ORF STATUS Function Best COG Functional category Pathways and functional systems
r_klactIV3946 good O KOG1339 Posttranslational modification, protein turnover, chaperones Aspartyl protease
Only best alignment is shown:
BLASTP 2.2.3 [May-13-2002]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= r_klactIV3946 1338262 1336730 -511
(511 letters)
Database: KOG eukaryal database 04/03
60,738 sequences; 30,389,216 total letters
Searching..................................................done
Color Key for Alignment Scores: 
Score E
Sequences producing significant alignments: (bits) Value
YIL015w [O] KOG1339 Aspartyl protease 318 9e-87
YLR121c [O] KOG1339 Aspartyl protease 263 4e-70
YLR120c [O] KOG1339 Aspartyl protease 253 6e-67
YDR144c [O] KOG1339 Aspartyl protease 244 2e-64
YIR039c [O] KOG1339 Aspartyl protease 184 3e-46
Hs4505757 [O] KOG1339 Aspartyl protease 110 7e-24
7297765 [O] KOG1339 Aspartyl protease 105 2e-22
Hs4503145 [O] KOG1339 Aspartyl protease 101 2e-21
7304149 [O] KOG1339 Aspartyl protease 100 9e-21
YPL154c [O] KOG1339 Aspartyl protease 96 1e-19
CE03567 [O] KOG1339 Aspartyl protease 94 6e-19
7297766 [O] KOG1339 Aspartyl protease 93 1e-18
7297427 [O] KOG1339 Aspartyl protease 92 1e-18
SPAC26A3.01 [O] KOG1339 Aspartyl protease 89 2e-17
7303185 [O] KOG1339 Aspartyl protease 87 6e-17
7290034 [O] KOG1339 Aspartyl protease 87 6e-17
CE04971 [O] KOG1339 Aspartyl protease 86 1e-16
Hs4506475 [O] KOG1339 Aspartyl protease 85 2e-16
CE21681 [O] KOG1339 Aspartyl protease 85 3e-16
Hs22063875 [O] KOG1339 Aspartyl protease 84 4e-16
Hs22063872 [O] KOG1339 Aspartyl protease 84 4e-16
CE09540 [O] KOG1339 Aspartyl protease 84 5e-16
7300254 [O] KOG1339 Aspartyl protease 84 7e-16
Hs4758754 [O] KOG1339 Aspartyl protease 82 1e-15
Hs4503143 [O] KOG1339 Aspartyl protease 82 2e-15
7300255 [O] KOG1339 Aspartyl protease 81 3e-15
7296074 [O] KOG1339 Aspartyl protease 81 4e-15
CE09542 [O] KOG1339 Aspartyl protease 80 6e-15
CE16843 [O] KOG1339 Aspartyl protease 80 7e-15
CE21685 [O] KOG1339 Aspartyl protease 78 3e-14
7296075 [O] KOG1339 Aspartyl protease 77 6e-14
At1g69100 [O] KOG1339 Aspartyl protease 77 8e-14
CE11478 [O] KOG1339 Aspartyl protease 76 1e-13
7296076 [O] KOG1339 Aspartyl protease 75 2e-13
CE09539 [O] KOG1339 Aspartyl protease 75 2e-13
7300253 [O] KOG1339 Aspartyl protease 75 2e-13
YDR349c [O] KOG1339 Aspartyl protease 74 4e-13
At1g65240 [O] KOG1339 Aspartyl protease 72 2e-12
SPCC1795.09 [O] KOG1339 Aspartyl protease 72 2e-12
CE11480 [O] KOG1339 Aspartyl protease 71 4e-12
7296077 [O] KOG1339 Aspartyl protease 70 8e-12
At4g04460 [O] KOG1339 Aspartyl protease 70 1e-11
Hs22063919 [O] KOG1339 Aspartyl protease 68 4e-11
At1g11910 [O] KOG1339 Aspartyl protease 67 5e-11
CE21683 [O] KOG1339 Aspartyl protease 67 6e-11
CE20430 [O] KOG1339 Aspartyl protease 67 8e-11
At1g62290 [O] KOG1339 Aspartyl protease 63 9e-10
CE21684 [O] KOG1339 Aspartyl protease 63 1e-09
At5g36260 [O] KOG1339 Aspartyl protease 63 1e-09
CE09738 [O] KOG1339 Aspartyl protease 59 2e-08
Hs19923395 [O] KOG1339 Aspartyl protease 59 2e-08
At1g05840 [O] KOG1339 Aspartyl protease 54 6e-07
At1g09750 [O] KOG1339 Aspartyl protease 54 7e-07
Hs21040362 [O] KOG1339 Aspartyl protease 53 1e-06
At3g50050 [O] KOG1339 Aspartyl protease 53 1e-06
Hs21040360 [O] KOG1339 Aspartyl protease 52 2e-06
CE09541 [O] KOG1339 Aspartyl protease 51 4e-06
At2g36670 [O] KOG1339 Aspartyl protease 51 4e-06
>YIL015w [O] KOG1339 Aspartyl protease
Length = 587
Score = 318 bits (816), Expect = 9e-87
Identities = 156/376 (41%), Positives = 241/376 (63%), Gaps = 9/376 (2%)
Query: 56 QDYFYTVELGVGTPSQKINCIFDTGSSDLWVPAKSNPFCLGNKLDTNGTNE-FHGTEITP 114
++ +Y L +GTPSQ + +FDTGS+D WV SNPFCL N ++ +N ++G E+ P
Sbjct: 41 EEMYYATTLDIGTPSQSLTVLFDTGSADFWVMDSSNPFCLPNSNTSSYSNATYNGEEVKP 100
Query: 115 ILDCDKIGVFDP--GSSYSLSATGYNFSTQYFDGSYSDGFWVVDDISIADQQVPDLQFAV 172
+DC + ++ S+Y G F Y DG+++DG W + +SI +P++QF V
Sbjct: 101 SIDCRSMSTYNEHRSSTYQYLENG-RFYITYADGTFADGSWGTETVSINGIDIPNIQFGV 159
Query: 173 ANISSAP-SGVLGVGLPRLEAVRGYDGAPNANYDNFPQTLKSNRLINRVLYSLYFDSGDL 231
A ++ P SGVLG+G PR E+V+GY+GAPN Y NFPQ LKS ++I+ V YSL+ +S D
Sbjct: 160 AKYATTPVSGVLGIGFPRRESVKGYEGAPNEYYPNFPQILKSEKIIDVVAYSLFLNSPDS 219
Query: 232 ESGTVLFGGIDEKKYDGVLYTLPLVNIYEQI-DEPAAFDITLQGLGIRSESNCKDTVIAH 290
+G+++FG IDE K+ G L+T P+VN Y I D PA +T+QGLG +++S+C+
Sbjct: 220 GTGSIVFGAIDESKFSGDLFTFPMVNEYPTIVDAPATLAMTIQGLGAQNKSSCEHETFTT 279
Query: 291 KKAPALLDSGSTIMGAPQEALESIAQELGAAFSESDGLYVLDCPASNDDRTFYFDFGELK 350
K P LLDSG++++ AP+ + +A + A++SE +G+Y+LDCP S D + FDFG+L+
Sbjct: 280 TKYPVLLDSGTSLLNAPKVIADKMASFVNASYSEEEGIYILDCPVSVGDVEYNFDFGDLQ 339
Query: 351 LKVPIHDLLYLPESGQNYCGLAIIASGEEWILGDLVLKSAYVVYDLDNLEISIAQVKTTS 410
+ VP+ L+ PE+ +YCG A+ + + +LGD+ L SAYVV+DLDN +IS+AQ +
Sbjct: 340 ISVPLSSLILSPETEGSYCGFAVQPTNDSMVLGDVFLSSAYVVFDLDNYKISLAQANWNA 399
Query: 411 ---GSRIQTVSATGSL 423
++ + GS+
Sbjct: 400 SEVSKKLVNIQTDGSI 415
>YLR121c [O] KOG1339 Aspartyl protease
Length = 508
Score = 263 bits (673), Expect = 4e-70
Identities = 157/411 (38%), Positives = 231/411 (56%), Gaps = 40/411 (9%)
Query: 26 DSKVIQLQLLKPADRS---LQKRSKSFES-KLNPQDYFYTVELGVGTPSQKINCIFDTGS 81
D K +++ K + L KRS E L + FY+VEL +GTPSQ + + DTGS
Sbjct: 25 DGKYVKIPFTKKKNGDNGELSKRSNGHEKFVLANEQSFYSVELAIGTPSQNLTVLLDTGS 84
Query: 82 SDLWVPAKSNPFCLGNKLDTNGTNEFHGTEITPILDCDKIGVFDPGSSYSLSATGYN-FS 140
+DLWVP K NP+C ++DCD+ GVFD S + A + F
Sbjct: 85 ADLWVPGKGNPYC------------------GSVMDCDQYGVFDKTKSSTFKANKSSPFY 126
Query: 141 TQYFDGSYSDGFWVVDDISIADQQVPDLQFAVANISSAPSGVLGVGLPRLEAVRGYDGAP 200
Y DG+Y++G + D + + + L FAVAN S++ GVLG+GL LE Y G
Sbjct: 127 AAYGDGTYAEGAFGQDKLKYNELDLSGLSFAVANESNSTFGVLGIGLSTLEVT--YSGKV 184
Query: 201 ------NANYDNFPQTLKSNRLINRVLYSLYFDSGDLESGTVLFGGIDEKKYDGVLYTLP 254
+ YDNFP LK + I+ YSL+ + SG++LFG +D KY+G LYT+P
Sbjct: 185 AIMDKRSYEYDNFPLFLKHSGAIDATAYSLFLNDESQSSGSILFGAVDHSKYEGQLYTIP 244
Query: 255 LVNIYEQ--IDEPAAFDITLQGLGIRSESNCKDTVIAHKKAPALLDSGSTIMGAPQEALE 312
LVN+Y+ P AFD+TLQGLG++++ ++ + K PALLDSG+T+ P +A+
Sbjct: 245 LVNLYKSQGYQHPVAFDVTLQGLGLQTDK--RNITLTTTKLPALLDSGTTLTYLPSQAVA 302
Query: 313 SIAQELGAAFSESDGLYVLDCPASNDDRTFYFDFGELKLKVPIHDLLYLPESGQNYCGLA 372
+A+ L A++S++ G Y CP+S++ + FDFG ++ P+ D + ++ C LA
Sbjct: 303 LLAKSLNASYSKTLGYYEYTCPSSDNKTSVAFDFGGFRINAPLSD--FTMQTSVGTCVLA 360
Query: 373 II--ASGEEWILGDLVLKSAYVVYDLDNLEISIAQVKTTSG-SRIQTVSAT 420
II A ILGD L++AYVVYDLDN EIS+AQ K +G ++ + +T
Sbjct: 361 IIPQAGNATAILGDSFLRNAYVVYDLDNYEISLAQAKYGTGKENVEVIKST 411
>YLR120c [O] KOG1339 Aspartyl protease
Length = 569
Score = 253 bits (645), Expect = 6e-67
Identities = 162/448 (36%), Positives = 224/448 (49%), Gaps = 61/448 (13%)
Query: 36 KPADRSLQKRSKSFESKLNPQDYFYTVELGVGTPSQKINCIFDTGSSDLWVPAKSNPFCL 95
KP R L++ E + Q FY+V+L VGTP Q + + DTGSSDLW+ NP+C
Sbjct: 59 KPEVRLLKRADGYEEIIITNQQSFYSVDLEVGTPPQNVTVLVDTGSSDLWIMGSDNPYCS 118
Query: 96 GNKLDT-------------------NGTNEFH-----GTEITPI---------------- 115
N + + N N F G+ I P
Sbjct: 119 SNSMGSSRRRVIDKRDDSSSGGSLINDINPFGWLTGTGSAIGPTATGLGGGSGTATQSVP 178
Query: 116 -----LDCDKIGVFDPGSSYSLSATGYNFSTQYFDGSYSDGFWVVDDISIADQQVPDLQF 170
+DC + G F S + + FS Y DG+++ G + D + ++D V L F
Sbjct: 179 ASEATMDCQQYGTFSTSGSSTFRSNNTYFSISYGDGTFASGTFGTDVLDLSDLNVTGLSF 238
Query: 171 AVANISSAPSGVLGVGLPRLEAVRGYDGAPNAN----YDNFPQTLKSNRLINRVLYSLYF 226
AVAN +++ GVLG+GLP LE A ++ YDNFP LK++ I YSLY
Sbjct: 239 AVANETNSTMGVLGIGLPELEVTYSGSTASHSGKAYKYDNFPIVLKNSGAIKSNTYSLYL 298
Query: 227 DSGDLESGTVLFGGIDEKKYDGVLYTLPLVNIYEQ--IDEPAAFDITLQGLGIRSESNCK 284
+ D GT+LFG +D KY G LYT+P+VN P FD+T+ G+GI S+S
Sbjct: 299 NDSDAMHGTILFGAVDHSKYTGTLYTIPIVNTLSASGFSSPIQFDVTINGIGI-SDSGSS 357
Query: 285 DTVIAHKKAPALLDSGSTIMGAPQEALESIAQELGAAFSESDGLYVLDCPASNDDRTFYF 344
+ + K PALLDSG+T+ PQ + IA ELGA +S G YVLDCP S+D F
Sbjct: 358 NKTLTTTKIPALLDSGTTLTYLPQTVVSMIATELGAQYSSRIGYYVLDCP-SDDSMEIVF 416
Query: 345 DFGELKLKVPIHDLLYLPESGQNYCGLAIIASGEE--WILGDLVLKSAYVVYDLDNLEIS 402
DFG + P+ + S C L II + ++ ILGD L +AYVVYDL+NLEIS
Sbjct: 417 DFGGFHINAPLSSFIL---STGTTCLLGIIPTSDDTGTILGDSFLTNAYVVYDLENLEIS 473
Query: 403 IAQVK-TTSGSRIQTVSATGSLPQTRKS 429
+AQ + T+ I+ + T S+P K+
Sbjct: 474 MAQARYNTTSENIEII--TSSVPSAVKA 499
>YDR144c [O] KOG1339 Aspartyl protease
Length = 596
Score = 244 bits (623), Expect = 2e-64
Identities = 150/425 (35%), Positives = 221/425 (51%), Gaps = 49/425 (11%)
Query: 42 LQKRSKSFES-KLNPQDYFYTVELGVGTPSQKINCIFDTGSSDLWVPAKSNPFCLGNKLD 100
L R +E +L Q+ FY+VEL +GTP QK+ + DTGSSDLWV NP+C K D
Sbjct: 62 LMTRDDDYELVELTNQNSFYSVELDIGTPPQKVTVLVDTGSSDLWVTGSDNPYCSTKKKD 121
Query: 101 TNGTN-------------EFHGTEI---------------------TPILDCDKIGVFDP 126
T G++ E TEI + ++DC G F+
Sbjct: 122 TTGSSFKQVNKDALASVVESVFTEISYDTTIVTSEATATFDSTASTSQLIDCATYGTFNT 181
Query: 127 GSSYSLSATGYNFSTQYFDGSYSDGFWVVDDISIADQQVPDLQFAVANISSAPSGVLGVG 186
S + ++ FS Y D +++ G W D +S+ D + L FAVAN +++ GVLG+G
Sbjct: 182 SKSSTFNSNNTEFSIAYGDTTFASGTWGHDQLSLNDLNITGLSFAVANETNSTVGVLGIG 241
Query: 187 LPRLEAVRGYDGA------PNANYDNFPQTLKSNRLINRVLYSLYFDSGDLESGTVLFGG 240
LP LE+ Y G + Y+NFP LK++ +I YSL+ + D + GT+LFG
Sbjct: 242 LPGLEST--YSGVSLSSVQKSYTYNNFPMVLKNSGVIKSTAYSLFANDSDSKHGTILFGA 299
Query: 241 IDEKKYDGVLYTLPLVNIYEQ--IDEPAAFDITLQGLGI-RSESNCKDTVIAHKKAPALL 297
+D KY G LYT+P++N + +P F +TLQGLG + + T + K P LL
Sbjct: 300 VDHGKYAGDLYTIPIINTLQHRGYKDPIQFQVTLQGLGTSKGDKEDNLTTLTTTKIPVLL 359
Query: 298 DSGSTIMGAPQEALESIAQELGAAFSESDGLYVLDC-PASNDDRTFYFDFGELKLKVPIH 356
DSG+TI P E ++ +A ++GA +S + G Y++DC ++ + FDFG L +
Sbjct: 360 DSGTTISYMPTELVKMLADQVGATYSSAYGYYIMDCIKEMEEESSIIFDFGGFYLSNWLS 419
Query: 357 DLLYLPESGQNYCGLAIIASGEEW-ILGDLVLKSAYVVYDLDNLEISIAQVK-TTSGSRI 414
D + +S N C L I + ILGD L + YVVYDLDN+EIS+AQ + G I
Sbjct: 420 DFQLVTDSRSNICILGIAPQSDPTIILGDNFLANTYVVYDLDNMEISMAQANFSDDGEYI 479
Query: 415 QTVSA 419
+ + +
Sbjct: 480 EIIES 484
>YIR039c [O] KOG1339 Aspartyl protease
Length = 537
Score = 184 bits (467), Expect = 3e-46
Identities = 125/382 (32%), Positives = 185/382 (47%), Gaps = 26/382 (6%)
Query: 60 YTVELGVGTPSQKINCIFDTGSSDLWVPAKSNPFC--LGNKLDTNGTNE------FHGTE 111
Y V++ +GTP Q + DTGSSD+ V +C + + D T+ F+G
Sbjct: 67 YVVKMEIGTPPQTLYLQLDTGSSDMIVNNADIAYCKSMSDGSDYASTDNYELTATFNGLP 126
Query: 112 ITPILD------CDKIGVFDPGSSYSLSATGYNFSTQYFDGSYSDGFWVVDDISIADQQV 165
T I C G FD +S + F+ Y DG+Y G + D +S + +
Sbjct: 127 STTISSEAYNTLCSYWGTFDASNSSTFENNATFFNNTYGDGTYYAGTYGTDVVSFENITL 186
Query: 166 PDLQFAVANISSA-PSGVLGVGLPRLEAVRGYDGAPNAN-----YDNFPQTLKSNRLINR 219
