ORF STATUS Function Best COG Functional category Pathways and functional systems
r_klactIV3967 good C KOG1158 Energy production and conversion NADP/FAD dependent oxidoreductase
Only best alignment is shown:
BLASTP 2.2.3 [May-13-2002]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= r_klactIV3967 1343315 1346419 1035
(1035 letters)
Database: KOG eukaryal database 04/03
60,738 sequences; 30,389,216 total letters
Searching..................................................done
Color Key for Alignment Scores: 
Score E
Sequences producing significant alignments: (bits) Value
YFR030w [C] KOG1158 NADP/FAD dependent oxidoreductase 1254 0.0
SPCC584.01c [C] KOG1158 NADP/FAD dependent oxidoreductase 488 e-137
7297099 [C] KOG1158 NADP/FAD dependent oxidoreductase 179 3e-44
Hs22049499 [C] KOG1158 NADP/FAD dependent oxidoreductase 176 2e-43
At4g24520 [C] KOG1158 NADP/FAD dependent oxidoreductase 171 5e-42
At3g02280 [C] KOG1159 NADP-dependent flavoprotein reductase 170 9e-42
CE02018 [C] KOG1158 NADP/FAD dependent oxidoreductase 167 1e-40
Hs7657393 [C] KOG1159 NADP-dependent flavoprotein reductase 155 2e-37
At4g30210 [C] KOG1158 NADP/FAD dependent oxidoreductase 152 3e-36
Hs4505279 [C] KOG1158 NADP/FAD dependent oxidoreductase 149 2e-35
Hs13325068 [C] KOG1158 NADP/FAD dependent oxidoreductase 149 2e-35
7295098 [C] KOG1159 NADP-dependent flavoprotein reductase 142 2e-33
7297764 [C] KOG1158 NADP/FAD dependent oxidoreductase 138 4e-32
Hs20127412 [C] KOG1158 NADP/FAD dependent oxidoreductase 125 4e-28
CE23279 [C] KOG1159 NADP-dependent flavoprotein reductase 122 2e-27
Hs10835173_2 [C] KOG1158 NADP/FAD dependent oxidoreductase 122 4e-27
SPBC365.17 [C] KOG1158 NADP/FAD dependent oxidoreductase 120 1e-26
YHR042w [C] KOG1158 NADP/FAD dependent oxidoreductase 111 5e-24
Hs10835161 [C] KOG1158 NADP/FAD dependent oxidoreductase 110 9e-24
SPAC1296.06 [C] KOG1159 NADP-dependent flavoprotein reductase 105 4e-22
CE00868 [C] KOG1158 NADP/FAD dependent oxidoreductase 93 2e-18
SPBC12C2.03c [C] KOG1158 NADP/FAD dependent oxidoreductase 88 8e-17
YPR048w [C] KOG1159 NADP-dependent flavoprotein reductase 79 4e-14
SPAC1783.01 [C] KOG1158 NADP/FAD dependent oxidoreductase 74 2e-12
At1g20020 [C] KOG1158 NADP/FAD dependent oxidoreductase 72 4e-12
At5g66190 [C] KOG1158 NADP/FAD dependent oxidoreductase 72 6e-12
ECU05g0240 [C] KOG1159 NADP-dependent flavoprotein reductase 64 1e-09
At1g30510 [C] KOG1158 NADP/FAD dependent oxidoreductase 62 5e-09
At4g05390 [C] KOG1158 NADP/FAD dependent oxidoreductase 60 1e-08
>YFR030w [C] KOG1158 NADP/FAD dependent oxidoreductase
Length = 1035
Score = 1254 bits (3246), Expect = 0.0
Identities = 638/1044 (61%), Positives = 790/1044 (75%), Gaps = 18/1044 (1%)
Query: 1 MSLSYVTNPFGLPTESTQLPTFTTPVNAINSVLFRNLKSIFSYKTFSDPDLLDASIKKLA 60
M + + TNPFG +T LP + TPV AI+SVLF N+ SIF+YK+FS PDLL +KK +
Sbjct: 1 MPVEFATNPFGEAKNATSLPKYGTPVTAISSVLFNNVDSIFAYKSFSQPDLLHQDLKKWS 60
Query: 61 ERENGL-----FFKELDVRSGAGLTTLGFAKGSSDLAGIITPGYALPYFVSSFKQEIDTQ 115
E+ FF+ELD+RSGAGL LGF+ G + I+ PG++LPYF++S K +
Sbjct: 61 EKRGNESRGKPFFQELDIRSGAGLAPLGFSHGLKNTTAIVAPGFSLPYFINSLKT-VSHD 119
Query: 116 SKFVFSVGSLDYDEASGSIINDYLTPLKAAKDLGFPVITPLQISEVKXXXXXXXXXXKYG 175
KF+ +VG+L+YD A+GS+ NDY+T L AA L + V+TP+ +EV+ +
Sbjct: 120 GKFLLNVGALNYDNATGSVTNDYVTALDAASKLKYGVVTPISANEVQSVALLALAIATFS 179
Query: 176 SGLGAVQLFDGAQYARTVTRVEDKMQDRFIE---SLNLADDSTFDQILDAFNENSPERLH 232
+ GA+ LFDG Y++TV + + + + I S +A D+ FD +LD FNE + RLH
Sbjct: 180 NNSGAINLFDGLNYSKTVLPLVESVPEASILAKLSKVIAPDAAFDDVLDKFNELTGLRLH 239
Query: 233 NFQYYGNESAETIFITYGSLETELFASLLNQSGSKVGVLAVRIPLPFDTEKFVSLIPTTV 292
NFQY+G + AET+FITYGSLE+ELF S ++ + SK+G++ VR+PLPF+ KFV+ +P+T
Sbjct: 240 NFQYFGAQDAETVFITYGSLESELFNSAISGNNSKIGLINVRVPLPFNVAKFVTHVPSTT 299
Query: 293 KKIVVIGQSLTGQSPSWLRSQVSGALFFHNKRTLTIAEYIYQPNFVWSPKAVKQIVTSFI 352
K+IVVIGQ+L G SPS+LRSQVS ALF+H + +++++EYIYQP+F+WSPKAVK IV+SFI
Sbjct: 300 KQIVVIGQTLDGSSPSFLRSQVSAALFYHGRTSISVSEYIYQPDFIWSPKAVKSIVSSFI 359
Query: 353 PSFELEISSN-SQNFIYWTTDNSNNLDLAARLVQGLSLIDNVDISLRTKFDNIGNAGTFQ 411
P F S+ + FIYW +D S N+D+A++LV+ LSL D +SLRTKFDN+ NAGTFQ
Sbjct: 360 PEFTYNADSSFGEGFIYWASDKSINIDVASKLVKALSLEDGKFVSLRTKFDNLANAGTFQ 419
Query: 412 AQFTSHPSKSKSVVSNIDSADVIVVEDISILNAYDVASTVKQEGSIIXXXXXXXXXXXXX 471
AQF + SK + VSNIDS + VVED+S+L DVA+TV ++GSI
Sbjct: 420 AQFVT--SKEQIPVSNIDSTKLSVVEDVSLLKHLDVAATVAEQGSIALVSQKAVKDLDLN 477
Query: 472 XXXFYTDELKINEAFLTTVAEKKINVTLIDVETIGDREETKGRTLSFVTQAVFWSAATND 531
Y L I E+FL ++A+K I + +ID ET D + LS QAVFW A
Sbjct: 478 SVESYVKNLGIPESFLISIAKKNIKLFIIDGETTNDESK-----LSLFIQAVFWKLAFGL 532
Query: 532 DKQSIIRRIWNSAGPDIELLAAVLSDTISTALETGVKAIPNEVYATFIEDKAKGEEVKEE 591
D RIW S ++ AA +S+ ++ A + + +P +Y F E + +E EE
Sbjct: 533 DVAECTNRIWKSIDSGADISAASISEFLTGAFKNFLSEVPLALYTKFSEINIEKKE-DEE 591
Query: 592 EIHQLPTFVTETSFSANQRFTEEVPETEIAKIAEISKKLTFQEAYGVSQQLRPDLPVNNY 651
E LP FV ETSF N EE+P E ++I++I+KKL+F+EAY V +LRPDLPV N+
Sbjct: 592 EPAALPIFVNETSFLPNNSTIEEIPLPETSEISDIAKKLSFKEAYEVENKLRPDLPVKNF 651
Query: 652 VVKVKENRRVTPDDYDRYIFHIEFDISGTGMTYDIGEALGVHAKNNLENVQKFLQYYGLN 711
VVKVKENRRVTP DYDRYIFHIEFDISGTGMTYDIGEALG+HA+NN V++FL +YGLN
Sbjct: 652 VVKVKENRRVTPADYDRYIFHIEFDISGTGMTYDIGEALGIHARNNESLVKEFLTFYGLN 711
Query: 712 ESDIVQVPNKDDHHYLESRTVLQAFVENLDIFGKPPKRFYESLIDFCTDDKEKSKLENLV 771
ESD+V VPNKD+HH LE+RTVLQAFVENLDIFGKPPKRFYESLI + ++++EK KLE+LV
Sbjct: 712 ESDVVLVPNKDNHHLLETRTVLQAFVENLDIFGKPPKRFYESLIPYASNEEEKKKLEDLV 771
Query: 772 SAAGATELKRLQDVEYYTYADIFELFPSARPSVEDLVKIIAPLKRREYSIASSQRIHPNE 831
+ AGA +LKR QDVEYYTYADIFELFPS RPS+E+LV II PLKRREYSIASSQ++HPNE
Sbjct: 772 TPAGAVDLKRFQDVEYYTYADIFELFPSVRPSLEELVTIIEPLKRREYSIASSQKVHPNE 831
Query: 832 VHLLIVVVDWIDNKGRKRYGQASKFISDLAIGSELVVSVKPSVMKLPPSPKQPVIMSGLG 891
VHLLIVVVDW+DNKGRKRYGQASK+ISDLA+GSELVVSVKPSVMKLPPSPKQPVIMSGLG
Sbjct: 832 VHLLIVVVDWVDNKGRKRYGQASKYISDLAVGSELVVSVKPSVMKLPPSPKQPVIMSGLG 891
Query: 892 TGLAPFKAIVEEKLWQRQQGYEIGEVYLYLGSRHKREEYLYGELWEAYKDAGIITHIGAA 951
TGLAPFKAIVEEKLWQ+QQGYEIGEV+LYLGSRHKREEYLYGELWEAYKDAGIITHIGAA
Sbjct: 892 TGLAPFKAIVEEKLWQKQQGYEIGEVFLYLGSRHKREEYLYGELWEAYKDAGIITHIGAA 951
