 93/345 (26%), Positives = 140/345 (39%), Gaps = 59/345 (17%)
Query: 168 KHKDFEMITXXXXXXXXXXXLARKKDTKEICAXXXXXXXXXXXXEGTDHVLTERDILTTT 227
K DF +T L +K TKE+ A + + +TE+ +L
Sbjct: 409 KASDFNFLTVLGKGSFGKVLLGEQKTTKELFAIKVLKKDVIIQDDDVECTMTEKRVLALP 468
Query: 228 -RSEWLVKLLYAFQDPQSLYLAMEFVPGGDFRTLLLNTKFLQAPHARFYISEMFCAVNAL 286
+ +LV L FQ LY MEFV GGD + + P A FY +E+ + L
Sbjct: 469 EKPSFLVALHSCFQTMDRLYFVMEFVNGGDLMYQIQQVGKFKEPVAVFYAAEIAVGLFFL 528
Query: 287 HQLGYTHRDLKPENFLIDSKGHIKLTDFGLASGTVSMERIESMKIRLQEVKNLEFPEFRE 346
H G +RDLK +N +++ GHIK+TDFG+ +E
Sbjct: 529 HSKGIIYRDLKLDNVMLERDGHIKITDFGMC---------------------------KE 561
Query: 347 RSMDDRRRMYNKLREEEVRYAHSTVGSPDYMALEVLEAKNYDFTVDYWSLGCILFESLVG 406
D + G+PDY+A E++ + Y +VD+W+ G +LFE L G
Sbjct: 562 NIFGDAT-------------TKTFCGTPDYIAPEIILYQPYGKSVDWWAYGVLLFEMLAG 608
Query: 407 YTPFSGNSTNETYENLRNWKHVLQRPKCDNGRYAFSDRTWELI-TRLIADPINRL----- 460
PF G +E + + +H + PK + S L LI +P RL
Sbjct: 609 QPPFDGEDEDELFTAIT--EHNVSYPK------SLSKEAVSLCKALLIKNPSKRLGCTGD 660
Query: 461 --KSFEHVKRMRYFSEIDFNTLRT--IHPPFIPQLDNEEDVGYFD 501
+ +K +F ID+ + T I PPF P+L + FD
Sbjct: 661 DESASRDIKEHPFFRRIDWFKIETRQIQPPFKPKLKTDRSTENFD 705
>7303915 [T] KOG0694 Serine/threonine protein kinase
Length = 590
Score = 114 bits (286), Expect = 3e-25
Identities = 89/296 (30%), Positives = 137/296 (46%), Gaps = 61/296 (20%)
Query: 222 DILTTTRSEWLVKLLYAFQDPQSLYLAMEFVPGGDFRTLLLNTKFLQAPHARFYISEMFC 281
++ R +LV L FQ Q + ME+ GGD + FL+ P A FY + +
Sbjct: 316 EVANAMRHPFLVNLYSCFQTEQHVCFVMEYAAGGDLMMHIHTDVFLE-PRAVFYAACVVL 374
Query: 282 AVNALHQLGYTHRDLKPENFLIDSKGHIKLTDFGLASGTVSMERIESMKIRLQEVKNLEF 341
+ LH+ +RDLK +N L+D++G++K+ DFGL E M
Sbjct: 375 GLQYLHENKIIYRDLKLDNLLLDTEGYVKIADFGLCK--------EGM------------ 414
Query: 342 PEFRERSMDDRRRMYNKLREEEVRYAHSTVGSPDYMALEVLEAKNYDFTVDYWSLGCILF 401
DR + G+P+++A EVL +Y VD+W LG ++F
Sbjct: 415 ------GFGDRTGTF--------------CGTPEFLAPEVLTETSYTRAVDWWGLGVLIF 454
Query: 402 ESLVGYTPFSGNSTNETYENLRNWKHVLQRPKCDNGRYA--FSDRTWELITRLI-ADPIN 458
E LVG +PF G+ E ++++ N D RY S ++ RL+ +P
Sbjct: 455 EMLVGESPFPGDDEEEVFDSIVN----------DEVRYPRFLSLEAIAVMRRLLRKNPER 504
Query: 459 RLKSFEH----VKRMRYFSEI--DFNTLRTIHPPFIPQLDNEEDVGYFD-DFTNEE 507
RL S E VK+ +F I D LR + PPF+P +++ EDV FD +FT+E+
Sbjct: 505 RLGSSERDAEDVKKQAFFRSIVWDDLLLRKVKPPFVPTINHLEDVSNFDEEFTSEK 560
>7303914 [T] KOG0694 Serine/threonine protein kinase
Length = 1284
Score = 114 bits (286), Expect = 3e-25
Identities = 89/296 (30%), Positives = 137/296 (46%), Gaps = 61/296 (20%)
Query: 222 DILTTTRSEWLVKLLYAFQDPQSLYLAMEFVPGGDFRTLLLNTKFLQAPHARFYISEMFC 281
++ R +LV L FQ Q + ME+ GGD + FL+ P A FY + +
Sbjct: 1010 EVANAMRHPFLVNLYSCFQTEQHVCFVMEYAAGGDLMMHIHTDVFLE-PRAVFYAACVVL 1068
Query: 282 AVNALHQLGYTHRDLKPENFLIDSKGHIKLTDFGLASGTVSMERIESMKIRLQEVKNLEF 341
+ LH+ +RDLK +N L+D++G++K+ DFGL E M
Sbjct: 1069 GLQYLHENKIIYRDLKLDNLLLDTEGYVKIADFGLCK--------EGM------------ 1108
Query: 342 PEFRERSMDDRRRMYNKLREEEVRYAHSTVGSPDYMALEVLEAKNYDFTVDYWSLGCILF 401
DR + G+P+++A EVL +Y VD+W LG ++F
Sbjct: 1109 ------GFGDRTGTF--------------CGTPEFLAPEVLTETSYTRAVDWWGLGVLIF 1148
Query: 402 ESLVGYTPFSGNSTNETYENLRNWKHVLQRPKCDNGRYA--FSDRTWELITRLI-ADPIN 458
E LVG +PF G+ E ++++ N D RY S ++ RL+ +P
Sbjct: 1149 EMLVGESPFPGDDEEEVFDSIVN----------DEVRYPRFLSLEAIAVMRRLLRKNPER 1198
Query: 459 RLKSFEH----VKRMRYFSEI--DFNTLRTIHPPFIPQLDNEEDVGYFD-DFTNEE 507
RL S E VK+ +F I D LR + PPF+P +++ EDV FD +FT+E+
Sbjct: 1199 RLGSSERDAEDVKKQAFFRSIVWDDLLLRKVKPPFVPTINHLEDVSNFDEEFTSEK 1254
>At2g44830 [R] KOG0610 Putative serine/threonine protein kinase
Length = 762
Score = 114 bits (285), Expect = 4e-25
Identities = 134/536 (25%), Positives = 209/536 (38%), Gaps = 79/536 (14%)
Query: 29 AKVMLDPPSTPTRIRGSPSPTRSIVKNPENSLMDIDDDTQGDLTADITKSPKKLPKD--- 85
A+ +++ P+T SP +N ENSL+ D D + A + S P
Sbjct: 201 AESIVEEPATSL----SPFSVARASQNTENSLLPPDSDKECVWDASLPPSTNVSPHSSSV 256
Query: 86 ----------FYKKSSKT----KSKRLVSVCQMYF---LDYYCDMFDYVISRRERTRQVI 128
SS T +S ++S+ + YF + D F+ + R
Sbjct: 257 ESMNLARAMSIANSSSATSTTQRSDVVLSMDKNYFDRSISMVLDSFESTKTSASRASDSS 316
Query: 129 NYLEEQRRSNLMGTEQITNE-----WQGYLTKETNILRKRRLKPKHKDFEMITXXXXXXX 183
EE SN G+ ++ W L T R L H F+++
Sbjct: 317 GLSEESSWSNFTGSLNKPHKGNDPWWNAILAIRT---RDGILGMSH--FKLLKRLGCGDI 371
Query: 184 XXXXLARKKDTKEICAXXXXXXXXXXXXEGTDHVLTERDILTTTRSEWLVKLLYAFQDPQ 243
LA T+ A + + TERDIL +L L F+ +
Sbjct: 372 GSVYLAELSGTRCHFAVKVMDKASLEDRKKLNRAQTERDILQLLDHPFLPTLYTHFETDR 431
Query: 244 SLYLAMEFVPGGDFRTLLLNT--KFLQAPHARFYISEMFCAVNALHQLGYTHRDLKPENF 301
L ME+ PGGD TL K ARFY +E+ A+ LH LG +RDLKPEN
Sbjct: 432 FSCLVMEYCPGGDLHTLRQRQPGKHFSEYAARFYAAEVLLALEYLHMLGVVYRDLKPENV 491
Query: 302 LIDSKGHIKLTDFGLA-SGTVSMERIESMK---------------IRLQEVKNLEFPEFR 345
L+ GHI L+DF L+ VS I++ + ++ F
Sbjct: 492 LVRDDGHIMLSDFDLSLRCAVSPTLIKTFDSDPSRRGAFCVQPACMEPTSACIIQPSCFL 551
Query: 346 ERSMDDRRRMYNKLREEEVRY------------------AHSTVGSPDYMALEVLEAKNY 387
RS+ + NK R+ + + + S VG+ +Y+A E+++ + +
Sbjct: 552 PRSIFPNKNKKNKSRKTQADFFKSHSGSLPELVAEPNTRSMSFVGTHEYLAPEIIKGEGH 611
Query: 388 DFTVDYWSLGCILFESLVGYTPFSGNSTNETYENLRNWKHVLQRPKCDNGRYAFSDRTWE 447
VD+W+ G + E L G TPF G+ T N+ L+ P+ YA D
Sbjct: 612 GSAVDWWTFGIFVHELLYGKTPFKGSGNRATLFNVVG--EQLKFPESPATSYAGRDLIQA 669
Query: 448 LITRLIADPINRL---KSFEHVKRMRYFSEIDFNTLRTIHPPFIP-QLDNEEDVGY 499
L L+ DP NRL + +K+ +F +++ +R PP +P Q++ E Y
Sbjct: 670 L---LVKDPKNRLGTKRGATEIKQHPFFEGVNWALIRCSTPPEVPRQMETEPPPKY 722
>7302861 [T] KOG0696 Serine/threonine protein kinase
Length = 700
Score = 114 bits (285), Expect = 4e-25
Identities = 94/379 (24%), Positives = 155/379 (40%), Gaps = 66/379 (17%)
Query: 171 DFEMITXXXXXXXXXXXLARKKDTKEICAXXXXXXXXXXXXEGTDHVLTERDILTTT-RS 229
DF + LA ++ T E+ A + + + E+ IL + R
Sbjct: 370 DFNFVKVIGKGSFGKVLLAERRGTDELYAVKVLRKDVIIQTDDMELPMNEKKILALSGRP 429
Query: 230 EWLVKLLYAFQDPQSLYLAMEFVPGGDFRTLLLNTKFLQAPHARFYISEMFCAVNALHQL 289
+LV + FQ L+ ME+ GGD + + A FY E+ A+ LH+
Sbjct: 430 PFLVSMHSCFQTMDRLFFVMEYCKGGDLMYHMQQYGRFKESVAIFYAVEVAIALFFLHER 489
Query: 290 GYTHRDLKPENFLIDSKGHIKLTDFGLASGTVSMERIESMKIRLQEVKNLEFPEFRERSM 349
+RDLK +N L+D +GH+KL DFGL+ V+
Sbjct: 490 DIIYRDLKLDNILLDGEGHVKLVDFGLSKEGVT--------------------------- 522
Query: 350 DDRRRMYNKLREEEVRYAHSTVGSPDYMALEVLEAKNYDFTVDYWSLGCILFESLVGYTP 409
E + + G+P+YMA E++ Y D+WS G +LFE + G P
Sbjct: 523 -------------ERQTTRTFCGTPNYMAPEIVSYDPYSIAADWWSFGVLLFEFMAGQAP 569
Query: 410 FSGNSTNETYENLRNWKHVLQRPKCDNGRYAFSDRTWELITR-LIADPINRLKSFEHVKR 468
F G+ + N+++ K V + FS ++IT L P NRL + + ++
Sbjct: 570 FEGDDETTVFRNIKDKKAVFPK--------HFSVEAMDIITSFLTKKPNNRLGAGRYARQ 621
Query: 469 ----MRYFSEIDFNTLRT--IHPPFIPQLDNEEDVGYFDD-FTNEEHMARYVDVFKRQDR 521
+F +D++ + PP P + + +D+ FDD FT E+ D+
Sbjct: 622 EITTHPFFRNVDWDKAEACEMEPPIKPMIKHRKDISNFDDAFTKEK------TDLTPTDK 675
Query: 522 LTAMVDDSLSDSKLVGFTF 540
L M +L + +GF+F
Sbjct: 676 LFMM---NLDQNDFIGFSF 691
>YDR490c [T] KOG0592 3-phosphoinositide-dependent protein kinase (PDK1)
Length = 766
Score = 114 bits (284), Expect = 5e-25
Identities = 88/323 (27%), Positives = 143/323 (44%), Gaps = 38/323 (11%)
Query: 157 TNILRKRRLKPKHKDFEMITXXXXXXXXXXXLARKKDTKEICAXXXXXXXXXXXXEGTDH 216
T L K +K KDF+ LA +D+ + A + +
Sbjct: 110 TGELTKHVVKMGIKDFKFGEQLGDGSYSSVVLATARDSGKKYAVKVLSKEYLIRQKKVKY 169
Query: 217 VLTERDILTTTR-SEWLVKLLYAFQDPQSLYLAMEFVPGGDFRTLLLNTKFLQAPHARFY 275
V E+ L ++ + KL + FQD SLY +E+ P GDF L+ L AR+Y
Sbjct: 170 VTVEKLALQKLNGTKGIFKLFFTFQDEASLYFLLEYAPHGDFLGLIKKYGSLNETCARYY 229
Query: 276 ISEMFCAVNALHQLGYTHRDLKPENFLIDSKGHIKLTDFGLASGTVSMERIESMKIRLQE 335
S++ AV++LH +G HRD+KPEN L+D +KLTDFG A KI +E
Sbjct: 230 ASQIIDAVDSLHNIGIIHRDIKPENILLDKNMKVKLTDFGTA------------KILPEE 277
Query: 336 VKNLEFPEFRERSMDDRRRMYNKLREEEVRYAHSTVGSPDYMALEVLEAKNYDFTVDYWS 395
N D + ++ + + S VG+ +Y++ E+L D D W+
Sbjct: 278 PSNTA----------DGKPYFDLYAKSK-----SFVGTAEYVSPELLNDNYTDSRCDIWA 322
Query: 396 LGCILFESLVGYTPFSGNSTNETYENLRNWKHVLQRPKCDNGRYAFSDRTWELITR-LIA 454
GCIL++ L G PF + T++ + ++ F +L+ + L+
Sbjct: 323 FGCILYQMLAGKPPFKAANEYLTFQKVMKIQYAFTA--------GFPQIVKDLVKKLLVR 374
Query: 455 DPINRLKSFEHVKRMRYFSEIDF 477
DP +RL + + +K +F E++F
Sbjct: 375 DPNDRL-TIKQIKAHLFFHEVNF 396
>Hs4506073 [T] KOG0694 Serine/threonine protein kinase
Length = 942
Score = 112 bits (281), Expect = 1e-24
Identities = 94/350 (26%), Positives = 151/350 (42%), Gaps = 64/350 (18%)
Query: 170 KDFEMITXXXXXXXXXXXLARKKDTKEICAXXXXXXXXXXXXEGTDHVLTERDILTTTRS 229
+DF+ + L+ + + E+ A + + ++ E+ IL S
Sbjct: 613 EDFKFLAVLGRGHFGKVLLSEFRPSGELFAIKALKKGDIVARDEVESLMCEKRILAAVTS 672
Query: 230 E---WLVKLLYAFQDPQSLYLAMEFVPGGDFRTLLLNTKFLQAPHARFYISEMFCAVNAL 286
+LV L FQ P+ + ME+ GGD L +++ P A FY + + + L
Sbjct: 673 AGHPFLVNLFGCFQTPEHVCFVMEYSAGGDLM-LHIHSDVFSEPRAIFYSACVVLGLQFL 731
Query: 287 HQLGYTHRDLKPENFLIDSKGHIKLTDFGLASGTVSMERIESMKIRLQEVKNLEFPEFRE 346
H+ +RDLK +N L+D++G++K+ DFGL E M
Sbjct: 732 HEHKIVYRDLKLDNLLLDTEGYVKIADFGLCK--------EGM----------------- 766
Query: 347 RSMDDRRRMYNKLREEEVRYAHSTVGSPDYMALEVLEAKNYDFTVDYWSLGCILFESLVG 406
DR + G+P+++A EVL +Y VD+W LG +L+E LVG
Sbjct: 767 -GYGDRTSTF--------------CGTPEFLAPEVLTDTSYTRAVDWWGLGVLLYEMLVG 811
Query: 407 YTPFSGNSTNETYENLRNWKHVLQRPKCDNGRYA--FSDRTWELITRLI-ADPINRLKSF 463
+PF G+ E ++++ N D RY S ++ RL+ +P RL S
Sbjct: 812 ESPFPGDDEEEVFDSIVN----------DEVRYPRFLSAEAIGIMRRLLRRNPERRLGSS 861
Query: 464 EH----VKRMRYFSEIDFNTL--RTIHPPFIPQLDNEEDVGYFD-DFTNE 506
E VK+ +F + + L R + PPF+P L DV FD +FT E
Sbjct: 862 ERDAEDVKKQPFFRTLGWEALLARRLPPPFVPTLSGRTDVSNFDEEFTGE 911
>Hs14758219 [T] KOG0694 Serine/threonine protein kinase
Length = 942
Score = 112 bits (281), Expect = 1e-24
Identities = 94/350 (26%), Positives = 151/350 (42%), Gaps = 64/350 (18%)
Query: 170 KDFEMITXXXXXXXXXXXLARKKDTKEICAXXXXXXXXXXXXEGTDHVLTERDILTTTRS 229
+DF+ + L+ + + E+ A + + ++ E+ IL S
Sbjct: 613 EDFKFLAVLGRGHFGKVLLSEFRPSGELFAIKALKKGDIVARDEVESLMCEKRILAAVTS 672
Query: 230 E---WLVKLLYAFQDPQSLYLAMEFVPGGDFRTLLLNTKFLQAPHARFYISEMFCAVNAL 286
+LV L FQ P+ + ME+ GGD L +++ P A FY + + + L
Sbjct: 673 AGHPFLVNLFGCFQTPEHVCFVMEYSAGGDLM-LHIHSDVFSEPRAIFYSACVVLGLQFL 731
Query: 287 HQLGYTHRDLKPENFLIDSKGHIKLTDFGLASGTVSMERIESMKIRLQEVKNLEFPEFRE 346
H+ +RDLK +N L+D++G++K+ DFGL E M
Sbjct: 732 HEHKIVYRDLKLDNLLLDTEGYVKIADFGLCK--------EGM----------------- 766
Query: 347 RSMDDRRRMYNKLREEEVRYAHSTVGSPDYMALEVLEAKNYDFTVDYWSLGCILFESLVG 406
DR + G+P+++A EVL +Y VD+W LG +L+E LVG
Sbjct: 767 -GYGDRTSTF--------------CGTPEFLAPEVLTDTSYTRAVDWWGLGVLLYEMLVG 811
Query: 407 YTPFSGNSTNETYENLRNWKHVLQRPKCDNGRYA--FSDRTWELITRLI-ADPINRLKSF 463
+PF G+ E ++++ N D RY S ++ RL+ +P RL S
Sbjct: 812 ESPFPGDDEEEVFDSIVN----------DEVRYPRFLSAEAIGIMRRLLRRNPERRLGSS 861
Query: 464 EH----VKRMRYFSEIDFNTL--RTIHPPFIPQLDNEEDVGYFD-DFTNE 506
E VK+ +F + + L R + PPF+P L DV FD +FT E
Sbjct: 862 ERDAEDVKKQPFFRTLGWEALLARRLPPPFVPTLSGRTDVSNFDEEFTGE 911
>7302860 [T] KOG0696 Serine/threonine protein kinase
Length = 679
Score = 112 bits (281), Expect = 1e-24
Identities = 98/379 (25%), Positives = 160/379 (41%), Gaps = 66/379 (17%)
Query: 171 DFEMITXXXXXXXXXXXLARKKDTKEICAXXXXXXXXXXXXEGTDHVLTERDILTT-TRS 229
DF I LA +K ++E+ A + + + E+ +L +
Sbjct: 349 DFNFIKVLGKGSFGKVLLAERKGSEELYAIKILKKDVIIQDDDVECTMIEKRVLALGEKP 408
Query: 230 EWLVKLLYAFQDPQSLYLAMEFVPGGDFRTLLLNTKFLQAPHARFYISEMFCAVNALHQL 289
+LV+L FQ L+ ME+V GGD + + P A FY +E+ + LH
Sbjct: 409 PFLVQLHSCFQTMDRLFFVMEYVNGGDLMFQIQQFGKFKEPVAVFYAAEIAAGLFFLHTK 468
Query: 290 GYTHRDLKPENFLIDSKGHIKLTDFGLASGTVSMERIESMKIRLQEVKNLEFPEFRERSM 349
G +RDLK +N L+D+ GH+K+ DFG+ +E +
Sbjct: 469 GILYRDLKLDNVLLDADGHVKIADFGMC---------------------------KENIV 501
Query: 350 DDRRRMYNKLREEEVRYAHSTVGSPDYMALEVLEAKNYDFTVDYWSLGCILFESLVGYTP 409
D+ + G+PDY+A E++ + Y +VD+W+ G +L+E LVG P
Sbjct: 502 GDKT-------------TKTFCGTPDYIAPEIILYQPYGKSVDWWAYGVLLYEMLVGQPP 548
Query: 410 FSGNSTNETYENLRNWKHVLQRPKCDNGRYAFSDRTWELITR-LIADPINRL----KSFE 464
F G E + + + H + PK + S E L P RL E
Sbjct: 549 FDGEDEEELFAAITD--HNVSYPK------SLSKEAKEACKGFLTKQPNKRLGCGSSGEE 600
Query: 465 HVKRMRYFSEIDFNTL--RTIHPPFIPQLDNEEDVGYFD-DFTNEEHMARYVDVFKRQDR 521
V+ +F ID+ + R + PPF P++ + +DV FD FT+E+ D+
Sbjct: 601 DVRLHPFFRRIDWEKIENREVQPPFKPKIKHRKDVSNFDKQFTSEK------TDLTPTDK 654
Query: 522 LTAMVDDSLSDSKLVGFTF 540
+ M +L S+ VGF++
Sbjct: 655 VFMM---NLDQSEFVGFSY 670
>Hs4885349 [T] KOG0986 G protein-coupled receptor kinase
Length = 590
Score = 112 bits (279), Expect = 2e-24
Identities = 84/287 (29%), Positives = 128/287 (44%), Gaps = 54/287 (18%)
Query: 212 EGTDHVLTERDILTTTRSEWLVKLLYAFQDPQSLYLAMEFVPGGDFRTLLLN--TKFLQA 269
+G L E+ IL S+++V L YA++ +L L + + GGD + + N +
Sbjct: 226 KGESMALNEKQILEKVNSQFVVNLAYAYETKDALCLVLTIMNGGDLKFHIYNMGNPGFEE 285
Query: 270 PHARFYISEMFCAVNALHQLGYTHRDLKPENFLIDSKGHIKLTDFGLASGTVSMERIESM 329
A FY +E+ C + LH+ +RDLKPEN L+D GHI+++D GLA
Sbjct: 286 ERALFYAAEILCGLEDLHRENTVYRDLKPENILLDDYGHIRISDLGLA------------ 333
Query: 330 KIRLQEVKNLEFPEFRERSMDDRRRMYNKLREEEVRYAHSTVGSPDYMALEVLEAKNYDF 389
VK E R R VG+ YMA EVL + Y
Sbjct: 334 ------VKIPEGDLIRGR-----------------------VGTVGYMAPEVLNNQRYGL 364
Query: 390 TVDYWSLGCILFESLVGYTPFSGNSTNETYENLRNWKHVLQRPKCDNGRYAFSDRTWELI 449
+ DYW LGC+++E + G +PF G E + + VL+ + + + FS+ +
Sbjct: 365 SPDYWGLGCLIYEMIEGQSPFRGRKEKVKREEVD--RRVLETEEVYS--HKFSEEAKSIC 420
Query: 450 TRLIA-DPINRLKSFE----HVKRMRYFSEIDFNTLRT--IHPPFIP 489
L+ D RL E VKR +F ++F L + PPF+P
Sbjct: 421 KMLLTKDAKQRLGCQEEGAAEVKRHPFFRNMNFKRLEAGMLDPPFVP 467
>At3g44610 [R] KOG0610 Putative serine/threonine protein kinase
Length = 472
Score = 112 bits (279), Expect = 2e-24
Identities = 101/355 (28%), Positives = 145/355 (40%), Gaps = 69/355 (19%)
Query: 219 TERDILTTTRSEWLVKLLYAFQDPQSLYLAMEFVPGGDFRTLLLNT--KFLQAPHARFYI 276
TER+IL + +L L A P+ L L EF PGGD L K RFY+
Sbjct: 126 TEREILESLDHPFLPTLYAAIDSPKWLCLLTEFCPGGDLHVLRQKQTHKRFHESAVRFYV 185
Query: 277 SEMFCAVNALHQLGYTHRDLKPENFLIDSKGHIKLTDFGLASGTVSMERIESMKIRLQEV 336
SE+ A+ LH LG +RDLKPEN L+ S GHI LTDF L+ + + +
Sbjct: 186 SEVIVAIEYLHMLGIVYRDLKPENVLVRSDGHIMLTDFDLSLKCDESTSTPQIVLNRNNL 245
Query: 337 KNLEFPEFRERSMDDRRR-----------------MYNKLREEEVRYAH----------- 368
N + + MD R+ + ++R + + H
Sbjct: 246 PNGSSDQNENQGMDHRQTTSSSCMIPNCIVPAVSCFHPRIRRRKKKTDHRNNGPELVAEP 305
Query: 369 ------STVGSPDYMALEV---------------------LEAKNYDFTVDYWSLGCILF 401
S VG+ +Y+A E+ + + + VD+W+LG +F
Sbjct: 306 VDVRSMSFVGTHEYLAPEIVSVYIMYNFPMWYPNMKRKMWMAGEGHGSAVDWWTLGIFMF 365
Query: 402 ESLVGYTPFSGNSTNETYENLRNWKHVLQRPKCDNGRYAFSDRTWELITRLIA-DPINRL 460
E G TPF G T N+ L+ PK A D LI++L+A DP RL
Sbjct: 366 ELFYGTTPFKGMDHELTLANI--VARALEFPKEPTIPSAAKD----LISQLLAKDPSRRL 419
Query: 461 KS---FEHVKRMRYFSEIDFNTLRTIHPPFIPQLDNEEDVGYFDDFTNEEHMARY 512
S VKR +F +++ L PPF+P +E + DD E H+ Y
Sbjct: 420 GSSLGATAVKRHPFFQGVNWALLMCTRPPFLPPPFRKELLS--DDICPETHVDYY 472
>SPBC106.10 [T] KOG0616 cAMP-dependent protein kinase catalytic subunit (PKA)
Length = 512
Score = 111 bits (278), Expect = 3e-24
Identities = 88/363 (24%), Positives = 149/363 (40%), Gaps = 67/363 (18%)
Query: 160 LRKRRLKPKH---------KDFEMITXXXXXXXXXXXLARKKDTKEICAXXXXXXXXXXX 210
L++RR++P +DF + L + + A
Sbjct: 180 LQRRRIRPADHTTKDRYGIQDFNFLQTLGTGSFGRVHLVQSNHNRLYYAIKVLEKKKIVD 239
Query: 211 XEGTDHVLTERDILTTTRSEWLVKLLYAFQDPQSLYLAMEFVPGGDFRTLLLNTKFLQAP 270
+ +H ER IL+ + ++ L FQD ++L++ M+F GG+ +LL
Sbjct: 240 MKQIEHTCDERYILSRVQHPFITILWGTFQDAKNLFMVMDFAEGGELFSLLRKCHRFPEK 299
Query: 271 HARFYISEMFCAVNALHQLGYTHRDLKPENFLIDSKGHIKLTDFGLASGTVSMERIESMK 330
A+FY +E+ A++ LH +RDLKPEN L+D GH+K+ DFG A +R+ +
Sbjct: 300 VAKFYAAEVILALDYLHHNQIVYRDLKPENLLLDRFGHLKIVDFGFA------KRVSTSN 353
Query: 331 IRLQEVKNLEFPEFRERSMDDRRRMYNKLREEEVRYAHSTVGSPDYMALEVLEAKNYDFT 390
+ G+PDY+A E++ K Y+
Sbjct: 354 ------------------------------------CCTLCGTPDYLAPEIISLKPYNKA 377
Query: 391 VDYWSLGCILFESLVGYTPFSGNSTNETYENLRNWKHVLQRPKCDNGRYAFSDRTWELIT 450
D+WSLG ++FE L GY PF + + YEN+ K N FS + +L++
Sbjct: 378 ADWWSLGILIFEMLAGYPPFYSENPMKLYENILEGK--------VNYPSYFSPASIDLLS 429
Query: 451 RLIADPI-----NRLKSFEHVKRMRYFSEIDFNTL--RTIHPPFIPQLD-NEEDVGYFDD 502
L+ I N + +F +I ++ + R I P++P + D FD
Sbjct: 430 HLLQRDITCRYGNLKDGSMDIIMHPWFRDISWDKILTRKIEVPYVPPIQAGMGDSSQFDA 489
Query: 503 FTN 505
+ +
Sbjct: 490 YAD 492
>At5g40030 [R] KOG0610 Putative serine/threonine protein kinase
Length = 499
Score = 111 bits (278), Expect = 3e-24
Identities = 91/308 (29%), Positives = 141/308 (45%), Gaps = 43/308 (13%)
Query: 219 TERDILTTTRSEWLVKLLYAFQDPQSLYLAMEFVPGGDFRTLLLNT--KFLQAPHARFYI 276
TER+IL +L L F+ + L MEF GGD L K ARFY
Sbjct: 161 TEREILGLLDHPFLPTLYSHFETEKFSCLLMEFCSGGDLHILRQKQPGKHFSELAARFYA 220
Query: 277 SEMFCAVNALHQLGYTHRDLKPENFLIDSKGHIKLTDFGLA-SGTVSMERIESMKIRLQE 335
SE+ A+ LH +G +RDLKPEN ++ GHI L+DF L+ VS I+S
Sbjct: 221 SEVLLALEYLHMMGVVYRDLKPENVMVREDGHIMLSDFDLSLQSFVSPTLIQSTSQPSCH 280
Query: 336 VKN------------------LEFPEFRERSMDDRRRMYNK-----------LREEEVRY 366
