ORF STATUS Function Best COG Functional category Pathways and functional systems
r_klactIV3887 good D KOG0653 Cell cycle control, cell division, chromosome partitioning Cyclin B and related kinase-activating proteins
Only best alignment is shown:
BLASTP 2.2.3 [May-13-2002]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= r_klactIV3887 1317351 1316128 -408
(408 letters)
Database: KOG eukaryal database 04/03
60,738 sequences; 30,389,216 total letters
Searching..................................................done
Color Key for Alignment Scores: 
Score E
Sequences producing significant alignments: (bits) Value
YPR120c [D] KOG0653 Cyclin B and related kinase-activating proteins 288 8e-78
YGR109c [D] KOG0653 Cyclin B and related kinase-activating proteins 246 6e-65
YDL155w [D] KOG0653 Cyclin B and related kinase-activating proteins 182 1e-45
SPBC582.03 [D] KOG0653 Cyclin B and related kinase-activating pr... 179 7e-45
YGR108w [D] KOG0653 Cyclin B and related kinase-activating proteins 177 2e-44
YPR119w [D] KOG0653 Cyclin B and related kinase-activating proteins 172 6e-43
YLR210w [D] KOG0653 Cyclin B and related kinase-activating proteins 172 1e-42
Hs4757930 [D] KOG0653 Cyclin B and related kinase-activating pro... 166 4e-41
SPAPB2B4.03 [D] KOG0653 Cyclin B and related kinase-activating p... 159 9e-39
At1g77390 [D] KOG0654 G2/Mitotic-specific cyclin A 145 1e-34
Hs14327896 [D] KOG0653 Cyclin B and related kinase-activating pr... 142 9e-34
At1g20610 [D] KOG0653 Cyclin B and related kinase-activating pro... 138 1e-32
ECU08g0260 [D] KOG0653 Cyclin B and related kinase-activating pr... 137 2e-32
SPCC4E9.02 [D] KOG0653 Cyclin B and related kinase-activating pr... 137 3e-32
At4g35620 [D] KOG0653 Cyclin B and related kinase-activating pro... 137 4e-32
At5g25380 [D] KOG0654 G2/Mitotic-specific cyclin A 134 2e-31
At5g43080 [D] KOG0654 G2/Mitotic-specific cyclin A 132 7e-31
At1g80370 [D] KOG0654 G2/Mitotic-specific cyclin A 132 9e-31
At2g17620 [D] KOG0653 Cyclin B and related kinase-activating pro... 131 2e-30
At1g47210 [D] KOG0654 G2/Mitotic-specific cyclin A 130 3e-30
At1g44110 [D] KOG0654 G2/Mitotic-specific cyclin A 130 3e-30
At1g15570 [D] KOG0654 G2/Mitotic-specific cyclin A 129 1e-29
At5g06150 [D] KOG0653 Cyclin B and related kinase-activating pro... 128 1e-29
At3g11520 [D] KOG0653 Cyclin B and related kinase-activating pro... 128 2e-29
At1g47230 [D] KOG0654 G2/Mitotic-specific cyclin A 128 2e-29
7291478 [D] KOG0653 Cyclin B and related kinase-activating proteins 125 9e-29
Hs14719420_2 [D] KOG0653 Cyclin B and related kinase-activating ... 124 2e-28
At1g76310 [D] KOG0653 Cyclin B and related kinase-activating pro... 124 3e-28
At1g47220 [D] KOG0654 G2/Mitotic-specific cyclin A 122 1e-27
At2g26760 [D] KOG0653 Cyclin B and related kinase-activating pro... 121 2e-27
SPBC16E9.17c [D] KOG0653 Cyclin B and related kinase-activating ... 119 6e-27
At5g11300 [D] KOG0654 G2/Mitotic-specific cyclin A 119 8e-27
Hs4502611 [D] KOG0654 G2/Mitotic-specific cyclin A 118 1e-26
CE06570 [D] KOG0653 Cyclin B and related kinase-activating proteins 114 3e-25
CE28122 [D] KOG0653 Cyclin B and related kinase-activating proteins 113 6e-25
At4g37490 [D] KOG0653 Cyclin B and related kinase-activating pro... 108 1e-23
Hs4502613 [D] KOG0654 G2/Mitotic-specific cyclin A 107 2e-23
CE23835 [D] KOG0653 Cyclin B and related kinase-activating proteins 107 4e-23
At1g16330 [D] KOG0653 Cyclin B and related kinase-activating pro... 106 5e-23
CE27776 [D] KOG0653 Cyclin B and related kinase-activating proteins 99 9e-21
CE13315 [D] KOG0653 Cyclin B and related kinase-activating proteins 99 9e-21
Hs16306525_2 [D] KOG0653 Cyclin B and related kinase-activating ... 98 3e-20
7294661 [D] KOG0654 G2/Mitotic-specific cyclin A 92 1e-18
Hs17318567 [D] KOG0655 G1/S-specific cyclin E 91 3e-18
Hs17318565 [D] KOG0655 G1/S-specific cyclin E 91 3e-18
Hs17318561 [D] KOG0655 G1/S-specific cyclin E 89 2e-17
Hs17318559 [D] KOG0655 G1/S-specific cyclin E 89 2e-17
7298245 [D] KOG0655 G1/S-specific cyclin E 87 4e-17
Hs22048740 [D] KOG0655 G1/S-specific cyclin E 83 8e-16
At1g20590 [D] KOG0653 Cyclin B and related kinase-activating pro... 83 8e-16
CE03820 [D] KOG0654 G2/Mitotic-specific cyclin A 82 2e-15
SPBC19F5.01c [D] KOG0653 Cyclin B and related kinase-activating ... 80 5e-15
At1g34460_1 [D] KOG0653 Cyclin B and related kinase-activating p... 80 7e-15
Hs16950655 [D] KOG0656 G1/S-specific cyclin D 77 5e-14
HsM4502615 [D] KOG0656 G1/S-specific cyclin D 75 2e-13
CE24832 [D] KOG0655 G1/S-specific cyclin E 71 3e-12
Hs4502621 [D] KOG0654 G2/Mitotic-specific cyclin A 67 5e-11
7293153 [D] KOG0656 G1/S-specific cyclin D 67 5e-11
Hs4502617 [D] KOG0656 G1/S-specific cyclin D 65 2e-10
Hs5802992 [D] KOG0653 Cyclin B and related kinase-activating pro... 60 6e-09
ECU09g1030 [D] KOG0653 Cyclin B and related kinase-activating pr... 60 6e-09
At5g65420 [D] KOG0656 G1/S-specific cyclin D 60 8e-09
Hs4502619 [D] KOG0656 G1/S-specific cyclin D 59 2e-08
At1g70210 [D] KOG0656 G1/S-specific cyclin D 57 4e-08
YAL040c [D] KOG0653 Cyclin B and related kinase-activating proteins 56 1e-07
CE09256 [D] KOG0654 G2/Mitotic-specific cyclin A 56 1e-07
At5g67260 [D] KOG0656 G1/S-specific cyclin D 55 2e-07
Hs4757936 [D] KOG0653 Cyclin B and related kinase-activating pro... 55 2e-07
CE21610 [D] KOG0656 G1/S-specific cyclin D 55 2e-07
At5g10440 [D] KOG0656 G1/S-specific cyclin D 55 2e-07
At4g37630 [D] KOG0656 G1/S-specific cyclin D 54 3e-07
At4g34160 [D] KOG0656 G1/S-specific cyclin D 54 3e-07
CE20913 [D] KOG0654 G2/Mitotic-specific cyclin A 54 5e-07
7292370 [D] KOG0654 G2/Mitotic-specific cyclin A 53 7e-07
Hs20541478 [D] KOG0653 Cyclin B and related kinase-activating pr... 53 9e-07
At3g50070 [D] KOG0656 G1/S-specific cyclin D 52 1e-06
At2g22490 [D] KOG0656 G1/S-specific cyclin D 52 2e-06
At5g02110 [D] KOG0656 G1/S-specific cyclin D 50 5e-06
>YPR120c [D] KOG0653 Cyclin B and related kinase-activating proteins
Length = 435
Score = 288 bits (738), Expect = 8e-78
Identities = 163/394 (41%), Positives = 240/394 (60%), Gaps = 11/394 (2%)
Query: 4 RTRSSWSVSDAEAMEKSSHQRKRVALSEQPLHDNKLKSSVGSLRNSQVDEGKNKIYGNSS 63
+ + + S +D+ + ++ + R AL++ P+++N L + + S+ + + + N
Sbjct: 34 QNKRALSKNDSSSKQQVQDSKPRRALTDVPVNNNPLSQNKRIVAGSKAAKVRRE--ENIR 91
Query: 64 QTTSSVSLKRQIYRDD---DDEEQKSDVRSDDDI--LEPRKSHKXXXXXXXXXXXXXXDS 118
S+V KRQIY D + EE++ + DDD + +K D
Sbjct: 92 PIVSAVQ-KRQIYNDRTAAEQEEEEEEEGEDDDAASIVNKKRRIDAEGVSEIVGWQDLDY 150
Query: 119 QDKEDVTMCYDYSDDIFDHLYTRQFETTPKINYLKDKNYEFYLRPTMRSILVDWIIEVHC 178
+K+D M +YS +IF LY R+ ET P NYL DK ++YLRP+MR+ILVDW++EVH
Sbjct: 151 VEKDDTAMVAEYSAEIFAFLYRRELETLPSHNYLLDKTSKYYLRPSMRTILVDWLVEVHE 210
Query: 179 KFQLLPETLYLSINLMDRYLSFNKVTLPKLQLIAITSLLIAAKFEEVNLPKLSNYSYITD 238
KFQ PETL+LSINLMDR+L+ NKVT+ KLQL+A+TSL IAAKFEEVNLPKL+ Y+YITD
Sbjct: 211 KFQCYPETLFLSINLMDRFLAKNKVTMNKLQLLAVTSLFIAAKFEEVNLPKLAEYAYITD 270
Query: 239 NAYSNDEIKQAEFVILNKLEYNIGWPNPLNFLRRISRCDEYDSITRTLGKCLIGYMISCP 298
A S ++IK AE +L LE+NIGWPNPLNFLRRIS+ D+YD + R +GK ++ Y C
Sbjct: 271 GAASKNDIKNAEMFMLTSLEFNIGWPNPLNFLRRISKADDYDPVNRNIGKFILEYAYCCH 330
Query: 299 HFIDVVPSKIASVAMFTAQRIVHEDFQ--WDELWDYYSCFSFKDNEIELKELSQILINDI 356
FI + PS ++++AM+ A+R+ + + W+ +YS ++ + L L+ DI
Sbjct: 331 QFIHLPPSTVSAMAMYIARRMTNRNKNELWNGTLQHYSGGIDPIHDEAFQSLCIDLVKDI 390
Query: 357 AKPTTQLNALIHKYKKIGTWNKIHDWCLKHCTYE 390
A T L++LI KYKK + ++ K CT E
Sbjct: 391 ASSKTHLDSLILKYKK-PRYGSVYFQTFKWCTSE 423
>YGR109c [D] KOG0653 Cyclin B and related kinase-activating proteins
Length = 380
Score = 246 bits (627), Expect = 6e-65
Identities = 137/360 (38%), Positives = 212/360 (58%), Gaps = 22/360 (6%)
Query: 27 VALSEQPLHDNKLKSSVGSLRNSQVDEGKNKIYGNSSQTTSSVSLKRQIYRDDDDEEQKS 86
+ L+ ++ K+ S V S + + + K+ +S+ + KRQ+ D D +
Sbjct: 36 INLTPHSTNEKKVLSEVNSNKIDSLQLPRGKLQRDSTHLEKT--RKRQLSNDSTDPIEPK 93
Query: 87 DVRSDDDILEPRKSHKXXXXXXXXXXXXXXDSQDKEDVTMCYDYSDDIFDHLYTRQFETT 146
V+ K H+ DS + +D M +Y+D IF HLY ++ +
Sbjct: 94 TVKKI-------KCHQWKNL----------DSIEMDDPFMVAEYTDSIFSHLYEKEIQML 136
Query: 147 PKINYLKDKNYEFYLRPTMRSILVDWIIEVHCKFQLLPETLYLSINLMDRYLSFNKVTLP 206
P NYL D ++L+ +MR++L+DW++EVH KF LPETL+L+INL+DR+LS N V L
Sbjct: 137 PTHNYLMDTQSPYHLKSSMRALLIDWLVEVHEKFHCLPETLFLAINLLDRFLSQNVVKLN 196
Query: 207 KLQLIAITSLLIAAKFEEVNLPKLSNYSYITDNAYSNDEIKQAEFVILNKLEYNIGWPNP 266
KLQL+ IT L IA KFEEV LPK++N++Y+TD A + + I++AE +L+ L YNI PNP
Sbjct: 197 KLQLLCITCLFIACKFEEVKLPKITNFAYVTDGAATVEGIRKAELFVLSSLGYNISLPNP 256
Query: 267 LNFLRRISRCDEYDSITRTLGKCLIGYMISCPHFIDVVPSKIASVAMFTAQRIVHEDFQW 326
LNF+RRIS+ D Y TR + K ++ Y I C FI + PS +A+++M+ A++I +E+ +W
Sbjct: 257 LNFIRRISKADNYCIETRNMAKFIMEYSICCNKFIHLKPSYLAAMSMYIARKIKNENSKW 316
Query: 327 DELWDYYSCFSFKDNEIELKELSQILINDIAKPTTQLNALIHKYKKIG---TWNKIHDWC 383
DE + +YS +++ K+ L+ DIA P T L++L KYKK + K+ DWC
Sbjct: 317 DETFIHYSGGIDIESDPAFKDFISELVEDIAVPDTNLDSLRLKYKKPKHGMVYFKVFDWC 376
>YDL155w [D] KOG0653 Cyclin B and related kinase-activating proteins
Length = 427
Score = 182 bits (461), Expect = 1e-45
Identities = 104/255 (40%), Positives = 157/255 (60%), Gaps = 10/255 (3%)
Query: 117 DSQDKEDVTMCYDYSDDIFDHLYTRQFETTPKIN-YLKDKNYEFYLRPTMRSILVDWIIE 175
+ D DV M + S++IF+ Y R+ E K N Y DK E LR + RS L+DWI++
Sbjct: 155 NDDDVYDVVMVAELSNEIFE--YMRKLEDLYKPNPYYMDKQPE--LRWSFRSTLIDWIVQ 210
Query: 176 VHCKFQLLPETLYLSINLMDRYLSFNKVTLPKLQLIAITSLLIAAKFEEVNLPKLSNYSY 235
VH KFQLLPETLYL IN++DRYL V + K QL+ SL IAAK+EE+N P + ++ Y
Sbjct: 211 VHEKFQLLPETLYLCINIIDRYLCKEVVPVNKFQLVGAASLFIAAKYEEINCPTIKDFVY 270
