ORF STATUS Function Best COG Functional category Pathways and functional systems
r_klactIV3882 good D KOG0653 Cell cycle control, cell division, chromosome partitioning Cyclin B and related kinase-activating proteins
Only best alignment is shown:
BLASTP 2.2.3 [May-13-2002]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= r_klactIV3882 1313760 1315376 539
(539 letters)
Database: KOG eukaryal database 04/03
60,738 sequences; 30,389,216 total letters
Searching..................................................done
Color Key for Alignment Scores: 
Score E
Sequences producing significant alignments: (bits) Value
YPR119w [D] KOG0653 Cyclin B and related kinase-activating proteins 543 e-154
YGR108w [D] KOG0653 Cyclin B and related kinase-activating proteins 488 e-137
SPBC582.03 [D] KOG0653 Cyclin B and related kinase-activating pr... 311 1e-84
SPAPB2B4.03 [D] KOG0653 Cyclin B and related kinase-activating p... 243 5e-64
YDL155w [D] KOG0653 Cyclin B and related kinase-activating proteins 234 2e-61
YGR109c [D] KOG0653 Cyclin B and related kinase-activating proteins 228 1e-59
YPR120c [D] KOG0653 Cyclin B and related kinase-activating proteins 218 1e-56
Hs4757930 [D] KOG0653 Cyclin B and related kinase-activating pro... 217 4e-56
YLR210w [D] KOG0653 Cyclin B and related kinase-activating proteins 212 1e-54
Hs14327896 [D] KOG0653 Cyclin B and related kinase-activating pr... 186 6e-47
ECU08g0260 [D] KOG0653 Cyclin B and related kinase-activating pr... 172 1e-42
At4g35620 [D] KOG0653 Cyclin B and related kinase-activating pro... 152 2e-36
Hs4502611 [D] KOG0654 G2/Mitotic-specific cyclin A 147 4e-35
7291478 [D] KOG0653 Cyclin B and related kinase-activating proteins 147 5e-35
SPBC16E9.17c [D] KOG0653 Cyclin B and related kinase-activating ... 145 1e-34
At2g17620 [D] KOG0653 Cyclin B and related kinase-activating pro... 145 1e-34
At5g06150 [D] KOG0653 Cyclin B and related kinase-activating pro... 142 1e-33
At5g43080 [D] KOG0654 G2/Mitotic-specific cyclin A 142 1e-33
SPCC4E9.02 [D] KOG0653 Cyclin B and related kinase-activating pr... 141 3e-33
At1g80370 [D] KOG0654 G2/Mitotic-specific cyclin A 140 4e-33
At1g20610 [D] KOG0653 Cyclin B and related kinase-activating pro... 140 6e-33
At1g47210 [D] KOG0654 G2/Mitotic-specific cyclin A 139 8e-33
At2g26760 [D] KOG0653 Cyclin B and related kinase-activating pro... 138 2e-32
At5g11300 [D] KOG0654 G2/Mitotic-specific cyclin A 137 4e-32
At1g77390 [D] KOG0654 G2/Mitotic-specific cyclin A 137 5e-32
At3g11520 [D] KOG0653 Cyclin B and related kinase-activating pro... 136 9e-32
At1g15570 [D] KOG0654 G2/Mitotic-specific cyclin A 134 5e-31
At1g44110 [D] KOG0654 G2/Mitotic-specific cyclin A 133 8e-31
At4g37490 [D] KOG0653 Cyclin B and related kinase-activating pro... 132 1e-30
At1g47220 [D] KOG0654 G2/Mitotic-specific cyclin A 132 1e-30
At5g25380 [D] KOG0654 G2/Mitotic-specific cyclin A 131 2e-30
At1g16330 [D] KOG0653 Cyclin B and related kinase-activating pro... 131 2e-30
At1g47230 [D] KOG0654 G2/Mitotic-specific cyclin A 127 6e-29
Hs14719420_2 [D] KOG0653 Cyclin B and related kinase-activating ... 127 6e-29
Hs4502613 [D] KOG0654 G2/Mitotic-specific cyclin A 124 3e-28
At1g76310 [D] KOG0653 Cyclin B and related kinase-activating pro... 124 5e-28
7294661 [D] KOG0654 G2/Mitotic-specific cyclin A 123 6e-28
CE27776 [D] KOG0653 Cyclin B and related kinase-activating proteins 121 3e-27
CE13315 [D] KOG0653 Cyclin B and related kinase-activating proteins 121 3e-27
CE23835 [D] KOG0653 Cyclin B and related kinase-activating proteins 107 6e-23
CE28122 [D] KOG0653 Cyclin B and related kinase-activating proteins 105 2e-22
Hs16306525_2 [D] KOG0653 Cyclin B and related kinase-activating ... 102 1e-21
CE06570 [D] KOG0653 Cyclin B and related kinase-activating proteins 100 9e-21
CE03820 [D] KOG0654 G2/Mitotic-specific cyclin A 98 4e-20
Hs22062947 [D] KOG0653 Cyclin B and related kinase-activating pr... 92 2e-18
7298245 [D] KOG0655 G1/S-specific cyclin E 91 3e-18
Hs17318567 [D] KOG0655 G1/S-specific cyclin E 91 6e-18
Hs17318565 [D] KOG0655 G1/S-specific cyclin E 91 6e-18
Hs22048740 [D] KOG0655 G1/S-specific cyclin E 88 4e-17
Hs17318561 [D] KOG0655 G1/S-specific cyclin E 86 2e-16
Hs17318559 [D] KOG0655 G1/S-specific cyclin E 86 2e-16
At1g20590 [D] KOG0653 Cyclin B and related kinase-activating pro... 83 9e-16
CE24832 [D] KOG0655 G1/S-specific cyclin E 79 2e-14
HsM4502615 [D] KOG0656 G1/S-specific cyclin D 78 4e-14
Hs16950655 [D] KOG0656 G1/S-specific cyclin D 77 7e-14
At4g34160 [D] KOG0656 G1/S-specific cyclin D 77 7e-14
At1g34460_1 [D] KOG0653 Cyclin B and related kinase-activating p... 76 1e-13
ECU09g1030 [D] KOG0653 Cyclin B and related kinase-activating pr... 76 1e-13
SPBC19F5.01c [D] KOG0653 Cyclin B and related kinase-activating ... 72 3e-12
Hs4502621 [D] KOG0654 G2/Mitotic-specific cyclin A 69 2e-11
Hs4502617 [D] KOG0656 G1/S-specific cyclin D 68 3e-11
At3g50070 [D] KOG0656 G1/S-specific cyclin D 67 9e-11
Hs5802992 [D] KOG0653 Cyclin B and related kinase-activating pro... 65 3e-10
7293153 [D] KOG0656 G1/S-specific cyclin D 64 4e-10
Hs4502619 [D] KOG0656 G1/S-specific cyclin D 62 3e-09
At5g67260 [D] KOG0656 G1/S-specific cyclin D 60 6e-09
At1g70210 [D] KOG0656 G1/S-specific cyclin D 60 8e-09
7292370 [D] KOG0654 G2/Mitotic-specific cyclin A 57 9e-08
At5g02110 [D] KOG0656 G1/S-specific cyclin D 56 1e-07
Hs13376318 [D] KOG0653 Cyclin B and related kinase-activating pr... 56 2e-07
CE21610 [D] KOG0656 G1/S-specific cyclin D 53 1e-06
Hs4757936 [D] KOG0653 Cyclin B and related kinase-activating pro... 50 7e-06
Hs20541478 [D] KOG0653 Cyclin B and related kinase-activating pr... 50 7e-06
>YPR119w [D] KOG0653 Cyclin B and related kinase-activating proteins
Length = 491
Score = 543 bits (1398), Expect = e-154
Identities = 299/539 (55%), Positives = 367/539 (67%), Gaps = 73/539 (13%)
Query: 9 SLKNLNMLRRPVLNNVTNTT---ESTFGKVLRQAKSRLQNSRT--NNLPQGTANSYSNTK 63
S + L ++R LNNVTNTT + L KS L + + + +PQ T S S +
Sbjct: 16 SSRFLRNVQRLALNNVTNTTFQKSNANNPALTNFKSTLNSVKKEGSRIPQFTRESVSRST 75
Query: 64 PAPLRDDIMVPEDKENYNPLAKIDEREELDSNLVHNHKSLGTQKHVTIDERQEIIGYSHL 123
A +E+ L N + K+ +D
Sbjct: 76 AAQ--------------------EEKRTLKEN------GIQLPKNNLLD----------- 98
Query: 124 DTEKSAPSSSTYSSEHTENDGVHDVNPNVQRSDNEADFKMQTTNAFHENVNXXXXXXXXX 183
D E PSS + + + +G R++ A+ +Q +++ E +
Sbjct: 99 DKENQDPSSQQFGALTSIKEG---------RAELPANISLQESSSAKEIIQHD------- 142
Query: 184 XXXXXXXNECPAVNVGNSLAPMPI---DENANNSASSVELRAKQLQVEDSKKRPISTVVE 240
P VG+S + +E + + S +++R + + + KKRPIST+VE
Sbjct: 143 ----------PLKGVGSSTEVVHNSVENEKLHPARSQLQVRNTESETDSGKKRPISTIVE 192
Query: 241 QTLPKKFKVC-EKGKE-YEWEDLDEEDINDPFMVSEYVTDIFEYLHRLEMMTLPNRHELF 298
Q LPKKFKVC E GKE YEWEDLD ED+NDPFMVSEYV DIFEYLH+LE++TLP + +L+
Sbjct: 193 QELPKKFKVCDENGKEEYEWEDLDAEDVNDPFMVSEYVNDIFEYLHQLEVITLPKKEDLY 252
Query: 299 KHANIQQNRDILVNWMVKIHNKFGLLPETLYLALNIMDRFLCKELVQLEKLQLVGTACLF 358
+H NI QNRDILVNW+VKIHNKFGLLPETLYLA+NIMDRFL KELVQL+KLQLVGT+CLF
Sbjct: 253 QHRNIHQNRDILVNWLVKIHNKFGLLPETLYLAINIMDRFLGKELVQLDKLQLVGTSCLF 312
Query: 359 IASKYEEVYSPSVKHFAYETDGACDEEEIKEGEKFILKTLEFNLNYPNPMNFLRRISKAD 418
IASKYEEVYSPS+KHFA ETDGAC E+EIKEGEKFILKTL+FNLNYPNPMNFLRRISKAD
Sbjct: 313 IASKYEEVYSPSIKHFASETDGACTEDEIKEGEKFILKTLKFNLNYPNPMNFLRRISKAD 372
Query: 419 DYDIQSRTLAKYLLEISIVDFKFIGILPSLCAAASMFLSRKMLGKGQWDGNLIHYSGGYT 478
DYDIQSRTLAK+LLEIS+VDF+FIGILPSLCAAA+MF+SRKMLGKG+WDGNLIHYSGGYT
Sbjct: 373 DYDIQSRTLAKFLLEISLVDFRFIGILPSLCAAAAMFMSRKMLGKGKWDGNLIHYSGGYT 432
Query: 479 KDELAPVCNMVMEYLVQPVVHDELFKKYASRRFMKASVISRQWAKKVMSHNYDIMTLHD 537
K+ELAPVC+M+M+YLV P+VHDE +KY SRRFMKAS+IS QWA KV + YDIMTLH+
Sbjct: 433 KEELAPVCHMIMDYLVSPIVHDEFHRKYQSRRFMKASIISVQWALKVRKNGYDIMTLHE 491
>YGR108w [D] KOG0653 Cyclin B and related kinase-activating proteins
Length = 471
Score = 488 bits (1255), Expect = e-137
Identities = 233/329 (70%), Positives = 281/329 (84%), Gaps = 6/329 (1%)
Query: 215 ASSVELRAKQLQVEDSKKRPISTVVEQTLPKKFKVCEKG------KEYEWEDLDEEDIND 268
++ +E + K ++ + KKRPIST+VEQ KKFK+ E +EYEW+DLDEED +D
Sbjct: 143 STQMEWQKKIMREDSKKKRPISTLVEQDDQKKFKLHELTTEEEVLEEYEWDDLDEEDCDD 202
Query: 269 PFMVSEYVTDIFEYLHRLEMMTLPNRHELFKHANIQQNRDILVNWMVKIHNKFGLLPETL 328
P MVSE V DIF+YLH LE++TLPN+ L+KH NI+QNRDILVNW++KIHNKFGLLPETL
Sbjct: 203 PLMVSEEVNDIFDYLHHLEIITLPNKANLYKHKNIKQNRDILVNWIIKIHNKFGLLPETL 262
Query: 329 YLALNIMDRFLCKELVQLEKLQLVGTACLFIASKYEEVYSPSVKHFAYETDGACDEEEIK 388
YLA+NIMDRFLC+E+VQL +LQLVGT+CLFIASKYEE+YSPS+KHFAYETDGAC E+IK
Sbjct: 263 YLAINIMDRFLCEEVVQLNRLQLVGTSCLFIASKYEEIYSPSIKHFAYETDGACSVEDIK 322
Query: 389 EGEKFILKTLEFNLNYPNPMNFLRRISKADDYDIQSRTLAKYLLEISIVDFKFIGILPSL 448
EGE+FIL+ L+F +++ NPMNFLRRISKADDYDIQSRTLAK+L+EISIVDFKFIGILPSL
Sbjct: 323 EGERFILEKLDFQISFANPMNFLRRISKADDYDIQSRTLAKFLMEISIVDFKFIGILPSL 382
Query: 449 CAAASMFLSRKMLGKGQWDGNLIHYSGGYTKDELAPVCNMVMEYLVQPVVHDELFKKYAS 508
CA+A+MFLSRKMLGKG WDGNLIHYSGGYTK +L PVC ++M+YLV +HDE KKY S
Sbjct: 383 CASAAMFLSRKMLGKGTWDGNLIHYSGGYTKAKLYPVCQLLMDYLVGSTIHDEFLKKYQS 442
Query: 509 RRFMKASVISRQWAKKVMSHNYDIMTLHD 537
RRF+KAS+IS +WA KV + YDIMTLH+
Sbjct: 443 RRFLKASIISIEWALKVRKNGYDIMTLHE 471
>SPBC582.03 [D] KOG0653 Cyclin B and related kinase-activating proteins
Length = 482
Score = 311 bits (798), Expect = 1e-84
Identities = 159/296 (53%), Positives = 212/296 (70%), Gaps = 3/296 (1%)
Query: 231 KKRPISTVVEQTLPKKFK-VCEKGKEYEWEDLDEEDINDPFMVSEYVTDIFEYLHRLEMM 289
KK VV + +PK + E + +W+DLD ED DP MVSEYV DIFEYL+ LE+
Sbjct: 158 KKDVDERVVSKDIPKLHRDSVESPESQDWDDLDAEDWADPLMVSEYVVDIFEYLNELEIE 217
Query: 290 TLPNRHELFKHANIQ-QNRDILVNWMVKIHNKFGLLPETLYLALNIMDRFLCKELVQLEK 348
T+P+ + + + + R IL +W++++H++F LLPETL+LA+NI+DRFL + L K
Sbjct: 218 TMPSPTYMDRQKELAWKMRGILTDWLIEVHSRFRLLPETLFLAVNIIDRFLSLRVCSLNK 277