+ + ++ F+ R ++++ R + E
Sbjct: 281 IASYCIQPPCIDPSCKLPVACIQPSCFKPRFLNNKPRKAKTEKAGSDSLPMLIAEPTAAR 340
Query: 367 AHSTVGSPDYMALEVLEAKNYDFTVDYWSLGCILFESLVGYTPFSGNSTNETYENLRNWK 426
+ S VG+ +Y+A E++ + +VD+W+ G L+E L G TPF GN ET N+
Sbjct: 341 SMSFVGTHEYLAPEIIRGDGHGSSVDWWTFGIFLYELLTGKTPFKGNGNRETLFNV---- 396
Query: 427 HVLQRPKCDNGRYAFSDRTWELITRLIA-DPINRL---KSFEHVKRMRYFSEIDFNTLRT 482
V Q K G +F+ + +LI L+ DP RL K +K+ +F+ +++ +R+
Sbjct: 397 -VGQPLKFPEGSISFAAK--DLIRGLLTKDPKKRLGFKKGATEIKQHPFFNNVNWALIRS 453
Query: 483 IHPPFIPQ 490
PP IP+
Sbjct: 454 TTPPEIPK 461
>At4g26610 [R] KOG0610 Putative serine/threonine protein kinase
Length = 506
Score = 111 bits (278), Expect = 3e-24
Identities = 88/310 (28%), Positives = 140/310 (44%), Gaps = 43/310 (13%)
Query: 219 TERDILTTTRSEWLVKLLYAFQDPQSLYLAMEFVPGGDFRTLLLNT--KFLQAPHARFYI 276
TER+IL +L L F+ + L MEF PGGD TL K A+FY+
Sbjct: 170 TEREILQCLDHPFLPTLYSHFETEKFSCLVMEFCPGGDLHTLRQRQPGKRFSEQAAKFYV 229
Query: 277 SEMFCAVNALHQLGYTHRDLKPENFLIDSKGHIKLTDFGLA-SGTVSMERIESMKIRLQE 335
+E+ A+ LH LG +RDLKPEN L+ GH+ L+DF L+ TVS + S + +
Sbjct: 230 AEVLLAMEYLHMLGIIYRDLKPENVLVRDDGHVMLSDFDLSLRCTVSPTVVRSTVLASEG 289
Query: 336 VKNLEF---------------------PEFRERSMDDRRRMYNK-----------LREEE 363
KN + P + ++M N+ + E
Sbjct: 290 QKNSGYCAQPACIQQPSCISAPTTCFSPRYFSSKSKKDKKMKNETGNQVSPLPELVAEPT 349
Query: 364 VRYAHSTVGSPDYMALEVLEAKNYDFTVDYWSLGCILFESLVGYTPFSGNSTNETYENLR 423
+ S VG+ +Y+A E+++ + + VD+W+ G L+E L G TPF G+ T N+
Sbjct: 350 SARSMSFVGTHEYLAPEIIKGEGHGSAVDWWTFGIFLYELLFGKTPFKGSGNRATLFNVV 409
Query: 424 NWKHVLQRPKCDNGRYAFSDRTWELITRLIADPINRL---KSFEHVKRMRYFSEIDFNTL 480
L+ P+ +A D L L+ +P +RL + +K+ +F +++ +
Sbjct: 410 G--QPLRFPESPVVSFAARDLIRSL---LVKEPQHRLAYKRGATEMKQHPFFEGVNWALV 464
Query: 481 RTIHPPFIPQ 490
R PP IP+
Sbjct: 465 RCASPPEIPK 474
>YMR001c [D] KOG0575 Polo-like serine/threonine protein kinase
Length = 705
Score = 109 bits (273), Expect = 1e-23
Identities = 86/348 (24%), Positives = 139/348 (39%), Gaps = 61/348 (17%)
Query: 191 KKDTKEICAXXXXXXXXXXXXEGTDHVLTERDILTTTRSEWLVKLLYAFQDPQSLYLAME 250
K D+ EI A + +L+E I + +V+ + F+D ++Y+ +E
Sbjct: 100 KDDSGEIFAAKTVAKASIKSEKTRKKLLSEIQIHKSMSHPNIVQFIDCFEDDSNVYILLE 159
Query: 251 FVPGGDFRTLLLNTKFLQAPHARFYISEMFCAVNALHQLGYTHRDLKPENFLIDSKGHIK 310
P G LL K L P RF+ +++ A+ +H HRDLK N DS ++K
Sbjct: 160 ICPNGSLMELLKRRKVLTEPEVRFFTTQICGAIKYMHSRRVIHRDLKLGNIFFDSNYNLK 219
Query: 311 LTDFGLASGTVSMERIESMKIRLQEVKNLEFPEFRERSMDDRRRMYNKLREEEVRYAHST 370
+ DFGLA+ + E E +Y +
Sbjct: 220 IGDFGLAAVLAN--------------------------------------ESERKY--TI 239
Query: 371 VGSPDYMALEVLEAKN--YDFTVDYWSLGCILFESLVGYTPFSGNSTNETYENL--RNWK 426
G+P+Y+A EVL K+ + F VD WSLG +L+ L+G PF N YE + R++
Sbjct: 240 CGTPNYIAPEVLMGKHSGHSFEVDIWSLGVMLYALLIGKPPFQARDVNTIYERIKCRDFS 299
Query: 427 HVLQRPKCDNGRYAFSDRTWELITRLIADPINRLKSFEHVKRMRYFSEIDFNTLRTIHPP 486
+P D G+ D + S + ++R +D+ R PP
Sbjct: 300 FPRDKPISDEGKILIRD----------------ILSLDPIERPSLTEIMDYVWFRGTFPP 343
Query: 487 FIPQLDNEEDVGYFDDFTNEEHMARYVDVFKRQDRLTAMVDDSLSDSK 534
IP E F+D E+ + + D ++ L +M D + K
Sbjct: 344 SIPSTVMSE-APNFEDIPEEQSLVNFKDCMEKSLLLESMSSDKIQRQK 390
>YDR466w [T] KOG0592 3-phosphoinositide-dependent protein kinase (PDK1)
Length = 898
Score = 109 bits (273), Expect = 1e-23
Identities = 68/258 (26%), Positives = 120/258 (46%), Gaps = 24/258 (9%)
Query: 222 DILTTTRSEWLVKLLYAFQDPQSLYLAMEFVPGGDFRTLLLNTKFLQAPHARFYISEMFC 281
++L ++KL Y F D ++LY ++F PGG+ +LL R + +++
Sbjct: 65 NLLAQKHHAGIIKLYYTFHDEENLYFVLDFAPGGELLSLLHKMGTFNDIWTRHFTAQLID 124
Query: 282 AVNALHQLGYTHRDLKPENFLIDSKGHIKLTDFGLASGTVSMERIESMKIRLQEVKNLEF 341
A+ +H G HRDLKPEN L+D G + +TDFG A+ +S K F
Sbjct: 125 ALEFIHSHGIIHRDLKPENVLLDRDGRLMITDFGAAATIDPSLSGDSAK----------F 174
Query: 342 PEFRERSMDDRRRMYNKLREEEVRYAHSTVGSPDYMALEVLEAKNYDFTVDYWSLGCILF 401
S D++ S VG+ +Y++ E+L + D W+LGC+++
Sbjct: 175 NSDSNGSKDNQN-------------CASFVGTAEYVSPELLLYNQCGYGSDIWALGCMIY 221
Query: 402 ESLVGYTPFSGNSTNETYENLRNWKHVL-QRPKCDNGRYAFSDRTWELITRLIADPINRL 460
+ + G PF G + +T+E + + + +N + L+ +++ +N
Sbjct: 222 QFVQGQPPFRGENELKTFEKIVALDYPWGPNNRINNSTSPINPLVINLVQKILVIEVNER 281
Query: 461 KSFEHVKRMRYFSEIDFN 478
S E +KR YFS++D+N
Sbjct: 282 ISLEQIKRHPYFSKVDWN 299
>Hs4506067 [T] KOG0696 Serine/threonine protein kinase
Length = 672
Score = 109 bits (272), Expect = 1e-23
Identities = 86/332 (25%), Positives = 140/332 (41%), Gaps = 56/332 (16%)
Query: 168 KHKDFEMITXXXXXXXXXXXLARKKDTKEICAXXXXXXXXXXXXEGTDHVLTERDILTTT 227
K DF + LA +K T+E+ A + + + E+ +L
Sbjct: 335 KLTDFNFLMVLGKGSFGKVMLADRKGTEELYAIKILKKDVVIQDDDVECTMVEKRVLALL 394
Query: 228 -RSEWLVKLLYAFQDPQSLYLAMEFVPGGDFRTLLLNTKFLQAPHARFYISEMFCAVNAL 286
+ +L +L FQ LY ME+V GGD + + P A FY +E+ + L
Sbjct: 395 DKPPFLTQLHSCFQTVDRLYFVMEYVNGGDLMYHIQQVGKFKEPQAVFYAAEISIGLFFL 454
Query: 287 HQLGYTHRDLKPENFLIDSKGHIKLTDFGLASGTVSMERIESMKIRLQEVKNLEFPEFRE 346
H+ G +RDLK +N ++DS+GHIK+ DFG+ +E
Sbjct: 455 HKRGIIYRDLKLDNVMLDSEGHIKIADFGMC---------------------------KE 487
Query: 347 RSMDDRRRMYNKLREEEVRYAHSTVGSPDYMALEVLEAKNYDFTVDYWSLGCILFESLVG 406
MD + G+PDY+A E++ + Y +VD+W+ G +L+E L G
Sbjct: 488 HMMDGVT-------------TRTFCGTPDYIAPEIIAYQPYGKSVDWWAYGVLLYEMLAG 534
Query: 407 YTPFSGNSTNETYENLRNWKHVLQRPKCDNGRYAFSDRTWELITRLIA-DPINRL----K 461
PF G +E ++++ +H + PK + S + L+ P RL +
Sbjct: 535 QPPFDGEDEDELFQSI--MEHNVSYPK------SLSKEAVSICKGLMTKHPAKRLGCGPE 586
Query: 462 SFEHVKRMRYFSEIDFNTL--RTIHPPFIPQL 491
V+ +F ID+ L R I PPF P++
Sbjct: 587 GERDVREHAFFRRIDWEKLENREIQPPFKPKV 618
>Hs13384594 [T] KOG0696 Serine/threonine protein kinase
Length = 697
Score = 109 bits (272), Expect = 1e-23
Identities = 71/256 (27%), Positives = 107/256 (41%), Gaps = 46/256 (17%)
Query: 171 DFEMITXXXXXXXXXXXLARKKDTKEICAXXXXXXXXXXXXEGTDHVLTERDILTTT--- 227
DF + LA ++ + E+ A + D L E+ +L
Sbjct: 350 DFSFLMVLGKGSFGKVMLAERRGSDELYAIKILKKDVIVQDDDVDCTLVEKRVLALGGRG 409
Query: 228 ---RSEWLVKLLYAFQDPQSLYLAMEFVPGGDFRTLLLNTKFLQAPHARFYISEMFCAVN 284
R +L +L FQ P LY ME+V GGD + + PHA FY +E+ +
Sbjct: 410 PGGRPHFLTQLHSTFQTPDRLYFVMEYVTGGDLMYHIQQLGKFKEPHAAFYAAEIAIGLF 469
Query: 285 ALHQLGYTHRDLKPENFLIDSKGHIKLTDFGLASGTVSMERIESMKIRLQEVKNLEFPEF 344
LH G +RDLK +N ++D++GHIK+TDFG+ V FP
Sbjct: 470 FLHNQGIIYRDLKLDNVMLDAEGHIKITDFGMCKENV-------------------FPGT 510
Query: 345 RERSMDDRRRMYNKLREEEVRYAHSTVGSPDYMALEVLEAKNYDFTVDYWSLGCILFESL 404
R+ G+PDY+A E++ + Y +VD+WS G +L+E L
Sbjct: 511 TTRTF---------------------CGTPDYIAPEIIAYQPYGKSVDWWSFGVLLYEML 549
Query: 405 VGYTPFSGNSTNETYE 420
G PF G E ++
Sbjct: 550 AGQPPFDGEDEEELFQ 565
>Hs4504101 [T] KOG0986 G protein-coupled receptor kinase
Length = 576
Score = 108 bits (271), Expect = 2e-23
Identities = 84/287 (29%), Positives = 133/287 (46%), Gaps = 54/287 (18%)
Query: 212 EGTDHVLTERDILTTTRSEWLVKLLYAFQDPQSLYLAMEFVPGGDFRTLLLNTKFLQAPH 271
+G L E+ IL S ++V L YA++ +L L + + GGD + + + P
Sbjct: 226 KGEAMALNEKQILEKVNSRFVVSLAYAYETKDALCLVLTLMNGGDLKFHIYHMGQAGFPE 285
Query: 272 AR--FYISEMFCAVNALHQLGYTHRDLKPENFLIDSKGHIKLTDFGLASGTVSMERIESM 329
AR FY +E+ C + LH+ +RDLKPEN L+D GHI+++D GLA V + +++
Sbjct: 286 ARAVFYAAEICCGLEDLHRERIVYRDLKPENILLDDHGHIRISDLGLA---VHVPEGQTI 342
Query: 330 KIRLQEVKNLEFPEFRERSMDDRRRMYNKLREEEVRYAHSTVGSPDYMALEVLEAKNYDF 389
K R VG+ YMA EV++ + Y F
Sbjct: 343 KGR--------------------------------------VGTVGYMAPEVVKNERYTF 364
Query: 390 TVDYWSLGCILFESLVGYTPFSGNSTNETYENLRNWKHVLQRPKCDNGRYAFSDRTWELI 449
+ D+W+LGC+L+E + G +PF E + + V + P+ + R FS + L
Sbjct: 365 SPDWWALGCLLYEMIAGQSPFQQRKKKIKREEVE--RLVKEVPEEYSER--FSPQARSLC 420
Query: 450 TRLIA-DPINRL----KSFEHVKRMRYFSEIDFNTLRT--IHPPFIP 489
++L+ DP RL S VK F +++F L + PPF P
Sbjct: 421 SQLLCKDPAERLGCRGGSAREVKEHPLFKKLNFKRLGAGMLEPPFKP 467
>At5g55910 [R] KOG0610 Putative serine/threonine protein kinase
Length = 498
Score = 108 bits (271), Expect = 2e-23
Identities = 88/314 (28%), Positives = 141/314 (44%), Gaps = 47/314 (14%)
Query: 219 TERDILTTTRSEWLVKLLYAFQDPQSLYLAMEFVPGGDFRTLLLNT--KFLQAPHARFYI 276
TER+IL +L L F+ + L MEF PGGD TL K A+FY+
Sbjct: 156 TEREILQCLDHPFLPTLYSHFETEKFSCLVMEFCPGGDLHTLRQRQPGKRFTEQAAKFYV 215
Query: 277 SEMFCAVNALHQLGYTHRDLKPENFLIDSKGHIKLTDFGLA-SGTVSMERIESMKIR--- 332
+E+ A+ LH LG +RDLKPEN L+ GH+ L+DF L+ TVS+ + S +
Sbjct: 216 AEVLLAMEYLHMLGIIYRDLKPENVLVRDDGHVMLSDFDLSLRCTVSLSIVRSANVGSEG 275
Query: 333 --------LQEVKNLEFPE---------FRERSMDDRRRMYNKLREEEVRY--------- 366
Q+ ++ P F R + + K + E +
Sbjct: 276 LSKNSVSCSQQPACIQQPSCISMAPTSCFGPRFFSSKSKKDKKPKTENGNHQVTPLPELV 335
Query: 367 -------AHSTVGSPDYMALEVLEAKNYDFTVDYWSLGCILFESLVGYTPFSGNSTNETY 419
+ S VG+ +Y+A E+++ + + VD+W+ G L+E L G TPF G+ T
Sbjct: 336 AEPTGARSMSFVGTHEYLAPEIIKGEGHGSAVDWWTFGIFLYELLFGKTPFKGSGNRATL 395
Query: 420 ENLRNWKHVLQRPKCDNGRYAFSDRTWELITRLIADPINRL---KSFEHVKRMRYFSEID 476
N+ L+ P+ +A D L L+ +P +RL + +K+ +F ++
Sbjct: 396 FNVVG--QPLRFPESPVVSFAARDLIRSL---LVKEPQHRLAYKRGATEIKQHPFFEGVN 450
Query: 477 FNTLRTIHPPFIPQ 490
+ +R PP IP+
Sbjct: 451 WALVRCASPPEIPK 464
>Hs7019489 [T] KOG0694 Serine/threonine protein kinase
Length = 889
Score = 108 bits (270), Expect = 2e-23
Identities = 94/352 (26%), Positives = 150/352 (41%), Gaps = 60/352 (17%)
Query: 164 RLKPKHKDFEMITXXXXXXXXXXXLARKKDTKEICAXXXXXXXXXXXXEGTDHVLTERDI 223
R P+ +DF + L + K T + A + + + E+ I
Sbjct: 551 RKPPRLQDFRCLAVLGRGHFGKVLLVQFKGTGKYYAIKALKKQEVLSRDEIESLYCEKRI 610
Query: 224 LTT---TRSEWLVKLLYAFQDPQSLYLAMEFVPGGDFRTLLLNTKFLQAPHARFYISEMF 280
L T +L+ LL FQ EFVPGGD + F + P ARFY++ +
Sbjct: 611 LEAVGCTGHPFLLSLLVCFQTSSHARFVTEFVPGGDLMMQIHEDVFPE-PQARFYVACVV 669
Query: 281 CAVNALHQLGYTHRDLKPENFLIDSKGHIKLTDFGLASGTVSMERIESMKIRLQEVKNLE 340
+ LH+ +RDLK +N L+D++G +K+ DFGL +
Sbjct: 670 LGLQFLHEKKIIYRDLKLDNLLLDAQGFLKIADFGLCKEGIG------------------ 711
Query: 341 FPEFRERSMDDRRRMYNKLREEEVRYAHSTVGSPDYMALEVLEAKNYDFTVDYWSLGCIL 400
F +R+ + G+P+++A EVL + Y VD+W+LG +L
Sbjct: 712 ---FGDRT-------------------STFCGTPEFLAPEVLTQEAYTQAVDWWALGVLL 749
Query: 401 FESLVGYTPFSGNSTNETYENLRNWKHVLQRPKCDNGRYAFSDRTWELITRLIAD-PINR 459
+E LVG PF G++ E ++ + N + P S + E I +L+ P R
Sbjct: 750 YEMLVGECPFPGDTEEEVFDCIVN----MDAPYPG----FLSVQGLEFIQKLLQKCPEKR 801
Query: 460 L----KSFEHVKRMRYFSEIDFNTL--RTIHPPFIPQLDNEEDVGYFD-DFT 504
L + E +K +F ++ L RTI PPF+P L D+ YF+ +FT
Sbjct: 802 LGAGEQDAEEIKVQPFFRTTNWQALLARTIQPPFVPTLCGPADLRYFEGEFT 853
>At5g47750 [R] KOG0610 Putative serine/threonine protein kinase
Length = 586
Score = 108 bits (270), Expect = 2e-23
Identities = 88/310 (28%), Positives = 137/310 (43%), Gaps = 40/310 (12%)
Query: 219 TERDILTTTRSEWLVKLLYAFQDPQSLYLAMEFVPGGDFRTLLLNT--KFLQAPHARFYI 276
TER+IL + +L L F+ + L MEF PGGD TL K +FYI
Sbjct: 238 TEREILQSLDHPFLPTLYTHFETEKFSCLVMEFCPGGDLHTLRQRQPGKHFSEQAVKFYI 297
Query: 277 SEMFCAVNALHQLGYTHRDLKPENFLIDSKGHIKLTDFGLA-SGTVSMERIESMKIRLQE 335
+E A+ LH LG +RDLKPEN L+ GHI L+DF L+ VS ++S I
Sbjct: 298 AESLLALEYLHMLGIVYRDLKPENVLVREDGHIMLSDFDLSLRCLVSPTLVKSAAIESDP 357
Query: 336 V-KNLEFPE------------------------FRERSMDDR----------RRMYNKLR 360
+ KN+ + F +S DR R + +
Sbjct: 358 LRKNVYCVQPACIEPSCIQPSCTVPTTCFSPRLFSSKSKKDRKPKNDTANQVRPLPELVA 417
Query: 361 EEEVRYAHSTVGSPDYMALEVLEAKNYDFTVDYWSLGCILFESLVGYTPFSGNSTNETYE 420
E + S VG+ +Y+A E+++ + + VD+W+ G L+E L G TPF G+ +T
Sbjct: 418 EPTDARSMSFVGTHEYLAPEIIKGEGHGSAVDWWTFGIFLYELLFGRTPFKGSGNRQTLF 477
Query: 421 NLRNWKHVLQRPKCDNGRYAFSDRTWELITRLIADPINRLKSFEHVKRMRYFSEIDFNTL 480
N+ L+ P+ +A D L+ + + + VK+ +F +++ +
Sbjct: 478 NVVG--QPLRFPETPVVSFAARDLIRGLLMKEPQQRLGFKRGATEVKQHPFFEGVNWALI 535
Query: 481 RTIHPPFIPQ 490
R PP IP+
Sbjct: 536 RCATPPEIPK 545
>At4g13000 [R] KOG0610 Putative serine/threonine protein kinase
Length = 372
Score = 107 bits (268), Expect = 4e-23
Identities = 84/287 (29%), Positives = 135/287 (46%), Gaps = 34/287 (11%)
Query: 248 AMEFVPGGDFRTLLL--NTKFLQAPHARFYISEMFCAVNALHQLGYTHRDLKPENFLIDS 305
A+++ PG D +L + + RFY +E+ A+ LH G +RDLKP+N +I
Sbjct: 97 AIDYCPGRDLNSLRKKQSEEMFSDEIIRFYAAELVIALEYLHNQGIVYRDLKPDNVMIQE 156
Query: 306 KGHIKLTDFGLASGTVSMERIESMKIRLQEVKNLEFPEFRERSMDDRRRMYNK------- 358
GH+ L DF L++ S L +ERS+ + N
Sbjct: 157 NGHLMLVDFDLSTNLPPRTPQSSFS----SSPRLSTATKKERSIFAFSGLCNSGISPDDS 212
Query: 359 -LREEEVRYA----HSTVGSPDYMALEVLEAKNYDFTVDYWSLGCILFESLVGYTPFSGN 413
R E ++ +S VG+ +Y+A EV+ +DF VD+WSLG +L+E L G TPF G+
Sbjct: 213 VSRSSESEFSGEKSNSFVGTEEYVAPEVITGSGHDFAVDWWSLGVVLYEMLYGATPFRGS 272
Query: 414 STNETYENLRNWKHVLQRPKCDNGRYAFSDRTWELITRLIADPINRLKSFEHVKRMRYFS 473
+ ET+ K + + P + D +L+ + DP R+ + E +K +F
Sbjct: 273 NRKETF-----LKILTEPPSLVGETTSLRDLVRKLLEK---DPSRRI-NVEGIKGHDFFK 323
Query: 474 EIDFN-TLRTIHPPFIPQLDNEE----DVGYF--DDFTNEEHMARYV 513
+D++ L+ PP+IP +N E DV F + FT EH ++
Sbjct: 324 GLDWDLVLKVSRPPYIPAPENYEISKIDVEKFVHEIFTKCEHNGNFI 370
>7302050 [T] KOG0986 G protein-coupled receptor kinase
Length = 714
Score = 107 bits (267), Expect = 5e-23
Identities = 85/294 (28%), Positives = 128/294 (42%), Gaps = 63/294 (21%)
Query: 212 EGTDHVLTERDILTTTRSEWLVKLLYAFQDPQSLYLAMEFVPGGDFRTLLLNT---KFLQ 268
+G VL E+ IL S ++V L YA++ +L L + + GGD + + N +
Sbjct: 349 KGESMVLIEKQILQKINSPFVVNLAYAYETKDALCLVLTIMNGGDLKFHIYNMGGEPGFE 408
Query: 269 APHARFYISEMFCAVNALHQLGYTHRDLKPENFLIDSKGHIKLTDFGLASGTVSMERIES 328
ARFY +E+ C + LH+ G +RD KPEN L+D GH++++D GLA
Sbjct: 409 LERARFYAAEVACGLQHLHKQGIVYRDCKPENILLDDHGHVRISDLGLA----------- 457
Query: 329 MKIRLQEVKNLEFPEFRERSMDDRRRMYNKLREEEVRYAHSTVGSPDYMALEVLEAKNYD 388
+E PE E VR TVG YMA EV++ + Y
Sbjct: 458 ----------VEIPE-----------------GEMVRGRVGTVG---YMAPEVIDNEKYA 487
Query: 389 FTVDYWSLGCILFESLVGYTPFSGNSTNETYENLRNWKHVLQRPKCDNGRYA--FSDRTW 446
F+ D++S GC+L+E + G PF E V +R K D +Y+ F+D
Sbjct: 488 FSPDWFSFGCLLYEMIEGQAPFRMRKEKVKRE------EVDRRVKEDPEKYSSKFNDEAK 541
Query: 447 ELITRLIADPI-------NRLKSFEHVKRMRYFSEIDFNTLR----TIHPPFIP 489
+ +L+A I N + V +F N R + PPF+P
Sbjct: 542 SMCQQLLAKSIKQRLGCRNGRMGGQDVMAHPFFHSTQLNWRRLEAGMLEPPFVP 595
>SPBC12D12.04c [T] KOG0694 Serine/threonine protein kinase
Length = 1016
Score = 106 bits (265), Expect = 8e-23
Identities = 86/352 (24%), Positives = 150/352 (42%), Gaps = 68/352 (19%)
Query: 170 KDFEMITXXXXXXXXXXXLARKKDTKEICAXXXXXXXXXXXXEGTDHVLTERDILTTTRS 229
+DF ++ LA K K++ A + + +E+ +
Sbjct: 681 EDFTFLSVLGKGNFGKVMLAELKSEKQLYAIKVLKKEFILENDEVESTKSEKRVFLVANR 740
Query: 230 E---WLVKLLYAFQDPQSLYLAMEFVPGGDFRTLLLNTKFLQAPHARFYISEMFCAVNAL 286
E +LV L FQ +Y M+FV GGD + +F + A+FY +E+ A+
Sbjct: 741 ERHPFLVNLHSCFQTETRIYFVMDFVSGGDLMLHIQQEQFSRR-RAQFYAAEVCLALKYF 799
Query: 287 HQLGYTHRDLKPENFLIDSKGHIKLTDFGLASGTVSMERIESMKIRLQEVKNLEFPEFRE 346
H G +RDLK +N L+ GH+K+ D+GL
Sbjct: 800 HDNGIIYRDLKLDNILLSPDGHVKVADYGLC----------------------------- 830
Query: 347 RSMDDRRRMYNKLREEEVRYAHSTV---GSPDYMALEVLEAKNYDFTVDYWSLGCILFES 403
+E++ + ++T G+P++MA E+L + Y +VD+W+ G ++++
Sbjct: 831 --------------KEDMWHDNTTATFCGTPEFMAPEILLEQQYTRSVDWWAFGVLIYQM 876
Query: 404 LVGYTPFSGNSTNETYENLRNWK--HVLQRPKCDNGRYAFSDRTWELITRLIADPINRLK 461
L+G +PF G E ++ + + + + + P+ D L L DP RL
Sbjct: 877 LLGQSPFRGEDEEEIFDAILSDEPLYPIHMPR---------DSVSILQQLLTRDPKKRLG 927
Query: 462 S----FEHVKRMRYFSEIDFNTL--RTIHPPFIPQLDNEEDVGYFD-DFTNE 506
S E V +FS I+++ + + PP+IP L++ D YFD +FT E
Sbjct: 928 SGPNDAEDVMTHPFFSNINWDDIYHKRTQPPYIPSLNSPTDTKYFDEEFTRE 979
>At3g25250 [R] KOG0610 Putative serine/threonine protein kinase
Length = 421
Score = 106 bits (265), Expect = 8e-23
Identities = 75/266 (28%), Positives = 127/266 (47%), Gaps = 24/266 (9%)
Query: 248 AMEFVPGGDFRTL--LLNTKFLQAPHARFYISEMFCAVNALHQLGYTHRDLKPENFLIDS 305
A+++ PG + +L + + RFY +E+ A++ LH G +RDLKP+N +I
Sbjct: 100 AIDYCPGQNLNSLRKMQSESMFSDEIIRFYAAELVLALDYLHNQGIVYRDLKPDNVMIQE 159
Query: 306 KGHIKLTDFGLASGTVSMERIESMKIR-----LQEVKNL-EFPEF------RERSMDDRR 353
GH+ L DF L++ S + ++ K L F F + S+
Sbjct: 160 NGHLMLIDFDLSTNLAPRTPQPSPSLSKPSPTMKRKKRLFRFTSFCNSGISPQESISVHS 219
Query: 354 RMYNKLREEEVRYAHSTVGSPDYMALEVLEAKNYDFTVDYWSLGCILFESLVGYTPFSGN 413
+ + ++S VG+ +Y+A EV+ +DF VD+WSLG +L+E L G TPF G+
Sbjct: 220 SSTLAVSDSSGEKSNSFVGTEEYVAPEVISGDGHDFAVDWWSLGVVLYEMLYGATPFRGS 279
Query: 414 STNETYENLRNWKHVLQRPKCDNGRYAFSDRTWELITRLIADPINRLKSFEHVKRMRYFS 473
+ ET+ +L +P G + +LI RL+ +R + E +K +F
Sbjct: 280 NRKETF------YRILSKPPNLTGE---TTSLRDLIRRLLEKDPSRRINVEEIKGHDFFR 330
Query: 474 EIDFNTLRTI-HPPFIPQLDNEEDVG 498
+D+ + + PP+IP D+ D G
Sbjct: 331 GVDWEKVILVSRPPYIPAPDDGGDKG 356
>At3g14370 [R] KOG0610 Putative serine/threonine protein kinase
Length = 480
Score = 106 bits (265), Expect = 8e-23
Identities = 80/287 (27%), Positives = 130/287 (44%), Gaps = 26/287 (9%)
Query: 217 VLTERDILTTTRSEWLVKLLYAFQDPQSLYLAMEFVPGGDFRTLLLNTKFLQAP--HARF 274
V TE +IL+ +L L + L +++ P GD +LL + P RF
Sbjct: 133 VETEAEILSLLDHPFLPTLYARIDESHYTCLLIDYAPNGDLHSLLRKQPGNRLPIQPVRF 192
Query: 275 YISEMFCAVNALHQLGYTHRDLKPENFLIDSKGHIKLTDFGLASGTVSMERIESMKIRLQ 334
+ +E+ A+ LH +G +RDLKPEN L+ GH+ L+DF L + + +S + R