Query: 952 FSRDQPEKIYIQDRIKENLPELKTAMIDNEGSFYLCGPTWPVPDITQALQDIIAADAKEK 1011
FSRDQP+KIYIQDRIKENL ELKTAMIDN+GSFYLCGPTWPVPDITQALQDI+A DA+E+
Sbjct: 952 FSRDQPQKIYIQDRIKENLDELKTAMIDNKGSFYLCGPTWPVPDITQALQDILAKDAEER 1011
Query: 1012 GINVDLDAAIEDLKETSRYILEVY 1035
GI VDLDAAIE+LKE SRYILEVY
Sbjct: 1012 GIKVDLDAAIEELKEASRYILEVY 1035
>SPCC584.01c [C] KOG1158 NADP/FAD dependent oxidoreductase
Length = 1006
Score = 488 bits (1255), Expect = e-137
Identities = 297/812 (36%), Positives = 452/812 (55%), Gaps = 52/812 (6%)
Query: 235 QYYGNESAETIFITYGSLETELFASLLNQSGSKVGVLAVRIPLPFDTEKFVSLIPTTVKK 294
+YYG+++A + +T+G ET +LL + VGVL++RI PF E +++PTT K
Sbjct: 236 EYYGSQTASKVIVTFGKSETVAARALL-AANPDVGVLSIRI-FPFVAENIFNVLPTTCKS 293
Query: 295 IVVIGQ--SLTGQSPSWLRSQVSGALFFHNKRTLTIAEYIYQPNFVWSPKAVKQIVTSFI 352
+VV+ Q S + S S + L L I+E+ Y + + + +
Sbjct: 294 LVVLSQVRSTAVGTSSIYYSFLLATLLSTKPSALAISEHRYS---LVESVTLSSLFDALH 350
Query: 353 PSFELEISSNS-----QNFIYWTTDNSNNLDLAARLVQGLSLIDNVDISLRTKFDNIGNA 407
+ +L+ ++ ++ W +D ++L L+ LV + ++ R FDN+ A
Sbjct: 351 ETLQLKAATPKAVHVDKSINVWESDVGDSLVLS--LVSAYRTDKSRSVAFRPLFDNLTLA 408
Query: 408 GT--FQAQFTSHPSKSKSVVSNIDSADVIVVEDISILNAYDVASTVKQEGSIIXXXXXXX 465
G AQ ++ + VV ++D+ I+ D L+ +A + ++
Sbjct: 409 GVRFTVAQVSTANAVLTDVVKDVDADITILTTDRLPLHYRVLAKAAEHSICLLQSSIAPD 468
Query: 466 XXXXXXXXXFYTDELKINEAFLTTVAEKKINVTLIDVETIGDREETKGRTLSFVTQAVFW 525
F D L EK + + LID + +SF
Sbjct: 469 EATKKLPYEFIADAL-----------EKGVKLVLIDPKKFAIDASNLPLLVSF------- 510
Query: 526 SAATNDDKQSIIRRIWNSAGPDIELLAAVLSDTIS-TALETGVKAIPNEVYATFIEDKAK 584
I+ + G D L + ++ T L+ V ++ + +FI A
Sbjct: 511 -----------IQLVKPGLGVDEALAVLAKQNNLTDTNLKDAVDSLKQSL--SFINLDAS 557
Query: 585 GEEVKEEEIHQLPTFVTETSFSANQRFT-EEVPETEIAKIAEISKKLTFQEAYGVSQQLR 643
+ +E +LP+ ETSF+ N T +E + + ++K++ F EAY LR
Sbjct: 558 ALKDREPSEKELPSTAKETSFAPNAVKTLDEDITPQSSNWQTVAKQIIFPEAYKKKDALR 617
Query: 644 PDLPVNNYVVKVKENRRVTPDDYDRYIFHIEFDISGTGMTYDIGEALGVHAKNNLENVQK 703
PD+ + V V+ N+R+TP +Y+R IFHIEFD+ +G+TYDIGEALGV+ NN +V
Sbjct: 618 PDVSEKVFTVHVRANKRLTPAEYNRNIFHIEFDLGDSGLTYDIGEALGVYGVNNKTHVHD 677
Query: 704 FLQYYGLNESDIVQVPNKDDHHYLESRTVLQAFVENLDIFGKPPKRFYESLIDFCTDDKE 763
F++ YGL+ ++++ VP+ + E+RTV QA +N+DIFGKP K+F+E L++F TD+KE
Sbjct: 678 FIEEYGLDANELIHVPSIQHPGHWETRTVFQALCQNIDIFGKPTKKFHEQLLEFETDEKE 737
Query: 764 KSKLENLVSAAGATELKRLQDVEYYTYADIFELFPSARPSVEDLVKIIAPLKRREYSIAS 823
++ L+ L+S AGA + KR +V+ TYAD+ + F A+ + + +I+ +KRREYSI+S
Sbjct: 738 RADLQILISPAGAPDFKRRAEVDMLTYADVLKEFKHAKLTAAQIAQIVPVIKRREYSISS 797
Query: 824 SQRIHPNEVHLLIVVVDWIDNKGRKRYGQASKFISDLAIGSELVVSVKPSVMKLPPSPKQ 883
SQ+ H + VHLL+VVV W D GR RYGQ S ++S+L +G L V+VK SVMKLP SP +
Sbjct: 798 SQKKHNDSVHLLVVVVGWKDGMGRDRYGQCSHYLSNLKVGEPLCVAVKTSVMKLPTSPLK 857
Query: 884 PVIMSGLGTGLAPFKAIVEEKLWQRQQGYEIGEVYLYLGSRHKREEYLYGELWEAYKDAG 943
P++M+GLGTGLAPF+A ++ K WQR QG E G++ LYLGSR +REEYLYGE WEAY A
Sbjct: 858 PIVMAGLGTGLAPFRAFLQFKEWQRMQGIESGDILLYLGSRTQREEYLYGEDWEAYHSAN 917
Query: 944 IITHIGAAFSRDQPEKIYIQDRIKENLPELKTAMIDNEGSFYLCGPTWPVPDITQALQDI 1003
++THIG AFSRDQP KIYIQD ++ LK A++D GSFYLCGPTWP+P+IT L+++
Sbjct: 918 LLTHIGQAFSRDQPYKIYIQDVMRSTKDMLKKALMDEGGSFYLCGPTWPLPEITSVLEEV 977
Query: 1004 IAADAKEKGINVDLDAAIEDLKETSRYILEVY 1035
I + E VD IE KE R+++EVY
Sbjct: 978 IQSSYDEP---VDARKIIEQWKEERRFVIEVY 1006
>7297099 [C] KOG1158 NADP/FAD dependent oxidoreductase
Length = 679
Score = 179 bits (453), Expect = 3e-44
Identities = 122/411 (29%), Positives = 208/411 (49%), Gaps = 21/411 (5%)
Query: 640 QQLRPDLPVNN-YVVKVKENRRVTPDDYDRYIFHIEFDISGTGMTYDIGEALGVHAKNNL 698
Q RP N ++ +K NR + R HIE I G+ M YD G+ + + N+
Sbjct: 274 QNQRPPFDAKNPFLAPIKVNRELHKGG-GRSCMHIELSIEGSKMRYDAGDHVAMFPVNDK 332
Query: 699 ENVQKFLQYYGLNESDIVQVPNKDD-----HHYLESRTVLQAFVENLDIFGKPPKRFYES 753
V+K Q + + + N D H + T A L+I P +
Sbjct: 333 SLVEKLGQLCNADLDTVFSLINTDTDSSKKHPFPCPTTYRTALTHYLEITAIPRTHILKE 392
Query: 754 LIDFCTDDKEKSKLENLVSAAGATELKR---LQDVEYYTYADIFELFPSARPSVEDLVKI 810
L ++CTD+KEK L ++ S + + K +QD I E S RP ++ + ++
Sbjct: 393 LAEYCTDEKEKELLRSMASISPEGKEKYQSWIQDA-CRNIVHILEDIKSCRPPIDHVCEL 451
Query: 811 IAPLKRREYSIASSQRIHPNEVHLLIVVVDWIDNKGRKRYGQASKFISDLAI-GSELV-- 867
+ L+ R YSI+SS ++HP +VH+ V+V++ GR G A+ ++ + GSE V
Sbjct: 452 LPRLQPRYYSISSSAKLHPTDVHVTAVLVEYKTPTGRINKGVATTYLKNKQPQGSEEVKV 511
Query: 868 -VSVKPSVMKLPPSPKQPVIMSGLGTGLAPFKAIVEEKLWQRQQGYEIGEVYLYLGSRHK 926
V ++ S +LP P+ P+IM G GTGLAPF+ ++E+ + R +G +GE LY G R +
Sbjct: 512 PVFIRKSQFRLPTKPETPIIMVGPGTGLAPFRGFIQERQFLRDEGKTVGESILYFGCRKR 571
Query: 927 REEYLYGELWEAYKDAGIITHIGAAFSRDQPEKIYIQDRIKENLPELKTAMIDNEGSFYL 986
E+Y+Y E + G + ++ AAFSRDQ +K+Y+Q ++++ + + +N+G FY+
Sbjct: 572 SEDYIYESELEEWVKKGTL-NLKAAFSRDQGKKVYVQHLLEQDADLIWNVIGENKGHFYI 630
Query: 987 CGPTWPVPDITQALQDIIAADAKEKGINVDLDAA--IEDLKETSRYILEVY 1035
CG ++ +++I+ KG + DA I+ ++ RY +V+
Sbjct: 631 CG---DAKNMAVDVRNILVKILSTKGNMSEADAVQYIKKMEAQKRYSADVW 678
>Hs22049499 [C] KOG1158 NADP/FAD dependent oxidoreductase
Length = 653
Score = 176 bits (445), Expect = 2e-43
Identities = 121/403 (30%), Positives = 199/403 (49%), Gaps = 22/403 (5%)
Query: 649 NNYVVKVKENRRVTPDDYDRYIFHIEFDISGTGMTYDIGEALGVHAKNNLENVQKFLQYY 708
N ++ V NR++ +R++ H+E DIS + + Y+ G+ + V+ N+ V + +
Sbjct: 256 NPFLAAVTTNRKLNQGT-ERHLMHLELDISDSKIRYESGDHVAVYPANDSALVNQLGKIL 314
Query: 709 GLNESDIVQVPNKDD-----HHYLESRTVLQAFVENLDIFGKPPKRFYESLIDFCTDDKE 763
G + ++ + N D+ H + + A LDI P L + ++ E
Sbjct: 315 GADLDVVMSLNNLDEESNKKHPFPCPTSYRTALTYYLDITNPPRTNVLYELAQYASEPSE 374
Query: 764 KSKLENLVSAAGATE---LKRLQDVEYYTYADIFELFPSARPSVEDLVKIIAPLKRREYS 820
+ L + S++G + L + + + A I + PS RP ++ L +++ L+ R YS
Sbjct: 375 QELLRKMASSSGEGKELYLSWVVEARRHILA-ILQDCPSLRPPIDHLCELLPRLQARYYS 433
Query: 821 IASSQRIHPNEVHLLIVVVDWIDNKGRKRYGQASKFISDLAIGSE------LVVSVKPSV 874
IASS ++HPN VH+ VVV++ GR G A+ ++ E + + V+ S
Sbjct: 434 IASSSKVHPNSVHICAVVVEYETKAGRINKGVATNWLRAKEPAGENGGRALVPMFVRKSQ 493
Query: 875 MKLPPSPKQPVIMSGLGTGLAPFKAIVEEKLWQRQQGYEIGEVYLYLGSRHKREEYLYGE 934
+LP PVIM G GTG+APF ++E+ W RQQG E+GE LY G R E+YLY E
Sbjct: 494 FRLPFKATTPVIMVGPGTGVAPFIGFIQERAWLRQQGKEVGETLLYYGCRRSDEDYLYRE 553
Query: 935 LWEAYKDAGIITHIGAAFSRDQPEKIYIQDRIKENLPELKTAMIDNEGSFYLCGPTWPVP 994