Query: 349 LQLVGTACLFIASKYEEVYSPSVKHFAYETDGACDEEEIKEGEKFILKTLEFNLNYPNPM 408
LQLVG A LFIASKYEEV PSV++F Y DG DEEEI + E++IL+ LEFNL YPNPM
Sbjct: 278 LQLVGIAALFIASKYEEVMCPSVQNFVYMADGGYDEEEILQAERYILRVLEFNLAYPNPM 337
Query: 409 NFLRRISKADDYDIQSRTLAKYLLEISIVDFKFIGILPSLCAAASMFLSRKMLGKGQWDG 468
NFLRRISKAD YDIQ+RT+AKYL+EI ++D K + PS AA+M+L+R+MLG+G W+
Sbjct: 338 NFLRRISKADFYDIQTRTVAKYLVEIGLLDHKLLPYPPSQQCAAAMYLAREMLGRGPWNR 397
Query: 469 NLIHYSGGYTKDELAPVCNMVMEYLVQPVVHDELFKKYASRRFMKASVISRQWAKK 524
NL+HYS GY + +L V ++ YL +PV H+ FKKYAS++FMKAS+ R W KK
Sbjct: 398 NLVHYS-GYEEYQLISVVKKMINYLQKPVQHEAFFKKYASKKFMKASLFVRDWIKK 452
>SPAPB2B4.03 [D] KOG0653 Cyclin B and related kinase-activating proteins
Length = 411
Score = 243 bits (620), Expect = 5e-64
Identities = 126/300 (42%), Positives = 187/300 (62%), Gaps = 9/300 (3%)
Query: 239 VEQTLPKKFKVCEKGKEYEWEDLDEEDIND--------PFMVSEYVTDIFEYLHRLEMMT 290
VE KK KV K + E L ++ +++ P M EY +IFEY+ +L++
Sbjct: 92 VESKFVKKLKVYSKNADPSVETLQKDRVSNVDDHLSSNPLMAEEYAPEIFEYIRKLDLKC 151
Query: 291 LPNRHELFKHANIQ-QNRDILVNWMVKIHNKFGLLPETLYLALNIMDRFLCKELVQLEKL 349
LPN + + + + R+IL W+V+IH+ F L+PETLYLA+NI+DRFL + L K
Sbjct: 152 LPNPKYMDQQKELTWKMREILNEWLVEIHSNFCLMPETLYLAVNIIDRFLSRRSCSLSKF 211
Query: 350 QLVGTACLFIASKYEEVYSPSVKHFAYETDGACDEEEIKEGEKFILKTLEFNLNYPNPMN 409
QL G L IASKYEEV PS+++F Y TDGA E++ E+++L L F+L+YP+P+N
Sbjct: 212 QLTGITALLIASKYEEVMCPSIQNFVYMTDGAFTVEDVCVAERYMLNVLNFDLSYPSPLN 271
Query: 410 FLRRISKADDYDIQSRTLAKYLLEISIVDFKFIGILPSLCAAASMFLSRKMLGKGQWDGN 469
FLR+IS+A+ YD Q+RTL KYL EI + D + S AAA+M+LSR++L +G W
Sbjct: 272 FLRKISQAEGYDAQTRTLGKYLTEIYLFDHDLLRYPMSKIAAAAMYLSRRLLRRGPWTPK 331
Query: 470 LIHYSGGYTKDELAPVCNMVMEYLVQPVVHDELFKKYASRRFMKASVISRQWAKKVMSHN 529
L+ SGGY + EL + +++ Y +P+ H F+KY+S+RF+KAS+ Q ++ S N
Sbjct: 332 LVESSGGYEEHELKEIAYIMLHYHNKPLEHKAFFQKYSSKRFLKASIFVHQLVRQRYSVN 391
>YDL155w [D] KOG0653 Cyclin B and related kinase-activating proteins
Length = 427
Score = 234 bits (597), Expect = 2e-61
Identities = 115/264 (43%), Positives = 180/264 (67%), Gaps = 3/264 (1%)
Query: 260 DLDEEDINDPFMVSEYVTDIFEYLHRLEMMTLPNRHELFKHANIQQN-RDILVNWMVKIH 318
D +++D+ D MV+E +IFEY+ +LE + PN + + K ++ + R L++W+V++H
Sbjct: 153 DPNDDDVYDVVMVAELSNEIFEYMRKLEDLYKPNPYYMDKQPELRWSFRSTLIDWIVQVH 212
Query: 319 NKFGLLPETLYLALNIMDRFLCKELVQLEKLQLVGTACLFIASKYEEVYSPSVKHFAYET 378
KF LLPETLYL +NI+DR+LCKE+V + K QLVG A LFIA+KYEE+ P++K F Y +
Sbjct: 213 EKFQLLPETLYLCINIIDRYLCKEVVPVNKFQLVGAASLFIAAKYEEINCPTIKDFVYMS 272
Query: 379 DGACDEEEIKEGEKFILKTLEFNLNYPNPMNFLRRISKADDYDIQSRTLAKYLLEISIVD 438
+ ++ + E+ IL LEF L +P PM+FLRRISKADDY+ +RTLAKYLLE +I+D
Sbjct: 273 ENCYSRNDLLDAERTILNGLEFELGWPGPMSFLRRISKADDYEHDTRTLAKYLLESTIMD 332
Query: 439 FKFIGILPSLCAAASMFLSRKMLGKGQWDGNLIHYSGGYTKDELAPVCNMVMEYL-VQPV 497
+ + PS AA + FLS+ +LG+ QW ++YS YT++++ P+ +++E
Sbjct: 333 HRLVSAQPSWLAAGAYFLSKIILGQNQWSLAHVYYS-NYTQEQILPLATIILENCRYASK 391
Query: 498 VHDELFKKYASRRFMKASVISRQW 521
H+ +++KY+SRR++ +S I +W
Sbjct: 392 RHNAIWRKYSSRRYLHSSQIVAKW 415
>YGR109c [D] KOG0653 Cyclin B and related kinase-activating proteins
Length = 380
Score = 228 bits (582), Expect = 1e-59
Identities = 120/280 (42%), Positives = 185/280 (65%), Gaps = 12/280 (4%)
Query: 207 IDENANNSASSVELRAKQLQ-----VEDSKKRPISTVVEQTLPKKFKVCEKGKEYEWEDL 261
+ E +N S++L +LQ +E ++KR +S + T P + K +K K ++W++L
Sbjct: 49 LSEVNSNKIDSLQLPRGKLQRDSTHLEKTRKRQLSN--DSTDPIEPKTVKKIKCHQWKNL 106
Query: 262 DEEDINDPFMVSEYVTDIFEYLHRLEMMTLPNRHELFKHANI----QQNRDILVNWMVKI 317
D +++DPFMV+EY IF +L+ E+ LP + L + R +L++W+V++
Sbjct: 107 DSIEMDDPFMVAEYTDSIFSHLYEKEIQMLPTHNYLMDTQSPYHLKSSMRALLIDWLVEV 166
Query: 318 HNKFGLLPETLYLALNIMDRFLCKELVQLEKLQLVGTACLFIASKYEEVYSPSVKHFAYE 377
H KF LPETL+LA+N++DRFL + +V+L KLQL+ CLFIA K+EEV P + +FAY
Sbjct: 167 HEKFHCLPETLFLAINLLDRFLSQNVVKLNKLQLLCITCLFIACKFEEVKLPKITNFAYV 226
Query: 378 TDGACDEEEIKEGEKFILKTLEFNLNYPNPMNFLRRISKADDYDIQSRTLAKYLLEISIV 437
TDGA E I++ E F+L +L +N++ PNP+NF+RRISKAD+Y I++R +AK+++E SI
Sbjct: 227 TDGAATVEGIRKAELFVLSSLGYNISLPNPLNFIRRISKADNYCIETRNMAKFIMEYSIC 286
Query: 438 DFKFIGILPSLCAAASMFLSRKMLGK-GQWDGNLIHYSGG 476
KFI + PS AA SM+++RK+ + +WD IHYSGG
Sbjct: 287 CNKFIHLKPSYLAAMSMYIARKIKNENSKWDETFIHYSGG 326
>YPR120c [D] KOG0653 Cyclin B and related kinase-activating proteins
Length = 435
Score = 218 bits (556), Expect = 1e-56
Identities = 127/351 (36%), Positives = 197/351 (55%), Gaps = 19/351 (5%)
Query: 199 GNSLAPMPIDENANNSASSVELR------AKQLQVEDSKKRPISTVVEQTLPKKFKVCEK 252
G+ A + +EN S+V+ R Q E+ ++ + KK ++ +
Sbjct: 78 GSKAAKVRREENIRPIVSAVQKRQIYNDRTAAEQEEEEEEEGEDDDAASIVNKKRRIDAE 137
Query: 253 GKE--YEWEDLDEEDINDPFMVSEYVTDIFEYLHRLEMMTLPNRHELF----KHANIQQN 306
G W+DLD + +D MV+EY +IF +L+R E+ TLP+ + L K+
Sbjct: 138 GVSEIVGWQDLDYVEKDDTAMVAEYSAEIFAFLYRRELETLPSHNYLLDKTSKYYLRPSM 197
Query: 307 RDILVNWMVKIHNKFGLLPETLYLALNIMDRFLCKELVQLEKLQLVGTACLFIASKYEEV 366
R ILV+W+V++H KF PETL+L++N+MDRFL K V + KLQL+ LFIA+K+EEV
Sbjct: 198 RTILVDWLVEVHEKFQCYPETLFLSINLMDRFLAKNKVTMNKLQLLAVTSLFIAAKFEEV 257
Query: 367 YSPSVKHFAYETDGACDEEEIKEGEKFILKTLEFNLNYPNPMNFLRRISKADDYDIQSRT 426
P + +AY TDGA + +IK E F+L +LEFN+ +PNP+NFLRRISKADDYD +R
Sbjct: 258 NLPKLAEYAYITDGAASKNDIKNAEMFMLTSLEFNIGWPNPLNFLRRISKADDYDPVNRN 317
Query: 427 LAKYLLEISIVDFKFIGILPSLCAAASMFLSRKMLGKGQ---WDGNLIHYSGGYT---KD 480
+ K++LE + +FI + PS +A +M+++R+M + + W+G L HYSGG +
Sbjct: 318 IGKFILEYAYCCHQFIHLPPSTVSAMAMYIARRMTNRNKNELWNGTLQHYSGGIDPIHDE 377
Query: 481 ELAPVCNMVMEYLVQPVVH-DELFKKYASRRFMKASVISRQWAKKVMSHNY 530
+C +++ + H D L KY R+ + +W M N+
Sbjct: 378 AFQSLCIDLVKDIASSKTHLDSLILKYKKPRYGSVYFQTFKWCTSEMHSNF 428
>Hs4757930 [D] KOG0653 Cyclin B and related kinase-activating proteins
Length = 398
Score = 217 bits (552), Expect = 4e-56
Identities = 129/336 (38%), Positives = 202/336 (59%), Gaps = 13/336 (3%)
Query: 200 NSLAPMPIDENAN-NSASSVELRAKQLQVEDSKKRPISTVVEQTLPKKFKVCEKGKEY-- 256
N+ P+ + N N K +Q+E + S E K+ +C+ +
Sbjct: 55 NTKVPVQPTKTTNVNKQLKPTASVKPVQMEKLAPKGPSPTPEDVSMKEENLCQAFSDALL 114
Query: 257 -EWEDLDEEDINDPFMVSEYVTDIFEYLHRLEMMTLPNRHELFKHANIQQNRDILVNWMV 315
+ ED+D ED +P + S+YV DI++YL +LE++ N H L + R ILV+W+V
Sbjct: 115 CKIEDIDNEDWENPQLCSDYVKDIYQYLRQLEVLQSINPHFLDGRDINGRMRAILVDWLV 174
Query: 316 KIHNKFGLLPETLYLALNIMDRFLCKELVQLEKLQLVGTACLFIASKYEEVYSPSVKHFA 375
++H+KF LL ETLY+ + IMDRFL + V +KLQLVG L +ASKYEE++SP+++ F
Sbjct: 175 QVHSKFRLLQETLYMCVGIMDRFLQVQPVSRKKLQLVGITALLLASKYEEMFSPNIEDFV 234
Query: 376 YETDGACDEEEIKEGEKFILKTLEFNLNYPNPMNFLRRISKADDYDIQSRTLAKYLLEIS 435
Y TD A +I+E E ILK L+F L P P++FLRR SKA + D++ TLAKYL+E++
Sbjct: 235 YITDNAYTSSQIREMETLILKELKFELGRPLPLHFLRRASKAGEVDVEQHTLAKYLMELT 294
Query: 436 IVDFKFIGILPSLCAAASMFLSRKMLGKGQWDGNLIHYSGGYTKDELAPVCNMVMEYLVQ 495
++D+ + PS AAA+ LS+K+LG+G+W+ +Y+ GYT++E+ V + + +V+
Sbjct: 295 LIDYDMVHYHPSKVAAAASCLSQKVLGQGKWNLKQQYYT-GYTENEVLEVMQHMAKNVVK 353
Query: 496 PVVHDELFK------KYASRRFMKASVISRQWAKKV 525
V++ L K KYAS + +K S+I + +K V
Sbjct: 354 --VNENLTKFIAIKNKYASSKLLKISMIPQLNSKAV 387
>YLR210w [D] KOG0653 Cyclin B and related kinase-activating proteins
Length = 460
Score = 212 bits (540), Expect = 1e-54
Identities = 108/261 (41%), Positives = 162/261 (61%), Gaps = 3/261 (1%)
Query: 263 EEDINDPFMVSEYVTDIFEYLHRLEMMTLPNRHELFKHANIQQN-RDILVNWMVKIHNKF 321
++D +D MV EY +DIF YL LE+ PN + + + R +++W+V++H +F
Sbjct: 195 DDDTHDVVMVVEYASDIFYYLRELEVKYRPNPYYMQNQVELTWPFRRTMIDWLVQLHFRF 254
Query: 322 GLLPETLYLALNIMDRFLCKELVQLEKLQLVGTACLFIASKYEEVYSPSVKHFAYETDGA 381
LLPETLYL +NI+DRFL K+ V L + QLVG + LFIA+K+EE+ P++ Y +
Sbjct: 255 QLLPETLYLTINIVDRFLSKKTVTLNRFQLVGVSALFIAAKFEEINCPTLDDLVYMLENT 314
Query: 382 CDEEEIKEGEKFILKTLEFNLNYPNPMNFLRRISKADDYDIQSRTLAKYLLEISIVDFKF 441
++I E++++ TLEF + +P PM FLRRISKADDYD + RTLAKYLLE +IV+ K
Sbjct: 315 YTRDDIIRAEQYMIDTLEFEIGWPGPMPFLRRISKADDYDFEPRTLAKYLLETTIVEPKL 374
Query: 442 IGILPSLCAAASMFLSRKMLGKGQWDGNLIHYSGGYTKDELAPVCNMVMEYLVQPV-VHD 500
+ PS AA + FLSR +LG W + YS GYT ++ P+ ++++E H
Sbjct: 375 VAAAPSWLAAGAYFLSRTILGSNDWSLKHVFYS-GYTSSQIIPLASLILENCKNASRRHH 433
Query: 501 ELFKKYASRRFMKASVISRQW 521
++KKY ++ + S I +W
Sbjct: 434 SIWKKYFDQKHYRCSQIVEEW 454
>Hs14327896 [D] KOG0653 Cyclin B and related kinase-activating proteins
Length = 433
Score = 186 bits (473), Expect = 6e-47
Identities = 113/324 (34%), Positives = 173/324 (52%), Gaps = 17/324 (5%)
Query: 204 PMPIDENANNSASSVELRAKQLQVEDSKKRPISTVVEQTLPKKFKVCEKGKEY--EWEDL 261
P P E +L + + V+ + P+ T P + +C+ + D+
Sbjct: 99 PEPEPEPEPEPVKEEKLSPEPILVDTASPSPMET--SGCAPAEEDLCQAFSDVILAVNDV 156
Query: 262 DEEDINDPFMVSEYVTDIFEYLHRLEMMTLPNRHELFKHANIQQNRDILVNWMVKIHNKF 321
D ED DP + SEYV DI+ YL +LE L R IL++W+V++ KF
Sbjct: 157 DAEDGADPNLCSEYVKDIYAYLRQLEEEQAVRPKYLLGREVTGNMRAILIDWLVQVQMKF 216
Query: 322 GLLPETLYLALNIMDRFLCKELVQLEKLQLVGTACLFIASKYEEVYSPSVKHFAYETDGA 381
LL ET+Y+ ++I+DRF+ V + LQLVG +FIASKYEE+Y P + FA+ TD
Sbjct: 217 RLLQETMYMTVSIIDRFMQNNCVPKKMLQLVGVTAMFIASKYEEMYPPEIGDFAFVTDNT 276
Query: 382 CDEEEIKEGEKFILKTLEFNLNYPNPMNFLRRISKADDYDIQSRTLAKYLLEISIVDFKF 441
+ +I++ E IL+ L F L P P++FLRR SK + D++ TLAKYL+E++++D+
Sbjct: 277 YTKHQIRQMEMKILRALNFGLGRPLPLHFLRRASKIGEVDVEQHTLAKYLMELTMLDYDM 336
Query: 442 IGILPSLCAAASMFLSRKMLGKGQWDGNLIHYSGGYTKDELAPVCNMVMEYLVQPVV--- 498
+ PS AA + L+ K+L G+W L HY YT++ L P VM++L + VV
Sbjct: 337 VHFPPSQIAAGAFCLALKILDNGEWTPTLQHYL-SYTEESLLP----VMQHLAKNVVMVN 391
Query: 499 -----HDELFKKYASRRFMKASVI 517
H + KYA+ + K S +
Sbjct: 392 QGLTKHMTVKNKYATSKHAKISTL 415
>ECU08g0260 [D] KOG0653 Cyclin B and related kinase-activating proteins
Length = 300
Score = 172 bits (436), Expect = 1e-42
Identities = 92/254 (36%), Positives = 154/254 (60%), Gaps = 6/254 (2%)
Query: 271 MVSEYVTDIFEYLHRLEMMTLPNRHELFKHANIQQNRDILVNWMVKIHNKFGLLPETLYL 330
MV +Y D+FEY T+ + R +LV+W++ IH+K GL +TL+L
Sbjct: 50 MVDKYSDDVFEYFS-----TIDKPFVYINDGVSWKMRSLLVDWIIDIHDKLGLCHDTLFL 104