Query: 236 ITDNAYSNDEIKQAEFVILNKLEYNIGWPNPLNFLRRISRCDEYDSITRTLGKCLIGYMI 295
+++N YS +++ AE ILN LE+ +GWP P++FLRRIS+ D+Y+ TRTL K L+ I
Sbjct: 271 MSENCYSRNDLLDAERTILNGLEFELGWPGPMSFLRRISKADDYEHDTRTLAKYLLESTI 330
Query: 296 SCPHFIDVVPSKIASVAMFTAQRIVHEDFQWDELWDYYSCFSFKDNEIELKELSQILIND 355
+ PS +A+ A F ++ I+ ++ QW YYS ++ + ++ L+ I++ +
Sbjct: 331 MDHRLVSAQPSWLAAGAYFLSKIILGQN-QWSLAHVYYSNYT----QEQILPLATIILEN 385
Query: 356 IAKPTTQLNALIHKY 370
+ + NA+ KY
Sbjct: 386 CRYASKRHNAIWRKY 400
>SPBC582.03 [D] KOG0653 Cyclin B and related kinase-activating proteins
Length = 482
Score = 179 bits (454), Expect = 7e-45
Identities = 124/383 (32%), Positives = 195/383 (50%), Gaps = 24/383 (6%)
Query: 10 SVSDAEAMEKSS--HQRKRVALSEQPLHDNKLKSSVGSL-RNSQVDEGKNKIYGNSSQTT 66
SVS A+E+ S S++ + SSV SL ++ +G +
Sbjct: 89 SVSTRRALEEKSIIPATDDEPASKKRRQPSVFNSSVPSLPQHLSTKSHSVSTHGVDAFHK 148
Query: 67 SSVSLKRQIYRDDDDEEQKSDVRSDDDILEPRKSHKXXXXXXXXXXXXXXDSQDKEDVTM 126
++ +++ +D D+ D+ K H+ D++D D M
Sbjct: 149 DQATIPKKLKKDVDERVVSKDIP---------KLHRDSVESPESQDWDDLDAEDWADPLM 199
Query: 127 CYDYSDDIFDHLYTRQFETTPKINYLKDKNYEFYLRPTMRSILVDWIIEVHCKFQLLPET 186
+Y DIF++L + ET P Y+ D+ E + MR IL DW+IEVH +F+LLPET
Sbjct: 200 VSEYVVDIFEYLNELEIETMPSPTYM-DRQKELAWK--MRGILTDWLIEVHSRFRLLPET 256
Query: 187 LYLSINLMDRYLSFNKVTLPKLQLIAITSLLIAAKFEEVNLPKLSNYSYITDNAYSNDEI 246
L+L++N++DR+LS +L KLQL+ I +L IA+K+EEV P + N+ Y+ D Y +EI
Sbjct: 257 LFLAVNIIDRFLSLRVCSLNKLQLVGIAALFIASKYEEVMCPSVQNFVYMADGGYDEEEI 316
Query: 247 KQAEFVILNKLEYNIGWPNPLNFLRRISRCDEYDSITRTLGKCLIGYMISCPHFIDVVPS 306
QAE IL LE+N+ +PNP+NFLRRIS+ D YD TRT+ K L+ + + PS
Sbjct: 317 LQAERYILRVLEFNLAYPNPMNFLRRISKADFYDIQTRTVAKYLVEIGLLDHKLLPYPPS 376
Query: 307 KIASVAMFTAQRIVHEDFQWDELWDYYSCFSFKDNEIELKELSQILINDIAKPTTQLNAL 366
+ + AM+ A+ ++ W+ +YS + E +L + + +IN + KP Q A
Sbjct: 377 QQCAAAMYLAREMLGRG-PWNRNLVHYSGY----EEYQLISVVKKMINYLQKP-VQHEAF 430
Query: 367 IHKY---KKIGTWNKIHDWCLKH 386
KY K + + DW K+
Sbjct: 431 FKKYASKKFMKASLFVRDWIKKN 453
>YGR108w [D] KOG0653 Cyclin B and related kinase-activating proteins
Length = 471
Score = 177 bits (450), Expect = 2e-44
Identities = 111/317 (35%), Positives = 172/317 (54%), Gaps = 20/317 (6%)
Query: 21 SHQRKRVALSEQPLHDNKLKSSVGSLRNSQVDEGKNKIYGNSSQTTSSVSLKRQIYRDDD 80
S Q K+ ++ H N S L IY + ++ + +++I R+D
Sbjct: 109 SEQEKQQCSNDDSFHTNSTALSCNRL-----------IYSENKSISTQMEWQKKIMREDS 157
Query: 81 DEEQKSDVRSDDDILEPRKSHKXXXXXXXXXXXX--XXDSQDKEDVTMCYDYSDDIFDHL 138
+++ + D + K H+ D +D +D M + +DIFD+L
Sbjct: 158 KKKRPISTLVEQDDQKKFKLHELTTEEEVLEEYEWDDLDEEDCDDPLMVSEEVNDIFDYL 217
Query: 139 YTRQFETTP-KINYLKDKNYEFYLRPTMRSILVDWIIEVHCKFQLLPETLYLSINLMDRY 197
+ + T P K N K KN + R ILV+WII++H KF LLPETLYL+IN+MDR+
Sbjct: 218 HHLEIITLPNKANLYKHKNIK-----QNRDILVNWIIKIHNKFGLLPETLYLAINIMDRF 272
Query: 198 LSFNKVTLPKLQLIAITSLLIAAKFEEVNLPKLSNYSYITDNAYSNDEIKQAEFVILNKL 257
L V L +LQL+ + L IA+K+EE+ P + +++Y TD A S ++IK+ E IL KL
Sbjct: 273 LCEEVVQLNRLQLVGTSCLFIASKYEEIYSPSIKHFAYETDGACSVEDIKEGERFILEKL 332
Query: 258 EYNIGWPNPLNFLRRISRCDEYDSITRTLGKCLIGYMISCPHFIDVVPSKIASVAMFTAQ 317
++ I + NP+NFLRRIS+ D+YD +RTL K L+ I FI ++PS AS AMF ++
Sbjct: 333 DFQISFANPMNFLRRISKADDYDIQSRTLAKFLMEISIVDFKFIGILPSLCASAAMFLSR 392
Query: 318 RIVHEDFQWDELWDYYS 334
+++ + WD +YS
Sbjct: 393 KMLGKG-TWDGNLIHYS 408
>YPR119w [D] KOG0653 Cyclin B and related kinase-activating proteins
Length = 491
Score = 172 bits (437), Expect = 6e-43
Identities = 96/243 (39%), Positives = 152/243 (62%), Gaps = 8/243 (3%)
Query: 117 DSQDKEDVTMCYDYSDDIFDHLYTRQFETTPKINYLKDKNYEFYLRPTMRSILVDWIIEV 176
D++D D M +Y +DIF++L+ + T PK K+ Y+ R ILV+W++++
Sbjct: 216 DAEDVNDPFMVSEYVNDIFEYLHQLEVITLPK----KEDLYQHRNIHQNRDILVNWLVKI 271
Query: 177 HCKFQLLPETLYLSINLMDRYLSFNKVTLPKLQLIAITSLLIAAKFEEVNLPKLSNYSYI 236
H KF LLPETLYL+IN+MDR+L V L KLQL+ + L IA+K+EEV P + +++
Sbjct: 272 HNKFGLLPETLYLAINIMDRFLGKELVQLDKLQLVGTSCLFIASKYEEVYSPSIKHFASE 331
Query: 237 TDNAYSNDEIKQAEFVILNKLEYNIGWPNPLNFLRRISRCDEYDSITRTLGKCLIGYMIS 296
TD A + DEIK+ E IL L++N+ +PNP+NFLRRIS+ D+YD +RTL K L+ +
Sbjct: 332 TDGACTEDEIKEGEKFILKTLKFNLNYPNPMNFLRRISKADDYDIQSRTLAKFLLEISLV 391
Query: 297 CPHFIDVVPSKIASVAMFTAQRIVHEDFQWDELWDYYSCFSFKDNEIELKELSQILINDI 356
FI ++PS A+ AMF +++++ + +WD +YS K+ EL + ++++ +
Sbjct: 392 DFRFIGILPSLCAAAAMFMSRKMLGKG-KWDGNLIHYSGGYTKE---ELAPVCHMIMDYL 447
Query: 357 AKP 359
P
Sbjct: 448 VSP 450
>YLR210w [D] KOG0653 Cyclin B and related kinase-activating proteins
Length = 460
Score = 172 bits (435), Expect = 1e-42
Identities = 100/305 (32%), Positives = 168/305 (54%), Gaps = 16/305 (5%)
Query: 74 QIYRDDDDEEQ---KSDVRSDDDILEPRKSHKXXXXXXXXXXXXXXD-----SQDKEDVT 125
++Y D D E Q + DV S + L P + + D DV
Sbjct: 143 EVYEDFDGEMQDVIEEDVDSQIEPLSPINNDEIQTELDRAFEKYFRSVPNPLDDDTHDVV 202
Query: 126 MCYDYSDDIFDHLYTRQFETTPKINYLKDKNYEFYLRPTMRSILVDWIIEVHCKFQLLPE 185
M +Y+ DIF +L + + P Y+++ + L R ++DW++++H +FQLLPE
Sbjct: 203 MVVEYASDIFYYLRELEVKYRPNPYYMQN---QVELTWPFRRTMIDWLVQLHFRFQLLPE 259
Query: 186 TLYLSINLMDRYLSFNKVTLPKLQLIAITSLLIAAKFEEVNLPKLSNYSYITDNAYSNDE 245
TLYL+IN++DR+LS VTL + QL+ +++L IAAKFEE+N P L + Y+ +N Y+ D+
Sbjct: 260 TLYLTINIVDRFLSKKTVTLNRFQLVGVSALFIAAKFEEINCPTLDDLVYMLENTYTRDD 319
Query: 246 IKQAEFVILNKLEYNIGWPNPLNFLRRISRCDEYDSITRTLGKCLIGYMISCPHFIDVVP 305
I +AE +++ LE+ IGWP P+ FLRRIS+ D+YD RTL K L+ I P + P
Sbjct: 320 IIRAEQYMIDTLEFEIGWPGPMPFLRRISKADDYDFEPRTLAKYLLETTIVEPKLVAAAP 379
Query: 306 SKIASVAMFTAQRIVHEDFQWDELWDYYSCFSFKDNEIELKELSQILINDIAKPTTQLNA 365
S +A+ A F ++ I+ + W +YS ++ ++ L+ +++ + + + ++
Sbjct: 380 SWLAAGAYFLSRTILGSN-DWSLKHVFYSGYT----SSQIIPLASLILENCKNASRRHHS 434
Query: 366 LIHKY 370
+ KY
Sbjct: 435 IWKKY 439
>Hs4757930 [D] KOG0653 Cyclin B and related kinase-activating proteins
Length = 398
Score = 166 bits (421), Expect = 4e-41
Identities = 93/253 (36%), Positives = 154/253 (60%), Gaps = 13/253 (5%)
Query: 117 DSQDKEDVTMCYDYSDDIFDHLYTRQFETTPKIN--YLKDKNYEFYLRPTMRSILVDWII 174
D++D E+ +C DY DI+ +L RQ E IN +L ++ + MR+ILVDW++
Sbjct: 121 DNEDWENPQLCSDYVKDIYQYL--RQLEVLQSINPHFLDGRD----INGRMRAILVDWLV 174
Query: 175 EVHCKFQLLPETLYLSINLMDRYLSFNKVTLPKLQLIAITSLLIAAKFEEVNLPKLSNYS 234
+VH KF+LL ETLY+ + +MDR+L V+ KLQL+ IT+LL+A+K+EE+ P + ++
Sbjct: 175 QVHSKFRLLQETLYMCVGIMDRFLQVQPVSRKKLQLVGITALLLASKYEEMFSPNIEDFV 234
Query: 235 YITDNAYSNDEIKQAEFVILNKLEYNIGWPNPLNFLRRISRCDEYDSITRTLGKCLIGYM 294
YITDNAY++ +I++ E +IL +L++ +G P PL+FLRR S+ E D TL K L+
Sbjct: 235 YITDNAYTSSQIREMETLILKELKFELGRPLPLHFLRRASKAGEVDVEQHTLAKYLMELT 294
Query: 295 ISCPHFIDVVPSKIASVAMFTAQRIVHEDFQWDELWDYYSCFSFKDNEIELKELSQILIN 354
+ + PSK+A+ A +Q+++ + +W+ YY+ ++ E E+ E+ Q +
Sbjct: 295 LIDYDMVHYHPSKVAAAASCLSQKVLGQG-KWNLKQQYYTGYT----ENEVLEVMQHMAK 349
Query: 355 DIAKPTTQLNALI 367
++ K L I
Sbjct: 350 NVVKVNENLTKFI 362
>SPAPB2B4.03 [D] KOG0653 Cyclin B and related kinase-activating proteins
Length = 411
Score = 159 bits (401), Expect = 9e-39
Identities = 90/245 (36%), Positives = 149/245 (60%), Gaps = 8/245 (3%)
Query: 126 MCYDYSDDIFDHLYTRQFETTPKINYLKDKNYEFYLRPTMRSILVDWIIEVHCKFQLLPE 185
M +Y+ +IF+++ + P Y+ D+ E + MR IL +W++E+H F L+PE
Sbjct: 132 MAEEYAPEIFEYIRKLDLKCLPNPKYM-DQQKELTWK--MREILNEWLVEIHSNFCLMPE 188
Query: 186 TLYLSINLMDRYLSFNKVTLPKLQLIAITSLLIAAKFEEVNLPKLSNYSYITDNAYSNDE 245
TLYL++N++DR+LS +L K QL IT+LLIA+K+EEV P + N+ Y+TD A++ ++
Sbjct: 189 TLYLAVNIIDRFLSRRSCSLSKFQLTGITALLIASKYEEVMCPSIQNFVYMTDGAFTVED 248
Query: 246 IKQAEFVILNKLEYNIGWPNPLNFLRRISRCDEYDSITRTLGKCLIGYMISCPHFIDVVP 305
+ AE +LN L +++ +P+PLNFLR+IS+ + YD+ TRTLGK L + +
Sbjct: 249 VCVAERYMLNVLNFDLSYPSPLNFLRKISQAEGYDAQTRTLGKYLTEIYLFDHDLLRYPM 308
Query: 306 SKIASVAMFTAQRIVHEDFQWDELWDYYSCFSFKDNEIELKELSQILINDIAKPTTQLNA 365
SKIA+ AM+ ++R++ +L + + E ELKE++ I+++ KP + A
Sbjct: 309 SKIAAAAMYLSRRLLRRGPWTPKLVESSGGY----EEHELKEIAYIMLHYHNKP-LEHKA 363
Query: 366 LIHKY 370
KY
Sbjct: 364 FFQKY 368
>At1g77390 [D] KOG0654 G2/Mitotic-specific cyclin A
Length = 454
Score = 145 bits (366), Expect = 1e-34
Identities = 79/238 (33%), Positives = 137/238 (57%), Gaps = 8/238 (3%)
Query: 120 DKEDVTMCYDYSDDIFDHLYTRQFETTPKINYLKDKNYEFYLRPTMRSILVDWIIEVHCK 179
D D +C ++ DI++HL + P ++Y++ + + +MRSIL+DW++EV +
Sbjct: 168 DLMDPQLCASFACDIYEHLRVSEVNKRPALDYME--RTQSSINASMRSILIDWLVEVAEE 225
Query: 180 FQLLPETLYLSINLMDRYLSFNKVTLPKLQLIAITSLLIAAKFEEVNLPKLSNYSYITDN 239
++L PETLYL++N +DRYL+ N + LQL+ +T ++IAAK+EEV +P++ ++ YITDN
Sbjct: 226 YRLSPETLYLAVNYVDRYLTGNAINKQNLQLLGVTCMMIAAKYEEVCVPQVEDFCYITDN 285
Query: 240 AYSNDEIKQAEFVILNKLEYNIGWPNPLNFLRRISRCDE-YDSITRTLGKCLIGYMISCP 298
Y +E+ + E +LN L++ + P FLRR R + + L +CL Y+
Sbjct: 286 TYLRNELLEMESSVLNYLKFELTTPTAKCFLRRFLRAAQGRKEVPSLLSECLACYLTELS 345
Query: 299 ----HFIDVVPSKIASVAMFTAQRIVHEDFQ-WDELWDYYSCFSFKDNEIELKELSQI 351
+ PS +A+ A+F AQ +H + W+ ++Y+ + K E +K L Q+
Sbjct: 346 LLDYAMLRYAPSLVAASAVFLAQYTLHPSRKPWNATLEHYTSYRAKHMEACVKNLLQL 403
>Hs14327896 [D] KOG0653 Cyclin B and related kinase-activating proteins
Length = 433
Score = 142 bits (358), Expect = 9e-34
Identities = 73/221 (33%), Positives = 132/221 (59%), Gaps = 5/221 (2%)
Query: 117 DSQDKEDVTMCYDYSDDIFDHLYTRQFETTPKINYLKDKNYEFYLRPTMRSILVDWIIEV 176
D++D D +C +Y DI+ +L + E + YL + + MR+IL+DW+++V
Sbjct: 157 DAEDGADPNLCSEYVKDIYAYLRQLEEEQAVRPKYLLGRE----VTGNMRAILIDWLVQV 212
Query: 177 HCKFQLLPETLYLSINLMDRYLSFNKVTLPKLQLIAITSLLIAAKFEEVNLPKLSNYSYI 236
KF+LL ET+Y++++++DR++ N V LQL+ +T++ IA+K+EE+ P++ +++++
Sbjct: 213 QMKFRLLQETMYMTVSIIDRFMQNNCVPKKMLQLVGVTAMFIASKYEEMYPPEIGDFAFV 272
Query: 237 TDNAYSNDEIKQAEFVILNKLEYNIGWPNPLNFLRRISRCDEYDSITRTLGKCLIGYMIS 296
TDN Y+ +I+Q E IL L + +G P PL+FLRR S+ E D TL K L+ +
