ORF STATUS Function Best COG Functional category Pathways and functional systems
r_klactIV3756 good I KOG3240 Lipid transport and metabolism Phosphatidylinositol synthase
Only best alignment is shown:
BLASTP 2.2.3 [May-13-2002]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= r_klactIV3756 1269125 1269799 225
(225 letters)
Database: KOG eukaryal database 04/03
60,738 sequences; 30,389,216 total letters
Searching..................................................done
Color Key for Alignment Scores: 
Score E
Sequences producing significant alignments: (bits) Value
YPR113w [I] KOG3240 Phosphatidylinositol synthase 256 2e-68
SPAC1D4.08 [I] KOG3240 Phosphatidylinositol synthase 184 1e-46
CE21973 [I] KOG3240 Phosphatidylinositol synthase 144 1e-34
Hs5453906 [I] KOG3240 Phosphatidylinositol synthase 141 6e-34
Hs22027475 [I] KOG3240 Phosphatidylinositol synthase 132 3e-31
At4g38570 [I] KOG3240 Phosphatidylinositol synthase 124 8e-29
At1g68000 [I] KOG3240 Phosphatidylinositol synthase 124 8e-29
7293106 [I] KOG3240 Phosphatidylinositol synthase 109 3e-24
ECU01g1000 [I] KOG3240 Phosphatidylinositol synthase 77 2e-14
>YPR113w [I] KOG3240 Phosphatidylinositol synthase
Length = 220
Score = 256 bits (654), Expect = 2e-68
Identities = 130/217 (59%), Positives = 153/217 (69%), Gaps = 11/217 (5%)
Query: 4 VTARDVLWYIPNQIGYVRVVTMCLSLVLMAKHPLWTMVVYGVSCLLDALDGTMARKYGQI 63
VTA VLWYIPN+IGYVRV+T LS +M HP +Y SCLLDALDGTMARKY Q+
Sbjct: 10 VTAEHVLWYIPNKIGYVRVITAALSFFVMKNHPTAFTWLYSTSCLLDALDGTMARKYNQV 69
Query: 64 SSFGAVLDMVTDRSTTTALICFLCVAYPVWSPVFQLLVALDISSHYIHMYATLSTGSQSH 123
SS GAVLDMVTDRS+T L+CFLCV YP W FQL++ LDI+SHY+HMYA+LS G SH
Sbjct: 70 SSLGAVLDMVTDRSSTAGLMCFLCVQYPQWCVFFQLMLGLDITSHYMHMYASLSAGKTSH 129
Query: 124 KAI-EKEQWLLNLYYTRRKVLFTICALNEMFYMGLYINAFPQFKSYYFPLLGSTHIGAII 182
K++ E E LL+LYYTRR VLFTICA NE+FY GLY+ F S G
Sbjct: 130 KSVGEGESRLLHLYYTRRDVLFTICAFNELFYAGLYLQLFS----------NSATFGKWT 179
Query: 183 ALVCLPGYIFKQIANVVQLNRAALMLANKDAAEATER 219
++ PGY+FKQ ANVVQL RAAL+LA+ DA A E+
Sbjct: 180 TIISFPGYVFKQTANVVQLKRAALILADNDAKNANEK 216
>SPAC1D4.08 [I] KOG3240 Phosphatidylinositol synthase
Length = 251
Score = 184 bits (466), Expect = 1e-46
Identities = 103/220 (46%), Positives = 140/220 (62%), Gaps = 15/220 (6%)
Query: 17 IGYVRVVTMCLSLVLMAKHPLWTMVVYGVSCLLDALDGTMARKYGQISSFGAVLDMVTDR 76
+G+ RV + +SL M+ HP + +VY S LLDA DG ARK Q ++FGA+LDMVTDR
Sbjct: 33 LGFTRVFLVLISLYFMSWHPNYCTIVYLYSSLLDAFDGWAARKLHQATNFGAILDMVTDR 92