Query: 331 ALNIMDRFLCKELVQLEKLQLVGTACLFIASKYEEVYSPSVKHFAYETDGACDEEEIKEG 390
A+N +DRFL + KLQLVG + L IA KYEEV P+++ T+ E++++
Sbjct: 105 AINFIDRFLSMRSIPSSKLQLVGISALMIACKYEEVVCPALQTLVLLTEKTLTGEDVRKA 164
Query: 391 EKFILKTLEFNLNYPNPMNFLRRISKADDYDIQSRTLAKYLLEISIVDFKFIGILPSLCA 450
EK++L TL ++L Y +P+NFLR+ SKA++Y+I SRT+ KYLLE+ + +F+ S+ A
Sbjct: 165 EKYMLHTLNYDLQYVSPLNFLRKCSKANNYEICSRTVGKYLLELMTLYEEFLRFKGSVRA 224
Query: 451 AASMFLSRKMLGKGQWDGNLIHYSGGYTKDELAPVCNMVMEYLVQPVVHDELFKKYASRR 510
AA+M+L+RK+ + Q I YS G+TKD++ N ++ + + + + + KY + +
Sbjct: 225 AAAMYLARKITSQDQCKNLFIMYS-GHTKDDIKECFNALVHTISESIPFENIQNKYNTPK 283
Query: 511 FMKASVISRQWAKK 524
F+ A+ +++A+K
Sbjct: 284 FLHAASFVKEYAEK 297
>At4g35620 [D] KOG0653 Cyclin B and related kinase-activating proteins
Length = 429
Score = 152 bits (383), Expect = 2e-36
Identities = 88/266 (33%), Positives = 154/266 (57%), Gaps = 7/266 (2%)
Query: 251 EKGKEYEWEDLDEEDINDPFMVSEYVTDIFEYLHRLEMMTLPNRHELFKHANIQQN-RDI 309
E+ +E D+DE D N+ EYV D++++ + E + + + +I R I
Sbjct: 148 EEEQEEPVLDIDEYDANNSLAAVEYVQDLYDFYRKTERFSCVPLDYMAQQFDISDKMRAI 207
Query: 310 LVNWMVKIHNKFGLLPETLYLALNIMDRFLCKELVQLEKLQLVGTACLFIASKYEEVYSP 369
L++W++++H+KF L+ ETL+L +N++DRFL K+ V +KLQLVG L +A KYEEV P
Sbjct: 208 LIDWLIEVHDKFELMNETLFLTVNLIDRFLSKQAVARKKLQLVGLVALLLACKYEEVSVP 267
Query: 370 SVKHFAYETDGACDEEEIKEGEKFILKTLEFNLNYPNPMNFLRRISKADDYDIQSRTLAK 429
V+ +D A ++ E EK +L TL+FN++ P FL+R KA D + LA
Sbjct: 268 IVEDLVVISDKAYTRTDVLEMEKIMLSTLQFNMSLPTQYPFLKRFLKAAQSDKKLEILAS 327
Query: 430 YLLEISIVDFKFIGILPSLCAAASMFLSRKML-GKGQWDGNLIHYSGGYTKDELAPVCNM 488
+L+E+++VD++ + PSL AA +++ ++ + G +W+ + + Y++++L C
Sbjct: 328 FLIELALVDYEMVRYPPSLLAATAVYTAQCTIHGFSEWN-STCEFHCHYSENQLLECCRR 386
Query: 489 VMEYLVQPVVHDEL---FKKYASRRF 511
++ L Q D+L +KY+S +F
Sbjct: 387 MVR-LHQKAGTDKLTGVHRKYSSSKF 411
>Hs4502611 [D] KOG0654 G2/Mitotic-specific cyclin A
Length = 465
Score = 147 bits (371), Expect = 4e-35
Identities = 91/263 (34%), Positives = 145/263 (54%), Gaps = 11/263 (4%)
Query: 264 EDIN----DPFMVSEYVTDIFEYLHRLEMMTLPNRHELFKHANIQQN-RDILVNWMVKIH 318
EDI+ D V+EY +I++YL E+ P H + K +I + R ILV+W+V++
Sbjct: 196 EDISSLGTDVINVTEYAEEIYQYLREAEIRHRPKAHYMKKQPDITEGMRTILVDWLVEVG 255
Query: 319 NKFGLLPETLYLALNIMDRFLCKELVQLEKLQLVGTACLFIASKYEEVYSPSVKHFAYET 378
++ L ETLYLA+N +DRFL V KLQLVGTA + +ASKYEE+Y P V F Y T
Sbjct: 256 EEYKLRAETLYLAVNFLDRFLSCMSVLRGKLQLVGTAAMLLASKYEEIYPPEVDEFVYIT 315
Query: 379 DGACDEEEIKEGEKFILKTLEFNLNYPNPMNFLRRISKADDYDIQSRTLAKYLLEISIVD 438
D + ++ + E +LK L F+L P FL + + +++ LAKY+ E+S+++
Sbjct: 316 DDTYTKRQLLKMEHLLLKVLAFDLTVPTTNQFLLQYLRRQGVCVRTENLAKYVAELSLLE 375
Query: 439 F-KFIGILPSLCAAASMFLSRKMLGKGQWDGNLIHYSGGYTKDELAPVCNMVMEYLVQPV 497
F+ LPSL AAA+ L+ + K W L ++ GY+ E+ P C + +
Sbjct: 376 ADPFLKYLPSLIAAAAFCLANYTVNKHFWPETLAAFT-GYSLSEIVP-CLSELHKAYLDI 433
Query: 498 VH---DELFKKYASRRFMKASVI 517
H + +KY + +++ S++
Sbjct: 434 PHRPQQAIREKYKASKYLCVSLM 456
>7291478 [D] KOG0653 Cyclin B and related kinase-activating proteins
Length = 530
Score = 147 bits (370), Expect = 5e-35
Identities = 98/297 (32%), Positives = 162/297 (53%), Gaps = 22/297 (7%)
Query: 237 TVVEQTLPKKFKVCEKGKEYEWEDLDEEDINDPFMVSEYVTDIFEYLHRLEMMTLPNRHE 296
T T+P + K + ED+D D + +VSEYV DI++YL+++E+ ++
Sbjct: 220 TTTTSTMPTTMSLSSK-RLAGIEDIDANDKENLVLVSEYVNDIYDYLYQVELEQPIHKDH 278
Query: 297 LFKHANIQQN-RDILVNWMVKIHNKFGLLPETLYLALNIMDRFLCKELVQLEK---LQLV 352
L + R +L++W+ ++H +F L ET LA+ I+DR+L ++V+ K LQLV
Sbjct: 279 LAGQKEVSHKMRAVLIDWINEVHLQFHLAAETFQLAVAIIDRYL--QVVKDTKRTYLQLV 336
Query: 353 GTACLFIASKYEEVYSPSVKHFAYETDGACDEEEIKEGEKFILKTLEFNLNYPNPMNFLR 412
G LFIA+KYEE++ P++ F + TD +I++ E I K ++ NL+ P P++FLR
Sbjct: 337 GVTALFIATKYEELFPPAIGDFVFITDDTYTARQIRQMELQIFKAIDCNLSRPLPIHFLR 396
Query: 413 RISKADDYDIQSRTLAKYLLEISIVDFKFIGILPSLCAAASMFLSRKML------GKG-- 464
R SKA + + T++KY +E++ VD++ PS AAAS+FLS +L G G
Sbjct: 397 RYSKAAGAEDEHHTMSKYFIELASVDYEMATYRPSEIAAASLFLSLHLLNGNHRAGTGFN 456
Query: 465 --QWDGNLIHYSGGYTKDELAPVCNMVMEYLVQPVVHDEL---FKKYASRRFMKASV 516
W L YS Y+ L P+ ++ + L + +L + KY +F K ++
Sbjct: 457 DRHWTPTLTFYS-RYSAAHLRPITRLIAK-LARDAPQAKLKAIYNKYQGSKFQKIAL 511
>SPBC16E9.17c [D] KOG0653 Cyclin B and related kinase-activating proteins
Length = 402
Score = 145 bits (367), Expect = 1e-34
Identities = 86/287 (29%), Positives = 153/287 (52%), Gaps = 7/287 (2%)
Query: 254 KEYEWEDLDEEDINDPFMVSEYVTDIFEYLHRLEMMTLPN-RHELFKHANIQQNRDILVN 312
+E E E+L D + EY +I ++ +LE+ +P+ RH + + + R ++N
Sbjct: 121 EEDEEEELQMRYSADESVSVEYAKEILSHMEKLEIRFMPDYRHMSAQPYYVTEMRASVIN 180
Query: 313 WMVKIHNKFGLLPETLYLALNIMDRFLCKELVQLEKLQLVGTACLFIASKYEEVYSPSVK 372
W+V +H LLPE+L+L++N++DRFL + V K++L G LFIA KYEE++ P+VK
Sbjct: 181 WIVGVHTCINLLPESLFLSINVLDRFLSLQNVPASKMKLCGATALFIACKYEEIHPPTVK 240
Query: 373 HFAYETDGACDEEEIKEGEKFILKTLEFNLNYPNPMNFLRRISKADDYDIQSRTLAKYLL 432
+G E+I EK++L L++ L +P P++FLR ++ + ++ Q R + KY L
Sbjct: 241 DLEIVLEGEWIGEDICGMEKYMLMVLQYQLGWPGPVSFLRLLTIVNKWESQLRIMIKYFL 300
Query: 433 EISIVDFKFIGILPSLCAAASMFLSRKMLGKGQWDGNLIHYSGGYTKDELAPVCNMVMEY 492
E+S+V+ +F + S A + + +L + W L + GY L +++++
Sbjct: 301 EVSLVEQRFSSLRASQLVATCAYTGQSILQEENWSNTLPQIT-GYDYMSLVSYVHLLLKC 359
Query: 493 LVQPVVHD-ELFKKYASRRFMKASVISRQWAKKVMSHNYDIMTLHDS 538
L P H ++ KYA+ F S W ++ N ++M + S
Sbjct: 360 LENPFDHHYAIYSKYATPYFHGISRQVHDW----IATNTNLMAMDGS 402
>At2g17620 [D] KOG0653 Cyclin B and related kinase-activating proteins
Length = 429
Score = 145 bits (367), Expect = 1e-34
Identities = 89/297 (29%), Positives = 161/297 (53%), Gaps = 16/297 (5%)
Query: 229 DSKKRPISTVVEQTLPKKFKVCEKGKEYEWEDLDEE---------DINDPFMVSEYVTDI 279
D ++ + + +L K + + +E E ED+ E D + EYV D+
Sbjct: 116 DEEEATLDLPMPMSLEKPYIEADPMEEVEMEDVTVEEPIVDIDVLDSKNSLAAVEYVQDL 175
Query: 280 FEYLHRLEMMTLPNRHELFKHANIQQN-RDILVNWMVKIHNKFGLLPETLYLALNIMDRF 338
+ + +E + + + ++ + R IL++W++++H+KF L+ ETL+L +N++DRF
Sbjct: 176 YAFYRTMERFSCVPVDYMMQQIDLNEKMRAILIDWLIEVHDKFDLINETLFLTVNLIDRF 235
Query: 339 LCKELVQLEKLQLVGTACLFIASKYEEVYSPSVKHFAYETDGACDEEEIKEGEKFILKTL 398
L K+ V +KLQLVG L +A KYEEV P V+ +D A ++ E EK +L TL
Sbjct: 236 LSKQNVMRKKLQLVGLVALLLACKYEEVSVPVVEDLVLISDKAYTRNDVLEMEKTMLSTL 295
Query: 399 EFNLNYPNPMNFLRRISKADDYDIQSRTLAKYLLEISIVDFKFIGILPSLCAAASMFLSR 458
+FN++ P FL+R KA D + LA +L+E+++V+++ + PSL AA S++ ++
Sbjct: 296 QFNISLPTQYPFLKRFLKAAQADKKCEVLASFLIELALVEYEMLRFPPSLLAATSVYTAQ 355
Query: 459 KML-GKGQWDGNLIHYSGGYTKDELAPVCNMVMEYLVQPVVHDEL---FKKYASRRF 511
L G +W+ + + Y++D+L C+ + L Q L ++KY++ +F
Sbjct: 356 CTLDGSRKWN-STCEFHCHYSEDQLME-CSRKLVSLHQRAATGNLTGVYRKYSTSKF 410
>At5g06150 [D] KOG0653 Cyclin B and related kinase-activating proteins
Length = 445
Score = 142 bits (359), Expect = 1e-33
Identities = 89/274 (32%), Positives = 146/274 (52%), Gaps = 12/274 (4%)
Query: 260 DLDEEDINDPFMVSEYVTDIFEYLHRLEMMTLPNRHELFKHANIQQN---RDILVNWMVK 316
D+DE D ++ EYV D++ + +E + P +++ H + N R IL++W+++
Sbjct: 167 DIDESDKDNHLAAVEYVDDMYSFYKEVEKESQP---KMYMHIQTEMNEKMRAILIDWLLE 223
Query: 317 IHNKFGLLPETLYLALNIMDRFLCKELVQLEKLQLVGTACLFIASKYEEVYSPSVKHFAY 376
+H KF L ETLYL +NI+DRFL + V +LQLVG + L IASKYEE++ P V Y
Sbjct: 224 VHIKFELNLETLYLTVNIIDRFLSVKAVPKRELQLVGISALLIASKYEEIWPPQVNDLVY 283
Query: 377 ETDGACDEEEIKEGEKFILKTLEFNLNYPNPMNFLRRISKADDYDIQSRTLAKYLLEISI 436
TD A +I EK IL LE+ L P FL R KA D + + +L E+ +
Sbjct: 284 VTDNAYSSRQILVMEKAILGNLEWYLTVPTQYVFLVRFIKASMSDPEMENMVHFLAELGM 343
Query: 437 VDFKFIGILPSLCAAASMFLSRKMLGKGQWDGNLIHYSGGYTKDELAPVCNMVMEYLVQP 496
+ + + PS+ AA++++ +R L K + + + GYT+ E+ C+ ++ +L
Sbjct: 344 MHYDTLTFCPSMLAASAVYTARCSLNKSPAWTDTLQFHTGYTESEIMD-CSKLLAFLHSR 402
Query: 497 VVHDEL---FKKYASRRFMKASVISRQWAKKVMS 527
L +KKY+ +++S AK ++S
Sbjct: 403 CGESRLRAVYKKYSKAENGGVAMVSP--AKSLLS 434
>At5g43080 [D] KOG0654 G2/Mitotic-specific cyclin A
Length = 355
Score = 142 bits (358), Expect = 1e-33
Identities = 87/243 (35%), Positives = 140/243 (56%), Gaps = 13/243 (5%)
Query: 260 DLDEEDINDPFMVSEYVTDIFEYLHRLEMMTLPNRHELFK-HANIQQN-RDILVNWMVKI 317
D+D +DP M YVT IFEYL +LE+ + P + K ++ N R +LV+W+V++
Sbjct: 73 DIDTRS-DDPQMCGPYVTSIFEYLRQLEVKSRPLVDYIEKIQKDVTSNMRGVLVDWLVEV 131
Query: 318 HNKFGLLPETLYLALNIMDRFLCKELVQLEKLQLVGTACLFIASKYEEVYSPSVKHFAYE 377
++ LL +TLYLA++ +DRFL + V ++LQL+G + IASKYEE+ P+V F Y
Sbjct: 132 AEEYKLLSDTLYLAVSYIDRFLSLKTVNKQRLQLLGVTSMLIASKYEEITPPNVDDFCYI 191
Query: 378 TDGACDEEEIKEGEKFILKTLEFNLNYPNPMNFLRRISKADDYD-----IQSRTLAKYLL 432
TD ++EI + E IL L+F L P FLRR ++ D +Q L YL
Sbjct: 192 TDNTYTKQEIVKMEADILLALQFELGNPTSNTFLRRFTRVAQEDFEMSHLQMEFLCSYLS 251
Query: 433 EISIVDFKFIGILPSLCAAASMFLSRKMLGKGQWDGNLI-----HYSGGYTKDELAPVCN 487
E+S++D++ + LPS AA+++FL+R ++ Q N++ Y G K+ +A + +
Sbjct: 252 ELSMLDYQSVKFLPSTVAASAVFLARFIIRPKQHPWNVMLEEYTRYKAGDLKECVAMIHD 311
Query: 488 MVM 490
+ +
Sbjct: 312 LYL 314
>SPCC4E9.02 [D] KOG0653 Cyclin B and related kinase-activating proteins
Length = 310
Score = 141 bits (355), Expect = 3e-33
Identities = 75/191 (39%), Positives = 115/191 (59%), Gaps = 1/191 (0%)
Query: 232 KRPISTVVEQTLPKKFKVCEKGKEYEWEDLDEEDINDPFMVSEYVTDIFEYLHRLEMMTL 291
K + T+ E T + E + E+ DP MV +Y +IF Y+ LE
Sbjct: 120 KHRLPTIPEWTKEDLAALSEAAARLQANPSPEDIETDPSMVPDYDPEIFHYMQSLERKLA 179
Query: 292 PNRHELFKHANIQQ-NRDILVNWMVKIHNKFGLLPETLYLALNIMDRFLCKELVQLEKLQ 350
P + + I R +LV+W+V++ F LLPETL+LA+N++DRFL ++V L+K+Q
Sbjct: 180 PPPNYMSVQQEIDWVTRHMLVDWIVQVQIHFRLLPETLFLAVNLIDRFLSIKVVSLQKVQ 239
Query: 351 LVGTACLFIASKYEEVYSPSVKHFAYETDGACDEEEIKEGEKFILKTLEFNLNYPNPMNF 410
LVG + L IA KYEE++ PS+ +FA+ G +EI E+++L L+F++++P PM+F
Sbjct: 240 LVGLSALLIACKYEEIHPPSIYNFAHVVQGIFTVDEIIRAERYMLMLLDFDISWPGPMSF 299
Query: 411 LRRISKADDYD 421
LRRIS+AD YD
Sbjct: 300 LRRISRADSYD 310
>At1g80370 [D] KOG0654 G2/Mitotic-specific cyclin A
Length = 461
Score = 140 bits (354), Expect = 4e-33
Identities = 84/265 (31%), Positives = 140/265 (52%), Gaps = 18/265 (6%)