Sbjct: 273 TDNTYTKHQIRQMEMKILRALNFGLGRPLPLHFLRRASKIGEVDVEQHTLAKYLMELTML 332
Query: 297 CPHFIDVVPSKIASVAMFTAQRIVHEDFQWDELWDYYSCFS 337
+ PS+IA+ A A +I+ ++ +W +Y ++
Sbjct: 333 DYDMVHFPPSQIAAGAFCLALKIL-DNGEWTPTLQHYLSYT 372
>At1g20610 [D] KOG0653 Cyclin B and related kinase-activating proteins
Length = 429
Score = 138 bits (348), Expect = 1e-32
Identities = 74/225 (32%), Positives = 133/225 (58%), Gaps = 7/225 (3%)
Query: 117 DSQDKEDVTMCYDYSDDIFDHLYTRQFETTPKI--NYLKDKNYEFYLRPTMRSILVDWII 174
D+ DK + +Y D+ H + + FE + NY+ ++ L MR IL+DW+I
Sbjct: 164 DACDKNNPLAAVEYIHDM--HTFYKNFEKLSCVPPNYMDNQQD---LNERMRGILIDWLI 218
Query: 175 EVHCKFQLLPETLYLSINLMDRYLSFNKVTLPKLQLIAITSLLIAAKFEEVNLPKLSNYS 234
EVH KF+L+ ETLYL+IN++DR+L+ +++ KLQL+ +T+LL+A K+EEV++P + +
Sbjct: 219 EVHYKFELMEETLYLTINVIDRFLAVHQIVRKKLQLVGVTALLLACKYEEVSVPVVDDLI 278
Query: 235 YITDNAYSNDEIKQAEFVILNKLEYNIGWPNPLNFLRRISRCDEYDSITRTLGKCLIGYM 294
I+D AYS E+ E ++ N L++N P P F++R + + D L +I
Sbjct: 279 LISDKAYSRREVLDMEKLMANTLQFNFSLPTPYVFMKRFLKAAQSDKKLEILSFFMIELC 338
Query: 295 ISCPHFIDVVPSKIASVAMFTAQRIVHEDFQWDELWDYYSCFSFK 339
+ ++ +PSK+A+ A++TAQ + +W + ++++ ++ K
Sbjct: 339 LVEYEMLEYLPSKLAASAIYTAQCTLKGFEEWSKTCEFHTGYNEK 383
>ECU08g0260 [D] KOG0653 Cyclin B and related kinase-activating proteins
Length = 300
Score = 137 bits (346), Expect = 2e-32
Identities = 84/240 (35%), Positives = 140/240 (58%), Gaps = 16/240 (6%)
Query: 120 DKEDVTMCYDYSDDIFDHLYTRQFETTPK-INYLKDKNYEFYLRPTMRSILVDWIIEVHC 178
+ + M YSDD+F++ F T K Y+ D + MRS+LVDWII++H
Sbjct: 44 EASQIVMVDKYSDDVFEY-----FSTIDKPFVYINDG-----VSWKMRSLLVDWIIDIHD 93
Query: 179 KFQLLPETLYLSINLMDRYLSFNKVTLPKLQLIAITSLLIAAKFEEVNLPKLSNYSYITD 238
K L +TL+L+IN +DR+LS + KLQL+ I++L+IA K+EEV P L +T+
Sbjct: 94 KLGLCHDTLFLAINFIDRFLSMRSIPSSKLQLVGISALMIACKYEEVVCPALQTLVLLTE 153
Query: 239 NAYSNDEIKQAEFVILNKLEYNIGWPNPLNFLRRISRCDEYDSITRTLGKCLIGYMISCP 298
+ +++++AE +L+ L Y++ + +PLNFLR+ S+ + Y+ +RT+GK L+ M
Sbjct: 154 KTLTGEDVRKAEKYMLHTLNYDLQYVSPLNFLRKCSKANNYEICSRTVGKYLLELMTLYE 213
Query: 299 HFIDVVPSKIASVAMFTAQRIVHEDFQWDELWDYYSCFSFKDNEIELKELSQILINDIAK 358
F+ S A+ AM+ A++I +D Q L+ YS + KD ++KE L++ I++
Sbjct: 214 EFLRFKGSVRAAAAMYLARKITSQD-QCKNLFIMYSGHT-KD---DIKECFNALVHTISE 268
>SPCC4E9.02 [D] KOG0653 Cyclin B and related kinase-activating proteins
Length = 310
Score = 137 bits (345), Expect = 3e-32
Identities = 65/158 (41%), Positives = 108/158 (68%), Gaps = 3/158 (1%)
Query: 123 DVTMCYDYSDDIFDHLYTRQFETTPKINYLKDKNYEFYLRPTMRSILVDWIIEVHCKFQL 182
D +M DY +IF ++ + + + P NY+ + ++ R +LVDWI++V F+L
Sbjct: 156 DPSMVPDYDPEIFHYMQSLERKLAPPPNYMSVQQEIDWVT---RHMLVDWIVQVQIHFRL 212
Query: 183 LPETLYLSINLMDRYLSFNKVTLPKLQLIAITSLLIAAKFEEVNLPKLSNYSYITDNAYS 242
LPETL+L++NL+DR+LS V+L K+QL+ +++LLIA K+EE++ P + N++++ ++
Sbjct: 213 LPETLFLAVNLIDRFLSIKVVSLQKVQLVGLSALLIACKYEEIHPPSIYNFAHVVQGIFT 272
Query: 243 NDEIKQAEFVILNKLEYNIGWPNPLNFLRRISRCDEYD 280
DEI +AE +L L+++I WP P++FLRRISR D YD
Sbjct: 273 VDEIIRAERYMLMLLDFDISWPGPMSFLRRISRADSYD 310
>At4g35620 [D] KOG0653 Cyclin B and related kinase-activating proteins
Length = 429
Score = 137 bits (344), Expect = 4e-32
Identities = 72/222 (32%), Positives = 129/222 (57%), Gaps = 5/222 (2%)
Query: 117 DSQDKEDVTMCYDYSDDIFD-HLYTRQFETTPKINYLKDKNYEFYLRPTMRSILVDWIIE 175
D D + +Y D++D + T +F P ++Y+ +F + MR+IL+DW+IE
Sbjct: 159 DEYDANNSLAAVEYVQDLYDFYRKTERFSCVP-LDYMAQ---QFDISDKMRAILIDWLIE 214
Query: 176 VHCKFQLLPETLYLSINLMDRYLSFNKVTLPKLQLIAITSLLIAAKFEEVNLPKLSNYSY 235
VH KF+L+ ETL+L++NL+DR+LS V KLQL+ + +LL+A K+EEV++P + +
Sbjct: 215 VHDKFELMNETLFLTVNLIDRFLSKQAVARKKLQLVGLVALLLACKYEEVSVPIVEDLVV 274
Query: 236 ITDNAYSNDEIKQAEFVILNKLEYNIGWPNPLNFLRRISRCDEYDSITRTLGKCLIGYMI 295
I+D AY+ ++ + E ++L+ L++N+ P FL+R + + D L LI +
Sbjct: 275 ISDKAYTRTDVLEMEKIMLSTLQFNMSLPTQYPFLKRFLKAAQSDKKLEILASFLIELAL 334
Query: 296 SCPHFIDVVPSKIASVAMFTAQRIVHEDFQWDELWDYYSCFS 337
+ PS +A+ A++TAQ +H +W+ +++ +S
Sbjct: 335 VDYEMVRYPPSLLAATAVYTAQCTIHGFSEWNSTCEFHCHYS 376
>At5g25380 [D] KOG0654 G2/Mitotic-specific cyclin A
Length = 444
Score = 134 bits (338), Expect = 2e-31
Identities = 75/236 (31%), Positives = 132/236 (55%), Gaps = 11/236 (4%)
Query: 122 EDVTMCYDYSDDIFDHLYTRQFETTPKINYLKDKNYEFYLRPTMRSILVDWIIEVHCKFQ 181
+D C Y+ I+D + + E P +Y+ + + PTMR IL+DW++EV +++
Sbjct: 172 QDPQFCSLYAASIYDSINVAELEQRPSTSYMVQVQRD--IDPTMRGILIDWLVEVSEEYK 229
Query: 182 LLPETLYLSINLMDRYLSFNKVTLPKLQLIAITSLLIAAKFEEVNLPKLSNYSYITDNAY 241
L+ +TLYL++NL+DR++S N + KLQL+ IT +LIA+K+EE++ P+L + +ITDN Y
Sbjct: 230 LVSDTLYLTVNLIDRFMSHNYIEKQKLQLLGITCMLIASKYEEISAPRLEEFCFITDNTY 289
Query: 242 SNDEIKQAEFVILNKLEYNIGWPNPLNFLRRISRCDE-YDSITRTLGKCLIGYMISCP-- 298
+ E+ E +LN L + + P FLRR R + D + + L Y
Sbjct: 290 TRLEVLSMEIKVLNSLHFRLSVPTTKTFLRRFIRAAQASDKVPLIEMEYLANYFAELTLT 349
Query: 299 --HFIDVVPSKIASVAMFTAQ-RIVHEDFQWDELWDYYSCF---SFKDNEIELKEL 348
F+ +PS IA+ A+F A+ + + W++ +Y+ + + K+ + ++EL
Sbjct: 350 EYTFLRFLPSLIAASAVFLARWTLDQSNHPWNQTLQHYTRYETSALKNTVLAMEEL 405
>At5g43080 [D] KOG0654 G2/Mitotic-specific cyclin A
Length = 355
Score = 132 bits (333), Expect = 7e-31
Identities = 82/259 (31%), Positives = 147/259 (56%), Gaps = 15/259 (5%)
Query: 122 EDVTMCYDYSDDIFDHLYTRQFETTPKINYLKDKNYEFYLRPTMRSILVDWIIEVHCKFQ 181
+D MC Y IF++L + ++ P ++Y++ + + MR +LVDW++EV +++
Sbjct: 79 DDPQMCGPYVTSIFEYLRQLEVKSRPLVDYIEKIQKD--VTSNMRGVLVDWLVEVAEEYK 136
Query: 182 LLPETLYLSINLMDRYLSFNKVTLPKLQLIAITSLLIAAKFEEVNLPKLSNYSYITDNAY 241
LL +TLYL+++ +DR+LS V +LQL+ +TS+LIA+K+EE+ P + ++ YITDN Y
Sbjct: 137 LLSDTLYLAVSYIDRFLSLKTVNKQRLQLLGVTSMLIASKYEEITPPNVDDFCYITDNTY 196
Query: 242 SNDEIKQAEFVILNKLEYNIGWPNPLNFLRRISRCDEYD-SITRTLGKCLIGYMISCP-- 298
+ EI + E IL L++ +G P FLRR +R + D ++ + L Y+
Sbjct: 197 TKQEIVKMEADILLALQFELGNPTSNTFLRRFTRVAQEDFEMSHLQMEFLCSYLSELSML 256
Query: 299 --HFIDVVPSKIASVAMFTAQRIVH-EDFQWDELWDYYSCFSFKDNEIELKELSQILIND 355
+ +PS +A+ A+F A+ I+ + W+ + + Y+ + D LKE +I+D
Sbjct: 257 DYQSVKFLPSTVAASAVFLARFIIRPKQHPWNVMLEEYTRYKAGD----LKE-CVAMIHD 311
Query: 356 --IAKPTTQLNALIHKYKK 372
+++ L A+ KYK+
Sbjct: 312 LYLSRKCGALEAIREKYKQ 330
>At1g80370 [D] KOG0654 G2/Mitotic-specific cyclin A
Length = 461
Score = 132 bits (332), Expect = 9e-31
Identities = 94/355 (26%), Positives = 173/355 (48%), Gaps = 18/355 (5%)
Query: 25 KRVALSEQPLHDNKLKSSVGSLRNSQVDEGKNKIYGNSSQTTSSVSLKRQIYRDDDDEEQ 84
K++ Q +K+ SS + SQV + K ++ NS+ + SV + +E
Sbjct: 97 KQIKKGRQSSSSSKVASSSAT---SQVTDAKVEVVSNSAGASLSVFTDTSL---GTNETS 150
Query: 85 KSDVRSDDDILEPRKSHKXXXXXXXXXXXXXXD-SQDKEDVTMCYDYSDDIFDHLYTRQF 143
S + PR D D +D +C Y+ DI+ +L +
Sbjct: 151 YSIIAKPSSRSPPRPFGTVERSCGGASSPKFVDIDSDDKDPLLCSLYAPDIYYNLRVAEL 210
Query: 144 ETTPKINYLKDKNYEFYLRPTMRSILVDWIIEVHCKFQLLPETLYLSINLMDRYLSFNKV 203
+ P ++++ + + TMR ILVDW++EV ++ L+P+TLYL++ L+D +L N V
Sbjct: 211 KRRPFPDFMEKTQRD--VTETMRGILVDWLVEVSEEYTLVPDTLYLTVYLIDWFLHGNYV 268
Query: 204 TLPKLQLIAITSLLIAAKFEEVNLPKLSNYSYITDNAYSNDEIKQAEFVILNKLEYNIGW 263
+LQL+ IT +LIA+K+EE++ P++ + +ITDN Y+ D++ + E +L + I
Sbjct: 269 ERQRLQLLGITCMLIASKYEEIHAPRIEEFCFITDNTYTRDQVLEMESQVLKHFSFQIYT 328
Query: 264 PNPLNFLRRISRCDEYDSITRTLG-KCLIGYMISCP----HFIDVVPSKIASVAMFTAQR 318
P FLRR R + ++L + L Y+ F+ +PS IA+ A+F A+
Sbjct: 329 PTSKTFLRRFLRAAQVSFPNQSLEMEFLANYLTELTLMDYPFLKFLPSIIAASAVFLAKW 388
Query: 319 IVHE-DFQWDELWDYYSCFSFKDNEIELKELSQILINDIAKPTTQLNALIHKYKK 372
+++ W+ ++Y+ + D + + L + +N LN++ KY++
Sbjct: 389 TLNQSSHPWNPTLEHYTTYKASDLKASVHALQDLQLN---TKGCSLNSIRMKYRQ 440
>At2g17620 [D] KOG0653 Cyclin B and related kinase-activating proteins
Length = 429
Score = 131 bits (329), Expect = 2e-30
Identities = 77/255 (30%), Positives = 139/255 (54%), Gaps = 8/255 (3%)
Query: 117 DSQDKEDVTMCYDYSDDIFDHLYTRQFETTPKINYLKDKNYEFYLRPTMRSILVDWIIEV 176
D D ++ +Y D++ T + + ++Y+ + L MR+IL+DW+IEV
Sbjct: 158 DVLDSKNSLAAVEYVQDLYAFYRTMERFSCVPVDYMMQ---QIDLNEKMRAILIDWLIEV 214
Query: 177 HCKFQLLPETLYLSINLMDRYLSFNKVTLPKLQLIAITSLLIAAKFEEVNLPKLSNYSYI 236
H KF L+ ETL+L++NL+DR+LS V KLQL+ + +LL+A K+EEV++P + + I
Sbjct: 215 HDKFDLINETLFLTVNLIDRFLSKQNVMRKKLQLVGLVALLLACKYEEVSVPVVEDLVLI 274
Query: 237 TDNAYSNDEIKQAEFVILNKLEYNIGWPNPLNFLRRISRCDEYDSITRTLGKCLIGYMIS 296
+D AY+ +++ + E +L+ L++NI P FL+R + + D L LI +
Sbjct: 275 SDKAYTRNDVLEMEKTMLSTLQFNISLPTQYPFLKRFLKAAQADKKCEVLASFLIELALV 334
Query: 297 CPHFIDVVPSKIASVAMFTAQRIVHEDFQWDELWDYYSCFSFKDNEIELKELSQILINDI 356
+ PS +A+ +++TAQ + +W+ +++ +S E +L E S+ L++
Sbjct: 335 EYEMLRFPPSLLAATSVYTAQCTLDGSRKWNSTCEFHCHYS----EDQLMECSRKLVSLH 390
Query: 357 AKPTT-QLNALIHKY 370
+ T L + KY
Sbjct: 391 QRAATGNLTGVYRKY 405
>At1g47210 [D] KOG0654 G2/Mitotic-specific cyclin A
Length = 372
Score = 130 bits (328), Expect = 3e-30
Identities = 90/325 (27%), Positives = 168/325 (51%), Gaps = 18/325 (5%)
Query: 55 KNKIYGNSSQTTSSVSLKRQIYRDDDDEEQKSDVRSDDDILEPRKSHKXXXXXXXXXXXX 114
K ++ S+V+L + + + ++ K +++ P K K
Sbjct: 32 KKRVVLGELLNVSNVNLLANLNQKKETQKPKRNLKPP-----PAKQIKSAPVAIIDLESK 86
Query: 115 XXDSQDKEDVTMCYDYSDDIFDHLYTRQFETTPKINYLKD--KNYEFYLRPTMRSILVDW 172
+D MC Y DI+++L RQ E PK L D + + + P+MR +LVDW
Sbjct: 87 SDIDSRSDDPQMCGPYVADIYEYL--RQLEVKPKQRPLPDYIEKVQKDVTPSMRGVLVDW 144
Query: 173 IIEVHCKFQLLPETLYLSINLMDRYLSFNKVTLPKLQLIAITSLLIAAKFEEVNLPKLSN 232
++EV +++L ETLYL+++ +DR+LS V KLQL+ ++++LIA+K+EE++ PK+ +
Sbjct: 145 LVEVAEEYKLGSETLYLTVSHIDRFLSLKTVNKQKLQLVGVSAMLIASKYEEISPPKVDD 204
Query: 233 YSYITDNAYSNDEIKQAEFVILNKLEYNIGWPNPLNFLRRISRCDEYD-SITRTLGKCLI 291
+ YITDN +S ++ + E IL L++ +G P F+RR +R + D + + L
Sbjct: 205 FCYITDNTFSKQDVVKMEADILLALQFELGRPTINTFMRRFTRVAQDDFKVPHLQLEPLC 264
Query: 292 GYM----ISCPHFIDVVPSKIASVAMFTAQRIVH-EDFQWDELWDYYSCFSFKDNEIELK 346
Y+ I + VPS +A+ A+F A+ I+ + W+++ + Y+ + D ++ +