D F V+N + PSG+LG+ LP E G + A N YDNFP LK+ IN+
Sbjct: 187 NDFTFGVSNDTIGNPSGILGISLPIAEFTDGIEYALALNRTPFIYDNFPMELKNQGKINK 246
Query: 220 VLYSLYFDSGDLESGTVLFGGIDEKKYDGVLYTLPLVNIYEQIDEPAAFDITLQGLGIRS 279
+ YSL+ + D G++LFG +D+ KY G LYTLP++ + + IT Q + I
Sbjct: 247 IAYSLFLNGPDAHFGSILFGAVDKSKYTGQLYTLPMLQAFNTLGSNPGMIITAQSVAI-L 305
Query: 280 ESNCKDTVIAHKKAPALLDSGSTIMGAPQEALESIAQELGAAFSESDGLYVLDCPASNDD 339
+S + ++ + P +LDSG+T P E E+I + +S D Y+ DC N D
Sbjct: 306 DSESGNKTVSDIQFPVMLDSGTTFSYLPTEIAEAIGKSFDGEYSSDDQGYIFDCSKVN-D 364
Query: 340 RTFYFDFGELKLKVPIHDLLYLPESGQNYCGLAIIASGEEWILGDLVLKSAYVVYDLDNL 399
DFG + I + + S ++ C L + S ++LGD L AYVVYDL+N
Sbjct: 365 TLLSVDFGGFNISANISNFV---TSAKDRCVLNVKQSESTYMLGDAFLVDAYVVYDLENY 421
Query: 400 EISIAQVKTTSGSR-IQTVSAT 420
EISIAQ + I+ +S T
Sbjct: 422 EISIAQASFNNQEEDIEVISDT 443
>Hs4505757 [O] KOG1339 Aspartyl protease
Length = 388
Score = 110 bits (274), Expect = 7e-24
Identities = 98/364 (26%), Positives = 160/364 (43%), Gaps = 64/364 (17%)
Query: 57 DYFYTVELGVGTPSQKINCIFDTGSSDLWVPAKSNPFCLGNKLDTNGTNEFHGTEITPIL 116
D Y E+ +GTP Q +FDTGSS+LWVP + +C
Sbjct: 70 DAAYFGEISIGTPPQNFLVLFDTGSSNLWVP---SVYCQSQA------------------ 108
Query: 117 DCDKIGVFDPGSSYSLSATGYNFSTQYFDGSYSDGFWVVDDISIADQQVPDLQFAVAN-- 174
C F+P S + S G FS QY GS + GF+ D +++ QVP+ +F ++
Sbjct: 109 -CTSHSRFNPSESSTYSTNGQTFSLQYGSGSLT-GFFGYDTLTVQSIQVPNQEFGLSENE 166
Query: 175 -----ISSAPSGVLGVGLPRLEAVRGYDGAPNANYDNFPQTLKSNRLINRVLYSLYFDSG 229
+ + G++G+ P L D A A Q + + ++S+Y +
Sbjct: 167 PGTNFVYAQFDGIMGLAYPALSV----DEATTA-----MQGMVQEGALTSPVFSVYLSNQ 217
Query: 230 DLES-GTVLFGGIDEKKYDGVLYTLPLV-NIYEQIDEPAAFDITLQGLGIRSESNCKDTV 287
S G V+FGG+D Y G +Y P+ +Y QI F I Q G SE
Sbjct: 218 QGSSGGAVVFGGVDSSLYTGQIYWAPVTQELYWQIG-IEEFLIGGQASGWCSEG------ 270
Query: 288 IAHKKAPALLDSGSTIMGAPQEALESIAQELGAAFSESDGLYVLDCPASNDDRTFYFDFG 347
A++D+G++++ PQ+ + ++ Q GA E G ++++C + + + F
Sbjct: 271 -----CQAIVDTGTSLLTVPQQYMSALLQATGAQEDEY-GQFLVNCNSIQNLPSLTFIIN 324
Query: 348 ELKLKVPIHDLLYLPESGQNYCGLAI------IASGEE-WILGDLVLKSAYVVYDLDNLE 400
++ +P + S YC + + +G+ WILGD+ L+S Y VYDL N
Sbjct: 325 GVEFPLPPSSYIL---SNNGYCTVGVEPTYLSSQNGQPLWILGDVFLRSYYSVYDLGNNR 381
Query: 401 ISIA 404
+ A
Sbjct: 382 VGFA 385
>7297765 [O] KOG1339 Aspartyl protease
Length = 423
Score = 105 bits (261), Expect = 2e-22
Identities = 97/372 (26%), Positives = 150/372 (40%), Gaps = 59/372 (15%)
Query: 60 YTVELGVGTPSQKINCIFDTGSSDLWVPAKSNPFCLGNKLDTNGTNEFHGTEITPILDCD 119
YT+ L +GTP Q N FDTGSSDLWVP+ + + TNE C
Sbjct: 74 YTIRLCIGTPPQCFNLQFDTGSSDLWVPS----------VKCSSTNE----------ACQ 113
Query: 120 KIGVFDPGSSYSLSATGYNFSTQYFDGSYSDGFWVVDDISIADQQVPDLQFA-------V 172
K ++ +S S G FS QY GS S GF D + I + + FA
Sbjct: 114 KHNKYNSSASSSHVEDGKGFSIQYGSGSLS-GFLSTDTVDIDGMVIRNQTFAEAIDEPGS 172
Query: 173 ANISSAPSGVLGVGLPRLEAVRGYDGAPNANYDNFPQTLKSNRLINRVLYSLYF--DSGD 230
A +++ G++G+ A G +DN + L+ ++S+Y D
Sbjct: 173 AFVNTIFDGIIGM------AFASISGGVTTPFDN----IIRQGLVKHPVFSVYLRRDGTS 222
Query: 231 LESGTVLFGGIDEKKYDGVLYTLPLVNIYEQIDEPAAFDITLQGLGIRSESNCKDTVIAH 290
G V++GGID Y G + +P + PA + T + I C
Sbjct: 223 QSGGEVIWGGIDRSIYRGCINYVP-------VSMPAYWQFTANSVKIEGILLCNG----- 270
Query: 291 KKAPALLDSGSTIMGAPQEALESIAQELGAAFSESDGLYVLDCPASNDDRTFYFDFGELK 350
A+ D+G++++ P A ++I + L A DG +DC + + G
Sbjct: 271 --CQAIADTGTSLIAVPLRAYKAINKVLNAT-DAGDGEAFVDCSSLCRLPNVNLNIGGTT 327
Query: 351 LKVPIHDLLYLPESGQN----YCGLAIIASGEEWILGDLVLKSAYVVYDLDNLEISIAQV 406
+ D +Y ++ N G + WILGD+ L Y V+D+ I A++
Sbjct: 328 YTLTPKDYIYKVQADNNQTLCLSGFTYLQGNLLWILGDIFLGKVYTVFDVGKERIGFAKL 387
Query: 407 KTTSGSRIQTVS 418
K S R+ S
Sbjct: 388 KKHSSYRVYASS 399
>Hs4503145 [O] KOG1339 Aspartyl protease
Length = 396
Score = 101 bits (252), Expect = 2e-21
Identities = 101/374 (27%), Positives = 160/374 (42%), Gaps = 68/374 (18%)
Query: 50 ESKLNPQDYFYTVELGVGTPSQKINCIFDTGSSDLWVPAKSNPFCLGNKLDTNGTNEFHG 109
E +N D Y + +G+P Q IFDTGSS+LWVP + +C T+
Sbjct: 68 EPLINYLDMEYFGTISIGSPPQNFTVIFDTGSSNLWVP---SVYCTSPACKTHSR----- 119
Query: 110 TEITPILDCDKIGVFDPGSSYSLSATGYNFSTQYFDGSYSDGFWVVDDISIADQQVPDLQ 169
F P S + S G +FS QY GS S G D +S+ V Q
Sbjct: 120 --------------FQPSQSSTYSQPGQSFSIQYGTGSLS-GIIGADQVSVEGLTVVGQQ 164
Query: 170 FAVA-------NISSAPSGVLGVGLPRLEAVRGYDGAPNANYDNFPQTLKSNRLINRVLY 222
F + + + G+LG+G P L G +DN + + L++ ++
Sbjct: 165 FGESVTEPGQTFVDAEFDGILGLGYPSLAV-----GGVTPVFDN----MMAQNLVDLPMF 215
Query: 223 SLYFDSGDLESGT---VLFGGIDEKKYDGVLYTLPLV-NIYEQIDEPAAFDITLQGLGIR 278
S+Y S E G ++FGG D + G L +P+ Y QI A +I + G +
Sbjct: 216 SVYMSSNP-EGGAGSELIFGGYDHSHFSGSLNWVPVTKQAYWQI---ALDNIQVGGTVMF 271
Query: 279 SESNCKDTVIAHKKAPALLDSGSTIMGAPQEALESIAQELGAAFSESDGLYVLDCPASN- 337
C+ A++D+G++++ P + ++ + +GAA DG Y ++C N
Sbjct: 272 CSEGCQ----------AIVDTGTSLITGPSDKIKQLQNAIGAA--PVDGEYAVECANLNV 319
Query: 338 -DDRTFYFDFGELKLKVPIHDLLYLPESGQNYC-----GLAI-IASGEEWILGDLVLKSA 390
D TF + L + LL + G +C GL I +G WILGD+ ++
Sbjct: 320 MPDVTFTINGVPYTLSPTAYTLLDFVD-GMQFCSSGFQGLDIHPPAGPLWILGDVFIRQF 378
Query: 391 YVVYDLDNLEISIA 404
Y V+D N + +A
Sbjct: 379 YSVFDRGNNRVGLA 392
>7304149 [O] KOG1339 Aspartyl protease
Length = 392
Score = 99.8 bits (247), Expect = 9e-21
Identities = 99/370 (26%), Positives = 149/370 (39%), Gaps = 60/370 (16%)
Query: 54 NPQDYFYTVELGVGTPSQKINCIFDTGSSDLWVPAKSNPFCLGNKLDTNGTNEFHGTEIT 113
N D Y + +G+P Q +FDTGSS+LWVP+K + H T I
Sbjct: 67 NYMDAQYYGPIAIGSPPQNFRVVFDTGSSNLWVPSK----------------KCHLTNIA 110
Query: 114 PILDCDKIGVFDPGSSYSLSATGYNFSTQYFDGSYSDGFWVVDDISIADQQVPDLQFAVA 173
C +D S + + G F+ QY GS S G+ D +SIA + D FA A
Sbjct: 111 ----CLMHNKYDASKSKTYTKNGTEFAIQYGSGSLS-GYLSTDTVSIAGLDIKDQTFAEA 165
Query: 174 -------NISSAPSGVLGVGLPRLEAVRGYDGAPNANYDNFPQTLKSNRLINRVLYSLYF 226
+++ G+LG+G + D Y + Q LI+ ++S Y
Sbjct: 166 LSEPGLVFVAAKFDGILGLGYNSISV----DKVKPPFYAMYEQ-----GLISAPVFSFYL 216
Query: 227 --DSGDLESGTVLFGGIDEKKYDGVLYTLPLVNIYEQIDEPAAFDITLQGLGIRSESNCK 284
D E G ++FGG D Y G LP + A + I + I CK
Sbjct: 217 NRDPASPEGGEIIFGGSDPNHYTGEFTYLP-------VTRKAYWQIKMDAASIGDLQLCK 269
Query: 285 DTVIAHKKAPALLDSGSTIMGAPQEALESIAQELGAAFSESDGLYVLDCPASNDDRTFYF 344
+ D+G++++ AP E SI Q++G G YV+ C F
Sbjct: 270 G------GCQVIADTGTSLIAAPLEEATSINQKIGGT-PIIGGQYVVSCDLIPQLPVIKF 322
Query: 345 DFGELKLKVPIHD-LLYLPESGQNYC-----GLAI-IASGEEWILGDLVLKSAYVVYDLD 397
G ++ D +L + + G+ C GL I +G WILGD+ + Y +D+
Sbjct: 323 VLGGKTFELEGKDYILRVAQMGKTICLSGFMGLDIPPPNGPLWILGDVFIGKYYTEFDMG 382
Query: 398 NLEISIAQVK 407
N + A K
Sbjct: 383 NDRVGFADAK 392
>YPL154c [O] KOG1339 Aspartyl protease
Length = 405
Score = 96.3 bits (238), Expect = 1e-19
Identities = 102/362 (28%), Positives = 151/362 (41%), Gaps = 65/362 (17%)
Query: 60 YTVELGVGTPSQKINCIFDTGSSDLWVPAKSNPFCLGNKLDTNGTNEFHGTEITPILDCD 119
Y ++ +GTP Q I DTGSS+LWVP +NE L C
Sbjct: 91 YYTDITLGTPPQNFKVILDTGSSNLWVP----------------SNECGS------LACF 128
Query: 120 KIGVFDPGSSYSLSATGYNFSTQYFDGSYSDGFWVVDDISIADQQVPDLQFAVANISSAP 179
+D +S S A G F+ QY GS +G+ D +SI D +P FA A +S P
Sbjct: 129 LHSKYDHEASSSYKANGTEFAIQYGTGSL-EGYISQDTLSIGDLTIPKQDFAEA--TSEP 185
Query: 180 ---------SGVLGVGLPRLEAVRGYDGAPNANYDNFPQTLKSNRLINRVLYSLYFDSGD 230
G+LG+G + D Y+ Q L + R + L S D
Sbjct: 186 GLTFAFGKFDGILGLGYDTISV----DKVVPPFYNAIQQDLLDEK---RFAFYLGDTSKD 238
Query: 231 LES-GTVLFGGIDEKKYDGVLYTLPLVNIYEQIDEPAAFDITLQGLGIRSESNCKDTVIA 289
E+ G FGGIDE K+ G + LP + A +++ +G+G+ D
Sbjct: 239 TENGGEATFGGIDESKFKGDITWLP-------VRRKAYWEVKFEGIGL------GDEYAE 285
Query: 290 HKKAPALLDSGSTIMGAPQEALESIAQELGAAFSESDGLYVLDCPASNDDRTFYFDFGEL 349
+ A +D+G++++ P E I E+GA + G Y LDC ++ F+F
Sbjct: 286 LESHGAAIDTGTSLITLPSGLAEMINAEIGAKKGWT-GQYTLDCNTRDNLPDLIFNFNGY 344
Query: 350 KLKVPIHDLLYLPESGQNYCGLAIIAS------GEEWILGDLVLKSAYVVYDLDNLEISI 403
+ +D L SG C AI G I+GD L+ Y +YDL N + +
Sbjct: 345 NFTIGPYDYT-LEVSGS--CISAITPMDFPEPVGPLAIVGDAFLRKYYSIYDLGNNAVGL 401
Query: 404 AQ 405
A+
Sbjct: 402 AK 403
>CE03567 [O] KOG1339 Aspartyl protease
Length = 444
Score = 93.6 bits (231), Expect = 6e-19
Identities = 98/375 (26%), Positives = 151/375 (40%), Gaps = 62/375 (16%)
Query: 54 NPQDYFYTVELGVGTPSQKINCIFDTGSSDLWVPAKSNPFCLGNKLDTNGTNEFHGTEIT 113
N D Y + +GTP+Q IFDTGSS+LW+P+K PF
Sbjct: 88 NYMDAQYFGTISIGTPAQNFTVIFDTGSSNLWIPSKKCPFY------------------- 128
Query: 114 PILDCDKIGVFDPGSSYSLSATGYNFSTQYFDGSYSDGFWVVDDISIADQQVPDLQFAVA 173
+ C +D SS + G + QY GS GF D + +A D FA A
Sbjct: 129 -DIACMLHHRYDSKSSSTYKEDGRKMAIQYGTGSMK-GFISKDSVCVAGVCAEDQPFAEA 186
Query: 174 N-------ISSAPSGVLGVGLPRLEAVRGYDGAPNANYDNFPQTLKSNRLINRVLYSLYF 226
+++ G+LG+ P + AV G N TL + + L+S +
Sbjct: 187 TSEPGITFVAAKFDGILGMAYPEI-AVLGVQPVFN--------TLFEQKKVPSNLFSFWL 237
Query: 227 DSG-DLE-SGTVLFGGIDEKKYDGVLYTLPLVNI-YEQIDEPAAFDITLQGLGIRSESNC 283
+ D E G + FGGID ++Y + +P+ Y Q G G+ SN
Sbjct: 238 NRNPDSEIGGEITFGGIDSRRYVEPITYVPVTRKGYWQFKMDKVV-----GSGVLGCSN- 291
Query: 284 KDTVIAHKKAPALLDSGSTIMGAPQEALESIAQELGAAFSESDGLYVLDCPASNDDRTFY 343
A+ D+G++++ P+ +E+I +GA G Y++ C
Sbjct: 292 --------GCQAIADTGTSLIAGPKAQIEAIQNFIGAE-PLIKGEYMISCDKVPTLPPVS 342
Query: 344 FDFGELKLKVPIHD-LLYLPESGQNYCGLAIIAS------GEEWILGDLVLKSAYVVYDL 396
F G + + D +L + + G+ C + GE WILGD+ + Y V+D
Sbjct: 343 FVIGGQEFSLKGEDYVLKVSQGGKTICLSGFMGIDLPERVGELWILGDVFIGRYYSVFDF 402
Query: 397 DNLEISIAQVKTTSG 411
D + AQ KT G
Sbjct: 403 DQNRVGFAQAKTADG 417
>7297766 [O] KOG1339 Aspartyl protease
Length = 391
Score = 92.8 bits (229), Expect = 1e-18
Identities = 93/373 (24%), Positives = 155/373 (40%), Gaps = 58/373 (15%)
Query: 46 SKSFESKLNPQDYFYTVELGVGTPSQKINCIFDTGSSDLWVPAKSNPFCLGNKLDTNGTN 105
S + E+ N + Y + +GTP Q+ N +FDTGS++LWVP+ S P
Sbjct: 62 SGATENLHNSMNNEYYGVIAIGTPEQRFNILFDTGSANLWVPSASCP------------- 108
Query: 106 EFHGTEITPILDCDKIGVFDPGSSYSLSATGYNFSTQYFDGSYSDGFWVVDDISIADQQV 165
C + +D +S + A G F+ +Y GS S GF D ++IA +
Sbjct: 109 -------ASNTACQRHNKYDSSASSTYVANGEEFAIEYGTGSLS-GFLSNDIVTIAGISI 160
Query: 166 PDLQFAVA------NISSAP-SGVLGVGLPRLEAVRGYDGAPNANYDNFPQTLKSNRLIN 218
+ F A AP +G+LG+ + AV G +DN + S L++
Sbjct: 161 QNQTFGEALSEPGTTFVDAPFAGILGLAFSAI-AVDGV----TPPFDN----MISQGLLD 211
Query: 219 RVLYSLYF--DSGDLESGTVLFGGIDEKKYDGVLYTLPLVNIYEQIDEPAAFDITLQGLG 276
+ S Y + G ++ GGID Y G L +P + PA + + +
Sbjct: 212 EPVISFYLKRQGTAVRGGELILGGIDSSLYRGSLTYVP-------VSVPAYWQFKVNTIK 264
Query: 277 IRSESNCKDTVIAHKKAPALLDSGSTIMGAPQEALESIAQELGAAFSESDGLYVLDCPAS 336
C A+ D+G++++ P A I ++LGA +++DG + C
Sbjct: 265 TNGTLLCNG-------CQAIADTGTSLIAVPLAAYRKINRQLGA--TDNDGEAFVRCGRV 315
Query: 337 NDDRTFYFDFGELKLKVPIHD-LLYLPESGQNYC--GLAIIASGEEWILGDLVLKSAYVV 393
+ + G + D ++ + ++GQ YC + WILGD+ + Y V