Query: 230 SKKRPISTVVEQTLPKKFKVCEKGKEYEWEDLDEEDINDPFMVSEYVTDIFEYLH--RLE 287
S RP TV C ++ D+D +D DP + S Y DI+ L L+
Sbjct: 161 SPPRPFGTVERS--------CGGASSPKFVDIDSDD-KDPLLCSLYAPDIYYNLRVAELK 211
Query: 288 MMTLPNRHELFKHANIQQNRDILVNWMVKIHNKFGLLPETLYLALNIMDRFLCKELVQLE 347
P+ E + + R ILV+W+V++ ++ L+P+TLYL + ++D FL V+ +
Sbjct: 212 RRPFPDFMEKTQRDVTETMRGILVDWLVEVSEEYTLVPDTLYLTVYLIDWFLHGNYVERQ 271
Query: 348 KLQLVGTACLFIASKYEEVYSPSVKHFAYETDGACDEEEIKEGEKFILKTLEFNLNYPNP 407
+LQL+G C+ IASKYEE+++P ++ F + TD +++ E E +LK F + P
Sbjct: 272 RLQLLGITCMLIASKYEEIHAPRIEEFCFITDNTYTRDQVLEMESQVLKHFSFQIYTPTS 331
Query: 408 MNFLRRISKA-----DDYDIQSRTLAKYLLEISIVDFKFIGILPSLCAAASMFLSRKMLG 462
FLRR +A + ++ LA YL E++++D+ F+ LPS+ AA+++FL++ L
Sbjct: 332 KTFLRRFLRAAQVSFPNQSLEMEFLANYLTELTLMDYPFLKFLPSIIAASAVFLAKWTLN 391
Query: 463 KGQ--WDGNLIHYSGGYTKDELAPV 485
+ W+ L HY+ D A V
Sbjct: 392 QSSHPWNPTLEHYTTYKASDLKASV 416
>At1g20610 [D] KOG0653 Cyclin B and related kinase-activating proteins
Length = 429
Score = 140 bits (352), Expect = 6e-33
Identities = 92/294 (31%), Positives = 153/294 (51%), Gaps = 18/294 (6%)
Query: 213 NSASSVELRAKQLQVEDSKKRPIST----VVEQTLPKKFKVCEKGKEYEWEDLDEE---- 264
+S SS E + V++S K + V+ T ++ + KE E ED D+E
Sbjct: 101 DSVSSEEPETIIIDVDESDKEGGDSNEPMFVQHTEAMLEEIEQMEKEIEMEDADKEEEPV 160
Query: 265 ------DINDPFMVSEYVTDIFEYLHRLEMMTL--PNRHELFKHANIQQNRDILVNWMVK 316
D N+P EY+ D+ + E ++ PN + + N ++ R IL++W+++
Sbjct: 161 IDIDACDKNNPLAAVEYIHDMHTFYKNFEKLSCVPPNYMDNQQDLN-ERMRGILIDWLIE 219
Query: 317 IHNKFGLLPETLYLALNIMDRFLCKELVQLEKLQLVGTACLFIASKYEEVYSPSVKHFAY 376
+H KF L+ ETLYL +N++DRFL + +KLQLVG L +A KYEEV P V
Sbjct: 220 VHYKFELMEETLYLTINVIDRFLAVHQIVRKKLQLVGVTALLLACKYEEVSVPVVDDLIL 279
Query: 377 ETDGACDEEEIKEGEKFILKTLEFNLNYPNPMNFLRRISKADDYDIQSRTLAKYLLEISI 436
+D A E+ + EK + TL+FN + P P F++R KA D + L+ +++E+ +
Sbjct: 280 ISDKAYSRREVLDMEKLMANTLQFNFSLPTPYVFMKRFLKAAQSDKKLEILSFFMIELCL 339
Query: 437 VDFKFIGILPSLCAAASMFLSRKML-GKGQWDGNLIHYSGGYTKDELAPVCNMV 489
V+++ + LPS AA++++ ++ L G +W ++G K LA MV
Sbjct: 340 VEYEMLEYLPSKLAASAIYTAQCTLKGFEEWSKTCEFHTGYNEKQLLACARKMV 393
>At1g47210 [D] KOG0654 G2/Mitotic-specific cyclin A
Length = 372
Score = 139 bits (351), Expect = 8e-33
Identities = 85/226 (37%), Positives = 131/226 (57%), Gaps = 12/226 (5%)
Query: 260 DLDEEDINDPFMVSEYVTDIFEYLHRLEMMT----LPNRHELFKHANIQQNRDILVNWMV 315
D+D +DP M YV DI+EYL +LE+ LP+ E + R +LV+W+V
Sbjct: 88 DIDSRS-DDPQMCGPYVADIYEYLRQLEVKPKQRPLPDYIEKVQKDVTPSMRGVLVDWLV 146
Query: 316 KIHNKFGLLPETLYLALNIMDRFLCKELVQLEKLQLVGTACLFIASKYEEVYSPSVKHFA 375
++ ++ L ETLYL ++ +DRFL + V +KLQLVG + + IASKYEE+ P V F
Sbjct: 147 EVAEEYKLGSETLYLTVSHIDRFLSLKTVNKQKLQLVGVSAMLIASKYEEISPPKVDDFC 206
Query: 376 YETDGACDEEEIKEGEKFILKTLEFNLNYPNPMNFLRRISKA--DDYDI---QSRTLAKY 430
Y TD ++++ + E IL L+F L P F+RR ++ DD+ + Q L Y
Sbjct: 207 YITDNTFSKQDVVKMEADILLALQFELGRPTINTFMRRFTRVAQDDFKVPHLQLEPLCCY 266
Query: 431 LLEISIVDFKFIGILPSLCAAASMFLSRKMLGKGQ--WDGNLIHYS 474
L E+SI+D+K + +PSL AA+++FL+R ++ Q W+ L Y+
Sbjct: 267 LSELSILDYKTVKFVPSLLAASAVFLARFIIRPKQHPWNQMLEEYT 312
>At2g26760 [D] KOG0653 Cyclin B and related kinase-activating proteins
Length = 387
Score = 138 bits (347), Expect = 2e-32
Identities = 86/254 (33%), Positives = 142/254 (55%), Gaps = 8/254 (3%)
Query: 260 DLDEEDINDPFMVSEYVTDIFEYLHRLEMMTLPNRHELFKHANIQQNRDILVNWMVKIHN 319
D+D D N+ EYV DIF++ +E + + ++ R IL++W+V +H
Sbjct: 115 DIDAVDANNELAAVEYVEDIFKFYRTVEEEGGIKDYIGSQPEINEKMRSILIDWLVDVHR 174
Query: 320 KFGLLPETLYLALNIMDRFLCKELVQLEKLQLVGTACLFIASKYEEVYSPSVKHFAYETD 379
KF L+PETLYL +N++DRFL +V +LQL+G + IA KYEE+++P V F +D
Sbjct: 175 KFELMPETLYLTINLVDRFLSLTMVHRRELQLLGLGAMLIACKYEEIWAPEVNDFVCISD 234
Query: 380 GACDEEEIKEGEKFILKTLEFNLNYPNPMNFLRRISKAD-DYDIQSRTLAKYLLEISIVD 438
A + +++ EK IL +E+ + P P FL R KA D + L YL E+ ++
Sbjct: 235 NAYNRKQVLAMEKSILGQVEWYITVPTPYVFLARYVKAAVPCDAEMEKLVFYLAELGLMQ 294
Query: 439 FKFIGI-LPSLCAAASMFLSRKMLGKGQ-WDGNLIHYSGGYTKDELAPVCNMVMEYLVQP 496
+ + + PS+ AA++++ +R++L K W L H++ GY++DE+ M+M+ L
Sbjct: 295 YPIVVLNRPSMLAASAVYAARQILKKTPFWTETLKHHT-GYSEDEIMEHAKMLMK-LRDS 352
Query: 497 VVHDEL---FKKYA 507
+L FKKY+
Sbjct: 353 ASESKLIAVFKKYS 366
>At5g11300 [D] KOG0654 G2/Mitotic-specific cyclin A
Length = 434
Score = 137 bits (345), Expect = 4e-32
Identities = 80/235 (34%), Positives = 132/235 (56%), Gaps = 11/235 (4%)
Query: 263 EEDINDPFMVSEYVTDIFEYLHRLEMMTLP--NRHELFKHANIQQNRDILVNWMVKIHNK 320
+ ++ DP S Y DI++ +H E+ P N EL + R IL++W+V++ +
Sbjct: 160 DSNVEDPQCCSLYAADIYDNIHVAELQQRPLANYMELVQRDIDPDMRKILIDWLVEVSDD 219
Query: 321 FGLLPETLYLALNIMDRFLCKELVQLEKLQLVGTACLFIASKYEEVYSPSVKHFAYETDG 380
+ L+P+TLYL +N++DRFL ++ ++LQL+G +C+ IASKYEE+ +P V+ F + T
Sbjct: 220 YKLVPDTLYLTVNLIDRFLSNSYIERQRLQLLGVSCMLIASKYEELSAPGVEEFCFITAN 279
Query: 381 ACDEEEIKEGEKFILKTLEFNLNYPNPMNFLRRISKADDYD---IQSRTLAKYLLEISIV 437
E+ E IL + F L+ P FL + I+ LA YL E+++V
Sbjct: 280 TYTRPEVLSMEIQILNFVHFRLSVPTTKTFLSALFLIIILQVPFIELEYLANYLAELTLV 339
Query: 438 DFKFIGILPSLCAAASMFLSRKMLGKGQ--WDGNLIHYSGGYTKDELAPVCNMVM 490
++ F+ LPSL AA+++FL+R L + W+ L H YT+ E+A + N V+
Sbjct: 340 EYSFLRFLPSLIAASAVFLARWTLDQTDHPWNPTLQH----YTRYEVAELKNTVL 390
>At1g77390 [D] KOG0654 G2/Mitotic-specific cyclin A
Length = 454
Score = 137 bits (344), Expect = 5e-32
Identities = 82/236 (34%), Positives = 130/236 (54%), Gaps = 9/236 (3%)
Query: 263 EEDINDPFMVSEYVTDIFEYLHRLEMMTLP--NRHELFKHANIQQNRDILVNWMVKIHNK 320
+ D+ DP + + + DI+E+L E+ P + E + + R IL++W+V++ +
Sbjct: 166 DSDLMDPQLCASFACDIYEHLRVSEVNKRPALDYMERTQSSINASMRSILIDWLVEVAEE 225
Query: 321 FGLLPETLYLALNIMDRFLCKELVQLEKLQLVGTACLFIASKYEEVYSPSVKHFAYETDG 380
+ L PETLYLA+N +DR+L + + LQL+G C+ IA+KYEEV P V+ F Y TD
Sbjct: 226 YRLSPETLYLAVNYVDRYLTGNAINKQNLQLLGVTCMMIAAKYEEVCVPQVEDFCYITDN 285
Query: 381 ACDEEEIKEGEKFILKTLEFNLNYPNPMNFLRRISKA-----DDYDIQSRTLAKYLLEIS 435
E+ E E +L L+F L P FLRR +A + + S LA YL E+S
Sbjct: 286 TYLRNELLEMESSVLNYLKFELTTPTAKCFLRRFLRAAQGRKEVPSLLSECLACYLTELS 345
Query: 436 IVDFKFIGILPSLCAAASMFLSRKML--GKGQWDGNLIHYSGGYTKDELAPVCNMV 489
++D+ + PSL AA+++FL++ L + W+ L HY+ K A V N++
Sbjct: 346 LLDYAMLRYAPSLVAASAVFLAQYTLHPSRKPWNATLEHYTSYRAKHMEACVKNLL 401
>At3g11520 [D] KOG0653 Cyclin B and related kinase-activating proteins
Length = 427
Score = 136 bits (342), Expect = 9e-32
Identities = 87/271 (32%), Positives = 142/271 (52%), Gaps = 6/271 (2%)
Query: 260 DLDEEDINDPFMVSEYVTDIFEYLHRLEMMTLPNRHELFKHANIQQNRDILVNWMVKIHN 319
D+D D + EYV D++ + + + P + + ++ R IL++W+V++H
Sbjct: 157 DIDYVDKENDLAAVEYVEDMYIFYKEVVNESKPQMYMHTQPEIDEKMRSILIDWLVEVHV 216
Query: 320 KFGLLPETLYLALNIMDRFLCKELVQLEKLQLVGTACLFIASKYEEVYSPSVKHFAYETD 379
KF L PETLYL +NI+DRFL + V +LQLVG + L IASKYEE++ P V Y TD
Sbjct: 217 KFDLSPETLYLTVNIIDRFLSLKTVPRRELQLVGVSALLIASKYEEIWPPQVNDLVYVTD 276
Query: 380 GACDEEEIKEGEKFILKTLEFNLNYPNPMNFLRRISKADDYDIQSRTLAKYLLEISIVDF 439
+ + +I EK IL LE+ L P FL R KA D + L +L E+ ++
Sbjct: 277 NSYNSRQILVMEKTILGNLEWYLTVPTQYVFLVRFIKASGSDQKLENLVHFLAELGLMHH 336
Query: 440 KFIGILPSLCAAASMFLSRKMLGKGQWDGNLIHYSGGYTKDELAPVCNMVMEYLVQPVVH 499
+ PS+ AA++++ +R L K + + + GY++ +L C+ ++ ++
Sbjct: 337 DSLMFCPSMLAASAVYTARCCLNKTPTWTDTLKFHTGYSESQLMD-CSKLLAFIHSKAGE 395
Query: 500 DEL---FKKYASRRFMKASVISRQWAKKVMS 527
+L KKY+ ++IS AK +MS
Sbjct: 396 SKLRGVLKKYSKLGRGAVALISP--AKSLMS 424
>At1g15570 [D] KOG0654 G2/Mitotic-specific cyclin A
Length = 450
Score = 134 bits (336), Expect = 5e-31
Identities = 78/235 (33%), Positives = 128/235 (54%), Gaps = 10/235 (4%)
Query: 260 DLDEEDINDPFMVSEYVTDIFEYLH--RLEMMTLPNRHELFKHANIQQNRDILVNWMVKI 317
D+D +D DP + Y +I L L+ LP+ E + Q R ILV+W+V++
Sbjct: 174 DIDSDD-KDPLLCCLYAPEIHYNLRVSELKRRPLPDFMERIQKDVTQSMRGILVDWLVEV 232
Query: 318 HNKFGLLPETLYLALNIMDRFLCKELVQLEKLQLVGTACLFIASKYEEVYSPSVKHFAYE 377
++ L +TLYL + ++D FL VQ ++LQL+G C+ IASKYEE+ +P ++ F +
Sbjct: 233 SEEYTLASDTLYLTVYLIDWFLHGNYVQRQQLQLLGITCMLIASKYEEISAPRIEEFCFI 292
Query: 378 TDGACDEEEIKEGEKFILKTLEFNLNYPNPMNFLRRISKADDY-----DIQSRTLAKYLL 432
TD +++ E E +LK F + P P FLRR +A ++ LA YL
Sbjct: 293 TDNTYTRDQVLEMENQVLKHFSFQIYTPTPKTFLRRFLRAAQASRLSPSLEVEFLASYLT 352
Query: 433 EISIVDFKFIGILPSLCAAASMFLSRKMLGKGQ--WDGNLIHYSGGYTKDELAPV 485
E++++D+ F+ LPS+ AA+++FL++ + + W+ L HY+ D A V
Sbjct: 353 ELTLIDYHFLKFLPSVVAASAVFLAKWTMDQSNHPWNPTLEHYTTYKASDLKASV 407
>At1g44110 [D] KOG0654 G2/Mitotic-specific cyclin A
Length = 460
Score = 133 bits (334), Expect = 8e-31
Identities = 72/217 (33%), Positives = 127/217 (58%), Gaps = 11/217 (5%)
Query: 268 DPFMVSEYVTDIFEYLHRLEMMTLPN---RHELFKHANIQQNRDILVNWMVKIHNKFGLL 324
DP + + + DI+++L E P+ + K N R ILV+W++++ ++ L+
Sbjct: 187 DPQLCATFACDIYKHLRASEAKKRPDVDYMERVQKDVNSSM-RGILVDWLIEVSEEYRLV 245
Query: 325 PETLYLALNIMDRFLCKELVQLEKLQLVGTACLFIASKYEEVYSPSVKHFAYETDGACDE 384
PETLYL +N +DR+L ++ +KLQL+G AC+ IA+KYEE+ +P V+ F Y TD +
Sbjct: 246 PETLYLTVNYIDRYLSGNVISRQKLQLLGVACMMIAAKYEEICAPQVEEFCYITDNTYLK 305
Query: 385 EEIKEGEKFILKTLEFNLNYPNPMNFLRRISKA-----DDYDIQSRTLAKYLLEISIVDF 439
+E+ + E +L L+F + P FLRR +A + +Q +A Y+ E+S++++
Sbjct: 306 DEVLDMESDVLNYLKFEMTAPTTKCFLRRFVRAAHGVHEAPLMQLECMANYIAELSLLEY 365
Query: 440 KFIGILPSLCAAASMFLSRKMLG--KGQWDGNLIHYS 474
+ PSL AA+++FL++ +L + W+ L HY+
Sbjct: 366 TMLSHSPSLVAASAIFLAKYILDPTRRPWNSTLQHYT 402
>At4g37490 [D] KOG0653 Cyclin B and related kinase-activating proteins
Length = 428
Score = 132 bits (333), Expect = 1e-30
Identities = 89/293 (30%), Positives = 149/293 (50%), Gaps = 6/293 (2%)
Query: 204 PMPIDENANNSASSVELRAKQLQVEDSKKRPISTVVEQTLPKKFKVC--EKGKEYEWEDL 261
P +D +S S EL + + + K+ +T + C EK ++ + D+
Sbjct: 92 PKVVDVIEISSDSDEELGLVAAREKKATKKKATTYTSVLTARSKAACGLEKKQKEKIVDI 151
Query: 262 DEEDINDPFMVSEYVTDIFEYLHRLEMMTLPNRHELFKHANIQQNRDILVNWMVKIHNKF 321
D D+ + EYV DI+ + +E P + + ++ R ILV W++ +H +F
Sbjct: 152 DSADVENDLAAVEYVEDIYSFYKSVESEWRPRDYMASQPDINEKMRLILVEWLIDVHVRF 211