Sbjct: 265 CYLSELSILDYKTVKFVPSLLAASAVFLARFIIRPKQHPWNQMLEEYTKYKAADLQVCVG 324
Query: 347 ELSQILINDIAKPTTQLNALIHKYK 371
+ + +++ L A+ KYK
Sbjct: 325 IIHDLY---LSRRGGALQAVREKYK 346
>At1g44110 [D] KOG0654 G2/Mitotic-specific cyclin A
Length = 460
Score = 130 bits (328), Expect = 3e-30
Identities = 80/258 (31%), Positives = 141/258 (54%), Gaps = 12/258 (4%)
Query: 123 DVTMCYDYSDDIFDHLYTRQFETTPKINYLKDKNYEFYLRPTMRSILVDWIIEVHCKFQL 182
D +C ++ DI+ HL + + P ++Y++ + + +MR ILVDW+IEV +++L
Sbjct: 187 DPQLCATFACDIYKHLRASEAKKRPDVDYMERVQKD--VNSSMRGILVDWLIEVSEEYRL 244
Query: 183 LPETLYLSINLMDRYLSFNKVTLPKLQLIAITSLLIAAKFEEVNLPKLSNYSYITDNAYS 242
+PETLYL++N +DRYLS N ++ KLQL+ + ++IAAK+EE+ P++ + YITDN Y
Sbjct: 245 VPETLYLTVNYIDRYLSGNVISRQKLQLLGVACMMIAAKYEEICAPQVEEFCYITDNTYL 304
Query: 243 NDEIKQAEFVILNKLEYNIGWPNPLNFLRRISRCDE--YDSITRTLGKCLIGYMISCP-- 298
DE+ E +LN L++ + P FLRR R +++ L +C+ Y+
Sbjct: 305 KDEVLDMESDVLNYLKFEMTAPTTKCFLRRFVRAAHGVHEAPLMQL-ECMANYIAELSLL 363
Query: 299 --HFIDVVPSKIASVAMFTAQRIVHEDFQ-WDELWDYYSCFSFKDNEIELKELSQI--LI 353
+ PS +A+ A+F A+ I+ + W+ +Y+ + + +K+L ++
Sbjct: 364 EYTMLSHSPSLVAASAIFLAKYILDPTRRPWNSTLQHYTQYKAMELRGCVKDLQRLCSTA 423
Query: 354 NDIAKPTTQLNALIHKYK 371
+ P + HKYK
Sbjct: 424 HGSTLPAVREKYSQHKYK 441
>At1g15570 [D] KOG0654 G2/Mitotic-specific cyclin A
Length = 450
Score = 129 bits (323), Expect = 1e-29
Identities = 77/262 (29%), Positives = 145/262 (54%), Gaps = 12/262 (4%)
Query: 117 DSQDKEDVTMCYDYSDDIFDHLYTRQFETTPKINYLKDKNYEFYLRPTMRSILVDWIIEV 176
DS DK+ + C Y+ +I +L + + P ++++ + + +MR ILVDW++EV
Sbjct: 176 DSDDKDPLLCCL-YAPEIHYNLRVSELKRRPLPDFMERIQKD--VTQSMRGILVDWLVEV 232
Query: 177 HCKFQLLPETLYLSINLMDRYLSFNKVTLPKLQLIAITSLLIAAKFEEVNLPKLSNYSYI 236
++ L +TLYL++ L+D +L N V +LQL+ IT +LIA+K+EE++ P++ + +I
Sbjct: 233 SEEYTLASDTLYLTVYLIDWFLHGNYVQRQQLQLLGITCMLIASKYEEISAPRIEEFCFI 292
Query: 237 TDNAYSNDEIKQAEFVILNKLEYNIGWPNPLNFLRRISRCDEYDSITRTLG-KCLIGYMI 295
TDN Y+ D++ + E +L + I P P FLRR R + ++ +L + L Y+
Sbjct: 293 TDNTYTRDQVLEMENQVLKHFSFQIYTPTPKTFLRRFLRAAQASRLSPSLEVEFLASYLT 352
Query: 296 SCP----HFIDVVPSKIASVAMFTAQRIVHE-DFQWDELWDYYSCFSFKDNEIELKELSQ 350
HF+ +PS +A+ A+F A+ + + + W+ ++Y+ + D + + L
Sbjct: 353 ELTLIDYHFLKFLPSVVAASAVFLAKWTMDQSNHPWNPTLEHYTTYKASDLKASVHALQD 412
Query: 351 ILINDIAKPTTQLNALIHKYKK 372
+ +N P L+A+ KY++
Sbjct: 413 LQLNTKGCP---LSAIRMKYRQ 431
>At5g06150 [D] KOG0653 Cyclin B and related kinase-activating proteins
Length = 445
Score = 128 bits (322), Expect = 1e-29
Identities = 95/354 (26%), Positives = 178/354 (49%), Gaps = 20/354 (5%)
Query: 29 LSEQPLH-DNKL-----KSSVGSLRNSQVDEG---KNKIYGNSSQTTSSVSLKRQIYRDD 79
L +P++ DNK+ K + RN + KN + ++ + K+++ + +
Sbjct: 74 LERKPINGDNKVPALGPKRQPLAARNPEAQRAVQKKNLVVKQQTKPVEVIETKKEVTKKE 133
Query: 80 DDEEQKSDVRSDDDILEPRKSHKXXXXXXXXXXXXXXDSQDKEDVTMCYDYSDDIFDHLY 139
K+ + +L R K D DK++ +Y DD++
Sbjct: 134 VAMSPKNKKVTYSSVLSARS--KAACGIVNKPKIIDIDESDKDNHLAAVEYVDDMYSFYK 191
Query: 140 TRQFETTPKINYLKDKNYEFYLRPTMRSILVDWIIEVHCKFQLLPETLYLSINLMDRYLS 199
+ E+ PK+ Y+ + + + MR+IL+DW++EVH KF+L ETLYL++N++DR+LS
Sbjct: 192 EVEKESQPKM-YM---HIQTEMNEKMRAILIDWLLEVHIKFELNLETLYLTVNIIDRFLS 247
Query: 200 FNKVTLPKLQLIAITSLLIAAKFEEVNLPKLSNYSYITDNAYSNDEIKQAEFVILNKLEY 259
V +LQL+ I++LLIA+K+EE+ P++++ Y+TDNAYS+ +I E IL LE+
Sbjct: 248 VKAVPKRELQLVGISALLIASKYEEIWPPQVNDLVYVTDNAYSSRQILVMEKAILGNLEW 307
Query: 260 NIGWPNPLNFLRRISRCDEYDSITRTLGKCLIGYMISCPHFIDVVPSKIASVAMFTAQRI 319
+ P FL R + D + L + + PS +A+ A++TA+
Sbjct: 308 YLTVPTQYVFLVRFIKASMSDPEMENMVHFLAELGMMHYDTLTFCPSMLAASAVYTARCS 367
Query: 320 VHEDFQWDELWDYYSCFSFKDNEIELKELSQILINDIAK-PTTQLNALIHKYKK 372
+++ W + +++ ++ E E+ + S++L ++ ++L A+ KY K
Sbjct: 368 LNKSPAWTDTLQFHTGYT----ESEIMDCSKLLAFLHSRCGESRLRAVYKKYSK 417
>At3g11520 [D] KOG0653 Cyclin B and related kinase-activating proteins
Length = 427
Score = 128 bits (321), Expect = 2e-29
Identities = 80/259 (30%), Positives = 142/259 (53%), Gaps = 9/259 (3%)
Query: 117 DSQDKEDVTMCYDYSDDIFDHLYTRQFETTPKINYLKDKNYEFYLRPTMRSILVDWIIEV 176
D DKE+ +Y +D++ E+ P++ + MRSIL+DW++EV
Sbjct: 159 DYVDKENDLAAVEYVEDMYIFYKEVVNESKPQMYMHTQPEID----EKMRSILIDWLVEV 214
Query: 177 HCKFQLLPETLYLSINLMDRYLSFNKVTLPKLQLIAITSLLIAAKFEEVNLPKLSNYSYI 236
H KF L PETLYL++N++DR+LS V +LQL+ +++LLIA+K+EE+ P++++ Y+
Sbjct: 215 HVKFDLSPETLYLTVNIIDRFLSLKTVPRRELQLVGVSALLIASKYEEIWPPQVNDLVYV 274
Query: 237 TDNAYSNDEIKQAEFVILNKLEYNIGWPNPLNFLRRISRCDEYDSITRTLGKCLIGYMIS 296
TDN+Y++ +I E IL LE+ + P FL R + D L L +
Sbjct: 275 TDNSYNSRQILVMEKTILGNLEWYLTVPTQYVFLVRFIKASGSDQKLENLVHFLAELGLM 334
Query: 297 CPHFIDVVPSKIASVAMFTAQRIVHEDFQWDELWDYYSCFSFKDNEIELKELSQILINDI 356
+ PS +A+ A++TA+ +++ W + +++ +S E +L + S++L
Sbjct: 335 HHDSLMFCPSMLAASAVYTARCCLNKTPTWTDTLKFHTGYS----ESQLMDCSKLLAFIH 390
Query: 357 AKP-TTQLNALIHKYKKIG 374
+K ++L ++ KY K+G
Sbjct: 391 SKAGESKLRGVLKKYSKLG 409
>At1g47230 [D] KOG0654 G2/Mitotic-specific cyclin A
Length = 369
Score = 128 bits (321), Expect = 2e-29
Identities = 80/258 (31%), Positives = 146/258 (56%), Gaps = 13/258 (5%)
Query: 123 DVTMCYDYSDDIFDHLYTRQFETTPKINYLKD--KNYEFYLRPTMRSILVDWIIEVHCKF 180
D MC ++ DI Y R+ E PK L D + + L P MR++LVDW++EV ++
Sbjct: 88 DPQMCEPFASDIC--AYLREMEGKPKHRPLPDYIEKVQSDLTPHMRAVLVDWLVEVAEEY 145
Query: 181 QLLPETLYLSINLMDRYLSFNKVTLPKLQLIAITSLLIAAKFEEVNLPKLSNYSYITDNA 240
+L+ +TLYL+I+ +DR+LS + KLQL+ ++++LIA+K+EE+ PK+ ++ YITDN
Sbjct: 146 KLVSDTLYLTISYVDRFLSVKPINRQKLQLVGVSAMLIASKYEEIGPPKVEDFCYITDNT 205
Query: 241 YSNDEIKQAEFVILNKLEYNIGWPNPLNFLRRISRC---DEYDSITRTLGKCLIGYMISC 297
++ E+ E IL L++ +G P FLRR +R D DS + C +S
Sbjct: 206 FTKQEVVSMEADILLALQFELGSPTIKTFLRRFTRVAQEDFKDSQLQIEFLCCYLSELSM 265
Query: 298 PHF--IDVVPSKIASVAMFTAQRIVH-EDFQWDELWDYYSCFSFKDNEIELKELSQILIN 354
+ + +PS +++ A+F A+ I+ + W+++ + Y+ + D ++ + + +
Sbjct: 266 LDYTCVKYLPSLLSASAVFLARFIIRPKQHPWNQMLEEYTKYKAADLQVCVGIIHDLY-- 323
Query: 355 DIAKPTTQLNALIHKYKK 372
+++ L A+ +KYK+
Sbjct: 324 -LSRRGNTLEAVRNKYKQ 340
>7291478 [D] KOG0653 Cyclin B and related kinase-activating proteins
Length = 530
Score = 125 bits (315), Expect = 9e-29
Identities = 81/267 (30%), Positives = 143/267 (53%), Gaps = 20/267 (7%)
Query: 117 DSQDKEDVTMCYDYSDDIFDHLYTRQFETTPKINYLKDKNYEFYLRPTMRSILVDWIIEV 176
D+ DKE++ + +Y +DI+D+LY + E ++L + + MR++L+DWI EV
Sbjct: 244 DANDKENLVLVSEYVNDIYDYLYQVELEQPIHKDHLAGQKEVSH---KMRAVLIDWINEV 300
Query: 177 HCKFQLLPETLYLSINLMDRYLSFNKVTLPK-LQLIAITSLLIAAKFEEVNLPKLSNYSY 235
H +F L ET L++ ++DRYL K T LQL+ +T+L IA K+EE+ P + ++ +
Sbjct: 301 HLQFHLAAETFQLAVAIIDRYLQVVKDTKRTYLQLVGVTALFIATKYEELFPPAIGDFVF 360
Query: 236 ITDNAYSNDEIKQAEFVILNKLEYNIGWPNPLNFLRRISRCDEYDSITRTLGKCLIGYMI 295
ITD+ Y+ +I+Q E I ++ N+ P P++FLRR S+ + T+ K I
Sbjct: 361 ITDDTYTARQIRQMELQIFKAIDCNLSRPLPIHFLRRYSKAAGAEDEHHTMSKYFIELAS 420
Query: 296 SCPHFIDVVPSKIASVAMFTAQRIVH---------EDFQWDELWDYYSCFSFKDNEIELK 346
PS+IA+ ++F + +++ D W +YS +S L+
Sbjct: 421 VDYEMATYRPSEIAAASLFLSLHLLNGNHRAGTGFNDRHWTPTLTFYSRYS----AAHLR 476
Query: 347 ELSQILINDIAK--PTTQLNALIHKYK 371
+++ LI +A+ P +L A+ +KY+
Sbjct: 477 PITR-LIAKLARDAPQAKLKAIYNKYQ 502
>Hs14719420_2 [D] KOG0653 Cyclin B and related kinase-activating proteins
Length = 1284
Score = 124 bits (312), Expect = 2e-28
Identities = 78/252 (30%), Positives = 132/252 (51%), Gaps = 19/252 (7%)
Query: 129 DYSDDIFDHLYTRQFETTPKINYLKDKNYEFYLRP----------TMRSILVDWIIEVHC 178
D SD F+ +Y ++ +Y+K++ +F L MR+ILVDW++EV
Sbjct: 1008 DSSDPSFNPMYAKEI-----FSYMKEREEQFILTDYMNRQIEITSDMRAILVDWLVEVQV 1062
Query: 179 KFQLLPETLYLSINLMDRYLSFNKVTLPKLQLIAITSLLIAAKFEEVNLPKLSNYSYITD 238
F++ ETLYL++ L+D YL KLQL+ T+ +IAAKFEE N P++ ++ YI D
Sbjct: 1063 SFEMTHETLYLAVKLVDLYLMKAVCKKDKLQLLGATAFMIAAKFEEHNSPRVDDFVYICD 1122
Query: 239 NAYSNDEIKQAEFVILNKLEYNIGWPNPLNFLRRISRCDEYDSITRTLGKCLIGYMISCP 298
+ Y E+ E ILN L+ +I P +FLRR +RC + T TL + + +
Sbjct: 1123 DNYQRSEVLSMEINILNVLKCDINIPIAYHFLRRYARCIHTNMKTLTLSRYICEMTLQEY 1182
Query: 299 HFIDVVPSKIASVAMFTAQRIVHEDFQWDELWDYYSCFSFKDNEIELKELSQILINDIAK 358
H++ SK+A+ ++ A + + W ++YS +S + +++L+++L
Sbjct: 1183 HYVQEKASKLAAASLLLALYMKKLGY-WVPFLEHYSGYSISELHPLVRQLNKLL---TFS 1238
Query: 359 PTTQLNALIHKY 370
L A+ +KY
Sbjct: 1239 SYDSLKAVYYKY 1250
>At1g76310 [D] KOG0653 Cyclin B and related kinase-activating proteins
Length = 457
Score = 124 bits (310), Expect = 3e-28
Identities = 65/189 (34%), Positives = 115/189 (60%), Gaps = 4/189 (2%)
Query: 150 NYLKDKNYEFYLRPTMRSILVDWIIEVHCKFQLLPETLYLSINLMDRYLSFNK-VTLPKL 208
NY+++++ + MR IL DW+IEVH KF+L+ ETLYL+INL+DR+L+ ++ + KL
Sbjct: 223 NYMENQHD---INERMRGILFDWLIEVHYKFELMEETLYLTINLIDRFLAVHQHIARKKL 279
Query: 209 QLIAITSLLIAAKFEEVNLPKLSNYSYITDNAYSNDEIKQAEFVILNKLEYNIGWPNPLN 268
QL+ +T++L+A K+EEV++P + + I+D AY+ EI E ++ N L++N P P
Sbjct: 280 QLVGVTAMLLACKYEEVSVPVVDDLILISDKAYTRTEILDMEKLMANTLQFNFCLPTPYV 339
Query: 269 FLRRISRCDEYDSITRTLGKCLIGYMISCPHFIDVVPSKIASVAMFTAQRIVHEDFQWDE 328
F+RR + + D L +I + + PS++A+ A++TAQ + W +
Sbjct: 340 FMRRFLKAAQSDKKLELLSFFMIELCLVEYEMLQYTPSQLAASAIYTAQSTLKGYEDWSK 399
Query: 329 LWDYYSCFS 337
+++S ++
Sbjct: 400 TSEFHSGYT 408
>At1g47220 [D] KOG0654 G2/Mitotic-specific cyclin A
Length = 327
Score = 122 bits (305), Expect = 1e-27
Identities = 77/235 (32%), Positives = 130/235 (54%), Gaps = 18/235 (7%)
Query: 122 EDVTMCYDYSDDIFDHLYTRQFETTPKINYLKD--KNYEFYLRPTMRSILVDWIIEVHCK 179
+D MC Y DI+++L R+ E PK+ L D + + + P+ R +LVDW++EV +
Sbjct: 48 DDPQMCGLYVSDIYEYL--RELEVKPKLRPLHDYIEKIQEDITPSKRGVLVDWLVEVAEE 105
Query: 180 FQLLPETLYLSINLMDRYLSFNKVTLPKLQLIAITSLLIAAKFEEVNLPKLSNYSYITDN 239
F+L+ ETLYL+++ +DR+LS V LQL+ ++++ IA+K+EE PK+ ++ YIT N
Sbjct: 106 FELVSETLYLTVSYIDRFLSLKMVNEHWLQLVGVSAMFIASKYEEKRRPKVEDFCYITAN 165