Sbjct: 316 SSLPKVNLNIGGTVFTLAPRDYIVKVTQNGQTYCMSAFTYMEGLSFWILGDVFIGKFYTV 375
Query: 394 YDLDNLEISIAQV 406
+D N I A+V
Sbjct: 376 FDKGNERIGFARV 388
>7297427 [O] KOG1339 Aspartyl protease
Length = 372
Score = 92.4 bits (228), Expect = 1e-18
Identities = 94/369 (25%), Positives = 147/369 (39%), Gaps = 58/369 (15%)
Query: 45 RSKSFESKLNPQDYFYTVELGVGTPSQKINCIFDTGSSDLWVPAKSNPFCLGNKLDTNGT 104
RS E N + Y + +GTP+Q +FD+GSS+LWVP+ + C + T+
Sbjct: 54 RSVDEEQLSNSMNMAYYGAISIGTPAQSFKVLFDSGSSNLWVPSNT---CKSDACLTHNQ 110
Query: 105 NEFHGTEITPILDCDKIGVFDPGSSYSLSATGYNFSTQYFDGSYSDGFWVVDDISIADQQ 164
+D +S + A G +FS QY GS + G+ D + +
Sbjct: 111 -------------------YDSSASSTYVANGESFSIQYGTGSLT-GYLSTDTVDVNGLS 150
Query: 165 VPDLQFAVA------NISSAP-SGVLGVGLPRLEAVRGYDGAPNANYDNFPQTLKSNRLI 217
+ FA + N + A G+LG+ L DG Y+ Q L N +
Sbjct: 151 IQSQTFAESTNEPGTNFNDANFDGILGMAYESL----AVDGVAPPFYNMVSQGLVDNSVF 206
Query: 218 NRVLYSLYFDSGDLESGTVLFGGIDEKKYDGVLYTLPLVNIYEQIDEPAAFDITLQGLGI 277
+ + L D G ++FGG D Y G L +P I E + T+ G I
Sbjct: 207 S---FYLARDGTSTMGGELIFGGSDASLYSGALTYVP-------ISEQGYWQFTMAGSSI 256
Query: 278 RSESNCKDTVIAHKKAPALLDSGSTIMGAPQEALESIAQELGAAFSESDGLYVLDCPASN 337
S C D A+ D+G++++ AP A ++++ L DG LDC + +
Sbjct: 257 DGYSLCDD-------CQAIADTGTSLIVAPYNAYITLSEILNVG---EDG--YLDCSSVS 304
Query: 338 DDRTFYFDFGELKLKVPIHDLLYLPESGQNYCGLAIIASGEEWILGDLVLKSAYVVYDLD 397
F+ G + Y+ +S N + WILGD+ + Y +DL
Sbjct: 305 SLPDVTFNIGGTNF--VLKPSAYIIQSDGNCMSAFEYMGTDFWILGDVFIGQYYTEFDLG 362
Query: 398 NLEISIAQV 406
N I A V
Sbjct: 363 NNRIGFAPV 371
>SPAC26A3.01 [O] KOG1339 Aspartyl protease
Length = 514
Score = 88.6 bits (218), Expect = 2e-17
Identities = 102/432 (23%), Positives = 183/432 (41%), Gaps = 41/432 (9%)
Query: 60 YTVELGVGTPSQKINCIFDTGSSDLWVPAKSNPFCLGNKL--DTNGTNEFHGTEITPILD 117
Y L +G+ + + DTGS WV AK+ +++ DT+G + T
Sbjct: 76 YFANLTLGSNERVYSLTLDTGSPYTWVTAKNITALSASEIWSDTDGVDAGRSTSDIRTNA 135
Query: 118 CDKIGVFDPGSSYSLSATGYNFSTQYFDGSYSD-----GFWVVDDISIADQQVPDLQFAV 172
C FD S+ +A N ST F SY D G+ +VD+ A +P +F +
Sbjct: 136 CTNYTCFDYSST---TARRTNSSTIGFLASYGDNTTVLGYNMVDNAYFAGLTLPGFEFGL 192
Query: 173 AN-------ISSAPSGVLGVGLPR-LEAVRGYDGAPNANYDNFPQTLKSNRLINRVLYSL 224
A IS P G++G+ + + + D L S +I+ + +
Sbjct: 193 ATREYDSSQISVTP-GIIGLSVAMTITGISSDDKVVAFTPPTIVDQLVSANVIDTPAFGI 251
Query: 225 YFDSGDLESGTVLFGGIDEKKYDGVLYTLPLVNIYEQIDEPAAFDITLQGLGIRSESNCK 284
Y + + G ++FGG D+ K +G ++ VNI D+ + + L+ + + + ++
Sbjct: 252 YLNE---DVGELIFGGYDKAKINGSVHW---VNISSS-DDSTFYSVNLESITVTNSTSSN 304
Query: 285 DTVIAHKKAPAL-------LDSGSTIMGAPQEALESIAQELGAAFSESDGLYVLDCPASN 337
+ + + + + LD+G+ + P++ +ESIA + SE G V+ C + +
Sbjct: 305 NVQSSKRSSKDIEVNTTVTLDTGTVYIYLPEDTVESIADQYQGIVSEY-GYVVIYCDSFS 363
Query: 338 DDRTFYFDFG-ELKLKVPIHDL-LYLPES-GQNYCGLAII-ASGEEWILGDLVLKSAYVV 393
D F+FG + V ++DL +Y ES + C LA+ ++LG L+ Y +
Sbjct: 364 DSDYISFNFGSDADFHVSVNDLVIYRQESTSGDICYLALFEGDTSSYLLGQYFLQYVYSI 423
Query: 394 YDLDNLEISIAQVKT--TSGSRIQTVSATGSLPQTRKSNXXXXXXXXXXXXXXXXVFDKP 451
YD D +I +A + + TS + Q ++ +L ++ S F
Sbjct: 424 YDWDAQKIGLAALNSNATSTANHQILNINSAL-RSVTSGQSVSATPTVSMSIAATSFGSS 482
Query: 452 LPKKCQKSPSKT 463
L SPS T
Sbjct: 483 LVLTASASPSST 494
>7303185 [O] KOG1339 Aspartyl protease
Length = 404
Score = 87.0 bits (214), Expect = 6e-17
Identities = 85/371 (22%), Positives = 144/371 (37%), Gaps = 61/371 (16%)
Query: 54 NPQDYFYTVELGVGTPSQKINCIFDTGSSDLWVPAKSNPFCLGNKLDTNGTNEFHGTEIT 113
N D Y + +GTP Q IFDTGSS+LWVP+ + C + N + T
Sbjct: 79 NYLDAQYFGPITIGTPPQTFKVIFDTGSSNLWVPSAT---CASTMVACRVHNRYFAKRST 135
Query: 114 PILDCDKIGVFDPGSSYSLSATGYNFSTQYFDGSYSDGFWVVDDISIADQQVPDLQFAVA 173
S G +F+ Y GS S GF D + +A ++ D FA A
Sbjct: 136 -----------------SHQVRGDHFAIHYGSGSLS-GFLSTDTVRVAGLEIRDQTFAEA 177
Query: 174 NISSAPSGVLGVGLPRLEAVRGYDGAPNANYDNFPQ--------TLKSNRLINRVLYSLY 225
P + +DG Y + + L+ + ++S+Y
Sbjct: 178 TEMPGP----------IFLAAKFDGIFGLAYRSISMQRIKPPFYAMMEQGLLTKPIFSVY 227
Query: 226 FD-SGDLESGTVLFGGIDEKKYDGVLYTLPLVNIYEQIDEPAAFDITLQGLGIRSESNCK 284
+G+ + G + FGG + Y G Y Q+ A + + + IR+ C+
Sbjct: 228 LSRNGEKDGGAIFFGGSNPHYYTGNF-------TYVQVSHRAYWQVKMDSAVIRNLELCQ 280
Query: 285 DTVIAHKKAPALLDSGSTIMGAPQEALESIAQELGAAFSESDGLYVLDCPASNDDRTFYF 344
+ ++D+G++ + P + I + +G S S G +++ C + D F
Sbjct: 281 ------QGCEVIIDTGTSFLALPYDQAILINESIGGTPS-SFGQFLVPCDSVPDLPKITF 333
Query: 345 DFGELKLKVPIHDLLYLP-ESGQNYCGLAIIA------SGEEWILGDLVLKSAYVVYDLD 397
G + + H+ ++ + C A IA SG WILGD+ L Y +D++
Sbjct: 334 TLGGRRFFLESHEYVFRDIYQDRRICSSAFIAVDLPSPSGPLWILGDVFLGKYYTEFDME 393
Query: 398 NLEISIAQVKT 408
I A ++
Sbjct: 394 RHRIGFADARS 404
>7290034 [O] KOG1339 Aspartyl protease
Length = 407
Score = 87.0 bits (214), Expect = 6e-17
Identities = 96/371 (25%), Positives = 151/371 (39%), Gaps = 66/371 (17%)
Query: 54 NPQDYFYTVELGVGTPSQKINCIFDTGSSDLWVPAKSNPFCLGNKLDTNGTNEFHGTEIT 113
N ++ Y + +GTP Q FDTGSS+LWVP S C+
Sbjct: 71 NYDNFQYYGNISIGTPGQDFLVQFDTGSSNLWVPGSS---CISTA--------------- 112
Query: 114 PILDCDKIGVFDPGSSYSLSATGYNFSTQYFDGSYSDGFWVVDDISIADQQVPDLQFAVA 173
C VF S + A G FS Y GS S G+ VD + A + F
Sbjct: 113 ----CQDHQVFYKNKSSTYVANGTAFSITYGTGSVS-GYLSVDCVGFAGLTIQSQTFGEV 167
Query: 174 NISSAPS-------GVLGVGLPRLEAVRGYDGAPNANYDNFPQTLKSNRLINRVLYSLYF 226
+ G+LG+G P L AV G P Q + L+ ++S +
Sbjct: 168 TTEQGTNFVDAYFDGILGMGFPSL-AVDGV--TPTF------QNMMQQGLVQSPVFSFFL 218
Query: 227 -DSGDLE--SGTVLFGGIDEKKYDGVLYTLPLVNIYEQIDEPAAFDITLQGLGIRSESNC 283
D+G + G ++ GG D Y G L Y + + A + + + S S
Sbjct: 219 RDNGSVTFYGGELILGGSDPSLYSGSL-------TYVNVVQAAYWKFQTDYIKVGSTS-- 269
Query: 284 KDTVIAHKKAPALLDSGSTIMGAPQEALESIAQELGAAFSESDGLYVLDCPASNDDRTFY 343
A A+ D+G++++ APQ + I+Q A S+GL+ +C +S
Sbjct: 270 -----ISTFAQAIADTGTSLIIAPQAQYDQISQLFNA---NSEGLF--EC-SSTSYPDLI 318
Query: 344 FDFGELKLKVPIHDLLYLPESGQNYCGLAIIASGEE-WILGDLVLKSAYVVYDLDNLEIS 402
+ + K+P Y+ E +++C LAI + ++ WI+GD+ L Y +D+ N +
Sbjct: 319 ININGVDFKIPAK--YYIIEE-EDFCSLAIQSINQDFWIMGDVFLGRIYTEFDVGNQRLG 375
Query: 403 IAQVKTTSGSR 413
A V + G R
Sbjct: 376 FAPVNSAVGLR 386
>CE04971 [O] KOG1339 Aspartyl protease
Length = 709
Score = 86.3 bits (212), Expect = 1e-16
Identities = 96/419 (22%), Positives = 166/419 (38%), Gaps = 64/419 (15%)
Query: 19 RQIEFDHDSKVIQLQLLKPA-DRSLQKRSKSFESKLNPQDYFYTVELGVGTPSQKINCIF 77
R +++ D ++ + + K + D S+ + +E D Y + +GTP Q+ I
Sbjct: 318 RWVQYRKDREIRRFMMNKQSNDMSVGQYVNDYE------DEAYVGNITIGTPQQQFKVIL 371
Query: 78 DTGSSDLWVP----------AKSNPFCLGNKLDTNGTNE-FHGTEITPILDCDKIGVFDP 126
DTGSS+LW+P + P C G ++ G C FD
Sbjct: 372 DTGSSNLWIPDITCGTKPENCSTVPACRGIICQFECDDQACCGAGANYTDSCFYQNKFDA 431
Query: 127 GSSYSLSATGYNFSTQYFDGSYSDGFWVVDDIS---IADQQ--VPDLQFAVANISSA--- 178
S S G NF +Y GS + GF D I+ I + Q VP+ F A +A
Sbjct: 432 SKSSSYKTNGRNFIIEYGTGS-ARGFLGQDTITFGGIGEPQLAVPNTVFGQATSLAAFFE 490
Query: 179 ---PSGVLGVGLPRLEAVRGYDGAPNANYDNFPQTLKSNRLINRVLYSLYF----DSGDL 231
G+LG+ + + NA N L++ L++++ D +
Sbjct: 491 GQPLDGILGLAFKSIAVDQITPPFINAINQN---------LVDLPLFTVFLEHEGDQNGV 541
Query: 232 ESGTVLFGGIDEKKYDGVLYTLPLVNIYEQIDEPAAFDITLQGLGIRSESNCKDTVIAHK 291
+ G +GGID K V+ Y+ + + + +G S + K +
Sbjct: 542 QGGVYTYGGIDTKNCGPVI-------AYQPLSSATYYQFKMSAIGSGSYHSSKGWQV--- 591
Query: 292 KAPALLDSGSTIMGAPQEALESIAQELGAAFSESDGLYVLDCPASNDDRTFYFDFGELKL 351
+ D+G++++G P+ + +IA +GA + + G+Y+L C A + T G
Sbjct: 592 ----ISDTGTSLIGGPKAYVSAIADAVGATWRDDYGVYILPCSAKIN--TLDITIGNQVY 645
Query: 352 KVPIHDLLYLPESGQNYCGLAII-----ASGEEWILGDLVLKSAYVVYDLDNLEISIAQ 405
+ + + G N C AI G WILGD ++ +YD+ + A+
Sbjct: 646 NIDSSNTIIPLGDGSNNCIYAIFPFSSGGFGPSWILGDPFIRQYCNIYDVGTQRVGFAK 704
>Hs4506475 [O] KOG1339 Aspartyl protease
Length = 406
Score = 85.1 bits (209), Expect = 2e-16
Identities = 91/368 (24%), Positives = 154/368 (41%), Gaps = 61/368 (16%)
Query: 54 NPQDYFYTVELGVGTPSQKINCIFDTGSSDLWVPAKSNPFCLGNKLDTNGTNEFHGTEIT 113
N D Y E+G+GTP Q +FDTGSS++WVP+ C ++L T
Sbjct: 80 NYMDTQYYGEIGIGTPPQTFKVVFDTGSSNVWVPSSK---C--SRLYT------------ 122
Query: 114 PILDCDKIGVFDPGSSYSLSATGYNFSTQYFDGSYSDGFWVVDDISIADQQVPDLQFAVA 173
C +FD S S G + +Y G+ S GF D I++ V + V
Sbjct: 123 ---ACVYHKLFDASDSSSYKHNGTELTLRYSTGTVS-GFLSQDIITVGGITVTQMFGEVT 178
Query: 174 NISSAP------SGVLGVGLPRLEAVRGYDGAPNANYDNFPQTLKSNRLINRVLYSLYF- 226
+ + P GV+G+G + G +DN + S ++ ++S Y+
Sbjct: 179 EMPALPFMLAEFDGVVGMGF-----IEQAIGRVTPIFDN----IISQGVLKEDVFSFYYN 229
Query: 227 -DSGDLES--GTVLFGGIDEKKYDGVLYTLPLVNIYEQIDEPAAFDITLQGLGIRSESNC 283
DS + +S G ++ GG D + Y+G + + L+ + + I ++G+ + S
Sbjct: 230 RDSENSQSLGGQIVLGGSDPQHYEGNFHYINLI-------KTGVWQIQMKGVSVGS---- 278
Query: 284 KDTVIAHKKAPALLDSGSTIMGAPQEALESIAQELGAAFSESDGLYVLDCPASNDDRTFY 343
T++ AL+D+G++ + ++E + + LGA D YV+ C
Sbjct: 279 -STLLCEDGCLALVDTGASYISGSTSSIEKLMEALGAKKRLFD--YVVKCNEGPTLPDIS 335
Query: 344 FDFGELKLKVPIHDLLYLPE-SGQNYCGLAIIA------SGEEWILGDLVLKSAYVVYDL 396
F G + + D ++ S + C LAI A +G W LG ++ Y +D
Sbjct: 336 FHLGGKEYTLTSADYVFQESYSSKKLCTLAIHAMDIPPPTGPTWALGATFIRKFYTEFDR 395
Query: 397 DNLEISIA 404
N I A
Sbjct: 396 RNNRIGFA 403
>CE21681 [O] KOG1339 Aspartyl protease
Length = 396
Score = 84.7 bits (208), Expect = 3e-16
Identities = 92/379 (24%), Positives = 150/379 (39%), Gaps = 57/379 (15%)
Query: 43 QKRSKSFESKLNPQDYFYTVELGVGTPSQKINCIFDTGSSDLWVPAKSNPFCLGNKLDTN 102
Q+ + F+ ++ D FY + +GTP Q + DTGSS+LWV + T
Sbjct: 51 QQLNTGFQPFVDYFDDFYLGNITLGTPPQPATVVLDTGSSNLWV--------IDAACKTQ 102
Query: 103 GTNEFHGTEITPILDCDKIGVFDPGSSYSLSATGYNFSTQYFDGSYSDGFWVVDDISIAD 162
N + + T FD S + FS QY GS +G+ D ++
Sbjct: 103 ACNGYPDSGYTK-------QKFDTTKSTTFVKETRKFSIQYGSGS-CNGYLGKDVLNFGG 154
Query: 163 QQVPDLQFAVANISS------APSGVLGVGLPRLEAVRGYDGAPNANYDNFPQTLKSNRL 216
V +F V+ + G+LG+G P L + N L + +
Sbjct: 155 LTVQSQEFGVSTHLADVFGYQPVDGILGLGWPALAVDQVVPPMQN---------LIAQKQ 205
Query: 217 INRVLYSLYFDSG-----DLESGTVLFGGIDEKKYDGVLYTLPL-VNIYEQIDEPAAFDI 270
++ L++++ D G + +G ID + +PL Y Q F +
Sbjct: 206 LDAPLFTVWLDRNLQIAQGTPGGLITYGAIDTVNCAKQVTYVPLSAKTYWQ------FPL 259
Query: 271 TLQGLGIRSESNCKDTVIAHKKAPALLDSGSTIMGAPQEALESIAQELGAAFSESDGLYV 330
+G SE+ KD VI+ D+G++ +GAP + +I ++ A F S LY
Sbjct: 260 DAFAVGTYSETK-KDQVIS--------DTGTSWLGAPNTIVSAIVKQTKAVFDWSTELYT 310
Query: 331 LDCPASNDDRTFYFDFGELKLKVPIHDLLYLPESGQNYCGLAIIASGE-----EWILGDL 385
+DC F G + V + + + G C LA+ + G WILGD
Sbjct: 311 VDCSTMKTQPDLIFTIGGAQFPVKSVEYVLDLQLGGGKCALAVFSMGSGGFGPSWILGDT 370
Query: 386 VLKSAYVVYDLDNLEISIA 404
++ VYD+ N +I A
Sbjct: 371 FIRQYCNVYDIGNGQIGFA 389
>Hs22063875 [O] KOG1339 Aspartyl protease
Length = 325
Score = 84.3 bits (207), Expect = 4e-16
Identities = 78/304 (25%), Positives = 134/304 (43%), Gaps = 35/304 (11%)