+ G +T + AFSR+Q K+Y+Q +K++ L +I+ Y+CG +
Sbjct: 554 ELAQFHRDGALTQLNVAFSREQSHKVYVQHLLKQDREHL-WKLIEGGAHIYVCGDARNMA 612
Query: 995 -DITQALQDIIA-ADAKEKGINVDLDAAIEDLKETSRYILEVY 1035
D+ DI+A A E VD I+ L RY L+V+
Sbjct: 613 RDVQNTFYDIVAELGAMEHAQAVDY---IKKLMTKGRYSLDVW 652
>At4g24520 [C] KOG1158 NADP/FAD dependent oxidoreductase
Length = 692
Score = 171 bits (433), Expect = 5e-42
Identities = 114/402 (28%), Positives = 208/402 (51%), Gaps = 23/402 (5%)
Query: 653 VKVKENRRVTPDDYDRYIFHIEFDISGTGMTYDIGEALGVHAKNNLENVQKFLQYYGLNE 712
V V + + + DR H+EFDIS TG+TY+ G+ +GV+A+N++E V++ + G +
Sbjct: 295 VDVAVQKELHTHESDRSCIHLEFDISRTGITYETGDHVGVYAENHVEIVEEAGKLLGHSL 354
Query: 713 SDIVQV-PNKDDHHYLESR---------TVLQAFVENLDIFGKPPKRFYESLIDFCTDDK 762
+ + +K+D LES T+ D+ P K +L + T+
Sbjct: 355 DLVFSIHADKEDGSPLESAVPPPFPGPCTLGTGLARYADLLNPPRKSALVALAAYATEPS 414
Query: 763 EKSKLENLVSAAGATELKRLQDVEYYTYADIFELFPSARPSVEDLVKIIAP-LKRREYSI 821
E KL++L S G E + + ++ FPSA+P + IAP L+ R YSI
Sbjct: 415 EAEKLKHLTSPDGKDEYSQWIVASQRSLLEVMAAFPSAKPPLGVFFAAIAPRLQPRYYSI 474
Query: 822 ASSQRIHPNEVHLLIVVVDWIDNKGRKRYGQASKFISDLAIG------SELVVSVKPSVM 875
+SS R+ P+ VH+ +V GR G S ++ + S + ++ S
Sbjct: 475 SSSPRLAPSRVHVTSALVYGPTPTGRIHKGVCSTWMKNAVPAEKSHECSGAPIFIRASNF 534
Query: 876 KLPPSPKQPVIMSGLGTGLAPFKAIVEEKLWQRQQGYEIGEVYLYLGSRHKREEYLYGEL 935
KLP +P P++M G GTGLAPF+ ++E++ ++ G E+G L+ G R+++ +++Y +
Sbjct: 535 KLPSNPSTPIVMVGPGTGLAPFRGFLQERMALKEDGEELGSSLLFFGCRNRQMDFIYEDE 594
Query: 936 WEAYKDAGIITHIGAAFSRDQPEKIYIQDRIKENLPELKTAMIDNEGSFYLCGPTWPVP- 994
+ D G+I+ + AFSR+ +K Y+Q ++ E ++ +I EG Y+CG +
Sbjct: 595 LNNFVDQGVISELIMAFSREGAQKEYVQHKMMEKAAQV-WDLIKEEGYLYVCGDAKGMAR 653
Query: 995 DITQALQDIIAADAKEKGI-NVDLDAAIEDLKETSRYILEVY 1035
D+ + L I+ +++G+ + + +A ++ L+ RY+ +V+
Sbjct: 654 DVHRTLHTIV---QEQEGVSSSEAEAIVKKLQTEGRYLRDVW 692
>At3g02280 [C] KOG1159 NADP-dependent flavoprotein reductase
Length = 616
Score = 170 bits (431), Expect = 9e-42
Identities = 118/421 (28%), Positives = 211/421 (50%), Gaps = 21/421 (4%)
Query: 633 QEAYGVSQ-QLRPDLPVNNYVVKVKENRRVTPDDYDRYIFHIEFDISGTGMTYDIGEALG 691
Q A G+S +L D + +K+ N +T + + + H EF + + Y++G+ +
Sbjct: 198 QRARGMSPGKLFKDKSKPDCFLKMTRNEVLTKAESTKDVRHFEFQFVSSTIEYEVGDVVE 257
Query: 692 VHAKNNLENVQKFLQYYGLNESDIVQV-PNKDDHHYLESRTV------LQAFVE-NLDIF 743
+ N V F++ GL+ + V P + ++ + L+ FVE +D+
Sbjct: 258 LLPSQNSSVVDAFIERCGLDPESFITVGPRETENSSFSEEMITQIPIKLKTFVELTMDVT 317
Query: 744 GKPPKRFYESLIDF-CTDDKEKSKLENLVSAAGATELKRLQDVEYYTYADIFELFPSARP 802
P+R++ ++ F T + EK +L+ S G +L E + ++ E FPS +
Sbjct: 318 SASPRRYFFEIMSFYATAEHEKERLQYFASPEGRDDLYNYNQKERRSILEVLEDFPSVQI 377
Query: 803 SVEDLVKIIAPLKRREYSIASSQRIHPNEVHLLIVVVDWIDNKGRKRYGQASKFISDLAI 862
+ LV+++ PLK R +SI+SS HP VHL + +V WI R R G S +++ LA
Sbjct: 378 PFDWLVQLVPPLKPRAFSISSSPLAHPAAVHLTVSIVSWITPYKRTRKGLCSSWLASLAP 437
Query: 863 GSELVVSVKPSVMKLP-PSPKQPVIMSGLGTGLAPFKAIVEEKLWQRQQGYEIGEVYLYL 921
E+ + V LP PS P+I+ G GTG APF+ + E+ Q Q + V +
Sbjct: 438 EQEVNIPVWFHKGSLPAPSQSLPLILVGPGTGCAPFRGFIAERAVQAQSS-PVAPVMFFF 496
Query: 922 GSRHKREEYLYGELWEAY-KDAGIITH-----IGAAFSRDQPEKIYIQDRIKENLPELKT 975
G R+K ++LY + WE++ ++ G+++ AFSRDQP+K+Y+Q +I+E +
Sbjct: 497 GCRNKDTDFLYRDFWESHAREGGMLSEGKGGGFYTAFSRDQPKKVYVQHKIREMSKRVWD 556
Query: 976 AMIDNEGSFYLCGPTWPVP-DITQALQDIIAADAKEKGINVDLDAAIEDLKETSRYILEV 1034
+ D + Y+ G + +P D+ A +DI++ + G ++ L++T RY +E
Sbjct: 557 LLCDG-AAVYVAGSSTKMPCDVMSAFEDIVSEET-GGGSKEVASRWLKALEKTGRYNVEA 614
Query: 1035 Y 1035
+
Sbjct: 615 W 615
>CE02018 [C] KOG1158 NADP/FAD dependent oxidoreductase
Length = 662
Score = 167 bits (422), Expect = 1e-40
Identities = 118/410 (28%), Positives = 201/410 (48%), Gaps = 17/410 (4%)
Query: 637 GVSQQLRPDLPVNN-YVVKVKENRRVTPDDYDRYIFHIEFDISGTGMTYDIGEALGVHAK 695
G ++ RP V N Y+ V N + + DR HIEF + G+ + Y+ G+ L V
Sbjct: 258 GAYERPRPPFDVKNPYLATVAINDELHTEHSDRSCRHIEFSVEGSRIRYEAGDHLAVFPT 317
Query: 696 NNLENVQKFLQYYGLNESDIVQVPNKDD-----HHYLESRTVLQAFVENLDIFGKPPKRF 750
N+ V + + + ++ N D+ H + T A +DI
Sbjct: 318 NDPVLVDRLINMLQFDPDHAFRLVNVDEDASKRHPFPCPTTFRTALSHYVDICAPVKSHV 377
Query: 751 YESLIDFCTDDKEKSKLENLVSA--AGATELKRLQDVEYYTYADIFELFPSARPSVEDLV 808
+++ ++CTDD EK L L +A G E R E + D+ + +P +E L+
Sbjct: 378 LKAISEYCTDDTEKEFLNKLSTANEEGLKEYARYIVKERRSIVDVLTDQKTCKPPIEYLL 437
Query: 809 KIIAPLKRREYSIASSQRIHPNEVHLLIVVVDWIDNKGRKRYGQASKFISDLAIGSELVV 868
+++ L+ R YSIASS R++ ++ + VV + R G +++++ GS+ V
Sbjct: 438 ELLPRLQARYYSIASSPRLNEEKIAICAVVTKYSIGD-RDINGVCTRYLTTKDAGSKSPV 496
Query: 869 SVKPSVMKLPPSPKQPVIMSGLGTGLAPFKAIVEEKLWQRQQGYEIGEVYLYLGSRHKRE 928
V+ S M+LP VIM G GTG APF+ ++++ + + G EIG ++LY G RH
Sbjct: 497 FVRKSTMRLPHRTTTQVIMIGPGTGFAPFRGFLQDRQFHKNAGKEIGAMHLYYGCRHPDH 556
Query: 929 EYLYGELWEAYKDAGIITHIGAAFSRDQPEKIYIQDRIKENLPELKTAMIDNEGSFYLCG 988
+Y+Y + +++ ++TH+ AFSR Q KIY+QDR+ E + A I+ Y+CG
Sbjct: 557 DYIYKDELAKFQEDEVLTHLVCAFSRAQEHKIYVQDRLWETRDRIWDA-INVGAHVYICG 615
Query: 989 PTWPVP-DITQALQDIIAADAKEKGINVDLDAA--IEDLKETSRYILEVY 1035
+ D+ LQ I +E G + +A +D+++T RY +V+
Sbjct: 616 DARNMARDVQATLQKIF----REIGGKSETEAVAYFKDMEKTKRYQADVW 661
>Hs7657393 [C] KOG1159 NADP-dependent flavoprotein reductase
Length = 597
Score = 155 bits (393), Expect = 2e-37
Identities = 116/398 (29%), Positives = 205/398 (51%), Gaps = 23/398 (5%)
Query: 651 YVVKVKENRRVTPDDYDRYIFHIEFDISGTGMTYDIGEALGVHAKNNLENVQKFLQYYGL 710
++ + N+RVT + + + IEFDI G+G+++ G+ + + N+ +VQ+F Q GL
Sbjct: 209 FLAPMISNQRVTGPSHFQDVRLIEFDILGSGISFAAGDVVLIQPSNSAAHVQRFCQVLGL 268
Query: 711 NESDIVQV----PNKDDHHYLESRTVLQAFVEN-LDIFGKPPKRFYESLIDFCTDDKEKS 765
+ + + P+ L ++ V + LDI P + F+E L + E+
Sbjct: 269 DPDQLFMLQPREPDVSSPTRLPQPCSMRHLVSHYLDIASVPRRSFFELLACLSLHELERE 328
Query: 766 KLENLVSAAGATELKRLQDVEYYTYADIFELFPSARPSV--EDLVKIIAPLKRREYSIAS 823
KL SA G EL + T ++ FP ++ + L+ +I ++ R +SIAS
Sbjct: 329 KLLEFSSAQGQEELFEYCNRPRRTILEVLCDFPHTAAAIPPDYLLDLIPVIRPRAFSIAS 388
Query: 824 SQRIHPNEVHLLIVVVDWIDNKGRKRYGQASKFISDLAIGSELV---VSVKPSVMKLPPS 880
S HP+ + +L+ VV + R G S +++ L G V + V+P + P +
Sbjct: 389 SLLTHPSRLQILVAVVQFQTRLKEPRRGLCSSWLASLDPGQGPVRVPLWVRPGSLAFPET 448
Query: 881 PKQPVIMSGLGTGLAPFKAIVEEKLWQRQQGYEIGEVYLYLGSRHKREEYLYGELWEAYK 940