Query: 77 STTTALICFLCVAYPVWSPVFQLLVALDISSHYIHMYATLSTGSQSHKAI-EKEQWLLNL 135
T+ L+CFLC AYP ++ +FQLLV+LD++SHY+HMY+TL G+ SHK + +K W+L L
Sbjct: 93 CATSCLLCFLCAAYPKYAIIFQLLVSLDLASHYMHMYSTLHQGASSHKTVTKKHNWMLRL 152
Query: 136 YYTRRKVLFTICALNEMFYMGLYINAFPQF---KSYYFPL---LGST-----HIGAIIAL 184
YY KVLF CA NEMF++ LY+ +F K Y P+ + ST ++A+
Sbjct: 153 YYGNNKVLFIFCAANEMFFVALYLLSFTPRTPPKLGYLPVPSFIYSTGELPLSYPTLLAV 212
Query: 185 VCLPGYIFKQIANVVQLNRAALMLANKDAAEATERRSAKK 224
+C P + KQI NVVQL AA L D +RR+AKK
Sbjct: 213 LCGPICLAKQIINVVQLVNAANALVKMD---VEQRRAAKK 249
>CE21973 [I] KOG3240 Phosphatidylinositol synthase
Length = 220
Score = 144 bits (362), Expect = 1e-34
Identities = 86/211 (40%), Positives = 116/211 (54%), Gaps = 7/211 (3%)
Query: 2 SAVTARDVLWYIPNQIGYVRVVTMCLSLVLMAKHPLWTMVVYGVSCLLDALDGTMARKYG 61
+A +V + PN IGY R+V L++ M+ P M Y +S LDA DG AR Y
Sbjct: 5 AAENNNNVWLFYPNLIGYGRIVLAILAMYYMSSAPWCAMFCYALSAGLDAFDGWAARTYN 64
Query: 62 QISSFGAVLDMVTDRSTTTALICFLCVAYPVWSPVFQLLVALDISSHYIHMYATLSTGSQ 121
Q S FGA+LD +TDR AL+ LC YP + QL +DI+SH++H++AT +G+
Sbjct: 65 QSSRFGAMLDQLTDRCALLALVMALCKFYPDHLFLLQLSAVIDIASHWLHLHATDLSGAT 124
Query: 122 SHKAIEKEQWLLNLYYTRRKVLFTICALNEMFYMGLYINAFPQFKSYYFPLLGSTHIGAI 181
SHK + WLLNLYYT R L +C NE FY+ LYI AF + PL+ + H +I
Sbjct: 125 SHK--QSSNWLLNLYYTDRLFLGFMCGGNEAFYILLYIRAF-----WAGPLIFNFHFMSI 177
Query: 182 IALVCLPGYIFKQIANVVQLNRAALMLANKD 212
L+ P K +VV L AA M+ D
Sbjct: 178 FPLIAFPIAFVKSAISVVHLYTAAEMVVAHD 208
>Hs5453906 [I] KOG3240 Phosphatidylinositol synthase
Length = 213
Score = 141 bits (356), Expect = 6e-34
Identities = 81/214 (37%), Positives = 127/214 (58%), Gaps = 6/214 (2%)
Query: 8 DVLWYIPNQIGYVRVVTMCLSLVLMAKHPLWTMVVYGVSCLLDALDGTMARKYGQISSFG 67
++ ++PN IGY R+V +S M PL Y +S LLDA DG AR Q + FG
Sbjct: 5 NIFLFVPNLIGYARIVFAIISFYFMPCCPLTASSFYLLSGLLDAFDGHAARALNQGTRFG 64
Query: 68 AVLDMVTDRSTTTALICFLCVAYPVWSPVFQLLVALDISSHYIHMYATLSTGSQSHKAIE 127
A+LDM+TDR +T L+ L + YP + FQ+ ++LD++SH++H+++++ GS+SHK I+
Sbjct: 65 AMLDMLTDRCSTMCLLVNLALLYPGATLFFQISMSLDVASHWLHLHSSVVRGSESHKMID 124
Query: 128 -KEQWLLNLYYTRRKVLFTICALNEMFYMGLYINAFPQFKSYYFPLLGSTHIGAIIALVC 186
+L +YYT R LFT+CA NE+FY LY+ F + PL+GS + + V
Sbjct: 125 LSGNPVLRIYYTSRPALFTLCAGNELFYCLLYLFHFSE-----GPLVGSVGLFRMGLWVT 179
Query: 187 LPGYIFKQIANVVQLNRAALMLANKDAAEATERR 220
P + K + +V+ L AA +A DAA+ +++
Sbjct: 180 APIALLKSLISVIHLITAARNMAALDAADRAKKK 213
>Hs22027475 [I] KOG3240 Phosphatidylinositol synthase
Length = 244
Score = 132 bits (333), Expect = 3e-31