Query: 114 PILDCDKIGVFDPGSSYSLSATGYNFSTQYFDGSYSDGFWVVDDISIADQQVPDLQFAVA 173
P+L F+P S + +T S Y GS + G D + + + F ++
Sbjct: 45 PVLPAANHNRFNPEDSSTYQSTSETVSITYGTGSMT-GILGYDTVQVGGISDTNQIFGLS 103
Query: 174 NISS------AP-SGVLGVGLPRLEAVRGYDGAPNANYDNFPQTLKSNRLINRVLYSLYF 226
AP G+LG+ P + + GA +DN + + L+++ L+S+Y
Sbjct: 104 ETEPGSFLYYAPFDGILGLAYPSISS----SGATPV-FDN----IWNQGLVSQDLFSVYL 154
Query: 227 DSGDLESGTVLFGGIDEKKYDGVLYTLPL-VNIYEQIDEPAAFDITLQGLGIRSESNCKD 285
+ D V+FGGID Y G L +P+ V Y QI IT+ G I C+
Sbjct: 155 SADDQSGSVVIFGGIDSSYYTGSLNWVPVTVEGYWQI---TVDSITMNGEAIACAEGCQ- 210
Query: 286 TVIAHKKAPALLDSGSTIMGAPQEALESIAQELGAAFSESDGLYVLDCPASNDDRTFYFD 345
A++D+G++++ P + +I ++GA+ SDG V+ C A + F
Sbjct: 211 ---------AIVDTGTSLLTGPTSPIANIQSDIGAS-ENSDGDMVVSCSAISSLPDIVFT 260
Query: 346 FGELKLKVPIHDLLYLPESG--QNYCGLAI-IASGEEWILGDLVLKSAYVVYDLDNLEIS 402
++ VP + E + G+ + SGE WILGD+ ++ + V+D N ++
Sbjct: 261 INGVQYPVPPSAYILQSEGSCISGFQGMNLPTESGELWILGDVFIRQYFTVFDRANNQVG 320
Query: 403 IAQV 406
+A V
Sbjct: 321 LAPV 324
>Hs22063872 [O] KOG1339 Aspartyl protease
Length = 325
Score = 84.3 bits (207), Expect = 4e-16
Identities = 78/304 (25%), Positives = 134/304 (43%), Gaps = 35/304 (11%)
Query: 114 PILDCDKIGVFDPGSSYSLSATGYNFSTQYFDGSYSDGFWVVDDISIADQQVPDLQFAVA 173
P+L F+P S + +T S Y GS + G D + + + F ++
Sbjct: 45 PVLPAANHNRFNPEDSSTYQSTSETVSITYGTGSMT-GILGYDTVQVGGISDTNQIFGLS 103
Query: 174 NISS------AP-SGVLGVGLPRLEAVRGYDGAPNANYDNFPQTLKSNRLINRVLYSLYF 226
AP G+LG+ P + + GA +DN + + L+++ L+S+Y
Sbjct: 104 ETEPGSFLYYAPFDGILGLAYPSISS----SGATPV-FDN----IWNQGLVSQDLFSVYL 154
Query: 227 DSGDLESGTVLFGGIDEKKYDGVLYTLPL-VNIYEQIDEPAAFDITLQGLGIRSESNCKD 285
+ D V+FGGID Y G L +P+ V Y QI IT+ G I C+
Sbjct: 155 SADDQSGSVVIFGGIDSSYYTGSLNWVPVTVEGYWQI---TVDSITMNGEAIACAEGCQ- 210
Query: 286 TVIAHKKAPALLDSGSTIMGAPQEALESIAQELGAAFSESDGLYVLDCPASNDDRTFYFD 345
A++D+G++++ P + +I ++GA+ SDG V+ C A + F
Sbjct: 211 ---------AIVDTGTSLLTGPTSPIANIQSDIGAS-ENSDGDMVVSCSAISSLPDIVFT 260
Query: 346 FGELKLKVPIHDLLYLPESG--QNYCGLAI-IASGEEWILGDLVLKSAYVVYDLDNLEIS 402
++ VP + E + G+ + SGE WILGD+ ++ + V+D N ++
Sbjct: 261 INGVQYPVPPSAYILQSEGSCISGFQGMNLPTESGELWILGDVFIRQYFTVFDRANNQVG 320
Query: 403 IAQV 406
+A V
Sbjct: 321 LAPV 324
>CE09540 [O] KOG1339 Aspartyl protease
Length = 395
Score = 84.0 bits (206), Expect = 5e-16
Identities = 91/375 (24%), Positives = 152/375 (40%), Gaps = 82/375 (21%)
Query: 57 DYFYTVELGVGTPSQKINCIFDTGSSDLWVPAKSNPFCLGNKLDTNGTNEFHGTEITPIL 116
D Y + +GTP Q+ + DTGS++LWVP + +GT
Sbjct: 70 DVEYLGNITIGTPPQQFIVVLDTGSANLWVPGSN----------CDGT------------ 107
Query: 117 DCDKIGVFDPGSSYSLSATGYNFSTQYFDGSYSDGFWVVDDISI---ADQQ--VPDLQFA 171
C FD S + G ++ QY GS + G VD ++ ++QQ VP F
Sbjct: 108 -CKGKSEFDSSKSTTFKKNGQSWQIQYESGS-AKGIMGVDTVAFGGASEQQLLVPSTTFG 165
Query: 172 VAN-ISS-----APSGVLGVGLPRLEAVRGYDGAPNANYDNFPQTLKSNRLINRVLYSLY 225
+A+ ISS A G+LG+ L AV G P N N +++++ L++++
Sbjct: 166 IASHISSNFKNDAAEGILGLAFTSL-AVDGVT-PPLINAIN-------KKILDQPLFTVF 216
Query: 226 FD----SGDLESGTVLFGGIDEKKYDGVLYTLPLVNIYEQIDEPAAFDITLQGLGIRSES 281
+ + ++ G +G +D V+ Y+ + + G + S S
Sbjct: 217 LEHKGTAKNVGGGVFTYGAVDTTNCGPVI-------AYQPLSSATYYQFVADGFKLGSYS 269
Query: 282 NCKDTVIAHKKAPALLDSGSTIMGAPQEALESIAQELGAAFSESDGLYVLDCPASNDDRT 341
N +KK+ + D+GS+++G P + AQ LGA + D Y L C S
Sbjct: 270 N-------NKKSQVISDTGSSLIGGPSAVINGFAQALGAKYHSDDDAYYLPCSTSK---- 318
Query: 342 FYFDFGELKLKV-----PIHDLLYLPESGQ-NYCGLAIIA-----SGEEWILGDLVLKSA 390
G L + + I + Y+ + G + C A + G WI GD ++
Sbjct: 319 -----GTLDITIGGNVYSIEPVNYILDVGMGDTCVFAAFSFDFGGFGPSWIFGDPFIRQY 373
Query: 391 YVVYDLDNLEISIAQ 405
+YD+ I A+
Sbjct: 374 CNIYDIGQQRIGFAK 388
>7300254 [O] KOG1339 Aspartyl protease
Length = 309
Score = 83.6 bits (205), Expect = 7e-16
Identities = 86/367 (23%), Positives = 153/367 (41%), Gaps = 75/367 (20%)
Query: 57 DYFYTVELGVGTPSQKINCIFDTGSSDLWVPAKSNPFCLGNKLDTNGTNEFHGTEITPIL 116
+Y+ T+ +G P Q IFDTGSS+ W+P+ + P + N
Sbjct: 2 EYYGTIAMG--NPRQNFTVIFDTGSSNTWLPSVNCP--MSNSA----------------- 40
Query: 117 DCDKIGVFDPGSSYSLSATGYNFSTQYFDGSYSDGFWVVDDISIADQQVPDLQFA----- 171
C ++ S S G NF+ +Y G G+ D + IA ++P F
Sbjct: 41 -CQNHRKYNSSRSSSYIPDGRNFTLRYGSGMVV-GYLSKDTMHIAGAELPHFTFGESLFL 98
Query: 172 --VANISSAPSGVLGVGLPRLEAVRGYDGAPNANYDNFPQTLKSNRLINRVLYSLYFDSG 229
A S G++G+GL L +N F + L + RL+ + ++S+Y
Sbjct: 99 QHFAFSSVKFDGLVGLGLGVLSW---------SNTTPFLELLCAQRLLEKCVFSVYLRRD 149
Query: 230 DLESGTVLFGGIDEKKYDGVLYTLPLVNIYEQIDEPAAFDITLQGLGIRSESNCKDTVIA 289
E ++FGG DE K++G L+ +P+ + + I+ +G +
Sbjct: 150 PRE---IVFGGFDESKFEGKLHYVPVSQWHTW-----SLQISKSSVGTKQIGG------- 194
Query: 290 HKKAPALLDSGSTIMGAPQEALESIAQELGAAFSESDGLYVLDCPASN--------DDRT 341
K+ A+LD+G++++ PQ+ ++ L A +G +V+ C + + D+
Sbjct: 195 --KSNAILDTGTSLVLVPQQTYHNLLNTLSAKL--QNGYFVVACKSGSLPNINILIGDKV 250
Query: 342 FYFDFGELKLKVPIHDLLYLPESGQNYCGLAIIASGEE-WILGDLVLKSAYVVYDLDNLE 400
F + ++V + + C LAI W+LGD+ L+ Y V+D
Sbjct: 251 FPLTSSDYIMEVLL--------DRKPACVLAIAPINRGFWVLGDIFLRRYYTVFDATEKR 302
Query: 401 ISIAQVK 407
I +A+ K
Sbjct: 303 IGLAKAK 309
>Hs4758754 [O] KOG1339 Aspartyl protease
Length = 420
Score = 82.4 bits (202), Expect = 1e-15
Identities = 92/369 (24%), Positives = 150/369 (39%), Gaps = 67/369 (18%)
Query: 54 NPQDYFYTVELGVGTPSQKINCIFDTGSSDLWVPAKSNPFCLGNKLDTNGTNEFHGTEIT 113
N +D Y E+G+GTP Q FDTGSS+LWVP++ F
Sbjct: 72 NYRDVQYFGEIGLGTPPQNFTVAFDTGSSNLWVPSRRCHFF------------------- 112
Query: 114 PILDCDKIGVFDPGSSYSLSATGYNFSTQYFDGSYSDGFWVVDDISIADQQ--------- 164
+ C FDP +S S A G F+ QY G DG D ++I +
Sbjct: 113 -SVPCWLHHRFDPKASSSFQANGTKFAIQYGTGRV-DGILSEDKLTIGGIKGASVIFGEA 170
Query: 165 --VPDLQFAVANISSAPSGVLGVGLPRLEAVRGYDGAPNANYDNFPQTLKSNRLINRVLY 222
P L FA A+ G+LG+G P L +V G + L L+++ ++
Sbjct: 171 LWEPSLVFAFAHF----DGILGLGFPIL-SVEGVRPPMD--------VLVEQGLLDKPVF 217
Query: 223 SLYF--DSGDLESGTVLFGGIDEKKYDGVLYTLPLVNIYEQIDEPAAFDITLQGLGIRSE 280
S Y D + + G ++ GG D Y L +P + PA + I ++ + +
Sbjct: 218 SFYLNRDPEEPDGGELVLGGSDPAHYIPPLTFVP-------VTVPAYWQIHMERVKVG-- 268
Query: 281 SNCKDTVIAHKKAPALLDSGSTIMGAPQEALESIAQELGAAFSESDGLYVLDCPASNDDR 340
+ K A+LD+G++++ P E + ++ +G G Y++ C
Sbjct: 269 ---PGLTLCAKGCAAILDTGTSLITGPTEEIRALHAAIG-GIPLLAGEYIILCSEIPKLP 324
Query: 341 TFYFDFGELKLKVPIHD-LLYLPESGQNYCGLAIIA------SGEEWILGDLVLKSAYVV 393
F G + + HD ++ +G C A +G WILGD+ L + V
Sbjct: 325 AVSFLLGGVWFNLTAHDYVIQTTRNGVRLCLSGFQALDVPPPAGPFWILGDVFLGTYVAV 384
Query: 394 YDLDNLEIS 402
+D +++ S
Sbjct: 385 FDRGDMKSS 393
>Hs4503143 [O] KOG1339 Aspartyl protease
Length = 412
Score = 81.6 bits (200), Expect = 2e-15
Identities = 89/381 (23%), Positives = 149/381 (38%), Gaps = 74/381 (19%)
Query: 54 NPQDYFYTVELGVGTPSQKINCIFDTGSSDLWVPAKSNPFCLGNKLDTNGTNEFHGTEIT 113
N D Y E+G+GTP Q +FDTGSS+LWVP+ H
Sbjct: 73 NYMDAQYYGEIGIGTPPQCFTVVFDTGSSNLWVPS------------------IH----C 110
Query: 114 PILD--CDKIGVFDPGSSYSLSATGYNFSTQYFDGSYSDGFWVVDDISIADQQVPDL--- 168
+LD C ++ S + G +F Y GS S G+ D +S+ Q
Sbjct: 111 KLLDIACWIHHKYNSDKSSTYVKNGTSFDIHYGSGSLS-GYLSQDTVSVPCQSASSASAL 169
Query: 169 ---------------QFAVANISSAPSGVLGVGLPRLEAVRGYDGAPNANYDNFPQTLKS 213
Q + I++ G+LG+ PR+ +DN Q
Sbjct: 170 GGVKVERQVFGEATKQPGITFIAAKFDGILGMAYPRISVNNVLPV-----FDNLMQ---- 220
Query: 214 NRLINRVLYSLYF--DSGDLESGTVLFGGIDEKKYDGVLYTLPLVNIYEQIDEPAAFDIT 271
+L+++ ++S Y D G ++ GG D K Y G L Y + A + +
Sbjct: 221 QKLVDQNIFSFYLSRDPDAQPGGELMLGGTDSKYYKGSLS-------YLNVTRKAYWQVH 273
Query: 272 LQGLGIRSESNCKDTVIAHKKAPALLDSGSTIMGAPQEALESIAQELGAAFSESDGLYVL 331
L + + S + + A++D+G+++M P + + + + +GA G Y++
Sbjct: 274 LDQVEVAS-----GLTLCKEGCEAIVDTGTSLMVGPVDEVRELQKAIGAV-PLIQGEYMI 327
Query: 332 DCPASNDDRTFYFDFGELKLKVPIHDL-LYLPESGQNYCGLAIIA------SGEEWILGD 384
C + G K+ D L + ++G+ C + SG WILGD
Sbjct: 328 PCEKVSTLPAITLKLGGKGYKLSPEDYTLKVSQAGKTLCLSGFMGMDIPPPSGPLWILGD 387
Query: 385 LVLKSAYVVYDLDNLEISIAQ 405
+ + Y V+D DN + A+
Sbjct: 388 VFIGRYYTVFDRDNNRVGFAE 408
>7300255 [O] KOG1339 Aspartyl protease
Length = 395
Score = 81.3 bits (199), Expect = 3e-15
Identities = 88/375 (23%), Positives = 155/375 (40%), Gaps = 68/375 (18%)
Query: 46 SKSFESKLNPQDYFYTVELGVGTPSQKINCIFDTGSSDLWVPAKSNPFCLGNKLDTNGTN 105
+++ +++LN + Y + +G+P Q N +FDTGS++LWVP+
Sbjct: 70 TETLDNRLNLE---YAGPISIGSPGQPFNMLFDTGSANLWVPS----------------- 109
Query: 106 EFHGTEITP-ILDCDKIGVFDPGSSYSLSATGYNFSTQYFDGSYSDGFWVVDDISIADQQ 164
E +P + C ++ +S + G FS Y GS S G D ++I
Sbjct: 110 ----AECSPKSVACHHHHRYNASASSTFVPDGRRFSIAYGTGSLS-GRLAQDTVAIGQLV 164
Query: 165 VPDLQFAVANISSAP-------SGVLGVGLPRLEAVRGYDGAPNANYDNFP--QTLKSNR 215
V + F +A P +G++G+G P A P +++ +
Sbjct: 165 VQNQTFGMATHEPGPTFVDTNFAGIVGLGF-----------RPIAELGIKPLFESMCDQQ 213
Query: 216 LINRVLYSLYF--DSGDLESGTVLFGGIDEKKYDGVLYTLPLVNI-YEQIDEPAAFDITL 272
L++ ++S Y + + + G +LFGG+D+ K+ G L +PL + Y Q D+ +
Sbjct: 214 LVDECVFSFYLKRNGSERKGGELLFGGVDKTKFSGSLTYVPLTHAGYWQF----PLDV-I 268
Query: 273 QGLGIRSESNCKDTVIAHKKAPALLDSGSTIMGAPQEALESIAQELGAAFSESDGLYVLD 332
+ G R N A+ D+G++++ AP I LG S+ Y+L+
Sbjct: 269 EVAGTRINQN----------RQAIADTGTSLLAAPPREYLIINSLLG-GLPTSNNEYLLN 317
Query: 333 CPASNDDRTFYFDFGELKLKVPIHDLLY--LPESGQNYCGLAI-IASGEEWILGDLVLKS 389
C + F G + + D + + G + C A + E WILGD+ +
Sbjct: 318 CSEIDSLPEIVFIIGGQRFGLQPRDYVMSATNDDGSSICLSAFTLMDAEFWILGDVFIGR 377
Query: 390 AYVVYDLDNLEISIA 404
Y +D I A
Sbjct: 378 YYTAFDAGQRRIGFA 392
>7296074 [O] KOG1339 Aspartyl protease
Length = 393
Score = 80.9 bits (198), Expect = 4e-15
Identities = 80/356 (22%), Positives = 147/356 (40%), Gaps = 60/356 (16%)
Query: 57 DYFYTVELGVGTPSQKINCIFDTGSSDLWVPAKSNPFCL---GNKLDTNGTNEFHGTEIT 113
++F V +G Q FDTGSSD WVP+ FC+ GNK
Sbjct: 87 NFFGVVSVG----DQSFTMQFDTGSSDFWVPSSHCRFCIKTCGNKF-------------- 128
Query: 114 PILDCDKIGVFDPGSSYSLSATGYNFSTQYFDGSYSDGFWVVDDISIADQQVPDLQFAVA 173
F +S S ++G FS Y GS G D++ D ++ + +
Sbjct: 129 ----------FRKSNSKSFRSSGTPFSITYGSGSVK-GIVASDNVGFGDLKIQNQGIGLV 177
Query: 174 NISSAPS---GVLGVGLPRLEAVRGYDGAPNANYDNFPQTLKSNRLINRVLYSLYFDSGD 230
NIS + S G+ G +L + + +F Q + +L+ + ++S + SG
Sbjct: 178 NISDSCSVFDGIAGFAFQQLSMTK--------SVPSFQQMI-DQQLVEQPIFSFHLKSGS 228
Query: 231 LESGTVLFGGIDEKKYDGVLYTLPLVNIYEQIDEPAAFDITLQGLGIRSESNCKDTVIAH 290
+ G+++ GG + Y G L Y + E + L + + + + + + +
Sbjct: 229 SDGGSMILGGSNSSLYYGPL-------TYTNVTEAKYWSFKLDFIAVHGKGS-RSSRTGN 280
Query: 291 KKAPALLDSGSTIMGAPQEALESIAQELGAAFSESDGLYVLDCPASNDDRTFYFDFGELK 350
K A++D+G++++ P + I +++GA +++ LY + C + F +
Sbjct: 281 K---AIMDTGTSLIVGPVLEVLYINKDIGAEHNKTYNLYTVACESIPQLPIIVFGIAGKE 337
Query: 351 LKVPIHDLLYLPESGQNYCGLAI--IASGEEWILGDLVLKSAYVVYDLDNLEISIA 404
V H + + N+C A + + WILGD ++ YV +D + IA