Query: 322 GLLPETLYLALNIMDRFLCKELVQLEKLQLVGTACLFIASKYEEVYSPSVKHFAYETDGA 381
L PET YL +NI+DRFL + V ++LQLVG + L +++KYEE++ P V+ D A
Sbjct: 212 ELNPETFYLTVNILDRFLSVKPVPRKELQLVGLSALLMSAKYEEIWPPQVEDLVDIADHA 271
Query: 382 CDEEEIKEGEKFILKTLEFNLNYPNPMNFLRRISKADDYDIQSRTLAKYLLEISIVDF-K 440
++I EK IL TLE+ L P FL R KA D + + YL E+ ++ +
Sbjct: 272 YSHKQILVMEKTILSTLEWYLTVPTHYVFLARFIKASIADEKMENMVHYLAELGVMHYDT 331
Query: 441 FIGILPSLCAAASMFLSRKMLGKGQ-WDGNLIHYSGGYTKDELAPVCNMVMEY 492
I PS+ AA++++ +R L + W L H++ GY++ +L C ++ Y
Sbjct: 332 MIMFSPSMVAASAIYAARSSLRQVPIWTSTLKHHT-GYSETQLMD-CAKLLAY 382
>At1g47220 [D] KOG0654 G2/Mitotic-specific cyclin A
Length = 327
Score = 132 bits (332), Expect = 1e-30
Identities = 79/208 (37%), Positives = 119/208 (56%), Gaps = 10/208 (4%)
Query: 260 DLDEEDINDPFMVSEYVTDIFEYLHRLE----MMTLPNRHELFKHANIQQNRDILVNWMV 315
D+D +DP M YV+DI+EYL LE + L + E + R +LV+W+V
Sbjct: 42 DIDARS-DDPQMCGLYVSDIYEYLRELEVKPKLRPLHDYIEKIQEDITPSKRGVLVDWLV 100
Query: 316 KIHNKFGLLPETLYLALNIMDRFLCKELVQLEKLQLVGTACLFIASKYEEVYSPSVKHFA 375
++ +F L+ ETLYL ++ +DRFL ++V LQLVG + +FIASKYEE P V+ F
Sbjct: 101 EVAEEFELVSETLYLTVSYIDRFLSLKMVNEHWLQLVGVSAMFIASKYEEKRRPKVEDFC 160
Query: 376 YETDGACDEEEIKEGEKFILKTLEFNLNYPNPMNFLRRISKADDYD-----IQSRTLAKY 430
Y T ++++ + E+ IL LEF L P FLRR + D +Q L Y
Sbjct: 161 YITANTYTKQDVLKMEEDILLALEFELGRPTTNTFLRRFIRVAQEDFKVPNLQLEPLCCY 220
Query: 431 LLEISIVDFKFIGILPSLCAAASMFLSR 458
L E+S++D+ + +PSL AA+++FL+R
Sbjct: 221 LSELSMLDYSCVKFVPSLLAASAVFLAR 248
>At5g25380 [D] KOG0654 G2/Mitotic-specific cyclin A
Length = 444
Score = 131 bits (330), Expect = 2e-30
Identities = 75/240 (31%), Positives = 133/240 (55%), Gaps = 19/240 (7%)
Query: 263 EEDINDPFMVSEYVTDIFEYLHRLEMMTLPNRHELFKHANIQQN-----RDILVNWMVKI 317
+ + DP S Y I++ ++ E+ P+ + + +Q++ R IL++W+V++
Sbjct: 168 DSGVQDPQFCSLYAASIYDSINVAELEQRPSTSYMVQ---VQRDIDPTMRGILIDWLVEV 224
Query: 318 HNKFGLLPETLYLALNIMDRFLCKELVQLEKLQLVGTACLFIASKYEEVYSPSVKHFAYE 377
++ L+ +TLYL +N++DRF+ ++ +KLQL+G C+ IASKYEE+ +P ++ F +
Sbjct: 225 SEEYKLVSDTLYLTVNLIDRFMSHNYIEKQKLQLLGITCMLIASKYEEISAPRLEEFCFI 284
Query: 378 TDGACDEEEIKEGEKFILKTLEFNLNYPNPMNFLRRISKADDYD-----IQSRTLAKYLL 432
TD E+ E +L +L F L+ P FLRR +A I+ LA Y
Sbjct: 285 TDNTYTRLEVLSMEIKVLNSLHFRLSVPTTKTFLRRFIRAAQASDKVPLIEMEYLANYFA 344
Query: 433 EISIVDFKFIGILPSLCAAASMFLSRKMLGKGQ--WDGNLIHYSGGYTKDELAPVCNMVM 490
E+++ ++ F+ LPSL AA+++FL+R L + W+ L H YT+ E + + N V+
Sbjct: 345 ELTLTEYTFLRFLPSLIAASAVFLARWTLDQSNHPWNQTLQH----YTRYETSALKNTVL 400
>At1g16330 [D] KOG0653 Cyclin B and related kinase-activating proteins
Length = 518
Score = 131 bits (330), Expect = 2e-30
Identities = 83/287 (28%), Positives = 150/287 (51%), Gaps = 3/287 (1%)
Query: 209 ENANNSASSVELRAKQLQVEDSKKRPISTVVEQTLPKKFKVCEK-GKEYEWEDLDE-EDI 266
+ ++S+ + + K L V K L K EK G+ E E L +D
Sbjct: 197 QGESSSSGNKDPTTKVLDVTAKPKSKRRKSFTSLLVNGSKFDEKNGETTEPEKLPSIDDE 256
Query: 267 NDPFMVSEYVTDIFEYLHRLEMMTLPNRHELFKHANIQQ-NRDILVNWMVKIHNKFGLLP 325
++ V+EYV DI+++ E + H L HA + R IL+NW++++H KF L+
Sbjct: 257 SNQLEVAEYVDDIYQFYWTAEALNPALGHYLSAHAEVSPVTRGILINWLIEVHFKFDLMH 316
Query: 326 ETLYLALNIMDRFLCKELVQLEKLQLVGTACLFIASKYEEVYSPSVKHFAYETDGACDEE 385
ETLYL ++++DR+L + + ++QL+G L +ASKYE+ + P +K + + E
Sbjct: 317 ETLYLTMDLLDRYLSQVPIHKNEMQLIGLTALLLASKYEDYWHPRIKDLISISAESYTRE 376
Query: 386 EIKEGEKFILKTLEFNLNYPNPMNFLRRISKADDYDIQSRTLAKYLLEISIVDFKFIGIL 445
+I E+ +LK L+F LN P P F+ R KA + + LA YL+E+ +V+++ +
Sbjct: 377 QILGMERSMLKQLKFRLNAPTPYVFMLRFLKAAQSNKKLEQLAFYLIELCLVEYEALKYK 436
Query: 446 PSLCAAASMFLSRKMLGKGQWDGNLIHYSGGYTKDELAPVCNMVMEY 492
PSL A++++++R L +L++ Y ++ +M++ +
Sbjct: 437 PSLLCASAIYVARCTLHMTPVWTSLLNNHTHYNVSQMKDCSDMILRF 483
>At1g47230 [D] KOG0654 G2/Mitotic-specific cyclin A
Length = 369
Score = 127 bits (318), Expect = 6e-29
Identities = 76/218 (34%), Positives = 121/218 (54%), Gaps = 11/218 (5%)
Query: 268 DPFMVSEYVTDIFEYLHRLE----MMTLPNRHELFKHANIQQNRDILVNWMVKIHNKFGL 323
DP M + +DI YL +E LP+ E + R +LV+W+V++ ++ L
Sbjct: 88 DPQMCEPFASDICAYLREMEGKPKHRPLPDYIEKVQSDLTPHMRAVLVDWLVEVAEEYKL 147
Query: 324 LPETLYLALNIMDRFLCKELVQLEKLQLVGTACLFIASKYEEVYSPSVKHFAYETDGACD 383
+ +TLYL ++ +DRFL + + +KLQLVG + + IASKYEE+ P V+ F Y TD
Sbjct: 148 VSDTLYLTISYVDRFLSVKPINRQKLQLVGVSAMLIASKYEEIGPPKVEDFCYITDNTFT 207
Query: 384 EEEIKEGEKFILKTLEFNLNYPNPMNFLRRISKA-----DDYDIQSRTLAKYLLEISIVD 438
++E+ E IL L+F L P FLRR ++ D +Q L YL E+S++D
Sbjct: 208 KQEVVSMEADILLALQFELGSPTIKTFLRRFTRVAQEDFKDSQLQIEFLCCYLSELSMLD 267
Query: 439 FKFIGILPSLCAAASMFLSRKMLGKGQ--WDGNLIHYS 474
+ + LPSL +A+++FL+R ++ Q W+ L Y+
Sbjct: 268 YTCVKYLPSLLSASAVFLARFIIRPKQHPWNQMLEEYT 305
>Hs14719420_2 [D] KOG0653 Cyclin B and related kinase-activating proteins
Length = 1284
Score = 127 bits (318), Expect = 6e-29
Identities = 87/275 (31%), Positives = 138/275 (49%), Gaps = 5/275 (1%)
Query: 222 AKQLQVEDSKKRPISTVVEQTLPKKFKVCEKGKEYEW---EDLDEEDINDPFMVSEYVTD 278
A V S+ S+ E K KG E ED+DE D +DP Y +
Sbjct: 963 ATMTSVGKSRTTTESSACESASDKPVSPQAKGTPKEITPREDIDE-DSSDPSFNPMYAKE 1021
Query: 279 IFEYLHRLEMMTLPNRHELFKHANIQQNRDILVNWMVKIHNKFGLLPETLYLALNIMDRF 338
IF Y+ E + + + R ILV+W+V++ F + ETLYLA+ ++D +
Sbjct: 1022 IFSYMKEREEQFILTDYMNRQIEITSDMRAILVDWLVEVQVSFEMTHETLYLAVKLVDLY 1081
Query: 339 LCKELVQLEKLQLVGTACLFIASKYEEVYSPSVKHFAYETDGACDEEEIKEGEKFILKTL 398
L K + + +KLQL+G IA+K+EE SP V F Y D E+ E IL L
Sbjct: 1082 LMKAVCKKDKLQLLGATAFMIAAKFEEHNSPRVDDFVYICDDNYQRSEVLSMEINILNVL 1141
Query: 399 EFNLNYPNPMNFLRRISKADDYDIQSRTLAKYLLEISIVDFKFIGILPSLCAAASMFLSR 458
+ ++N P +FLRR ++ ++++ TL++Y+ E+++ ++ ++ S AAAS+ L+
Sbjct: 1142 KCDINIPIAYHFLRRYARCIHTNMKTLTLSRYICEMTLQEYHYVQEKASKLAAASLLLAL 1201
Query: 459 KMLGKGQWDGNLIHYSGGYTKDELAPVCNMVMEYL 493
M G W L HYS GY+ EL P+ + + L
Sbjct: 1202 YMKKLGYWVPFLEHYS-GYSISELHPLVRQLNKLL 1235
>Hs4502613 [D] KOG0654 G2/Mitotic-specific cyclin A
Length = 432
Score = 124 bits (312), Expect = 3e-28
Identities = 86/265 (32%), Positives = 141/265 (52%), Gaps = 9/265 (3%)
Query: 259 EDLDEEDINDPFMVSEYVTDIFEYLHRLEMMTLPNRHELFKHANIQQN-RDILVNWMVKI 317
ED +N+ V +Y DI YL +E+ P + K +I + R ILV+W+V++
Sbjct: 165 EDEKPVSVNE---VPDYHEDIHTYLREMEVKCKPKVGYMKKQPDITNSMRAILVDWLVEV 221
Query: 318 HNKFGLLPETLYLALNIMDRFLCKELVQLEKLQLVGTACLFIASKYEEVYSPSVKHFAYE 377
++ L ETL+LA+N +DRFL V KLQLVGTA + +ASK+EE+Y P V F Y
Sbjct: 222 GEEYKLQNETLHLAVNYIDRFLSSMSVLRGKLQLVGTAAMLLASKFEEIYPPEVAEFVYI 281
Query: 378 TDGACDEEEIKEGEKFILKTLEFNLNYPNPMNFLRR-ISKADDYDIQSRTLAKYLLEISI 436
TD ++++ E +LK L F+L P FL + + + +LA +L E+S+
Sbjct: 282 TDDTYTKKQVLRMEHLVLKVLTFDLAAPTVNQFLTQYFLHQQPANCKVESLAMFLGELSL 341
Query: 437 VDF-KFIGILPSLCAAASMFLSRKMLGKGQWDGNLIHYSGGYTKDELAP-VCNMVMEYLV 494
+D ++ LPS+ A A+ L+ + W +LI + GYT + L P + ++ YL
Sbjct: 342 IDADPYLKYLPSVIAGAAFHLALYTVTGQSWPESLIRKT-GYTLESLKPCLMDLHQTYLK 400
Query: 495 QPV-VHDELFKKYASRRFMKASVIS 518
P + +KY + ++ S+++
Sbjct: 401 APQHAQQSIREKYKNSKYHGVSLLN 425
>At1g76310 [D] KOG0653 Cyclin B and related kinase-activating proteins
Length = 457
Score = 124 bits (310), Expect = 5e-28
Identities = 77/252 (30%), Positives = 128/252 (50%), Gaps = 30/252 (11%)
Query: 260 DLDEEDINDPFMVSEYVTDIFEYLHRLEMM---------------------------TLP 292
D+D D N+P V EY+ DI+ + + E+ +P
Sbjct: 162 DIDSCDKNNPLSVVEYINDIYCFYKKNEVTFSVLFLYHYDHSSFKIETFSIILQCRSCVP 221
Query: 293 NRHELFKHANIQQNRDILVNWMVKIHNKFGLLPETLYLALNIMDRFLC-KELVQLEKLQL 351
+ +H ++ R IL +W++++H KF L+ ETLYL +N++DRFL + + +KLQL
Sbjct: 222 PNYMENQHDINERMRGILFDWLIEVHYKFELMEETLYLTINLIDRFLAVHQHIARKKLQL 281
Query: 352 VGTACLFIASKYEEVYSPSVKHFAYETDGACDEEEIKEGEKFILKTLEFNLNYPNPMNFL 411
VG + +A KYEEV P V +D A EI + EK + TL+FN P P F+
Sbjct: 282 VGVTAMLLACKYEEVSVPVVDDLILISDKAYTRTEILDMEKLMANTLQFNFCLPTPYVFM 341
Query: 412 RRISKADDYDIQSRTLAKYLLEISIVDFKFIGILPSLCAAASMFLSRKML-GKGQWDGNL 470
RR KA D + L+ +++E+ +V+++ + PS AA++++ ++ L G W
Sbjct: 342 RRFLKAAQSDKKLELLSFFMIELCLVEYEMLQYTPSQLAASAIYTAQSTLKGYEDW-SKT 400
Query: 471 IHYSGGYTKDEL 482
+ GYT++ L
Sbjct: 401 SEFHSGYTEEAL 412
>7294661 [D] KOG0654 G2/Mitotic-specific cyclin A
Length = 490
Score = 123 bits (309), Expect = 6e-28
Identities = 71/201 (35%), Positives = 115/201 (56%), Gaps = 2/201 (0%)
Query: 272 VSEYVTDIFEYLHRLEMMTLPNRHELFKHANIQQN-RDILVNWMVKIHNKFGLLPETLYL 330
V +Y DI EY E P + + +I N R IL++W+V++ ++ L ETLYL
Sbjct: 199 VVQYQMDILEYFRESEKKHRPKPLYMRRQKDISHNMRSILIDWLVEVSEEYKLDTETLYL 258
Query: 331 ALNIMDRFLCKELVQLEKLQLVGTACLFIASKYEEVYSPSVKHFAYETDGACDEEEIKEG 390
++ +DRFL + V KLQLVGTA ++IA+KYEE+Y P V F + TD + + ++
Sbjct: 259 SVFYLDRFLSQMAVVRSKLQLVGTAAMYIAAKYEEIYPPEVGEFVFLTDDSYTKAQVLRM 318
Query: 391 EKFILKTLEFNLNYPNPMNFLRRISKADDYDIQSRTLAKYLLEISIVDFK-FIGILPSLC 449
E+ ILK L F+L P F+ + D + + + Y+ E+S+++ + ++ LPSL
Sbjct: 319 EQVILKILSFDLCTPTAYVFINTYAVLCDMPEKLKYMTLYISELSLMEGETYLQYLPSLM 378
Query: 450 AAASMFLSRKMLGKGQWDGNL 470
++AS+ L+R +LG W L
Sbjct: 379 SSASVALARHILGMEMWTPRL 399
>CE27776 [D] KOG0653 Cyclin B and related kinase-activating proteins
Length = 383
Score = 121 bits (303), Expect = 3e-27
Identities = 90/339 (26%), Positives = 167/339 (48%), Gaps = 29/339 (8%)
Query: 213 NSASSVELRA--KQLQVEDSKKRPISTV------VEQTLPKKFKVCEKGKEYEWEDLDEE 264
+S ELRA +++ +K+ P+ VE P+K + + Y D D E
Sbjct: 43 HSKGLTELRAHISGFKIDSAKRDPLGKSRTSRRDVENLPPQKSRYVDPCPHY---DYDLE 99
Query: 265 DINDPFMVSEYVTDIFEYLHRLEMMTLPNRHELFKHANIQ-QNRDILVNWMVKIHNKFGL 323
+ +P +S+Y IF+Y E+ ++ L KH + + R IL++WMV+I F L
Sbjct: 100 EAGNPDSISDYAQGIFDYYRHREVHFRVRKY-LHKHPEVDVKTRAILIDWMVEIQETFEL 158
Query: 324 LPETLYLALNIMDRFLCK-ELVQLEKLQLVGTACLFIASKYEEVYSPSVKHFAYETDGAC 382
ETLY A+ + D +LCK + V +Q + +FIA+KY+E P V Y +
Sbjct: 159 NHETLYNAVKLTDMYLCKTKNVDKNTIQKLACVAIFIAAKYDERSPPLVDDLIYLSGDRF 218
Query: 383 DEEEIKEGEKFILKTLEFNLNYPNPMNFLRRISKADDYDIQSRTLAKYLLEISIVDFKFI 442
+E+ E+ + T+ ++L P +LRR + D+++ T+ +++LE S++ +++
Sbjct: 219 SRDELLAMERELFATVGYDLGSPLSYRYLRRFGRVCRVDMKTLTMGRFILETSLMVYEYA 278