Identities = 78/204 (38%), Positives = 120/204 (58%), Gaps = 6/204 (2%)
Query: 18 GYVRVVTMCLSLVLMAKHPLWTMVVYGVSCLLDALDGTMARKYGQISSFGAVLDMVTDRS 77
GY R+V +S M PL Y +S LLDA DG AR Q + FGA+LDM+TDR
Sbjct: 46 GYARIVFAIISFYFMPCCPLTASSFYLLSGLLDAFDGHAARALNQGTRFGAMLDMLTDRC 105
Query: 78 TTTALICFLCVAYPVWSPVFQLLVALDISSHYIHMYATLSTGSQSHKAIE-KEQWLLNLY 136
+T L+ L + YP + FQ+ ++LD++SH++H+++++ GS+SHK I+ +L +Y
Sbjct: 106 STMCLLVNLALLYPGATLFFQISMSLDVASHWLHLHSSVVRGSESHKMIDLSGNPVLRIY 165
Query: 137 YTRRKVLFTICALNEMFYMGLYINAFPQFKSYYFPLLGSTHIGAIIALVCLPGYIFKQIA 196
YT R LFT+CA NE+FY LY+ F + PL+GS + + V P + K +
Sbjct: 166 YTSRPALFTLCAGNELFYCLLYLFHFSE-----GPLVGSVGLFRMGLWVTAPIALLKSLI 220
Query: 197 NVVQLNRAALMLANKDAAEATERR 220
+V+ L AA +A DAA+ +++
Sbjct: 221 SVIHLITAARNMAALDAADRAKKK 244
>At4g38570 [I] KOG3240 Phosphatidylinositol synthase
Length = 225
Score = 124 bits (312), Expect = 8e-29
Identities = 78/201 (38%), Positives = 114/201 (55%), Gaps = 5/201 (2%)
Query: 9 VLWYIPNQIGYVRVVTMCLSLVLMAKHPLWTMVVYGVSCLLDALDGTMARKYGQISSFGA 68
V YIPN +GY+RV+ C++ + + ++Y S DA+DG ARK+ Q+S+FGA
Sbjct: 11 VYLYIPNIVGYMRVLLNCIAFSVCFSNKTLFSLLYFFSFCCDAVDGWCARKFNQVSTFGA 70
Query: 69 VLDMVTDRSTTTALICFLCVAYPVWSPVFQLLVALDISSHYIHMYATLSTGSQSHKAI-E 127
VLDMVTDR +T L+ L Y S VF L+ALDI+SH++ MY+T +G SHK + +
Sbjct: 71 VLDMVTDRVSTACLLVILSQIYRP-SLVFLSLLALDIASHWLQMYSTFLSGKTSHKDVKD 129
Query: 128 KEQWLLNLYYTRRKVLFTICALNEMFYMGLYINAFPQFKSYYFPLLGS-THIGAIIALVC 186
WL LYY R + C E+ Y+ L + A Q ++ ++ S I + L+
Sbjct: 130 STSWLFRLYYGNRMFMGYCCVSCEVLYIILLLIATNQTENLMNVVVKSLMQISPLSLLLA 189
Query: 187 LP--GYIFKQIANVVQLNRAA 205
L G+ KQI NV+Q+ AA
Sbjct: 190 LSIFGWSIKQIINVIQMKTAA 210
>At1g68000 [I] KOG3240 Phosphatidylinositol synthase
Length = 227
Score = 124 bits (312), Expect = 8e-29
Identities = 80/202 (39%), Positives = 118/202 (57%), Gaps = 7/202 (3%)
Query: 9 VLWYIPNQIGYVRVVTMCLSL-VLMAKHPLWTMVVYGVSCLLDALDGTMARKYGQISSFG 67
V YIPN +GY+RV+ C++ V + PL++ V+Y S DA+DG +AR++ Q+S+FG
Sbjct: 14 VYLYIPNIVGYMRVLLNCVAFAVCFSNKPLFS-VLYFFSFCCDAVDGWVARRFNQVSTFG 72
Query: 68 AVLDMVTDRSTTTALICFLCVAYPVWSPVFQLLVALDISSHYIHMYATLSTGSQSHKAI- 126
AVLDMVTDR +T L+ L Y S VF L+ALDI+SH++ MY+T G SHK +
Sbjct: 73 AVLDMVTDRVSTACLLVILSQIYRP-SLVFLSLLALDIASHWLQMYSTFLAGKSSHKDVK 131
Query: 127 EKEQWLLNLYYTRRKVLFTICALNEMFYMGLYINAFPQFKSYYFPLLGS-THIGAIIALV 185
+ WL LYY R + C E+ Y+ L + A Q ++ ++ + T I + L+
Sbjct: 132 DSTSWLFRLYYGNRIFMCYCCVSCEVLYIILLLIAKNQSENLLNVVVATLTQISPLSFLL 191