Sbjct: 338 FFVKPHTYVIRYD---NFCFSAFMDMLGLQYWILGDAFMRENYVEFDWARRRMGIA 390
>CE09542 [O] KOG1339 Aspartyl protease
Length = 389
Score = 80.5 bits (197), Expect = 6e-15
Identities = 85/375 (22%), Positives = 146/375 (38%), Gaps = 85/375 (22%)
Query: 57 DYFYTVELGVGTPSQKINCIFDTGSSDLWVPAKSNPFCLGNKLDTNGTNEFHGTEITPIL 116
D+ Y + +GTP Q + DTGSS+LW+P P C N
Sbjct: 68 DFEYLGNITIGTPDQGFIVVLDTGSSNLWIPG---PTCKTN------------------- 105
Query: 117 DCDKIGVFDPGSSYSLSATGYNFSTQYFDGSYSDGFWVVDDISIA---DQQ--VPDLQFA 171
C FD +S + G +++ QY G + G D + D Q VP F
Sbjct: 106 -CKTKSKFDSTASSTFVKNGKSWTIQYGSGDAA-GILGQDTVRFGAKGDSQLSVPTTTFG 163
Query: 172 VANISSAP------SGVLGVGLPRLEAVRGYDGA--PNANYDNFPQTLKSNRLINRVLYS 223
+A+ SA G+LG+ L DG P N N ++++ L+S
Sbjct: 164 IASKISADFKNDATDGILGLAFTSLAV----DGVVPPLINAIN-------QGILDQPLFS 212
Query: 224 LYFD----SGDLESGTVLFGGIDEKKYDGVLYTLPLVNIYEQIDEPAAFDITLQGLGIRS 279
++ + + ++ G +G ID ++ Y+ + + G + S
Sbjct: 213 VWLEHRGAANNVGGGVFTYGAIDTTNCGALV-------AYQPLSSATYYQFKAAGFKLGS 265
Query: 280 ESNCKDTVIAHKKAPALLDSGSTIMGAPQEALESIAQELGAAFSESDGLYVLDCPASNDD 339
SN K + + D+G++ +G PQ ++ +A+ GA + + + +Y +DC A
Sbjct: 266 YSNTKTVDV-------ISDTGTSFLGGPQSVVDGLAKAAGATYDDFNEVYFIDCAAQP-- 316
Query: 340 RTFYFDFGELKLKV-----PIHDLLYLPESGQNYCGLAII-----ASGEEWILGDLVLKS 389
G L + + I + Y+ ++G C A G WILGD ++
Sbjct: 317 -------GTLDITIGTNTYSIQPVNYIVDAGNGQCLFAAFPFDFGGFGPSWILGDPFIRQ 369
Query: 390 AYVVYDLDNLEISIA 404
+YD+ N + A
Sbjct: 370 YCNIYDIGNKRMGFA 384
>CE16843 [O] KOG1339 Aspartyl protease
Length = 394
Score = 80.1 bits (196), Expect = 7e-15
Identities = 89/376 (23%), Positives = 155/376 (40%), Gaps = 69/376 (18%)
Query: 56 QDYFYTVELGVGTP-----SQKINCIFDTGSSDLWVPAKSNPFCLGNKLDTNGTNEFHGT 110
+D+ Y + +GTP Q + DTGSS++WVP S K ++ GT
Sbjct: 62 RDFAYFGNITLGTPIESTAEQTFLVVLDTGSSNVWVPDNSCGID-DKKSACTYKKKYFGT 120
Query: 111 EITPILDCDKIGVFDPGSSYSLSATGYNFSTQYFDGSYSDGFWVVDDISIADQQ--VPDL 168
+ S S G FS Y GS S G++ D + +D +
Sbjct: 121 D-----------------SSSYEKDGTPFSISYGTGSAS-GYFGKDTLCFSDTTLCIKSQ 162
Query: 169 QFAVANISSAP-------SGVLGVGLPRLEAVRGYDGAPNANYDNFPQTLKSNRLINRVL 221
F AN + AP G+LG+G L A ++ F ++ L++ +
Sbjct: 163 IFGQAN-NIAPFFANQEIDGILGLGFTDL--------AVHSVPPPFVNAVEQG-LVDEPI 212
Query: 222 YSLYFDSGDLES----GTVLFGGIDEKKYDGVLYTLPLVNIYEQIDEPAAFDITLQGLGI 277
+++Y + ++ G +GG D ++ +PL + A + +QG+GI
Sbjct: 213 FTVYLEHHGIKKEASGGYFTYGGEDPDHCGEIITWIPLT-------KAAYWQFRMQGIGI 265
Query: 278 RSESNCKDTVIAHKKA-PALLDSGSTIMGAPQEALESIAQELGAAFSESDGLYVLDCPAS 336
D V HK + D+G++ +G P + ++ IA + GA + E YV+ C
Sbjct: 266 -------DNVNEHKNGWEVISDTGTSFIGGPGKVIQDIANKYGATYDEYSDSYVIPCSEI 318
Query: 337 NDDRTFYFDFGELKLKVPIHDLLYLPESGQNYCGLAII-----ASGEEWILGDLVLKSAY 391
+ R+ +L ++ +L+ P+S + C L + G WILGD ++
Sbjct: 319 KNLRSLKMKINDLTFEIDPINLVAHPDSSE--CDLTLFDMYGGGFGPSWILGDPFIRQFC 376
Query: 392 VVYDLDNLEISIAQVK 407
++D+ N I +A K
Sbjct: 377 NIHDIKNKRIGLAHSK 392
>CE21685 [O] KOG1339 Aspartyl protease
Length = 829
Score = 78.2 bits (191), Expect = 3e-14
Identities = 98/379 (25%), Positives = 154/379 (39%), Gaps = 83/379 (21%)
Query: 57 DYFYTVELG---VGTPSQKINCIFDTGSSDLWVPAKS--NPFCLGNKLDTNGTNEFHGTE 111
DY V LG VGTP Q ++ + DTGS+++WV S N FC G + +N T +
Sbjct: 497 DYSDEVYLGNFTVGTPPQPVSLVLDTGSANMWVIDASCDNMFCNG-WIGSNYTRQ----- 550
Query: 112 ITPILDCDKIGVFDPGSSYSLSATGYNFSTQYFDGSYS-----DGFWVVDDISIADQQVP 166
FD S S S FS QY G S D + ++I Q++
Sbjct: 551 -----------KFDTSKSSSFSRENRKFSIQYGKGLCSGYLGTDTVGLGGGLTIRKQELG 599
Query: 167 -----DLQFAVANISSAPSGVLGVGLPRLEAVRGYDGAPNANYDNFPQTLKSNRLINRV- 220
D+ FAV + G+ G+ P L D +++ LI+++
Sbjct: 600 IANKLDVDFAVQPM----DGIFGLAWPALAV------------DQITPPMQN--LISQLD 641
Query: 221 --LYSLYFD-----SGDLESGTVLFGGIDEKKYD-GVLYTLPLVNIYEQIDEPAAFDITL 272
++S++ D S +G + +GGID K D GV Y Y Q +
Sbjct: 642 VPVFSVWLDRKIQASHGGSAGMITYGGIDTKNCDAGVTYVPLTAKTYWQ--------FKM 693
Query: 273 QGLGIRSESNCKDTVIAHKKAPALLDSGSTIMGAPQEALESIAQELGAAFSESDGLYVLD 332
G + + S + + D+GS+ + AP + IA + A + E + +Y +
Sbjct: 694 DGFAVGTYSQ-------YGYNQVISDTGSSWISAPYAMINDIATQTHATWDEMNEIYTVK 746
Query: 333 CPASNDDRTFYFDFGELKLKVPIHDLLYLPESG--QNYCGLAI---IAS--GEEWILGDL 385
C F G P+ + Y+ + G + C LAI +AS G WILGD+
Sbjct: 747 CSTMKTQPDLVFTIGGALF--PVKSVEYILDIGLDEGKCALAISPLMASGFGPSWILGDV 804
Query: 386 VLKSAYVVYDLDNLEISIA 404
++ +YD+ N I A
Sbjct: 805 FIRQYCNIYDIGNARIGFA 823
Score = 72.8 bits (177), Expect = 1e-12
Identities = 80/345 (23%), Positives = 134/345 (38%), Gaps = 54/345 (15%)
Query: 42 LQKRSKSFESKLNPQDYFYTVELGVGTPSQKINCIFDTGSSDLWV--PAKSNPFCLGNKL 99
LQ+ + + ++ D Y + VGTP Q + + DT S++LWV A ++ C GN
Sbjct: 50 LQQLNTGSQPLIDYYDDMYLANITVGTPPQPASVVLDTASANLWVIDAACNSQACNGNP- 108
Query: 100 DTNGTNEFHGTEITPILDCDKIGVFDPGSSYSLSATGYNFSTQYFDGSYSDGFWVVDDIS 159
G+ T F+P S + FS QY G+ S G+ D +
Sbjct: 109 ---------GSGYTK-------QKFNPNKSSTFVKGTRRFSIQYGSGT-SSGYLGTDVLQ 151
Query: 160 IADQQVPDLQFAVAN-----ISSAP-SGVLGVGLPRLEAVRGYDGAPNANYDNFPQTLKS 213
+ V +F VA + S P G+ G+G P + + N L S
Sbjct: 152 LGGLTVKAQEFGVATNLGSVLGSEPMDGIFGLGWPAISVDQVTPPMQN---------LIS 202
Query: 214 NRLINRVLYSLYFD-----SGDLESGTVLFGGIDEKKYDGVLYTLPLVNIYEQIDEPAAF 268
+ ++ L+S++ D S G + +G +D K D + Y + +
Sbjct: 203 QKQLDAPLFSIWVDRKLQVSQGGTGGLITYGAVDTKNCDAQVN-------YVALSSKTYW 255
Query: 269 DITLQGLGIRSESNCKDTVIAHKKAPALLDSGSTIMGAPQEALESIAQELGAAFSESDGL 328
+ G+ I + + K + A+ D+GS +G P L +I Q+ A + + +
Sbjct: 256 QFPMDGVAIGNYAMMK-------QEQAISDTGSAWLGLPNPVLNAIVQQTKATYDWNYEI 308
Query: 329 YVLDCPASNDDRTFYFDFGELKLKVPIHDLLYLPESGQNYCGLAI 373
Y LDC F G ++ V + + G C LAI
Sbjct: 309 YTLDCSTMQTQPDLVFTIGGMQYPVKSIEYILDLGLGNGRCVLAI 353
>7296075 [O] KOG1339 Aspartyl protease
Length = 410
Score = 77.0 bits (188), Expect = 6e-14
Identities = 81/355 (22%), Positives = 142/355 (39%), Gaps = 64/355 (18%)
Query: 60 YTVELGVGTPSQKINCIFDTGSSDLWVPAKSNPFCLGNKLDTNGTNEFHGTEITPILDCD 119
Y LG G P Q + + DTGS++LWV + P + C
Sbjct: 90 YYTTLGFGNPPQDLKVLIDTGSANLWVLSSKCP--------------------DSVAPCA 129
Query: 120 KIGVFDPGSSYSLSATGYNFSTQYFDGSYS-----DGFWVVDDISIADQQVPDLQFA--- 171
++ +S + A F+ Y S GF D ++ A + + FA
Sbjct: 130 NRIKYNSSASTTYRAINTAFNIAYGSNSEEGPIALSGFQSQDTVNFAGYSIKNQIFAEIT 189
Query: 172 ----VANISSAPSGVLGVGLPRLEAVRGYDGAPNANYDNFPQTLKSNRLINRVLYSLYFD 227
A + S G+LG+G + A N+ F L + L+NR ++S+Y +
Sbjct: 190 NAPETAFLKSQLDGILGLGFASI--------AINSITPPF-YNLMAQGLVNRSVFSIYLN 240
Query: 228 ---SGDLESGTVLFGGIDEKKYDGVLYTLPLVNIYEQIDEPAAFDITLQGLGIRSESNCK 284
+ + G ++ GG D Y G L +P + + T+ + C+
Sbjct: 241 RNGTNAINGGELILGGSDSGLYSGCLTYVP-------VSSAGYWQFTMTSANLNGFQFCE 293
Query: 285 DTVIAHKKAPALLDSGSTIMGAPQEALESIAQELGAAF-SESDGLYVLDCPASNDDRTFY 343
+ A+LD G++++ P++ L++I Q LG + S+G++++DC + D
Sbjct: 294 N-------CEAILDVGTSLIVVPEQVLDTINQILGVLNPTASNGVFLVDCSSIGDLPDIV 346
Query: 344 FDFGELKLKVPIHDLLYLPESGQNYC--GLAIIASGEEWILGDLVLKSAYVVYDL 396
F + K P+ Y+ G N C G + ILG++ L + Y YD+
Sbjct: 347 FTVA--RRKFPLKSSDYVLRYG-NTCVSGFTSMNGNSLLILGEIFLGAYYTTYDI 398
>At1g69100 [O] KOG1339 Aspartyl protease
Length = 343
Score = 76.6 bits (187), Expect = 8e-14
Identities = 81/358 (22%), Positives = 147/358 (40%), Gaps = 64/358 (17%)
Query: 48 SFESKLNPQDYFYTVELGVGTPSQKINCIFDTGSSDLWVPAKSNPFCLGNKLDTNGTNEF 107
SF N + E+ VG+P QK N +FDTGS+DLWVP+K P +K + +
Sbjct: 35 SFGGLKNFDGVVFYGEISVGSPPQKFNVVFDTGSTDLWVPSKEWPEETDHK---HPKFDK 91
Query: 108 HGTEITPILDCDKIGV-FDPGSSYSLSATGYNFSTQYFDGSYSDGFWVVDDISIADQQVP 166
++ ++ ++ + ++ GS + A + + G V+ + + P
Sbjct: 92 DASKTCRLMKGGEVNIAYETGSVVGILA----------QDNVNVGGVVIKSQDLFLARNP 141
Query: 167 DLQFAVANISSAPSGVLGVGLPRLEAVRGYDGAPNANYDNFPQTLKSNRLINRVLYSLYF 226
D F GV+G+G+ A G
Sbjct: 142 DTYFRSVKFD----GVIGLGIKSSRAQGSVTG---------------------------- 169
Query: 227 DSG-DLESGTVLFGGIDEKKYDGVLYTLPLVNIYEQIDEPAAFDITLQGLGIRSESNCKD 285
D G D G ++FGG D K++ G +P+ + D+ ++ + + N D
Sbjct: 170 DGGEDPNGGQIMFGGFDPKQFKGEHVYVPM----KLSDDRWKIKMSKIYINGKPAINFCD 225
Query: 286 TVIAHKKAPALLDSGSTIMGAPQEALESIAQELGAAFSESDGLYVLDCPASNDDRTFYFD 345
V + A++DSGST + P EA+ I +E+GA ++ C YF+
Sbjct: 226 DV----ECTAMVDSGSTDIFGPDEAVGKIYKEIGAT------KVIIRCEQFPALPDIYFE 275
Query: 346 FGELKLKVPIHDLLYLPESGQNYCGLAIIAS---GEEWILGDLVLKSAYVVYDLDNLE 400
G L++ HD + + + + C L I+ S ++W+LG+ + + V+D +++
Sbjct: 276 IGGKHLRLTKHDYVEVKTNPKKRCRLRIVKSKNRRKDWVLGEAFMTKFHTVFDYGDVK 333
>CE11478 [O] KOG1339 Aspartyl protease
Length = 383
Score = 76.3 bits (186), Expect = 1e-13
Identities = 90/379 (23%), Positives = 149/379 (38%), Gaps = 59/379 (15%)
Query: 42 LQKRSKSFESKLNPQDYFYTVELGVGTPSQKINCIFDTGSSDLWVPAKSNPFCLGNKLDT 101
LQ+ S ES + D +YTV + +GTP+Q DT SS+LWV F + K
Sbjct: 44 LQQLSTGNESIYDHFDEYYTVSVRIGTPAQHFEVALDTTSSNLWV------FGVECK--- 94
Query: 102 NGTNEFHGTEITPILDCDKIGVFDPGSSYSLSATGYNFSTQYFDGSYSDGFWVVDDISIA 161
++ +L +I ++ +S + A NF + DG S G D+I A
Sbjct: 95 --------SQSCQVLKYIRIREYNRTASSTFIAGTSNFVLPFNDGDVS-GDLGKDNIQFA 145
Query: 162 DQQVPDLQFAVANISSAPS-----GVLGVGLPRLEAVRGYDGAPNANYDNFPQTLKSNRL 216
++ + F + ++ S GVLG+G P +G + PQ
Sbjct: 146 GSKIQNQDFGIGTDATRLSGVTFDGVLGLGWP----ATALNGTSTTMQNLLPQ------- 194
Query: 217 INRVLYSLYFDSGDLESGTV----LFGGIDEKKYDGVLYTLPLVNIYEQIDEPAAFDITL 272
+++ L++ YF + +GTV FG ID + Y ++ + + ++
Sbjct: 195 LDQPLFTTYFTKSSVHNGTVGGEITFGAIDTTHCQSQIN-------YVRLAYDSLWSYSI 247
Query: 273 QGLGIRSES-NCKDTVIAHKKAPALLDSGSTIMGAPQEALESIAQELGAAFSESDGLYVL 331
G + S N DT A+ D+ S+ G P L I GA + + Y L
Sbjct: 248 DGFSFGNYSRNQTDT--------AIPDTTSSYTGVPNLVLAEIVIATGAQYDWNHQAYTL 299
Query: 332 DCPASNDDRTFYFDFGELKLKVPIHDLLYLPESGQNYCGLAIIA-----SGEEWILGDLV 386
C ++ F G V + + C L++ SG W+ GD
Sbjct: 300 PCSSTATLPDLVFTIGGNSYNVRAVEYVVNLNLPNGQCALSLFGTFSSPSGPLWVFGDNF 359
Query: 387 LKSAYVVYDLDNLEISIAQ 405
L+S ++D N I +A+
Sbjct: 360 LRSYCHIFDFGNSRIGLAK 378
>7296076 [O] KOG1339 Aspartyl protease
Length = 405
Score = 75.5 bits (184), Expect = 2e-13
Identities = 88/380 (23%), Positives = 153/380 (40%), Gaps = 62/380 (16%)
Query: 37 PADRSLQKRSKSFESKLNPQDYFYTVELGVGTPSQKINCIFDTGSSDLWVPAKSNPFCLG 96
P+ S+ S+ + +N Y+Y + +G+GTP Q +FDTGS++LWVP+ CL
Sbjct: 73 PSQTSVDYTSEELGNSMNM--YYYGL-IGIGTPEQYFKVVFDTGSANLWVPSAQ---CL- 125
Query: 97 NKLDTNGTNEFHGTEITPILDCDKIGVFDPGSSYSLSATGYNFSTQYFDGSYSDGFWVVD 156
T++ C + ++ +S + ++G NFS QY GS S G+ +D
Sbjct: 126 ------------ATDVA----CQQHNQYNSSASSTFVSSGQNFSIQYGTGSVS-GYLAID 168
Query: 157 DISIADQQVPDLQFAVANISSAPS-------GVLGVGLPRLEAVRGYDGAPNANYDNFPQ 209
++I + + F A S G+LG+G ++ D Y+
Sbjct: 169 TVTINGLAIANQTFGEAVSQPGASFTDVAFDGILGMGYQQI----AEDNVVPPFYN---- 220
Query: 210 TLKSNRLINRVLYSLYF--DSGDLESGTVLFGGIDEKKYDGVLYTLPLVNIYEQIDEPAA 267
L LI+ ++ Y + ++ G + GG D+ G + P+ + + A