Query: 443 GILPSLCAAASMFLSRKMLGKG---QWDGNLIHYSGGYTKDELAPVCNMVMEYLVQPVVH 499
+ S AAA+ L+ +ML K +W+ L YS G+T +E+ P+ V H
Sbjct: 279 MVSQSRLAAAAFVLAMRMLDKNNEYEWNPVLEKYS-GFTGEEVMPL-----------VEH 326
Query: 500 DELFKKYASRRFMKASVISRQWAKKVMSHNYDIMTLHDS 538
++ ++ + + + ++++ +V H I L D+
Sbjct: 327 MNHILHFSKDKWAQLTSVRQKYSHEVFFHVASIPMLPDT 365
>CE13315 [D] KOG0653 Cyclin B and related kinase-activating proteins
Length = 384
Score = 121 bits (303), Expect = 3e-27
Identities = 90/339 (26%), Positives = 167/339 (48%), Gaps = 29/339 (8%)
Query: 213 NSASSVELRA--KQLQVEDSKKRPISTV------VEQTLPKKFKVCEKGKEYEWEDLDEE 264
+S ELRA +++ +K+ P+ VE P+K + + Y D D E
Sbjct: 44 HSKGLTELRAHISGFKIDSAKRDPLGKSRTSRRDVENLPPQKSRYVDPCPHY---DYDLE 100
Query: 265 DINDPFMVSEYVTDIFEYLHRLEMMTLPNRHELFKHANIQ-QNRDILVNWMVKIHNKFGL 323
+ +P +S+Y IF+Y E+ ++ L KH + + R IL++WMV+I F L
Sbjct: 101 EAGNPDSISDYAQGIFDYYRHREVHFRVRKY-LHKHPEVDVKTRAILIDWMVEIQETFEL 159
Query: 324 LPETLYLALNIMDRFLCK-ELVQLEKLQLVGTACLFIASKYEEVYSPSVKHFAYETDGAC 382
ETLY A+ + D +LCK + V +Q + +FIA+KY+E P V Y +
Sbjct: 160 NHETLYNAVKLTDMYLCKTKNVDKNTIQKLACVAIFIAAKYDERSPPLVDDLIYLSGDRF 219
Query: 383 DEEEIKEGEKFILKTLEFNLNYPNPMNFLRRISKADDYDIQSRTLAKYLLEISIVDFKFI 442
+E+ E+ + T+ ++L P +LRR + D+++ T+ +++LE S++ +++
Sbjct: 220 SRDELLAMERELFATVGYDLGSPLSYRYLRRFGRVCRVDMKTLTMGRFILETSLMVYEYA 279
Query: 443 GILPSLCAAASMFLSRKMLGKG---QWDGNLIHYSGGYTKDELAPVCNMVMEYLVQPVVH 499
+ S AAA+ L+ +ML K +W+ L YS G+T +E+ P+ V H
Sbjct: 280 MVSQSRLAAAAFVLAMRMLDKNNEYEWNPVLEKYS-GFTGEEVMPL-----------VEH 327
Query: 500 DELFKKYASRRFMKASVISRQWAKKVMSHNYDIMTLHDS 538
++ ++ + + + ++++ +V H I L D+
Sbjct: 328 MNHILHFSKDKWAQLTSVRQKYSHEVFFHVASIPMLPDT 366
>CE23835 [D] KOG0653 Cyclin B and related kinase-activating proteins
Length = 339
Score = 107 bits (266), Expect = 6e-23
Identities = 74/258 (28%), Positives = 135/258 (51%), Gaps = 19/258 (7%)
Query: 278 DIFEYL-HRLEMMTLPNRHELFKHANIQQNRDILVNWMVKIHNKFGLLPETLYLALNIMD 336
DI+ YL H + L + + N + R ILV+W+V++H +F L PETL+L + ++D
Sbjct: 56 DIYNYLVHHEKKYVLDDSFINGGNVNSKMRR-ILVDWLVQVHLRFHLTPETLHLTIFVLD 114
Query: 337 RFLCKELVQLEKLQLVGTACLFIASKYEEVYSPSVKHFAYETDGACDEEEIKEGEKFILK 396
R + K +V + QL+G A LF+ASK+E++Y P + + T+ +++I E+ IL
Sbjct: 115 RIIVKNIVSKAEFQLLGVAALFVASKFEDIYLPDILEYELITENTFSKKQILAMEQTILN 174
Query: 397 TLEFNLNYPNPMNFLRRISKA----DDYDIQSRT------LAKYLLEISIVDFKFIGILP 446
L F+L+ P+ + FLR ISK D I T ++K L E++++D +
Sbjct: 175 ALNFDLSCPSSLVFLRYISKTLTENDVNPIDKETFYYVHNISKCLGELALLDSVMSTVPR 234
Query: 447 SLCAAASMFLSRKMLG----KGQWDGNLIHYSGGYTKDELAPVCNMVMEYLVQPVVHDEL 502
S A+ASM ++ ++ + ++I G +K ++ +++ + + H +L
Sbjct: 235 SHVASASMIITLNIISVDGINPKTAASMIRKQFGASKQDIYDAISLLAQVAYKNFRHQKL 294
Query: 503 F---KKYASRRFMKASVI 517
+KY S +F + S +
Sbjct: 295 CAIREKYQSSKFGRVSYL 312
>CE28122 [D] KOG0653 Cyclin B and related kinase-activating proteins
Length = 317
Score = 105 bits (261), Expect = 2e-22
Identities = 72/258 (27%), Positives = 134/258 (51%), Gaps = 19/258 (7%)
Query: 278 DIFEYL-HRLEMMTLPNRHELFKHANIQQNRDILVNWMVKIHNKFGLLPETLYLALNIMD 336
DI+ YL H + L + + N + R ILV+W++++H +F L PETL+L + ++D
Sbjct: 34 DIYNYLVHHEKKYVLDDSFINGGNVNSKMRR-ILVDWLIQVHLRFHLTPETLHLTIFVLD 92
Query: 337 RFLCKELVQLEKLQLVGTACLFIASKYEEVYSPSVKHFAYETDGACDEEEIKEGEKFILK 396
R + K +V + QL+G A LF+ASK+E++Y P + + TD +++I E+ IL
Sbjct: 93 RIIVKNIVSKAEFQLLGVAALFVASKFEDIYLPDILEYEMITDNTFSKKQIMAMEQTILN 152
Query: 397 TLEFNLNYPNPMNFLRRISKA-DDYDIQS---------RTLAKYLLEISIVDFKFIGILP 446
L F+L+ P+ + FLR ISK + D+ ++K L E++++D +
Sbjct: 153 ALNFDLSCPSSLVFLRCISKTLTENDVNPIDKEAFYYVHNISKCLGELALLDSVMSTVPR 212
Query: 447 SLCAAASMFLSRKMLG----KGQWDGNLIHYSGGYTKDELAPVCNMVMEYLVQPVVHDEL 502
S A+ASM ++ ++ + ++I G +K ++ ++ + + H +L
Sbjct: 213 SHVASASMIITLNVITVDGINPKTAASMIRKQLGASKQDIYDAIALLAQVAYKNFRHQKL 272
Query: 503 F---KKYASRRFMKASVI 517
+KY S +F + S +
Sbjct: 273 CAIREKYQSSKFGRVSYL 290
>Hs16306525_2 [D] KOG0653 Cyclin B and related kinase-activating proteins
Length = 221
Score = 102 bits (254), Expect = 1e-21
Identities = 60/173 (34%), Positives = 98/173 (55%), Gaps = 1/173 (0%)
Query: 321 FGLLPETLYLALNIMDRFLCKELVQLEKLQLVGTACLFIASKYEEVYSPSVKHFAYETDG 380
F + ETLYLA+ ++D +L K + + +KLQL+G IA+K+EE SP V F Y D
Sbjct: 1 FEMTHETLYLAVKLVDLYLMKAVCKKDKLQLLGATAFMIAAKFEEHNSPRVDDFVYICDD 60
Query: 381 ACDEEEIKEGEKFILKTLEFNLNYPNPMNFLRRISKADDYDIQSRTLAKYLLEISIVDFK 440
E+ E IL L+ ++N P +FLRR ++ ++++ TL++Y+ E+++ ++
Sbjct: 61 NYQRSEVLSMEINILNVLKCDINIPIAYHFLRRYARCIHTNMKTLTLSRYICEMTLQEYH 120
Query: 441 FIGILPSLCAAASMFLSRKMLGKGQWDGNLIHYSGGYTKDELAPVCNMVMEYL 493
++ S AAAS+ L+ M G W L HYS GY+ EL P+ + + L
Sbjct: 121 YVQEKASKLAAASLLLALYMKKLGYWVPFLEHYS-GYSISELHPLVRQLNKLL 172
>CE06570 [D] KOG0653 Cyclin B and related kinase-activating proteins
Length = 361
Score = 99.8 bits (247), Expect = 9e-21
Identities = 63/190 (33%), Positives = 107/190 (56%), Gaps = 10/190 (5%)
Query: 278 DIFEYLHRLEMMTLPNRHELFKHANIQQNRDILVNWMVKIHNKFGLLPETLYLALNIMDR 337
DI++YL E L + + R ILV+W+V++H +F L PETL+L + I+DR
Sbjct: 81 DIYKYLVHHEKKYLLEECFMEGGEPTPKMRRILVDWLVQVHVRFHLTPETLHLTVFILDR 140
Query: 338 FLCKELVQLEKLQLVGTACLFIASKYEEVYSPSVKHFAYETDGACDEEEIKEGEKFILKT 397
L K++ LQL+G + +F+ASK+EEVY P + + + T+ +++I E+ IL +
Sbjct: 141 MLQKKVTSKADLQLLGISAMFVASKFEEVYLPDIHDYEFITENTYSKKQILAMEQTILNS 200
Query: 398 LEFNLNYPNPMNFLRRISK------ADDYDIQ----SRTLAKYLLEISIVDFKFIGILPS 447
L F+L+ P+ + FLR +S+ A D Q + ++K L E++++D S
Sbjct: 201 LNFDLSCPSSLVFLRCLSRILSENDASPIDNQAFCYTYNISKCLGELALLDSVMASTPRS 260
Query: 448 LCAAASMFLS 457
A+ASM ++
Sbjct: 261 HIASASMIIA 270
>CE03820 [D] KOG0654 G2/Mitotic-specific cyclin A
Length = 485
Score = 97.8 bits (242), Expect = 4e-20
Identities = 76/284 (26%), Positives = 132/284 (45%), Gaps = 10/284 (3%)
Query: 240 EQTLPKKFKVCEKGKEYEWEDLDEEDINDPFMVSEYVTDIFEY-LHRLEMMTLPNR--HE 296
E K+F E K+ + + E + F E+ DI +Y LHR NR HE
Sbjct: 177 ENQRKKEFGKEEAVKKIQKKAAKEARDDSMFSSEEFFPDIIKYMLHR----QTKNRASHE 232
Query: 297 LFKHANI--QQNRDILVNWMVKIHNKFGLLPETLYLALNIMDRFLCKELVQLEKLQLVGT 354
F + ++ R IL++W + ++ ET +LA++++DR L + + QLVGT
Sbjct: 233 CFDIQSQVNEEMRTILIDWFSDVVKEYNFQKETFHLAVSLVDRALSMFNIDKMRFQLVGT 292
Query: 355 ACLFIASKYEEVYSPSVKHFAYETDGACDEEEIKEGEKFILKTLEFNLNYPNPMNFLRRI 414
+ IA KYEE++ P ++ FA TD +I E+F+L +F + P F
Sbjct: 293 TSMMIAVKYEEIFPPEIEDFALITDNTYRVPDILLMERFLLGKFDFVVAMPTSSWFGTCF 352
Query: 415 SKADDYDIQSRTLAKYLLEISIVDFKFIGILPSLCAAASMFLSRKMLGKGQWDGNLIHYS 474
+K ++ + R YLLE+S++D F+ PS AAA+ + W ++ +
Sbjct: 353 AKRMNFTKKMRNTVHYLLELSLIDVHFLRYRPSDIAAAACCFANLQADVESWPQKMVDDT 412
Query: 475 GGYTKDELAPVCNMVMEYL-VQPVVHDELFKKYASRRFMKASVI 517
G T+D + + ++ YL +F Y+ M+ +++
Sbjct: 413 GISTEDFVDVLRDLHRMYLNASTADFKSIFYNYSETAQMEVALL 456
>Hs22062947 [D] KOG0653 Cyclin B and related kinase-activating proteins
Length = 403
Score = 92.4 bits (228), Expect = 2e-18
Identities = 54/148 (36%), Positives = 92/148 (61%), Gaps = 9/148 (6%)
Query: 392 KFILKTLEFNLNYPNPMNFLRRISKADDYDIQSRTLAKYLLEISIVDFKFIGILPSLCAA 451
K ILK L+F + P P++FLR+ SKA D++ TLAKYL+E++++D+ + PS A
Sbjct: 256 KLILKELKFEVGGPLPLHFLRQASKAGKADVEQHTLAKYLMELTLIDYDMMHYHPSKAAT 315
Query: 452 ASMFLSRKMLGKGQWDGNLIHYSGGYTKDELAPVCNMVMEYLVQPVVHDELFK------K 505
A+ LS+K+LG+G+W+ Y+ GYT++E+ V V + +++ V++ L K K
Sbjct: 316 AASCLSQKVLGQGKWNLKQQCYT-GYTQNEVLEVMQHVAKNVLK--VNENLTKFIAIKNK 372
Query: 506 YASRRFMKASVISRQWAKKVMSHNYDIM 533
YAS +F+K S+I + +K + + +M
Sbjct: 373 YASNKFLKISMIPQLNSKAIKDLAFPLM 400
>7298245 [D] KOG0655 G1/S-specific cyclin E
Length = 709
Score = 91.3 bits (225), Expect = 3e-18
Identities = 49/136 (36%), Positives = 81/136 (59%), Gaps = 5/136 (3%)
Query: 297 LFKHANIQQN-RDILVNWMVKIHNKFGLLPETLYLALNIMDRFL-CKELVQLEKLQLVGT 354
L +H +Q R IL++W++++ + L ET YLA++ +DR+L VQ LQL+G
Sbjct: 351 LEQHPGLQPRMRAILLDWLIEVCEVYKLHRETFYLAVDYLDRYLHVAHKVQKTHLQLIGI 410
Query: 355 ACLFIASKYEEVYSPSVKHFAYETDGACDEEEIKEGEKFILKTLEFNLNYPNPMNFLRRI 414
CLF+A+K EE+Y P + FAY TDGAC E +I EK +L+ L++++ +P+ +
Sbjct: 411 TCLFVAAKVEEIYPPKIGEFAYVTDGACTERDILNHEKILLQALDWDI---SPITITGWL 467
Query: 415 SKADDYDIQSRTLAKY 430
++ +RT A +
Sbjct: 468 GVYMQLNVNNRTPASF 483
>Hs17318567 [D] KOG0655 G1/S-specific cyclin E
Length = 296
Score = 90.5 bits (223), Expect = 6e-18
Identities = 48/112 (42%), Positives = 73/112 (64%), Gaps = 2/112 (1%)
Query: 293 NRHELFKHANIQ-QNRDILVNWMVKIHNKFGLLPETLYLALNIMDRF-LCKELVQLEKLQ 350
++H H++++ Q R IL++W++++ + L ET YLA + DRF L ++ + LQ
Sbjct: 19 DKHFEVLHSDLEPQMRSILLDWLLEVCEVYTLHRETFYLAQDFFDRFMLTQKDINKNMLQ 78
Query: 351 LVGTACLFIASKYEEVYSPSVKHFAYETDGACDEEEIKEGEKFILKTLEFNL 402
L+G LFIASK EE+Y+P ++ FAY TDGAC EE+I E ILK L++ L
Sbjct: 79 LIGITSLFIASKLEEIYAPKLQEFAYVTDGACSEEDILRMELIILKALKWEL 130
>Hs17318565 [D] KOG0655 G1/S-specific cyclin E
Length = 404
Score = 90.5 bits (223), Expect = 6e-18
Identities = 48/112 (42%), Positives = 73/112 (64%), Gaps = 2/112 (1%)
Query: 293 NRHELFKHANIQ-QNRDILVNWMVKIHNKFGLLPETLYLALNIMDRF-LCKELVQLEKLQ 350
++H H++++ Q R IL++W++++ + L ET YLA + DRF L ++ + LQ
Sbjct: 127 DKHFEVLHSDLEPQMRSILLDWLLEVCEVYTLHRETFYLAQDFFDRFMLTQKDINKNMLQ 186
Query: 351 LVGTACLFIASKYEEVYSPSVKHFAYETDGACDEEEIKEGEKFILKTLEFNL 402
L+G LFIASK EE+Y+P ++ FAY TDGAC EE+I E ILK L++ L
Sbjct: 187 LIGITSLFIASKLEEIYAPKLQEFAYVTDGACSEEDILRMELIILKALKWEL 238
>Hs22048740 [D] KOG0655 G1/S-specific cyclin E
Length = 148
Score = 87.8 bits (216), Expect = 4e-17
Identities = 45/97 (46%), Positives = 64/97 (65%), Gaps = 1/97 (1%)
Query: 307 RDILVNWMVKIHNKFGLLPETLYLALNIMDRF-LCKELVQLEKLQLVGTACLFIASKYEE 365
R IL++W++++ + L ET YLA + DRF L ++ + LQL+G LFIASK EE
Sbjct: 2 RSILLDWLLEVCEVYTLHRETFYLAQDFFDRFMLTQKDINKNMLQLIGITSLFIASKLEE 61
Query: 366 VYSPSVKHFAYETDGACDEEEIKEGEKFILKTLEFNL 402
+Y+P ++ FAY TDGAC EE+I E ILK L++ L
Sbjct: 62 IYAPKLQEFAYVTDGACSEEDILRMELIILKALKWEL 98
>Hs17318561 [D] KOG0655 G1/S-specific cyclin E
Length = 395