Sbjct: 193 FAAEVLVALEYLHAMGIVYRDLKPENVLLREDGHVMLSDFDLCFKSDVVPTFKSRRYR-- 250
Query: 335 EVKNLEFPEFRERSMD----------DRRRMYNKLREEEV-RYAHSTVGSPDYMALEVLE 383
++ P R R +R + ++ E V ++ S VG+ +Y+A E++
Sbjct: 251 --RSSSSPSLRRRRSGCFSVAAEKKYEREEIVSEFAAEPVTAFSRSCVGTHEYLAPELVS 308
Query: 384 AKNYDFTVDYWSLGCILFESLVGYTPFSGNSTNETYENLRNWKHVLQRPKCDNGRYAFSD 443
+ VD+W+ G L+E L G TPF G S +T N+ V D
Sbjct: 309 GNGHGSGVDWWAFGIFLYELLYGTTPFKGESKEQTLRNI-----VSTTKTASFHMDGDLD 363
Query: 444 RTWELITR-LIADPINRL---KSFEHVKRMRYFSEIDFNTLRTIHPP 486
+LI + L+ DP RL + + +KR +F I + +R PP
Sbjct: 364 EARDLIEKLLVKDPRKRLGCARGAQDIKRHPFFDGIKWPLIRHYKPP 410
>At1g53700 [R] KOG0610 Putative serine/threonine protein kinase
Length = 476
Score = 106 bits (265), Expect = 8e-23
Identities = 82/283 (28%), Positives = 128/283 (44%), Gaps = 14/283 (4%)
Query: 216 HVLTERDILTTTRSEWLVKLLYAFQDPQSLYLAMEFVPGGDFRTLLLNTKFLQAPHA--R 273
HV TE +IL+ +L L L +++ P GD +LL + P + R
Sbjct: 138 HVETEAEILSLLDHPFLPTLYARIDASHYTCLLIDYCPNGDLHSLLRKQPNNRLPISPVR 197
Query: 274 FYISEMFCAVNALHQLGYTHRDLKPENFLIDSKGHIKLTDFGLASGTVSMERIESMKIRL 333
F+ +E+ A+ LH LG +RDLKPEN LI GHI L+DF L + S + R
Sbjct: 198 FFAAEVLVALEYLHALGIVYRDLKPENILIREDGHIMLSDFDLCFKADVVPTFRSRRFRR 257
Query: 334 QEVKNLEFPE----FRERSMDDRRRMYNKLREEEV-RYAHSTVGSPDYMALEVLEAKNYD 388
+ F +R + + E V ++ S VG+ +Y+A E++ +
Sbjct: 258 TSSSPRKTRRGGGCFSTEVEYEREEIVAEFAAEPVTAFSKSCVGTHEYLAPELVAGNGHG 317
Query: 389 FTVDYWSLGCILFESLVGYTPFSGNSTNETYENLRNWKHVLQRPKCDNGRYAFSDRTWEL 448
VD+W+ G L+E L G TPF G + +T N+ + V + + G D +L
Sbjct: 318 SGVDWWAFGIFLYEMLYGTTPFKGGTKEQTLRNIVSNDDVAFTLE-EEGMVEAKDLIEKL 376
Query: 449 ITRLIADPINRL---KSFEHVKRMRYFSEIDFNTLRTIHPPFI 488
L+ DP RL + + +KR +F I + +R PP I
Sbjct: 377 ---LVKDPRKRLGCARGAQDIKRHEFFEGIKWPLIRNYKPPEI 416
>Hs8923754 [RT] KOG0598 Ribosomal protein S6 kinase and related proteins
Length = 414
Score = 105 bits (262), Expect = 2e-22
Identities = 84/348 (24%), Positives = 147/348 (42%), Gaps = 67/348 (19%)
Query: 188 LARKKDTKEICAXXXXXXXXXXXXEGTDHVLTERDILTTTRSEWLVKLLYAFQDPQSLYL 247
+ +K+DTK++ A + +V E I+ +LV L Y+FQD + +++
Sbjct: 39 IVQKRDTKKMYAMKYMNKQKCIERDEVRNVFRELQIMQGLEHPFLVNLWYSFQDEEDMFM 98
Query: 248 AMEFVPGGDFRTLLLNTKFLQAPHARFYISEMFCAVNALHQLGYTHRDLKPENFLIDSKG 307
++ + GGD R L + YI E+ A+ L + HRD+KP+N L+D G
Sbjct: 99 VVDLLLGGDLRYHLQQNVHFTEGTVKLYICELALALEYLQRYHIIHRDIKPDNILLDEHG 158
Query: 308 HIKLTDFGLASGTVSMERIESMKIRLQEVKNLEFPEFRERSMDDRRRMYNKLREEEVRYA 367
H+ +TDF +A+ ER SM
Sbjct: 159 HVHITDFNIATVVKGAERASSM-------------------------------------- 180
Query: 368 HSTVGSPDYMALEVLE-----AKNYDFTVDYWSLGCILFESLVGYTPFSGNSTNETYENL 422
G+ YMA EV + Y + VD+WSLG +E L G+ P+ +S E
Sbjct: 181 ---AGTKPYMAPEVFQVYMDRGPGYSYPVDWWSLGITAYELLRGWRPYEIHSVTPIDE-- 235
Query: 423 RNWKHVLQRPKCDNGRYAFSDRTW-----ELITRLIA-DPINRLKSFEHVKRMRYFSEID 476
+L K + Y+ TW L+ +L+ DP +R+ S ++ + Y ++++
Sbjct: 236 -----ILNMFKVERVHYS---STWCKGMVALLRKLLTKDPESRVSSLHDIQSVPYLADMN 287
Query: 477 FNTL--RTIHPPFIPQLDNEEDVGYFDDFTNEEHMARYVDVFKRQDRL 522
++ + + + P F+P N+ + F EE + + K++ RL
Sbjct: 288 WDAVFKKALMPGFVP---NKGRLNCDPTFELEEMILESKPLHKKKKRL 332
>Hs21166359 [T] KOG0986 G protein-coupled receptor kinase
Length = 553
Score = 105 bits (262), Expect = 2e-22
Identities = 89/306 (29%), Positives = 138/306 (45%), Gaps = 61/306 (19%)
Query: 213 GTDHVLTERDILTTTRSEWLVKLLYAFQDPQSLYLAMEFVPGGDFRTLLLN--TKFLQAP 270
G L E++IL S ++V L YAF+ L L M + GGD + + N T+ L
Sbjct: 232 GEKMALLEKEILEKVSSPFIVSLAYAFESKTHLCLVMSLMNGGDLKFHIYNVGTRGLDMS 291
Query: 271 HARFYISEMFCAVNALHQLGYTHRDLKPENFLIDSKGHIKLTDFGLASGTVSMERIESMK 330
FY +++ C + LH+LG +RD+KPEN L+D G+ +L+D GLA V M+ + +
Sbjct: 292 RVIFYSAQIACGMLHLHELGIVYRDMKPENVLLDDLGNCRLSDLGLA---VEMKGGKPIT 348
Query: 331 IRLQEVKNLEFPEFRERSMDDRRRMYNKLREEEVRYAHSTVGSPDYMALEVL-EAKNYDF 389
R G+ YMA E+L E +Y +
Sbjct: 349 QR--------------------------------------AGTNGYMAPEILMEKVSYSY 370
Query: 390 TVDYWSLGCILFESLVGYTPFSGNSTNETYENLRNWKHVLQRPKCDNGRYAFSDRTWEL- 448
VD++++GC ++E + G TPF + E+L+ QR D ++ + T E
Sbjct: 371 PVDWFAMGCSIYEMVAGRTPFKDYKEKVSKEDLK------QRTLQDEVKFQHDNFTEEAK 424
Query: 449 -ITRLI--ADPINRLKSFE---HVKRMRYFSEIDFNTLRT--IHPPFI--PQLDNEEDVG 498
I RL P RL S E ++ +F I+F L I PPF+ P + +D+
Sbjct: 425 DICRLFLAKKPEQRLGSREKSDDPRKHHFFKTINFPRLEAGLIEPPFVPDPSVVYAKDIA 484
Query: 499 YFDDFT 504
DDF+
Sbjct: 485 EIDDFS 490
>At2g34650 [R] KOG0610 Putative serine/threonine protein kinase
Length = 438
Score = 105 bits (261), Expect = 2e-22
Identities = 89/292 (30%), Positives = 134/292 (45%), Gaps = 30/292 (10%)
Query: 220 ERDILTTTRSEWLVKLLYAFQDPQSLYLAMEFVPGGDFRTLLLNT--KFLQAPHARFYIS 277
E+ IL +L L F+ + ME+ GGD +L + ARFY +
Sbjct: 128 EKTILKMLDHPFLPTLYAEFEASHFSCIVMEYCSGGDLHSLRHRQPHRRFSLSSARFYAA 187
Query: 278 EMFCAVNALHQLGYTHRDLKPENFLIDSKGHIKLTDFGLASGTVSMERIESMKIRLQEVK 337
E+ A+ LH LG +RDLKPEN L+ S GHI L+DF L+ + S+ +ES E +
Sbjct: 188 EVLVALEYLHMLGIIYRDLKPENILVRSDGHIMLSDFDLSLCSDSIAAVESSS-SSPENQ 246
Query: 338 NLEFPEFRERSMDDRRRMYNK-LREEEVRYAHST---------------VGSPDYMALEV 381
L P R R++ + LR ++V+ T VG+ +Y+A EV
Sbjct: 247 QLRSP----RRFTRLARLFQRVLRSKKVQTLEPTRLFVAEPVTARSGSFVGTHEYVAPEV 302
Query: 382 LEAKNYDFTVDYWSLGCILFESLVGYTPFSGNSTNETYENLRNWKHVLQRPKCDNGRYAF 441
++ VD+W+ G L+E + G TPF + + N+ K L P D+ F
Sbjct: 303 ASGGSHGNAVDWWAFGVFLYEMIYGKTPFVAPTNDVILRNI--VKRQLSFP-TDSPATMF 359
Query: 442 SDRTWELITRLI-ADPINRL---KSFEHVKRMRYFSEIDFNTLRTIHPPFIP 489
LI+ L+ DP RL + VK +F ++F +RT+ PP IP
Sbjct: 360 ELHARNLISGLLNKDPTKRLGSRRGAAEVKVHPFFKGLNFALIRTLTPPEIP 411
>At2g26700_2 [R] KOG0610 Putative serine/threonine protein kinase
Length = 437
Score = 104 bits (260), Expect = 3e-22
Identities = 81/317 (25%), Positives = 132/317 (41%), Gaps = 46/317 (14%)
Query: 220 ERDILTTTRSEWLVKLLYAFQDPQSLYLAMEFVPGGDFRTLLLN--TKFLQAPHARFYIS 277
E+ IL + L AF+ +L ME+ PGGD + L +K RFY +
Sbjct: 79 EKKILGMLDHPFCPTLYAAFEASHYSFLVMEYCPGGDLYAVRLRQPSKRFTISSTRFYAA 138
Query: 278 EMFCAVNALHQLGYTHRDLKPENFLIDSKGHIKLTDFGLA-------------------- 317
E A+ LH +G +RDLKPEN LI GH+ L+DF L+
Sbjct: 139 ETLVALEYLHMMGIVYRDLKPENVLIREDGHVMLSDFDLSFKCDVVPQFLSDNDRDRGHQ 198
Query: 318 --SGTVSMER-----------------IESMKIRLQEVKNLEFPEFRERSMDDRRRMYNK 358
+S+ R S + KN+ E + D +
Sbjct: 199 EDDDDISIRRKCSTPSCTTTPLNPVISCFSPTSSRRRKKNVVTTTIHENAADISGGCPSI 258
Query: 359 LREEEVRYAHSTVGSPDYMALEVLEAKNYDFTVDYWSLGCILFESLVGYTPFSGNSTNET 418
E + S VG+ +Y+A EV+ + + VD+W+ G L+E + G TPF G++ +T
Sbjct: 259 FAEPINARSKSFVGTHEYLAPEVISGQGHGSAVDWWTYGIFLYEMIFGRTPFKGDNNEKT 318
Query: 419 YENLRNW-----KHVLQRPKCDNGRYAFSDRTWELITRLIADPINRLKSFEHVKRMRYFS 473
N+ K ++ PK D +L+ + + LK +KR +F
Sbjct: 319 LVNILKAPLTFPKVIVNSPKEYEDMVNAQDLIIKLLVKNPKKRLGSLKGSIEIKRHEFFE 378
Query: 474 EIDFNTLRTIHPPFIPQ 490
+++ +R+I PP++P+
Sbjct: 379 GVNWALIRSIKPPWVPK 395
>CE03979 [T] KOG0614 cGMP-dependent protein kinase
Length = 581
Score = 104 bits (259), Expect = 4e-22
Identities = 81/300 (27%), Positives = 128/300 (42%), Gaps = 52/300 (17%)
Query: 216 HVLTERDILTTTRSEWLVKLLYAFQDPQSLYLAMEFVPGGDFRTLLLNTKFLQAPHARFY 275
HV++ER IL ++++V++ ++D + +Y+ ME GG+ T+L RFY
Sbjct: 317 HVVSERRILMQCDNDYIVRMYKTYRDSEKIYMLMEPCLGGEIWTILRKKGRFDNDLTRFY 376
Query: 276 ISEMFCAVNALHQLGYTHRDLKPENFLIDSKGHIKLTDFGLASGTVSMERIESMKIRLQE 335
+ A+ LH+ +RDLKPEN L+D G KL DFG A
Sbjct: 377 CAGAMEALEYLHRKNIVYRDLKPENMLLDRNGWPKLVDFGFA------------------ 418
Query: 336 VKNLEFPEFRERSMDDRRRMYNKLREEEVRYAHSTVGSPDYMALEVLEAKNYDFTVDYWS 395
+++ N R + G+ +Y+A E++ K +D +VD W+
Sbjct: 419 -----------------KKLKNGGR------TWTFCGTAEYVAPEIVLNKGHDLSVDIWA 455
Query: 396 LGCILFESLVGYTPFSGNSTNETYENLRNWKHVLQRPKCDNGRYAFSDRTWELITRLIAD 455
LG + E L G PFS TY + P R+ + +++ +
Sbjct: 456 LGIFMCELLTGSPPFSSTDPMVTYNAILKGLEKWAWP-----RFVTKEAIDMMLSLCKYE 510
Query: 456 PINRLKSFEHVKRMR---YFSEIDFNTLRT--IHPPFIPQLDNEEDVGYFDDFTNEEHMA 510
P RL F + +R +F DF R I PPFIP + N+ D FD F ++ A
Sbjct: 511 PTERL-GFGDIGEIRHHIWFDNFDFVGFRAHRIRPPFIPSVANDIDTSNFDTFPAFDNFA 569
>YFL033c [R] KOG0605 NDR and related serine/threonine kinases
Length = 1770
Score = 103 bits (257), Expect = 7e-22
Identities = 89/314 (28%), Positives = 133/314 (42%), Gaps = 34/314 (10%)
Query: 18 DDMVNFSFDTDAKVMLDPPSTPTRIRGSPSPTRSIVKNPENSLMDIDDDTQGDLTADITK 77
DD N D + PS T I S T + K N+ + L I+
Sbjct: 647 DDRTNEMLSRDKDSLQPQPSVDTTITSSTQATTTGTKTNSNNSTN---SVLPKLMTSISL 703
Query: 78 SPKKLPKDFYKKSS----KTKSKRLVSVCQMYFLDYYCDMFDYVISRRERTRQVINYLEE 133
+P++ F +S +T S +L+ D + S+ T E
Sbjct: 704 TPRRGSPSFGNLASHSMQQTNSFKLIH-------DKSPISSPFTFSKDFLT-------PE 749
Query: 134 QRRSNLMGTEQITNEWQGYLTKETNILRKRRLK---------PKHKDFEMITXXXXXXXX 184
Q SN+ T+ I N LT L L P KD++++
Sbjct: 750 QHPSNIARTDSINN---AMLTSPNMPLSPLLLATNQTVKSPTPSIKDYDILKPISKGAYG 806
Query: 185 XXXLARKKDTKEICAXXXXXXXXXXXXEGTDHVLTERDILTTTRSE-WLVKLLYAFQDPQ 243
LARKK T + A +V +ER I+ + ++ +L +FQ+
Sbjct: 807 SVYLARKKLTGDYFAIKVLRKSDMIAKNQVTNVKSERAIMMVQSDKPYVARLFASFQNKD 866
Query: 244 SLYLAMEFVPGGDFRTLLLNTKFLQAPHARFYISEMFCAVNALHQLGYTHRDLKPENFLI 303
+L+L ME++PGGD TL+ +L A+ Y++E+ VN +HQ G H DLKPEN LI
Sbjct: 867 NLFLVMEYLPGGDLATLIKMMGYLPDQWAKQYLTEIVVGVNDMHQNGIIHHDLKPENLLI 926
Query: 304 DSKGHIKLTDFGLA 317
D+ GH+KLTDFGL+
Sbjct: 927 DNAGHVKLTDFGLS 940
Score = 82.0 bits (201), Expect = 2e-15
Identities = 48/137 (35%), Positives = 74/137 (53%), Gaps = 9/137 (6%)
Query: 372 GSPDYMALEVLEAKNYDFT-VDYWSLGCILFESLVGYTPFSGNSTNETYENLRNWKHVLQ 430
G+PDY+A E +E K D D+WS+GCI FE L+GY PF + + ++ + + V+Q
Sbjct: 1149 GTPDYLAPETIEGKGEDNKQCDWWSVGCIFFELLLGYPPFHAETPDAVFKKILS--GVIQ 1206
Query: 431 RPKCDN---GRYAFSDRTWELITR-LIADPINRL--KSFEHVKRMRYFSEIDFNTLRTIH 484
P+ N R + +LI + L+ DP RL K + +K YF +D++ +
Sbjct: 1207 WPEFKNEEEEREFLTPEAKDLIEKLLVVDPAKRLGAKGIQEIKDHPYFKNVDWDHVYDEE 1266
Query: 485 PPFIPQLDNEEDVGYFD 501
F+P +DN ED YFD
Sbjct: 1267 ASFVPTIDNPEDTDYFD 1283
>Hs4506529 [T] KOG0986 G protein-coupled receptor kinase
Length = 563
Score = 103 bits (257), Expect = 7e-22
Identities = 81/304 (26%), Positives = 137/304 (44%), Gaps = 58/304 (19%)
Query: 212 EGTDHVLTERDILTTTRSEWLVKLLYAFQDPQSLYLAMEFVPGGDFRTLLLNTKF----L 267
+G + E+ IL S ++V L YAF+ L L M + GGD R + N
Sbjct: 230 KGYQGAMVEKKILMKVHSRFIVSLAYAFETKADLCLVMTIMNGGDIRYHIYNVNEENPGF 289
Query: 268 QAPHARFYISEMFCAVNALHQLGYTHRDLKPENFLIDSKGHIKLTDFGLASGTVSMERIE 327
P A FY +++ C + LHQ +RDLKPEN L+D+ G+++++D GLA +E ++
Sbjct: 290 PEPRALFYTAQIICGLEHLHQRRIVYRDLKPENVLLDNDGNVRISDLGLA-----VELLD 344
Query: 328 SMKIRLQEVKNLEFPEFRERSMDDRRRMYNKLREEEVRYAHSTVGSPDYMALEVLEAKNY 387
+ + YA G+P +MA E+L+ + Y
Sbjct: 345 G-------------------------------QSKTKGYA----GTPGFMAPELLQGEEY 369
Query: 388 DFTVDYWSLGCILFESLVGYTPFSGNSTNETYENLRNWKHVLQRPKCDNGRYAFSDRTWE 447
DF+VDY++LG L+E + PF + E EN ++ P +++ + + +
Sbjct: 370 DFSVDYFALGVTLYEMIAARGPF--RARGEKVENKELKHRIISEPVKYPDKFSQASKDF- 426
Query: 448 LITRLIADPINRL----KSFEHVKRMRYFSEIDFNTLRT--IHPPFIPQ-----LDNEED 496
L DP RL ++ + ++ F ++++ L + PPFIP + +D
Sbjct: 427 CEALLEKDPEKRLGFRDETCDKLRAHPLFKDLNWRQLEAGMLMPPFIPDSKTVYAKDIQD 486
Query: 497 VGYF 500
VG F
Sbjct: 487 VGAF 490
>At3g12690 [R] KOG0610 Putative serine/threonine protein kinase
Length = 577
Score = 103 bits (257), Expect = 7e-22
Identities = 85/300 (28%), Positives = 136/300 (45%), Gaps = 34/300 (11%)
Query: 219 TERDILTTTRSEWLVKLLYAFQDPQSLYLAMEFVPGGDFRTLLLN--TKFLQAPHARFYI 276
TER+IL+ +L L F+ + L MEF GG+ +L ++ ARFY
Sbjct: 232 TEREILSLLDHPFLPTLYSYFETDKFYCLVMEFCSGGNLHSLRQKQPSRRFTEEAARFYA 291
Query: 277 SEMFCAVNALHQLGYTHRDLKPENFLIDSKGHIKLTDFGLA---SGTVSMERIESMKIRL 333
SE+ A+ LH LG +RDLKPEN L+ +GHI L+DF L+ + ++ + S+
Sbjct: 292 SEVLLALEYLHMLGVVYRDLKPENILVRDEGHIMLSDFDLSLRCTFNPTLVKSSSVCSGG 351
Query: 334 QEVKNLEF--------PEFRERSMDDRR-------------RMYNKLREEEVRYAHSTVG 372
+ N EF F R + ++ M + E + S VG
Sbjct: 352 GAILNEEFAVNGCMHPSAFLPRLLPSKKTRKAKSDSGLGGLSMPELMAEPTDVRSMSFVG 411
Query: 373 SPDYMALEVLEAKNYDFTVDYWSLGCILFESLVGYTPFSGNSTNETYENLRNWKHVLQRP 432
+ +Y+A E++ + + VD+W+ G L+E L G TPF G T N+ L+ P
Sbjct: 412 THEYLAPEIIRGEGHGSAVDWWTFGIFLYELLHGTTPFKGQGNRATLHNVVG--QPLKFP 469
Query: 433 KCDNGRYAFSDRTWELITRLIADPINRL---KSFEHVKRMRYFSEIDFNTLRTIHPPFIP 489
+ A D L L+ DP R+ + +K+ +F +++ +R+ PP IP
Sbjct: 470 DTPHVSSAARDLIRGL---LVKDPHRRIAYTRGATEIKQHPFFEGVNWALVRSAAPPHIP 526
>SPBC4C3.11 [T] KOG0592 3-phosphoinositide-dependent protein kinase (PDK1)
Length = 420
Score = 103 bits (256), Expect = 9e-22
Identities = 62/253 (24%), Positives = 112/253 (43%), Gaps = 41/253 (16%)
Query: 234 KLLYAFQDPQSLYLAMEFVPGGDFRTLLLNTKFLQAPHARFYISEMFCAVNALHQLGYTH 293
+L + FQD LY +E P G+ + +FL RFY +E+ ++ +H G H
Sbjct: 117 RLFHTFQDDLKLYYVLELAPNGELLQYIKKYRFLDENCVRFYAAEILSSIEYMHSCGIIH 176
Query: 294 RDLKPENFLIDSKGHIKLTDFGLASGTVSMERIESMKIRLQEVKNLEFPEFRERSMDDRR 353
RDLKPEN L D H+K+TDFG A ++ K + P++
Sbjct: 177 RDLKPENILFDGNMHVKITDFGTA--------------KILPPKYVNSPDY--------- 213
Query: 354 RMYNKLREEEVRYAHSTVGSPDYMALEVLEAKNYDFTVDYWSLGCILFESLVGYTPFSGN 413
+ S VG+ +Y+A E+L + + D W+ C++++ +VG PF G+
Sbjct: 214 ----------TTFPSSFVGTAEYVAPELLSRQVVSKSSDLWAFACVVYQMIVGSPPFHGS 263
Query: 414 STNETYENLRNWKHVLQRPKCDNGRYAFSDRTWELITRLIADPINRLKSFEHVKRMRYFS 473
+ N ++ + + ++ L + L + L + + + +K+ +F+
Sbjct: 264 NPNNIFKKIMSLEYELPK--------LLPPDIVPLFSHLFRIQPSDRSTTQQIKQFPFFA 315
Query: 474 EIDFNTLRTIHPP 486
I ++ L T PP
Sbjct: 316 TITWDNLWTQDPP 328
>At5g35410 [T] KOG0583 Serine/threonine protein kinase
Length = 446
Score = 103 bits (256), Expect = 9e-22
Identities = 68/235 (28%), Positives = 99/235 (41%), Gaps = 41/235 (17%)
Query: 189 ARKKDTKEICAXXXXXXXXXXXXEGTDHVLTERDILTTTRSEWLVKLLYAFQDPQSLYLA 248
AR DT + A D + E I+ R +V+L P +Y+
Sbjct: 28 ARNTDTGDNVAIKIMAKSTILKNRMVDQIKREISIMKIVRHPNIVRLYEVLASPSKIYIV 87
Query: 249 MEFVPGGDFRTLLLNTKFLQAPHARFYISEMFCAVNALHQLGYTHRDLKPENFLIDSKGH 308
+EFV GG+ +++ L+ +R Y ++ AV H G HRDLKPEN L+D+ G+
Sbjct: 88 LEFVTGGELFDRIVHKGRLEESESRKYFQQLVDAVAHCHCKGVYHRDLKPENLLLDTNGN 147
Query: 309 IKLTDFGLASGTVSMERIESMKIRLQEVKNLEFPEFRERSMDDRRRMYNKLREEEVRYAH 368
+K++DFGL++ L +E V
Sbjct: 148 LKVSDFGLSA----------------------------------------LPQEGVELLR 167
Query: 369 STVGSPDYMALEVLEAKNYD-FTVDYWSLGCILFESLVGYTPFSGNSTNETYENL 422
+T G+P+Y+A EVL + YD D WS G ILF L GY PFS Y +
Sbjct: 168 TTCGTPNYVAPEVLSGQGYDGSAADIWSCGVILFVILAGYLPFSETDLPGLYRKI 222
>At1g79250 [R] KOG0610 Putative serine/threonine protein kinase
Length = 517
Score = 103 bits (256), Expect = 9e-22
Identities = 82/308 (26%), Positives = 136/308 (43%), Gaps = 38/308 (12%)
Query: 219 TERDILTTTRSEWLVKLLYAFQDPQSLYLAMEFVPGGDFRTLLLN--TKFLQAPHARFYI 276
TER+IL+ +L L F+ + L MEF GG+ +L K ARF+
Sbjct: 155 TEREILSQLDHPFLPTLYSHFETDKFYCLVMEFCGGGNLYSLRQKQPNKCFTEDAARFFA 214
Query: 277 SEMFCAVNALHQLGYTHRDLKPENFLIDSKGHIKLTDFGLA-SGTVSMERIESMKIR--- 332
SE+ A+ LH LG +RDLKPEN L+ GHI L+DF L+ +VS ++S +
Sbjct: 215 SEVLLALEYLHMLGIVYRDLKPENVLVRDDGHIMLSDFDLSLRCSVSPTLVKSSSVHAAG 274
Query: 333 -----------LQEVKNLE--------FPEFRERSMDDRR-----------RMYNKLREE 362
+ E ++ FP + S +R+ M + E
Sbjct: 275 GGSGSSRPVGLIDEDAAVQGCIQPSTFFPRILQSSKKNRKAKSDFGLFVNGSMPELMAEP 334
Query: 363 EVRYAHSTVGSPDYMALEVLEAKNYDFTVDYWSLGCILFESLVGYTPFSGNSTNETYENL 422
+ S VG+ +Y+A E++ + + VD+W+ G ++E L G TPF G T N+
Sbjct: 335 TNVKSMSFVGTHEYLAPEIIRGEGHGSAVDWWTFGIFIYELLYGATPFKGQGNRATLHNV 394
Query: 423 RNWKHVLQRPKCDNGRYAFSDRTWELITRLIADPINRLKSFEHVKRMRYFSEIDFNTLRT 482
L+ P+ + A D L+ + I + +K+ +F +++ +R+
Sbjct: 395 IG--QALRFPEVPHVSSAARDLIKGLLVKEPQKRIAYKRGATEIKQHPFFEGVNWALIRS 452
Query: 483 IHPPFIPQ 490
PP +P+
Sbjct: 453 ATPPHVPE 460
>Hs22068916 [T] KOG0696 Serine/threonine protein kinase
Length = 673
Score = 102 bits (254), Expect = 2e-21
Identities = 87/349 (24%), Positives = 143/349 (40%), Gaps = 61/349 (17%)
Query: 155 KETNILRK-----RRLKPKHKDFEMITXXXXXXXXXXXLARKKDTKEICAXXXXXXXXXX 209
K TN + K R + K DF + L+ +K T E+ A
Sbjct: 320 KTTNTVSKFDNNGNRDRMKLTDFNFLMVLGKGSFGKVMLSERKGTDELYAVKILKKDVVI 379
Query: 210 XXEGTDHVLTERDILTTT-RSEWLVKLLYAFQDPQSLYLAMEFVPGGDFRTLLLNTKFLQ 268
+ + + E+ +L + +L +L FQ LY ME+V GGD + +
Sbjct: 380 QDDDVECTMVEKRVLALPGKPPFLTQLHSCFQTMDRLYFVMEYVNGGDLMYHIQQVGRFK 439
Query: 269 APHARFYISEMFCAVNALHQLGYTHRDLKPENFLIDSKGHIKLTDFGLASGTVSMERIES 328
PHA FY +E+ + L G +RDLK +N ++DS+GHIK+ DFG+
Sbjct: 440 EPHAVFYAAEIAIGLFFLQSKGIIYRDLKLDNVMLDSEGHIKIADFGMC----------- 488
Query: 329 MKIRLQEVKNLEFPEFRERSMDDRRRMYNKLREEEVRYAHSTVGSPDYMALEVLEAKNYD 388
+E D + G+PDY+A E++ + Y
Sbjct: 489 ----------------KENIWDGVT-------------TKTFCGTPDYIAPEIIAYQPYG 519
Query: 389 FTVDYWSLGCILFESLVGYTPFSGNSTNETYENLRNWKHVLQRPKCDNGRYAFSDRTWEL 448
+VD+W+ G +L+E L G PF G +E ++++ +H + PK + S +
Sbjct: 520 KSVDWWAFGVLLYEMLAGQAPFEGEDEDELFQSI--MEHNVAYPK------SMSKEAVAI 571
Query: 449 ITRLIA-DPINRL----KSFEHVKRMRYFSEIDFNTL--RTIHPPFIPQ 490
L+ P RL + +K +F ID+ L + I PP+ P+
Sbjct: 572 CKGLMTKHPGKRLGCGPEGERDIKEHAFFRYIDWEKLERKEIQPPYKPK 620
>Hs20127450 [T] KOG0696 Serine/threonine protein kinase