Sbjct: 221 -LYEEGLIDEPVFGFYLARNGSAVDGGQLTLGGTDQNLIAGEMTYTPVTQ--QGYWQFAV 277
Query: 268 FDITLQGLGIRSESNCKDTVIAHKKAPALLDSGSTIMGAPQEALESIAQELGAAFSESDG 327
+IT G I S C+ A+ D+G++++ AP A + +G + D
Sbjct: 278 NNITWNGTVI--SSGCQ----------AIADTGTSLIAAPSAAYIQLNNLIGGVPIQGD- 324
Query: 328 LYVLDCPASNDDRTFYFDFGELKLKVP--IHDLLYLPESGQNYCGLAIIASGEE-WILGD 384
Y + C + + G +P ++ Y E C G WILGD
Sbjct: 325 -YYVPCSTVSSLPVLTINIGGTNFYLPPSVYIQTY-TEGNYTTCMSTFTDIGTGFWILGD 382
Query: 385 LVLKSAYVVYDLDNLEISIA 404
+ L Y +D + A
Sbjct: 383 VFLGQYYSEFDFGQNRVGFA 402
>CE09539 [O] KOG1339 Aspartyl protease
Length = 393
Score = 75.1 bits (183), Expect = 2e-13
Identities = 85/374 (22%), Positives = 149/374 (39%), Gaps = 82/374 (21%)
Query: 57 DYFYTVELGVGTPSQKINCIFDTGSSDLWVPAKSNPFCLGNKLDTNGTNEFHGTEITPIL 116
D+ Y + +GTP Q + DTGSS+LWVP P C G+ G E+ T+
Sbjct: 70 DFEYLGNITIGTPPQPFLVVLDTGSSNLWVP---GPSCDGS---CKGKREYQSTK----- 118
Query: 117 DCDKIGVFDPGSSYSLSATGYNFSTQYFDGSYSDGFWVVDDI---SIADQQ--VPDLQFA 171
S + A G + QY G+ + G+ D + ++ ++Q VP F
Sbjct: 119 ------------SSTFKANGKPWQIQYGSGN-AKGYLGEDTVAFGAVTEKQLPVPSTTFG 165
Query: 172 VA-NISS-----APSGVLGVGLPRLEAVRGYDGAPNANYDNFPQTLKSNRLINRVLYSLY 225
+A +ISS A G+LG+ L NA + L+++ L++++
Sbjct: 166 IATHISSDFKNDAAEGILGLAFTSLAVDHVVPPLINA---------INQGLLDQPLFTVW 216
Query: 226 FD----SGDLESGTVLFGGIDEKKYDGVLYTLPLVNIYEQIDEPAAFDITLQGLGIRSES 281
+ + D+ G +G +D V+ Y+ + + + S S
Sbjct: 217 LEHKGSANDVGGGVFTYGAVDTTNCGPVI-------AYQPLSSATYYQFVADSFKLGSYS 269
Query: 282 NCKDTVIAHKKAPALLDSGSTIMGAPQEALESIAQELGAAFSESDGLYVLDCPASNDDRT 341
N KK + D+G++ +G P+ + +A LGA + +D Y + C
Sbjct: 270 N-------SKKYQVISDTGTSFLGGPKAVVAGLASALGATYHSNDDSYYVPCAT------ 316
Query: 342 FYFDFGELKLKV-----PIHDLLYLPESGQ-NYCGLAIIA-----SGEEWILGDLVLKSA 390
+ G L + + I+ + Y+ + G + C A A G WILGD ++
Sbjct: 317 ---NIGTLDITIGGKVYSINPVNYIVDVGMGDTCVFAAFAFNNFGFGPAWILGDPFIRQF 373
Query: 391 YVVYDLDNLEISIA 404
+YD+ + A
Sbjct: 374 CNIYDIGGQRMGFA 387
>7300253 [O] KOG1339 Aspartyl protease
Length = 465
Score = 75.1 bits (183), Expect = 2e-13
Identities = 86/362 (23%), Positives = 135/362 (36%), Gaps = 57/362 (15%)
Query: 54 NPQDYFYTVELGVGTPSQKINCIFDTGSSDLWVPAKSNPFCLGNKLDTNGTNEFHGTEIT 113
N + YT ++ +GTP QK + DTGSS++WVP P C
Sbjct: 144 NTANMEYTCKMNIGTPKQKFTVLPDTGSSNIWVP---GPHCKSKA--------------- 185
Query: 114 PILDCDKIGVFDPGSSYSLSATGYNFSTQYFDGSYSDGFWVVDDISIADQQVPDLQFAVA 173
C K + P S + G +F+ Y GS + G D + IA V + FA+
Sbjct: 186 ----CKKHKQYHPAKSSTYVKNGKSFAITYGSGSVA-GVLAKDTVRIAGLVVTNQTFAMT 240
Query: 174 N-------ISSAPSGVLGVGLPRLEAVRGYDGAPNANYDNFPQTLKSNRLINRVLYSLYF 226
++S G+LG+ GY N Q + S +I +++
Sbjct: 241 TKEPGTTFVTSNFDGILGL---------GYRSIAVDNVKTLVQNMCSEDVITSCKFAICM 291
Query: 227 DSGDLES--GTVLFGGIDEKKYDGV-LYTLPLVNIYEQIDEPAAFDITLQGLGIRSESNC 283
G S G ++FG + Y G YT Y + + + TLQ + +
Sbjct: 292 KGGGSSSRGGAIIFGSSNTSAYSGSNSYT------YTPVTKKGYWQFTLQDIYVGGTK-- 343
Query: 284 KDTVIAHKKAPALLDSGSTIMGAPQEALESIAQELGAAFSESDGLYVLDCPASNDDRTFY 343
A++DSG++++ AP I + +G + S G + C D TF
Sbjct: 344 -----VSGSVQAIVDSGTSLITAPTAIYNKINKVIGCR-ATSSGECWMKCAKKIPDFTFV 397
Query: 344 FDFGELKLKVPIHDLLYLPESGQNYCGLAII-ASGEEWILGDLVLKSAYVVYDLDNLEIS 402
+ +K L G+ C A+ E ILGD ++ +DL N I
Sbjct: 398 IAGKKFVVKGNKMKLKVRTNRGRTVCISAVTEVPDEPVILGDAFIRHFCTEFDLANNRIG 457
Query: 403 IA 404
A
Sbjct: 458 FA 459
>YDR349c [O] KOG1339 Aspartyl protease
Length = 596
Score = 74.3 bits (181), Expect = 4e-13
Identities = 68/266 (25%), Positives = 114/266 (42%), Gaps = 29/266 (10%)
Query: 170 FAVANISSAPSGVLGVGLPRLEAVRGYDGAPNANYDNFPQTLKSNRLINRVLYSLYFDSG 229
F + + + SG+LG+ D + F LK +I YSL+ +G
Sbjct: 179 FDIQSSNFKTSGLLGLSGKVTNPGNAIDSSQYTEQSYFLSLLKDADIIESSSYSLWL-AG 237
Query: 230 DLES-----------GTVLFGGIDEKKYDGVLYTLPLVNIYEQIDEPAAFDITLQGLG-I 277
D + G +L GG+D + G L L+ + + + + LG I
Sbjct: 238 DTSTYKTYRDPISNCGKLLLGGVDPSLFTGTLGKFDLIPYVDPVSNAVSVGYPIVPLGPI 297
Query: 278 RSESNCKDTVIAHKK---APALLDSGSTIMGAPQEALESIAQELGAAFSESDGLYVLDCP 334
SN ++ K +PALLDS S++ P + IA ++ A + ES +++ C
Sbjct: 298 YIVSNSGQSLNMTSKDFLSPALLDSTSSVSYLPTSTIIQIAVQIAATYVESLDRWLVQCS 357
Query: 335 ASNDDRTFYFDFGELKLKVPIHDLL-----------YLPESGQNYCGLAIIASGEEW--I 381
++ + F EL +++P+ DLL SGQ C L + A+ I
Sbjct: 358 IADMGVSLGFRLRELTIEIPLRDLLSSTYDTSTNSSMFFSSGQEACFLTLYANTNTGVNI 417
Query: 382 LGDLVLKSAYVVYDLDNLEISIAQVK 407
LG+ +K+ Y+ DL++ I+IAQ K
Sbjct: 418 LGEAFIKNIYMAMDLEDNTIAIAQAK 443
>At1g65240 [O] KOG1339 Aspartyl protease
Length = 475
Score = 72.4 bits (176), Expect = 2e-12
Identities = 93/382 (24%), Positives = 162/382 (42%), Gaps = 48/382 (12%)
Query: 60 YTVELGVGTPSQKINCIFDTGSSDLWVPAKSNPFCLGNKLDTN---GTNEFHGTEITPIL 116
Y ++ +G+P ++ + DTGS LW+ K P C K + N + + + + +
Sbjct: 74 YFTKIKLGSPPKEYHVQVDTGSDILWINCKPCPKC-PTKTNLNFRLSLFDMNASSTSKKV 132
Query: 117 DCDK-IGVFDPGSSYSLSATGYNFSTQYFDGSYSDGFWVVDDISIADQQVPDL------Q 169
CD F S A G ++ Y D S SDG ++ D +++ +Q DL Q
Sbjct: 133 GCDDDFCSFISQSDSCQPALGCSYHIVYADESTSDGKFIRDMLTL-EQVTGDLKTGPLGQ 191
Query: 170 FAVANISSAPSGVLGVGLPRLEAVRGYDGAPNANYDNFPQTLKSNRLINRVLYSLYFDSG 229
V S SG LG G ++ V G+ + + T + R+ + L
Sbjct: 192 EVVFGCGSDQSGQLGNGDSAVDGVMGFGQSNTSVLSQLAATGDAKRVFSHCL-------D 244
Query: 230 DLESGTVLFGGIDEKKYDGVLYTLPLVNIYEQIDEPAAFDITLQGLGIRSESNCKDTVIA 289
+++ G + G+ + P V + +++ L G+ + S I
Sbjct: 245 NVKGGGIFAVGVVDS---------PKVKTTPMVPNQMHYNVMLMGMDVDGTSLDLPRSIV 295
Query: 290 HKKAPALLDSGSTIMGAPQEALESIAQELGAAFSESDGLYVLDCP------ASNDDRTF- 342
+ ++DSG+T+ P+ +S+ + + A + L++++ ++N D F
Sbjct: 296 -RNGGTIVDSGTTLAYFPKVLYDSLIETILAR--QPVKLHIVEETFQCFSFSTNVDEAFP 352
Query: 343 --YFDFGE-LKLKVPIHDLLYLPESGQNYC------GLAIIASGEEWILGDLVLKSAYVV 393
F+F + +KL V HD L+ E + YC GL E +LGDLVL + VV
Sbjct: 353 PVSFEFEDSVKLTVYPHDYLFTLEE-ELYCFGWQAGGLTTDERSEVILLGDLVLSNKLVV 411
Query: 394 YDLDNLEISIAQVKTTSGSRIQ 415
YDLDN I A +S +I+
Sbjct: 412 YDLDNEVIGWADHNCSSSIKIK 433
>SPCC1795.09 [O] KOG1339 Aspartyl protease
Length = 521
Score = 72.0 bits (175), Expect = 2e-12
Identities = 97/405 (23%), Positives = 155/405 (37%), Gaps = 47/405 (11%)
Query: 39 DRSLQKRSKSFESK------LNPQDY-FYTVELGVGTPSQKINCIFDTGSSDLWVPAKS- 90
+ L+KR ++ L+ Q Y +YT L +G PS D W+ +
Sbjct: 39 ENQLEKRDYTYSPSGITSFPLDLQSYTYYTTTLSIGRPSISYTVAIDLDMPYTWLTYYNV 98
Query: 91 ---NPFCLGNKLDTNGTNEFHGTEITPIL---DCDKIGVFDPGSSYSLSATGYNFSTQYF 144
NP LG N ++ E+ L + D + SS+ + F +Y
Sbjct: 99 MAFNPAYLGI---VNSGTQWSTDELRYFLCKKESDSCYFGNASSSFHFVTSPSTFFIRYD 155
Query: 145 DGSYSDGFWVVDDISIADQQ-VPDLQFAVANISSAPS------GVLGVGLP-RLEAVRGY 196
D G V D +S + Q +PD QF + PS GVLG+ + ++
Sbjct: 156 DNITVAGINVQDSLSYSHYQALPDFQFGITLKEYVPSSMLPYKGVLGLAASTEINSIDYS 215
Query: 197 DGAPNANYDNFPQTLKSNRLINRVLYSLYFDSGDLESGTVLFGGIDEKKYDGVLYTLPLV 256
D + + F + L ++ +S+Y D+ +G++L G +D KY G L
Sbjct: 216 DSISSFSPPTFLEQLVKEDILAYPAFSMYLDNQG--NGSLLLGAVDTSKYQGQFVALKQT 273
Query: 257 NIYEQIDEPAAFDITLQGLGIRSESNCKDTVIAHKK--APALLDSGSTIMGAPQEALESI 314
+ T + I S T ++ A + T + P E S+
Sbjct: 274 KL------------THYAVSIYSVQFLNSTFFSNYSIITDAYFQTRETYIYLPAELAYSV 321
Query: 315 AQELGAAFSESDGLYVLDCPASNDDRTFYFDFG-ELKLKVPIHDLLYLPESGQNYCGLAI 373
GA SE G + L+C + + F FG +KVPI L+ S N C L I
Sbjct: 322 MDNAGAYLSE--GYFALNCDEIDLEAALIFQFGCNSTIKVPISLLVIGQVS--NICLLGI 377
Query: 374 IASGE-EWILGDLVLKSAYVVYDLDNLEISIAQVKTTSGSRIQTV 417
S + E +LG L ++AY Y I+I Q + S + +
Sbjct: 378 RPSTDSEIVLGLLFFRNAYTFYHQSQKMIAIGQAFYNATSNLSAI 422
>CE11480 [O] KOG1339 Aspartyl protease
Length = 474
Score = 70.9 bits (172), Expect = 4e-12
Identities = 83/380 (21%), Positives = 142/380 (36%), Gaps = 61/380 (16%)
Query: 42 LQKRSKSFESKLNPQDYFYTVELGVGTPSQKINCIFDTGSSDLWVPAKS--NPFCLGNKL 99
+Q+ S S + D +YT + +GTP+Q FDT SS+LWV + C G +
Sbjct: 135 IQQLSTGNVSFFDHFDEYYTAGVRIGTPAQHFQVAFDTTSSNLWVFGVECRSQNCHGGR- 193
Query: 100 DTNGTNEFHGTEITPILDCDKIGVFDPGSSYSLSATGYNFSTQYFDGSYSDGFWVVDDIS 159
E++ T S++ + +N +DG + G D
Sbjct: 194 -GRRDREYNRTA---------------SSTFVAGTSSFNLP---YDGGHVSGNVGKDTAQ 234
Query: 160 IADQQVPDLQFAVANISSAP-----SGVLGVGLPRLEAVRGYDGAPNANYDNFPQTLKSN 214
A + F + ++ GVLG+G P +G + PQ
Sbjct: 235 FAGFTIQSQDFGIGTAATRLFGETFDGVLGLGWP----ATALNGTSTTMQNLLPQ----- 285
Query: 215 RLINRVLYSLYFDSGDLESGT----VLFGGIDEKKYDGVLYTLPLVNIYEQIDEPAAFDI 270
+++ L++ YF ++ +GT ++FG ID + +PL + ++ +
Sbjct: 286 --LDQKLFTTYFTKSNMHNGTAGGDIMFGAIDTTHCQSQVNYVPLA-----YNSFWSYSV 338
Query: 271 TLQGLGIRSESNCKDTVIAHKKAPALLDSGSTIMGAPQEALESIAQELGAAFSESDGLYV 330
+G S + + T+ D+ S G P L I + GA + + Y
Sbjct: 339 DGFSIGTYSRTQTETTIP---------DTSSGWTGVPNVVLAGIVKATGATYDWNHQAYT 389
Query: 331 LDCPASNDDRTFYFDFGELKLKVPIHDLLYLPESGQNYCGLAIIA-----SGEEWILGDL 385
L C ++ F G V + + C L++ SG WILGD
Sbjct: 390 LPCSSTATLPDMVFTIGGNSYNVRAVEYVVNLNLPNGQCALSLFGTAASQSGPAWILGDN 449
Query: 386 VLKSAYVVYDLDNLEISIAQ 405
L+S V+D N I +A+
Sbjct: 450 FLRSYCHVFDFGNSRIGLAK 469
>7296077 [O] KOG1339 Aspartyl protease
Length = 418
Score = 70.1 bits (170), Expect = 8e-12
Identities = 88/382 (23%), Positives = 155/382 (40%), Gaps = 75/382 (19%)
Query: 41 SLQKRSKSFESKLNPQDYFYTVELGVGTP-SQKINCIFDTGSSDLWVPAKSNPFCLGNKL 99
S+ + + S E+ +N + Y V G GTP SQ + + DT S++L V S+ F + L
Sbjct: 73 SVYQTTVSKENLINSHNTEYYVTAGFGTPKSQPVTLLVDTASANLLV--YSSEFVKQSCL 130
Query: 100 DTNGTNEFHGTEITPILDCDKIGVFDPGSSYSLSATGYNFSTQYFDGSYSDGFWVVDDIS 159
+G N S + A G F Q+ G D +
Sbjct: 131 HHDGYNS--------------------SESQTYQANGSPFQIQFASQEILTGILSTDTFT 170
Query: 160 IADQQVPDLQFAVANISSAPS---------GVLGVGLPRLEAVRGYDGAPNANYDNFPQT 210
+ D + + FA I+SAP+ G++G+G + A+ G + DN
Sbjct: 171 LGDLVIKNQTFA--EINSAPTDMCKRSNFDGIIGLGFSEI-ALNGVE----TPLDN---- 219
Query: 211 LKSNRLINRVLYSLYFD---SGDLESGTVLFGGIDEKKYDGVLYTLPLVNIYEQIDEPAA 267
+ LI+ ++SLY + S G +L GG D Y G L +P + +
Sbjct: 220 ILEQGLIDEPIFSLYVNRNASDASNGGVLLLGGSDPTLYSGCLTYVP-------VSKVGF 272
Query: 268 FDITLQGLGIRSESNCKDTVIAHKKAPALLDSGSTIMGAPQEALESIAQELGAAFSE-SD 326
+ IT+ + I S+ C + A+ D G++++ P AL+ I ++LG ++ D
Sbjct: 273 WQITVGQVEIGSKKLCSN-------CQAIFDMGTSLIIVPCPALKIINKKLGIKETDRKD 325
Query: 327 GLYVLDCPASNDDRTFYFDFGELKLKVPIHDLLYLPESGQNYCGLAIIAS---------- 376
G+Y++DC + F+ G + D + L SG G + ++
Sbjct: 326 GVYIIDCKKVSHLPKIVFNIGWKDFTLNPSDYI-LNYSGTCVSGFSSLSDCNGTQTNDDS 384
Query: 377 ---GEEWILGDLVLKSAYVVYD 395
W+ GD+ + + ++D
Sbjct: 385 EDLNNIWVFGDVFFGAIFTLFD 406
>At4g04460 [O] KOG1339 Aspartyl protease
Length = 508
Score = 69.7 bits (169), Expect = 1e-11
Identities = 71/295 (24%), Positives = 117/295 (39%), Gaps = 58/295 (19%)
Query: 54 NPQDYFYTVELGVGTPSQKINCIFDTGSSDLWVPAKSNPFCLGNKLDTNGTNEFHGTEIT 113
N D Y ++ +GTP QK IFDTGSS+LW+P+ T+
Sbjct: 81 NYLDAQYYGDITIGTPPQKFTVIFDTGSSNLWIPS---------------------TKCY 119