Query: 186 CLP--GYIFKQIANVVQLNRAA 205
L G+ KQ NV+Q+ AA
Sbjct: 192 ALTLFGWSMKQTINVIQMKTAA 213
>7293106 [I] KOG3240 Phosphatidylinositol synthase
Length = 193
Score = 109 bits (273), Expect = 3e-24
Identities = 64/178 (35%), Positives = 100/178 (55%), Gaps = 8/178 (4%)
Query: 43 YGVSCLLDALDGTMARKYGQISSFGAVLDMVTDRSTTTALICFLCVAYPVWSPVFQLLVA 102
Y S LLDA+DG AR + Q + FGA+LD +TDR TT L+ L YP + FQL +A
Sbjct: 12 YVTSALLDAVDGQAARAFNQSTRFGAMLDQLTDRCGTTGLLVTLAYFYPRYMFWFQLSIA 71
Query: 103 LDISSHYIHMYATLSTGSQSHKAIEKEQWLLNLYYTRRKVLFTICALNEMFYMGLYINAF 162
+D++ H++ M ++ G SHK + +++ LYY ++ +L +C +NE+FY+ LY+ F
Sbjct: 72 IDVACHWLFMQTSVVVGRSSHKV--NDNFIMRLYY-QKDILTFMCCVNELFYVCLYLLHF 128
Query: 163 PQFKSYYFPLLGSTHIGAIIALVCLPGYIFKQIANVVQLNRAALMLANKDAAEATERR 220
Y PL+ + I+A + P + K + +V+ A + LA D E ERR
Sbjct: 129 T-----YGPLIFGASLFKILAFLTGPFAVLKALISVMHAYVAGIDLAAVDVRERQERR 181
>ECU01g1000 [I] KOG3240 Phosphatidylinositol synthase
Length = 196
Score = 77.0 bits (188), Expect = 2e-14
Identities = 47/150 (31%), Positives = 78/150 (51%), Gaps = 7/150 (4%)
Query: 9 VLWYIPNQIGYVRVVTMCLSLVLMAKHPLWTMVVYGVSCLLDALDGTMARKYGQISSFGA 68
V++ IPN +GY+R+ + LS + +V+YG+S LD DG AR Q S G+
Sbjct: 5 VIFNIPNSLGYLRICLLILSTFVSGST---FVVLYGLSSSLDFFDGHFARMLNQCSLLGS 61
Query: 69 VLDMVTDRSTTTALICFLCVAYPVWSPVFQLLVALDISSHYIHMYATLSTGSQSHKAIEK 128
LDM+TD ++ ++ + + + + D+ SH+ + + G + HK +
Sbjct: 62 CLDMITDLTSRVVILLRIVQRRSECLQLLTIYMVFDLISHFTYFHMAALVG-RHHKRTDN 120
Query: 129 EQWLLNLYYTRRKVLFTICALNEMFYMGLY 158
L +YY +R VL IC L+EMF+M +Y
Sbjct: 121 R--FLRIYYDKR-VLGPICLLSEMFFMYMY 147
Database: KOG eukaryal database 04/03
Posted date: Apr 14, 2003 1:07 PM
Number of letters in database: 30,389,216
Number of sequences in database: 60,738
Lambda K H
0.327 0.137 0.421
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 12,021,893
Number of Sequences: 60738
Number of extensions: 444810
Number of successful extensions: 1227
Number of sequences better than 1.0e-05: 9
Number of HSP's better than 0.0 without gapping: 8
Number of HSP's successfully gapped in prelim test: 1
Number of HSP's that attempted gapping in prelim test: 1204
Number of HSP's gapped (non-prelim): 9
length of query: 225
length of database: 30,389,216
effective HSP length: 102
effective length of query: 123
effective length of database: 24,193,940
effective search space: 2975854620
effective search space used: 2975854620
T: 11
A: 40
X1: 15 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 40 (21.8 bits)