P PVIM G GTG+APF+A ++E++ Q Q G +L+ G R + +++ + W+ +
Sbjct: 449 PDTPVIMVGPGTGVAPFRAAIQERVAQGQTGN-----FLFFGCRWRDQDFYWEAEWQELE 503
Query: 941 DAGIITHIGAAFSRDQPEKIYIQDRIKENLPELKTAMIDNEGS-FYLCGPTWPVP-DITQ 998
+T I AFSR+Q +K+Y+Q R++E L L ++D +G+ FYL G +P D+++
Sbjct: 504 KRDCLTLI-PAFSREQEQKVYVQHRLRE-LGSLVWELLDRQGAYFYLAGNAKSMPADVSE 561
Query: 999 ALQDIIAADAKEKGI-NVDLDAAIEDLKETSRYILEVY 1035
AL I +E G+ + D A + L++T R+ E +
Sbjct: 562 ALMSIF---QEEGGLCSPDAAAYLARLQQTRRFQTETW 596
>At4g30210 [C] KOG1158 NADP/FAD dependent oxidoreductase
Length = 711
Score = 152 bits (383), Expect = 3e-36
Identities = 110/404 (27%), Positives = 194/404 (47%), Gaps = 24/404 (5%)
Query: 651 YVVKVKENRRVTPDDYDRYIFHIEFDISGTGMTYDIGEALGVHAKNNLENVQKFLQYYGL 710
Y V R + + DR H+EFDI+G+G+TY+ G+ +GV N E V + L+ +
Sbjct: 313 YKANVAVKRELHTPESDRSCIHLEFDIAGSGLTYETGDHVGVLCDNLSETVDEALRLLDM 372
Query: 711 NESDIVQV-PNKDDHHYLESR--------TVLQAFVENLDIFGKPPKRFYESLIDFCTDD 761
+ + K+D + S + A + P K +L +D
Sbjct: 373 SPDTYFSLHAEKEDGTPISSSLPPPFPPCNLRTALTRYACLLSSPKKSALVALAAHASDP 432
Query: 762 KEKSKLENLVSAAGATELKRLQDVEYYTYADIFELFPSARPSVEDLVKIIAP-LKRREYS 820
E +L++L S AG E + + ++ FPSA+P + +AP L+ R YS
Sbjct: 433 TEAERLKHLASPAGKDEYSKWVVESQRSLLEVMAEFPSAKPPLGVFFAGVAPRLQPRFYS 492
Query: 821 IASSQRIHPNEVHLLIVVVDWIDNKGRKRYGQASKFISDLAIG------SELVVSVKPSV 874
I+SS +I +H+ +V GR G S ++ + S + V+ S
Sbjct: 493 ISSSPKIAETRIHVTCALVYEKMPTGRIHKGVCSTWMKNAVPYEKSENCSSAPIFVRQSN 552
Query: 875 MKLPPSPKQPVIMSGLGTGLAPFKAIVEEKLWQRQQGYEIGEVYLYLGSRHKREEYLYGE 934
KLP K P+IM G GTGLAPF+ ++E+L + G E+G L+ G R++R +++Y E
Sbjct: 553 FKLPSDSKVPIIMIGPGTGLAPFRGFLQERLALVESGVELGPSVLFFGCRNRRMDFIYEE 612
Query: 935 LWEAYKDAGIITHIGAAFSRDQPEKIYIQDRIKENLPELKTAMIDNEGSFYLCGPTWPVP 994
+ + ++G + + AFSR+ P K Y+Q ++ + ++ MI Y+CG +
Sbjct: 613 ELQRFVESGALAELSVAFSREGPTKEYVQHKMMDKASDIWN-MISQGAYLYVCGDAKGMA 671
Query: 995 -DITQALQDIIAADAKEKGI--NVDLDAAIEDLKETSRYILEVY 1035
D+ ++L I A+E+G + + +++L+ + RY+ +V+
Sbjct: 672 RDVHRSLHTI----AQEQGSMDSTKAEGFVKNLQTSGRYLRDVW 711
>Hs4505279 [C] KOG1158 NADP/FAD dependent oxidoreductase
Length = 698
Score = 149 bits (376), Expect = 2e-35
Identities = 117/428 (27%), Positives = 198/428 (45%), Gaps = 47/428 (10%)
Query: 651 YVVKVKENRRVTPDDYDRYIFHIEFDISGTGMTYDIGEALGVHAKNNLENVQKFLQYYGL 710
+ V + + ++T +D + +E DIS T +Y G+A V N+ VQ LQ L
Sbjct: 274 FQVPISKAVQLTTNDAIKTTLLVELDISNTDFSYQPGDAFSVICPNSDSEVQSLLQRLQL 333
Query: 711 NES--DIVQVPNKDD---------HHYLESRTVLQAFVENLDIFGKPPKRFYESLIDFCT 759
+ V + K D H ++ F L+I P K F +L+D+ +
Sbjct: 334 EDKREHCVLLKIKADTKKKGATLPQHIPAGCSLQFIFTWCLEIRAIPKKAFLRALVDYTS 393
Query: 760 DDKEKSKLENLVSAAGATELKRLQDVEYYTYADIFELFPSARPSVEDLVKIIAPLKRREY 819
D EK +L+ L S GA + R D+ FPS +P + L++ + L+ R Y
Sbjct: 394 DSAEKRRLQELCSKQGAADYSRFVRDACACLLDLLLAFPSCQPPLSLLLEHLPKLQPRPY 453
Query: 820 SIASSQRIHPNEVHLLIVVVDWIDNKGRK--RYGQASKFISDLAIGSEL----------- 866
S ASS HP ++H + +V+++ + R G + +++ L + S L
Sbjct: 454 SCASSSLFHPGKLHFVFNIVEFLSTATTEVLRKGVCTGWLA-LLVASVLQPNIHASHEDS 512
Query: 867 ------VVSVKP---SVMKLPPSPKQPVIMSGLGTGLAPFKAIVE--EKLWQRQQGYEIG 915
+S+ P + LP P P+IM G GTG+APF ++ EKL ++ G
Sbjct: 513 GKALAPKISISPRTTNSFHLPDDPSIPIIMVGPGTGIAPFIGFLQHREKLQEQHPDGNFG 572
Query: 916 EVYLYLGSRHKREEYLYGELWEAYKDAGIITHIGAAFSRDQP------EKIYIQDRIKEN 969
++L+ G RHK +YL+ + + GI+TH+ +FSRD P Y+QD I+ +
Sbjct: 573 AMWLFFGCRHKDRDYLFRKELRHFLKHGILTHLKVSFSRDAPVGEEEAPAKYVQDNIQLH 632
Query: 970 LPELKTAMIDNEGSFYLCGPTWPV-PDITQALQDIIAADAKEKGI-NVDLDAAIEDLKET 1027
++ ++ G Y+CG + D+ AL II +KE G+ ++ + LKE
Sbjct: 633 GQQVARILLQENGHIYVCGDAKNMAKDVHDALVQII---SKEVGVEKLEAMKTLATLKEE 689
Query: 1028 SRYILEVY 1035
RY+ +++
Sbjct: 690 KRYLQDIW 697
>Hs13325068 [C] KOG1158 NADP/FAD dependent oxidoreductase
Length = 725
Score = 149 bits (376), Expect = 2e-35
Identities = 117/428 (27%), Positives = 198/428 (45%), Gaps = 47/428 (10%)
Query: 651 YVVKVKENRRVTPDDYDRYIFHIEFDISGTGMTYDIGEALGVHAKNNLENVQKFLQYYGL 710
+ V + + ++T +D + +E DIS T +Y G+A V N+ VQ LQ L
Sbjct: 301 FQVPISKAVQLTTNDAIKTTLLVELDISNTDFSYQPGDAFSVICPNSDSEVQSLLQRLQL 360
Query: 711 NES--DIVQVPNKDD---------HHYLESRTVLQAFVENLDIFGKPPKRFYESLIDFCT 759
+ V + K D H ++ F L+I P K F +L+D+ +
Sbjct: 361 EDKREHCVLLKIKADTKKKGATLPQHIPAGCSLQFIFTWCLEIRAIPKKAFLRALVDYTS 420
Query: 760 DDKEKSKLENLVSAAGATELKRLQDVEYYTYADIFELFPSARPSVEDLVKIIAPLKRREY 819
D EK +L+ L S GA + R D+ FPS +P + L++ + L+ R Y
Sbjct: 421 DSAEKRRLQELCSKQGAADYSRFVRDACACLLDLLLAFPSCQPPLSLLLEHLPKLQPRPY 480
Query: 820 SIASSQRIHPNEVHLLIVVVDWIDNKGRK--RYGQASKFISDLAIGSEL----------- 866
S ASS HP ++H + +V+++ + R G + +++ L + S L
Sbjct: 481 SCASSSLFHPGKLHFVFNIVEFLSTATTEVLRKGVCTGWLA-LLVASVLQPNIHASHEDS 539
Query: 867 ------VVSVKP---SVMKLPPSPKQPVIMSGLGTGLAPFKAIVE--EKLWQRQQGYEIG 915
+S+ P + LP P P+IM G GTG+APF ++ EKL ++ G
Sbjct: 540 GKALAPKISISPRTTNSFHLPDDPSIPIIMVGPGTGIAPFIGFLQHREKLQEQHPDGNFG 599
Query: 916 EVYLYLGSRHKREEYLYGELWEAYKDAGIITHIGAAFSRDQP------EKIYIQDRIKEN 969
++L+ G RHK +YL+ + + GI+TH+ +FSRD P Y+QD I+ +
Sbjct: 600 AMWLFFGCRHKDRDYLFRKELRHFLKHGILTHLKVSFSRDAPVGEEEAPAKYVQDNIQLH 659
Query: 970 LPELKTAMIDNEGSFYLCGPTWPV-PDITQALQDIIAADAKEKGI-NVDLDAAIEDLKET 1027
++ ++ G Y+CG + D+ AL II +KE G+ ++ + LKE
Sbjct: 660 GQQVARILLQENGHIYVCGDAKNMAKDVHDALVQII---SKEVGVEKLEAMKTLATLKEE 716
Query: 1028 SRYILEVY 1035
RY+ +++
Sbjct: 717 KRYLQDIW 724
>7295098 [C] KOG1159 NADP-dependent flavoprotein reductase
Length = 582
Score = 142 bits (359), Expect = 2e-33
Identities = 107/368 (29%), Positives = 183/368 (49%), Gaps = 16/368 (4%)
Query: 654 KVKENRRVTPDDYDRYIFHIEFDISGTGMTYDIGEALGVHAKNNLENVQKF---LQYYGL 710
K+ +N+R T D+ + + + ++++ G+ L V +N+ E VQ F ++ + L
Sbjct: 200 KILDNQRTTAVDHFQDVRFLRLQCQTEDLSWEPGDVLDVQPQNSDEAVQTFFDLIREHSL 259
Query: 711 N--ESDIVQVPNKDDHH-----YLESRTVLQAFVENLDIFGKPPKRFYESLIDFCTDDKE 763
N ES IV+V + Y ++LQA D+ KP +RF E L C D+ E
Sbjct: 260 NFDESTIVEVSSAHQDMPLPIAYSNPLSLLQAAKFVWDLSAKPRQRFLEVLAQNCCDEME 319
Query: 764 KSKLENLVSAAGATELKRLQDVEYYTYADIFELFPSARPSV--EDLVKIIAPLKRREYSI 821
K KL SA G +L + ++ E F A S+ + L +++ ++ R +SI
Sbjct: 320 KEKLLEFSSAEGIDDLVAYVNRPRRNLLEVLEDFRHATSSLTLQQLFEMMPLIQPRSFSI 379
Query: 822 ASSQRIHPNEVHLLIVVVDWIDNKGRKRYGQASKFISDLAIGSELVVSVKPSVMKLPPSP 881
