ORF STATUS Function Best COG Functional category Pathways and functional systems
r_klactIV4017 good E KOG3055 Amino acid transport and metabolism Phosphoribosylformimino-5-aminoimidazole carboxamide ribonucleotide (ProFAR) isomerase
Only best alignment is shown:
BLASTP 2.2.3 [May-13-2002]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= r_klactIV4017 1361758 1362558 267
(267 letters)
Database: KOG eukaryal database 04/03
60,738 sequences; 30,389,216 total letters
Searching..................................................done
Color Key for Alignment Scores: 
Score E
Sequences producing significant alignments: (bits) Value
YIL020c [E] KOG3055 Phosphoribosylformimino-5-aminoimidazole car... 372 e-103
SPAC3F10.09 [E] KOG3055 Phosphoribosylformimino-5-aminoimidazole... 258 5e-69
At2g36230 [E] KOG3055 Phosphoribosylformimino-5-aminoimidazole c... 201 1e-51
>YIL020c [E] KOG3055 Phosphoribosylformimino-5-aminoimidazole carboxamide
ribonucleotide (ProFAR) isomerase
Length = 261
Score = 372 bits (955), Expect = e-103
Identities = 179/265 (67%), Positives = 219/265 (82%), Gaps = 5/265 (1%)
Query: 1 MTKFVGCIDLHDGQVKQIVGGTLTDSSKDKVTTNFVSKLPPSHYAKLYHENQVEGCHVIK 60
MTKF+GCIDLH+G+VKQIVGGTLT +D TNFVS+ P S+YAKLY + V+GCHVIK
Sbjct: 1 MTKFIGCIDLHNGEVKQIVGGTLTSKKEDVPKTNFVSQHPSSYYAKLYKDRDVQGCHVIK 60
Query: 61 LGPNNDEAALEALNECPNFLQVGGGITLDNCGYWLKYASKIIVTSFLFDKSTYQFQREKL 120
LGPNND+AA EAL E P FLQVGGGI NC WLK+ASK+IVTS+LF K + FQ ++L
Sbjct: 61 LGPNNDDAAREALQESPQFLQVGGGINDTNCLEWLKWASKVIVTSWLFTKEGH-FQLKRL 119
Query: 121 VKLAEICGKDRLVVDLSCKRVTKPDQEPKWVVAMNKWQTLTDLELNERTFADLCQYTDEF 180
+L E+CGKDR+VVDLSC++ Q+ +W+VAMNKWQTLTDLELN TF +L +YT+EF
Sbjct: 120 ERLTELCGKDRIVVDLSCRKT----QDGRWIVAMNKWQTLTDLELNADTFRELRKYTNEF 175
Query: 181 LVHAADVEGLCNGIDEELVAHLYKWTADIPKVKIVYAGGAKSVDDLRLVEKLSHGKIDLT 240
L+HAADVEGLC GIDE LV+ L++WT D +KIVYAGGAKSVDDL+LV++LSHGK+DLT
Sbjct: 176 LIHAADVEGLCGGIDELLVSKLFEWTKDYDDLKIVYAGGAKSVDDLKLVDELSHGKVDLT 235
Query: 241 FGSALDIFGGSLVKFEDCVQWNHEK 265
FGS+LDIFGG+LVKFEDC +WN ++
Sbjct: 236 FGSSLDIFGGNLVKFEDCCRWNEKQ 260
>SPAC3F10.09 [E] KOG3055 Phosphoribosylformimino-5-aminoimidazole carboxamide
ribonucleotide (ProFAR) isomerase
Length = 264
Score = 258 bits (660), Expect = 5e-69
Identities = 141/262 (53%), Positives = 179/262 (67%), Gaps = 15/262 (5%)
Query: 2 TKFVGCIDLHDGQVKQIVGGTLTDSSKDKVTTNFVSKLPPSHYAKLYHENQVEGCHVIKL 61
T F CID+H GQVKQIVGGTL + + V TN+VS P S+YA+LY N +EG HVI L
Sbjct: 7 TLFRPCIDIHQGQVKQIVGGTLGNDAD--VKTNYVSLKPSSYYAELYKLNHLEGAHVIML 64
Query: 62 GPNNDEAALEALNECPNFLQVGGGITLDNCGYWLKY-ASKIIVTSFLFDKSTYQFQREKL 120