Query: 114 PILDCDKIGVFDPGSSYSLSATGYNFSTQYFDGSYSDGFWVVDDISIADQQVPDLQFAVA 173
+ C + S S G S +Y G+ S G++ DD+ + D V + +F A
Sbjct: 120 LSVACYFHSKYKASQSSSYRKNGKPASIRYGTGAIS-GYFSNDDVKVGDIVVKEQEFIEA 178
Query: 174 N-------ISSAPSGVLGVGLPRLEAVRGYDGAPNANYDNFPQTLKSNRLINRVLYSLYF 226
+ + G+LG+G + N + L+ ++S +
Sbjct: 179 TSEPGITFLLAKFDGILGLGFKEISV---------GNSTPVWYNMVEKGLVKEPIFSFWL 229
Query: 227 DSG--DLESGTVLFGGIDEKKYDGVLYTLPLVNI-YEQIDEPAAFDITLQGLGIRSESNC 283
+ D E G ++FGG+D K + G +P+ + Y Q D D+ + G
Sbjct: 230 NRNPKDPEGGEIVFGGVDPKHFKGEHTFVPVTHKGYWQFD---MGDLQIAG--------- 277
Query: 284 KDTVIAHKKAPALLDSGSTIMGAPQEALESIAQELGAAFSESDGLYVLDCPASND 338
K T K A+ DSG++++ P + I +GA G+ +C A D
Sbjct: 278 KPTGYCAKGCSAIADSGTSLLTGPSTVITMINHAIGA-----QGIVSRECKAVVD 327
>Hs22063919 [O] KOG1339 Aspartyl protease
Length = 267
Score = 67.8 bits (164), Expect = 4e-11
Identities = 53/190 (27%), Positives = 90/190 (46%), Gaps = 23/190 (12%)
Query: 222 YSLYFDSG-----DLESGTVLFGGIDEKKYDGVLYTLPL-VNIYEQIDEPAAFDITLQGL 275
+++ FD+G D V+FGGID Y G L +P+ V Y QI + IT+ G
Sbjct: 89 FTVVFDTGSSNLDDQSGSVVIFGGIDSSYYTGSLNWVPVTVEGYWQITVDS---ITMNGE 145
Query: 276 GIRSESNCKDTVIAHKKAPALLDSGSTIMGAPQEALESIAQELGAAFSESDGLYVLDCPA 335
I C+ A++D+G++++ P + +I ++GA+ SDG V+ C A
Sbjct: 146 AIACAEGCQ----------AIVDTGTSLLTGPTSPIANIQSDIGAS-ENSDGDMVVSCSA 194
Query: 336 SNDDRTFYFDFGELKLKVPIHDLLYLPESG--QNYCGLAI-IASGEEWILGDLVLKSAYV 392
+ F ++ VP + E + G+ + SGE WILGD+ ++ +
Sbjct: 195 ISSLPDIVFTINGVQYPVPPSAYILQSEGSCISGFQGMNLPTESGELWILGDVFIRQYFT 254
Query: 393 VYDLDNLEIS 402
V+D N +I+
Sbjct: 255 VFDRANNQIT 264
>At1g11910 [O] KOG1339 Aspartyl protease
Length = 506
Score = 67.4 bits (163), Expect = 5e-11
Identities = 72/278 (25%), Positives = 113/278 (39%), Gaps = 53/278 (19%)
Query: 54 NPQDYFYTVELGVGTPSQKINCIFDTGSSDLWVPAKSNPFCLGNKLDTNGTNEFHGTEIT 113
N D Y E+ +GTP QK +FDTGSS+LWVP+ F L L + T
Sbjct: 76 NYLDAQYYGEIAIGTPPQKFTVVFDTGSSNLWVPSSKCYFSLACLLHPKYKSSRSST--- 132
Query: 114 PILDCDKIGVFDPGSSYSLSATGYNFSTQYFDGSYSDGFWVVDDISIADQQV------PD 167
+K G A ++ T G +S+ V D+ + DQ+ P
Sbjct: 133 ----YEKNG----------KAAAIHYGTGAIAGFFSNDAVTVGDLVVKDQEFIEATKEPG 178
Query: 168 LQFAVANISSAPSGVLGVGLPRLEAVRGYDGAPNANYDNFPQTLKSNRLINRVLYSLYF- 226
+ F VA G+LG+G + + A Y+ Q LI ++S +
Sbjct: 179 ITFVVAKF----DGILGLGFQEISVGK----AAPVWYNMLKQ-----GLIKEPVFSFWLN 225
Query: 227 -DSGDLESGTVLFGGIDEKKYDGVLYTLPLVNI-YEQIDEPAAFDITLQGLGIR-SESNC 283
++ + E G ++FGG+D + G +P+ Y Q D D+ + G ES C
Sbjct: 226 RNADEEEGGELVFGGVDPNHFKGKHTYVPVTQKGYWQFD---MGDVLIGGAPTGFCESGC 282
Query: 284 KDTVIAHKKAPALLDSGSTIMGAPQEALESIAQELGAA 321
A+ DSG++++ P + I +GAA
Sbjct: 283 S----------AIADSGTSLLAGPTTIITMINHAIGAA 310
>CE21683 [O] KOG1339 Aspartyl protease
Length = 320
Score = 67.0 bits (162), Expect = 6e-11
Identities = 73/315 (23%), Positives = 128/315 (40%), Gaps = 57/315 (18%)
Query: 40 RSLQKRSKSFESKLNPQDYFYTVELGVGTPSQKINCIFDTGSSDLWV--PAKSNPFCLGN 97
R+LQ + S + ++ D FY + VGTP Q + + DTGSS+LWV A ++ C G+
Sbjct: 50 RTLQLKQGS-QPFIDYMDDFYLGNISVGTPGQTLTLVLDTGSSNLWVIDAACNSEACNGD 108
Query: 98 KLDTNGTNEFHGTEITPILDCDKIGVFDPGSSYSLSATGYNFSTQYFDGSYSDGFWVVDD 157
++ FD +S + + FS Y GS S G D
Sbjct: 109 PKSGFAKHK-----------------FDTKASSTFVSETRKFSISYGSGSCS-GHLARDT 150
Query: 158 ISIADQQVPDLQFAVANISSA------PSGVLGVGLPRLEAVRGYDGAPNANYDNFPQTL 211
I++ ++ + +F VA ++ G+LG+G P L D + PQ
Sbjct: 151 ITMGGLKIDNQEFGVAETLASVFAEQPVDGILGLGWPAL----ADDKVTPPMQNLLPQ-- 204
Query: 212 KSNRLINRVLYSLYFD-----SGDLESGTVLFGGIDEKKYDGVLYTLPLVNIYEQIDEPA 266
++ +++++ D S G + +G +D + +PL
Sbjct: 205 -----LDAKVFTVWMDRKLQGSNGGNGGLITYGALDSVNCADDISYVPLT-------AKT 252
Query: 267 AFDITLQGLGIRSESNCKDTVIAHKKAPALLDSGSTIMGAPQEALESIAQELGAAFSESD 326
++ L G + S S K A + D+G++ +GAP + ++ + GA F +
Sbjct: 253 YWEFALDGFAVGSFSET-------KTAKVISDTGTSWIGAPHSIISAVVKATGAKFEWTT 305
Query: 327 GLYVLDCPASNDDRT 341
LYV+ C + T
Sbjct: 306 ELYVVPCSTMKPNLT 320
>CE20430 [O] KOG1339 Aspartyl protease
Length = 638
Score = 66.6 bits (161), Expect = 8e-11
Identities = 77/357 (21%), Positives = 139/357 (38%), Gaps = 59/357 (16%)
Query: 66 VGTPSQKINCIFDTGSSDLWVPAKSNPFCLGNKLDTNGTNEFHGTEITPILDCDKIGVFD 125
+G+P Q DT S++LWV +G+ + N+ P+L K F+
Sbjct: 68 IGSPPQSAFVFMDTTSANLWV--------MGSACTSVNCND-------PLLGIIK-HKFN 111
Query: 126 PGSSYSLSATGYNFSTQYFDGSYSDGFWVVDDISIADQQVPDLQFAVANI------SSAP 179
S S + F+ QY G S G+ D + I ++ +F VANI +
Sbjct: 112 TTKSTSFVKSNRKFNIQYGSGECS-GYLGTDTVEIGGLKIQKQEFGVANIVDYDFGTRPI 170
Query: 180 SGVLGVGLPRLEAVRGYDGAPNANYDNFPQTLKSNRLINRVLYSLYFDSGDLE-----SG 234
G+ G+ P L + N L S ++ +++++FD D + +G
Sbjct: 171 DGIFGLAWPALSVDQVTPPMQN---------LVSQNQLDAPIFTIFFDKRDPDYYYPSNG 221
Query: 235 TVLFGGIDEKKYDGVLYTLPLVNIYEQIDEPAAFDITLQGLGIRSESNCKDTVIAHKKAP 294
+ +GG+D K + + +P + + + G + + + + +
Sbjct: 222 LITYGGLDTKNCNANISYVP-------VSSKTYWQFKVDGFQVGTYNRTVN------RDQ 268
Query: 295 ALLDSGSTIMGAPQEALESIAQELGAAFSESDGLYVLDCPASNDDRTFYFDFGELKLKVP 354
A++D+GS+ G P + IA + A + +Y + C N F G K P
Sbjct: 269 AIMDTGSSWFGLPYSVIAGIATQTNATWDLYASVYTVPCSTMNSLPDLVFTIGAEKF--P 326
Query: 355 IHDLLYLPESG--QNYCGLAII-----ASGEEWILGDLVLKSAYVVYDLDNLEISIA 404
I Y+ + G C LA+ G LG++ ++ V+D+ N I A
Sbjct: 327 ISAPEYVEDVGLDDGTCALAMYGIDASGFGPSVTLGNIFIRRYCSVFDVGNARIGFA 383
>At1g62290 [O] KOG1339 Aspartyl protease
Length = 526
Score = 63.2 bits (152), Expect = 9e-10
Identities = 65/264 (24%), Positives = 103/264 (38%), Gaps = 53/264 (20%)
Query: 54 NPQDYFYTVELGVGTPSQKINCIFDTGSSDLWVPAKSNPFCLGNKLDTNGTNEFHGTEIT 113
N D Y E+ +GTP QK IFDTGSS+LWVP+ F
Sbjct: 83 NYLDAQYYGEIAIGTPPQKFTVIFDTGSSNLWVPSGKCFFS------------------- 123
Query: 114 PILDCDKIGVFDPGSSYSLSATGYNFSTQYFDGSYSDGFWVVDDISIADQQVPDLQF--- 170
L C + S + +G + Y GS S GF+ D +++ D V D +F
Sbjct: 124 --LSCYFHAKYKSSRSSTYKKSGKRAAIHYGSGSIS-GFFSYDAVTVGDLVVKDQEFIET 180
Query: 171 ----AVANISSAPSGVLGVGLPRLEAVRGYDGAPNANYDNFPQTLKSNRLINRVLYSLYF 226
+ + + G+LG+G + N + LI R ++S +
Sbjct: 181 TSEPGLTFLVAKFDGLLGLGFQEIAV---------GNATPVWYNMLKQGLIKRPVFSFWL 231
Query: 227 --DSGDLESGTVLFGGIDEKKYDGVLYTLPLVNI-YEQIDEPAAFDITLQGLGIRSESNC 283
D E G ++FGG+D K + G +P+ Y Q D ++ + G
Sbjct: 232 NRDPKSEEGGEIVFGGVDPKHFRGEHTFVPVTQRGYWQFD---MGEVLIAG--------- 279
Query: 284 KDTVIAHKKAPALLDSGSTIMGAP 307
+ T A+ DSG++++ P
Sbjct: 280 ESTGYCGSGCSAIADSGTSLLAGP 303
>CE21684 [O] KOG1339 Aspartyl protease
Length = 435
Score = 62.8 bits (151), Expect = 1e-09
Identities = 72/324 (22%), Positives = 120/324 (36%), Gaps = 44/324 (13%)
Query: 57 DYFYTVELGVGTPSQKINCIFDTGSSDLWVPAK--SNPFCLGNKLDTNGTNEFHGTEITP 114
D YT + VGTP Q + + TGS++ WV ++P C G + +F+ + +
Sbjct: 62 DEIYTANITVGTPPQSASVVMGTGSANFWVVGAGCTSPACNGFPDSGHTKLKFYSNKSSS 121
Query: 115 ILDCDKIGVFDPGSSYSLSATGYNFSTQYFDGSYSDGFWVVDDISIADQQVPDLQFAVAN 174
+D ++ F Y G+ S G+ D + + V + +FAV
Sbjct: 122 FVDLNR-----------------KFFINYPTGACS-GYLGTDVLQLGGLTVKNQEFAVTT 163
Query: 175 ISSAPSGVLGVGLPRLEAVRGYDGAPNANYDNFPQTLKSNRLINRVLYSLYFD-----SG 229
S G L+ V G P A P ++ +++L+ D S
Sbjct: 164 QISDQMGHFP-----LDGVLGLAWPPVAVDQITPPMQNLMPQLDAPIFTLWLDRVLQGSQ 218
Query: 230 DLESGTVLFGGIDEKKYDGVLYTLPLVNIYEQIDEPAAFDITLQGLGIRSESNCKDTVIA 289
G + FG ID K D + Y + + L G+ I S ++ K
Sbjct: 219 GGSGGLITFGAIDTKNCDAQVN-------YVALSSKTFWQFPLDGVAIGSYTSMK----- 266
Query: 290 HKKAPALLDSGSTIMGAPQEALESIAQELGAAFSESDGLYVLDCPASNDDRTFYFDFGEL 349
K A+ DSG + P L ++ Q+ A + ++ Y LDC F G +
Sbjct: 267 --KDQAISDSGDFGLRLPLAVLNAVIQQTKATYDWTNEFYTLDCSTMQTQPDLVFTIGGM 324
Query: 350 KLKVPIHDLLYLPESGQNYCGLAI 373
+ V + + G C LA+
Sbjct: 325 QYPVKSVEYILDLGLGNGRCVLAM 348
>At5g36260 [O] KOG1339 Aspartyl protease
Length = 478
Score = 62.8 bits (151), Expect = 1e-09
Identities = 89/395 (22%), Positives = 153/395 (38%), Gaps = 71/395 (17%)
Query: 60 YTVELGVGTPSQKINCIFDTGSSDLWVPAKSNPFC-----LGNKLD-----TNGTNEFHG 109
Y ++ +G+P ++ DTGS LWV P C LG L T+ T++ G
Sbjct: 74 YFTKIKLGSPPKEYYVQVDTGSDILWVNCAPCPKCPVKTDLGIPLSLYDSKTSSTSKNVG 133
Query: 110 TE---ITPILDCDKIGVFDPGSSYSLSATGYNFSTQYFDGSYSDGFWVVDDISIAD---- 162
E + I+ + G P S + Y DGS SDG ++ D+I++
Sbjct: 134 CEDDFCSFIMQSETCGAKKPCS----------YHVVYGDGSTSDGDFIKDNITLEQVTGN 183
Query: 163 -QQVPDLQFAVANISSAPSGVLGVGLPRLEAVRGYDGAPNANYDNFPQTLKSNRLINRVL 221
+ P Q V SG LG ++ + G+ + + + R+ + L
Sbjct: 184 LRTAPLAQEVVFGCGKNQSGQLGQTDSAVDGIMGFGQSNTSIISQLAAGGSTKRIFSHCL 243
Query: 222 YSL----YFDSGDLESGTVLFGGIDEKKYDGVLYTLPLVNIYEQIDEPAAFDITLQGLGI 277
++ F G++ES P+V + +++ L+G+ +
Sbjct: 244 DNMNGGGIFAVGEVES--------------------PVVKTTPIVPNQVHYNVILKGMDV 283
Query: 278 RSESNCKDTVIAHKKAPA--LLDSGSTIMGAPQEALESIAQELGAAFSES----DGLYVL 331
+ +A ++DSG+T+ PQ S+ +++ A +
Sbjct: 284 DGDPIDLPPSLASTNGDGGTIIDSGTTLAYLPQNLYNSLIEKITAKQQVKLHMVQETFAC 343
Query: 332 DCPASNDDRTF-----YFDFGELKLKVPIHDLLYLPESGQNYC------GLAIIASGEEW 380
SN D+ F +F+ LKL V HD L+ YC G+ +
Sbjct: 344 FSFTSNTDKAFPVVNLHFE-DSLKLSVYPHDYLFSLREDM-YCFGWQSGGMTTQDGADVI 401
Query: 381 ILGDLVLKSAYVVYDLDNLEISIAQVKTTSGSRIQ 415
+LGDLVL + VVYDL+N I A +S +++
Sbjct: 402 LLGDLVLSNKLVVYDLENEVIGWADHNCSSSIKVK 436
>CE09738 [O] KOG1339 Aspartyl protease
Length = 389
Score = 58.9 bits (141), Expect = 2e-08
Identities = 85/391 (21%), Positives = 154/391 (38%), Gaps = 85/391 (21%)
Query: 35 LKPADRSLQKRSKSFESKL-NPQDYFYTVELG---VGTPSQKINCIFDTGSSDLWVPAKS 90
L+ DR + RS + + + + DY Y +G VGTP Q + DTGS++L +P
Sbjct: 43 LEYRDRMVASRSSNLATVVQSTTDYVYYEYMGNITVGTPDQNFIVVLDTGSANLLIP--- 99
Query: 91 NPFCLGNKLDTNGTNEFHGTEITPILDCDKIGVFDPGSSYSLSATGYNFSTQYFDGSYSD 150
GT T C+K +F+ +S + AT + +Y G +
Sbjct: 100 ------------------GTNCTTY--CEKKRLFNEKASSTYIATNRPWQIKYASGD-AY 138
Query: 151 GFWVVDDISI-----ADQQVPDLQFAVANIS------SAPSGVLGVGLPRLEAVRGYDGA 199
G +D + I A +P VA+ S G+ G+ L
Sbjct: 139 GTLGIDTVKIGGSGEAQLAIPRSYLGVADTVGSDFKWSPKEGIFGLAFTALAVDNITPPI 198
Query: 200 PNANYDNFPQTLKSNRLINRVLYSLYFDS----GDLESGTVLFGGIDEKKYDGVLYTLPL 255
NA + L+++ L++ +F G SG +GG+D K + G P+
Sbjct: 199 INA---------INQGLLDQPLFTTWFGQRGAPGTSASGAFTYGGLD-KNHCG-----PV 243
Query: 256 VNIYEQIDEPAAFDITLQGLGIRSESNCKDTVIAHKKAPALLDSGSTIMGAPQEALESIA 315
+ Y ++ F G + S ++ + D+ ++ + PQ A++++A
Sbjct: 244 IG-YAELTNARHFQFQATGFSLGS-------YVSTTTYEVITDTATSFLCGPQAAIDNLA 295
Query: 316 QELGAAFSESDGLYVLDCPASNDDRTFYFDFGELKLKVPIHDLL-----YLPESGQNYCG 370
+ GA + ++ ++ + C A D G +K+K+ + + Y+ + N C
Sbjct: 296 KAAGATWDPTNQVFNIPCDA---------DAGPIKMKIGQFNYVIRANNYILKIDTNSCL 346
Query: 371 LAIIAS-----GEEWILGDLVLKSAYVVYDL 396
A I G WILG ++ V+D+
Sbjct: 347 FAAIPQNYAGFGPSWILGGPFMRQYCNVHDI 377
>Hs19923395 [O] KOG1339 Aspartyl protease
Length = 518
Score = 58.5 bits (140), Expect = 2e-08