AS + + LL+ VV++ R G S ++ L G+EL VK M P
Sbjct: 380 ASD--VSALSLDLLVAVVEYKTIMHTPRLGLCSNWLKTLKSGTELSGVVKRGTMVWPKDL 437
Query: 882 KQPVIMSGLGTGLAPFKAIVEEKLWQRQQGYEIGEVYLYLGSRHKREEYLYGELWEAYKD 941
P+IM G GTG+APF++I++ +L+ + +G IG + ++ G R+K ++ +G + + D
Sbjct: 438 SIPLIMVGPGTGIAPFRSIIQNRLYAQSKGATIGPLVVFFGCRNKAADFHFGNDFSTWTD 497
Query: 942 AGIITHIGAAFSRDQPEKIYIQDRIKENLPELKTAMIDNEGSFYLCGPTWPVP-DITQAL 1000
A + AFSRDQ +K+Y+Q I +N L + D Y+ G + +P + +A
Sbjct: 498 AKQV-EAHTAFSRDQDQKVYVQHLIAKNGAHLARLIKDLNAYIYVAGNSNNMPKSVKEAF 556
Query: 1001 QDIIAADA 1008
+I+ DA
Sbjct: 557 IEILDGDA 564
>7297764 [C] KOG1158 NADP/FAD dependent oxidoreductase
Length = 1349
Score = 138 bits (348), Expect = 4e-32
Identities = 106/381 (27%), Positives = 183/381 (47%), Gaps = 26/381 (6%)
Query: 676 DISGTGMTYDIGEALGVHAKNNLENVQKFL-QYYGLNESDIV---------QVPNK---- 721
+I G+ Y+ G+ +G+ N E V L + G++ D V Q N
Sbjct: 949 EICAPGLEYEPGDHVGIFPANRTELVDGLLNRLVGVDNPDEVLQLQLLKEKQTSNGIFKC 1008
Query: 722 -DDHHYLESRTVLQAFVENLDIFGKPPKRFYESLIDFCTDDKEKSKLENLVSAAGATELK 780
+ H + T+ D+ P ++ L FC D +K +LE LV+ + A E
Sbjct: 1009 WEPHDKIPPDTLRNLLARFFDLTTPPSRQLLTLLAGFCEDTADKERLELLVNDSSAYEDW 1068
Query: 781 RLQDVEYYTYADIFELFPSARPSVEDLVKIIAPLKRREYSIASSQRIHPNEVHLLIVVVD 840
R + + D+ E FPS RP L+ + PL+ R YSI+SS R +E+HL + +V
Sbjct: 1069 RHWRLPHLL--DVLEEFPSCRPPAPLLLAQLTPLQPRFYSISSSPRRVSDEIHLTVAIVK 1126
Query: 841 W--IDNKGRKRYGQASKFISDLAIGSELVVSVKPSV-MKLPPSPKQPVIMSGLGTGLAPF 897
+ D +G +RYG S ++S L EL + V+ ++ LP +P+I+ G GTG+APF
Sbjct: 1127 YRCEDGQGDERYGVCSNYLSGLRADDELFMFVRSALGFHLPSDRSRPIILIGPGTGIAPF 1186
Query: 898 KAIVEE--KLWQRQQGYEIGEVYLYLGSRHKREEYLYGELWEAYKDAGIITHIGAAFSRD 955
++ +E L ++ +++L+ G R++ + E E KD I+ + A SR+
Sbjct: 1187 RSFWQEFQVLSDLDPTAKLPKMWLFFGCRNRDVDLYAEEKAELQKDQ-ILDRVFLALSRE 1245
Query: 956 QP-EKIYIQDRIKENLPELKTAMIDNEGSFYLCGPTWPVPDITQALQDIIAADAKEKGIN 1014
Q K Y+QD I++ L ++ G Y+CG + Q ++ IA KE+
Sbjct: 1246 QAIPKTYVQDLIEQEFDSLYQLIVQERGHIYVCGDVTMAEHVYQTIRKCIA--GKEQKSE 1303
Query: 1015 VDLDAAIEDLKETSRYILEVY 1035
+++ + L++ SRY +++
Sbjct: 1304 AEVETFLLTLRDESRYHEDIF 1324
>Hs20127412 [C] KOG1158 NADP/FAD dependent oxidoreductase
Length = 1153
Score = 125 bits (313), Expect = 4e-28
Identities = 111/411 (27%), Positives = 183/411 (44%), Gaps = 37/411 (9%)
Query: 649 NNYVVKVKENRRVTPDDYDRYIFHIEFDIS-GTGMTYDIGEALGVHAKNNLENVQKFLQY 707
N + +++K + + R +E G G+ Y GE LGV N VQ L+
Sbjct: 731 NVFTMRLKSRQNLQSPTSSRATILVELSCEDGQGLNYLPGEHLGVCPGNQPALVQGILER 790
Query: 708 Y-------------GLNESDIVQVPNKDDHHYLESRTVLQAFVENLDIFGKPPKRFYESL 754
L+ES V +K L ++ QA LDI P + + L
Sbjct: 791 VVDGPTPHQTVRLEALDESGSYWVSDKR----LPPCSLSQALTYFLDITTPPTQLLLQKL 846
Query: 755 IDFCTDDKEKSKLENLVSAAGATELKRLQDVEYYTYADIFELFPSARPSVEDLVKIIAPL 814
T++ E+ +LE L + E + + T+ ++ E FPS R S L+ + L
Sbjct: 847 AQVATEEPERQRLEALCQPS---EYSKWKFTNSPTFLEVLEEFPSLRVSAGFLLSQLPIL 903
Query: 815 KRREYSIASSQRIHPNEVHLLIVVVDW--IDNKGRKRYGQASKFISDLAIGSELVVSVK- 871
K R YSI+SS+ P E+HL + VV + D +G +G S +++ L + V+
Sbjct: 904 KPRFYSISSSRDHTPTEIHLTVAVVTYHTRDGQGPLHHGVCSTWLNSLKPQDPVPCFVRN 963
Query: 872 PSVMKLPPSPKQPVIMSGLGTGLAPFKAIVEEKLWQRQ-QGYEIGEVYLYLGSRHKREEY 930
S LP P P I+ G GTG+APF++ +++L Q +G G + L G R E++
Sbjct: 964 ASGFHLPEDPSHPCILIGPGTGIAPFRSFWQQRLHDSQHKGVRGGRMTLVFGCRRPDEDH 1023
Query: 931 LYGELWEAYKDAGIITHIGAAFSR-DQPEKIYIQDRIKENL-PELKTAMIDNEGSFYLCG 988
+Y E G++ + A+SR K+Y+QD +++ L E+ + G Y+CG
Sbjct: 1024 IYQEEMLEMAQKGVLHAVHTAYSRLPGKPKVYVQDILRQQLASEVLRVLHKEPGHLYVCG 1083
Query: 989 PTWPVPDITQALQDIIAADAKEKGINVDLDAAIED----LKETSRYILEVY 1035
D+ L+ ++AA K + +ED LK RY +++
Sbjct: 1084 DVRMARDVAHTLKQLVAAKLKLN------EEQVEDYFFQLKSQKRYHEDIF 1128
>CE23279 [C] KOG1159 NADP-dependent flavoprotein reductase
Length = 585
Score = 122 bits (307), Expect = 2e-27
Identities = 112/414 (27%), Positives = 189/414 (45%), Gaps = 37/414 (8%)
Query: 619 EIAKIAEISKKLTFQEAYGVS--------QQLRPDLPVNNYV-VKVKENRRVTPDDYDRY 669
EI +I+ K F E G S + L P + + +Y +KV +NRR+T ++ +
Sbjct: 166 EIDTSVQITTKYRFLELGGESGNDDDDSDEDLEPQIEIPDYFPLKVLKNRRLTSAEHFQD 225
Query: 670 IFHIEFDISGTG---MTYDIGEALGVHAKNNLENVQKFLQYYGLNESDIVQ----VPN-- 720
++F+IS M + G+ L V N E V+ ++ GL E + + V N
Sbjct: 226 TRLVDFEISDRNRSKMGFQPGDVLMVRPYNPEETVKIAIEALGLTEEQLKKPLKIVKNDR 285
Query: 721 --KDDHHYL--ESRTVLQAFVENLDIFGKPPKRFYESLIDFCTDDKEKSKLENLVSAAGA 776
K+ ++L T+L D+ P + F+E L + T+ EK +L+ L S G
Sbjct: 286 FSKNPPNFLVGTKTTLLTCLQRYFDLQQVPKRSFFEMLGYYSTNPPEKERLQELASPEGL 345
Query: 777 TELKRLQDVEYYTYADIFELFPSARPSVED--LVKIIAPLKRREYSIASSQRIHPNEVHL 834
+ + T A+ F + +++ L +I+ ++ R +SIAS+ P + L
Sbjct: 346 DDYLDYANRSRRTTAEALRDFVATSKNLKPDYLFEILTTIRPRAFSIASAPS--PFHLEL 403
Query: 835 LIVVVDWIDNKGRKRYGQASKFISDLAIGSELVVSVKPSVMKLPPSPKQPVIMSGLGTGL 894
L+ V++ KR G S FIS L G E+ ++P K PSP+ PVI G GTG+
Sbjct: 404 LVAKVEYKSRMADKRRGLCSTFISRLKPGDEVFCKIRPGTFKF-PSPEAPVICIGPGTGV 462
Query: 895 APFKAIVEEKLWQRQQGYEIGEVYLYLGSRHKREEYLYGELWEAYKDAGIITHIGAAFSR 954
APF+++ + I L+ G R + +Y + + W +I AFSR
Sbjct: 463 APFRSLFGHRSLFSAHFPGI----LFFGCRSEHHDYYFSDEWPELSGVAVI----PAFSR 514
Query: 955 D-QPEKIYIQDRIKENLPELKTAMIDNEGSFYLCGPTWPVPDITQALQDIIAAD 1007
D K+Y+Q ++ EN ++K M+D ++ G + +P A+ I D
Sbjct: 515 DTDGRKVYVQHKMGENAGKIK-RMLDLGAQVFIAGSSGDMPKAVSAVLAQIQGD 567
>Hs10835173_2 [C] KOG1158 NADP/FAD dependent oxidoreductase
Length = 1157
Score = 122 bits (305), Expect = 4e-27
Identities = 96/327 (29%), Positives = 165/327 (50%), Gaps = 16/327 (4%)
Query: 718 VPNKDDHHYLESRTVLQAFVENLDIFGKPPKRFYESLIDFCTDDKEKSKLENLVSAAGAT 777
+ N D L T+ QAF LDI P + T +KEK +L LV + G
Sbjct: 804 ISNWTDELRLPPCTIFQAFKYYLDITTPPTPLQLQQFASLATSEKEKQRL--LVLSKGLQ 861
Query: 778 ELKRLQDVEYYTYADIFELFPSARPSVEDLVKIIAPLKRREYSIASSQRIHPNEVHLLIV 837
E + + + T ++ E FPS + L+ ++ L+ R YSI+SS ++P+EVHL +
Sbjct: 862 EYEEWKWGKNPTIVEVLEEFPSIQMPATLLLTQLSLLQPRYYSISSSPDMYPDEVHLTVA 921
Query: 838 VVDW--IDNKGRKRYGQASKFISDLAIGSELV---VSVKPSVMKLPPSPKQPVIMSGLGT 892
+V + D +G +G S +++ + ELV V PS LP +P+ P I+ G GT
Sbjct: 922 IVSYRTRDGEGPIHHGVCSSWLNRIQ-ADELVPCFVRGAPS-FHLPRNPQVPCILVGPGT 979
Query: 893 GLAPFKAIVEEKLWQRQ-QGYEIGEVYLYLGSRHKREEYLYGELWEAYKDAGIITHIGAA 951
G+APF++ +++ + Q +G + L G R + +++Y E K+ G+ + A