Score = 85.5 bits (210), Expect = 2e-16
Identities = 48/128 (37%), Positives = 78/128 (60%), Gaps = 2/128 (1%)
Query: 278 DIFEYLHRLEMMTLPNRHELFKHANIQQN-RDILVNWMVKIHNKFGLLPETLYLALNIMD 336
++++ + E L ++H L +H +Q R IL++W++++ + L ET YLA + D
Sbjct: 100 EVWKIMLNKEKTYLRDQHFLEQHPLLQPKMRAILLDWLMEVCEVYKLHRETFYLAQDFFD 159
Query: 337 RFLC-KELVQLEKLQLVGTACLFIASKYEEVYSPSVKHFAYETDGACDEEEIKEGEKFIL 395
R++ +E V LQL+G + LFIA+K EE+Y P + FAY TDGAC +EI E I+
Sbjct: 160 RYMATQENVVKTLLQLIGISSLFIAAKLEEIYPPKLHQFAYVTDGACSGDEILTMELMIM 219
Query: 396 KTLEFNLN 403
K L++ L+
Sbjct: 220 KALKWRLS 227
>Hs17318559 [D] KOG0655 G1/S-specific cyclin E
Length = 410
Score = 85.5 bits (210), Expect = 2e-16
Identities = 48/128 (37%), Positives = 78/128 (60%), Gaps = 2/128 (1%)
Query: 278 DIFEYLHRLEMMTLPNRHELFKHANIQQN-RDILVNWMVKIHNKFGLLPETLYLALNIMD 336
++++ + E L ++H L +H +Q R IL++W++++ + L ET YLA + D
Sbjct: 115 EVWKIMLNKEKTYLRDQHFLEQHPLLQPKMRAILLDWLMEVCEVYKLHRETFYLAQDFFD 174
Query: 337 RFLC-KELVQLEKLQLVGTACLFIASKYEEVYSPSVKHFAYETDGACDEEEIKEGEKFIL 395
R++ +E V LQL+G + LFIA+K EE+Y P + FAY TDGAC +EI E I+
Sbjct: 175 RYMATQENVVKTLLQLIGISSLFIAAKLEEIYPPKLHQFAYVTDGACSGDEILTMELMIM 234
Query: 396 KTLEFNLN 403
K L++ L+
Sbjct: 235 KALKWRLS 242
>At1g20590 [D] KOG0653 Cyclin B and related kinase-activating proteins
Length = 199
Score = 83.2 bits (204), Expect = 9e-16
Identities = 47/146 (32%), Positives = 80/146 (54%), Gaps = 2/146 (1%)
Query: 338 FLCKELVQLEKLQLVGTACLFIASKYEEVYSPSVKHFAYETDGACDEEEIKEGEKFILKT 397
FL + +KLQLVG L +A KYEEV P V +D A E+ + EK + T
Sbjct: 3 FLAVHQIVRKKLQLVGVTALLLACKYEEVSVPVVDDLILISDKAYSRREVLDMEKLMANT 62
Query: 398 LEFNLNYPNPMNFLRRISKADDYDIQSRTLAKYLLEISIVDFKFIGILPSLCAAASMFLS 457
L+FN + P P F++R KA D + L+ +++E+ +V+++ + LPS AA++++ +
Sbjct: 63 LQFNFSLPTPYVFMKRFLKAAQSDKKLEILSFFMIELCLVEYEMLEYLPSKLAASAIYTA 122
Query: 458 RKML-GKGQWDGNLIHYSGGYTKDEL 482
+ L G +W + GY +++L
Sbjct: 123 QCTLKGFEEW-SKTCEFHTGYNEEQL 147
>CE24832 [D] KOG0655 G1/S-specific cyclin E
Length = 524
Score = 79.0 bits (193), Expect = 2e-14
Identities = 96/436 (22%), Positives = 175/436 (40%), Gaps = 85/436 (19%)
Query: 55 TANSYSNTKPAPLRDDIMVPEDKENYNPL-AKIDEREELDSNLVHNHKSLGTQKHVTIDE 113
TA T+ + I+ P D+ L ID +E + N S+G+QK +
Sbjct: 9 TAERVPTTQKPERKSAILSPHDELRERLLETAIDMKENIPQRNTRN-SSVGSQKSDCSET 67
Query: 114 RQEIIGYSHLDTEKSAPSSSTYSSEHTENDGVHDVNPNVQRSDNEADFKMQTTNAFHENV 173
R+ + K P++ +S E N D + ++ + ++ +
Sbjct: 68 RKR-------RSTKEGPAAKRHSGEKHRNGSREDSLEYISEYSDDREVGSSSSQSSRTR- 119
Query: 174 NXXXXXXXXXXXXXXXXNECPAVNVGNSLAPMPIDENANNSASSVELRAKQLQVEDSKKR 233
G L MP +E + +SS + A+ + + +
Sbjct: 120 -------------------------GQPLPAMPEEEEVFDKSSSSDNLAESEESHEMVRL 154
Query: 234 PISTVVEQTLPKKFK-----VCEKGKEYEWEDLDEED---------------INDPFMVS 273
+E+ + F V +EYE + ++ED +ND MV+
Sbjct: 155 EERQDIEEEIEDDFDDEEEDVVNDKEEYEEIESEDEDDYPVQNEGFAVTKRLMNDEHMVT 214
Query: 274 EYV-------------TDIFEYLHRLEMMTLPNRHELFKHANIQ-QNRDILVNWMVKIHN 319
T ++ + + + + R L H ++ + R IL++WM+++
Sbjct: 215 APTFLSTAKCDGIGSPTKVWSLMVKRDEIPRATRFLLGNHPDMDDEKRRILIDWMMEVCE 274
Query: 320 KFGLLPETLYLALNIMDRFLCKELVQL--EKLQLVGTACLFIASKYEEVYSPSVKHFAYE 377
L ET +LA++ +DR+L V+ + QLVGTA LFIA+KYEE+Y P FA+
Sbjct: 275 SEKLHRETFHLAVDYVDRYLESSNVECSTDNFQLVGTAALFIAAKYEEIYPPKCIDFAHL 334
Query: 378 TDGACDEEEIKEGEKFILKTLEFNLNYPNPMNFLR---------RISKADDYDIQSRTL- 427
TD A + I+ E I+K + ++L + +L + +K+D Y+ Q+ +
Sbjct: 335 TDSAFTCDNIRTMEVLIVKYIGWSLGPITSIQWLSTYLQLLGTGKKNKSDHYEEQNMYVP 394
Query: 428 ----AKYLLEISIVDF 439
++YL I+DF
Sbjct: 395 ELLRSEYLEMCKILDF 410
>HsM4502615 [D] KOG0656 G1/S-specific cyclin D
Length = 295
Score = 77.8 bits (190), Expect = 4e-14
Identities = 48/152 (31%), Positives = 80/152 (52%), Gaps = 4/152 (2%)
Query: 307 RDILVNWMVKIHNKFGLLPETLYLALNIMDRFLCKELVQLEKLQLVGTACLFIASKYEEV 366
R I+ WM+++ + E LA+N +DRFL E V+ +LQL+G C+F+ASK +E
Sbjct: 57 RKIVATWMLEVCEEQKCEEEVFPLAMNYLDRFLSLEPVKKSRLQLLGATCMFVASKMKET 116
Query: 367 YSPSVKHFAYETDGACDEEEIKEGEKFILKTLEFNLNYPNP----MNFLRRISKADDYDI 422
+ + TDG+ EE+ + E ++ L++NL P +FL ++ +A++
Sbjct: 117 IPLTAEKLCIYTDGSIRPEELLQMELLLVNKLKWNLAAMTPHDFIEHFLSKMPEAEENKQ 176
Query: 423 QSRTLAKYLLEISIVDFKFIGILPSLCAAASM 454
R A+ + D KFI PS+ AA S+
Sbjct: 177 IIRKHAQTFVASCATDVKFISNPPSMVAAGSV 208
>Hs16950655 [D] KOG0656 G1/S-specific cyclin D
Length = 295
Score = 77.0 bits (188), Expect = 7e-14
Identities = 47/152 (30%), Positives = 80/152 (51%), Gaps = 4/152 (2%)
Query: 307 RDILVNWMVKIHNKFGLLPETLYLALNIMDRFLCKELVQLEKLQLVGTACLFIASKYEEV 366
R I+ WM+++ + E LA+N +DRFL E V+ +LQL+G C+F+ASK +E
Sbjct: 57 RKIVATWMLEVCEEQKCEEEVFPLAMNYLDRFLSLEPVKKSRLQLLGATCMFVASKMKET 116
Query: 367 YSPSVKHFAYETDGACDEEEIKEGEKFILKTLEFNLNYPNP----MNFLRRISKADDYDI 422
+ + TD + EE+ + E ++ L++NL P +FL ++ +A++
Sbjct: 117 IPLTAEKLCIYTDNSIRPEELLQMELLLVNKLKWNLAAMTPHDFIEHFLSKMPEAEENKQ 176
Query: 423 QSRTLAKYLLEISIVDFKFIGILPSLCAAASM 454
R A+ + + D KFI PS+ AA S+
Sbjct: 177 IIRKHAQTFVALCATDVKFISNPPSMVAAGSV 208
>At4g34160 [D] KOG0656 G1/S-specific cyclin D
Length = 376
Score = 77.0 bits (188), Expect = 7e-14
Identities = 63/222 (28%), Positives = 108/222 (48%), Gaps = 25/222 (11%)
Query: 254 KEYEWEDLDEE--------DINDPFMVSEYVTDIFEYLHRLEMMTLPNRHE-----LFKH 300
+E +W+D EE + PF+V + D+F +++TL ++ E
Sbjct: 25 EEEKWDDEGEEVEENSSLSSSSSPFVVLQQ--DLF--WEDEDLVTLFSKEEEQGLSCLDD 80
Query: 301 ANIQQNRDILVNWMVKIHNKFGLLPETLYLALNIMDRFLCKELVQLEK---LQLVGTACL 357
+ +R V W+++++ +G LA+ +D+F+C +Q +K LQLV ACL
Sbjct: 81 VYLSTDRKEAVGWILRVNAHYGFSTLAAVLAITYLDKFICSYSLQRDKPWMLQLVSVACL 140
Query: 358 FIASKYEEVYSPSVKHF-AYETDGACDEEEIKEGEKFILKTLEFNLNYPNPMNF----LR 412
+A+K EE P + F ET + + I+ E IL TLE+ ++ P++F +R
Sbjct: 141 SLAAKVEETQVPLLLDFQVEETKYVFEAKTIQRMELLILSTLEWKMHLITPISFVDHIIR 200
Query: 413 RISKADDYDIQSRTLAKYLLEISIVDFKFIGILPSLCAAASM 454
R+ ++ LL I D +F+G LPS+ AAA+M
Sbjct: 201 RLGLKNNAHWDFLNKCHRLLLSVISDSRFVGYLPSVVAAATM 242
>At1g34460_1 [D] KOG0653 Cyclin B and related kinase-activating proteins
Length = 399
Score = 76.3 bits (186), Expect = 1e-13
Identities = 62/224 (27%), Positives = 98/224 (43%), Gaps = 27/224 (12%)
Query: 201 SLAPMPIDENANNSASSVELRAKQLQVEDSKKRPISTVVEQTLPKKFKVCEKGKEYEWED 260
+L P A N + ++ K L V+ K P+ + + + C + + D
Sbjct: 199 ALGPKSQPLAARNPEAQRAVQKKNLVVKQQTK-PVEVIETKRNAQSKAACGIVNKPKILD 257
Query: 261 LDEEDINDPFMVSEYVTDIFEYLHRLEMMTLPNRHELFKHANIQQN---RDILVNWMVKI 317
+DE D ++ EYV D++ + +E + P +++ H + N R IL++W++++
Sbjct: 258 IDESDKDNHVAAVEYVDDMYSFYKEVEKESQP---KMYMHIQTEMNEKMRAILIDWLLEV 314
Query: 318 HNKFGLLPETLYLALNIMDRFLCKELVQLEKLQLVGTACLFIASKYEEVYSPSVKHFAYE 377
H KF L ETLYL +NI+DRFL + V +LQ V Y
Sbjct: 315 HIKFELNLETLYLTVNIIDRFLYVKAVPKRELQ--------------------VNDLVYV 354
Query: 378 TDGACDEEEIKEGEKFILKTLEFNLNYPNPMNFLRRISKADDYD 421
TD A +I +K IL LE+ L P FL KA D
Sbjct: 355 TDNAYSSRQILVMKKAILGNLEWYLTIPTQYVFLFCFIKASISD 398
>ECU09g1030 [D] KOG0653 Cyclin B and related kinase-activating proteins
Length = 216
Score = 75.9 bits (185), Expect = 1e-13
Identities = 52/171 (30%), Positives = 90/171 (52%), Gaps = 10/171 (5%)
Query: 289 MTLPNRHELFKHANIQQNRDILVNWMVKIHNKFGLLPETLYLALNIMDRFLCKELVQLEK 348
+T NR + + +R LV W+ ++ + FG T A+ I+DR+ + LEK
Sbjct: 17 ITNVNRKNIKLTIHKSSHRRKLVQWLYEVTDDFGYSQVTFSTAVFILDRYTEARGLDLEK 76
Query: 349 LQLVGTACLFIASKYEEVYSPSVKHFAYETDGACDEEEIKEGEKFILKTLEFNLNYPNPM 408
QLVG + LF+++K EE + +V + + TDGAC +EI + E +L+ +FN+ P
Sbjct: 77 YQLVGISALFLSAKIEEKWCKAVDDYVHVTDGACSGKEILDKEIEMLEVFDFNMMLRLPH 136
Query: 409 NFL--RRISKADD-YDIQSRTLAKYLLEISIVDFKFIGILPSLCAAASMFL 456
+FL R + KA D Y ++ R EI F ++ I ++C ++ ++
Sbjct: 137 SFLQERYLEKASDKYTMKQRQ------EIFFCAFSYV-IEKNICGSSMYWI 180
>SPBC19F5.01c [D] KOG0653 Cyclin B and related kinase-activating proteins
Length = 359
Score = 71.6 bits (174), Expect = 3e-12
Identities = 44/143 (30%), Positives = 78/143 (53%), Gaps = 3/143 (2%)
Query: 272 VSEYVTDIFEYLHRLEMMTLPNRHELFKHANIQQN-RDILVNWMVKIHNKFGLLPETLYL 330
+ EY DI +L E L N H + ++ + R LVN++V+IHN F L +TL L
Sbjct: 93 LGEYQEDIIHHLITREKNFLLNVHLSNQQPELRWSMRPALVNFIVEIHNGFDLSIDTLPL 152
Query: 331 ALNIMDRFLCKELVQLEKLQLVGTACLFIASKYEEVYS--PSVKHFAYETDGACDEEEIK 388
++++MD ++ + +V + +QLV CL+IASK+ E P ++ E+
Sbjct: 153 SISLMDSYVSRRVVYCKHIQLVACVCLWIASKFHETEDRVPLLQELKLACKNIYAEDLFI 212
Query: 389 EGEKFILKTLEFNLNYPNPMNFL 411
E+ IL TL+++++ P P +++
Sbjct: 213 RMERHILDTLDWDISIPTPASYI 235
>Hs4502621 [D] KOG0654 G2/Mitotic-specific cyclin A
Length = 786
Score = 68.6 bits (166), Expect = 2e-11
Identities = 48/201 (23%), Positives = 99/201 (48%), Gaps = 6/201 (2%)
Query: 307 RDILVNWMVKIHNKFGLLPETLYLALNIMDRFLCKELVQLEKLQLVGTACLFIASKYEEV 366
R IL++W+V++ L+L + +DR+L + LV +LQL+G AC+ I +++
Sbjct: 310 RYILIDWLVEVATMNDFTSLCLHLTVECVDRYLRRRLVPRYRLQLLGIACMVICTRFISK 369
Query: 367 YSPSVKHFAYETDGACDEEEIKEGEKFILKTLEFNLNYPNPMNFLRRISKADDYDIQSRT 426
+++ + TD E++ I+ LE + P +++ + +++++
Sbjct: 370 EILTIREAVWLTDNTYKYEDLVRMMGEIVSALEGKIRVPTVVDYKEVLLTLVPVELRTQH 429
Query: 427 LAKYLLEISIVDFKFIGILPSLCAAASMFLSRKMLGKGQ-WDGNLIHYSGGYTKDELAPV 485
L +L E+S++ P+ AAA++ L+R G+ Q W L + G++ ++L P
Sbjct: 430 LCSFLCELSLLHTSLSAYAPARLAAAALLLARLTHGQTQPWTTQLWDLT-GFSYEDLIP- 487
Query: 486 CNMVMEYLVQPVVHDELFKKY 506
C + + + HD+ K Y
Sbjct: 488 CVLSLH---KKCFHDDAPKDY 505
>Hs4502617 [D] KOG0656 G1/S-specific cyclin D
Length = 289
Score = 68.2 bits (165), Expect = 3e-11
Identities = 44/152 (28%), Positives = 74/152 (47%), Gaps = 4/152 (2%)
Query: 307 RDILVNWMVKIHNKFGLLPETLYLALNIMDRFLCKELVQLEKLQLVGTACLFIASKYEEV 366
R ++ WM+++ + E LA+N +DRFL LQL+G C+F+ASK +E
Sbjct: 56 RRMVATWMLEVCEEQKCEEEVFPLAMNYLDRFLAGVPTPKSHLQLLGAVCMFLASKLKET 115
Query: 367 YSPSVKHFAYETDGACDEEEIKEGEKFILKTLEFNLNYPNPMNF----LRRISKADDYDI 422
+ + TD + +E+ E E +L L++NL P +F LR++ + +
Sbjct: 116 SPLTAEKLCIYTDNSIKPQELLEWELVVLGKLKWNLAAVTPHDFIEHILRKLPQQREKLS 175
Query: 423 QSRTLAKYLLEISIVDFKFIGILPSLCAAASM 454