Length = 673
Score = 102 bits (254), Expect = 2e-21
Identities = 87/349 (24%), Positives = 143/349 (40%), Gaps = 61/349 (17%)
Query: 155 KETNILRK-----RRLKPKHKDFEMITXXXXXXXXXXXLARKKDTKEICAXXXXXXXXXX 209
K TN + K R + K DF + L+ +K T E+ A
Sbjct: 320 KTTNTVSKFDNNGNRDRMKLTDFNFLMVLGKGSFGKVMLSERKGTDELYAVKILKKDVVI 379
Query: 210 XXEGTDHVLTERDILTTT-RSEWLVKLLYAFQDPQSLYLAMEFVPGGDFRTLLLNTKFLQ 268
+ + + E+ +L + +L +L FQ LY ME+V GGD + +
Sbjct: 380 QDDDVECTMVEKRVLALPGKPPFLTQLHSCFQTMDRLYFVMEYVNGGDLMYHIQQVGRFK 439
Query: 269 APHARFYISEMFCAVNALHQLGYTHRDLKPENFLIDSKGHIKLTDFGLASGTVSMERIES 328
PHA FY +E+ + L G +RDLK +N ++DS+GHIK+ DFG+
Sbjct: 440 EPHAVFYAAEIAIGLFFLQSKGIIYRDLKLDNVMLDSEGHIKIADFGMC----------- 488
Query: 329 MKIRLQEVKNLEFPEFRERSMDDRRRMYNKLREEEVRYAHSTVGSPDYMALEVLEAKNYD 388
+E D + G+PDY+A E++ + Y
Sbjct: 489 ----------------KENIWDGVT-------------TKTFCGTPDYIAPEIIAYQPYG 519
Query: 389 FTVDYWSLGCILFESLVGYTPFSGNSTNETYENLRNWKHVLQRPKCDNGRYAFSDRTWEL 448
+VD+W+ G +L+E L G PF G +E ++++ +H + PK + S +
Sbjct: 520 KSVDWWAFGVLLYEMLAGQAPFEGEDEDELFQSI--MEHNVAYPK------SMSKEAVAI 571
Query: 449 ITRLIA-DPINRL----KSFEHVKRMRYFSEIDFNTL--RTIHPPFIPQ 490
L+ P RL + +K +F ID+ L + I PP+ P+
Sbjct: 572 CKGLMTKHPGKRLGCGPEGERDIKEHAFFRYIDWEKLERKEIQPPYKPK 620
>7291910 [T] KOG0592 3-phosphoinositide-dependent protein kinase (PDK1)
Length = 755
Score = 102 bits (254), Expect = 2e-21
Identities = 85/326 (26%), Positives = 142/326 (43%), Gaps = 59/326 (18%)
Query: 215 DHVLTERDIL-TTTRSEWLVKLLYAFQDPQSLYLAMEFVPGGDFRTLLLNTKFLQAPHAR 273
D++ ER+++ T V L FQD +SLY M + GD + R
Sbjct: 208 DYIKREREVMHQMTNVPGFVNLSCTFQDQRSLYFVMTYARKGDMLPYINRVGSFDVACTR 267
Query: 274 FYISEMFCAVNALHQLGYTHRDLKPENFLIDSKGHIKLTDFGLASGTVSMERI------- 326
Y +E+ A +H+ HRDLKPEN L+D H + DFG A + ER
Sbjct: 268 HYAAELLLACEHMHRRNVVHRDLKPENILLDEDMHTLIADFGSAKVMTAHERALATEHCS 327
Query: 327 ----------ESMKIRLQEVKNLEFPEFRERSMDD---------------RRRMYNKLRE 361
+ RL E ++ +F + +DD R+R YN+ R+
Sbjct: 328 EQRRSNSDEDDEDSDRL-ENEDEDFYDRDSEELDDGDDEQQQEEMDSPRHRQRRYNRHRK 386
Query: 362 EEVRYAHSTVGSPDYMALEVLEAKNYDFTVDYWSLGCILFESLVGYTPFSGNSTNETYEN 421
S VG+ Y++ EVL+ D W+LGCI+++ + G PF G++ ++
Sbjct: 387 A------SFVGTAQYVSPEVLQNGPITPAADLWALGCIVYQMIAGLPPFRGSNDYVIFKE 440
Query: 422 LRNWKHVLQRPKCDNGRYAFSDRTWELITRLI-ADPINRLKS------FEHVKRMRYFSE 474
+ + + P+ F +L+ +L+ DP +RL + +E ++ +F+
Sbjct: 441 ILDC--AVDFPQ------GFDKDAEDLVRKLLRVDPRDRLGAQDEFGYYESIRAHPFFAG 492
Query: 475 IDFNTLRTIHP----PFIPQLDNEED 496
ID+ TLR P P++P + +ED
Sbjct: 493 IDWQTLRQQTPPPIYPYLPGVSQDED 518
>Hs4501971 [T] KOG0986 G protein-coupled receptor kinase
Length = 689
Score = 101 bits (251), Expect = 3e-21
Identities = 84/330 (25%), Positives = 140/330 (41%), Gaps = 65/330 (19%)
Query: 190 RKKDTKEICAXXXXXXXXXXXXEGTDHVLTER---DILTTTRSEWLVKLLYAFQDPQSLY 246
RK+DT ++ A +G L ER +++T ++V + YAF P L
Sbjct: 209 RKRDTGKMYAMKCLDKKRIKMKQGETLALNERIMLSLVSTGDCPFIVCMSYAFHTPDKLS 268
Query: 247 LAMEFVPGGDFRTLLLNTKFLQAPHARFYISEMFCAVNALHQLGYTHRDLKPENFLIDSK 306
++ + GGD L RFY +E+ + +H +RDLKP N L+D
Sbjct: 269 FILDLMNGGDLHYHLSQHGVFSEADMRFYAAEIILGLEHMHNRFVVYRDLKPANILLDEH 328
Query: 307 GHIKLTDFGLASGTVSMERIESMKIRLQEVKNLEFPEFRERSMDDRRRMYNKLREEEVRY 366
GH++++D GLA +F ++
Sbjct: 329 GHVRISDLGLAC------------------------DFSKKK------------------ 346
Query: 367 AHSTVGSPDYMALEVLE-AKNYDFTVDYWSLGCILFESLVGYTPFSGNSTNETYE-NLRN 424
H++VG+ YMA EVL+ YD + D++SLGC+LF+ L G++PF + T + +E +
Sbjct: 347 PHASVGTHGYMAPEVLQKGVAYDSSADWFSLGCMLFKLLRGHSPFRQHKTKDKHEIDRMT 406
Query: 425 WKHVLQRPKCDNGRYAFSDRTWELITRLIADPINRL-----KSFEHVKRMRYFSEIDFNT 479
++ P +FS L+ L+ +NR + + VK +F +D+
Sbjct: 407 LTMAVELPD------SFSPELHSLLEGLLQRDVNRRLGCLGRGAQEVKESPFFRSLDWQM 460
Query: 480 --LRTIHPPFIP-----QLDNEEDVGYFDD 502
L+ PP IP + D+G FD+
Sbjct: 461 VFLQRYPPPLIPPRGEVNAADAFDIGSFDE 490
>CE18699 [T] KOG0694 Serine/threonine protein kinase
Length = 1018
Score = 100 bits (249), Expect = 6e-21
Identities = 80/298 (26%), Positives = 135/298 (44%), Gaps = 63/298 (21%)
Query: 222 DILTTTRSEWLVKLLYAFQDPQSLYLAMEFVPGGDFRTLLLNTKFLQAPHARFYISEMFC 281
++ + R +LV L FQ + ++ ME+ GGD + + F + FY + +
Sbjct: 743 EVSSRARHPFLVNLNGCFQTNEHVFFCMEYSMGGDLMRHIHDDVFDEV-RGCFYAACVVL 801
Query: 282 AVNALHQLGYTHRDLKPENFLIDSKGHIKLTDFGLASGTVSMERIESMKIRLQEVKNLEF 341
++ LH+ +RD+K +N L+D +G++K+ DFGL +
Sbjct: 802 GLDFLHKHNIIYRDIKLDNLLLDREGYVKIADFGLCKENMG------------------- 842
Query: 342 PEFRERSMDDRRRMYNKLREEEVRYAHSTVGSPDYMALEVLEAKNYDFTVDYWSLGCILF 401
F + S + G+P+++A EVL +Y +D+W LG ++F
Sbjct: 843 -PFDKTS--------------------TFCGTPEFLAPEVLSDSSYTRAIDWWGLGVLIF 881
Query: 402 ESLVGYTPFSGNSTNETYENLRNWKHVLQRPKCDNGRYA--FSDRTWELITRLIAD-PIN 458
E LVG PFSG+ E ++++ + ++ RY S + ++ RL+ P
Sbjct: 882 EMLVGEPPFSGDDEEEIFDSIIS----------EDVRYPRYLSVESIAIMRRLLRKVPEK 931
Query: 459 RL----KSFEHVKRMRYFSEIDFN----TLRTIHPPFIPQLDNEEDVGYFD-DFTNEE 507
RL + E +K R+F I + R I PPF PQ+ N EDV FD +FT E+
Sbjct: 932 RLGYGERDAEDIKIQRFFRHISWEWDKLLNREIRPPFQPQIRNPEDVSNFDLEFTQEK 989
>Hs4505695 [T] KOG0592 3-phosphoinositide-dependent protein kinase (PDK1)
Length = 556
Score = 100 bits (248), Expect = 8e-21
Identities = 81/353 (22%), Positives = 142/353 (39%), Gaps = 58/353 (16%)
Query: 166 KPKHKDFEMITXXXXXXXXXXXLARKKDTKEICAXXXXXXXXXXXXEGTDHVLTERDILT 225
K + +DF+ LAR+ T A +V ERD+++
Sbjct: 76 KKRPEDFKFGKILGEGSFSTVVLARELATSREYAIKILEKRHIIKENKVPYVTRERDVMS 135
Query: 226 TTRSEWLVKLLYAFQDPQSLYLAMEFVPGGDFRTLLLNTKFLQAPHARFYISEMFCAVNA 285
+ VKL + FQD + LY + + G+ + RFY +E+ A+
Sbjct: 136 RLDHPFFVKLYFTFQDDEKLYFGLSYAKNGELLKYIRKIGSFDETCTRFYTAEIVSALEY 195
Query: 286 LHQLGYTHRDLKPENFLIDSKGHIKLTDFGLASGTVSMERIESMKIRLQEVKNLEFPEFR 345
LH G HRDLKPEN L++ HI++TDFG A K+ E K
Sbjct: 196 LHGKGIIHRDLKPENILLNEDMHIQITDFGTA------------KVLSPESKQAR----- 238
Query: 346 ERSMDDRRRMYNKLREEEVRYAHSTVGSPDYMALEVLEAKNYDFTVDYWSLGCILFESLV 405
A+S VG+ Y++ E+L K+ + D W+LGCI+++ +
Sbjct: 239 ---------------------ANSFVGTAQYVSPELLTEKSACKSSDLWALGCIIYQLVA 277
Query: 406 GYTPFSGNSTNETYENLRNWKHVLQRPKCDNGRYAFSDRTWELITR-LIADPINRL---- 460
G PF + ++ + ++ F + +L+ + L+ D RL
Sbjct: 278 GLPPFRAGNEYLIFQKIIKLEYDFPE--------KFFPKARDLVEKLLVLDATKRLGCEE 329
Query: 461 -KSFEHVKRMRYFSEIDFNTLRTIHPP----FIPQL--DNEEDVGYFDDFTNE 506
+ + +K +F + + L PP ++P + D+E+ G +D+ ++
Sbjct: 330 MEGYGPLKAHPFFESVTWENLHQQTPPKLTAYLPAMSEDDEDCYGNYDNLLSQ 382
>At1g16440 [R] KOG0610 Putative serine/threonine protein kinase
Length = 431
Score = 100 bits (248), Expect = 8e-21
Identities = 82/300 (27%), Positives = 136/300 (45%), Gaps = 35/300 (11%)
Query: 219 TERDILTTTRSEWLVKLLYAFQDPQSLYLAMEFVPGGDFRTLLLN--TKFLQAPHARFYI 276
TER+IL+ +L L F+ + L MEF GG+ +L K ARF+
Sbjct: 94 TEREILSQLDHPFLPTLYSHFETDKFYCLVMEFCSGGNLYSLRQKQPNKCFTEDAARFFA 153
Query: 277 SEMFCAVNALHQLGYTHRDLKPENFLIDSKGHIKLTDFGLA---------------SGTV 321
SE+ A+ LH LG +RDLKPEN L+ GHI L+DF L+ GT
Sbjct: 154 SEVLLALEYLHMLGIVYRDLKPENVLVRDDGHIMLSDFDLSLRCSVNPTLVKSFNGGGTT 213
Query: 322 SMERIESMKIRLQEVKNLEFPEFRERSMDDRR-------RMYNKLREEEVRYAHSTVGSP 374
+ ++ ++ + FP + S +R+ + + E + S VG+
Sbjct: 214 GIID-DNAAVQGCYQPSAFFPRMLQSSKKNRKSKSDFDGSLPELMAEPTNVKSMSFVGTH 272
Query: 375 DYMALEVLEAKNYDFTVDYWSLGCILFESLVGYTPFSGNSTNETYENLRNWKHVLQRPKC 434
+Y+A E+++ + + VD+W+ G ++E L G TPF G T N V+ +P
Sbjct: 273 EYLAPEIIKNEGHGSAVDWWTFGIFIYELLHGATPFKGQGNKATLYN------VIGQPLR 326
Query: 435 DNGRYAFSDRTWELIT-RLIADPINRL---KSFEHVKRMRYFSEIDFNTLRTIHPPFIPQ 490
S +LI L+ +P NR+ + +K+ +F +++ +R PP +P+
Sbjct: 327 FPEYSQVSSTAKDLIKGLLVKEPQNRIAYKRGATEIKQHPFFEGVNWALIRGETPPHLPE 386
>CE28739 [T] KOG0592 3-phosphoinositide-dependent protein kinase (PDK1)
Length = 632
Score = 98.6 bits (244), Expect = 2e-20
Identities = 77/286 (26%), Positives = 126/286 (43%), Gaps = 31/286 (10%)
Query: 215 DHVLTERDILTTTRSE-----WLVKLLYAFQDPQSLYLAMEFVPGGDFRTLLLNTKFLQA 269
D ++ E++ILT E ++ +L F D +Y + V GD L +
Sbjct: 112 DAIIREKNILTYLSQECGGHPFVTQLYTHFHDQARIYFVIGLVENGDLGESLCHFGSFDM 171
Query: 270 PHARFYISEMFCAVNALHQLGYTHRDLKPENFLIDSKGHIKLTDFGLASGTVSMERIESM 329
++F+ SE+ + LH HRD+KP+N LI GHI +TDFG A ++
Sbjct: 172 LTSKFFASEILTGLQFLHDNKIVHRDMKPDNVLIQKDGHILITDFGSAQAFGGLQ----- 226
Query: 330 KIRLQEVKNLEFPEFRERSMDD----RRRMYNKLREEEVRYAHSTVGSPDYMALEVLEAK 385
L + + + RS D R Y+ EE + VG+ Y++ E+L
Sbjct: 227 ---LSQEGFTDANQASSRSSDSGSPPPTRFYSDEEEENTARRTTFVGTALYVSPEMLADG 283
Query: 386 NYDFTVDYWSLGCILFESLVGYTPFSGNSTNETYENLRNWKHVLQRPKCDNGRY--AFSD 443
+ D W LGCILF+ L G PF N H+L+R + + + F +
Sbjct: 284 DVGPQTDIWGLGCILFQCLAGQPPF----------RAVNQYHLLKRIQELDFSFPEGFPE 333
Query: 444 RTWELITR-LIADPINRLKSFEHVKRMRYFSEIDFNTLRTIHPPFI 488
E+I + L+ DP R+ S + + ++F +D+ + I PP +
Sbjct: 334 EASEIIAKILVRDPSTRITS-QELMAHKFFENVDWVNIANIKPPVL 378
>CE02074 [T] KOG0986 G protein-coupled receptor kinase
Length = 727
Score = 98.6 bits (244), Expect = 2e-20
Identities = 87/327 (26%), Positives = 139/327 (41%), Gaps = 57/327 (17%)
Query: 190 RKKDTKEICAXXXXXXXXXXXXEGTDHVLTERDILTTTRS----EWLVKLLYAFQDPQSL 245
RK DT ++ A +G L ER +L+ + ++V + YAFQ P L
Sbjct: 209 RKADTGKMYAMKCLDKKRIKMKQGETLALNERIMLSLVSTGQDCPFIVCMTYAFQSPDKL 268
Query: 246 YLAMEFVPGGDFRTLLLNTKFLQAPHARFYISEMFCAVNALHQLGYTHRDLKPENFLIDS 305
++ + GGD L FY SE+ + +H +RDLKP N L+D
Sbjct: 269 CFILDLMNGGDLHYHLSQHGVFTEQEMIFYASEVILGLEHMHNRFVVYRDLKPANILLDE 328
Query: 306 KGHIKLTDFGLASGTVSMERIESMKIRLQEVKNLEFPEFRERSMDDRRRMYNKLREEEVR 365
GH++++D GLA Y+K +
Sbjct: 329 NGHVRVSDLGLACD------------------------------------YSK------K 346
Query: 366 YAHSTVGSPDYMALEVL-EAKNYDFTVDYWSLGCILFESLVGYTPFSGNSTNETYE-NLR 423
H++VG+ YMA EVL + YD + D++SLGC+L++ L G++PF + + + E +
Sbjct: 347 KPHASVGTHGYMAPEVLAKGVAYDSSADWFSLGCMLYKLLKGHSPFRQHKSKDKNEIDKM 406
Query: 424 NWKHVLQRPKCDNGRYAFSDRTWELITRLIADPIN-RLKSFEHVKRMRYFSEIDFNT--L 480
++ P + D L+ R + D + R K VK +F ++D+ T L
Sbjct: 407 TLTQDIELPN-EGLSKDCRDLLEGLLKRDVPDRLGCRGKGPTEVKEHPFFKDVDWQTVYL 465
Query: 481 RTIHPPFIP-----QLDNEEDVGYFDD 502
R + PP IP + D+G FDD
Sbjct: 466 RRMTPPLIPPRGEVNAADAFDIGNFDD 492
>7297611 [T] KOG0614 cGMP-dependent protein kinase
Length = 1003
Score = 98.6 bits (244), Expect = 2e-20
Identities = 73/294 (24%), Positives = 128/294 (42%), Gaps = 55/294 (18%)
Query: 215 DHVLTERDILTTTR-SEWLVKLLYAFQDPQSLYLAMEFVPGGDFRTLLLNTKFLQAPHAR 273
+HV E++++ R S ++V+L +++ + +Y ME GGD T++ ++ A+
Sbjct: 735 EHVYNEKNVMIKCRQSPFIVQLYRTYRNDKYVYFLMEACMGGDVWTVMSKRQYFDEKTAK 794
Query: 274 FYISEMFCAVNALHQLGYTHRDLKPENFLIDSKGHIKLTDFGLASGTVSMERIESMKIRL 333
F + A + LH + +RDLKPEN ++ + G+ KL DFG A E+
Sbjct: 795 FIAGCVVEAFDYLHSHHFIYRDLKPENLMLGTDGYCKLVDFGFAKFVRQNEK-------- 846
Query: 334 QEVKNLEFPEFRERSMDDRRRMYNKLREEEVRYAHSTVGSPDYMALEVLEAKNYDFTVDY 393
++ G+P+Y+A E++ + +D VDY
Sbjct: 847 ---------------------------------TNTFAGTPEYVAPEIILDRGHDRAVDY 873
Query: 394 WSLGCILFESLVGYTPFSGNSTNETYENLRNWKHVLQRPKCDNGRYAFSDRTWELITRLI 453
W+LG +++E LVG TPF G + + Y+ + + V+ P L+ L
Sbjct: 874 WALGILVYELLVGKTPFRGVNQIKIYQQILSGIDVIHMPS------RIPKSAQHLVRHLC 927
Query: 454 AD-PINRL----KSFEHVKRMRYFSEIDFN--TLRTIHPPFIPQLDNEEDVGYF 500
P RL K +KR +F +D+ L+ + P L + D+ YF
Sbjct: 928 KQLPAERLGYQRKGIADIKRHSWFESLDWQRLKLKQLPSPIKRPLKSWTDLQYF 981
>Hs14249562 [TR] KOG0606 Microtubule-associated serine/threonine kinase and
related proteins
Length = 878
Score = 96.7 bits (239), Expect = 9e-20
Identities = 49/111 (44%), Positives = 72/111 (64%)
Query: 214 TDHVLTERDILTTTRSEWLVKLLYAFQDPQSLYLAMEFVPGGDFRTLLLNTKFLQAPHAR 273
T V ERD L ++S ++V L Y+ Q ++YL ME++ GGD ++LL + A
Sbjct: 75 THQVQAERDALALSKSPFIVHLYYSLQSANNVYLVMEYLIGGDVKSLLHIYGYFDEEMAV 134
Query: 274 FYISEMFCAVNALHQLGYTHRDLKPENFLIDSKGHIKLTDFGLASGTVSME 324
YISE+ A++ LH+ G HRDLKP+N LI ++GHIKLTDFGL+ T++ +
Sbjct: 135 KYISEVALALDYLHRHGIIHRDLKPDNMLISNEGHIKLTDFGLSKVTLNRD 185
Score = 78.6 bits (192), Expect = 2e-14
Identities = 43/139 (30%), Positives = 72/139 (50%), Gaps = 5/139 (3%)
Query: 371 VGSPDYMALEVLEAKNYDFTVDYWSLGCILFESLVGYTPFSGNSTNETYENLRNWKHVLQ 430
+G+PDY+A E+L + + VD+W+LG LFE L G PF+ + + ++N+ K +
Sbjct: 738 LGTPDYLAPELLLGRAHGPAVDWWALGVCLFEFLTGIPPFNDETPQQVFQNI--LKRDIP 795
Query: 431 RPKCDNGRYAFSDRTWELITRLIADPINRLKSFEHVKRMRYFSEIDFNTLRTIHPPFIPQ 490
P+ G SD + L+ + + +KR FS++D+ L+ PFIPQ
Sbjct: 796 WPE---GEEKLSDNAQSAVEILLTIDDTKRAGMKELKRHPLFSDVDWENLQHQTMPFIPQ 852
Query: 491 LDNEEDVGYFDDFTNEEHM 509
D+E D YF+ +H+
Sbjct: 853 PDDETDTSYFETRNTAQHL 871
>CE03492 [RT] KOG0598 Ribosomal protein S6 kinase and related proteins
Length = 379
Score = 96.3 bits (238), Expect = 1e-19
Identities = 77/281 (27%), Positives = 122/281 (43%), Gaps = 52/281 (18%)
Query: 216 HVLTERDILTTTRSEWLVKLLYAFQDPQSLYLAMEFVPGGDFRTLLLNTKFLQAPHARFY 275
+V+ E +L+ ++V L Y FQD +Y+ + + GGD R L A+ Y
Sbjct: 72 NVIRELTLLSKMSHPFIVNLWYTFQDGDYMYMVSDLLLGGDLRYHLSQQGKFAEDRAKLY 131
Query: 276 ISEMFCAVNALHQLGYTHRDLKPENFLIDSKGHIKLTDFGLASGTVSMERIESMKIRLQE 335
+ E+ AV LH++ HRD+KPEN L+D +GH LTD LA+
Sbjct: 132 LCEICLAVEYLHEMKIVHRDIKPENILLDEQGHAHLTDLNLAT----------------- 174
Query: 336 VKNLEFPEFRERSMDDRRRMYNKLREEEVRYAHSTVGSPDYMALEV----LEAKN-YDFT 390
+L ++++ ++S G+ YMA E+ LE ++ YD
Sbjct: 175 ----------------------QLEDDQLATSYS--GTRPYMAPEIYATYLEIEDGYDSR 210
Query: 391 VDYWSLGCILFESLVGYTPFSGNSTNETYENLRNWKHVLQRPKCDNGRYAFSDRTWELIT 450
VD+W+LG +E L G TPF +S + E + + +D + +
Sbjct: 211 VDWWALGVCFYEMLRGRTPFEFSSRTKPEEAY----VAFRESSIPYPAHWPTDLIQFINS 266
Query: 451 RLIADPINRLKSFEHVKRMRYFSEIDFNTL--RTIHPPFIP 489
L D RL E +K+ Y IDF ++ + P FIP
Sbjct: 267 MLKFDKEKRLVGLEAIKKHSYTERIDFKSVFEKKPSPVFIP 307
>At1g29230 [T] KOG0583 Serine/threonine protein kinase
Length = 520
Score = 96.3 bits (238), Expect = 1e-19
Identities = 76/266 (28%), Positives = 117/266 (43%), Gaps = 61/266 (22%)
Query: 216 HVLTERDILTTTRSEWLVKLLYAFQDPQSLYLAMEFVPGGDFRTLLLNTKFLQAPHARFY 275
H+ E IL R ++V L +Y ME+V GG+ + + L AR Y
Sbjct: 118 HIKREISILRRVRHPYIVHLFEVMATKSKIYFVMEYVGGGELFNTVAKGR-LPEETARRY 176
Query: 276 ISEMFCAVNALHQLGYTHRDLKPENFLIDSKGHIKLTDFGLASGTVSMERIESMKIRLQE 335
++ +V+ H G HRDLKPEN L+D+KG++K++DFGL++
Sbjct: 177 FQQLISSVSFCHGRGVYHRDLKPENLLLDNKGNLKVSDFGLSA----------------- 219
Query: 336 VKNLEFPEFRERSMDDRRRMYNKLREEEVRYAHSTVGSPDYMALEVLEAKNYDFT-VDYW 394
+ +LR++ + H+ G+P Y+A EVL K YD D W
Sbjct: 220 -------------------VAEQLRQDGL--CHTFCGTPAYIAPEVLTRKGYDAAKADVW 258
Query: 395 SLGCILFESLVGYTPFSGNSTNETYENLRNWKHVLQRPKCDNGRYAFSDRTWELITRLI- 453
S G ILF + G+ PF + Y+ + +K + P+ FS L+TRL+
Sbjct: 259 SCGVILFVLMAGHIPFYDKNIMVMYKKI--YKGEFRCPRW------FSSDLVRLLTRLLD 310
Query: 454 ADPINRL------------KSFEHVK 467
+P R+ K F+HVK
Sbjct: 311 TNPDTRITIPEIMKNRWFKKGFKHVK 336
>Hs22042851 [T] KOG0986 G protein-coupled receptor kinase
Length = 266
Score = 95.9 bits (237), Expect = 1e-19
Identities = 83/282 (29%), Positives = 123/282 (43%), Gaps = 70/282 (24%)
Query: 254 GGD--FRTLLLNTKFLQAPHARFYISEMFCAVNALHQLGYTHRDLKPENFLIDSKGHIKL 311
GGD F L A FY +E+ C + L + +RDLKPEN L+D +GHI++
Sbjct: 3 GGDLKFHIYNLGNPGFDEQRAVFYAAELCCGLEDLQRERIVYRDLKPENILLDDRGHIRI 62
Query: 312 TDFGLASGTVSMERIESMKIRLQEVKNLEFPEFRERSMDDRRRMYNKLREEEVRYAHSTV 371
+D GLA+ E PE + VR TV
Sbjct: 63 SDLGLAT---------------------EIPE-----------------GQRVRGRVGTV 84
Query: 372 GSPDYMALEVLEAKNYDFTVDYWSLGCILFESLVGYTPFSGNSTNETYENLRNWKHVLQR 431
G YMA EV+ + Y F+ D+W LGC+++E + G++PF + Y+ W+ V QR
Sbjct: 85 G---YMAPEVVNNEKYTFSPDWWGLGCLIYEMIQGHSPF------KKYKEKVKWEEVDQR 135
Query: 432 PKCDNGRYA--FSDRTWELITRLIA-DPINRL----KSFEHVKRMRYFSEIDFNTLRT-- 482
K D Y+ FS+ + L+ +P RL + VK+ F +I+F L
Sbjct: 136 IKNDTEEYSEKFSEDAKSICRMLLTKNPSKRLGCRGEGAAGVKQHPVFKDINFRRLEANM 195
Query: 483 IHPPFIPQ---------LDNEE---DVGYFDDFTNEEHMARY 512
+ PPF P LD E+ G + D +E+ AR+
Sbjct: 196 LEPPFCPDPHAVYCKDVLDIEQFSAVKGIYLDTADEDFYARF 237
>At5g01810 [T] KOG0583 Serine/threonine protein kinase
Length = 421
Score = 95.5 bits (236), Expect = 2e-19
Identities = 65/210 (30%), Positives = 93/210 (43%), Gaps = 40/210 (19%)
Query: 214 TDHVLTERDILTTTRSEWLVKLLYAFQDPQSLYLAMEFVPGGDFRTLLLNTKFLQAPHAR 273
T+ + E + R +V+L +Y ME V GG+ + K L+ AR
Sbjct: 54 TEQIKREISAMRLLRHPNIVELHEVMATKSKIYFVMEHVKGGELFNKVSTGK-LREDVAR 112
Query: 274 FYISEMFCAVNALHQLGYTHRDLKPENFLIDSKGHIKLTDFGLASGTVSMERIESMKIRL 333
Y ++ AV+ H G HRDLKPEN L+D G++K++DFGL+
Sbjct: 113 KYFQQLVRAVDFCHSRGVCHRDLKPENLLLDEHGNLKISDFGLS---------------- 156
Query: 334 QEVKNLEFPEFRERSMDDRRRMYNKLREEEVRYAHSTVGSPDYMALEVLEAKNYD-FTVD 392
++ D RR L H+T G+P Y+A EV+ YD F D
Sbjct: 157 --------------ALSDSRRQDGLL--------HTTCGTPAYVAPEVISRNGYDGFKAD 194
Query: 393 YWSLGCILFESLVGYTPFSGNSTNETYENL 422
WS G ILF L GY PF ++ E Y+ +
Sbjct: 195 VWSCGVILFVLLAGYLPFRDSNLMELYKKI 224
>At2g26980 [T] KOG0583 Serine/threonine protein kinase
Length = 441
Score = 95.5 bits (236), Expect = 2e-19
Identities = 63/263 (23%), Positives = 116/263 (43%), Gaps = 39/263 (14%)
Query: 161 RKRRLKPKHKDFEMITXXXXXXXXXXXLARKKDTKEICAXXXXXXXXXXXXEGTDHVLTE 220