Sbjct: 980 GIAPFRSFWQQRQFDIQHKGMNPCPMVLVFGCRQSKIDHIYREETLQAKNKGVFRELYTA 1039
Query: 952 FSR--DQPEKIYIQDRIKENLPE-LKTAMIDNEGSFYLCGPTWPVPDITQALQDIIAADA 1008
+SR D+P+K Y+QD ++E L E + A+ + G Y+CG D+ +A+Q I+
Sbjct: 1040 YSREPDKPKK-YVQDILQEQLAESVYRALKEQGGHIYVCGDVTMAADVLKAIQRIMTQQG 1098
Query: 1009 KEKGINVDLDAAIEDLKETSRYILEVY 1035
K D I +++ +RY +++
Sbjct: 1099 KLSA--EDAGVFISRMRDDNRYHEDIF 1123
>SPBC365.17 [C] KOG1158 NADP/FAD dependent oxidoreductase
Length = 678
Score = 120 bits (301), Expect = 1e-26
Identities = 105/407 (25%), Positives = 181/407 (43%), Gaps = 52/407 (12%)
Query: 668 RYIFHIEFDISGTGMTYDIGEALGVHAKNNLENVQKFLQYYGLNESD-----IVQVPNKD 722
R H+E DI+ +GM Y G+ + N + V L+ GL E + + D
Sbjct: 285 RNCLHLELDIADSGMRYQTGDYASICPMNPSQAVDDLLEVLGLKEKRDTVIIVKPIDTLD 344
Query: 723 DHHYLESRTVLQAFVENLDIFGKPPKRFYESLIDFCTDDKEKSKLENLVSAAGATELKRL 782
L T F +I G ++ + F + K +LE L + + K +
Sbjct: 345 KAPVLSPTTYDTVFRYYYEICGIVSRQLLSFIAPFAPTPESKQELEKLGNDYDYFK-KNV 403
Query: 783 QDVEYYTYADIFELFPSA---RPSVEDLVKIIAPLKRREYSIASSQRIHPNEVHLLIVV- 838
D+ + + P A + L++ +A +K R YSI+SS +HP++VH+ VV
Sbjct: 404 VDLHLNLAQVLRRVSPDAPFTKLPFSMLLENMAHMKPRYYSISSSSVVHPDKVHVTAVVD 463
Query: 839 -VDWIDNKG--------------RKRYGQASKFISDLAIGSE---------LVVSVKPSV 874
+W D R +G+ + L E + + VK S
Sbjct: 464 KKEWTDKNHIFYGLTTNYLLAHCRHMHGEKIPHPNGLEYTLEGPRKNWTGKIPMFVKKST 523
Query: 875 MKLPPSPKQPVIMSGLGTGLAPFKAIVEEKLWQRQQGYEIGEVYLYLGSRHKREEYLYGE 934
+L P P P+IM G GTG+APF+ V E+ +G ++ + L+ G ++ +++LY E
Sbjct: 524 FRLAP-PDVPIIMVGPGTGVAPFRGFVMERANLASKGVKVAKTLLFYGCQYSDKDFLYKE 582
Query: 935 LWEAYKDA-----GIITHIGAAFSRDQPEKIYIQDRIKENLPELKTAMIDNEGSFYLCGP 989
W+ YKD +IT AFSR+Q KIY+Q R+ E+ + +++ +FY+CG
Sbjct: 583 EWQQYKDVLKDSFELIT----AFSREQDHKIYVQHRLLEHSDTI-AKLVEEGAAFYICGD 637
Query: 990 T-WPVPDITQALQDIIAADAKEKGINVDLDAAIEDLKETSRYILEVY 1035
D+ AL I+ ++VD A++ L++ +R+ + +
Sbjct: 638 ADHMAKDVVNALASILTT------VDVDGMKAVKALRDDNRFFEDTW 678
>YHR042w [C] KOG1158 NADP/FAD dependent oxidoreductase
Length = 691
Score = 111 bits (278), Expect = 5e-24
Identities = 125/502 (24%), Positives = 222/502 (43%), Gaps = 68/502 (13%)
Query: 587 EVKEEEIH---QLPTFVTETSFSANQRFTEEVPETEIAKIAEISKKLTFQEAYGVSQQLR 643
EV ++E+H Q F ++ ++ T+ + E + S +L + A G+ QL
Sbjct: 205 EVLKDELHLDEQEAKFTSQFQYTVLNEITDSMSLGEPSAHYLPSHQLN-RNADGI--QLG 261
Query: 644 PDLPVNNYVVKVKENRRVTPDDYDRYIFHIEFDISGTGMTYDIGEALGVHAKNNLENVQK 703
P Y+ + ++R + + DR H EFD+SG+ + Y G+ L V N LE V++
Sbjct: 262 PFDLSQPYIAPIVKSRELFSSN-DRNCIHSEFDLSGSNIKYSTGDHLAVWPSNPLEKVEQ 320
Query: 704 FLQYYGLNESDIVQVPNKDDH---HYLESRTVLQAFVENLDIFGKPPKRFYESLIDFC-- 758
FL + L+ I + D + T+ A L+I G ++ + SLI F
Sbjct: 321 FLSIFNLDPETIFDLKPLDPTVKVPFPTPTTIGAAIKHYLEITGPVSRQLFSSLIQFAPN 380
Query: 759 TDDKEKSKLENLVSAAGATELKRLQDVEYYTYADIFELFPSARP----SVEDLVKIIAPL 814
D KEK L + A E+ +Y+ AD + ++ LV+ + +
Sbjct: 381 ADVKEKLTLLSKDKDQFAVEITS----KYFNIADALKYLSDGAKWDTVPMQFLVESVPQM 436
Query: 815 KRREYSIASSQRIHPNEVHLLIVVVDWIDNK---GRKRYGQASKFISDLAIGS------- 864
R YSI+SS VH+ +V ++ + + G + + ++ +
Sbjct: 437 TPRYYSISSSSLSEKQTVHVTSIVENFPNPELPDAPPVVGVTTNLLRNIQLAQNNVNIAE 496
Query: 865 -------------------ELVVSVKPSVMKLPPSPKQPVIMSGLGTGLAPFKAIVEEK- 904
+L V V+ S +LP +P PVIM G GTG+APF+ + E+
Sbjct: 497 TNLPVHYDLNGPRKLFANYKLPVHVRRSNFRLPSNPSTPVIMIGPGTGVAPFRGFIRERV 556
Query: 905 --LWQRQQG---YEIGEVYLYLGSRHKREEYLYGELWEAY--KDAGIITHIGAAFSRDQP 957
L +++G +G+ L+ GSR+ +++LY + W Y K G + A
Sbjct: 557 AFLESQKKGGNNVSLGKHILFYGSRN-TDDFLYQDEWPEYAKKLDGSFEMVVAHSRLPNT 615
Query: 958 EKIYIQDRIKENLPELKTAMIDNEGSFYLCGPT-WPVPDITQALQDIIAADAKEKGINVD 1016
+K+Y+QD++K+ ++ MI+N Y+CG ++ AL I++ +G ++
Sbjct: 616 KKVYVQDKLKDYEDQV-FEMINNGAFIYVCGDAKGMAKGVSTALVGILS-----RGKSIT 669
Query: 1017 LDAA---IEDLKETSRYILEVY 1035
D A I+ LK + RY +V+
Sbjct: 670 TDEATELIKMLKTSGRYQEDVW 691
>Hs10835161 [C] KOG1158 NADP/FAD dependent oxidoreductase
Length = 1203
Score = 110 bits (276), Expect = 9e-24
Identities = 88/319 (27%), Positives = 156/319 (48%), Gaps = 26/319 (8%)
Query: 731 TVLQAFVENLDIFGKPPKRFYESLIDFCTDDKEKSKLENLVSAAGATELKRLQDVEYY-- 788
T+ QA LDI P + L + +E+ +LE L + + +R ++ +++
Sbjct: 854 TLRQALTFFLDITSPPSPQLLRLLSTLAEEPREQQELEAL-----SQDPRRYEEWKWFRC 908
Query: 789 -TYADIFELFPSARPSVEDLVKIIAPLKRREYSIASSQRIHPNEVHLLIVVVDWI--DNK 845
T ++ E FPS L+ + L+ R YS++S+ HP E+HL + V+ + D
Sbjct: 909 PTLLEVLEQFPSVALPAPLLLTQLPLLQPRYYSVSSAPSTHPGEIHLTVAVLAYRTQDGL 968
Query: 846 GRKRYGQASKFISDLAIGSELVVSVK--PSVMKLPPSPKQPVIMSGLGTGLAPFKAIVEE 903
G YG S ++S L G + ++ PS +LPP P P I+ G GTG+APF+ +E
Sbjct: 969 GPLHYGVCSTWLSQLKPGDPVPCFIRGAPS-FRLPPDPSLPCILVGPGTGIAPFRGFWQE 1027
Query: 904 KLWQ-RQQGYEIGEVYLYLGSRHKREEYLYGELWEAYKDAGIITHIGAAFSR--DQPEKI 960
+L +G + + L G R + ++LY + + + G+ + AFSR D P K
Sbjct: 1028 RLHDIESKGLQPTPMTLVFGCRCSQLDHLYRDEVQNAQQRGVFGRVLTAFSREPDNP-KT 1086
Query: 961 YIQDRIKENL-PELKTAMIDNEGSFYLCGPTWPVPDITQALQDIIAADAKEKGINVDLDA 1019
Y+QD ++ L E+ + G ++CG ++ Q +Q I+A + +++LD
Sbjct: 1087 YVQDILRTELAAEVHRVLCLERGHMFVCGDVTMATNVLQTVQRILATEG-----DMELDE 1141
Query: 1020 A---IEDLKETSRYILEVY 1035
A I L++ RY +++
Sbjct: 1142 AGDVIGVLRDQQRYHEDIF 1160
>SPAC1296.06 [C] KOG1159 NADP-dependent flavoprotein reductase
Length = 558
Score = 105 bits (262), Expect = 4e-22
Identities = 75/298 (25%), Positives = 143/298 (47%), Gaps = 11/298 (3%)
Query: 740 LDIFGKPPKRFYESLIDFCTDDKEKSKLENLVSAAGATELKRLQDVEYYTYADIFELFPS 799
L I P + F+E F + K +L+ S + T + + F S
Sbjct: 270 LSIHSVPSRTFFEMASHFSNNKMHKERLQEFSSYKNIDDYYDYTTRPRRTVLETLQEFKS 329
Query: 800 ARPSVEDLVKIIAPLKRREYSIASSQRIHPNEVHLLIVVVDWIDNKGRKRYGQASKFISD 859
+ +E + ++ R+YSIA+ + L + +V + R G S++I D
Sbjct: 330 VQIPIEYALDAFPVIRGRQYSIANRCDNSTGILELAVALVKYQTILKSPRQGICSRWICD 389
Query: 860 LAIGSELVVSVKPSVMKLPPSPKQPVIMSGLGTGLAPFKAIVEEKLWQRQQGYEIGEVYL 919
L + + + P + L +P+IM G GTG+AP +A+++E+++ + E L
Sbjct: 390 LHENTSFNIDILPGFLNLSYQSNKPLIMVGPGTGVAPLRALIQERIYN-----GLKENLL 444
Query: 920 YLGSRHKREEYLYGELWEAYKDAGIITHIGAAFSRDQPEKIYIQDRIKENLPELKTAMID 979
+ G R+K ++L+ + WE Y + G + + AFSRDQ +K Y+Q I+EN + + +
Sbjct: 445 FFGCRNKSMDFLFEKDWEKYTEEGTL-KLFCAFSRDQEKKKYVQHSIQENGELVYNLLNE 503
Query: 980 NEGSFYLCGPTWPVPDITQALQDIIAA-DAKEKGINV-DLDAAIEDLKETSRYILEVY 1035