Query: 240 AYSNDEIKQAEFVILNKLEYNIGWPNPLNFLRRISRCDEYDSITRTLGK----CLIGYM- 294
Y+ ++ + E IL LE+ +G P FLRR R + D L C + +
Sbjct: 166 TYTKQDVLKMEEDILLALEFELGRPTTNTFLRRFIRVAQEDFKVPNLQLEPLCCYLSELS 225
Query: 295 ---ISCPHFIDVVPSKIASVAMFTAQRIV-HEDFQWDELWDYYSCFSFKDNEIEL 345
SC F VPS +A+ A+F A+ I+ W ++ + C +K ++++
Sbjct: 226 MLDYSCVKF---VPSLLAASAVFLARFIILPNQHPWSQMLE--ECTKYKAADLQV 275
>At2g26760 [D] KOG0653 Cyclin B and related kinase-activating proteins
Length = 387
Score = 121 bits (304), Expect = 2e-27
Identities = 87/261 (33%), Positives = 150/261 (57%), Gaps = 19/261 (7%)
Query: 117 DSQDKEDVTMCYDYSDDIFDHLYTRQFETTPKINYLKDKNYEFYLRPTMRSILVDWIIEV 176
D+ D + +Y +DIF T + E K +Y+ + + MRSIL+DW+++V
Sbjct: 117 DAVDANNELAAVEYVEDIFKFYRTVEEEGGIK-DYIGSQPE---INEKMRSILIDWLVDV 172
Query: 177 HCKFQLLPETLYLSINLMDRYLSFNKVTLPKLQLIAITSLLIAAKFEEVNLPKLSNYSYI 236
H KF+L+PETLYL+INL+DR+LS V +LQL+ + ++LIA K+EE+ P+++++ I
Sbjct: 173 HRKFELMPETLYLTINLVDRFLSLTMVHRRELQLLGLGAMLIACKYEEIWAPEVNDFVCI 232
Query: 237 TDNAYSNDEIKQAEFVILNKLEYNIGWPNPLNFLRRISR----CD-EYDSITRTLGKCLI 291
+DNAY+ ++ E IL ++E+ I P P FL R + CD E + + L + +
Sbjct: 233 SDNAYNRKQVLAMEKSILGQVEWYITVPTPYVFLARYVKAAVPCDAEMEKLVFYLAE--L 290
Query: 292 GYMISCPHFIDVVPSKIASVAMFTAQRIVHEDFQWDELWDYYSCFSFKDNEIELKELSQI 351
G M P + PS +A+ A++ A++I+ + W E +++ +S E E+ E +++
Sbjct: 291 GLM-QYPIVVLNRPSMLAASAVYAARQILKKTPFWTETLKHHTGYS----EDEIMEHAKM 345
Query: 352 L--INDIAKPTTQLNALIHKY 370
L + D A ++L A+ KY
Sbjct: 346 LMKLRDSAS-ESKLIAVFKKY 365
>SPBC16E9.17c [D] KOG0653 Cyclin B and related kinase-activating proteins
Length = 402
Score = 119 bits (299), Expect = 6e-27
Identities = 75/307 (24%), Positives = 144/307 (46%), Gaps = 19/307 (6%)
Query: 87 DVRSDDDILEPRKSHKXXXXXXXXXXXXXXDSQDKEDVTMCY--------DYSDDIFDHL 138
DV S ++ P S + ++E++ M Y +Y+ +I H+
Sbjct: 91 DVCSISNVQSPNCSVSEFGIAIEESNDNCAEEDEEEELQMRYSADESVSVEYAKEILSHM 150
Query: 139 YTRQFETTPKINYLKDKNYEFYLRPTMRSILVDWIIEVHCKFQLLPETLYLSINLMDRYL 198
+ P ++ + Y MR+ +++WI+ VH LLPE+L+LSIN++DR+L
Sbjct: 151 EKLEIRFMPDYRHMSAQPYYV---TEMRASVINWIVGVHTCINLLPESLFLSINVLDRFL 207
Query: 199 SFNKVTLPKLQLIAITSLLIAAKFEEVNLPKLSNYSYITDNAYSNDEIKQAEFVILNKLE 258
S V K++L T+L IA K+EE++ P + + + + + ++I E +L L+
Sbjct: 208 SLQNVPASKMKLCGATALFIACKYEEIHPPTVKDLEIVLEGEWIGEDICGMEKYMLMVLQ 267
Query: 259 YNIGWPNPLNFLRRISRCDEYDSITRTLGKCLIGYMISCPHFIDVVPSKIASVAMFTAQR 318
Y +GWP P++FLR ++ ++++S R + K + + F + S++ + +T Q
Sbjct: 268 YQLGWPGPVSFLRLLTIVNKWESQLRIMIKYFLEVSLVEQRFSSLRASQLVATCAYTGQS 327
Query: 319 IVHEDFQWDELWDYYSCFSFKDNEIELKELSQILINDIAKPTTQLNALIHKYKK---IGT 375
I+ E+ W + + + + L +L+ + P A+ KY G
Sbjct: 328 ILQEE-NWSNTLPQITGYDY----MSLVSYVHLLLKCLENPFDHHYAIYSKYATPYFHGI 382
Query: 376 WNKIHDW 382
++HDW
Sbjct: 383 SRQVHDW 389
>At5g11300 [D] KOG0654 G2/Mitotic-specific cyclin A
Length = 434
Score = 119 bits (298), Expect = 8e-27
Identities = 69/242 (28%), Positives = 132/242 (54%), Gaps = 16/242 (6%)
Query: 122 EDVTMCYDYSDDIFDHLYTRQFETTPKINYLKDKNYEFYLRPTMRSILVDWIIEVHCKFQ 181
ED C Y+ DI+D+++ + + P NY++ + + P MR IL+DW++EV ++
Sbjct: 164 EDPQCCSLYAADIYDNIHVAELQQRPLANYMELVQRD--IDPDMRKILIDWLVEVSDDYK 221
Query: 182 LLPETLYLSINLMDRYLSFNKVTLPKLQLIAITSLLIAAKFEEVNLPKLSNYSYITDNAY 241
L+P+TLYL++NL+DR+LS + + +LQL+ ++ +LIA+K+EE++ P + + +IT N Y
Sbjct: 222 LVPDTLYLTVNLIDRFLSNSYIERQRLQLLGVSCMLIASKYEELSAPGVEEFCFITANTY 281
Query: 242 SNDEIKQAEFVILNKLEYNIGWPNPLNFLRRISRC-------DEYDSITRTLGK-CLIGY 293
+ E+ E ILN + + + P FL + E + + L + L+ Y
Sbjct: 282 TRPEVLSMEIQILNFVHFRLSVPTTKTFLSALFLIIILQVPFIELEYLANYLAELTLVEY 341
Query: 294 MISCPHFIDVVPSKIASVAMFTAQRIVHE-DFQWDELWDYYSCFSFKDNEIELKELSQIL 352
F+ +PS IA+ A+F A+ + + D W+ +Y+ + + + + + +
Sbjct: 342 -----SFLRFLPSLIAASAVFLARWTLDQTDHPWNPTLQHYTRYEVAELKNTVLAMEDLQ 396
Query: 353 IN 354
+N
Sbjct: 397 LN 398
>Hs4502611 [D] KOG0654 G2/Mitotic-specific cyclin A
Length = 465
Score = 118 bits (296), Expect = 1e-26
Identities = 74/253 (29%), Positives = 138/253 (54%), Gaps = 14/253 (5%)
Query: 123 DVTMCYDYSDDIFDHLYTRQFETTPKINYLKDKNYEFYLRPTMRSILVDWIIEVHCKFQL 182
DV +Y+++I+ +L + PK +Y+K + + MR+ILVDW++EV +++L
Sbjct: 204 DVINVTEYAEEIYQYLREAEIRHRPKAHYMKKQPD---ITEGMRTILVDWLVEVGEEYKL 260
Query: 183 LPETLYLSINLMDRYLSFNKVTLPKLQLIAITSLLIAAKFEEVNLPKLSNYSYITDNAYS 242
ETLYL++N +DR+LS V KLQL+ ++L+A+K+EE+ P++ + YITD+ Y+
Sbjct: 261 RAETLYLAVNFLDRFLSCMSVLRGKLQLVGTAAMLLASKYEEIYPPEVDEFVYITDDTYT 320
Query: 243 NDEIKQAEFVILNKLEYNIGWPNP----LNFLRRISRCDEYDSITRTLGKCLIGYMISCP 298
++ + E ++L L +++ P L +LRR C +++ + + + ++
Sbjct: 321 KRQLLKMEHLLLKVLAFDLTVPTTNQFLLQYLRRQGVCVRTENLAKYVAEL---SLLEAD 377
Query: 299 HFIDVVPSKIASVAMFTAQRIVHEDFQWDELWDYYSCFSFKDNEIELKELSQILINDIAK 358
F+ +PS IA+ A A V++ F W E ++ +S + L EL + ++ +
Sbjct: 378 PFLKYLPSLIAAAAFCLANYTVNKHF-WPETLAAFTGYSLSEIVPCLSELHKAYLDIPHR 436
Query: 359 PTTQLNALIHKYK 371
P A+ KYK
Sbjct: 437 PQ---QAIREKYK 446
>CE06570 [D] KOG0653 Cyclin B and related kinase-activating proteins
Length = 361
Score = 114 bits (284), Expect = 3e-25
Identities = 75/213 (35%), Positives = 114/213 (53%), Gaps = 20/213 (9%)
Query: 119 QDKEDVTMCYDYSDDIFDHLYTRQFETTPKINYLKDKNYEFYLRPT--MRSILVDWIIEV 176
QD E T C +DDI+ +L + + YL ++ + PT MR ILVDW+++V
Sbjct: 69 QDAE--TKCLAMADDIYKYLVHHEKK------YLLEECFMEGGEPTPKMRRILVDWLVQV 120
Query: 177 HCKFQLLPETLYLSINLMDRYLSFNKVTLPKLQLIAITSLLIAAKFEEVNLPKLSNYSYI 236
H +F L PETL+L++ ++DR L + LQL+ I+++ +A+KFEEV LP + +Y +I
Sbjct: 121 HVRFHLTPETLHLTVFILDRMLQKKVTSKADLQLLGISAMFVASKFEEVYLPDIHDYEFI 180
Query: 237 TDNAYSNDEIKQAEFVILNKLEYNIGWPNPLNFLRRISR-CDEYDS---------ITRTL 286
T+N YS +I E ILN L +++ P+ L FLR +SR E D+ T +
Sbjct: 181 TENTYSKKQILAMEQTILNSLNFDLSCPSSLVFLRCLSRILSENDASPIDNQAFCYTYNI 240
Query: 287 GKCLIGYMISCPHFIDVVPSKIASVAMFTAQRI 319
KCL + S IAS +M A +
Sbjct: 241 SKCLGELALLDSVMASTPRSHIASASMIIALEV 273
>CE28122 [D] KOG0653 Cyclin B and related kinase-activating proteins
Length = 317
Score = 113 bits (282), Expect = 6e-25
Identities = 68/213 (31%), Positives = 114/213 (52%), Gaps = 16/213 (7%)
Query: 122 EDVTMCYDYSDDIFDHLYTRQFETTPKINYLKDKNYEFYLRPTMRSILVDWIIEVHCKFQ 181
E+V C ++DI+++L + + +++ N + MR ILVDW+I+VH +F
Sbjct: 23 EEVLNCIAMAEDIYNYLVHHEKKYVLDDSFINGGN----VNSKMRRILVDWLIQVHLRFH 78
Query: 182 LLPETLYLSINLMDRYLSFNKVTLPKLQLIAITSLLIAAKFEEVNLPKLSNYSYITDNAY 241
L PETL+L+I ++DR + N V+ + QL+ + +L +A+KFE++ LP + Y ITDN +
Sbjct: 79 LTPETLHLTIFVLDRIIVKNIVSKAEFQLLGVAALFVASKFEDIYLPDILEYEMITDNTF 138
Query: 242 SNDEIKQAEFVILNKLEYNIGWPNPLNFLRRISRCDEYDSI----------TRTLGKCLI 291
S +I E ILN L +++ P+ L FLR IS+ + + + KCL
Sbjct: 139 SKKQIMAMEQTILNALNFDLSCPSSLVFLRCISKTLTENDVNPIDKEAFYYVHNISKCL- 197
Query: 292 GYMISCPHFIDVVP-SKIASVAMFTAQRIVHED 323
G + + VP S +AS +M ++ D
Sbjct: 198 GELALLDSVMSTVPRSHVASASMIITLNVITVD 230
>At4g37490 [D] KOG0653 Cyclin B and related kinase-activating proteins
Length = 428
Score = 108 bits (270), Expect = 1e-23
Identities = 71/241 (29%), Positives = 135/241 (55%), Gaps = 17/241 (7%)
Query: 117 DSQDKEDVTMCYDYSDDIFDHLYTRQFETTPKINYLKDKNYEFYLRPTMRSILVDWIIEV 176
DS D E+ +Y +DI+ + + E P+ +Y+ + + MR ILV+W+I+V
Sbjct: 152 DSADVENDLAAVEYVEDIYSFYKSVESEWRPR-DYMASQPD---INEKMRLILVEWLIDV 207
Query: 177 HCKFQLLPETLYLSINLMDRYLSFNKVTLPKLQLIAITSLLIAAKFEEVNLPKLSNYSYI 236
H +F+L PET YL++N++DR+LS V +LQL+ +++LL++AK+EE+ P++ + I
Sbjct: 208 HVRFELNPETFYLTVNILDRFLSVKPVPRKELQLVGLSALLMSAKYEEIWPPQVEDLVDI 267
Query: 237 TDNAYSNDEIKQAEFVILNKLEYNIGWPNPLNFLRRISRCDEYDSITRTLGKCLIGYM-- 294
D+AYS+ +I E IL+ LE+ + P FL R + SI + ++ Y+
Sbjct: 268 ADHAYSHKQILVMEKTILSTLEWYLTVPTHYVFLARFIKA----SIADEKMENMVHYLAE 323
Query: 295 ISCPHFIDVV---PSKIASVAMFTAQRIVHEDFQWDELWDYYSCFSFKDNEIELKELSQI 351
+ H+ ++ PS +A+ A++ A+ + + W +++ +S E +L + +++
Sbjct: 324 LGVMHYDTMIMFSPSMVAASAIYAARSSLRQVPIWTSTLKHHTGYS----ETQLMDCAKL 379
Query: 352 L 352
L
Sbjct: 380 L 380
>Hs4502613 [D] KOG0654 G2/Mitotic-specific cyclin A
Length = 432
Score = 107 bits (268), Expect = 2e-23
Identities = 62/194 (31%), Positives = 113/194 (57%), Gaps = 13/194 (6%)
Query: 129 DYSDDIFDHLYTRQFETTPKINYLKDKNYEFYLRPTMRSILVDWIIEVHCKFQLLPETLY 188
DY +DI +L + + PK+ Y+K + + +MR+ILVDW++EV +++L ETL+
Sbjct: 177 DYHEDIHTYLREMEVKCKPKVGYMKKQPD---ITNSMRAILVDWLVEVGEEYKLQNETLH 233
Query: 189 LSINLMDRYLSFNKVTLPKLQLIAITSLLIAAKFEEVNLPKLSNYSYITDNAYSNDEIKQ 248
L++N +DR+LS V KLQL+ ++L+A+KFEE+ P+++ + YITD+ Y+ ++ +
Sbjct: 234 LAVNYIDRFLSSMSVLRGKLQLVGTAAMLLASKFEEIYPPEVAEFVYITDDTYTKKQVLR 293
Query: 249 AEFVILNKLEYNIGWPNPLNFL------RRISRCDEYDSITRTLGKCLIGYMISCPHFID 302
E ++L L +++ P FL ++ + C + +S+ LG+ +I ++
Sbjct: 294 MEHLVLKVLTFDLAAPTVNQFLTQYFLHQQPANC-KVESLAMFLGEL---SLIDADPYLK 349
Query: 303 VVPSKIASVAMFTA 316
+PS IA A A
Sbjct: 350 YLPSVIAGAAFHLA 363
>CE23835 [D] KOG0653 Cyclin B and related kinase-activating proteins
Length = 339
Score = 107 bits (266), Expect = 4e-23
Identities = 64/204 (31%), Positives = 110/204 (53%), Gaps = 16/204 (7%)
Query: 131 SDDIFDHLYTRQFETTPKINYLKDKNYEFYLRPTMRSILVDWIIEVHCKFQLLPETLYLS 190
++DI+++L + + +++ N + MR ILVDW+++VH +F L PETL+L+
Sbjct: 54 AEDIYNYLVHHEKKYVLDDSFINGGN----VNSKMRRILVDWLVQVHLRFHLTPETLHLT 109
Query: 191 INLMDRYLSFNKVTLPKLQLIAITSLLIAAKFEEVNLPKLSNYSYITDNAYSNDEIKQAE 250
I ++DR + N V+ + QL+ + +L +A+KFE++ LP + Y IT+N +S +I E
Sbjct: 110 IFVLDRIIVKNIVSKAEFQLLGVAALFVASKFEDIYLPDILEYELITENTFSKKQILAME 169
Query: 251 FVILNKLEYNIGWPNPLNFLRRISRCDEYDSI----------TRTLGKCLIGYMISCPHF 300
ILN L +++ P+ L FLR IS+ + + + KCL G +
Sbjct: 170 QTILNALNFDLSCPSSLVFLRYISKTLTENDVNPIDKETFYYVHNISKCL-GELALLDSV 228
Query: 301 IDVVP-SKIASVAMFTAQRIVHED 323
+ VP S +AS +M I+ D
Sbjct: 229 MSTVPRSHVASASMIITLNIISVD 252