R++++K + +E+ AR +T E A + + + E
Sbjct: 3 RRQQVKRRVGKYEVGRTIGEGTFAKVKFARNSETGEPVALKILDKEKVLKHKMAEQIRRE 62
Query: 221 RDILTTTRSEWLVKLLYAFQDPQSLYLAMEFVPGGDFRTLLLNTKFLQAPHARFYISEMF 280
+ + +V+L +++ +E+V GG+ ++N ++ AR Y ++
Sbjct: 63 IATMKLIKHPNVVQLYEVMASKTKIFIILEYVTGGELFDKIVNDGRMKEDEARRYFQQLI 122
Query: 281 CAVNALHQLGYTHRDLKPENFLIDSKGHIKLTDFGLASGTVSMERIESMKIRLQEVKNLE 340
AV+ H G HRDLKPEN L+DS G++K++DFGL++
Sbjct: 123 HAVDYCHSRGVYHRDLKPENLLLDSYGNLKISDFGLSA---------------------- 160
Query: 341 FPEFRERSMDDRRRMYNKLREEEVRYAHSTVGSPDYMALEVLEAKNYD-FTVDYWSLGCI 399
+ ++R++ + H++ G+P+Y+A EVL + YD T D WS G +
Sbjct: 161 --------------LSQQVRDDGL--LHTSCGTPNYVAPEVLNDRGYDGATADMWSCGVV 204
Query: 400 LFESLVGYTPFSGNSTNETYENL 422
L+ L GY PF ++ Y+ +
Sbjct: 205 LYVLLAGYLPFDDSNLMNLYKKI 227
>At2g25090 [T] KOG0583 Serine/threonine protein kinase
Length = 469
Score = 95.5 bits (236), Expect = 2e-19
Identities = 82/296 (27%), Positives = 135/296 (44%), Gaps = 48/296 (16%)
Query: 215 DHVLTERDILTTTRSEWLVKLLYAFQDPQSLYLAMEFVPGGDFRTLLLNTKFLQAPHARF 274
+ + E ++ R +V+L + ++ ME+V GG+ ++ L AR
Sbjct: 59 EQIEREIAVMRLLRHPNVVELREVMATKKKIFFVMEYVNGGELFEMIDRDGKLPEDLARK 118
Query: 275 YISEMFCAVNALHQLGYTHRDLKPENFLIDSKGHIKLTDFGLASGTVSMERIESMKIRLQ 334
Y ++ AV+ H G HRD+KPEN L+D +G +K+TDFGL++
Sbjct: 119 YFQQLISAVDFCHSRGVFHRDIKPENLLLDGEGDLKVTDFGLSA---------------- 162
Query: 335 EVKNLEFPEFRERSMDDRRRMYNKLREEEVRYAHSTVGSPDYMALEVLEAKNYDFTV-DY 393
L PE + RR + L H+ G+P Y+A EVL K YD + D
Sbjct: 163 ----LMMPE----GLGGRRGSSDDL-------LHTRCGTPAYVAPEVLRNKGYDGAMADI 207
Query: 394 WSLGCILFESLVGYTPFSGNSTNETYENLRNWKHVLQRPKCDNGRYAFSDRTWELITR-L 452
WS G +L+ L G+ PF EN+ + + +C+ + FS + EL++R L
Sbjct: 208 WSCGIVLYALLAGFLPFID-------ENVMTLYTKIFKAECEFPPW-FSLESKELLSRLL 259
Query: 453 IADPINRLKSFEHVKRMRYFSE-----IDFNTLRTI-HPPFIPQLDNEEDVGYFDD 502
+ DP R+ S +K + +F + + F+ TI PP P ++D+ +D
Sbjct: 260 VPDPEQRI-SMSEIKMIPWFRKNFTPSVAFSIDETIPSPPEPPTKKKKKDLNEKED 314
>CE28740 [T] KOG0592 3-phosphoinositide-dependent protein kinase (PDK1)
Length = 636
Score = 95.1 bits (235), Expect = 2e-19
Identities = 77/288 (26%), Positives = 128/288 (43%), Gaps = 33/288 (11%)
Query: 215 DHVLTERDILTTTRSE-----WLVKLLYAFQDPQSLYLAMEFVPGGDFRTLLLNTKFLQA 269
D ++ E++ILT E ++ +L F D +Y + V GD L +
Sbjct: 112 DAIIREKNILTYLSQECGGHPFVTQLYTHFHDQARIYFVIGLVENGDLGESLCHFGSFDM 171
Query: 270 PHARFYISEMFCAVNALHQLGYTHRDLKPENFLIDSKGHIKLTDFGLASGTVSMERIESM 329
++F+ SE+ + LH HRD+KP+N LI GHI +TDFG A ++
Sbjct: 172 LTSKFFASEILTGLQFLHDNKIVHRDMKPDNVLIQKDGHILITDFGSAQAFGGLQ----- 226
Query: 330 KIRLQEVKNLEFPEFRERSMDD----RRRMYN--KLREEEVRYAHSTVGSPDYMALEVLE 383
L + + + RS D R Y+ ++ EE + VG+ Y++ E+L
Sbjct: 227 ---LSQEGFTDANQASSRSSDSGSPPPTRFYSDEEVPEENTARRTTFVGTALYVSPEMLA 283
Query: 384 AKNYDFTVDYWSLGCILFESLVGYTPFSGNSTNETYENLRNWKHVLQRPKCDNGRY--AF 441
+ D W LGCILF+ L G PF N H+L+R + + + F
Sbjct: 284 DGDVGPQTDIWGLGCILFQCLAGQPPF----------RAVNQYHLLKRIQELDFSFPEGF 333
Query: 442 SDRTWELITR-LIADPINRLKSFEHVKRMRYFSEIDFNTLRTIHPPFI 488
+ E+I + L+ DP R+ S + + ++F +D+ + I PP +
Sbjct: 334 PEEASEIIAKILVRDPSTRITS-QELMAHKFFENVDWVNIANIKPPVL 380
>CE22877 [D] KOG0575 Polo-like serine/threonine protein kinase
Length = 632
Score = 94.7 bits (234), Expect = 3e-19
Identities = 64/240 (26%), Positives = 101/240 (41%), Gaps = 41/240 (17%)
Query: 190 RKKDTKEICAXXXXXXXXXXXXEGTDHVLTERDILTTTRSEWLVKLLYAFQDPQSLYLAM 249
R K T E+ A D + E I + +VKL + F+D ++Y+ +
Sbjct: 54 RNKSTGELFAGKVVPKALLIKQYQRDKMAQEVQIHRNLQHRNVVKLYHFFEDKSNVYITL 113
Query: 250 EFVPGGDFRTLLLNTKFLQAPHARFYISEMFCAVNALHQLGYTHRDLKPENFLIDSKGHI 309
E P L K + P AR++ ++ V LH L HRDLK N ++ + +
Sbjct: 114 ELCPRRSLMELHKRRKAVTEPEARYFTYQIVEGVLYLHNLKIVHRDLKLGNLFLNDELQV 173
Query: 310 KLTDFGLASGTVSMERIESMKIRLQEVKNLEFPEFRERSMDDRRRMYNKLREEEVRYAHS 369
K+ DFGLA+ + ER +++
Sbjct: 174 KIGDFGLATTCDNDERKKTL---------------------------------------- 193
Query: 370 TVGSPDYMALEVLEAKNYDFTVDYWSLGCILFESLVGYTPFSGNSTNETYENLRNWKHVL 429
G+P+Y+A EVL + F VD W++GCIL+ L G+ PF S ETY ++N +V+
Sbjct: 194 -CGTPNYIAPEVLNKIGHSFEVDLWAIGCILYILLFGHPPFESKSLEETYSRIKNNNYVI 252
>At5g45820 [T] KOG0583 Serine/threonine protein kinase
Length = 439
Score = 94.7 bits (234), Expect = 3e-19
Identities = 77/281 (27%), Positives = 120/281 (42%), Gaps = 51/281 (18%)
Query: 215 DHVLTERDILTTTRSEWLVKLLYAFQDPQSLYLAMEFVPGGDFRTLLLNTKFLQAPHARF 274
D + E ++ R +V L +Y AME+V GG+ + K L+ AR
Sbjct: 55 DQIKREISVMRLVRHPHVVFLHEVMASKTKIYFAMEYVKGGELFDKVSKGK-LKENIARK 113
Query: 275 YISEMFCAVNALHQLGYTHRDLKPENFLIDSKGHIKLTDFGLASGTVSMERIESMKIRLQ 334
Y ++ A++ H G HRDLKPEN L+D G +K++DFGL++
Sbjct: 114 YFQQLIGAIDYCHSRGVYHRDLKPENLLLDENGDLKISDFGLSA---------------- 157
Query: 335 EVKNLEFPEFRERSMDDRRRMYNKLREEEVRYAHSTVGSPDYMALEVLEAKNYD-FTVDY 393
RE D H+T G+P Y+A EV+ K YD D
Sbjct: 158 ---------LRESKQQD-------------GLLHTTCGTPAYVAPEVIGKKGYDGAKADV 195
Query: 394 WSLGCILFESLVGYTPFSGNSTNETYENLRNWKHVLQRPKCDNGRYAFSDRTWELITRLI 453
WS G +L+ L G+ PF + E Y + + KC N F +L++R++
Sbjct: 196 WSCGVVLYVLLAGFLPFHEQNLVEMYRKITKGEF-----KCPNW---FPPEVKKLLSRIL 247
Query: 454 -ADPINRLKSFEHVKRMRYFSEIDFNTLRTIHPPFIPQLDN 493
+P +R+K E + +F + F + T P Q+D+
Sbjct: 248 DPNPNSRIK-IEKIMENSWFQK-GFKKIETPKSPESHQIDS 286
>At4g30960 [T] KOG0583 Serine/threonine protein kinase
Length = 441
Score = 94.7 bits (234), Expect = 3e-19
Identities = 81/295 (27%), Positives = 120/295 (40%), Gaps = 52/295 (17%)
Query: 215 DHVLTERDILTTTRSEWLVKLLYAFQDPQSLYLAMEFVPGGDFRTLLLNTKFLQAPHARF 274
D + E ++ + +V+L +Y AME V GG+ + + L+ AR
Sbjct: 67 DQIKREISVMRMVKHPNIVELHEVMASKSKIYFAMELVRGGELFAKVAKGR-LREDVARV 125
Query: 275 YISEMFCAVNALHQLGYTHRDLKPENFLIDSKGHIKLTDFGLASGTVSMERIESMKIRLQ 334
Y ++ AV+ H G HRDLKPEN L+D +G++K+TDFGL++
Sbjct: 126 YFQQLISAVDFCHSRGVYHRDLKPENLLLDEEGNLKVTDFGLSA---------------- 169
Query: 335 EVKNLEFPEFRERSMDDRRRMYNKLREEEVRYAHSTVGSPDYMALEVLEAKNYD-FTVDY 393
F E D H+T G+P Y+A EV+ K YD D
Sbjct: 170 ---------FTEHLKQD-------------GLLHTTCGTPAYVAPEVILKKGYDGAKADL 207
Query: 394 WSLGCILFESLVGYTPFSGNSTNETYENLRNWKHVLQRPKCDNGRYAFSDRTWELITRLI 453
WS G ILF L GY PF ++ Y + KC S L+T+L+
Sbjct: 208 WSCGVILFVLLAGYLPFQDDNLVNMYRKIYRGDF-----KCPGW---LSSDARRLVTKLL 259
Query: 454 ADPINRLKSFEHVKRMRYFSEIDFNTLRTIHPPFIPQL-DNEEDVGYFDDFTNEE 507
N + E V +F + R+ + P + EEDV + + EE
Sbjct: 260 DPNPNTRITIEKVMDSPWFKK---QATRSRNEPVAATITTTEEDVDFLVHKSKEE 311
>At4g24400 [T] KOG0583 Serine/threonine protein kinase
Length = 445
Score = 94.7 bits (234), Expect = 3e-19
Identities = 62/223 (27%), Positives = 96/223 (42%), Gaps = 41/223 (18%)
Query: 189 ARKKDTKEICAXXXXXXXXXXXXEGTDHVLTERDILTTTRSEWLVKLLYAFQDPQSLYLA 248
A+ +T E A + D + E I+ R +V+L +Y+
Sbjct: 26 AQNTETGESVAMKIVDRSTIIKRKMVDQIKREISIMKLVRHPCVVRLYEVLASRTKIYII 85
Query: 249 MEFVPGGDFRTLLLNTKFLQAPHARFYISEMFCAVNALHQLGYTHRDLKPENFLIDSKGH 308
+E++ GG+ ++ L AR Y ++ V+ H G HRDLKPEN L+DS+G+
Sbjct: 86 LEYITGGELFDKIVRNGRLSESEARKYFHQLIDGVDYCHSKGVYHRDLKPENLLLDSQGN 145
Query: 309 IKLTDFGLASGTVSMERIESMKIRLQEVKNLEFPEFRERSMDDRRRMYNKLREEEVRYAH 368
+K++DFGL++ L E+ V
Sbjct: 146 LKISDFGLSA----------------------------------------LPEQGVTILK 165
Query: 369 STVGSPDYMALEVLEAKNYDFTV-DYWSLGCILFESLVGYTPF 410
+T G+P+Y+A EVL K Y+ V D WS G IL+ + GY PF
Sbjct: 166 TTCGTPNYVAPEVLSHKGYNGAVADIWSCGVILYVLMAGYLPF 208
>At4g18700 [T] KOG0583 Serine/threonine protein kinase
Length = 489
Score = 94.7 bits (234), Expect = 3e-19
Identities = 77/274 (28%), Positives = 114/274 (41%), Gaps = 44/274 (16%)
Query: 153 LTKETNILRKRRLKPKHK---DFEMITXXXXXXXXXXXLARKKDTKEICAXXXXXXXXXX 209
+T+ET+ L K R P+ +EM LAR T E A
Sbjct: 5 ITRETS-LPKERSSPQALILGRYEMGKLLGHGTFAKVYLARNVKTNESVAIKVIDKEKVL 63
Query: 210 XXEGTDHVLTERDILTTTRSEWLVKLLYAFQDPQSLYLAMEFVPGGDFRTLLLNTKFLQA 269
H+ E IL R +V+L +Y ME+V GG+ + + L+
Sbjct: 64 KGGLIAHIKREISILRRVRHPNIVQLFEVMATKAKIYFVMEYVRGGELFNKVAKGR-LKE 122
Query: 270 PHARFYISEMFCAVNALHQLGYTHRDLKPENFLIDSKGHIKLTDFGLASGTVSMERIESM 329
AR Y ++ AV H G HRDLKPEN L+D G++K++DFGL++
Sbjct: 123 EVARKYFQQLISAVTFCHARGVYHRDLKPENLLLDENGNLKVSDFGLSA----------- 171
Query: 330 KIRLQEVKNLEFPEFRERSMDDRRRMYNKLREEEVRYAHSTVGSPDYMALEVLEAKNYDF 389
+ +++R++ + H+ G+P Y+A EVL K YD
Sbjct: 172 -------------------------VSDQIRQDGL--FHTFCGTPAYVAPEVLARKGYDA 204
Query: 390 T-VDYWSLGCILFESLVGYTPFSGNSTNETYENL 422
VD WS G ILF + GY PF + Y+ +
Sbjct: 205 AKVDIWSCGVILFVLMAGYLPFHDRNVMAMYKKI 238
>SPAC17G8.14c [T] KOG0694 Serine/threonine protein kinase
Length = 896
Score = 94.4 bits (233), Expect = 4e-19
Identities = 79/353 (22%), Positives = 142/353 (39%), Gaps = 61/353 (17%)
Query: 161 RKRRLKPKHKDFEMITXXXXXXXXXXXLARKKDTKEICAXXXXXXXXXXXXEGTDHVLTE 220
R+++ + DF + LA K K+ A E + + TE
Sbjct: 561 REKKNRVTLDDFTFLAVLGKGNFGKVMLAEYKVNKKFYAIKVLKKEAILKNEELESLKTE 620
Query: 221 RDILTTTRSE---WLVKLLYAFQDPQSLYLAMEFVPGGDFRTLLLNTKFLQAPHARFYIS 277
+ + E +L+ L +FQ +Y ME++ GGD + +F ARFY +
Sbjct: 621 KHVFEVANKEKHPFLLNLFASFQTSTRVYFVMEYILGGDLMVHIQRQQF-SVKRARFYGA 679
Query: 278 EMFCAVNALHQLGYTHRDLKPENFLIDSKGHIKLTDFGLASGTVSMERIESMKIRLQEVK 337
E+ A+ H+ G +RDLK +N L+ GHI++ D+GL + + S
Sbjct: 680 EVCLALKYFHENGIAYRDLKLDNILLCPDGHIRIADYGLCKENMLLGNTTS--------- 730
Query: 338 NLEFPEFRERSMDDRRRMYNKLREEEVRYAHSTVGSPDYMALEVLEAKNYDFTVDYWSLG 397
+ G+P++MA E+L + Y VD+W+ G
Sbjct: 731 -------------------------------TFCGTPEFMAPEILLEQQYSKDVDWWAFG 759
Query: 398 CILFESLVGYTPFSGNSTNETYENLRNWKHV--LQRPKCDNGRYAFSDRTWELITRLIAD 455
++++ L+G +PF G E ++ + + + + + P +D L L D
Sbjct: 760 VLMYQMLLGQSPFKGEDEEEIFDAILSDEPLFPINMP---------ADAVSLLRGLLTRD 810
Query: 456 PINRL----KSFEHVKRMRYFSEIDFNTL--RTIHPPFIPQLDNEEDVGYFDD 502
P RL K V +F+ I ++ L + P + P +++ D+ FD+
Sbjct: 811 PNQRLGSGPKDANEVMAHPFFASIVWDDLYNKLYEPSYKPLINDPRDLNNFDE 863
>Hs4885055 [T] KOG0986 G protein-coupled receptor kinase
Length = 688
Score = 94.0 bits (232), Expect = 6e-19
Identities = 84/330 (25%), Positives = 137/330 (41%), Gaps = 65/330 (19%)
Query: 190 RKKDTKEICAXXXXXXXXXXXXEGTDHVLTER---DILTTTRSEWLVKLLYAFQDPQSLY 246
RK DT ++ A +G L ER +++T ++V + YAF P L
Sbjct: 209 RKADTGKMYAMKCLDKKRIKMKQGETLALNERIMLSLVSTGDCPFIVCMTYAFHTPDKLC 268
Query: 247 LAMEFVPGGDFRTLLLNTKFLQAPHARFYISEMFCAVNALHQLGYTHRDLKPENFLIDSK 306
++ + GGD L RFY +E+ + +H +RDLKP N L+D
Sbjct: 269 FILDLMNGGDLHYHLSQHGVFSEKEMRFYATEIILGLEHVHNRFVVYRDLKPANILLDEH 328
Query: 307 GHIKLTDFGLASGTVSMERIESMKIRLQEVKNLEFPEFRERSMDDRRRMYNKLREEEVRY 366
GH +++D GLA +F ++
Sbjct: 329 GHARISDLGLAC------------------------DFSKKK------------------ 346
Query: 367 AHSTVGSPDYMALEVLE-AKNYDFTVDYWSLGCILFESLVGYTPFSGNSTNETYENLRNW 425
H++VG+ YMA EVL+ YD + D++SLGC+LF+ L G++PF + T + +E R
Sbjct: 347 PHASVGTHGYMAPEVLQKGTAYDSSADWFSLGCMLFKLLRGHSPFRQHKTKDKHEIDRMT 406
Query: 426 KHV-LQRPKCDNGRYAFSDRTWELITRLIADPINRL-----KSFEHVKRMRYFSEIDFN- 478
V ++ P FS L+ L+ +++ + VK +F +D+
Sbjct: 407 LTVNVELPD------TFSPELKSLLEGLLQRDVSKRLGCHGGGSQEVKEHSFFKGVDWQH 460
Query: 479 -TLRTIHPPFIP-----QLDNEEDVGYFDD 502
L+ PP IP + D+G FD+
Sbjct: 461 VYLQKYPPPLIPPRGEVNAADAFDIGSFDE 490
>At1g30270 [T] KOG0583 Serine/threonine protein kinase
Length = 480
Score = 94.0 bits (232), Expect = 6e-19
Identities = 55/192 (28%), Positives = 87/192 (44%), Gaps = 41/192 (21%)
Query: 232 LVKLLYAFQDPQSLYLAMEFVPGGDFRTLLLNTKFLQAPHARFYISEMFCAVNALHQLGY 291
++++ +Y +EFV GG+ + + L+ AR Y ++ AV+ H G
Sbjct: 91 VIRMFEVMASKTKIYFVLEFVTGGELFDKISSNGRLKEDEARKYFQQLINAVDYCHSRGV 150
Query: 292 THRDLKPENFLIDSKGHIKLTDFGLASGTVSMERIESMKIRLQEVKNLEFPEFRERSMDD 351
HRDLKPEN L+D+ G +K++DFGL++
Sbjct: 151 YHRDLKPENLLLDANGALKVSDFGLSA--------------------------------- 177
Query: 352 RRRMYNKLREEEVRYAHSTVGSPDYMALEVLEAKNYD-FTVDYWSLGCILFESLVGYTPF 410
L ++E H+T G+P+Y+A EV+ K YD D WS G ILF + GY PF
Sbjct: 178 -------LPQQEDGLLHTTCGTPNYVAPEVINNKGYDGAKADLWSCGVILFVLMAGYLPF 230
Query: 411 SGNSTNETYENL 422
++ Y+ +
Sbjct: 231 EDSNLTSLYKKI 242
>7301972 [T] KOG0616 cAMP-dependent protein kinase catalytic subunit (PKA)
Length = 393
Score = 94.0 bits (232), Expect = 6e-19
Identities = 57/224 (25%), Positives = 102/224 (45%), Gaps = 43/224 (19%)
Query: 188 LARKKDTKEICAXXXXXXXXXXXXEGTDHVLTERDILTTTRSEWLVKLLYAFQDPQSLYL 247
L R+K K A + HV E+ +L R +L+ L+ + + LYL
Sbjct: 61 LVREKSGKNYYAAKMMSKEDLVRLKQVAHVHNEKHVLNAARFPFLIYLVDSTKCFDYLYL 120
Query: 248 AMEFVPGGDFRTLLLNTKFLQAPHARFYISEMFCAVNALHQLGYTHRDLKPENFLIDSKG 307
+ V GG+ + + HARFY +++ A+ +H++ +RDLKPEN L+D +G
Sbjct: 121 ILPLVNGGELFSYHRRVRKFNEKHARFYAAQVALALEYMHKMHLMYRDLKPENILLDQRG 180
Query: 308 HIKLTDFGLASGTVSMERIESMKIRLQEVKNLEFPEFRERSMDDRRRMYNKLREEEVRYA 367
+IK+TDFG + +D R
Sbjct: 181 YIKITDFGFT-----------------------------KRVDGR--------------T 197
Query: 368 HSTVGSPDYMALEVLEAKNYDFTVDYWSLGCILFESLVGYTPFS 411
+ G+P+Y+A E+++ + Y+ +VD+W+ G +++E + G +PF+
Sbjct: 198 STLCGTPEYLAPEIVQLRPYNKSVDWWAFGILVYEFVAGRSPFA 241
>CE07285 [D] KOG0575 Polo-like serine/threonine protein kinase
Length = 615
Score = 93.6 bits (231), Expect = 7e-19
Identities = 74/270 (27%), Positives = 112/270 (41%), Gaps = 55/270 (20%)
Query: 232 LVKLLYAFQDPQSLYLAMEFVPGGDFRTLLLNTKFLQAPHARFYISEMFCAVNALHQLGY 291
+V+ + F+D Q++Y +E L L ARFY ++ V LH L
Sbjct: 95 IVQFHHFFEDSQNVYFTLELCSKNSLMELNKQRGPLTEHEARFYTIQVAEGVKHLHNLQI 154
Query: 292 THRDLKPENFLIDSKGHIKLTDFGLASGTVSMERIESMKIRLQEVKNLEFPEFRERSMDD 351
HRDLK N ++ +K+ DFGLA+ F E E+ M
Sbjct: 155 IHRDLKLGNLFLNEHLQVKIGDFGLAT----------------------FCEKNEKKM-- 190
Query: 352 RRRMYNKLREEEVRYAHSTVGSPDYMALEVLEAKNYDFTVDYWSLGCILFESLVGYTPFS 411
+ G+P+Y+A EVL + F VD W++GCIL+ L G PF
Sbjct: 191 -----------------TRGGTPNYIAPEVLNETGHAFEVDIWAIGCILYVLLFGSPPFE 233
Query: 412 GNSTNETYENLRNWKHVLQRPKCDNGRYAFSDRTWELITRLIADPI-NRLKSFEHVKRMR 470
ETY ++N +V+ + T + R + DP+ +R + E V +
Sbjct: 234 SRRVQETYVRIKNNDYVVPEN---------ASPTANRLIRSLLDPVPDRRPTAEAVLLDQ 284
Query: 471 YFSEIDFNTLRTIHPPFIPQLDNEEDVGYF 500
+F T+ +PP QL E+DV YF
Sbjct: 285 FFK----TTIEPTYPPVHQQLHKEQDVKYF 310
>At2g34180 [T] KOG0583 Serine/threonine protein kinase
Length = 502
Score = 92.4 bits (228), Expect = 2e-18
Identities = 75/266 (28%), Positives = 114/266 (42%), Gaps = 61/266 (22%)
Query: 216 HVLTERDILTTTRSEWLVKLLYAFQDPQSLYLAMEFVPGGDFRTLLLNTKFLQAPHARFY 275
H+ E IL R ++V LL +Y+ ME+V GG+ + + L+ AR Y
Sbjct: 101 HIKREISILRRVRHPYIVHLLEVMATKTKIYIVMEYVRGGELYNTVARGR-LREGTARRY 159
Query: 276 ISEMFCAVNALHQLGYTHRDLKPENFLIDSKGHIKLTDFGLASGTVSMERIESMKIRLQE 335
++ +V H G HRDLK EN L+D KG++K++DFGL+
Sbjct: 160 FQQLISSVAFCHSRGVYHRDLKLENLLLDDKGNVKVSDFGLSV----------------- 202
Query: 336 VKNLEFPEFRERSMDDRRRMYNKLREEEVRYAHSTVGSPDYMALEVLEAKNYD-FTVDYW 394
+ +L++E + + G+P Y+A EVL K Y+ D W
Sbjct: 203 -------------------VSEQLKQEGI--CQTFCGTPAYLAPEVLTRKGYEGAKADIW 241
Query: 395 SLGCILFESLVGYTPFSGNSTNETYENLRNWKHVLQRPKCDNGRYAFSDRTWELITRLI- 453
S G ILF + GY PF + Y + +K + PK FS L+TR++
Sbjct: 242 SCGVILFVLMAGYLPFDDKNILVMYTKI--YKGQFKCPKW------FSPELARLVTRMLD 293
Query: 454 ADPINRL------------KSFEHVK 467
+P R+ K F+HVK
Sbjct: 294 TNPDTRITIPEIMKHRWFKKGFKHVK 319
>SPCC1450.11c [R] KOG0605 NDR and related serine/threonine kinases
Length = 1338
Score = 91.7 bits (226), Expect = 3e-18
Identities = 61/184 (33%), Positives = 87/184 (47%), Gaps = 9/184 (4%)
Query: 167 PKHKDFEMITXXXXXXXXXXXLARKKDTKEICAXXXXXXXXXXXXEGTDHVLTERDILTT 226
P D++++ LA+K+ T + A +V ER IL +
Sbjct: 584 PSINDYKILKPISKGAFGSVYLAQKRTTGDYFAIKILKKSNMIAKNQVINVRAERAILMS 643
Query: 227 T-RSEWLVKLLYAFQDPQSLYLAMEFVPGGDFRTLLLNTKFLQAPHARFYISEMFCAVNA 285
S ++ KL Y FQ LYL ME++ GGD +LL L R YI+E +
Sbjct: 644 QGESPFVAKLYYTFQSKDYLYLVMEYLNGGDCGSLLKTMGVLDLDWIRTYIAETVLCLGD 703
Query: 286 LHQLGYTHRDLKPENFLIDSKGHIKLTDFGLASGTVSMERIESMK-IRLQEVKNLEFPEF 344
LH G HRD+KPEN LI GH+KLTDFGL+ R+ MK R ++ ++ +
Sbjct: 704 LHDRGIIHRDIKPENLLISQNGHLKLTDFGLS-------RVGYMKRHRRKQSSSIPVLDL 756
Query: 345 RERS 348
R+RS
Sbjct: 757 RDRS 760
Score = 78.2 bits (191), Expect = 3e-14
Identities = 46/138 (33%), Positives = 74/138 (53%), Gaps = 15/138 (10%)
Query: 371 VGSPDYMALEVLEAKNYDFTVDYWSLGCILFESLVGYTPFSGNSTNETYENLR----NWK 426
+G+PDY+A EV+ D+WSLGC++FE L GY PF+ + ++ ++N+ NW
Sbjct: 858 IGTPDYIAPEVILGNPGIKASDWWSLGCVVFEFLFGYPPFNAETPDQVFQNILARRINWP 917
Query: 427 HVLQRPKCDNGRYAFSDRTWELITRLIA-DPINRL--KSFEHVKRMRYFSEIDFNTLRTI 483
+ A S +LI RL+ +P NRL E +K +F ++++T+
Sbjct: 918 AEVFT--------AESSVALDLIDRLLCMNPANRLGANGVEEIKAHPFFKSVNWDTILEE 969
Query: 484 HPPFIPQLDNEEDVGYFD 501
PPF+P+ + ED YFD
Sbjct: 970 DPPFVPKPFSPEDTVYFD 987
>At5g45810 [T] KOG0583 Serine/threonine protein kinase
Length = 483
Score = 91.7 bits (226), Expect = 3e-18
Identities = 61/208 (29%), Positives = 95/208 (45%), Gaps = 40/208 (19%)
Query: 216 HVLTERDILTTTRSEWLVKLLYAFQDPQSLYLAMEFVPGGDFRTLLLNTKFLQAPHARFY 275
H+ E IL R +V+L +Y ME+V GG+ + + L+ AR Y
Sbjct: 72 HIKREISILRRVRHPNIVQLFEVMATKSKIYFVMEYVKGGELFNKVAKGR-LKEEMARKY 130
Query: 276 ISEMFCAVNALHQLGYTHRDLKPENFLIDSKGHIKLTDFGLASGTVSMERIESMKIRLQE 335