+G F++ G + +P +++D IA +K G ++ D + + L++ +RY E +
Sbjct: 504 KDGMFFVSGSSGKMP---SSVKDAIAGIVSKYSGCSISDGYSFVTSLEKKNRYYQETW 558
>CE00868 [C] KOG1158 NADP/FAD dependent oxidoreductase
Length = 682
Score = 92.8 bits (229), Expect = 2e-18
Identities = 100/414 (24%), Positives = 184/414 (44%), Gaps = 55/414 (13%)
Query: 654 KVKENRRVTPDDYDRYIFHIEFDISGTGMTYDIGEALGVHAKNNLENVQKFLQYYGL--- 710
K+K R +T ++F + Y+ G+A+ N V L+ G+
Sbjct: 291 KIKTKRMIT----------VDFGDHAAELQYEPGDAIYFCVPNPALEVNFILKRCGVLDI 340
Query: 711 ------------NESDIVQVPNKDDHHYLESRTVLQAFVENLDIFGKPPKRFYESLIDFC 758
E Q+P H + T+ F LDI P + L +
Sbjct: 341 ADQQCELSINPKTEKINAQIPG----HVHKITTLRHMFTTCLDIRRAPGRPLIRVLAEST 396
Query: 759 TDDKEKSKLENLVSAAGATELKRLQDVEYYTYADIFELFPSARPSVEDLVKIIAPLKRRE 818
+D EK +L L SA G + + AD+ FP+ +P V+ L++++ L R
Sbjct: 397 SDPNEKRRLLELCSAQGMKDFTDFVRTPGLSLADMLFAFPNVKPPVDRLIELLPRLIPRP 456
Query: 819 YSIASSQRIHPNEVHLLIVVVDWIDNKGRK--RYGQASKFISDLAIGSEL-VVSVKPSVM 875
YS++S + + L+ +++ GR+ R G A+ +++ L IG ++ V+ +P+
Sbjct: 457 YSMSSYEN---RKARLIYSEMEFPATDGRRHSRKGLATDWLNSLRIGDKVQVLGKEPARF 513
Query: 876 KLPP-------SPKQPVIMSGLGTGLAPFKAIVE--EKLWQRQQG--YEIGEVYLYLGSR 924
+LPP + K P++M G GTG++ F + + KL Q ++ V L+ G R
Sbjct: 514 RLPPLGMTKNSAGKLPLLMVGPGTGVSVFLSFLHFLRKLKQDSPSDFVDVPRV-LFFGCR 572
Query: 925 HKREEYLYGELWEAYKDAGIITHIGAAFSRDQPEKIYIQDRIKENLPE-LKTAMIDNEGS 983
+ +Y E + GI+T + S + E+ +QD +++ L + L E
Sbjct: 573 DSSVDAIYMSELEMFVSEGILTDLIICESEQKGER--VQDGLRKYLDKVLPFLTASTESK 630
Query: 984 FYLCGPTWPV-PDITQALQDIIAADAKEKGI-NVDLDAAIEDLKETSRYILEVY 1035
++CG + D+ Q DI+A+D +GI +++ + DLK++ +YI +V+
Sbjct: 631 IFICGDAKGMSKDVWQCFSDIVASD---QGIPDLEAKKKLMDLKKSDQYIEDVW 681
>SPBC12C2.03c [C] KOG1158 NADP/FAD dependent oxidoreductase
Length = 571
Score = 87.8 bits (216), Expect = 8e-17
Identities = 101/449 (22%), Positives = 179/449 (39%), Gaps = 61/449 (13%)
Query: 642 LRPDLPVNNYVVKVKENRRVTPDDYDRYIFHIEFDISG----TGMTYDIGEALGVHAKNN 697
++P P + + + + R +T + +FH E D+S G + +G + GV A NN
Sbjct: 129 VQPHPPFSVFPAPILDVRELTKPGAVKRVFHFELDVSNYPLPEGEEWMVGGSFGVMAPNN 188
Query: 698 LENVQKFLQYYGLN--ESDIVQVPNKDDHHY-------------LESRTVLQAFVENLDI 742
E+V + LQ +N ++D + D + R +L+ VE + +
Sbjct: 189 EEDVDELLQLLHINPDQADAPVLLKTDGGRWPTIWAEDTPRELVTTRRELLKWTVEFMSV 248
Query: 743 FGKPPKRFYESLIDFCTDDKEKSKLENLVSAAGATELKRLQDVEYYTYADIFELFPSARP 802
P K+ L ++ DD E+ L LVS G L+D T + + FPS +
Sbjct: 249 --APKKQLIRLLAEYAKDDTERQVLLFLVSRLGQRAFCDLRD-HNVTLITLLKAFPSVQL 305
Query: 803 SVEDLVKIIAPLKRREYSIASSQRIHPNEVHLLIVVVDWIDNKGRKRYGQASKFISDLAI 862
++ L+ ++ L R YS+++ ++ N + + VV+ +G R G S F+ LA+
Sbjct: 306 PLDHLLTVLPQLMPRWYSLSNDPKVSNNVLEFAVTVVEINKVEGGTRSGIGSGFLKRLAL 365
Query: 863 -----GSELVVSVKPSVMK----LPPSPKQPVIMSGLGTGLAPFKAIVEEKLWQRQQGYE 913
+LV+ + + K + P+ + G G G+APF+ V+ +L
Sbjct: 366 RFLNGERDLVLPMYRGLHKNAFATHFASDGPMCLIGAGVGVAPFRGFVQRRLTNATCA-- 423
Query: 914 IGEVYLYLGSRHKREEYLYGELWE------AYKDAGIITHIGAAFSRDQPE--------- 958
G+V+++ G R + + LY WE + DA D E
Sbjct: 424 -GKVWVFHGCRDQELDELYHGEWENPLQKSSDDDASSTVSQQTETEMDSFEVKKDGTSGP 482
Query: 959 -----------KIYIQDRIKENLPELKTAMIDNEGSFYLCGPTWPVPD-ITQALQDIIAA 1006
Y+QD I+ + + + G YLCG D + AL D+
Sbjct: 483 NHLVVESRSHQHAYVQDEIRHRGDIVWSVLSHPHGKVYLCGGKKGFLDGVENALIDVCVQ 542
Query: 1007 DAKEKGINVDLDAAIEDLKETSRYILEVY 1035
K + A+ +YI E++
Sbjct: 543 YGKMSRLEATQQLALWQSPLNLKYIKEIW 571
>YPR048w [C] KOG1159 NADP-dependent flavoprotein reductase
Length = 623
Score = 79.0 bits (193), Expect = 4e-14
Identities = 90/410 (21%), Positives = 186/410 (44%), Gaps = 40/410 (9%)
Query: 652 VVKVKENRRVTPDDYDRYIFHIEF-DISGTGMTYDIGEALGVHAKNNLENVQKFL--QYY 708
V +V N+R+T + + + + +F ++ Y+ G+ + ++ N E+V +FL Q +
Sbjct: 228 VGRVNINKRITSEGHFQDVRQFKFSNVDKIQENYEPGDTVTIYPCNTDEDVSRFLANQSH 287
Query: 709 GLNESD-----IVQVPNK-DDHHYLESRTVLQAFVENLDIFGKPPKRFYESLIDFCTD-- 760
L +D VPN D + T+ + D P F+ + F TD
Sbjct: 288 WLEIADKPLNFTSGVPNDLKDGGLVRPMTLRNLLKYHCDFMSIPRTSFFLKIWTFATDVT 347
Query: 761 ---------DKEKSKLENLVSAAGATELKRLQDVEYYTYADIFELFPSARPSVEDLVKII 811
+ ++ KL + +L + + ++ E F S + + ++ +
Sbjct: 348 KMERGQEQLNDQREKLRQFATDQDMQDLYDYCNRPRRSILEVLEDFISVKLPWKYVLDYL 407
Query: 812 APLKRREYSIASSQRIHPNEVHLLIVVVDWIDNKGRKRYGQASKFISDLAIGSELVVSVK 871
+K R YSI+S PN + L + +V + + R G + +I+ L G ++ ++
Sbjct: 408 PIIKPRYYSISSGPG-DPN-IELTVAIVKYKTILRKIRRGICTNYIARLQEGEQIRYKLQ 465
Query: 872 PSVMKLPPSPKQPVIMSGLGTGLAPFKAIVEEKLWQRQQGYEIGEVYLYLGSRHKREEYL 931
+ + +P+I+ G G GLAP ++V+ ++ + ++ L G R+K ++Y+
Sbjct: 466 NNHIIKKEFLNKPMILVGPGVGLAPLLSVVKAEISK--------DIKLLFGCRYKDKDYI 517
Query: 932 YGELWEAYKDAGIITHIGAAFSRDQ---PEKIYIQDRIKENLPELKTAMIDNEGSFYLCG 988
Y ++ E + G I + ++FSRD+ P Y+QD + E+ +++ + F+LCG
Sbjct: 518 YKDMLEDWFRKGKIA-LHSSFSRDEENSPGVKYVQDYLWRLGEEITNLVVNKDAVFFLCG 576
Query: 989 PTWPVPDITQALQDIIAADAKEKGINVDLDAA---IEDLKETSRYILEVY 1035
+ +P Q I K+ G D + A +++++++ RYI E +
Sbjct: 577 SSGKMP--IQVRLTFIEM-LKKWGNFSDEETAKKYLKEMEKSDRYIQETW 623
>SPAC1783.01 [C] KOG1158 NADP/FAD dependent oxidoreductase
Length = 583
Score = 73.6 bits (179), Expect = 2e-12
Identities = 70/285 (24%), Positives = 117/285 (40%), Gaps = 26/285 (9%)
Query: 741 DIFGKPP-KRFYESLIDFCTDDKEKSKLENLVSAAGATELKRLQDVEYYTYADIFELFPS 799
D KPP K L + + EKS L L R+ T DI E FPS
Sbjct: 271 DFISKPPTKSLIRLLAEHTLNPVEKSVLLALSDFRQDESYCRICTQSCVTLPDILEAFPS 330
Query: 800 ARPSVEDLVKIIAPLKRREYSIASSQRIHPNEVHLLIVVVDWIDNKGRKRYGQASKFISD 859
P V+ L+ + L R YSI++ + + + V ++ G+ R G + F+ D
Sbjct: 331 CHPPVDHLISALPQLMPRWYSISNDPSLANKRLEMAFTVQEYHSPNGQSRTGICTGFLED 390
Query: 860 LAI------------GSELVVSVKPSVMKLPPSPK----QPVIMSGLGTGLAPFKAIVEE 903
LA+ + V + V + P + + P+ + G G G+APF+ V+
Sbjct: 391 LALAFLKARHDGSLANKKFTVPMFRGVQQNPFAKEFHNDGPMCLIGAGVGIAPFRGFVQR 450
Query: 904 KLWQRQQGYEIGEVYLYLGSRHKREEYLYGELWEA----YKDAGIITHIGAAFSRDQPEK 959
+L G+V++ G R ++ + LY W +K+ SR+ +
Sbjct: 451 RL---ANAACTGKVWIIQGCRDQKLDELYHGEWNTVPGHHKNPKCRAKKLVVESRN-GRR 506
Query: 960 IYIQDRIKENLPELKTAMIDNEGSFYLCGP-TWPVPDITQALQDI 1003
Y+QD ++ + + + G YLCG V +I +AL D+
Sbjct: 507 EYVQDAVRRHGDVIWDVLSHKNGRIYLCGSGNSFVSEIEKALMDV 551
>At1g20020 [C] KOG1158 NADP/FAD dependent oxidoreductase
Length = 369