Identities = 79/380 (20%), Positives = 151/380 (38%), Gaps = 77/380 (20%)
Query: 60 YTVELGVGTPSQKINCIFDTGSSDLWVPAKSNPFCLGNKLDTNGTNEFHGTEITPILDCD 119
Y +E+ +GTP QK+ + DTGSS+ V + + +DT
Sbjct: 92 YYLEMLIGTPPQKLQILVDTGSSNFAVAGTPHSY-----IDT------------------ 128
Query: 120 KIGVFDPGSSYSLSATGYNFSTQYFDGSYSDGFWVVDDISIADQQVPDLQFAVANISSAP 179
FD S + + G++ + +Y GS++ GF D ++I +A I +
Sbjct: 129 ---YFDTERSSTYRSKGFDVTVKYTQGSWT-GFVGEDLVTIPKGFNTSFLVNIATIFESE 184
Query: 180 ---------SGVLGVGLPRLEAVRGYDGAPNANYDNFPQTLKSNRLINRVLYSLYFDSG- 229
+G+LG+ L P+++ + F +L + I V +G
Sbjct: 185 NFFLPGIKWNGILGLAYATL-------AKPSSSLETFFDSLVTQANIPNVFSMQMCGAGL 237
Query: 230 -----DLESGTVLFGGIDEKKYDGVLYTLPLVNIYEQIDEPAAFDITLQGLGIRSESNCK 284
G+++ GGI+ Y G ++ P+ + E +I Q L + +C+
Sbjct: 238 PVAGSGTNGGSLVLGGIEPSLYKGDIWYTPIKEEWYYQIEILKLEIGGQSLNL----DCR 293
Query: 285 DTVIAHKKAPALLDSGSTIMGAPQEALESIAQELGAAF---SESDGLYV---LDCPASND 338
+ + A++DSG+T++ PQ+ +++ + + A SDG + L C +++
Sbjct: 294 E----YNADKAIVDSGTTLLRLPQKVFDAVVEAVARASLIPEFSDGFWTGSQLACWTNSE 349
Query: 339 DRTFYF---------DFGELKLKVPIHDLLYLPE---SGQNY--CGLAIIASGEEWILGD 384
YF + ++ I LY+ +G NY I S ++G
Sbjct: 350 TPWSYFPKISIYLRDENSSRSFRITILPQLYIQPMMGAGLNYECYRFGISPSTNALVIGA 409
Query: 385 LVLKSAYVVYDLDNLEISIA 404
V++ YV++D + A
Sbjct: 410 TVMEGFYVIFDRAQKRVGFA 429
>At1g05840 [O] KOG1339 Aspartyl protease
Length = 485
Score = 53.9 bits (128), Expect = 6e-07
Identities = 93/403 (23%), Positives = 159/403 (39%), Gaps = 65/403 (16%)
Query: 60 YTVELGVGTPSQKINCIFDTGSSDLWVPAKSNPFC-----LGNKLDTNGTNEFHGTEITP 114
Y ++G+GTP++ DTGS +WV C LG +L +E ++
Sbjct: 80 YYAKIGIGTPAKSYYVQVDTGSDIMWVNCIQCKQCPRRSTLGIELTLYNIDE---SDSGK 136
Query: 115 ILDCDKIGVFDPGSSYSLSATGYNFSTQYF----DGSYSDGFWVVDDISIADQQVPDLQF 170
++ CD + S LS N S Y DGS + G++V D + D DL+
Sbjct: 137 LVSCDDDFCYQI-SGGPLSGCKANMSCPYLEIYGDGSSTAGYFVKDVVQY-DSVAGDLKT 194
Query: 171 AVANISSAPSGVLGVGLPRL--------EAVRGYDGAPNANYDNFPQTLKSNRLINRVLY 222
AN S + G G + EA+ G G AN Q S R+ +
Sbjct: 195 QTAN----GSVIFGCGARQSGDLDSSNEEALDGILGFGKANSSMISQLASSGRVKKIFAH 250
Query: 223 SLYFDSGDLESGTVLFGGIDEKKYDGVLYTLPLVNIYEQIDEPAAFDITLQGLGIRSE-- 280
L +G G G + + P VN+ + +++ + + + E
Sbjct: 251 CLDGRNG---GGIFAIGRVVQ----------PKVNMTPLVPNQPHYNVNMTAVQVGQEFL 297
Query: 281 SNCKDTVIAHKKAPALLDSGSTIMGAPQEALESIAQELGAAFSESDGLYVLD-------- 332
+ D + A++DSG+T+ P+ E + +++ + + ++++D
Sbjct: 298 TIPADLFQPGDRKGAIIDSGTTLAYLPEIIYEPLVKKITSQ-EPALKVHIVDKDYKCFQY 356
Query: 333 ---CPASNDDRTFYFDFGELKLKVPIHDLLYLPESGQNYCGLAIIASGEE-----WILGD 384
+ TF+F+ + L+V HD L+ P G G A +LGD
Sbjct: 357 SGRVDEGFPNVTFHFE-NSVFLRVYPHDYLF-PHEGMWCIGWQNSAMQSRDRRNMTLLGD 414
Query: 385 LVLKSAYVVYDLDNLEISIAQVKTTSGSRIQ-----TVSATGS 422
LVL + V+YDL+N I + +S +++ TV GS
Sbjct: 415 LVLSNKLVLYDLENQLIGWTEYNCSSSIKVKDEGTGTVHLVGS 457
>At1g09750 [O] KOG1339 Aspartyl protease
Length = 387
Score = 53.5 bits (127), Expect = 7e-07
Identities = 67/272 (24%), Positives = 106/272 (38%), Gaps = 42/272 (15%)
Query: 60 YTVELGVGTPSQKINCIFDTGSSDLWVPAKSNPFC--LGNKLDTNGTNEFHGTEITPILD 117
Y V +GTP Q + + DT + +W+P C +TN ++ + +
Sbjct: 104 YVVRAKLGTPPQLMFMVLDTSNDAVWLPCSGCSGCSNASTSFNTNSSSTYSTVSCSTAQC 163
Query: 118 CDKIGVFDPGSSYSLSATGYNFSTQYFDGSYSDGFWVVDDISIADQQVPDLQFAVANISS 177
G+ P SS S +N S Y S V D +++A +P+ F N +S
Sbjct: 164 TQARGLTCPSSSPQPSVCSFNQS--YGGDSSFSASLVQDTLTLAPDVIPNFSFGCINSAS 221
Query: 178 A----PSGVLGVGLPRLEAVRG----YDGAPNANYDNFPQTLKSNRLINRVLYSLYFDSG 229
P G++G+G + V Y G F L S R S YF
Sbjct: 222 GNSLPPQGLMGLGRGPMSLVSQTTSLYSGV-------FSYCLPSFR-------SFYF--- 264
Query: 230 DLESGTVLFGGIDEKKYDGVLYTLPLVNIYEQIDEPAAFDITLQGLGIRSESNCKDTVI- 288
SG++ G + + K + YT PL+ P+ + + L G+ + S D V
Sbjct: 265 ---SGSLKLGLLGQPK--SIRYT-PLL---RNPRRPSLYYVNLTGVSVGSVQVPVDPVYL 315
Query: 289 ---AHKKAPALLDSGSTIMGAPQEALESIAQE 317
A+ A ++DSG+ I Q E+I E
Sbjct: 316 TFDANSGAGTIIDSGTVITRFAQPVYEAIRDE 347
>Hs21040362 [O] KOG1339 Aspartyl protease
Length = 396
Score = 53.1 bits (126), Expect = 1e-06
Identities = 65/306 (21%), Positives = 125/306 (40%), Gaps = 63/306 (20%)
Query: 60 YTVELGVGTPSQKINCIFDTGSSDLWVPAKSNPFCLGNKLDTNGTNEFHGTEITPILDCD 119
Y +E+ +GTP QK+ + DTGSS+ V + + +DT
Sbjct: 92 YYLEMLIGTPPQKLQILVDTGSSNFAVAGTPHSY-----IDT------------------ 128
Query: 120 KIGVFDPGSSYSLSATGYNFSTQYFDGSYSDGFWVVDDISIADQQVPDLQFAVANISSAP 179
FD S + + G++ + +Y GS++ GF D ++I +A I +
Sbjct: 129 ---YFDTERSSTYRSKGFDVTVKYTQGSWT-GFVGEDLVTIPKGFNTSFLVNIATIFESE 184
Query: 180 ---------SGVLGVGLPRLEAVRGYDGAPNANYDNFPQTLKSNRLINRVLYSLYFDSG- 229
+G+LG+ L P+++ + F +L + I V +G
Sbjct: 185 NFFLPGIKWNGILGLAYATL-------AKPSSSLETFFDSLVTQANIPNVFSMQMCGAGL 237
Query: 230 -----DLESGTVLFGGIDEKKYDGVLYTLPLVNIYEQIDEPAAFDITLQGLGIRSESNCK 284
G+++ GGI+ Y G ++ P+ + E +I Q L + +C+
Sbjct: 238 PVAGSGTNGGSLVLGGIEPSLYKGDIWYTPIKEEWYYQIEILKLEIGGQSLNL----DCR 293
Query: 285 DTVIAHKKAPALLDSGSTIMGAPQEALESIAQELGAAF---SESDGLYV---LDCPASND 338
+ + A++DSG+T++ PQ+ +++ + + A SDG + L C +++
Sbjct: 294 E----YNADKAIVDSGTTLLRLPQKVFDAVVEAVARASLIPEFSDGFWTGSQLACWTNSE 349
Query: 339 DRTFYF 344
YF
Sbjct: 350 TPWSYF 355
>At3g50050 [O] KOG1339 Aspartyl protease
Length = 632
Score = 52.8 bits (125), Expect = 1e-06
Identities = 80/368 (21%), Positives = 137/368 (36%), Gaps = 55/368 (14%)
Query: 59 FYTVELGVGTPSQKINCIFDTGSSDLWVPAKSNPFCLGNKLDTNGTNEFHGT--EITPIL 116
+YT L +GTP Q I D+GS+ +VP C G D E T + +
Sbjct: 92 YYTTRLWIGTPPQMFALIVDSGSTVTYVPCSDCEQC-GKHQDPKFQPEMSSTYQPVKCNM 150
Query: 117 DCDKIGVFDPGSSYSLSATGYNFSTQYFDGSYSDGFWVVDDISIADQQVPDLQFAVANIS 176
DC+ D + + +Y + S S G D IS ++ Q AV
Sbjct: 151 DCN----CDDDREQCV------YEREYAEHSSSKGVLGEDLISFGNESQLTPQRAVFGCE 200
Query: 177 SAPSGVLGVGLPRLEAVRGYDGAPNANYDNFPQTLKSNRLINRVLYSLYFDSGDLESGTV 236
+ +G L + G G + Q + + N + L + D+ G++
Sbjct: 201 TVETGDL-----YSQRADGIIGLGQGDLSLVDQLVDKGLISNS--FGLCYGGMDVGGGSM 253
Query: 237 LFGGIDEKKYDGVLYTLPLVNIYEQIDEPAAFDITLQGLGIRSESNCKDTVIAHKKAPAL 296
+ GG D Y +V D ++I L G+ + + + + + A+
Sbjct: 254 ILGGFD--------YPSDMVFTDSDPDRSPYYNIDLTGIRVAGKQLSLHSRVFDGEHGAV 305
Query: 297 LDSGSTIMGAPQEALESIAQELGAAFSESDGLYVLDCPASNDDRTFY------------- 343
LDSG+T P A + + A E L +D P N T +
Sbjct: 306 LDSGTTYAYLPDAAFAAFEE---AVMREVSTLKQIDGPDPNFKDTCFQVAASNYVSELSK 362
Query: 344 --------FDFGELKLKVPIHDLLYLPESGQNYCGLAIIASGEE--WILGDLVLKSAYVV 393
F G+ L P + + + YC L + +G++ +LG +V+++ VV
Sbjct: 363 IFPSVEMVFKSGQSWLLSPENYMFRHSKVHGAYC-LGVFPNGKDHTTLLGGIVVRNTLVV 421
Query: 394 YDLDNLEI 401
YD +N ++
Sbjct: 422 YDRENSKV 429
>Hs21040360 [O] KOG1339 Aspartyl protease
Length = 468
Score = 52.4 bits (124), Expect = 2e-06
Identities = 58/277 (20%), Positives = 114/277 (40%), Gaps = 57/277 (20%)
Query: 60 YTVELGVGTPSQKINCIFDTGSSDLWVPAKSNPFCLGNKLDTNGTNEFHGTEITPILDCD 119
Y +E+ +GTP QK+ + DTGSS+ V + + +DT
Sbjct: 92 YYLEMLIGTPPQKLQILVDTGSSNFAVAGTPHSY-----IDT------------------ 128
Query: 120 KIGVFDPGSSYSLSATGYNFSTQYFDGSYSDGFWVVDDISIADQQVPDLQFAVANISSAP 179
FD S + + G++ + +Y GS++ GF D ++I +A I +
Sbjct: 129 ---YFDTERSSTYRSKGFDVTVKYTQGSWT-GFVGEDLVTIPKGFNTSFLVNIATIFESE 184
Query: 180 ---------SGVLGVGLPRLEAVRGYDGAPNANYDNFPQTLKSNRLINRVLYSLYFDSG- 229
+G+LG+ L P+++ + F +L + I V +G
Sbjct: 185 NFFLPGIKWNGILGLAYATL-------AKPSSSLETFFDSLVTQANIPNVFSMQMCGAGL 237
Query: 230 -----DLESGTVLFGGIDEKKYDGVLYTLPLVNIYEQIDEPAAFDITLQGLGIRSESNCK 284
G+++ GGI+ Y G ++ P+ + E +I Q L + +C+
Sbjct: 238 PVAGSGTNGGSLVLGGIEPSLYKGDIWYTPIKEEWYYQIEILKLEIGGQSLNL----DCR 293
Query: 285 DTVIAHKKAPALLDSGSTIMGAPQEALESIAQELGAA 321
+ + A++DSG+T++ PQ+ +++ + + A
Sbjct: 294 E----YNADKAIVDSGTTLLRLPQKVFDAVVEAVARA 326
>CE09541 [O] KOG1339 Aspartyl protease
Length = 350
Score = 51.2 bits (121), Expect = 4e-06
Identities = 32/124 (25%), Positives = 55/124 (43%), Gaps = 19/124 (15%)
Query: 291 KKAPALLDSGSTIMGAPQEALESIAQELGAAFSESDGLYVLDCPASNDDRTFYFDFGELK 350
K + D+G++ +G P + IA++ GA + YV+DC A+ G L+
Sbjct: 228 KVVDVISDTGTSFLGGPSVVINEIAKQAGATYYILGEAYVIDCDATP---------GPLE 278
Query: 351 LKVPIHDLL-----YLPESGQNYCGLAII-----ASGEEWILGDLVLKSAYVVYDLDNLE 400
+ + HD Y+ + G C +A+ G WILGD ++ +YD+ N
Sbjct: 279 VTIGGHDYQIEHYNYIADVGDGTCVMALFPMDFGGFGPSWILGDPFIRQYCNIYDIGNFR 338
Query: 401 ISIA 404
+ A
Sbjct: 339 MGFA 342
>At2g36670 [O] KOG1339 Aspartyl protease
Length = 469
Score = 51.2 bits (121), Expect = 4e-06
Identities = 90/399 (22%), Positives = 153/399 (37%), Gaps = 75/399 (18%)
Query: 60 YTVELGVGTPSQKINCIFDTGSSDLWVPAKSNPFCLGNKLDTNGTN-EFHGTEITPILDC 118
Y ++ +G+P + N DTGS LWV S C ++G + H + L
Sbjct: 100 YFTKVKLGSPPTEFNVQIDTGSDILWVTCSSCSNCP----HSSGLGIDLHFFDAPGSLTA 155
Query: 119 DKIGVFDPGSSYSLSAT----------GYNFSTQYFDGSYSDGFWVVD---------DIS 159
+ DP S T GY+F +Y DGS + G+++ D +
Sbjct: 156 GSVTCSDPICSSVFQTTAAQCSENNQCGYSF--RYGDGSGTSGYYMTDTFYFDAILGESL 213
Query: 160 IADQQVPDLQFAVANISS--------APSGVLGVGLPRLEAVRGYDGAPNANYDNFPQTL 211
+A+ P + F + S A G+ G G +L V +
Sbjct: 214 VANSSAP-IVFGCSTYQSGDLTKSDKAVDGIFGFGKGKLSVV----------------SQ 256
Query: 212 KSNRLINRVLYSLYFDSGDLESGTVLFGGIDEKKYDGVLYTLPLVNIYEQIDEPAAFDIT 271
S+R I ++S + GD G V G E G++Y+ PLV +++
Sbjct: 257 LSSRGITPPVFS-HCLKGDGSGGGVFVLG--EILVPGMVYS-PLV------PSQPHYNLN 306
Query: 272 LQGLGIRSESNCKDTVI--AHKKAPALLDSGSTIMGAPQEALE--------SIAQELGAA 321
L +G+ + D + A ++D+G+T+ +EA + S++Q +
Sbjct: 307 LLSIGVNGQMLPLDAAVFEASNTRGTIVDTGTTLTYLVKEAYDLFLNAISNSVSQLVTPI 366
Query: 322 FSESDGLYVLDCPASNDDRTFYFDF-GELKLKVPIHDLLY---LPESGQNYCGLAIIASG 377
S + Y++ S+ + +F G + + D L+ + + +C A
Sbjct: 367 ISNGEQCYLVSTSISDMFPSVSLNFAGGASMMLRPQDYLFHYGIYDGASMWCIGFQKAPE 426
Query: 378 EEWILGDLVLKSAYVVYDLDNLEISIAQVKTTSGSRIQT 416
E+ ILGDLVLK VYDL I A R+ +
Sbjct: 427 EQTILGDLVLKDKVFVYDLARQRIGWASYDCKCNHRVMS 465
Database: KOG eukaryal database 04/03
Posted date: Apr 14, 2003 1:07 PM
Number of letters in database: 30,389,216
Number of sequences in database: 60,738
Lambda K H
0.316 0.136 0.398
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 30,416,314
Number of Sequences: 60738
Number of extensions: 1384941
Number of successful extensions: 3124
Number of sequences better than 1.0e-05: 58
Number of HSP's better than 0.0 without gapping: 5
Number of HSP's successfully gapped in prelim test: 53
Number of HSP's that attempted gapping in prelim test: 2971
Number of HSP's gapped (non-prelim): 72
length of query: 511
length of database: 30,389,216
effective HSP length: 111
effective length of query: 400
effective length of database: 23,647,298
effective search space: 9458919200
effective search space used: 9458919200
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.6 bits)