++ AV+ H G HRDLKPEN L+D G++K++DFGL++
Sbjct: 131 FQQLISAVSFCHFRGVYHRDLKPENLLLDENGNLKVSDFGLSA----------------- 173
Query: 336 VKNLEFPEFRERSMDDRRRMYNKLREEEVRYAHSTVGSPDYMALEVLEAKNYD-FTVDYW 394
+ +++R++ + H+ G+P Y+A EVL K YD VD W
Sbjct: 174 -------------------VSDQIRQDGL--FHTFCGTPAYVAPEVLARKGYDGAKVDIW 212
Query: 395 SLGCILFESLVGYTPFSGNSTNETYENL 422
S G ILF + G+ PF + Y+ +
Sbjct: 213 SCGVILFVLMAGFLPFHDRNVMAMYKKI 240
>At5g25110 [T] KOG0583 Serine/threonine protein kinase
Length = 460
Score = 91.7 bits (226), Expect = 3e-18
Identities = 70/259 (27%), Positives = 112/259 (43%), Gaps = 48/259 (18%)
Query: 215 DHVLTERDILTTTRSEWLVKLLYAFQDPQSLYLAMEFVPGGDFRTLLLNTKFLQAPHARF 274
+ + E I+ R +V+L ++ ME+V GG+ + ++ K L+ AR
Sbjct: 58 EQIKREISIMRLVRHPNIVELKEVMATKTKIFFIMEYVKGGELFSKIVKGK-LKEDSARK 116
Query: 275 YISEMFCAVNALHQLGYTHRDLKPENFLIDSKGHIKLTDFGLASGTVSMERIESMKIRLQ 334
Y ++ AV+ H G +HRDLKPEN L+D G +K++DFGL++
Sbjct: 117 YFQQLISAVDFCHSRGVSHRDLKPENLLVDENGDLKVSDFGLSA---------------- 160
Query: 335 EVKNLEFPEFRERSMDDRRRMYNKLREEEVRYAHSTVGSPDYMALEVLEAKNYDFTV-DY 393
E+ + D H+ G+P Y+A EVL K YD D
Sbjct: 161 ---------LPEQILQD-------------GLLHTQCGTPAYVAPEVLRKKGYDGAKGDI 198
Query: 394 WSLGCILFESLVGYTPFSGNSTNETYENLRNWKHVLQRPKCDNGRYAFSDRTWELITRLI 453
WS G IL+ L G+ PF + + Y + +K + P FS + LI++L+
Sbjct: 199 WSCGIILYVLLAGFLPFQDENLMKMYRKI--FKSEFEYPPW------FSPESKRLISKLL 250
Query: 454 ADPINRLKSFEHVKRMRYF 472
N+ S + R +F
Sbjct: 251 VVDPNKRISIPAIMRTPWF 269
>Hs14776113 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 424
Score = 91.3 bits (225), Expect = 4e-18
Identities = 73/262 (27%), Positives = 112/262 (41%), Gaps = 56/262 (21%)
Query: 212 EGTDHVLTERDILTTTRSEWLVKLLYAFQDPQSLYLAMEFVPGGD-FRTLLLNTKFLQAP 270
EG + +E +L R +++L+ F+ + +Y+ ME GG+ F ++ F +
Sbjct: 135 EGREVCESELRVLRRVRHANIIQLVEVFETQERVYMVMELATGGELFDRIIAKGSFTERD 194
Query: 271 HARFYISEMFCAVNALHQLGYTHRDLKPENFLIDSKG---HIKLTDFGLASGTVSMERIE 327
R + + V LH LG THRDLKPEN L G I +TDFGLAS
Sbjct: 195 ATRV-LQMVLDGVRYLHALGITHRDLKPENLLYYHPGTDSKIIITDFGLASA-------- 245
Query: 328 SMKIRLQEVKNLEFPEFRERSMDDRRRMYNKLREEEVRYAHSTVGSPDYMALEVLEAKNY 387
R++ D + +T G+P+Y+A EVL K Y
Sbjct: 246 -----------------RKKGDDCLMK--------------TTCGTPEYIAPEVLVRKPY 274
Query: 388 DFTVDYWSLGCILFESLVGYTPFSGNSTNETYENLRNWKHVLQRPKCDNGRYAFSDRTWE 447
+VD W+LG I + L G PF ++ Y + G+Y++S W
Sbjct: 275 TNSVDMWALGVIAYILLSGTMPFEDDNRTRLYRQIL------------RGKYSYSGEPWP 322
Query: 448 LITRLIADPINRLKSFEHVKRM 469
++ L D I+RL + + RM
Sbjct: 323 SVSNLAKDFIDRLLTVDPGARM 344
>SPCC576.15c [T] KOG0592 3-phosphoinositide-dependent protein kinase (PDK1)
Length = 592
Score = 90.5 bits (223), Expect = 6e-18
Identities = 70/256 (27%), Positives = 114/256 (44%), Gaps = 37/256 (14%)
Query: 233 VKLLYAFQDPQSLYLAMEFVPGGDFRTLLLNTKFLQAPHARFYISEMFCAVNALHQLGYT 292
+KL Y FQD +LY + G+ + A++Y + + +++ +H G
Sbjct: 161 IKLFYTFQDAHNLYFVLSLARNGELLDYINKLGRFNEICAQYYAALIVDSIDYMHGRGVI 220
Query: 293 HRDLKPENFLIDSKGHIKLTDFGLASGTVSMERIESMKIRLQEVKNLEFPEFRERSMDDR 352
HRDLKPEN L+D K+TDFG A S S ++ + + P+ RS
Sbjct: 221 HRDLKPENILLDDNMRTKITDFGSAKILNS-----SHGSHEEDTHHADKPQAHSRSF--- 272
Query: 353 RRMYNKLREEEVRYAHSTVGSPDYMALEVLEAKNYDFTVDYWSLGCILFESLVGYTPFSG 412
VG+ Y++ EVL K D W+ GCILF+ L G PF
Sbjct: 273 ------------------VGTARYVSPEVLSDKIAGTASDIWAFGCILFQMLAGKPPFVA 314
Query: 413 NSTNETYENLRNWKHVLQRPKCDNGRYAFSDRTWELITR-LIADPINRLKSFEHVKRMRY 471
+ T++++ + + + SD +LI + L+ DP +RL + + + + +
Sbjct: 315 GNEYLTFQSILHLSYEIPPD--------ISDVASDLIKKLLVLDPKDRL-TVDEIHQHPF 365
Query: 472 FSEIDF-NTLRTIHPP 486
F+ I F NTL + PP
Sbjct: 366 FNGIKFDNTLWELPPP 381
>SPCC18B5.11c [D] KOG0615 Serine/threonine protein kinase Chk2 and related
proteins
Length = 460
Score = 90.5 bits (223), Expect = 6e-18
Identities = 68/267 (25%), Positives = 118/267 (43%), Gaps = 51/267 (19%)
Query: 214 TDHVLTERDILTTTRSEWLVKLLYAFQDPQSLYLAMEFVPGGDFRTLLLNTKFLQAPHAR 273
T+ E DIL + +V+ F++ L++ ME+V GGD L+ + +
Sbjct: 213 TEMFQREIDILKSLHHPGVVQCHEIFENDDELFIVMEYVEGGDLMDFLIANGSIDEQDCK 272
Query: 274 FYISEMFCAVNALHQLGYTHRDLKPENFLIDSKGHIKLTDFGLASGTVSMERIESMKIRL 333
+ ++ + LH+ G THRD+KPEN LI + H+K++DFGLA
Sbjct: 273 PLLKQLLETLLHLHKQGVTHRDIKPENILITNDFHLKISDFGLA---------------- 316
Query: 334 QEVKNLEFPEFRERSMDDRRRMYNKLREEEVRYAHSTVGSPDYMALEVLEAKN------Y 387
K+ + + G+ Y+A EVL++KN Y
Sbjct: 317 ------------------------KVIHGTGTFLETFCGTMGYLAPEVLKSKNVNLDGGY 352
Query: 388 DFTVDYWSLGCILFESLVGYTPFSGNSTNETYENLRNWKHVLQRPKCDNGRYAFSDRTWE 447
D VD WSLGC+L+ L PF+ +S + E + + ++ P +N S+ +
Sbjct: 353 DDKVDIWSLGCVLYVMLTASIPFASSSQAKCIELISKGAYPIE-PLLEN---EISEEGID 408
Query: 448 LITRLI-ADPINRLKSFEHVKRMRYFS 473
LI R++ +P R+ E ++ +++
Sbjct: 409 LINRMLEINPEKRISESEALQHPWFYT 435
>At2g45490 [D] KOG0580 Serine/threonine protein kinase
Length = 288
Score = 90.1 bits (222), Expect = 8e-18
Identities = 76/291 (26%), Positives = 123/291 (42%), Gaps = 50/291 (17%)
Query: 171 DFEMITXXXXXXXXXXXLARKKDTKEICAXXXXXXXXXXXXEGTDHVLTERDILTTTRSE 230
DFE+ LAR+ +K I A + + E +I T+ R
Sbjct: 21 DFEIGRPLGKGKFGRVYLAREAKSKYIVALKVIFKEQIEKYKIHHQLRREMEIQTSLRHP 80
Query: 231 WLVKLLYAFQDPQSLYLAMEFVPGGDFRTLLLNTKFLQAPHARFYISEMFCAVNALHQLG 290
+++L F D + ++L +E+ GG+ +L L A YI+ + A+ H
Sbjct: 81 NILRLFGWFHDNERIFLILEYAHGGELYGVLKQNGHLTEQQAATYIASLSQALAYCHGKC 140
Query: 291 YTHRDLKPENFLIDSKGHIKLTDFGLASGTVSMERIESMKIRLQEVKNLEFPEFRERSMD 350
HRD+KPEN L+D +G +K+ DFG + +S +
Sbjct: 141 VIHRDIKPENLLLDHEGRLKIADFG----------------------------WSVQSSN 172
Query: 351 DRRRMYNKLREEEVRYAHSTVGSPDYMALEVLEAKNYDFTVDYWSLGCILFESLVGYTPF 410
R+ M G+ DY+A E++E +++D+ VD W+LG + +E L G PF
Sbjct: 173 KRKTM---------------CGTLDYLAPEMVENRDHDYAVDNWTLGILCYEFLYGNPPF 217
Query: 411 SGNSTNETYENLRNWKHVLQRPKCDNGRYAFSDRTWELITR-LIADPINRL 460
S +T++ R K L P N S+ LI++ L+ DP RL
Sbjct: 218 EAESQKDTFK--RILKIDLSFPLTPN----VSEEAKNLISQLLVKDPSKRL 262
>At2g30360 [T] KOG0583 Serine/threonine protein kinase
Length = 435
Score = 89.7 bits (221), Expect = 1e-17
Identities = 85/343 (24%), Positives = 138/343 (39%), Gaps = 68/343 (19%)
Query: 232 LVKLLYAFQDPQSLYLAMEFVPGGDFRTLLLNTKFLQAPHARFYISEMFCAVNALHQLGY 291
+VKL ++ AMEFV GG+ + L +R Y ++ AV H G
Sbjct: 82 IVKLHEVMATKSKIFFAMEFVKGGELFNKISKHGRLSEDLSRRYFQQLISAVGYCHARGV 141
Query: 292 THRDLKPENFLIDSKGHIKLTDFGLASGTVSMERIESMKIRLQEVKNLEFPEFRERSMDD 351
HRDLKPEN LID G++K++DFGL++ T
Sbjct: 142 YHRDLKPENLLIDENGNLKVSDFGLSALT------------------------------- 170
Query: 352 RRRMYNKLREEEVRYAHSTVGSPDYMALEVLEAKNYD-FTVDYWSLGCILFESLVGYTPF 410
+++R + + H+ G+P Y+A E+L K Y+ VD WS G +LF + GY PF
Sbjct: 171 -----DQIRPDGL--LHTLCGTPAYVAPEILSKKGYEGAKVDVWSCGIVLFVLVAGYLPF 223
Query: 411 SGNSTNETYENLRNWKHVLQR-PKCDNGRYA-----FSDRTWELITRLIADP------IN 458
+ + Y+ + ++ R D R+ + T I ++ DP
Sbjct: 224 NDPNVMNMYKKIYKGEYRFPRWMSPDLKRFVSRLLDINPETRITIDEILKDPWFVRGGFK 283
Query: 459 RLK-------------SFEHVKRMRYFSEIDFNTLRTIHPPFIPQLDNEEDVGYFDDFTN 505
++K S E VK + F I +++ + F ++ + F +
Sbjct: 284 QIKFHDDEIEDQKVESSLEAVKSLNAFDLISYSSGLDLSGLFAGCSNSSGESERFLSEKS 343
Query: 506 EEHMARYVDVFKRQDRLTAMVDDSLSDSKLVGFTFRHRNGKDG 548
E +A V+ F R++ L + GF +NGK G
Sbjct: 344 PEMLAEEVEGFAREENLRM----KKKKEEEYGFEMEGQNGKFG 382
>YPL153c [D] KOG0615 Serine/threonine protein kinase Chk2 and related
proteins
Length = 821
Score = 89.4 bits (220), Expect = 1e-17
Identities = 90/353 (25%), Positives = 145/353 (40%), Gaps = 42/353 (11%)
Query: 112 DMFDYVISRRERTRQVINYLEEQR-RSNLMGTEQITNEWQGYLTKETNILRKRRLKPKHK 170
D+ VI ++ +Q + + R RSNL T +I + T + + K + K
Sbjct: 139 DILSLVIFINDKFKQCLEQNKVDRIRSNLKNTSKIASPGLTSSTASSMVANKTGI---FK 195
Query: 171 DFEMITXXXXXXXXXXXL-ARKKDTKEICAXXXXXXXXXXXXEGTDHVLTERDILTTTRS 229
DF +I A ++ T + A D V E ++L
Sbjct: 196 DFSIIDEVVGQGAFATVKKAIERTTGKTFAVKIISKRKVIG--NMDGVTRELEVLQKLNH 253
Query: 230 EWLVKLLYAFQDPQSLYLAMEFVPGGDFRTLLLNTKFLQAPHARFYISEMFCAVNALHQL 289
+V+L ++D +S Y+ MEFV GGD + + R ++ A+ +H +
Sbjct: 254 PRIVRLKGFYEDTESYYMVMEFVSGGDLMDFVAAHGAVGEDAGREISRQILTAIKYIHSM 313
Query: 290 GYTHRDLKPENFLI--DSKGHIKLTDFGLASGTVSMERIESMKIRLQEVKNLEFPEFRER 347
G +HRDLKP+N LI D +K+TDFGLA + +++ L V
Sbjct: 314 GISHRDLKPDNILIEQDDPVLVKITDFGLAKVQGNGSFMKTFCGTLAYV----------- 362
Query: 348 SMDDRRRMYNKLREEEVRYAHSTVGSPDYMALEVLEAKNYDFTVDYWSLGCILFESLVGY 407
EV T SPD E E Y VD WS+GC+++ L G+
Sbjct: 363 -------------APEVIRGKDTSVSPD----EYEERNEYSSLVDMWSMGCLVYVILTGH 405
Query: 408 TPFSGNSTNETYENLRNWKHVLQRPKCDNGRYAFSDRTWELITRLI-ADPINR 459
PFSG++ ++ Y+ + + + P D + S+ + I L+ DP NR
Sbjct: 406 LPFSGSTQDQLYKQIGRGSY-HEGPLKD---FRISEEARDFIDSLLQVDPNNR 454
>Hs6005850 [D] KOG0615 Serine/threonine protein kinase Chk2 and related
proteins
Length = 543
Score = 89.4 bits (220), Expect = 1e-17
Identities = 80/299 (26%), Positives = 123/299 (40%), Gaps = 70/299 (23%)
Query: 216 HVLTERDILTTTRSEWLVKLLYAFQDPQSLYLAMEFVPGGDFRTLLLNTKFLQAPHARFY 275
+V TE +IL ++K+ F D + Y+ +E + GG+ ++ K L+ + Y
Sbjct: 269 NVETEIEILKKLNHPCIIKIKNFF-DAEDYYIVLELMEGGELFDKVVGNKRLKEATCKLY 327
Query: 276 ISEMFCAVNALHQLGYTHRDLKPENFLIDSKGH---IKLTDFGLASGTVSMERIESMKIR 332
+M AV LH+ G HRDLKPEN L+ S+ IK+TDFG
Sbjct: 328 FYQMLLAVQYLHENGIIHRDLKPENVLLSSQEEDCLIKITDFG----------------- 370
Query: 333 LQEVKNLEFPEFRERSMDDRRRMYNKLREEEVRYAHSTVGSPDYMALEVLEA---KNYDF 389
++K+ E + G+P Y+A EVL + Y+
Sbjct: 371 -----------------------HSKIL-GETSLMRTLCGTPTYLAPEVLVSVGTAGYNR 406
Query: 390 TVDYWSLGCILFESLVGYTPFSGNSTNETYENLRNWKHVLQRPKCDNGRYAFSDRTWELI 449
VD WSLG ILF L GY PFS + T V + + +G+Y F W +
Sbjct: 407 AVDCWSLGVILFICLSGYPPFSEHRT-----------QVSLKDQITSGKYNFIPEVWAEV 455
Query: 450 TRLIADPINRLKSFEHVKRMRYFSEIDFNTLRTIHPPFIPQLDNEEDVGYFDDFTNEEH 508
+ D + +L + R F T + P+ L +E+ F D +EE+
Sbjct: 456 SEKALDLVKKLLVVDPKAR--------FTTEEALRHPW---LQDEDMKRKFQDLLSEEN 503
>CE20142 [T] KOG0592 3-phosphoinositide-dependent protein kinase (PDK1)
Length = 320
Score = 89.0 bits (219), Expect = 2e-17
Identities = 67/261 (25%), Positives = 112/261 (42%), Gaps = 40/261 (15%)
Query: 232 LVKLLYAFQDPQSLYLAMEFVPGGDFRTLLL---NTKFLQAPHARFYISEMFCAVNALHQ 288
+V L FQD +SLY +E+ GD TL+ ++KF A +R+Y + + A+ +H+
Sbjct: 95 IVTLYATFQDSESLYFVLEYAKYGDLCTLMQKQPDSKFNVAD-SRYYAANLLSALEHIHK 153
Query: 289 LGYTHRDLKPENFLIDSKGHIKLTDFGLASGTVSMERIESMKIRLQEVKNLEFPEFRERS 348
LG HRD+K +N L+ S G I LTDFG + ++I+
Sbjct: 154 LGIIHRDVKADNLLVKSDGRIMLTDFGSSKFLSDYQKIQE-------------------- 193
Query: 349 MDDRRRMYNKLREEEVRYAHST-VGSPDYMALEVLEAKNYDFTVDYWSLGCILFESLVGY 407
N + EE+ S+ VG+ ++ E+L + D W+ L+ L G
Sbjct: 194 --------NPVEEEQPTGRRSSFVGTAFFVTPELLTGSEMSPSSDLWAFSVTLYLFLTGI 245
Query: 408 TPFSGNSTNETYENLRNWKHVLQRPKCDNGRYAFSDRTWELITRLIADPINRLKSFEHVK 467
PF+ S + +++ + D + LI RL+ + + +K
Sbjct: 246 YPFNDMSEYLVFRRIQDILYTFSEDFPD-------ENAKNLIERLLVKEQKSRLTSQEIK 298
Query: 468 RMRYFSEIDFNTLRTIHPPFI 488
++F IDF L + PP I
Sbjct: 299 EHKFFESIDFEHLEQLEPPRI 319
>CE01554 [T] KOG0986 G protein-coupled receptor kinase
Length = 642
Score = 89.0 bits (219), Expect = 2e-17
Identities = 56/195 (28%), Positives = 90/195 (45%), Gaps = 43/195 (22%)
Query: 218 LTERDILTTTRSEWLVKLLYAFQDPQSLYLAMEFVPGGDFRTLLLNTK--FLQAPHARFY 275
L E+ IL S ++V L YA++ +L L + + GGD + L N +FY
Sbjct: 249 LNEKQILQRINSPFVVSLAYAYETKDALCLVLTLMNGGDLKFHLYNLMPGGFDEKRVQFY 308
Query: 276 ISEMFCAVNALHQLGYTHRDLKPENFLIDSKGHIKLTDFGLASGTVSMERIESMKIRLQE 335
+E+ + LH +RDLKPEN L+D GH++++D GLA V ++ E +K R
Sbjct: 309 AAEITLGLQHLHSERILYRDLKPENILLDDFGHVRISDLGLA---VEIKDNEPIKGR--- 362
Query: 336 VKNLEFPEFRERSMDDRRRMYNKLREEEVRYAHSTVGSPDYMALEVLEAKNYDFTVDYWS 395
VG+ YMA E+++ + Y + VD+W
Sbjct: 363 -----------------------------------VGTVGYMAPEIVKNERYSYGVDWWG 387
Query: 396 LGCILFESLVGYTPF 410
+GC+++E + G PF
Sbjct: 388 VGCLIYEMIEGKAPF 402
>At1g49180_1 [OUT] KOG0595 Serine/threonine-protein kinase involved in autophagy
Length = 225
Score = 89.0 bits (219), Expect = 2e-17
Identities = 58/213 (27%), Positives = 96/213 (44%), Gaps = 44/213 (20%)
Query: 215 DHVLTERDILTTTRSEWLVKLLYAFQDPQSLYLAMEFVPGGDFRTLLLNTKFLQAPHARF 274
D + E + L++ +++LL+ QD L + +E+ GG + + ++ A+
Sbjct: 47 DCLNNELEFLSSVDHPNIIRLLHVSQDDDFLVMVLEYCDGGTLSSYIQRYGRVEEDIAKR 106
Query: 275 YISEMFCAVNALHQLGYTHRDLKPENFLIDSKGH---IKLTDFGLASGTVSMERIESMKI 331
++ ++ + +H HRDLKPEN LID G +K+ DF LA
Sbjct: 107 FMKQIGAGLEIIHDNHIIHRDLKPENILIDGSGDDLVLKIADFSLA-------------- 152
Query: 332 RLQEVKNLEFPEFRERSMDDRRRMYNKLREEEVRYAHSTVGSPDYMALEVLEAKNYDFTV 391
R+++ +Y + GSP YMA EVL+ + Y+
Sbjct: 153 ---------------------RKLHPG------KYLETVCGSPFYMAPEVLQFQRYNEKA 185
Query: 392 DYWSLGCILFESLVGYTPFSGNSTNETYENLRN 424
D WS+G ILFE L GY PF GN+ + N+++
Sbjct: 186 DMWSVGAILFELLHGYPPFRGNNNVQVLRNIKS 218
>Hs9966875 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 357
Score = 88.2 bits (217), Expect = 3e-17
Identities = 77/310 (24%), Positives = 120/310 (37%), Gaps = 50/310 (16%)
Query: 162 KRRLKPKHKDFEMITXXXXXXXXXXXLARKKDTKEICAXXXXXXXXXXXXEGTDHVLTER 221
K++ + K FE LA +K T ++ A E + + E
Sbjct: 13 KKQAEDIKKIFEFKETLGTGAFSEVVLAEEKATGKLFAVKCIPKKALKGKESS--IENEI 70
Query: 222 DILTTTRSEWLVKLLYAFQDPQSLYLAMEFVPGGDFRTLLLNTKFLQAPHARFYISEMFC 281
+L + E +V L ++ P LYL M+ V GG+ ++ F A I ++
Sbjct: 71 AVLRKIKHENIVALEDIYESPNHLYLVMQLVSGGELFDRIVEKGFYTEKDASTLIRQVLD 130
Query: 282 AVNALHQLGYTHRDLKPENFLI---DSKGHIKLTDFGLASGTVSMERIESMKIRLQEVKN 338
AV LH++G HRDLKPEN L D + I ++DFGL+
Sbjct: 131 AVYYLHRMGIVHRDLKPENLLYYSQDEESKIMISDFGLSK-------------------- 170
Query: 339 LEFPEFRERSMDDRRRMYNKLREEEVRYAHSTVGSPDYMALEVLEAKNYDFTVDYWSLGC 398
E + + G+P Y+A EVL K Y VD WS+G
Sbjct: 171 ---------------------MEGKGDVMSTACGTPGYVAPEVLAQKPYSKAVDCWSIGV 209
Query: 399 ILFESLVGYTPFSGNSTNETYENLRNWKHVLQRPKCDNGRYAFSDRTWELITRLIADPIN 458
I + L GY PF + ++ +E + ++ P D+ SD + I L+ N
Sbjct: 210 IAYILLCGYPPFYDENDSKLFEQILKAEYEFDSPYWDD----ISDSAKDFIRNLMEKDPN 265
Query: 459 RLKSFEHVKR 468
+ + E R
Sbjct: 266 KRYTCEQAAR 275
>Hs4507275 [D] KOG0580 Serine/threonine protein kinase
Length = 403
Score = 88.2 bits (217), Expect = 3e-17
Identities = 72/255 (28%), Positives = 109/255 (42%), Gaps = 46/255 (18%)
Query: 170 KDFEMITXXXXXXXXXXXLARKKDTKEICAXXXXXXXXXXXXEGTDHVLT-ERDILTTTR 228
+DFE+ LAR+K +K I A G +H L E +I + R
Sbjct: 131 EDFEIGRPLGKGKFGNVYLAREKQSKFILALKVLFKAQLEKA-GVEHQLRREVEIQSHLR 189
Query: 229 SEWLVKLLYAFQDPQSLYLAMEFVPGGD-FRTLLLNTKFLQAPHARFYISEMFCAVNALH 287
+++L F D +YL +E+ P G +R L +KF + A YI+E+ A++ H
Sbjct: 190 HPNILRLYGYFHDATRVYLILEYAPLGTVYRELQKLSKFDEQRTAT-YITELANALSYCH 248
Query: 288 QLGYTHRDLKPENFLIDSKGHIKLTDFGLASGTVSMERIESMKIRLQEVKNLEFPEFRER 347
HRD+KPEN L+ S G +K+ DFG + S R
Sbjct: 249 SKRVIHRDIKPENLLLGSAGELKIADFGWSVHAPSSRRT--------------------- 287
Query: 348 SMDDRRRMYNKLREEEVRYAHSTVGSPDYMALEVLEAKNYDFTVDYWSLGCILFESLVGY 407
+ G+ DY+ E++E + +D VD WSLG + +E LVG
Sbjct: 288 ---------------------TLCGTLDYLPPEMIEGRMHDEKVDLWSLGVLCYEFLVGK 326
Query: 408 TPFSGNSTNETYENL 422
PF N+ ETY+ +
Sbjct: 327 PPFEANTYQETYKRI 341
>CE03584 [T] KOG0607 MAP kinase-interacting kinase and related
serine/threonine protein kinases
Length = 761
Score = 88.2 bits (217), Expect = 3e-17
Identities = 76/270 (28%), Positives = 110/270 (40%), Gaps = 50/270 (18%)
Query: 217 VLTERDILTTTRSEW-LVKLLYAFQDPQSLYLAMEFVPGGDFRTLLLNTKFLQAPHARFY 275
+L E +I T + +V+LL F+D + YL ME + GG +L K+ AR
Sbjct: 244 ILREVNIFKTCKDHPNIVQLLDWFEDETNFYLVMEKMRGGPLLQHILQRKYFTEEEARRV 303
Query: 276 ISEMFCAVNALHQLGYTHRDLKPENFLIDSKGH---IKLTDFGLASGTVSMERIESMKIR 332
++ A+ +H G HRD+KPEN L H +KL D LAS
Sbjct: 304 TKDISLALKFMHDRGIAHRDVKPENVLCTDPNHVSPVKLCDLDLAS-------------- 349
Query: 333 LQEVKNLEFPEFRERSMDDRRRMYNKLREEEVRYAHSTVGSPDYMALEVLEA-----KNY 387
+R R +++ E S VGS ++MA EV++A Y
Sbjct: 350 -------------QRPPQHERHPLSQVASEP--DLASPVGSAEFMAPEVVDAYVGDSLKY 394
Query: 388 DFTVDYWSLGCILFESLVGYTPFSGNSTNETYENLRNWKHVLQRPKC--------DNGRY 439
D D WSLG IL+ L GY PF G +E W C +G Y
Sbjct: 395 DKKCDTWSLGVILYIMLAGYAPFQGMCDDEDC----GWSEGKPCEDCQQDLFHRIQDGYY 450
Query: 440 AFSDRTWELITRLIADPINRLKSFEHVKRM 469
F + W +I+ D ++ L + V R+
Sbjct: 451 EFPEEEWGMISEEAKDLVSNLLKRDPVDRL 480
>Hs4507273 [D] KOG0580 Serine/threonine protein kinase
Length = 275
Score = 87.8 bits (216), Expect = 4e-17
Identities = 67/253 (26%), Positives = 102/253 (39%), Gaps = 44/253 (17%)
Query: 171 DFEMITXXXXXXXXXXXLARKKDTKEICAXXXXXXXXXXXXEGTDHVLT-ERDILTTTRS 229
DFE+ LAR K++ I A EG +H L E +I +
Sbjct: 8 DFEIGRPLGKGKFGNVYLARLKESHFIVALKVLFKSQIEK-EGLEHQLRREIEIQAHLQH 66
Query: 230 EWLVKLLYAFQDPQSLYLAMEFVPGGDFRTLLLNTKFLQAPHARFYISEMFCAVNALHQL 289
+++L F D + +YL +E+ P G+ L ++ L I E+ A+ H
Sbjct: 67 PNILRLYNYFHDARRVYLILEYAPRGELYKELQKSEKLDEQRTATIIEEVADALTYCHDK 126
Query: 290 GYTHRDLKPENFLIDSKGHIKLTDFGLASGTVSMERIESMKIRLQEVKNLEFPEFRERSM 349
HRD+KPEN L+ +G +K+ DFG + T ER
Sbjct: 127 KVIHRDIKPENLLLGFRGEVKIADFGWSVHTPLPER------------------------ 162
Query: 350 DDRRRMYNKLREEEVRYAHSTVGSPDYMALEVLEAKNYDFTVDYWSLGCILFESLVGYTP 409
+ G+ DY+ E++E + YD VD W +G + +E LVGY P