>At1g16330 [D] KOG0653 Cyclin B and related kinase-activating proteins
Length = 518
Score = 106 bits (265), Expect = 5e-23
Identities = 68/243 (27%), Positives = 128/243 (51%), Gaps = 8/243 (3%)
Query: 129 DYSDDIFDHLYTRQFETTPKINYLKDKNYEFYLRPTMRSILVDWIIEVHCKFQLLPETLY 188
+Y DDI+ +T + P + + + E + P R IL++W+IEVH KF L+ ETLY
Sbjct: 264 EYVDDIYQFYWTAE-ALNPALGHYLSAHAE--VSPVTRGILINWLIEVHFKFDLMHETLY 320
Query: 189 LSINLMDRYLSFNKVTLPKLQLIAITSLLIAAKFEEVNLPKLSNYSYITDNAYSNDEIKQ 248
L+++L+DRYLS + ++QLI +T+LL+A+K+E+ P++ + I+ +Y+ ++I
Sbjct: 321 LTMDLLDRYLSQVPIHKNEMQLIGLTALLLASKYEDYWHPRIKDLISISAESYTREQILG 380
Query: 249 AEFVILNKLEYNIGWPNPLNFLRRISRCDEYDSITRTLGKCLIGYMISCPHFIDVVPSKI 308
E +L +L++ + P P F+ R + + + L LI + + PS +
Sbjct: 381 MERSMLKQLKFRLNAPTPYVFMLRFLKAAQSNKKLEQLAFYLIELCLVEYEALKYKPSLL 440
Query: 309 ASVAMFTAQRIVHEDFQWDELWDYYSCFSFKDNEIELKELSQILIN-DIAKPTTQLNALI 367
+ A++ A+ +H W L + ++ + N ++K+ S +++ A T L
Sbjct: 441 CASAIYVARCTLHMTPVWTSLLNNHTHY----NVSQMKDCSDMILRFHKAAKTGNLRVTY 496
Query: 368 HKY 370
KY
Sbjct: 497 EKY 499
>CE27776 [D] KOG0653 Cyclin B and related kinase-activating proteins
Length = 383
Score = 99.4 bits (246), Expect = 9e-21
Identities = 64/227 (28%), Positives = 122/227 (53%), Gaps = 7/227 (3%)
Query: 129 DYSDDIFDHLYTRQFETTPKINYLKDKNYEFYLRPTMRSILVDWIIEVHCKFQLLPETLY 188
DY+ IFD Y R E ++ K+ E ++ R+IL+DW++E+ F+L ETLY
Sbjct: 109 DYAQGIFD--YYRHREVHFRVRKYLHKHPEVDVKT--RAILIDWMVEIQETFELNHETLY 164
Query: 189 LSINLMDRYLSFNK-VTLPKLQLIAITSLLIAAKFEEVNLPKLSNYSYITDNAYSNDEIK 247
++ L D YL K V +Q +A ++ IAAK++E + P + + Y++ + +S DE+
Sbjct: 165 NAVKLTDMYLCKTKNVDKNTIQKLACVAIFIAAKYDERSPPLVDDLIYLSGDRFSRDELL 224
Query: 248 QAEFVILNKLEYNIGWPNPLNFLRRISRCDEYDSITRTLGKCLIGYMISCPHFIDVVPSK 307
E + + Y++G P +LRR R D T T+G+ ++ + + V S+
Sbjct: 225 AMERELFATVGYDLGSPLSYRYLRRFGRVCRVDMKTLTMGRFILETSLMVYEYAMVSQSR 284
Query: 308 IASVAMFTAQRIV--HEDFQWDELWDYYSCFSFKDNEIELKELSQIL 352
+A+ A A R++ + +++W+ + + YS F+ ++ ++ ++ IL
Sbjct: 285 LAAAAFVLAMRMLDKNNEYEWNPVLEKYSGFTGEEVMPLVEHMNHIL 331
>CE13315 [D] KOG0653 Cyclin B and related kinase-activating proteins
Length = 384
Score = 99.4 bits (246), Expect = 9e-21
Identities = 64/227 (28%), Positives = 122/227 (53%), Gaps = 7/227 (3%)
Query: 129 DYSDDIFDHLYTRQFETTPKINYLKDKNYEFYLRPTMRSILVDWIIEVHCKFQLLPETLY 188
DY+ IFD Y R E ++ K+ E ++ R+IL+DW++E+ F+L ETLY
Sbjct: 110 DYAQGIFD--YYRHREVHFRVRKYLHKHPEVDVKT--RAILIDWMVEIQETFELNHETLY 165
Query: 189 LSINLMDRYLSFNK-VTLPKLQLIAITSLLIAAKFEEVNLPKLSNYSYITDNAYSNDEIK 247
++ L D YL K V +Q +A ++ IAAK++E + P + + Y++ + +S DE+
Sbjct: 166 NAVKLTDMYLCKTKNVDKNTIQKLACVAIFIAAKYDERSPPLVDDLIYLSGDRFSRDELL 225
Query: 248 QAEFVILNKLEYNIGWPNPLNFLRRISRCDEYDSITRTLGKCLIGYMISCPHFIDVVPSK 307
E + + Y++G P +LRR R D T T+G+ ++ + + V S+
Sbjct: 226 AMERELFATVGYDLGSPLSYRYLRRFGRVCRVDMKTLTMGRFILETSLMVYEYAMVSQSR 285
Query: 308 IASVAMFTAQRIV--HEDFQWDELWDYYSCFSFKDNEIELKELSQIL 352
+A+ A A R++ + +++W+ + + YS F+ ++ ++ ++ IL
Sbjct: 286 LAAAAFVLAMRMLDKNNEYEWNPVLEKYSGFTGEEVMPLVEHMNHIL 332
>Hs16306525_2 [D] KOG0653 Cyclin B and related kinase-activating proteins
Length = 221
Score = 97.8 bits (242), Expect = 3e-20
Identities = 60/191 (31%), Positives = 102/191 (52%), Gaps = 4/191 (2%)
Query: 180 FQLLPETLYLSINLMDRYLSFNKVTLPKLQLIAITSLLIAAKFEEVNLPKLSNYSYITDN 239
F++ ETLYL++ L+D YL KLQL+ T+ +IAAKFEE N P++ ++ YI D+
Sbjct: 1 FEMTHETLYLAVKLVDLYLMKAVCKKDKLQLLGATAFMIAAKFEEHNSPRVDDFVYICDD 60
Query: 240 AYSNDEIKQAEFVILNKLEYNIGWPNPLNFLRRISRCDEYDSITRTLGKCLIGYMISCPH 299
Y E+ E ILN L+ +I P +FLRR +RC + T TL + + + H
Sbjct: 61 NYQRSEVLSMEINILNVLKCDINIPIAYHFLRRYARCIHTNMKTLTLSRYICEMTLQEYH 120
Query: 300 FIDVVPSKIASVAMFTAQRIVHEDFQWDELWDYYSCFSFKDNEIELKELSQILINDIAKP 359
++ SK+A+ ++ A + + W ++YS +S + +++L+++L
Sbjct: 121 YVQEKASKLAAASLLLALYMKKLGY-WVPFLEHYSGYSISELHPLVRQLNKLL---TFSS 176
Query: 360 TTQLNALIHKY 370
L A+ +KY
Sbjct: 177 YDSLKAVYYKY 187
>7294661 [D] KOG0654 G2/Mitotic-specific cyclin A
Length = 490
Score = 92.4 bits (228), Expect = 1e-18
Identities = 56/202 (27%), Positives = 109/202 (53%), Gaps = 4/202 (1%)
Query: 120 DKEDVTMCYDYSDDIFDHLYTRQFETTPKINYLKDKNYEFYLRPTMRSILVDWIIEVHCK 179
D++ Y DI ++ + + PK Y++ + + MRSIL+DW++EV +
Sbjct: 192 DRQRFLEVVQYQMDILEYFRESEKKHRPKPLYMRRQKD---ISHNMRSILIDWLVEVSEE 248
Query: 180 FQLLPETLYLSINLMDRYLSFNKVTLPKLQLIAITSLLIAAKFEEVNLPKLSNYSYITDN 239
++L ETLYLS+ +DR+LS V KLQL+ ++ IAAK+EE+ P++ + ++TD+
Sbjct: 249 YKLDTETLYLSVFYLDRFLSQMAVVRSKLQLVGTAAMYIAAKYEEIYPPEVGEFVFLTDD 308
Query: 240 AYSNDEIKQAEFVILNKLEYNIGWPNPLNFLRRIS-RCDEYDSITRTLGKCLIGYMISCP 298
+Y+ ++ + E VIL L +++ P F+ + CD + + ++
Sbjct: 309 SYTKAQVLRMEQVILKILSFDLCTPTAYVFINTYAVLCDMPEKLKYMTLYISELSLMEGE 368
Query: 299 HFIDVVPSKIASVAMFTAQRIV 320
++ +PS ++S ++ A+ I+
Sbjct: 369 TYLQYLPSLMSSASVALARHIL 390
>Hs17318567 [D] KOG0655 G1/S-specific cyclin E
Length = 296
Score = 90.9 bits (224), Expect = 3e-18
Identities = 49/115 (42%), Positives = 73/115 (62%), Gaps = 4/115 (3%)
Query: 151 YLKDKNYEFY---LRPTMRSILVDWIIEVHCKFQLLPETLYLSINLMDRYLSFNK-VTLP 206
Y+ DK++E L P MRSIL+DW++EV + L ET YL+ + DR++ K +
Sbjct: 16 YVHDKHFEVLHSDLEPQMRSILLDWLLEVCEVYTLHRETFYLAQDFFDRFMLTQKDINKN 75
Query: 207 KLQLIAITSLLIAAKFEEVNLPKLSNYSYITDNAYSNDEIKQAEFVILNKLEYNI 261
LQLI ITSL IA+K EE+ PKL ++Y+TD A S ++I + E +IL L++ +
Sbjct: 76 MLQLIGITSLFIASKLEEIYAPKLQEFAYVTDGACSEEDILRMELIILKALKWEL 130
>Hs17318565 [D] KOG0655 G1/S-specific cyclin E
Length = 404
Score = 90.9 bits (224), Expect = 3e-18
Identities = 49/115 (42%), Positives = 73/115 (62%), Gaps = 4/115 (3%)
Query: 151 YLKDKNYEFY---LRPTMRSILVDWIIEVHCKFQLLPETLYLSINLMDRYLSFNK-VTLP 206
Y+ DK++E L P MRSIL+DW++EV + L ET YL+ + DR++ K +
Sbjct: 124 YVHDKHFEVLHSDLEPQMRSILLDWLLEVCEVYTLHRETFYLAQDFFDRFMLTQKDINKN 183
Query: 207 KLQLIAITSLLIAAKFEEVNLPKLSNYSYITDNAYSNDEIKQAEFVILNKLEYNI 261
LQLI ITSL IA+K EE+ PKL ++Y+TD A S ++I + E +IL L++ +
Sbjct: 184 MLQLIGITSLFIASKLEEIYAPKLQEFAYVTDGACSEEDILRMELIILKALKWEL 238
>Hs17318561 [D] KOG0655 G1/S-specific cyclin E
Length = 395
Score = 88.6 bits (218), Expect = 2e-17
Identities = 49/115 (42%), Positives = 75/115 (64%), Gaps = 4/115 (3%)
Query: 151 YLKDKNY---EFYLRPTMRSILVDWIIEVHCKFQLLPETLYLSINLMDRYLSFNK-VTLP 206
YL+D+++ L+P MR+IL+DW++EV ++L ET YL+ + DRY++ + V
Sbjct: 112 YLRDQHFLEQHPLLQPKMRAILLDWLMEVCEVYKLHRETFYLAQDFFDRYMATQENVVKT 171
Query: 207 KLQLIAITSLLIAAKFEEVNLPKLSNYSYITDNAYSNDEIKQAEFVILNKLEYNI 261
LQLI I+SL IAAK EE+ PKL ++Y+TD A S DEI E +I+ L++ +
Sbjct: 172 LLQLIGISSLFIAAKLEEIYPPKLHQFAYVTDGACSGDEILTMELMIMKALKWRL 226
>Hs17318559 [D] KOG0655 G1/S-specific cyclin E
Length = 410
Score = 88.6 bits (218), Expect = 2e-17
Identities = 49/115 (42%), Positives = 75/115 (64%), Gaps = 4/115 (3%)
Query: 151 YLKDKNY---EFYLRPTMRSILVDWIIEVHCKFQLLPETLYLSINLMDRYLSFNK-VTLP 206
YL+D+++ L+P MR+IL+DW++EV ++L ET YL+ + DRY++ + V
Sbjct: 127 YLRDQHFLEQHPLLQPKMRAILLDWLMEVCEVYKLHRETFYLAQDFFDRYMATQENVVKT 186
Query: 207 KLQLIAITSLLIAAKFEEVNLPKLSNYSYITDNAYSNDEIKQAEFVILNKLEYNI 261
LQLI I+SL IAAK EE+ PKL ++Y+TD A S DEI E +I+ L++ +
Sbjct: 187 LLQLIGISSLFIAAKLEEIYPPKLHQFAYVTDGACSGDEILTMELMIMKALKWRL 241
>7298245 [D] KOG0655 G1/S-specific cyclin E
Length = 709
Score = 87.0 bits (214), Expect = 4e-17
Identities = 45/102 (44%), Positives = 69/102 (67%), Gaps = 1/102 (0%)
Query: 161 LRPTMRSILVDWIIEVHCKFQLLPETLYLSINLMDRYLSF-NKVTLPKLQLIAITSLLIA 219
L+P MR+IL+DW+IEV ++L ET YL+++ +DRYL +KV LQLI IT L +A
Sbjct: 357 LQPRMRAILLDWLIEVCEVYKLHRETFYLAVDYLDRYLHVAHKVQKTHLQLIGITCLFVA 416
Query: 220 AKFEEVNLPKLSNYSYITDNAYSNDEIKQAEFVILNKLEYNI 261
AK EE+ PK+ ++Y+TD A + +I E ++L L+++I
Sbjct: 417 AKVEEIYPPKIGEFAYVTDGACTERDILNHEKILLQALDWDI 458
>Hs22048740 [D] KOG0655 G1/S-specific cyclin E
Length = 148
Score = 82.8 bits (203), Expect = 8e-16
Identities = 43/98 (43%), Positives = 64/98 (64%), Gaps = 1/98 (1%)
Query: 165 MRSILVDWIIEVHCKFQLLPETLYLSINLMDRYLSFNK-VTLPKLQLIAITSLLIAAKFE 223
MRSIL+DW++EV + L ET YL+ + DR++ K + LQLI ITSL IA+K E
Sbjct: 1 MRSILLDWLLEVCEVYTLHRETFYLAQDFFDRFMLTQKDINKNMLQLIGITSLFIASKLE 60
Query: 224 EVNLPKLSNYSYITDNAYSNDEIKQAEFVILNKLEYNI 261
E+ PKL ++Y+TD A S ++I + E +IL L++ +
Sbjct: 61 EIYAPKLQEFAYVTDGACSEEDILRMELIILKALKWEL 98
>At1g20590 [D] KOG0653 Cyclin B and related kinase-activating proteins
Length = 199
Score = 82.8 bits (203), Expect = 8e-16
Identities = 40/141 (28%), Positives = 82/141 (57%)
Query: 197 YLSFNKVTLPKLQLIAITSLLIAAKFEEVNLPKLSNYSYITDNAYSNDEIKQAEFVILNK 256
+L+ +++ KLQL+ +T+LL+A K+EEV++P + + I+D AYS E+ E ++ N
Sbjct: 3 FLAVHQIVRKKLQLVGVTALLLACKYEEVSVPVVDDLILISDKAYSRREVLDMEKLMANT 62
Query: 257 LEYNIGWPNPLNFLRRISRCDEYDSITRTLGKCLIGYMISCPHFIDVVPSKIASVAMFTA 316
L++N P P F++R + + D L +I + ++ +PSK+A+ A++TA
Sbjct: 63 LQFNFSLPTPYVFMKRFLKAAQSDKKLEILSFFMIELCLVEYEMLEYLPSKLAASAIYTA 122
Query: 317 QRIVHEDFQWDELWDYYSCFS 337
Q + +W + ++++ ++
Sbjct: 123 QCTLKGFEEWSKTCEFHTGYN 143
>CE03820 [D] KOG0654 G2/Mitotic-specific cyclin A
Length = 485
Score = 81.6 bits (200), Expect = 2e-15
Identities = 45/148 (30%), Positives = 79/148 (52%)
Query: 165 MRSILVDWIIEVHCKFQLLPETLYLSINLMDRYLSFNKVTLPKLQLIAITSLLIAAKFEE 224
MR+IL+DW +V ++ ET +L+++L+DR LS + + QL+ TS++IA K+EE
Sbjct: 244 MRTILIDWFSDVVKEYNFQKETFHLAVSLVDRALSMFNIDKMRFQLVGTTSMMIAVKYEE 303
Query: 225 VNLPKLSNYSYITDNAYSNDEIKQAEFVILNKLEYNIGWPNPLNFLRRISRCDEYDSITR 284
+ P++ +++ ITDN Y +I E +L K ++ + P F ++ + R
Sbjct: 304 IFPPEIEDFALITDNTYRVPDILLMERFLLGKFDFVVAMPTSSWFGTCFAKRMNFTKKMR 363
Query: 285 TLGKCLIGYMISCPHFIDVVPSKIASVA 312
L+ + HF+ PS IA+ A
Sbjct: 364 NTVHYLLELSLIDVHFLRYRPSDIAAAA 391
>SPBC19F5.01c [D] KOG0653 Cyclin B and related kinase-activating proteins
Length = 359
