ORF STATUS Function Best COG Functional category Pathways and functional systems
r_klactIV3760 good TR KOG4561 General function prediction only Uncharacterized conserved protein, contains TBC domain
r_klactIV3760 good TR KOG4561 Signal transduction mechanisms Uncharacterized conserved protein, contains TBC domain
Only best alignment is shown:
BLASTP 2.2.3 [May-13-2002]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= r_klactIV3760 1270160 1271143 328
(328 letters)
Database: KOG eukaryal database 04/03
60,738 sequences; 30,389,216 total letters
Searching..................................................done
Color Key for Alignment Scores: 
Score E
Sequences producing significant alignments: (bits) Value
YPR114w [TR] KOG4561 Uncharacterized conserved protein contains ... 290 3e-78
SPAC17A2.02c [TR] KOG4561 Uncharacterized conserved protein cont... 94 3e-19
YJR116w [TR] KOG4561 Uncharacterized conserved protein contains ... 77 3e-14
>YPR114w [TR] KOG4561 Uncharacterized conserved protein contains TBC domain
Length = 315
Score = 290 bits (741), Expect = 3e-78
Identities = 144/312 (46%), Positives = 202/312 (64%), Gaps = 19/312 (6%)
Query: 25 VMSLPPHPHLTEYVIPYLESNGWITSNVILSNLHTVLYIAVGYHALFLLSQRVLFPPLAS 84
++SLP VIP+L + I S ILSNLH++ Y+A+ YH FL + +LFP L
Sbjct: 4 LLSLPQPELFKTTVIPFLANRNIIKSEAILSNLHSIFYVAIFYHIWFLFGKWILFPHLVK 63
Query: 85 YRLSWDPE--TTKDQRKSKEKQ-------HADLVNQSAVRLVSWIQSLIVLYLSFEAIA- 134
++L +D + KD++ + E+Q + L+NQS+V L+S +QS++VLY S + +
Sbjct: 64 WKLDYDQKHNVKKDEKTTSERQAQHYKKKYTSLINQSSVHLISLLQSIVVLYYSLKFLLD 123
Query: 135 -YNNEKPDLNSHDRIFGMDPYNVKVCVFAIGYFLWDIYISLVYSTLPFVLHGLISTVVYA 193
+ +P SH R+F + +C+FAIGYF+WDIYIS +YST PFV+HG+ISTVV+
Sbjct: 124 PKASAEPYQTSHSRVFTENRDTQVICIFAIGYFVWDIYISTMYSTFPFVVHGIISTVVFC 183
Query: 194 IGLKPYINYYAGIFLMFELSNPFLNIRWFGIKYLPQLTKDCQTVMAKXXXXXXXXXXXXX 253
IGLKPYI YYA +FLMFELSNP LN RWFGIK+LPQ +K C ++
Sbjct: 184 IGLKPYIQYYAPVFLMFELSNPSLNFRWFGIKFLPQKSKFCSLLL--------LLNNLTL 235
Query: 254 XXXFFLARICWGFYQFYQLCTDFYNIRNDPSFLPLETAIIVTGNLILDVLNLFWLSTMLS 313
FF ARI WG++Q +LC DFY +RN+P FL +T +I+ GN +LD+LN+ W STM+S
Sbjct: 236 MVVFFAARIAWGWFQIGKLCYDFYQVRNEPGFLVFDTIVILAGNFVLDILNVIWFSTMVS 295
Query: 314 VAVRIIKKGGKV 325
VA +++KKG V
Sbjct: 296 VAAKVLKKGESV 307
>SPAC17A2.02c [TR] KOG4561 Uncharacterized conserved protein contains TBC domain
Length = 290
Score = 94.0 bits (232), Expect = 3e-19
Identities = 80/288 (27%), Positives = 129/288 (44%), Gaps = 43/288 (14%)
Query: 34 LTEYVIPYLESNGWITSNVILSNLHTVLYIAVGYHALFLLSQRVLFPPLASYRLSWDPET 93
L E+V P+ + G + ++H +L A+ Y + +LS P+ S LS
Sbjct: 20 LEEFVKPFCDRFGLTK---LPRHMHVILLSALFYQIINILS------PVISRHLS----- 65
Query: 94 TKDQRKSKEKQHADLVNQSAVRLVSWIQSLIVLYLSFEAIAYNNEKPDLNSHDRIFGMDP 153