Sbjct: 163 ------------------KTMCGTLDYLPPEMIEGRTYDEKVDLWCIGVLCYELLVGYPP 204
Query: 410 FSGNSTNETYENL 422
F S +ETY +
Sbjct: 205 FESASHSETYRRI 217
>7297776 [D] KOG0580 Serine/threonine protein kinase
Length = 329
Score = 87.8 bits (216), Expect = 4e-17
Identities = 68/257 (26%), Positives = 105/257 (40%), Gaps = 46/257 (17%)
Query: 170 KDFEMITXXXXXXXXXXXLARKKDTKEICAXXXXXXXXXXXXEGTDHVLTERDILTTTRS 229
+DFEM LAR++ + + A VL E +I + +
Sbjct: 51 RDFEMGAHLGRGKFGRVYLARERHSHYLVAMKVMFKEELRKGCVQRQVLREIEIQSRLKH 110
Query: 230 EWLVKLLYAFQDPQSLYLAMEFVPGGDFRTLLL---NTKFLQAPHARFYISEMFCAVNAL 286
+++LL F D +YLA+E G+ L N +F P + Y ++ A+N
Sbjct: 111 PHILRLLTWFHDESRIYLALEIASEGELFKHLRGAPNHRF-DEPRSAKYTYQVANALNYC 169
Query: 287 HQLGYTHRDLKPENFLIDSKGHIKLTDFGLASGTVSMERIESMKIRLQEVKNLEFPEFRE 346
H HRDLKPEN L+ S +KL DFG ++ T + +R
Sbjct: 170 HLNNVIHRDLKPENILLTSTDDLKLADFGWSAHTPNNKR--------------------- 208
Query: 347 RSMDDRRRMYNKLREEEVRYAHSTVGSPDYMALEVLEAKNYDFTVDYWSLGCILFESLVG 406
+ G+ DY+ E+++ +YD +VD W LG + +E +VG
Sbjct: 209 ---------------------RTLCGTLDYLPPEMVDGNSYDDSVDQWCLGILCYEFVVG 247
Query: 407 YTPFSGNSTNETYENLR 423
PF NST TY +R
Sbjct: 248 CPPFESNSTESTYSKIR 264
>At5g10930 [T] KOG0583 Serine/threonine protein kinase
Length = 445
Score = 87.0 bits (214), Expect = 7e-17
Identities = 71/248 (28%), Positives = 105/248 (41%), Gaps = 49/248 (19%)
Query: 215 DHVLTERDILTTTRSEWLVKLLYAFQDPQSLYLAMEFVPGGDFRTLLLNTKFLQAPHARF 274
+ + E I+ R +V+L ++ MEFV GG+ + K L AR
Sbjct: 56 EQIKREISIMKLVRHPNIVELKEVMATKTKIFFVMEFVKGGELFCKISKGK-LHEDAARR 114
Query: 275 YISEMFCAVNALHQLGYTHRDLKPENFLIDSKGHIKLTDFGLASGTVSMERIESMKIRLQ 334
Y ++ AV+ H G +HRDLKPEN L+D G +K++DFGL++
Sbjct: 115 YFQQLISAVDYCHSRGVSHRDLKPENLLLDENGDLKISDFGLSA---------------- 158
Query: 335 EVKNLEFPEFRERSMDDRRRMYNKLREEEVRYAHSTVGSPDYMALEVLEAKNYD-FTVDY 393
E+ + D H+ G+P Y+A EVL+ K YD D
Sbjct: 159 ---------LPEQILQD-------------GLLHTQCGTPAYVAPEVLKKKGYDGAKADI 196
Query: 394 WSLGCILFESLVGYTPFSGNSTNETYENLRNWKHVLQRPKCDNGRYAFSDRTWELITR-L 452
WS G +L+ L G PF ENL N + R + + FS LI++ L
Sbjct: 197 WSCGVVLYVLLAGCLPFQD-------ENLMNMYRKIFRADFEFPPW-FSPEARRLISKLL 248
Query: 453 IADPINRL 460
+ DP R+
Sbjct: 249 VVDPDRRI 256
>CE29020 [T] KOG0660 Mitogen-activated protein kinase
Length = 470
Score = 86.7 bits (213), Expect = 9e-17
Identities = 85/330 (25%), Positives = 146/330 (43%), Gaps = 46/330 (13%)
Query: 232 LVKLLYAFQ--DPQSLYLAMEFVPGGDFRTLLLNTKFLQAPHARFYISEMFCAVNALHQL 289
++KL F+ + + +YLA EF+ D ++ L+ H ++ + ++F A+ LH
Sbjct: 73 VIKLYNIFRADNDRDIYLAFEFMEA-DLHNVIKKGSILKDVHKQYIMCQLFRAIRFLHSG 131
Query: 290 GYTHRDLKPENFLIDSKGHIKLTDFGLASGTVSMERIESMKIRLQEVKNLEFPEFRERSM 349
HRDLKP N L+D+ +KL DFGLA S+E ++PE +
Sbjct: 132 NVLHRDLKPSNVLLDADCRVKLADFGLARSLSSLE---------------DYPEGQ---- 172
Query: 350 DDRRRMYNKLREEEVRYAHSTVGSPDYMALEVLEAKNYDFTVDYWSLGCILFESLVGYTP 409
K+ + A SP+ + L AK Y VD WSLGCIL E L+G
Sbjct: 173 --------KMPDLTEYVATRWYRSPEIL----LAAKRYTKGVDMWSLGCILAEMLIGRAL 220
Query: 410 FSGNSTNETYENLRNWKHVLQRPKCDNGRYAFSDRTWELITRLIADPI------NRLKSF 463
F G+ST E + N R + ++ E + + P+ ++ +
Sbjct: 221 FPGSSTINQIERIMNTIAKPSRADIASIGSHYAASVLEKMPQRPRKPLDLIITQSQTAAI 280
Query: 464 EHVKRMRYFSEIDFNTL-RTIHPPFIPQLDN--EEDVGYFDDFTN-EEHMARYVDVFKRQ 519
+ V+R+ F+ T+ + + P++ Q N EE V ++ + +H+ +D ++
Sbjct: 281 DMVQRLLIFAPQKRLTVEQCLVHPYVVQFHNPSEEPVLNYEVYPPLPDHIQLSIDDYR-- 338
Query: 520 DRLTAMVDDSLSDSKLVGFTFRHRNGKDGS 549
DRL M+D+ + K + G+D S
Sbjct: 339 DRLYEMIDEKKASFKRIQHEKIRPYGEDKS 368
>At1g01140 [T] KOG0583 Serine/threonine protein kinase
Length = 447
Score = 86.7 bits (213), Expect = 9e-17
Identities = 54/192 (28%), Positives = 87/192 (45%), Gaps = 39/192 (20%)
Query: 232 LVKLLYAFQDPQSLYLAMEFVPGGDFRTLLLNTKFLQAPHARFYISEMFCAVNALHQLGY 291
+V+++ +Y+ +E V GG+ + L+ AR Y ++ AV+ H G
Sbjct: 79 VVEIIEVMASKTKIYIVLELVNGGELFDKIAQQGRLKEDEARRYFQQLINAVDYCHSRGV 138
Query: 292 THRDLKPENFLIDSKGHIKLTDFGLASGTVSMERIESMKIRLQEVKNLEFPEFRERSMDD 351
HRDLKPEN ++D+ G +K++DFGL++
Sbjct: 139 YHRDLKPENLILDANGVLKVSDFGLSA--------------------------------- 165
Query: 352 RRRMYNKLREEEVRYAHSTVGSPDYMALEVLEAKNYD-FTVDYWSLGCILFESLVGYTPF 410
++RE+ + H+ G+P+Y+A EVL K YD D WS G ILF + GY PF
Sbjct: 166 ---FSRQVREDGL--LHTACGTPNYVAPEVLSDKGYDGAAADVWSCGVILFVLMAGYLPF 220
Query: 411 SGNSTNETYENL 422
+ Y+ +
Sbjct: 221 DEPNLMTLYKRI 232
>Hs22066167 [RT] KOG0598 Ribosomal protein S6 kinase and related proteins
Length = 147
Score = 86.3 bits (212), Expect = 1e-16
Identities = 44/108 (40%), Positives = 63/108 (57%)
Query: 214 TDHVLTERDILTTTRSEWLVKLLYAFQDPQSLYLAMEFVPGGDFRTLLLNTKFLQAPHAR 273
T H E +IL R ++V L YAFQ LYL +E++ GG+ L A
Sbjct: 9 TAHTKAEWNILEEVRHPFIVDLTYAFQTGGKLYLILEYLSGGELFMQLEREGIFMEDTAC 68
Query: 274 FYISEMFCAVNALHQLGYTHRDLKPENFLIDSKGHIKLTDFGLASGTV 321
FY++E+ A+ LHQ G +RDLKPEN +++ +GH+KLTDFGL ++
Sbjct: 69 FYLAEISMALGHLHQKGIIYRDLKPENIILNHQGHMKLTDFGLRKESI 116
>Hs14916455 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 385
Score = 86.3 bits (212), Expect = 1e-16
Identities = 75/270 (27%), Positives = 110/270 (39%), Gaps = 58/270 (21%)
Query: 212 EGTDHVLTERDILTTTRSEWLVKLLYAFQDPQSLYLAMEFVPGGD-FRTLLLNTKFLQAP 270
EG + ++E +L ++V+L+ F+ +Y+ ME GG+ F L+ F +
Sbjct: 100 EGREACVSELSVLRRVSHRYIVQLMEIFETEDQVYMVMELATGGELFDRLIAQGSFTERD 159
Query: 271 HARFYISEMFCAVNALHQLGYTHRDLKPENFLIDSKGH---IKLTDFGLA-SGTVSMERI 326
R + + + LH L THR+LKPEN L G I +TDFGLA SG S +
Sbjct: 160 AVRI-LQMVADGIRYLHALQITHRNLKPENLLYYHPGEESKILITDFGLAYSGKKSGD-- 216
Query: 327 ESMKIRLQEVKNLEFPEFRERSMDDRRRMYNKLREEEVRYAHSTVGSPDYMALEVLEAKN 386
+MK + G+P+Y+A EVL K
Sbjct: 217 WTMK--------------------------------------TLCGTPEYIAPEVLLRKP 238
Query: 387 YDFTVDYWSLGCILFESLVGYTPFSGNSTNETYENLRNWKHVLQRPKCDNGRYAFSDRTW 446
Y VD W+LG I + L G+ PF S Y K G+Y ++ W
Sbjct: 239 YTSAVDMWALGVITYALLSGFLPFDDESQTRLYR------------KILKGKYNYTGEPW 286
Query: 447 ELITRLIADPINRLKSFEHVKRMRYFSEID 476
I+ L D I++L E RM +D
Sbjct: 287 PSISHLAKDFIDKLLILEAGHRMSAGQALD 316
>CE17284 [T] KOG0583 Serine/threonine protein kinase
Length = 726
Score = 86.3 bits (212), Expect = 1e-16
Identities = 54/209 (25%), Positives = 91/209 (42%), Gaps = 38/209 (18%)
Query: 217 VLTERDILTTTRSEWLVKLLYAFQDPQSLYLAMEFVPGGDFRTLLLNTKFLQAPHARFYI 276
V TE D L + + +L + + ++ ME+ GG+ ++ + L+ AR +
Sbjct: 54 VQTEMDALRNLSHQNICRLYHYIETEDKFFIVMEYCSGGEMFDYIVRKERLEESEARHFF 113
Query: 277 SEMFCAVNALHQLGYTHRDLKPENFLIDSKGHIKLTDFGLASGTVSMERIESMKIRLQEV 336
++ A+ +H GY HRDLKPEN L+ H+KL DFGL + T
Sbjct: 114 RQLVSAIAFVHSQGYAHRDLKPENLLLTEDLHLKLIDFGLCAKT---------------- 157
Query: 337 KNLEFPEFRERSMDDRRRMYNKLREEEVRYAHSTVGSPDYMALEVLEAKNYDFT-VDYWS 395
E+ D+ + + GSP Y A E+++ Y D WS
Sbjct: 158 ---------EKGRIDKHNL------------DTCCGSPAYAAPELIQGLQYKGNEADVWS 196
Query: 396 LGCILFESLVGYTPFSGNSTNETYENLRN 424
+G +L+ LVG PF ++ Y+ +++
Sbjct: 197 MGILLYTLLVGALPFEDDNMQIMYKKIQS 225
>7298652 [D] KOG0615 Serine/threonine protein kinase Chk2 and related
proteins
Length = 459
Score = 86.3 bits (212), Expect = 1e-16
Identities = 70/260 (26%), Positives = 109/260 (41%), Gaps = 68/260 (26%)
Query: 215 DHVLTERDILTTTRSEWLVKLLYAFQDPQSLYLAMEFVPGGDFRTLLLNTKFLQAPHARF 274
D VL E I+ +V++ P S+Y+ +EF+ GGD +++ K L ++
Sbjct: 206 DRVLNEAKIMKNLSHPCVVRMHDIVDKPDSVYMVLEFMRGGDLLNRIISNKLLSEDISKL 265
Query: 275 YISEMFCAVNALHQLGYTHRDLKPENFLI---DSKGHIKLTDFGLASGTVSMERIESMKI 331
Y +M AV LH G THRDLKP+N L+ D + +K++DFGL+
Sbjct: 266 YFYQMCHAVKYLHDRGITHRDLKPDNVLLETNDEETLLKVSDFGLS-------------- 311
Query: 332 RLQEVKNLEFPEFRERSMDDRRRMYNKLREEEVRYAHSTVGSPDYMALEVL---EAKNYD 388
+F ++ R + G+P Y+A EVL + Y
Sbjct: 312 -----------KFVQKDSVMR----------------TLCGTPLYVAPEVLITGGREAYT 344
Query: 389 FTVDYWSLGCILFESLVGYTPFSGNSTNETYENLRNWKHVLQRPKCDNGRYAFSDRTWEL 448
VD WSLG +LF L G PFS + ++ GR+A+ +W+
Sbjct: 345 KKVDIWSLGVVLFTCLSGTLPFSDEYGTPAAQQIK------------KGRFAYGHPSWKS 392
Query: 449 ITR---------LIADPINR 459
+++ LI DP R
Sbjct: 393 VSQRAKLLINQMLIVDPERR 412
>7293666 [D] KOG0575 Polo-like serine/threonine protein kinase
Length = 576
Score = 86.3 bits (212), Expect = 1e-16
Identities = 54/208 (25%), Positives = 92/208 (43%), Gaps = 44/208 (21%)
Query: 232 LVKLLYAFQDPQSLYLAMEFVPGGDFRTLLLNTKFLQAPHARFYISEMFCAVNALHQLGY 291
+VK F+D Q++Y+ +E L K + R+YI ++ V LH
Sbjct: 85 IVKFHNYFEDSQNIYIVLELCKKRSMMELHKRRKSITEFECRYYIYQIIQGVKYLHDNRI 144
Query: 292 THRDLKPENFLIDSKGHIKLTDFGLASGTVSMERIESMKIRLQEVKNLEFPEFRERSMDD 351
HRDLK N ++ H+K+ DFGLA+ +E+ R++++
Sbjct: 145 IHRDLKLGNLFLNDLLHVKIGDFGLAT-------------------RIEYEGERKKTL-- 183
Query: 352 RRRMYNKLREEEVRYAHSTVGSPDYMALEVLEAKNYDFTVDYWSLGCILFESLVGYTPFS 411
G+P+Y+A E+L K + F VD WS+GC+++ LVG PF
Sbjct: 184 -------------------CGTPNYIAPEILTKKGHSFEVDIWSIGCVMYTLLVGQPPFE 224
Query: 412 GNSTNETYENLRNWKH----VLQRPKCD 435
+ +TY ++ ++ L++P D
Sbjct: 225 TKTLKDTYSKIKKCEYRVPSYLRKPAAD 252
>Hs5730055 [D] KOG0575 Polo-like serine/threonine protein kinase
Length = 685
Score = 85.9 bits (211), Expect = 2e-16
Identities = 50/198 (25%), Positives = 90/198 (45%), Gaps = 40/198 (20%)
Query: 232 LVKLLYAFQDPQSLYLAMEFVPGGDFRTLLLNTKFLQAPHARFYISEMFCAVNALHQLGY 291
+V+ + F+D +++Y+ +E+ +L K L P R+Y+ ++ + LH+
Sbjct: 142 VVQFYHYFEDKENIYILLEYCSRRSMAHILKARKVLTEPEVRYYLRQIVSGLKYLHEQEI 201
Query: 292 THRDLKPENFLIDSKGHIKLTDFGLASGTVSMERIESMKIRLQEVKNLEFPEFRERSMDD 351
HRDLK NF I+ +K+ DFGLA+ R ++
Sbjct: 202 LHRDLKLGNFFINEAMELKVGDFGLAA--------------------------RLEPLEH 235
Query: 352 RRRMYNKLREEEVRYAHSTVGSPDYMALEVLEAKNYDFTVDYWSLGCILFESLVGYTPFS 411
RRR + G+P+Y++ EVL + + D W+LGC+++ L+G PF
Sbjct: 236 RRR--------------TICGTPNYLSPEVLNKQGHGCESDIWALGCVMYTMLLGRPPFE 281
Query: 412 GNSTNETYENLRNWKHVL 429
+ ETY +R ++ +
Sbjct: 282 TTNLKETYRCIREARYTM 299
>Hs14754789 [OUT] KOG0595 Serine/threonine-protein kinase involved in autophagy
Length = 257
Score = 85.9 bits (211), Expect = 2e-16
Identities = 64/213 (30%), Positives = 93/213 (43%), Gaps = 44/213 (20%)
Query: 191 KKDTKEICAXXXXXXXXXXXXEGTDHVLTERDILTTTRSEWLVKLLYAFQDPQSLYLAME 250
KKDT+E+ A +++LTE +IL R +V+L D ++YL ME
Sbjct: 77 KKDTREVVAIKCVAKKSLNKAS-VENLLTEIEILKGIRHPHIVQLKDFQWDSDNIYLIME 135
Query: 251 FVPGGDFRTLLLNTKFLQAPHARFYISEMFCAVNALHQLGYTHRDLKPENFLIDS--KGH 308
F GGD + + L AR ++ ++ A+ LH+ +H DLKP+N L+ S K H
Sbjct: 136 FCAGGDLSRFIHTRRILPEKVARVFMQQLASALQFLHERNISHLDLKPQNILLSSLEKPH 195
Query: 309 IKLTDFGLASGTVSMERIESMKIRLQEVKNLEFPEFRERSMDDRRRMYNKLREEEVRYAH 368
+KL DFG A + S D + H
Sbjct: 196 LKLADFGFA---------------------------QHMSPWDEK--------------H 214
Query: 369 STVGSPDYMALEVLEAKNYDFTVDYWSLGCILF 401
GSP YMA E++ + YD VD WS+G IL+
Sbjct: 215 VLRGSPLYMAPEMVCQRQYDARVDLWSMGVILY 247
>CE24761 [D] KOG0580 Serine/threonine protein kinase
Length = 305
Score = 85.5 bits (210), Expect = 2e-16
Identities = 56/212 (26%), Positives = 93/212 (43%), Gaps = 43/212 (20%)
Query: 213 GTDHVLT-ERDILTTTRSEWLVKLLYAFQDPQSLYLAMEFVPGGDFRTLLLNTKFLQAPH 271
G +H L E +I + ++KL F D + +YL +E+ PGG+ L +K P
Sbjct: 70 GVEHQLEREIEIQSHLNHPNIIKLYTYFWDAKKIYLVLEYAPGGEMYKQLTVSKRFSEPT 129
Query: 272 ARFYISEMFCAVNALHQLGYTHRDLKPENFLIDSKGHIKLTDFGLASGTVSMERIESMKI 331
A Y+ E+ A++ H+ HRD+KPEN LI S+G +K+ DFG + S +R
Sbjct: 130 AAKYMYEIADALSYCHRKNVIHRDIKPENLLIGSQGELKIGDFGWSVHAPSNKR------ 183
Query: 332 RLQEVKNLEFPEFRERSMDDRRRMYNKLREEEVRYAHSTVGSPDYMALEVLEAKNYDFTV 391
+ G+ DY+ E++ ++ V
Sbjct: 184 ------------------------------------QTMCGTMDYLPPEMVNGADHSDAV 207
Query: 392 DYWSLGCILFESLVGYTPFSGNSTNETYENLR 423
D W++G + +E LVG PF ++TY ++
Sbjct: 208 DLWAIGVLCYEFLVGKPPFEHEDQSKTYAAIK 239
>YPL150w [T] KOG0583 Serine/threonine protein kinase
Length = 901
Score = 85.1 bits (209), Expect = 3e-16
Identities = 64/239 (26%), Positives = 99/239 (40%), Gaps = 49/239 (20%)
Query: 231 WLVKLLYAFQDPQSLYLAMEFVPGGDFRTLLLNTKFLQAPHARFYISEMFCAVNALHQLG 290
++ KL +++A+E+ PG + LL+ + + +++ AV H +
Sbjct: 93 YITKLYEVIVTESKVWMALEYCPGKELYDHLLSLRRISLLECGELFAQISGAVYYAHSMH 152
Query: 291 YTHRDLKPENFLIDSKGHIKLTDFGLASGTVSMERIESMKIRLQEVKNLEFPEFRERSMD 350
HRDLK EN L+D G+ KLTDFG ++ +E++
Sbjct: 153 CVHRDLKLENILLDKNGNAKLTDFGFTRECMTKTTLETV--------------------- 191
Query: 351 DRRRMYNKLREEEVRYAHSTVGSPDYMALEVLEAKNYD-FTVDYWSLGCILFESLVGYTP 409
G+ YMA E++E + YD F +D WSLG IL+ + GY P
Sbjct: 192 --------------------CGTTVYMAPELIERRTYDGFKIDIWSLGVILYTLITGYLP 231
Query: 410 FSGNSTNETYENLRNWKHVLQRPKCDNGRYAFSDRTWELITRLIADPINRLKSFEHVKR 468
F + +T WK V + PK D D +LI+RL+A S V R
Sbjct: 232 FDDDDEAKT-----KWKIVNEEPKYD--AKVIPDDARDLISRLLAKNPGERPSLSQVLR 283
>HsM4507279 [D] KOG0580 Serine/threonine protein kinase
Length = 402
Score = 84.7 bits (208), Expect = 3e-16
Identities = 70/255 (27%), Positives = 107/255 (41%), Gaps = 46/255 (18%)
Query: 170 KDFEMITXXXXXXXXXXXLARKKDTKEICAXXXXXXXXXXXXEGTDHVLT-ERDILTTTR 228
+DFE+ LAR+K +K I A G +H L E +I + R
Sbjct: 130 EDFEIGRPLGKGKFGNVYLAREKQSKFILALKVLFKAQLEKA-GVEHQLRREVEIQSHLR 188
Query: 229 SEWLVKLLYAFQDPQSLYLAMEFVPGGD-FRTLLLNTKFLQAPHARFYISEMFCAVNALH 287
+++L F D +YL +E+ P G +R L +KF + A Y + + A++ H
Sbjct: 189 HPNILRLYGYFHDATRVYLILEYAPLGTVYRELQKLSKFDEQRTANLY-NRIANALSYCH 247
Query: 288 QLGYTHRDLKPENFLIDSKGHIKLTDFGLASGTVSMERIESMKIRLQEVKNLEFPEFRER 347
HRD+KPEN L+ S G +K+ DFG + S R
Sbjct: 248 SKRVIHRDIKPENLLLGSAGELKIADFGWSVHAPSSRRT--------------------- 286
Query: 348 SMDDRRRMYNKLREEEVRYAHSTVGSPDYMALEVLEAKNYDFTVDYWSLGCILFESLVGY 407
+ G+ DY+ E++E + +D VD WSLG + +E LVG
Sbjct: 287 ---------------------TLCGTLDYLPPEMIEGRMHDEKVDLWSLGVLCYEFLVGK 325
Query: 408 TPFSGNSTNETYENL 422
PF N+ ETY+ +
Sbjct: 326 PPFEANTYQETYKRI 340
>At3g17510 [T] KOG0583 Serine/threonine protein kinase
Length = 446
Score = 84.7 bits (208), Expect = 3e-16
Identities = 73/274 (26%), Positives = 115/274 (41%), Gaps = 59/274 (21%)
Query: 232 LVKLLYAFQDPQSLYLAMEFVPGGDFRTLLLNTKFLQAPHARFYISEMFCAVNALHQLGY 291
+V+L + + ME V GG+ +++ L R ++ ++ H G
Sbjct: 80 IVRLHEVLASKTKINMVMELVTGGELFDRIVSNGKLTETDGRKMFQQLIDGISYCHSKGV 139
Query: 292 THRDLKPENFLIDSKGHIKLTDFGLASGTVSMERIESMKIRLQEVKNLEFPE-FRERSMD 350
HRDLK EN L+D+KGHIK+TDFGL++ P+ FR+ +
Sbjct: 140 FHRDLKLENVLLDAKGHIKITDFGLSA----------------------LPQHFRDDGL- 176
Query: 351 DRRRMYNKLREEEVRYAHSTVGSPDYMALEVLEAKNYDFTV-DYWSLGCILFESLVGYTP 409
H+T GSP+Y+A EVL + YD D WS G IL+ L G P
Sbjct: 177 ----------------LHTTCGSPNYVAPEVLANRGYDGAASDIWSCGVILYVILTGCLP 220
Query: 410 FSGNSTNETYENLRNWKHVLQRPKCDNGRYAFSDRTWELITRLI-ADPINRLKSFEHVKR 468
F + Y+ + + R R +I R++ +P+ R+ + +K
Sbjct: 221 FDDRNLAVLYQKICKGDPPIPRWLSPGAR--------TMIKRMLDPNPVTRI-TVVGIKA 271
Query: 469 MRYFSEIDFNTLRTIHPPFIPQLDNEEDVGYFDD 502
+F + + P IP D+EE+V DD
Sbjct: 272 SEWF--------KLEYIPSIPDDDDEEEVDTDDD 297
>At3g01090 [T] KOG0583 Serine/threonine protein kinase
Length = 512
Score = 84.7 bits (208), Expect = 3e-16
Identities = 67/251 (26%), Positives = 104/251 (40%), Gaps = 51/251 (20%)
Query: 212 EGTDHVLTERDILTTTRSEWLVKLLYAFQDPQSLYLAMEFVPGGDFRTLLLNTKFLQAPH 271
E + V E IL +++L + P +YL ME+V G+ ++ LQ
Sbjct: 59 EMEEKVRREIKILRLFMHPHIIRLYEVIETPTDIYLVMEYVNSGELFDYIVEKGRLQEDE 118
Query: 272 ARFYISEMFCAVNALHQLGYTHRDLKPENFLIDSKGHIKLTDFGLASGTVSMERIESMKI 331
AR + ++ V H+ HRDLKPEN L+DSK ++K+ DFGL+
Sbjct: 119 ARNFFQQIISGVEYCHRNMVVHRDLKPENLLLDSKCNVKIADFGLS-------------- 164
Query: 332 RLQEVKNLEFPEFRERSMDDRRRMYNKLREEEVRYAHSTVGSPDYMALEVLEAKNY-DFT 390
N +R+ + ++ GSP+Y A EV+ K Y
Sbjct: 165 -------------------------NIMRDG--HFLKTSCGSPNYAAPEVISGKLYAGPE 197
Query: 391 VDYWSLGCILFESLVGYTPFSGNSTNETYENLRNWKHVLQRPKCDNGRYAFSDRTWELIT 450
VD WS G IL+ L G PF + ++ ++ + L R +LI
Sbjct: 198 VDVWSCGVILYALLCGTLPFDDENIPNLFKKIKGGIYTLPSHLSPGAR--------DLIP 249
Query: 451 R-LIADPINRL 460
R L+ DP+ R+
Sbjct: 250 RMLVVDPMKRV 260
>Hs7657214 [T] KOG0583 Serine/threonine protein kinase
Length = 714
Score = 84.3 bits (207), Expect = 4e-16
Identities = 58/198 (29%), Positives = 82/198 (41%), Gaps = 38/198 (19%)
Query: 214 TDHVLTERDILTTTRSEWLVKLLYAFQDPQSLYLAMEFVPGGDFRTLLLNTKFLQAPHAR 273
T ++ E I R + +LL + S YL ME PGG+ + K L+ AR
Sbjct: 105 TKNLRREGQIQQMIRHPNITQLLDILETENSYYLVMELCPGGNLMHKIYEKKRLEESEAR 164
Query: 274 FYISEMFCAVNALHQLGYTHRDLKPENFLIDSKGHIKLTDFGLASGTVSMERIESMKIRL 333
YI ++ AV LH+ G HRDLK EN L+D +IKL DFGL++ + +
Sbjct: 165 RYIRQLISAVEHLHRAGVVHRDLKIENLLLDEDNNIKLIDFGLSNCAGILGYSDPFS--- 221
Query: 334 QEVKNLEFPEFRERSMDDRRRMYNKLREEEVRYAHSTVGSPDYMALEVLEAKNYDFTVDY 393
+ GSP Y A E+L K Y +D
Sbjct: 222 -----------------------------------TQCGSPAYAAPELLARKKYGPKIDV 246
Query: 394 WSLGCILFESLVGYTPFS 411
WS+G ++ L G PF+
Sbjct: 247 WSIGVNMYAMLTGTLPFT 264
>At3g23000 [T] KOG0583 Serine/threonine protein kinase
Length = 429
Score = 84.3 bits (207), Expect = 4e-16
Identities = 62/237 (26%), Positives = 97/237 (40%), Gaps = 41/237 (17%)
Query: 188 LARKKDTKEICAXXXXXXXXXXXXEGTDHVLTERDILTTTRSEW-LVKLLYAFQDPQSLY 246
LAR ++ E+ A ++ E D + R ++K+ +Y
Sbjct: 41 LARSIESDELVAVKIIEKKKTIESGMEPRIIREIDAMRRLRHHPNILKIHEVMATKSKIY 100