R A+ + + DFKF PS+ A S+
Sbjct: 176 LIRKHAQTFIALCATDFKFAMYPPSMIATGSV 207
>At3g50070 [D] KOG0656 G1/S-specific cyclin D
Length = 361
Score = 66.6 bits (161), Expect = 9e-11
Identities = 58/220 (26%), Positives = 104/220 (46%), Gaps = 15/220 (6%)
Query: 250 CEKGKEY-EWEDLDEEDINDPFMVSEYVTDIFEYLHRLEMMTLPNRHELFKHANIQQN-- 306
CE+ E+ E DL +E + ++ ++D E+ TL ++ E + I +
Sbjct: 22 CEEESEFHEQVDLCDESVEKFPFLNLGLSDHDMLWDDDELSTLISKQEPCLYDEILDDEF 81
Query: 307 ----RDILVNWMVKIHNKFGLLPETLYLALNIMDRFLCKELVQLEK---LQLVGTACLFI 359
R+ ++W+ K+ + +G T LA+N DRF+ Q +K QL ACL +
Sbjct: 82 LVLCREKALDWIFKVKSHYGFNSLTALLAVNYFDRFITSRKFQTDKPWMSQLTALACLSL 141
Query: 360 ASKYEEVYSPSVKHF-AYETDGACDEEEIKEGEKFILKTLEFNLNYPNPMNF----LRRI 414
A+K EE+ P + F E + + I+ E +L TL++ ++ P++F +RR
Sbjct: 142 AAKVEEIRVPFLLDFQVEEARYVFEAKTIQRMELLVLSTLDWRMHPVTPISFFDHIIRRY 201
Query: 415 SKADDYDIQSRTLAKYLLEISIVDFKFIGILPSLCAAASM 454
S + ++ + + LL I D +F+ PS+ A A M
Sbjct: 202 SFKSHHQLEFLSRCESLLLSIIPDSRFLSFSPSVLATAIM 241
>Hs5802992 [D] KOG0653 Cyclin B and related kinase-activating proteins
Length = 377
Score = 65.1 bits (157), Expect = 3e-10
Identities = 35/107 (32%), Positives = 58/107 (53%), Gaps = 2/107 (1%)
Query: 307 RDILVNWMVKIHNKFGLLPETLYLALNIMDRFLCKELVQLEKLQLVGTACLFIASK--YE 364
RD ++ W+ K+ +F L PET LA +++DRFL + L + +C F+A+K E
Sbjct: 45 RDEVIQWLAKLKYQFNLYPETFALASSLLDRFLATVKAHPKYLSCIAISCFFLAAKTVEE 104
Query: 365 EVYSPSVKHFAYETDGACDEEEIKEGEKFILKTLEFNLNYPNPMNFL 411
+ P +K A ++ C EI E+ IL L ++L+ P++FL
Sbjct: 105 DERIPVLKVLARDSFCGCSSSEILRMERIILDKLNWDLHTATPLDFL 151
>7293153 [D] KOG0656 G1/S-specific cyclin D
Length = 481
Score = 64.3 bits (155), Expect = 4e-10
Identities = 49/178 (27%), Positives = 88/178 (48%), Gaps = 11/178 (6%)
Query: 307 RDILVNWMVKIHNKFGLLPETLYLALNIMDRFLCKELVQLEKLQLVGTACLFIASKYEE- 365
R I+ WM+++ + E + LALN MDRFL + V+ +LQ++ ACL +ASK E
Sbjct: 186 RKIVAEWMMEVCAEENCQEEVVLLALNYMDRFLSSKSVRKTQLQILAAACLLLASKLREP 245
Query: 366 -VYSPSVKHFAYETDGACDEEEIKEGEKFILKTLEFNLNYPNPMNFLRRI--------SK 416
+ SV TD + ++++ + E ++L L ++L+ P++FL +
Sbjct: 246 SCRALSVDLLVVYTDNSIYKDDLIKWELYVLSRLGWDLSSVTPLDFLELLMMRLPIGSKN 305
Query: 417 ADDYDI-QSRTLAKYLLEISIVDFKFIGILPSLCAAASMFLSRKMLGKGQWDGNLIHY 473
D +I + R A+ + ++ + KF S AA+S+ S L G+ +H+
Sbjct: 306 FPDINIGKVRGHAQAFISLAAKEHKFAKFSASTIAASSIAASMNGLKWHLRSGHNLHF 363
>Hs4502619 [D] KOG0656 G1/S-specific cyclin D
Length = 292
Score = 61.6 bits (148), Expect = 3e-09
Identities = 47/181 (25%), Positives = 83/181 (44%), Gaps = 5/181 (2%)
Query: 307 RDILVNWMVKIHNKFGLLPETLYLALNIMDRFLCKELVQLEKLQLVGTACLFIASKYEEV 366
R +L WM+++ + E LA+N +DR+L + +LQL+G C+ +ASK E
Sbjct: 57 RKMLAYWMLEVCEEQRCEEEVFPLAMNYLDRYLSCVPTRKAQLQLLGAVCMLLASKLRET 116
Query: 367 YSPSVKHFAYETDGACDEEEIKEGEKFILKTLEFNLNYPNPMNF----LRRISKADDYDI 422
+++ TD A ++++ E +L L+++L +F L R+S D
Sbjct: 117 TPLTIEKLCIYTDHAVSPRQLRDWEVLVLGKLKWDLAAVIAHDFLAFILHRLSLPRDRQA 176
Query: 423 QSRTLAKYLLEISIVDFKFIGILPSLCAAASMFLSRKMLGKGQWDGN-LIHYSGGYTKDE 481
+ A+ L + D+ F PS+ A S+ + + LG G+ L G T E
Sbjct: 177 LVKKHAQTFLALCATDYTFAMYPPSMIATGSIGAAVQGLGACSMSGDELTELLAGITGTE 236
Query: 482 L 482
+
Sbjct: 237 V 237
>At5g67260 [D] KOG0656 G1/S-specific cyclin D
Length = 367
Score = 60.5 bits (145), Expect = 6e-09
Identities = 59/231 (25%), Positives = 99/231 (42%), Gaps = 24/231 (10%)
Query: 250 CEKGKEYEWEDLDEEDINDPFMVSEYVTDIFEYLHRLEMM----------------TLPN 293
CE+ + +DLD++ D S+ F++L L+M T P
Sbjct: 23 CEEETGFVEDDLDDDGDLDFLEKSDESVVKFQFLPLLDMFLWDDDEILSLISKENETNPC 82
Query: 294 RHELFKHANIQQNRDILVNWMVKIHNKFGLLPETLYLALNIMDRFLCKELVQLEK---LQ 350
E + R ++W++++ + +G T LA+N DRF+ +Q +K Q
Sbjct: 83 FGEQILDGFLVSCRKEALDWVLRVKSHYGFTSLTAILAVNYFDRFMTSIKLQTDKPWMSQ 142
Query: 351 LVGTACLFIASKYEEVYSPSVKHFAYETDGACDE-EEIKEGEKFILKTLEFNLNYPNPMN 409
LV A L +A+K EE+ P + E E + I+ E IL TL++ ++ P++
Sbjct: 143 LVAVASLSLAAKVEEIQVPLLLDLQVEEARYLFEAKTIQRMELLILSTLQWRMHPVTPIS 202
Query: 410 F----LRRISKADDYDIQSRTLAKYLLEISIVDFKFIGILPSLCAAASMFL 456
F +RR + + LL I D +F+ PS+ A A M L
Sbjct: 203 FFDHIIRRFGSKWHQQLDFCRKCERLLISVIADTRFMRYFPSVLATAIMIL 253
>At1g70210 [D] KOG0656 G1/S-specific cyclin D
Length = 339
Score = 60.1 bits (144), Expect = 8e-09
Identities = 48/158 (30%), Positives = 78/158 (48%), Gaps = 12/158 (7%)
Query: 307 RDILVNWMVKIHNKFGLLPETLYLALNIMDRFL-CKELVQLE--KLQLVGTACLFIASKY 363
R+ V W++K+ + P T YLA+N MDRFL + L + +QL+ ACL +A+K
Sbjct: 82 REDSVAWILKVQAYYNFQPLTAYLAVNYMDRFLYARRLPETSGWPMQLLAVACLSLAAKM 141
Query: 364 EEVYSPSVKHFAYETDGA---CDEEEIKEGEKFILKTLEFNLNYPNPMNFLRRIS-KADD 419
EE+ PS+ F ++ G + + IK E +L L++ L P +F+ + K D
Sbjct: 142 EEILVPSL--FDFQVAGVKYLFEAKTIKRMELLVLSVLDWRLRSVTPFDFISFFAYKIDP 199
Query: 420 YDIQSRTLAKYLLEISIVDFK---FIGILPSLCAAASM 454
+ EI + + K F+ PS AAA++
Sbjct: 200 SGTFLGFFISHATEIILSNIKEASFLEYWPSSIAAAAI 237
>7292370 [D] KOG0654 G2/Mitotic-specific cyclin A
Length = 386
Score = 56.6 bits (135), Expect = 9e-08
Identities = 66/274 (24%), Positives = 111/274 (40%), Gaps = 39/274 (14%)
Query: 262 DEEDINDPFMVSEYVTDIFEYLHRLEMMTLPNRHELFKHANIQQNRDILVNWMVKIHNKF 321
D E + +++Y DIF + E+ +R LF + R ++ + +
Sbjct: 26 DVERLAKTHWLTDYARDIFLTMREQEL----SRRPLFYLSPQLNERRRMLQLLKLATSAH 81
Query: 322 GLLPETLYLALNIMDRFLCKELVQLEKLQLVGTACLFIASKYE--EVYSPSVKHFAYETD 379
L L+LA+ MDRF+ ++ +KL LV CL IA++ E + + P
Sbjct: 82 KLSRCALHLAVYYMDRFVDYYKIRPDKLLLVAITCLHIAAQIENTDAFIPRYSEMNRLVK 141
Query: 380 GACDEEEIKEGEKFILKTLEFNLNYPNPMNFL--------------RRISKADDYDIQSR 425
A E K E+ IL L F L P +F+ I D+Y+
Sbjct: 142 NAYTAFEYKAVERKILCFLNFELIRPTTASFVELFACSFLTRSDFKNYIEMLDEYERNHH 201
Query: 426 T---------------LAKYLL---EISIVDFKFIGILPSLCAAASMFLSRKMLGKGQWD 467
T LA+ LL + ++ +F LPSL AAA + R++ G +W
Sbjct: 202 TQPYQRYISFEEMLSILAQLLLRMADYTLYISRFANDLPSLLAAACIAAVRQVSGVRRWS 261
Query: 468 GNLIHYSGGYTKDELAPVCNMVMEYLVQPVVHDE 501
L+ + YT+ + P N++ +Y V+ +
Sbjct: 262 EYLVGLT-SYTEANVEPYMNVLTDYYYYHVIQTD 294
>At5g02110 [D] KOG0656 G1/S-specific cyclin D
Length = 341
Score = 56.2 bits (134), Expect = 1e-07
Identities = 46/170 (27%), Positives = 79/170 (46%), Gaps = 12/170 (7%)
Query: 296 ELFKHANIQQNRDILVNWMVKIHNKFGLLPETLYLALNIMDRFL----CKELVQLEKLQL 351
E F + R W+++ ++ L ET++ A N DRF+ C E ++L
Sbjct: 67 EFFVSKKLTDYRFHAFQWLIQTRSRLNLSYETVFSAANCFDRFVYMTCCDEWTNW-MVEL 125
Query: 352 VGTACLFIASKYEEVYSPSVKHFAYE-TDGACDEEEIKEGEKFILKTLEFNLN----YPN 406
V L IASK+ EV +P ++ E + + E ILK LE+ +N Y
Sbjct: 126 VAVTSLSIASKFNEVTTPLLEELEMEGLTHMFHVNTVAQMELIILKALEWRVNAVTSYTF 185
Query: 407 PMNFLRRISKADDYDIQSRTLAKYLLEISIVDFKFIGILPSLCAAASMFL 456
+ +I D+ I +R + +LL++ I D K + PS+ A A++++
Sbjct: 186 SQTLVSKIGMVGDHMIMNR-ITNHLLDV-ICDLKMLQYPPSVVATAAIWI 233
>Hs13376318 [D] KOG0653 Cyclin B and related kinase-activating proteins
Length = 155
Score = 55.8 bits (133), Expect = 2e-07
Identities = 28/78 (35%), Positives = 43/78 (54%)
Query: 292 PNRHELFKHANIQQNRDILVNWMVKIHNKFGLLPETLYLALNIMDRFLCKELVQLEKLQL 351
P E +Q R+ + ++ GL +TLYLA++++D +L V+L +LQL
Sbjct: 63 PGLEEALSALGLQGEREYAGDIFAEVMEYLGLAGDTLYLAVHLLDSYLSAGRVRLHRLQL 122
Query: 352 VGTACLFIASKYEEVYSP 369
+G ACLF+A K EE P
Sbjct: 123 LGVACLFVACKMEECVLP 140
>CE21610 [D] KOG0656 G1/S-specific cyclin D
Length = 405
Score = 52.8 bits (125), Expect = 1e-06
Identities = 30/124 (24%), Positives = 60/124 (48%), Gaps = 8/124 (6%)
Query: 292 PNRHELFKHANIQQN-----RDILVNWMVKIHNKFGLLPETLYLALNIMDRFLCKELVQL 346
PN H +Q+N R+ ++W+ + + + LA++++DRF+ + +
Sbjct: 88 PNYHYF---TGVQENITPFHREQAIDWIYDVAKEENCDGDVFLLAVSLIDRFMSVQNILK 144
Query: 347 EKLQLVGTACLFIASKYEEVYSPSVKHFAYETDGACDEEEIKEGEKFILKTLEFNLNYPN 406
+Q++ LFIASK + + + AY +D +C + I + E I+ TL++ P
Sbjct: 145 HDIQMIAGVALFIASKLKAPHPMTASKIAYYSDNSCPIDMILQWELLIVTTLQWETESPT 204
Query: 407 PMNF 410
+F
Sbjct: 205 AFSF 208
>Hs4757936 [D] KOG0653 Cyclin B and related kinase-activating proteins
Length = 344
Score = 50.4 bits (119), Expect = 7e-06
Identities = 33/107 (30%), Positives = 50/107 (45%), Gaps = 2/107 (1%)
Query: 307 RDILVNWMVKIHNKFGLLPETLYLALNIMDRFLCKELVQLEKLQLVGTACLFIASKY--E 364
R+ V + + N FG ET LA+NI+DRFL V+ + L +G +A++ E
Sbjct: 56 RNAKVEDLRSLANFFGSCTETFVLAVNILDRFLALMKVKPKHLSCIGVCSFLLAARIVEE 115
Query: 365 EVYSPSVKHFAYETDGACDEEEIKEGEKFILKTLEFNLNYPNPMNFL 411
+ PS + C +IK EK I + L + L +NFL
Sbjct: 116 DCNIPSTHDVIRISQCKCTASDIKRMEKIISEKLHYELEATTALNFL 162
>Hs20541478 [D] KOG0653 Cyclin B and related kinase-activating proteins
Length = 153
Score = 50.4 bits (119), Expect = 7e-06
Identities = 37/123 (30%), Positives = 59/123 (47%), Gaps = 12/123 (9%)
Query: 259 EDLDEEDINDPFMVSEYVTDIFEYLHRLEMMTLPNRHELFKHANIQQ-NRDILVNWMVKI 317
ED+D+ D++DPF S Y +I Y++ E K +I R ILV+W+ K+
Sbjct: 39 EDIDK-DLSDPFFNSIYTKEISSYMNLREE----------KQTDINSVMRVILVDWLGKM 87
Query: 318 HNKFGLLPETLYLALNIMDRFLCKELVQLEKLQLVGTACLFIASKYEEVYSPSVKHFAYE 377
F + ETL L L + + + + + + LQL+G +A+K+EE V Y
Sbjct: 88 QISFEMTQETLSLVLKPVYHYFMEVVCKKDGLQLLGPTAFLMAAKFEEPCPSFVDDLLYL 147
Query: 378 TDG 380
G
Sbjct: 148 CGG 150
Database: KOG eukaryal database 04/03
Posted date: Apr 14, 2003 1:07 PM
Number of letters in database: 30,389,216
Number of sequences in database: 60,738
Lambda K H
0.315 0.132 0.377
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 32,784,839
Number of Sequences: 60738
Number of extensions: 1461118
Number of successful extensions: 4846
Number of sequences better than 1.0e-05: 73
Number of HSP's better than 0.0 without gapping: 63
Number of HSP's successfully gapped in prelim test: 10
Number of HSP's that attempted gapping in prelim test: 4704
Number of HSP's gapped (non-prelim): 76
length of query: 539
length of database: 30,389,216
effective HSP length: 111
effective length of query: 428
effective length of database: 23,647,298
effective search space: 10121043544
effective search space used: 10121043544
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.6 bits)