T + SK+ + +N A +VS +QS++++ L + + N PD ++FG
Sbjct: 66 THYAKLSKKTR----LNWDA-HVVSSVQSIVLICLGYTCLKEVNAFPD-----KLFGYSV 115
Query: 154 YNVKVCVFAIGYFLWDIYISLVY---STLPFVLHGLISTVVYAIGLKPYINYYAGIFLMF 210
+ GYF+WD+YI++ Y + + FV+H + + V +PY+ YY +L +
Sbjct: 116 VAGDIYALTAGYFVWDLYITVRYVHITGIGFVIHAIAALFVITFSYRPYLMYYGPTYLSW 175
Query: 211 ELSNPFLNIRWFGIKYLPQLTKDCQTVMAKXXXXXXXXXXXXXXXXFFLARICWGFYQFY 270
ELS PFLNI +F L K +T F RI WG++ Y
Sbjct: 176 ELSTPFLNIHYF-------LDKTNRT-----GSKFQMINGFILIVTFICVRIAWGWFSAY 223
Query: 271 QLCTDFYN-IRNDPSFLPLETAIIVTGNLILDVLNLFWLSTMLSVAVR 317
+ N I P L L + N+ L+ LNLFW+S M+ R
Sbjct: 224 STAIEILNHINVAPWALSL---FYLAANMSLNCLNLFWVSKMIDAIRR 268
>YJR116w [TR] KOG4561 Uncharacterized conserved protein contains TBC domain
Length = 279
Score = 77.4 bits (189), Expect = 3e-14
Identities = 68/276 (24%), Positives = 120/276 (42%), Gaps = 33/276 (11%)
Query: 49 TSNVILSNLHTVLYIAVGYHALFLLSQRVLFPPLASYRLSWDPETTKDQRKSKEKQHADL 108
+SN+IL++LH +++ V Y F V+ P L T +D +
Sbjct: 25 SSNLILAHLHEIIFSFVFYQLAF----SVVAPFLNKVVFRKHYTTIRDPLLKID------ 74
Query: 109 VNQSAVRLVSWIQSLIVLYLSFEAIAYNNEKPDLNSHDRIFGMDPYNVKVCVFAIGYFLW 168
N V ++ + S VL + + N + D Y+ V + GYF+W
Sbjct: 75 FNVHTVSMIQAVVSNTVLLPTLTTPMHYNV---------VTYTDSYSSMVSSLSAGYFIW 125
Query: 169 DIYISLVYSTL---PFVLHGLISTVVYAIGLKPYINYYAGIFLMFELSNPFLNIRWFGIK 225
D+ + + Y L F H + S V + L+P+ + G FL++E S PF+NI WF I
Sbjct: 126 DLTMCVRYFKLYGLEFTGHAIGSVYVMLLSLRPFCQPWIGRFLIYEASTPFVNINWF-IM 184
Query: 226 YLPQLTKDCQTVMAKXXXXXXXXXXXXXXXXFFLARICWGFYQFYQLCTDFYNIRNDPSF 285
+K+ + FF+ RICWG L + +R++
Sbjct: 185 QCNAKSKNSIPLW------FNVVNGLLLMTVFFVVRICWGSIASALLFRQMWKVRDE--- 235
Query: 286 LPLETAI-IVTGNLILDVLNLFWLSTMLSVAVRIIK 320
LP +A+ +++ N+ +++LN+ W M+ +A ++ K
Sbjct: 236 LPKFSAVTMMSLNIFMNLLNVLWFKKMIRIAKKLAK 271
Database: KOG eukaryal database 04/03
Posted date: Apr 14, 2003 1:07 PM
Number of letters in database: 30,389,216
Number of sequences in database: 60,738
Lambda K H
0.326 0.141 0.439
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 18,635,071
Number of Sequences: 60738
Number of extensions: 733704
Number of successful extensions: 2324
Number of sequences better than 1.0e-05: 3
Number of HSP's better than 0.0 without gapping: 1
Number of HSP's successfully gapped in prelim test: 2
Number of HSP's that attempted gapping in prelim test: 2313
Number of HSP's gapped (non-prelim): 5
length of query: 328
length of database: 30,389,216
effective HSP length: 107
effective length of query: 221
effective length of database: 23,890,250
effective search space: 5279745250
effective search space used: 5279745250
T: 11
A: 40
X1: 15 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 40 (21.7 bits)