Score = 80.1 bits (196), Expect = 5e-15
Identities = 51/144 (35%), Positives = 78/144 (53%), Gaps = 5/144 (3%)
Query: 129 DYSDDIFDHLYTRQFETTPKINYLKDKNYEFYLRPTMRSILVDWIIEVHCKFQLLPETLY 188
+Y +DI HL TR+ ++ N + LR +MR LV++I+E+H F L +TL
Sbjct: 95 EYQEDIIHHLITREKNFLLNVHL---SNQQPELRWSMRPALVNFIVEIHNGFDLSIDTLP 151
Query: 189 LSINLMDRYLSFNKVTLPKLQLIAITSLLIAAKFEEV--NLPKLSNYSYITDNAYSNDEI 246
LSI+LMD Y+S V +QL+A L IA+KF E +P L N Y+ D
Sbjct: 152 LSISLMDSYVSRRVVYCKHIQLVACVCLWIASKFHETEDRVPLLQELKLACKNIYAEDLF 211
Query: 247 KQAEFVILNKLEYNIGWPNPLNFL 270
+ E IL+ L+++I P P +++
Sbjct: 212 IRMERHILDTLDWDISIPTPASYI 235
>At1g34460_1 [D] KOG0653 Cyclin B and related kinase-activating proteins
Length = 399
Score = 79.7 bits (195), Expect = 7e-15
Identities = 50/154 (32%), Positives = 83/154 (53%), Gaps = 24/154 (15%)
Query: 117 DSQDKEDVTMCYDYSDDIFDHLYTRQFETTPKINYLKDKNYEFYLRPTMRSILVDWIIEV 176
D DK++ +Y DD++ + E+ PK+ Y+ + + + MR+IL+DW++EV
Sbjct: 259 DESDKDNHVAAVEYVDDMYSFYKEVEKESQPKM-YM---HIQTEMNEKMRAILIDWLLEV 314
Query: 177 HCKFQLLPETLYLSINLMDRYLSFNKVTLPKLQLIAITSLLIAAKFEEVNLPKLSNYSYI 236
H KF+L ETLYL++N++DR+L V PK +L ++++ Y+
Sbjct: 315 HIKFELNLETLYLTVNIIDRFLYVKAV--PKREL------------------QVNDLVYV 354
Query: 237 TDNAYSNDEIKQAEFVILNKLEYNIGWPNPLNFL 270
TDNAYS+ +I + IL LE+ + P FL
Sbjct: 355 TDNAYSSRQILVMKKAILGNLEWYLTIPTQYVFL 388
>Hs16950655 [D] KOG0656 G1/S-specific cyclin D
Length = 295
Score = 77.0 bits (188), Expect = 5e-14
Identities = 50/175 (28%), Positives = 90/175 (50%), Gaps = 8/175 (4%)
Query: 147 PKINYLKDKNYEFYLRPTMRSILVDWIIEVHCKFQLLPETLY-LSINLMDRYLSFNKVTL 205
P ++Y K E + P+MR I+ W++EV C+ Q E ++ L++N +DR+LS V
Sbjct: 40 PSVSYFKCVQKE--VLPSMRKIVATWMLEV-CEEQKCEEEVFPLAMNYLDRFLSLEPVKK 96
Query: 206 PKLQLIAITSLLIAAKFEEVNLPKLSNYSYITDNAYSNDEIKQAEFVILNKLEYNIGWPN 265
+LQL+ T + +A+K +E TDN+ +E+ Q E +++NKL++N+
Sbjct: 97 SRLQLLGATCMFVASKMKETIPLTAEKLCIYTDNSIRPEELLQMELLLVNKLKWNLAAMT 156
Query: 266 P----LNFLRRISRCDEYDSITRTLGKCLIGYMISCPHFIDVVPSKIASVAMFTA 316
P +FL ++ +E I R + + + FI PS +A+ ++ A
Sbjct: 157 PHDFIEHFLSKMPEAEENKQIIRKHAQTFVALCATDVKFISNPPSMVAAGSVVAA 211
>HsM4502615 [D] KOG0656 G1/S-specific cyclin D
Length = 295
Score = 74.7 bits (182), Expect = 2e-13
Identities = 50/175 (28%), Positives = 92/175 (52%), Gaps = 8/175 (4%)
Query: 147 PKINYLKDKNYEFYLRPTMRSILVDWIIEVHCKFQLLPETLY-LSINLMDRYLSFNKVTL 205
P ++Y K E + P+MR I+ W++EV C+ Q E ++ L++N +DR+LS V
Sbjct: 40 PSVSYFKCVQKE--VLPSMRKIVATWMLEV-CEEQKCEEEVFPLAMNYLDRFLSLEPVKK 96
Query: 206 PKLQLIAITSLLIAAKFEEVNLPKLSNYSYITDNAYSNDEIKQAEFVILNKLEYNIGWPN 265
+LQL+ T + +A+K +E TD + +E+ Q E +++NKL++N+
Sbjct: 97 SRLQLLGATCMFVASKMKETIPLTAEKLCIYTDGSIRPEELLQMELLLVNKLKWNLAAMT 156
Query: 266 PLNFLRR-ISRCDEYDSITRTLGKCLIGYMISCP---HFIDVVPSKIASVAMFTA 316
P +F+ +S+ E + + + K ++ SC FI PS +A+ ++ A
Sbjct: 157 PHDFIEHFLSKMPEAEENKQIIRKHAQTFVASCATDVKFISNPPSMVAAGSVVAA 211
>CE24832 [D] KOG0655 G1/S-specific cyclin E
Length = 524
Score = 71.2 bits (173), Expect = 3e-12
Identities = 35/99 (35%), Positives = 65/99 (65%), Gaps = 2/99 (2%)
Query: 166 RSILVDWIIEVHCKFQLLPETLYLSINLMDRYLSFNKV--TLPKLQLIAITSLLIAAKFE 223
R IL+DW++EV +L ET +L+++ +DRYL + V + QL+ +L IAAK+E
Sbjct: 262 RRILIDWMMEVCESEKLHRETFHLAVDYVDRYLESSNVECSTDNFQLVGTAALFIAAKYE 321
Query: 224 EVNLPKLSNYSYITDNAYSNDEIKQAEFVILNKLEYNIG 262
E+ PK +++++TD+A++ D I+ E +I+ + +++G
Sbjct: 322 EIYPPKCIDFAHLTDSAFTCDNIRTMEVLIVKYIGWSLG 360
>Hs4502621 [D] KOG0654 G2/Mitotic-specific cyclin A
Length = 786
Score = 67.0 bits (162), Expect = 5e-11
Identities = 49/182 (26%), Positives = 88/182 (47%), Gaps = 4/182 (2%)
Query: 161 LRPTMRSILVDWIIEVHCKFQLLPETLYLSINLMDRYLSFNKVTLPKLQLIAITSLLIAA 220
L TMR IL+DW++EV L+L++ +DRYL V +LQL+ I ++I
Sbjct: 305 LNDTMRYILIDWLVEVATMNDFTSLCLHLTVECVDRYLRRRLVPRYRLQLLGIACMVICT 364
Query: 221 KFEEVNLPKLSNYSYITDNAYSNDEIKQAEFVILNKLEYNIGWPNPLNFLRRISRCDEYD 280
+F + + ++TDN Y +++ + I++ LE I P +++ + +
Sbjct: 365 RFISKEILTIREAVWLTDNTYKYEDLVRMMGEIVSALEGKIRVPTVVDYKEVLLTLVPVE 424
Query: 281 SITRTLGKCLIGYMISCPHFIDVVPSKIASVAMFTAQRIVHEDFQ-W-DELWDYYSCFSF 338
T+ L L + P+++A+ A+ A R+ H Q W +LWD + FS+
Sbjct: 425 LRTQHLCSFLCELSLLHTSLSAYAPARLAAAALLLA-RLTHGQTQPWTTQLWD-LTGFSY 482
Query: 339 KD 340
+D
Sbjct: 483 ED 484
>7293153 [D] KOG0656 G1/S-specific cyclin D
Length = 481
Score = 67.0 bits (162), Expect = 5e-11
Identities = 37/112 (33%), Positives = 65/112 (58%), Gaps = 2/112 (1%)
Query: 161 LRPTMRSILVDWIIEVHCKFQLLPETLYLSINLMDRYLSFNKVTLPKLQLIAITSLLIAA 220
+ P MR I+ +W++EV + E + L++N MDR+LS V +LQ++A LL+A+
Sbjct: 181 ITPPMRKIVAEWMMEVCAEENCQEEVVLLALNYMDRFLSSKSVRKTQLQILAAACLLLAS 240
Query: 221 KFEEVNLPKLSNYSYI--TDNAYSNDEIKQAEFVILNKLEYNIGWPNPLNFL 270
K E + LS + TDN+ D++ + E +L++L +++ PL+FL
Sbjct: 241 KLREPSCRALSVDLLVVYTDNSIYKDDLIKWELYVLSRLGWDLSSVTPLDFL 292
>Hs4502617 [D] KOG0656 G1/S-specific cyclin D
Length = 289
Score = 65.1 bits (157), Expect = 2e-10
Identities = 49/184 (26%), Positives = 90/184 (48%), Gaps = 8/184 (4%)
Query: 132 DDIFDHLYTRQFETTPKINYLKDKNYEFYLRPTMRSILVDWIIEVHCKFQLLPETLY-LS 190
D + +L T + P+ +Y K + ++P MR ++ W++EV C+ Q E ++ L+
Sbjct: 24 DRVLQNLLTIEERYLPQCSYFKCVQKD--IQPYMRRMVATWMLEV-CEEQKCEEEVFPLA 80
Query: 191 INLMDRYLSFNKVTLPKLQLIAITSLLIAAKFEEVNLPKLSNYSYITDNAYSNDEIKQAE 250
+N +DR+L+ LQL+ + +A+K +E + TDN+ E+ + E
Sbjct: 81 MNYLDRFLAGVPTPKSHLQLLGAVCMFLASKLKETSPLTAEKLCIYTDNSIKPQELLEWE 140
Query: 251 FVILNKLEYNIGWPNPLNF----LRRISRCDEYDSITRTLGKCLIGYMISCPHFIDVVPS 306
V+L KL++N+ P +F LR++ + E S+ R + I + F PS
Sbjct: 141 LVVLGKLKWNLAAVTPHDFIEHILRKLPQQREKLSLIRKHAQTFIALCATDFKFAMYPPS 200
Query: 307 KIAS 310
IA+
Sbjct: 201 MIAT 204
>Hs5802992 [D] KOG0653 Cyclin B and related kinase-activating proteins
Length = 377
Score = 60.1 bits (144), Expect = 6e-09
Identities = 36/110 (32%), Positives = 62/110 (55%), Gaps = 2/110 (1%)
Query: 163 PTMRSILVDWIIEVHCKFQLLPETLYLSINLMDRYLSFNKVTLPKLQLIAITSLLIAAKF 222
P+ R ++ W+ ++ +F L PET L+ +L+DR+L+ K L IAI+ +AAK
Sbjct: 42 PSQRDEVIQWLAKLKYQFNLYPETFALASSLLDRFLATVKAHPKYLSCIAISCFFLAAKT 101
Query: 223 --EEVNLPKLSNYSYITDNAYSNDEIKQAEFVILNKLEYNIGWPNPLNFL 270
E+ +P L + + S+ EI + E +IL+KL +++ PL+FL
Sbjct: 102 VEEDERIPVLKVLARDSFCGCSSSEILRMERIILDKLNWDLHTATPLDFL 151
>ECU09g1030 [D] KOG0653 Cyclin B and related kinase-activating proteins
Length = 216
Score = 60.1 bits (144), Expect = 6e-09
Identities = 40/135 (29%), Positives = 67/135 (49%), Gaps = 4/135 (2%)
Query: 138 LYTRQFETTPKINYLKDKNYEFYL-RPTMRSILVDWIIEVHCKFQLLPETLYLSINLMDR 196
L R F+ +N KN + + + + R LV W+ EV F T ++ ++DR
Sbjct: 9 LMKRVFQDITNVNR---KNIKLTIHKSSHRRKLVQWLYEVTDDFGYSQVTFSTAVFILDR 65
Query: 197 YLSFNKVTLPKLQLIAITSLLIAAKFEEVNLPKLSNYSYITDNAYSNDEIKQAEFVILNK 256
Y + L K QL+ I++L ++AK EE + +Y ++TD A S EI E +L
Sbjct: 66 YTEARGLDLEKYQLVGISALFLSAKIEEKWCKAVDDYVHVTDGACSGKEILDKEIEMLEV 125
Query: 257 LEYNIGWPNPLNFLR 271
++N+ P +FL+
Sbjct: 126 FDFNMMLRLPHSFLQ 140
>At5g65420 [D] KOG0656 G1/S-specific cyclin D
Length = 308
Score = 59.7 bits (143), Expect = 8e-09
Identities = 60/241 (24%), Positives = 118/241 (48%), Gaps = 26/241 (10%)
Query: 131 SDDIFDHLYTRQFETTPKINYLKD-KNYEFYLRPTMRSILVDWIIEVHCKFQLLPETLYL 189
S++I + ++ + P +Y+K ++ + L R L +WI + Q P L
Sbjct: 43 SEEIIMEMVEKEKQHLPSDDYIKRLRSGDLDLNVGRRDAL-NWIWKACEVHQFGPLCFCL 101
Query: 190 SINLMDRYLSFNKVTLPK---LQLIAITSLLIAAKFEEVNLPKLSNYSYITDN-AYSNDE 245
++N +DR+LS + + K LQL+A+ L +AAK EE +P L + +
Sbjct: 102 AMNYLDRFLSVHDLPSGKGWILQLLAVACLSLAAKIEETEVPMLIDLQVGDPQFVFEAKS 161
Query: 246 IKQAEFVILNKLEYNIGWPNPLN----FLRRISRCDEYDS---ITRTLGKCLIGYMISCP 298
+++ E ++LNKL++ + P + FLR++S+CD+ S I+R+L +I
Sbjct: 162 VQRMELLVLNKLKWRLRAITPCSYIRYFLRKMSKCDQEPSNTLISRSLQ--VIASTTKGI 219
Query: 299 HFIDVVPSKIASVAMFTA----QRIVHEDFQWDELWDYYSCFSFKDNEIELKELSQILIN 354
F++ PS++A+ + QR+ ++ + L FS E +K++ +++ +
Sbjct: 220 DFLEFRPSEVAAAVALSVSGELQRVHFDNSSFSPL------FSLLQKE-RVKKIGEMIES 272
Query: 355 D 355
D
Sbjct: 273 D 273
>Hs4502619 [D] KOG0656 G1/S-specific cyclin D
Length = 292
Score = 58.5 bits (140), Expect = 2e-08
Identities = 35/116 (30%), Positives = 65/116 (55%), Gaps = 4/116 (3%)
Query: 147 PKINYLKDKNYEFYLRPTMRSILVDWIIEVHCKFQLLPETLY-LSINLMDRYLSFNKVTL 205
P+ +Y + E ++P MR +L W++EV C+ Q E ++ L++N +DRYLS
Sbjct: 40 PRASYFQCVQRE--IKPHMRKMLAYWMLEV-CEEQRCEEEVFPLAMNYLDRYLSCVPTRK 96
Query: 206 PKLQLIAITSLLIAAKFEEVNLPKLSNYSYITDNAYSNDEIKQAEFVILNKLEYNI 261
+LQL+ +L+A+K E + TD+A S +++ E ++L KL++++
Sbjct: 97 AQLQLLGAVCMLLASKLRETTPLTIEKLCIYTDHAVSPRQLRDWEVLVLGKLKWDL 152
>At1g70210 [D] KOG0656 G1/S-specific cyclin D
Length = 339
Score = 57.4 bits (137), Expect = 4e-08
Identities = 35/116 (30%), Positives = 62/116 (53%), Gaps = 8/116 (6%)
Query: 161 LRPTMRSILVDWIIEVHCKFQLLPETLYLSINLMDRYLSFNKVTLPK-----LQLIAITS 215
L + R V WI++V + P T YL++N MDR+L + LP+ +QL+A+
Sbjct: 77 LDASAREDSVAWILKVQAYYNFQPLTAYLAVNYMDRFLYARR--LPETSGWPMQLLAVAC 134
Query: 216 LLIAAKFEEVNLPKLSNYSYI-TDNAYSNDEIKQAEFVILNKLEYNIGWPNPLNFL 270
L +AAK EE+ +P L ++ + IK+ E ++L+ L++ + P +F+
Sbjct: 135 LSLAAKMEEILVPSLFDFQVAGVKYLFEAKTIKRMELLVLSVLDWRLRSVTPFDFI 190
>YAL040c [D] KOG0653 Cyclin B and related kinase-activating proteins
Length = 580
Score = 55.8 bits (133), Expect = 1e-07
Identities = 35/135 (25%), Positives = 67/135 (48%), Gaps = 3/135 (2%)
Query: 129 DYSDDIFDHLYTRQFETTPKINYLKDKNYEFYLRPTMRSILVDWIIEVHCKFQLLPETLY 188
+Y++D DH + P N L + N + + P MR ++ D+I+ H + L TL+
Sbjct: 72 EYNNDQLDHYFRLSHTERPLYN-LTNFNSQPQVNPKMRFLIFDFIMYCHTRLNLSTSTLF 130
Query: 189 LSINLMDRYLSFNKVTLPKLQLIAITSLLIAAKF--EEVNLPKLSNYSYITDNAYSNDEI 246
L+ ++D+Y S + QL+++T+L I++KF + + L + N YS +
Sbjct: 131 LTFTILDKYSSRFIIKSYNYQLLSLTALWISSKFWDSKNRMATLKVLQNLCCNQYSIKQF 190