GPN +EAA AL+ P LQ+GGGI + N WL+ ASK+IVTS+LF + QF ++L
Sbjct: 65 GPNCEEAAKTALHTWPGALQIGGGINISNAQNWLQEGASKVIVTSWLFPDA--QFDLDRL 122
Query: 121 VKLAEICGKDRLVVDLSCKRVTKPDQEPKWVVAMNKWQTLTDLELNERTFADLCQYTDEF 180
++ GKDRLVVD+SC+R ++ +W A+NKWQ +T ELNE L QY EF
Sbjct: 123 KAISSKIGKDRLVVDVSCRR-----KDNRWFAAINKWQVMTAFELNEENLDLLSQYCSEF 177
Query: 181 LVHAADVEGLCNGIDEELVAHLYKWTADIPKVKIVYAGGAKSVDDLRLVEKLSHGKIDLT 240
L+HAADVEGLC GIDE+LV L +W K+ YAGG +S++DL LV+KLS GK+DLT
Sbjct: 178 LIHAADVEGLCKGIDEDLVIKLGEWV----KIPTTYAGGGRSIEDLDLVDKLSKGKVDLT 233
Query: 241 FGSALDIFGGSLVKFEDCVQWN 262
GSALDIFGG +++F V WN
Sbjct: 234 IGSALDIFGG-VLEFTRVVAWN 254
>At2g36230 [E] KOG3055 Phosphoribosylformimino-5-aminoimidazole carboxamide
ribonucleotide (ProFAR) isomerase
Length = 304
Score = 201 bits (510), Expect = 1e-51
Identities = 114/270 (42%), Positives = 170/270 (62%), Gaps = 17/270 (6%)
Query: 3 KFVGCIDLHDGQVKQIVGGTLTDSSKDK--VTTNFVSKLPPSHYAKLYHENQVEGCHVIK 60
+F CID+H G+VKQIVG TL D +D + TNF S YAK+Y E+ + G HVI
Sbjct: 45 QFRPCIDIHKGKVKQIVGSTLRDLKEDGSVLVTNFESDKSAEEYAKMYKEDGLTGGHVIM 104
Query: 61 LG--PNNDEAALEALNECPNFLQVGGGITLDNC-GYWLKYASKIIVTSFLFDKSTYQFQR 117
LG P + AA+ AL+ P LQVGGGI +NC Y + AS +IVTS++F+ +
Sbjct: 105 LGADPLSQAAAIGALHAYPGGLQVGGGINSENCMSYIEEGASHVIVTSYVFNNG--KIDL 162
Query: 118 EKLVKLAEICGKDRLVVDLSCKRVTKPDQEPKWVVAMNKWQTLTDLELNERTFADLCQYT 177
E+L + I GK RL++DLSC++ ++ ++ + ++WQ +D+ L+E++ L ++
Sbjct: 163 ERLKDIVSIVGKQRLILDLSCRK-----KDGRYAIVTDRWQKFSDVILDEKSLEFLGGFS 217
Query: 178 DEFLVHAADVEGLCNGIDEELVAHLYKWTADIPKVKIVYAGGAKSVDDLRLVEKLSHGKI 237
DEFLVH DVEG GIDEELVA L ++ + + YAGG +DD+ ++ G++
Sbjct: 218 DEFLVHGVDVEGKKLGIDEELVALLGNYS----PIPVTYAGGVTVMDDVERIKDAGKGRV 273
Query: 238 DLTFGSALDIFGGSLVKFEDCVQWNHEKHA 267
D+T GSALDIFGG+L ++D V W+H++H+
Sbjct: 274 DVTVGSALDIFGGNL-PYKDVVAWHHKQHS 302
Database: KOG eukaryal database 04/03
Posted date: Apr 14, 2003 1:07 PM
Number of letters in database: 30,389,216
Number of sequences in database: 60,738
Lambda K H
0.319 0.138 0.422
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 16,914,219
Number of Sequences: 60738
Number of extensions: 700780
Number of successful extensions: 1557
Number of sequences better than 1.0e-05: 3
Number of HSP's better than 0.0 without gapping: 3
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 1541
Number of HSP's gapped (non-prelim): 3
length of query: 267
length of database: 30,389,216
effective HSP length: 104
effective length of query: 163
effective length of database: 24,072,464
effective search space: 3923811632
effective search space used: 3923811632
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)