Query: 247 LAMEFVPGGDFRTLLLNTKFLQAPHARFYISEMFCAVNALHQLGYTHRDLKPENFLIDSK 306
L ME GG+ + +L L AR Y ++ A+ HQ G HRD+KP+N L+D +
Sbjct: 101 LVMELASGGELFSKVLRRGRLPESTARRYFQQLASALRFSHQDGVAHRDVKPQNLLLDEQ 160
Query: 307 GHIKLTDFGLASGTVSMERIESMKIRLQEVKNLEFPEFRERSMDDRRRMYNKLREEEVRY 366
G++K++DFGL++ PE + +
Sbjct: 161 GNLKVSDFGLSA----------------------LPEHLQNGL----------------- 181
Query: 367 AHSTVGSPDYMALEVLEAKNYD-FTVDYWSLGCILFESLVGYTPFSGNSTNETYENL 422
H+ G+P Y A EV+ + YD D WS G ILF LVG PF ++ Y +
Sbjct: 182 LHTACGTPAYTAPEVISRRGYDGAKADAWSCGVILFVLLVGDVPFDDSNIAAMYRKI 238
>7299536 [D] KOG0580 Serine/threonine protein kinase
Length = 411
Score = 84.3 bits (207), Expect = 4e-16
Identities = 69/243 (28%), Positives = 104/243 (42%), Gaps = 56/243 (23%)
Query: 188 LARKKDTKEICAXXXXXXXXXXXXEGTDHVLTERDILTTTRSEWLVKLLYAFQDPQSLYL 247
LAR+K+++ + A V E +I + R +++L F D +YL
Sbjct: 170 LAREKESQFVVALKVLFKRQIGESNVEHQVRREIEIQSHLRHPHILRLYAYFHDDVRIYL 229
Query: 248 AMEFVPGGDFRTLLLNTKFLQA-PHARF-------YISEMFCAVNALHQLGYTHRDLKPE 299
+E+ P G L N LQA P RF YI + A+ LH+ HRD+KPE
Sbjct: 230 ILEYAPQGT----LFNA--LQAQPMKRFDERQSATYIQALCSALLYLHERDIIHRDIKPE 283
Query: 300 NFLIDSKGHIKLTDFGLASGTVSMERIESMKIRLQEVKNLEFPEFRERSMDDRRRMYNKL 359
N L+ KG +K+ DFG S+ SM++ L
Sbjct: 284 NLLLGHKGVLKIADFGW-----SVHEPNSMRMTL-------------------------- 312
Query: 360 REEEVRYAHSTVGSPDYMALEVLEAKNYDFTVDYWSLGCILFESLVGYTPFSGNSTNETY 419
G+ DY+ E+++ K + VD WSLG + FE LVG+ PF + +ETY
Sbjct: 313 -----------CGTVDYLPPEMVQGKPHTKNVDLWSLGVLCFELLVGHAPFYSKNYDETY 361
Query: 420 ENL 422
+ +
Sbjct: 362 KKI 364
>YPL209c [D] KOG0580 Serine/threonine protein kinase
Length = 367
Score = 84.0 bits (206), Expect = 6e-16
Identities = 69/271 (25%), Positives = 108/271 (39%), Gaps = 46/271 (16%)
Query: 157 TNILRKRRLKPKHK-----DFEMITXXXXXXXXXXXLARKKDTKEICAXXXXXXXXXXXX 211
+ ++ + + PK K DFE+ R + T ICA
Sbjct: 84 SKMIHENKKLPKFKSLSLDDFELGKKLGKGKFGKVYCVRHRSTGYICALKVMEKEEIIKY 143
Query: 212 EGTDHVLTERDILTTTRSEWLVKLLYAFQDPQSLYLAMEFVPGGDFRTLLLNTKFLQAPH 271
E +I T+ L K F D + +YL ME++ G+ LL
Sbjct: 144 NLQKQFRREVEIQTSLNHPNLTKSYGYFHDEKRVYLLMEYLVNGEMYKLLRLHGPFNDIL 203
Query: 272 ARFYISEMFCAVNALHQLGYTHRDLKPENFLIDSKGHIKLTDFGLASGTVSMERIESMKI 331
A YI ++ A++ +H+ HRD+KPEN LI IKLTDFG +
Sbjct: 204 ASDYIYQIANALDYMHKKNIIHRDIKPENILIGFNNVIKLTDFGWSI------------- 250
Query: 332 RLQEVKNLEFPEFRERSMDDRRRMYNKLREEEVRYAHSTVGSPDYMALEVLEAKNYDFTV 391
+ PE R +++ G+ DY++ E++E++ YD T+
Sbjct: 251 -------INPPENRRKTV---------------------CGTIDYLSPEMVESREYDHTI 282
Query: 392 DYWSLGCILFESLVGYTPFSGNSTNETYENL 422
D W+LG + FE L G PF + TY+ +
Sbjct: 283 DAWALGVLAFELLTGAPPFEEEMKDTTYKRI 313
>SPCC1259.13 [D] KOG0590 Checkpoint kinase and related serine/threonine protein
kinases
Length = 496
Score = 84.0 bits (206), Expect = 6e-16
Identities = 66/233 (28%), Positives = 106/233 (45%), Gaps = 54/233 (23%)
Query: 240 QDPQSLYLAMEFVPGGDFRTLLLNTKFLQAPHARFYISEMFCAVNALHQLGYTHRDLKPE 299
++PQ ++ +EF GGD + + A+FY +++ ++ +H G HRDLKPE
Sbjct: 82 ENPQWRWVVLEFAQGGDLFDKIEPDVGIDEDVAQFYFAQLMEGISFMHSKGVAHRDLKPE 141
Query: 300 NFLIDSKGHIKLTDFGLASGTVSMERIESMKIRLQEVKNLEFPEFRERSMDDRRRMYNKL 359
N L+D G++K++DFG AS ++ +S
Sbjct: 142 NILLDYNGNLKISDFGFAS----------------------LFSYKGKS----------- 168
Query: 360 REEEVRYAHSTVGSPDYMALEVLEAKNYDFT-VDYWSLGCILFESLVGYTPFSGNSTNET 418
R +S VGSP Y A E+ + YD + VD WS G ILF L+G TP+ +N
Sbjct: 169 -----RLLNSPVGSPPYAAPEI--TQQYDGSKVDVWSCGIILFALLLGNTPWDEAISN-- 219
Query: 419 YENLRNWKHVLQRPKCDNGRY----AFSDRTWELITRLI-ADPINRLKSFEHV 466
++L + +C+ Y S + +IT ++ +DP R S +HV
Sbjct: 220 -----TGDYLLYKKQCERPSYHPWNLLSPGAYSIITGMLRSDPFKRY-SVKHV 266
>Hs4758016 [D] KOG0575 Polo-like serine/threonine protein kinase
Length = 607
Score = 84.0 bits (206), Expect = 6e-16
Identities = 55/215 (25%), Positives = 92/215 (42%), Gaps = 40/215 (18%)
Query: 215 DHVLTERDILTTTRSEWLVKLLYAFQDPQSLYLAMEFVPGGDFRTLLLNTKFLQAPHARF 274
+ +L E ++ + +V+ + F+D ++Y+ +E + L P R+
Sbjct: 66 EKILNEIELHRDLQHRHIVRFSHHFEDADNIYIFLELCSRKSLAHIWKARHTLLEPEVRY 125
Query: 275 YISEMFCAVNALHQLGYTHRDLKPENFLIDSKGHIKLTDFGLASGTVSMERIESMKIRLQ 334
Y+ ++ + LHQ G HRDLK NF I +K+ DFGLA+
Sbjct: 126 YLRQILSGLKYLHQRGILHRDLKLGNFFITENMELKVGDFGLAA---------------- 169
Query: 335 EVKNLEFPEFRERSMDDRRRMYNKLREEEVRYAHSTVGSPDYMALEVLEAKNYDFTVDYW 394
LE PE R++++ G+P+Y+A EVL + + D W
Sbjct: 170 ---RLEPPEQRKKTI---------------------CGTPNYVAPEVLLRQGHGPEADVW 205
Query: 395 SLGCILFESLVGYTPFSGNSTNETYENLRNWKHVL 429
SLGC+++ L G PF ETY ++ + L
Sbjct: 206 SLGCVMYTLLCGSPPFETADLKETYRCIKQVHYTL 240
>Hs20545245 [D] KOG0588 Serine/threonine protein kinase
Length = 795
Score = 84.0 bits (206), Expect = 6e-16
Identities = 57/202 (28%), Positives = 87/202 (42%), Gaps = 42/202 (20%)
Query: 223 ILTTTRSEWLVKLLYAFQDPQSLYLAMEFVPGGDFRTLLLNTKFLQAPHARFYISEMFCA 282
IL ++KL +++ + LYL +E V GG+ L+ L AR + ++ A
Sbjct: 101 ILKLIEHPHVLKLHDVYENKKYLYLVLEHVSGGELFDYLVKKGRLTPKEARKFFRQIVSA 160
Query: 283 VNALHQLGYTHRDLKPENFLIDSKGHIKLTDFGLASGTVSMERIESMKIRLQEVKNLEFP 342
++ H HRDLKPEN L+D K +I++ DFG+AS V +E
Sbjct: 161 LDFCHSYSICHRDLKPENLLLDEKNNIRIADFGMASLQVGDSLLE--------------- 205
Query: 343 EFRERSMDDRRRMYNKLREEEVRYAHSTVGSPDYMALEVLEAKNYD-FTVDYWSLGCILF 401
++ GSP Y EV++ + YD D WS G ILF
Sbjct: 206 --------------------------TSCGSPHYACPEVIKGEKYDGRRADMWSCGVILF 239
Query: 402 ESLVGYTPFSGNSTNETYENLR 423
LVG PF ++ + E ++
Sbjct: 240 ALLVGALPFDDDNLRQLLEKVK 261
>At2g25880 [D] KOG0580 Serine/threonine protein kinase
Length = 282
Score = 84.0 bits (206), Expect = 6e-16
Identities = 60/235 (25%), Positives = 99/235 (41%), Gaps = 43/235 (18%)
Query: 188 LARKKDTKEICAXXXXXXXXXXXXEGTDHVLTERDILTTTRSEWLVKLLYAFQDPQSLYL 247
LAR+K + I A + + E +I + R +++L F D + +YL
Sbjct: 35 LAREKRSDHIVALKVLFKAQLQQSQVEHQLRREVEIQSHLRHPNILRLYGYFYDQKRVYL 94
Query: 248 AMEFVPGGDFRTLLLNTKFLQAPHARFYISEMFCAVNALHQLGYTHRDLKPENFLIDSKG 307
+E+ G+ L K+ A Y++ + A+ H HRD+KPEN LI ++G
Sbjct: 95 ILEYAVRGELYKELQKCKYFSERRAATYVASLARALIYCHGKHVIHRDIKPENLLIGAQG 154
Query: 308 HIKLTDFGLASGTVSMERIESMKIRLQEVKNLEFPEFRERSMDDRRRMYNKLREEEVRYA 367
+K+ DFG + T + R R+M
Sbjct: 155 ELKIADFGWSVHTFN----------------------RRRTM------------------ 174
Query: 368 HSTVGSPDYMALEVLEAKNYDFTVDYWSLGCILFESLVGYTPFSGNSTNETYENL 422
G+ DY+ E++E+ +D +VD WSLG + +E L G PF +ETY+ +
Sbjct: 175 ---CGTLDYLPPEMVESVEHDASVDIWSLGILCYEFLYGVPPFEAREHSETYKRI 226
>At5g39440 [T] KOG0583 Serine/threonine protein kinase
Length = 494
Score = 83.6 bits (205), Expect = 7e-16
Identities = 65/258 (25%), Positives = 104/258 (40%), Gaps = 51/258 (19%)
Query: 217 VLTERDILTTTRSEWLVKLLYAFQDPQSLYLAMEFVPGGDFRTLLLNTKFLQAPHARFYI 276
V E IL +++ + P +Y+ ME+V G+ ++ LQ AR
Sbjct: 64 VQREIKILRFLMHPHIIRQYEVIETPNDIYVVMEYVKSGELFDYIVEKGKLQEDEARHLF 123
Query: 277 SEMFCAVNALHQLGYTHRDLKPENFLIDSKGHIKLTDFGLASGTVSMERIESMKIRLQEV 336
++ V H+ HRDLKPEN L+DS+ +IK+ DFGL++
Sbjct: 124 QQIISGVEYCHRNMIVHRDLKPENVLLDSQCNIKIVDFGLSNVM---------------- 167
Query: 337 KNLEFPEFRERSMDDRRRMYNKLREEEVRYAHSTVGSPDYMALEVLEAKNYDFTVDYWSL 396
+ + ++ GSP+Y A EV+ K Y VD WS
Sbjct: 168 -------------------------HDGHFLKTSCGSPNYAAPEVISGKPYGPDVDIWSC 202
Query: 397 GCILFESLVGYTPFSGNSTNETYENLRNWKHVLQRPKCDNGRYAFSDRTWELITR-LIAD 455
G IL+ L G PF + +E ++ + L R +LI R L+ D
Sbjct: 203 GVILYALLCGTLPFDDENIPNVFEKIKRGMYTLPNHLSHFAR--------DLIPRMLMVD 254
Query: 456 PINRLKSFEHVKRMRYFS 473
P R+ S +++ +F+
Sbjct: 255 PTMRI-SITEIRQHPWFN 271
>At2g37840 [OUT] KOG0595 Serine/threonine-protein kinase involved in autophagy
Length = 257
Score = 83.6 bits (205), Expect = 7e-16
Identities = 53/211 (25%), Positives = 93/211 (43%), Gaps = 44/211 (20%)
Query: 215 DHVLTERDILTTTRSEWLVKLLYAFQDPQSLYLAMEFVPGGDFRTLLLNTKFLQAPHARF 274
+ +++E IL +++L+ + P ++L +E+ GGD + + A+
Sbjct: 54 ESLMSEIFILRRINHPNIIRLIDMIKSPGKVHLVLEYCKGGDLSVYVQRHGIVPEATAKH 113
Query: 275 YISEMFCAVNALHQLGYTHRDLKPENFLI---DSKGHIKLTDFGLASGTVSMERIESMKI 331
++ ++ + L HRDLKP+N L+ ++ +K+ DFG A
Sbjct: 114 FMQQLAAGLQVLRDNNIIHRDLKPQNLLLSTNENDADLKIADFGFA-------------- 159
Query: 332 RLQEVKNLEFPEFRERSMDDRRRMYNKLREEEVRYAHSTVGSPDYMALEVLEAKNYDFTV 391
RS+ R A + GSP YMA E+++ + YD
Sbjct: 160 ---------------RSLQPRG------------LAETLCGSPLYMAPEIMQLQKYDAKA 192
Query: 392 DYWSLGCILFESLVGYTPFSGNSTNETYENL 422
D WS+G ILF+ + G TPF+GNS + +N+
Sbjct: 193 DLWSVGAILFQLVTGRTPFTGNSQIQLLQNI 223
>At1g12680 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 470
Score = 83.6 bits (205), Expect = 7e-16
Identities = 66/259 (25%), Positives = 108/259 (41%), Gaps = 55/259 (21%)
Query: 212 EGTDHVLTERDILTTTRSEWLVKLLYA-FQDPQSLYLAMEFVPGGDFRTLLLNTKFLQAP 270
+G + V E +I+ V L+A +++ +L ME GG ++
Sbjct: 140 KGEETVHREVEIMQHLSGHPRVVTLHAVYEESDCFHLVMELCSGGRLIDQMVKVGRYSEQ 199
Query: 271 HARFYISEMFCAVNALHQLGYTHRDLKPENFLIDSKGHIKLTDFGLASGTVSMERIESMK 330
A ++ +N H++G HRD+KPEN L+ + G I+L DFGLA
Sbjct: 200 RAANIFKDLMLVINYCHEMGVVHRDIKPENILLTAAGKIQLADFGLA------------- 246
Query: 331 IRLQEVKNLEFPEFRERSMDDRRRMYNKLREEEVRYAHSTVGSPDYMALEVLEAKNYDFT 390
+R+ + + L GSP Y+A EVL ++NY
Sbjct: 247 MRIAKGQTLS----------------------------GLAGSPAYVAPEVL-SENYSEK 277
Query: 391 VDYWSLGCILFESLVGYTPFSGNSTNETYENLRNWKHVLQRPKCDNGRYAFSDRTWELIT 450
VD WS G +L+ L G PF G+S + +E ++N K F+ WE ++
Sbjct: 278 VDVWSAGVLLYALLSGVLPFKGDSLDAIFEAIKNVK------------LDFNTGVWESVS 325
Query: 451 RLIADPINRLKSFEHVKRM 469
+ D + R+ + E R+
Sbjct: 326 KPARDLLARMLTREESARI 344
>ECU07g0520 [T] KOG0616 cAMP-dependent protein kinase catalytic subunit (PKA)
Length = 322
Score = 83.2 bits (204), Expect = 1e-15
Identities = 72/248 (29%), Positives = 103/248 (41%), Gaps = 56/248 (22%)
Query: 247 LAMEFVPGGDFRTLLLNTKFLQAPHARFYISEMFCAVNALHQLGYTHRDLKPENFLIDSK 306
L ME+V GG+ L ARFY +E+ A+ +H G +RDLKPEN LI S
Sbjct: 84 LIMEYVGGGELFYWLKKCGRFDEQMARFYAAEIISALRFIHGRGILYRDLKPENILITST 143
Query: 307 GHIKLTDFGLASGTVSMERIESMKIRLQEVKNLEFPEFRERSMDDRRRMYNKLREEEVRY 366
GHIKL DFG + + E +N+
Sbjct: 144 GHIKLIDFGFS---------------VYESENI--------------------------- 161
Query: 367 AHSTVGSPDYMALEVLEAKNYDFTVDYWSLGCILFESLVGYTPFSGNSTNETYENLRNWK 426
+ G+P+YM+ E L +++ DYW LG +++E L G PF +S + Y +
Sbjct: 162 -YMISGTPEYMSPEKLRSEDDGRASDYWGLGVMIYEMLCGDPPFYDSSADAIYHKILESN 220
Query: 427 HVLQRPKCDNGRYAFSDRTWELITRLI-ADPINRL--KSFEHVKRMRYFSEIDFNTL--R 481
V R LIT L+ + RL K + +F ID++ + R
Sbjct: 221 VVFPHYVSPVARC--------LITGLLDKNRATRLGTKGICEIMGHPFFKGIDWHEVESR 272
Query: 482 TIHPPFIP 489
I PPFIP
Sbjct: 273 RIEPPFIP 280
>At4g14580 [T] KOG0583 Serine/threonine protein kinase
Length = 426
Score = 83.2 bits (204), Expect = 1e-15
Identities = 53/192 (27%), Positives = 83/192 (42%), Gaps = 39/192 (20%)
Query: 232 LVKLLYAFQDPQSLYLAMEFVPGGDFRTLLLNTKFLQAPHARFYISEMFCAVNALHQLGY 291
++K+ +YL +E+ GG+ T L+ L AR Y ++ A++ H+ G
Sbjct: 82 VLKIHEVMATKSKIYLVVEYAAGGELFTKLIRFGRLNESAARRYFQQLASALSFCHRDGI 141
Query: 292 THRDLKPENFLIDSKGHIKLTDFGLASGTVSMERIESMKIRLQEVKNLEFPEFRERSMDD 351
HRD+KP+N L+D +G++K++DFGL++ PE R +
Sbjct: 142 AHRDVKPQNLLLDKQGNLKVSDFGLSA----------------------LPEHRSNN--- 176
Query: 352 RRRMYNKLREEEVRYAHSTVGSPDYMALEVLEAKNYD-FTVDYWSLGCILFESLVGYTPF 410
H+ G+P Y A EV+ + YD D WS G LF L GY PF
Sbjct: 177 -------------GLLHTACGTPAYTAPEVIAQRGYDGAKADAWSCGVFLFVLLAGYVPF 223
Query: 411 SGNSTNETYENL 422
+ Y +
Sbjct: 224 DDANIVAMYRKI 235
>Hs7706286 [T] KOG0033 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 489
Score = 82.8 bits (203), Expect = 1e-15
Identities = 69/260 (26%), Positives = 102/260 (38%), Gaps = 57/260 (21%)
Query: 215 DHVLTERD--ILTTTRSEWLVKLLYAFQDPQSLYLAMEFVPGGDFRTLLLNTKFLQAPHA 272
DH ER+ I + +V+L + + YL + V GG+ ++ ++ A
Sbjct: 53 DHQKLEREARICRLLKHPNIVRLHDSISEEGHHYLIFDLVTGGELFEDIVAREYYSEADA 112
Query: 273 RFYISEMFCAVNALHQLGYTHRDLKPENFLIDSK---GHIKLTDFGLASGTVSMERIESM 329
I ++ AV HQ+G HRDLKPEN L+ SK +KL DFGLA
Sbjct: 113 SHCIQQILEAVLHCHQMGVVHRDLKPENLLLASKLKGAAVKLADFGLAIEV--------- 163
Query: 330 KIRLQEVKNLEFPEFRERSMDDRRRMYNKLREEEVRYAHSTVGSPDYMALEVLEAKNYDF 389
E E + G+P Y++ EVL Y
Sbjct: 164 -------------------------------EGEQQAWFGFAGTPGYLSPEVLRKDPYGK 192
Query: 390 TVDYWSLGCILFESLVGYTPFSGNSTNETYENLRNWKHVLQRPKCDNGRYAFSDRTWELI 449
VD W+ G IL+ LVGY PF + Y+ ++ G Y F W+ +
Sbjct: 193 PVDLWACGVILYILLVGYPPFWDEDQHRLYQQIK------------AGAYDFPSPEWDTV 240
Query: 450 TRLIADPINRLKSFEHVKRM 469
T D IN++ + KR+
Sbjct: 241 TPEAKDLINKMLTINPSKRI 260
>Hs20127418 [T] KOG0033 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 664
Score = 82.8 bits (203), Expect = 1e-15
Identities = 69/260 (26%), Positives = 106/260 (40%), Gaps = 57/260 (21%)
Query: 215 DHVLTERD--ILTTTRSEWLVKLLYAFQDPQSLYLAMEFVPGGDFRTLLLNTKFLQAPHA 272
DH ER+ I + +V+L + + YL + V GG+ ++ ++ A
Sbjct: 54 DHQKLEREARICRLLKHSNIVRLHDSISEEGFHYLVFDLVTGGELFEDIVAREYYSEADA 113
Query: 273 RFYISEMFCAVNALHQLGYTHRDLKPENFLIDSK---GHIKLTDFGLASGTVSMERIESM 329
I ++ AV HQ+G HRDLKPEN L+ SK +KL DFGLA
Sbjct: 114 SHCIQQILEAVLHCHQMGVVHRDLKPENLLLASKCKGAAVKLADFGLA------------ 161
Query: 330 KIRLQEVKNLEFPEFRERSMDDRRRMYNKLREEEVRYAHSTVGSPDYMALEVLEAKNYDF 389
I +Q + F G+P Y++ EVL + Y
Sbjct: 162 -IEVQGDQQAWF---------------------------GFAGTPGYLSPEVLRKEAYGK 193
Query: 390 TVDYWSLGCILFESLVGYTPFSGNSTNETYENLRNWKHVLQRPKCDNGRYAFSDRTWELI 449
VD W+ G IL+ LVGY PF ++ Y+ ++ G Y F W+ +
Sbjct: 194 PVDIWACGVILYILLVGYPPFWDEDQHKLYQQIK------------AGAYDFPSPEWDTV 241
Query: 450 TRLIADPINRLKSFEHVKRM 469
T + IN++ + KR+
Sbjct: 242 TPEAKNLINQMLTINPAKRI 261
>CE26649 [D] KOG0575 Polo-like serine/threonine protein kinase
Length = 648
Score = 82.8 bits (203), Expect = 1e-15
Identities = 53/193 (27%), Positives = 82/193 (42%), Gaps = 41/193 (21%)
Query: 232 LVKLLYAFQDPQSLYLAMEFVPGGDFRTLLLNTKFLQAPHARFYISEMFCAVNALHQLGY 291
+VKL F+D ++Y+ +E L K + P AR++ ++ V LH L
Sbjct: 98 IVKLFNFFEDNLNVYITLELCARRSLMELHKRRKAVTEPEARYFTHQIVDGVLYLHDLNI 157
Query: 292 THRDLKPENFLIDSKGHIKLTDFGLASGTVSMERIESMKIRLQEVKNLEFPEFRERSMDD 351
HRD+K N ++ +K+ DFGLA+ ER +++
Sbjct: 158 IHRDMKLGNLFLNDDLVVKIGDFGLATTVNGDERKKTL---------------------- 195
Query: 352 RRRMYNKLREEEVRYAHSTVGSPDYMALEVLEAKNYDFTVDYWSLGCILFESLVGYTPFS 411
G+P+Y+A EVL + F VD W++GCIL+ L G PF
Sbjct: 196 -------------------CGTPNYIAPEVLNKAGHSFEVDIWAVGCILYILLFGQPPFE 236
Query: 412 GNSTNETYENLRN 424
S ETY +R+
Sbjct: 237 SKSLEETYSRIRH 249
>At5g01820 [T] KOG0583 Serine/threonine protein kinase
Length = 442
Score = 82.8 bits (203), Expect = 1e-15
Identities = 58/208 (27%), Positives = 91/208 (42%), Gaps = 40/208 (19%)
Query: 216 HVLTERDILTTTRSEWLVKLLYAFQDPQSLYLAMEFVPGGDFRTLLLNTKFLQAPHARFY 275
++ E I+ R +V+L ++ MEF GG+ + +F + +R Y
Sbjct: 66 NIQREIAIMHRLRHPSIVRLFEVLATKSKIFFVMEFAKGGELFAKVSKGRFCE-DLSRRY 124
Query: 276 ISEMFCAVNALHQLGYTHRDLKPENFLIDSKGHIKLTDFGLASGTVSMERIESMKIRLQE 335
++ AV H G HRDLKPEN L+D K +K++DFGL++ T
Sbjct: 125 FQQLISAVGYCHSRGIFHRDLKPENLLLDEKLDLKISDFGLSALT--------------- 169
Query: 336 VKNLEFPEFRERSMDDRRRMYNKLREEEVRYAHSTVGSPDYMALEVLEAKNYD-FTVDYW 394
+++R + + H+ G+P Y+A EVL K YD +D W
Sbjct: 170 ---------------------DQIRPDGL--LHTLCGTPAYVAPEVLAKKGYDGAKIDIW 206
Query: 395 SLGCILFESLVGYTPFSGNSTNETYENL 422
S G ILF GY PF+ ++ Y +
Sbjct: 207 SCGIILFVLNAGYLPFNDHNLMVMYRKI 234
>At1g48260 [T] KOG0583 Serine/threonine protein kinase
Length = 432
Score = 82.8 bits (203), Expect = 1e-15
Identities = 56/180 (31%), Positives = 80/180 (44%), Gaps = 39/180 (21%)
Query: 232 LVKLLYAFQDPQSLYLAMEFVPGGDFRTLLLNTKFLQAPHARFYISEMFCAVNALHQLGY 291
+V+L +Y+ +E V GGD +++ L R ++ V+ H G
Sbjct: 71 IVRLHEVLASKTKIYMVLECVTGGDLFDRIVSKGKLSETQGRKMFQQLIDGVSYCHNKGV 130
Query: 292 THRDLKPENFLIDSKGHIKLTDFGLASGTVSMERIESMKIRLQEVKNLEFPEFRERSMDD 351
HRDLK EN L+D+KGHIK+TDFGL++ + +RE +
Sbjct: 131 FHRDLKLENVLLDAKGHIKITDFGLSALS---------------------QHYREDGL-- 167
Query: 352 RRRMYNKLREEEVRYAHSTVGSPDYMALEVLEAKNYDFTV-DYWSLGCILFESLVGYTPF 410
H+T GSP+Y+A EVL + YD D WS G IL+ L G PF
Sbjct: 168 ---------------LHTTCGSPNYVAPEVLANEGYDGAASDIWSCGVILYVILTGCLPF 212
Database: KOG eukaryal database 04/03
Posted date: Apr 14, 2003 1:07 PM
Number of letters in database: 30,389,216
Number of sequences in database: 60,738
Lambda K H
0.320 0.137 0.404
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 34,438,263
Number of Sequences: 60738
Number of extensions: 1503310
Number of successful extensions: 8403
Number of sequences better than 1.0e-05: 630
Number of HSP's better than 0.0 without gapping: 364
Number of HSP's successfully gapped in prelim test: 266
Number of HSP's that attempted gapping in prelim test: 6947
Number of HSP's gapped (non-prelim): 1262
length of query: 567
length of database: 30,389,216
effective HSP length: 112
effective length of query: 455
effective length of database: 23,586,560
effective search space: 10731884800
effective search space used: 10731884800
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)