Query: 247 KQAEFVILNKLEYNI 261
E + L+++I
Sbjct: 191 TTMEMHLFKSLDWSI 205
>CE09256 [D] KOG0654 G2/Mitotic-specific cyclin A
Length = 130
Score = 55.8 bits (133), Expect = 1e-07
Identities = 28/76 (36%), Positives = 46/76 (59%)
Query: 165 MRSILVDWIIEVHCKFQLLPETLYLSINLMDRYLSFNKVTLPKLQLIAITSLLIAAKFEE 224
MR+IL+DW + ++ E ++L+++L+DR L + + QL+ ITS+ IA K+EE
Sbjct: 1 MRTILIDWFSDAVREYIFRNEAVHLAVSLVDRALPMFNINKMRFQLVGITSMRIAVKYEE 60
Query: 225 VNLPKLSNYSYITDNA 240
+ P LSN + D A
Sbjct: 61 IFPPILSNTRHSFDGA 76
>At5g67260 [D] KOG0656 G1/S-specific cyclin D
Length = 367
Score = 55.1 bits (131), Expect = 2e-07
Identities = 56/235 (23%), Positives = 111/235 (46%), Gaps = 20/235 (8%)
Query: 130 YSDDIFDHLYTRQFETTPKINYLKDKNYEFYLRPTMRSILVDWIIEVHCKFQLLPETLYL 189
+ DD L +++ ET P ++ + +L + R +DW++ V + T L
Sbjct: 64 WDDDEILSLISKENETNPCFG---EQILDGFL-VSCRKEALDWVLRVKSHYGFTSLTAIL 119
Query: 190 SINLMDRYLSFNKVTLPK---LQLIAITSLLIAAKFEEVNLPKLSNYSYITDN-AYSNDE 245
++N DR+++ K+ K QL+A+ SL +AAK EE+ +P L + +
Sbjct: 120 AVNYFDRFMTSIKLQTDKPWMSQLVAVASLSLAAKVEEIQVPLLLDLQVEEARYLFEAKT 179
Query: 246 IKQAEFVILNKLEYNIGWPNPLNFLRRI-----SRCDEYDSITRTLGKCLIGYMISCPHF 300
I++ E +IL+ L++ + P++F I S+ + R + LI +I+ F
Sbjct: 180 IQRMELLILSTLQWRMHPVTPISFFDHIIRRFGSKWHQQLDFCRKCERLLIS-VIADTRF 238
Query: 301 IDVVPSKIASVAMFTAQRIVHEDFQWDELWDYYSCFS--FKDNEIELKELSQILI 353
+ PS +A+ M +V E+ + + +Y S + K N+ ++ E ++L+
Sbjct: 239 MRYFPSVLATAIMI----LVFEELKPCDEVEYQSQITTLLKVNQEKVNECYELLL 289
>Hs4757936 [D] KOG0653 Cyclin B and related kinase-activating proteins
Length = 344
Score = 54.7 bits (130), Expect = 2e-07
Identities = 35/112 (31%), Positives = 58/112 (51%), Gaps = 2/112 (1%)
Query: 161 LRPTMRSILVDWIIEVHCKFQLLPETLYLSINLMDRYLSFNKVTLPKLQLIAITSLLIAA 220
L P +R+ V+ + + F ET L++N++DR+L+ KV L I + S L+AA
Sbjct: 51 LCPGLRNAKVEDLRSLANFFGSCTETFVLAVNILDRFLALMKVKPKHLSCIGVCSFLLAA 110
Query: 221 KF--EEVNLPKLSNYSYITDNAYSNDEIKQAEFVILNKLEYNIGWPNPLNFL 270
+ E+ N+P + I+ + +IK+ E +I KL Y + LNFL
Sbjct: 111 RIVEEDCNIPSTHDVIRISQCKCTASDIKRMEKIISEKLHYELEATTALNFL 162
>CE21610 [D] KOG0656 G1/S-specific cyclin D
Length = 405
Score = 54.7 bits (130), Expect = 2e-07
Identities = 33/128 (25%), Positives = 63/128 (48%)
Query: 142 QFETTPKINYLKDKNYEFYLRPTMRSILVDWIIEVHCKFQLLPETLYLSINLMDRYLSFN 201
++E + NY + + P R +DWI +V + + L+++L+DR++S
Sbjct: 81 EYEEALQPNYHYFTGVQENITPFHREQAIDWIYDVAKEENCDGDVFLLAVSLIDRFMSVQ 140
Query: 202 KVTLPKLQLIAITSLLIAAKFEEVNLPKLSNYSYITDNAYSNDEIKQAEFVILNKLEYNI 261
+ +Q+IA +L IA+K + + S +Y +DN+ D I Q E +I+ L++
Sbjct: 141 NILKHDIQMIAGVALFIASKLKAPHPMTASKIAYYSDNSCPIDMILQWELLIVTTLQWET 200
Query: 262 GWPNPLNF 269
P +F
Sbjct: 201 ESPTAFSF 208
>At5g10440 [D] KOG0656 G1/S-specific cyclin D
Length = 317
Score = 54.7 bits (130), Expect = 2e-07
Identities = 42/168 (25%), Positives = 88/168 (52%), Gaps = 14/168 (8%)
Query: 131 SDDIFDHLYTRQFETTPKINYLKD-KNYEFYLRPTMRSILVDWIIEVHCKFQLLPETLYL 189
S++I + ++ + +P+ +YLK +N + ++++ WI + + Q P + L
Sbjct: 35 SEEIVREMIEKERQHSPRDDYLKRLRNGDLDFNVRIQAL--GWIWKACEELQFGPLCICL 92
Query: 190 SINLMDRYLSFNKVTLPK---LQLIAITSLLIAAKFEEVNLPKLSNYSYITDN-AYSNDE 245
++N +DR+LS + + K +QL+A+ L +AAK EE N+P+L +
Sbjct: 93 AMNYLDRFLSVHDLPSGKAWTVQLLAVACLSLAAKIEETNVPELMQLQVGAPMFVFEAKS 152
Query: 246 IKQAEFVILNKLEYNIGWPNPLNFLRR-ISRCDEYDS------ITRTL 286
+++ E ++LN L + + P +++R +S+ + YD +TR+L
Sbjct: 153 VQRMELLVLNVLRWRLRAVTPCSYVRYFLSKINGYDQEPHSRLVTRSL 200
>At4g37630 [D] KOG0656 G1/S-specific cyclin D
Length = 321
Score = 54.3 bits (129), Expect = 3e-07
Identities = 37/117 (31%), Positives = 63/117 (53%), Gaps = 7/117 (5%)
Query: 166 RSILVDWIIEVHCKFQLLPETLYLSINLMDRYLSFNKVTLPK---LQLIAITSLLIAAKF 222
R I +DWI+ VH +P + L NL+ R +S K+ + ++L+++ L +AAK
Sbjct: 72 RLIAIDWILTVHKNKIWVPTSNSLHCNLILRSVSPQKIHRYETWAMRLLSVACLSLAAKM 131
Query: 223 EEVNLPKLSNYSYITDNAYSNDEIKQAEFVILNKLEYNIGWPNPLN----FLRRISR 275
EE +P LS Y D + D I++ E +IL+ L++ + P + FL +IS+
Sbjct: 132 EERIVPGLSQYPQDHDFVFKPDVIRKTELLILSTLDWKMNLITPFHYFNYFLAKISQ 188
>At4g34160 [D] KOG0656 G1/S-specific cyclin D
Length = 376
Score = 54.3 bits (129), Expect = 3e-07
Identities = 47/174 (27%), Positives = 85/174 (48%), Gaps = 11/174 (6%)
Query: 164 TMRSILVDWIIEVHCKFQLLPETLYLSINLMDRYLSFNKVTLPK---LQLIAITSLLIAA 220
T R V WI+ V+ + L+I +D+++ + K LQL+++ L +AA
Sbjct: 85 TDRKEAVGWILRVNAHYGFSTLAAVLAITYLDKFICSYSLQRDKPWMLQLVSVACLSLAA 144
Query: 221 KFEEVNLPKLSNYSY-ITDNAYSNDEIKQAEFVILNKLEYNIGWPNPLNFLRRISR--CD 277
K EE +P L ++ T + I++ E +IL+ LE+ + P++F+ I R
Sbjct: 145 KVEETQVPLLLDFQVEETKYVFEAKTIQRMELLILSTLEWKMHLITPISFVDHIIRRLGL 204
Query: 278 EYDSITRTLGKC--LIGYMISCPHFIDVVPSKIASVAMFTAQRIVHEDFQWDEL 329
+ ++ L KC L+ +IS F+ +PS +A+ M RI+ + +D L
Sbjct: 205 KNNAHWDFLNKCHRLLLSVISDSRFVGYLPSVVAAATM---MRIIEQVDPFDPL 255
>CE20913 [D] KOG0654 G2/Mitotic-specific cyclin A
Length = 123
Score = 53.5 bits (127), Expect = 5e-07
Identities = 28/76 (36%), Positives = 45/76 (58%)
Query: 165 MRSILVDWIIEVHCKFQLLPETLYLSINLMDRYLSFNKVTLPKLQLIAITSLLIAAKFEE 224
MR+IL+DW + ++ E ++L+ +L+DR L + + QL+ ITS+ IA K+EE
Sbjct: 1 MRTILIDWFSDAVREYISRKEAVHLAASLVDRALPMFNIDKMRFQLVGITSMRIAVKYEE 60
Query: 225 VNLPKLSNYSYITDNA 240
+ P LSN + D A
Sbjct: 61 IFPPILSNTRHSFDGA 76
>7292370 [D] KOG0654 G2/Mitotic-specific cyclin A
Length = 386
Score = 53.1 bits (126), Expect = 7e-07
Identities = 42/146 (28%), Positives = 70/146 (47%), Gaps = 14/146 (9%)
Query: 129 DYSDDIFDHLYTRQFETTPKINYLKDKNYEFYLRPTM--RSILVDWIIEVHCKFQLLPET 186
DY+ DIF + ++ P FYL P + R ++ + +L
Sbjct: 38 DYARDIFLTMREQELSRRPL----------FYLSPQLNERRRMLQLLKLATSAHKLSRCA 87
Query: 187 LYLSINLMDRYLSFNKVTLPKLQLIAITSLLIAAKFEEVN--LPKLSNYSYITDNAYSND 244
L+L++ MDR++ + K+ KL L+AIT L IAA+ E + +P+ S + + NAY+
Sbjct: 88 LHLAVYYMDRFVDYYKIRPDKLLLVAITCLHIAAQIENTDAFIPRYSEMNRLVKNAYTAF 147
Query: 245 EIKQAEFVILNKLEYNIGWPNPLNFL 270
E K E IL L + + P +F+
Sbjct: 148 EYKAVERKILCFLNFELIRPTTASFV 173
>Hs20541478 [D] KOG0653 Cyclin B and related kinase-activating proteins
Length = 153
Score = 52.8 bits (125), Expect = 9e-07
Identities = 37/98 (37%), Positives = 56/98 (56%), Gaps = 8/98 (8%)
Query: 129 DYSDDIFDHLYTRQFETTPKINYLKDKNYEFYLRPTMRSILVDWIIEVHCKFQLLPETLY 188
D SD F+ +YT+ E + +N ++K + + MR ILVDW+ ++ F++ ET
Sbjct: 44 DLSDPFFNSIYTK--EISSYMNLREEKQTD--INSVMRVILVDWLGKMQISFEMTQET-- 97
Query: 189 LSINLMDRYLSFNKVTLPK--LQLIAITSLLIAAKFEE 224
LS+ L Y F +V K LQL+ T+ L+AAKFEE
Sbjct: 98 LSLVLKPVYHYFMEVVCKKDGLQLLGPTAFLMAAKFEE 135
>At3g50070 [D] KOG0656 G1/S-specific cyclin D
Length = 361
Score = 52.4 bits (124), Expect = 1e-06
Identities = 42/161 (26%), Positives = 76/161 (47%), Gaps = 8/161 (4%)
Query: 166 RSILVDWIIEVHCKFQLLPETLYLSINLMDRYLSFNKVTLPK---LQLIAITSLLIAAKF 222
R +DWI +V + T L++N DR+++ K K QL A+ L +AAK
Sbjct: 86 REKALDWIFKVKSHYGFNSLTALLAVNYFDRFITSRKFQTDKPWMSQLTALACLSLAAKV 145
Query: 223 EEVNLPKLSNYSYITDN-AYSNDEIKQAEFVILNKLEYNIGWPNPLNFLRRISRCDEYDS 281
EE+ +P L ++ + I++ E ++L+ L++ + P++F I R + S
Sbjct: 146 EEIRVPFLLDFQVEEARYVFEAKTIQRMELLVLSTLDWRMHPVTPISFFDHIIRRYSFKS 205
Query: 282 ITRT--LGKC--LIGYMISCPHFIDVVPSKIASVAMFTAQR 318
+ L +C L+ +I F+ PS +A+ M + R
Sbjct: 206 HHQLEFLSRCESLLLSIIPDSRFLSFSPSVLATAIMVSVIR 246
>At2g22490 [D] KOG0656 G1/S-specific cyclin D
Length = 361
Score = 52.0 bits (123), Expect = 2e-06
Identities = 49/192 (25%), Positives = 91/192 (46%), Gaps = 15/192 (7%)
Query: 131 SDDIFDHLYTRQFETTPKINYLKDKNYEFYLRPTMRSILVDWIIEVHCKFQLLPETLYLS 190
S+D + R+ E P +Y+K + L ++R+ +DWI++V + + LS
Sbjct: 63 SEDRIKEMLVREIEFCPGTDYVK-RLLSGDLDLSVRNQALDWILKVCAHYHFGHLCICLS 121
Query: 191 INLMDRYLSFNKVTLPK-----LQLIAITSLLIAAKFEEVNLPKLSNYSYITDN-AYSND 244
+N +DR+L+ LPK QL+A++ L +A+K EE ++P + + +
Sbjct: 122 MNYLDRFLT--SYELPKDKDWAAQLLAVSCLSLASKMEETDVPHIVDLQVEDPKFVFEAK 179
Query: 245 EIKQAEFVILNKLEYNIGWPNPLNFL----RRISRCDEYDSITRTLGKCLIGYMISCPHF 300
IK+ E +++ L + + P +F+ +IS + I R+ I F
Sbjct: 180 TIKRMELLVVTTLNWRLQALTPFSFIDYFVDKISGHVSENLIYRS--SRFILNTTKAIEF 237
Query: 301 IDVVPSKIASVA 312
+D PS+IA+ A
Sbjct: 238 LDFRPSEIAAAA 249
>At5g02110 [D] KOG0656 G1/S-specific cyclin D
Length = 341
Score = 50.4 bits (119), Expect = 5e-06
Identities = 39/151 (25%), Positives = 67/151 (43%), Gaps = 7/151 (4%)
Query: 118 SQDKEDVTMCYDYSDDIFDHLYTRQFETTPKINYLKDKNYEFYLRPTM---RSILVDWII 174
S D + V M + + E N DK EF++ + R W+I
Sbjct: 27 SHDNDVVKMYPEIDAATMEEAIAMDLEKELCFNNHGDKFVEFFVSKKLTDYRFHAFQWLI 86
Query: 175 EVHCKFQLLPETLYLSINLMDRYLSF---NKVTLPKLQLIAITSLLIAAKFEEVNLPKLS 231
+ + L ET++ + N DR++ ++ T ++L+A+TSL IA+KF EV P L
Sbjct: 87 QTRSRLNLSYETVFSAANCFDRFVYMTCCDEWTNWMVELVAVTSLSIASKFNEVTTPLLE 146
Query: 232 NYSYI-TDNAYSNDEIKQAEFVILNKLEYNI 261
+ + + + Q E +IL LE+ +
Sbjct: 147 ELEMEGLTHMFHVNTVAQMELIILKALEWRV 177
Database: KOG eukaryal database 04/03
Posted date: Apr 14, 2003 1:07 PM
Number of letters in database: 30,389,216
Number of sequences in database: 60,738
Lambda K H
0.318 0.134 0.399
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 23,783,632
Number of Sequences: 60738
Number of extensions: 1001599
Number of successful extensions: 4159
Number of sequences better than 1.0e-05: 78
Number of HSP's better than 0.0 without gapping: 63
Number of HSP's successfully gapped in prelim test: 15
Number of HSP's that attempted gapping in prelim test: 4044
Number of HSP's gapped (non-prelim): 81
length of query: 408
length of database: 30,389,216
effective HSP length: 109
effective length of query: 299
effective length of database: 23,768,774
effective search space: 7106863426
effective search space used: 7106863426
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)