Score = 72.0 bits (175), Expect = 4e-12
Identities = 68/233 (29%), Positives = 112/233 (47%), Gaps = 17/233 (7%)
Query: 813 PLKRREYSIASS---QRIHPNEVHLLIVVVDWIDNKGRKRYGQASKFISDLAIGSEL-VV 868
P K R YSIASS + V L + + + +++G G S F+ DLA GS++ +
Sbjct: 144 PHKVRLYSIASSALGDLGNSETVSLCVKRLVYTNDQGETVKGVCSNFLCDLAPGSDVKLT 203
Query: 869 SVKPSVMKLPPSPKQPVIMSGLGTGLAPFKAIVEEKLWQRQQGYEI-GEVYLYLGSRHKR 927
M +P P VIM GTG+APF++ + + +++ Y+ G +L+LG
Sbjct: 204 GPVGKEMLMPKDPNATVIMLATGTGIAPFRSFLWKMFFEKHDDYKFNGLAWLFLGV-PTT 262
Query: 928 EEYLYGELWEAYK-DAGIITHIGAAFSRDQP----EKIYIQDRIKENLPELKTAMIDNEG 982
LY E ++ K A + A SR+Q EK+YIQ R+ + EL + +
Sbjct: 263 SSLLYQEEFDKMKAKAPENFRVDYAISREQANDKGEKMYIQTRMAQYAAELWELLKKDNT 322
Query: 983 SFYLCGPTWPVPDITQALQDIIAADAKEKGINVDLDAAIEDLKETSRYILEVY 1035
Y+CG + + + + DI+ + A GI D + LK+ ++ +EVY
Sbjct: 323 FVYMCG----LKGMEKGIDDIMVSLAANDGI--DWFDYKKQLKKAEQWNVEVY 369
>At5g66190 [C] KOG1158 NADP/FAD dependent oxidoreductase
Length = 360
Score = 71.6 bits (174), Expect = 6e-12
Identities = 68/233 (29%), Positives = 109/233 (46%), Gaps = 17/233 (7%)
Query: 813 PLKRREYSIASS---QRIHPNEVHLLIVVVDWIDNKGRKRYGQASKFISDLAIGSEL-VV 868
P K R YSIASS V L + + + ++ G G S F+ DL G E +
Sbjct: 135 PHKLRLYSIASSAIGDFGDSKTVSLCVKRLVYTNDGGEIVKGVCSNFLCDLKPGDEAKIT 194
Query: 869 SVKPSVMKLPPSPKQPVIMSGLGTGLAPFKAIVEEKLWQRQQGYEI-GEVYLYLGSRHKR 927
M +P P +IM G GTG+APF++ + + ++ + Y+ G +L+LG
Sbjct: 195 GPVGKEMLMPKDPNATIIMLGTGTGIAPFRSFLWKMFFEEHEDYKFNGLAWLFLGV-PTS 253
Query: 928 EEYLYGELWEAYKDAGIIT-HIGAAFSRDQP----EKIYIQDRIKENLPELKTAMIDNEG 982
LY E +E K+ + A SR+Q EK+YIQ R+ E EL + +
Sbjct: 254 SSLLYKEEFEKMKEKNPDNFRLDFAVSREQTNEKGEKMYIQTRMAEYAEELWELLKKDNT 313
Query: 983 SFYLCGPTWPVPDITQALQDIIAADAKEKGINVDLDAAIEDLKETSRYILEVY 1035
Y+CG + + + + DI+ + A + GI D + LK + ++ +EVY
Sbjct: 314 FVYMCG----LKGMEKGIDDIMVSLAAKDGI--DWLEYKKQLKRSEQWNVEVY 360
>ECU05g0240 [C] KOG1159 NADP-dependent flavoprotein reductase
Length = 510
Score = 63.9 bits (154), Expect = 1e-09
Identities = 72/326 (22%), Positives = 142/326 (43%), Gaps = 49/326 (15%)
Query: 651 YVVKVKENRRVTPDDYDRYIFHIEFDISGTGMTYDIGEALGVHAKNNLENVQKFLQYYGL 710
YV ++ E R +TPDD+ + I FDI + G+ L + +N N ++F+ Y G+
Sbjct: 186 YVSRLVEKRVLTPDDHFQKIVEFVFDIPDYKEFFP-GDCLSLLPEN--YNYREFMSYNGI 242
Query: 711 NESDIVQVPNKDDHHYLESRTVLQAFVENLDIFGKPPKRFYESLIDFC-----TDDKEKS 765
+ D+ V S +LQ V D +P + F+ +L F T+++
Sbjct: 243 GDGDLDGV---------SSVWMLQNVV---DFNSQPHQPFFFALRHFLGQKNRTEEEILL 290
Query: 766 KLENLVSAAGATELKRLQDVEYYTYADIFELFPSARPSVE--DLVKIIAPLKRREYSIAS 823
K+E + A + D +FE+ R V+ L + + R +S+
Sbjct: 291 KIEEI-----AQDYDLYHDYVIRARRTVFEVLKDLRIKVDIGFLKSFVPAMYPRFFSVTK 345
Query: 824 SQRIHPNEVHLLIVVVDWIDNKGRKRYGQASKFISDLAIGSELVVSVKPSVMKLPPSPKQ 883
+ ++ H+ + +V + R G S+++ L++ + + V+ S +
Sbjct: 346 KKGLY----HITVAIVRYTTFLSEPRRGVCSEYLMSLSLNDVIKIGVERSNLYF---DSD 398
Query: 884 PVIMSGLGTGLAPFKAIVEEKLWQRQQGYEIGEVYLYLGSRHKREEYLYGELWEAYKDAG 943
++ GTG+ +A V E ++ E+ ++ G R+K +++LY + W G
Sbjct: 399 KLLFVCTGTGITLPRACVNE--------FKDKEIVIFYGFRYKNKDFLYPDEW-----TG 445
Query: 944 IITHIGAAFSRDQPEKIYIQDRIKEN 969
+ A SRD +K+Y+QD +++
Sbjct: 446 RNVRMFTAASRD--DKVYVQDVFRKS 469
>At1g30510 [C] KOG1158 NADP/FAD dependent oxidoreductase
Length = 537
Score = 62.0 bits (149), Expect = 5e-09
Identities = 70/249 (28%), Positives = 111/249 (44%), Gaps = 23/249 (9%)
Query: 802 PSVEDLVKIIAPLKRREYSIASSQR---IHPNEVHLLIVVVDWIDNKGRK----RYGQAS 854
P E+ K AP R YSIAS++ L + + D + K + G S
Sbjct: 297 PPGENPKKPGAPHNVRLYSIASTRYGDFFDGKTASLCVRRAVYYDPETGKEDPSKNGVCS 356
Query: 855 KFISDLAIGSEL-VVSVKPSVMKLPPS-PKQPVIMSGLGTGLAPFKAIVEEKLWQRQQGY 912
F+ D G ++ + VM LP S P IM GTG+AP++ + +
Sbjct: 357 NFLCDSKPGDKIQITGPSGKVMLLPESDPNATHIMIATGTGVAPYRGYLRRMFMENVPNK 416
Query: 913 EI-GEVYLYLGSRHKREEYLYGELWEAY-KDAGIITHIGAAFSRDQPEK----IYIQDRI 966
G +L+LG + + LY E + Y KD A SR++ K +Y+QD+I
Sbjct: 417 TFSGLAWLFLGVANT-DSLLYDEEFTKYLKDHPDNFRFDKALSREEKNKKGGKMYVQDKI 475
Query: 967 KENLPELKTAMIDNEGSFYLCGPTWPVPDITQALQDIIAADAKEKGINVDLDAAIEDLKE 1026
+E E+ ++DN Y CG +P I QD + A+E+G + DL + L++
Sbjct: 476 EEYSDEI-FKLLDNGAHIYFCGLKGMMPGI----QDTLKRVAEERGESWDL--KLSQLRK 528
Query: 1027 TSRYILEVY 1035
++ +EVY
Sbjct: 529 NKQWHVEVY 537
>At4g05390 [C] KOG1158 NADP/FAD dependent oxidoreductase
Length = 360
Score = 60.5 bits (145), Expect = 1e-08
Identities = 67/249 (26%), Positives = 111/249 (43%), Gaps = 23/249 (9%)
Query: 802 PSVEDLVKIIAPLKRREYSIASSQ---RIHPNEVHLLIVVVDWIDNKGRK----RYGQAS 854
P E+ K AP R YSIAS++ L + + D + K + G S
Sbjct: 120 PPGENPKKPGAPHNVRLYSIASTRYGDSFDGKTASLCVRRAIYYDPETGKEDPSKAGVCS 179
Query: 855 KFISDLAIGSEL-VVSVKPSVMKLPPS-PKQPVIMSGLGTGLAPFKAIVEEKLWQRQQGY 912
F+ + G ++ + VM LP PK IM GTG+AP++ + + +
Sbjct: 180 NFLCNAKPGDKVKITGPSGKVMLLPEDDPKATHIMIATGTGVAPYRGYLRRMFMENVPNF 239
Query: 913 EI-GEVYLYLGSRHKREEYLYGELWEAY-KDAGIITHIGAAFSRDQPE----KIYIQDRI 966
+ G +L+LG + + LY E + Y KD A SR++ K+Y+QD+I
Sbjct: 240 KFDGLAWLFLGVANS-DSLLYDEEFAGYRKDYPENFRYDKALSREEKNKKGGKMYVQDKI 298
Query: 967 KENLPELKTAMIDNEGSFYLCGPTWPVPDITQALQDIIAADAKEKGINVDLDAAIEDLKE 1026
+E E+ ++DN Y CG +P I QD + A+E+G + + L++
Sbjct: 299 EEYSDEI-FKLLDNGAHIYFCGLKGMMPGI----QDTLKRVAEERG--ESWEQKLTQLRK 351
Query: 1027 TSRYILEVY 1035
++ +EVY
Sbjct: 352 NKQWHVEVY 360
Database: KOG eukaryal database 04/03
Posted date: Apr 14, 2003 1:07 PM
Number of letters in database: 30,389,216
Number of sequences in database: 60,738
Lambda K H
0.316 0.135 0.378
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 58,462,239
Number of Sequences: 60738
Number of extensions: 2528396
Number of successful extensions: 7016
Number of sequences better than 1.0e-05: 29
Number of HSP's better than 0.0 without gapping: 13
Number of HSP's successfully gapped in prelim test: 16
Number of HSP's that attempted gapping in prelim test: 6913
Number of HSP's gapped (non-prelim): 35
length of query: 1035
length of database: 30,389,216
effective HSP length: 117
effective length of query: 918
effective length of database: 23,282,870
effective search space: 21373674660
effective search space used: 21373674660
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.6 bits)