ORF STATUS Function Best COG Functional category Pathways and functional systems
r_klactIV4035 suspect: HSP Z KOG1003 Cytoskeleton Actin filament-coating protein tropomyosin
Only best alignment is shown:
BLASTP 2.2.3 [May-13-2002]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= r_klactIV4035 1369333 1366721 -871
(871 letters)
Database: KOG eukaryal database 04/03
60,738 sequences; 30,389,216 total letters
Searching..................................................done
Color Key for Alignment Scores: 
Score E
Sequences producing significant alignments: (bits) Value
Hs4507649 [Z] KOG1003 Actin filament-coating protein tropomyosin 67 1e-10
YDL058w [U] KOG0946 ER-Golgi vesicle-tethering protein p115 66 3e-10
Hs11321579 [Z] KOG0161 Myosin class II heavy chain 65 6e-10
Hs7705348 [Z] KOG0247 Kinesin-like protein 64 8e-10
Hs11342672 [Z] KOG0161 Myosin class II heavy chain 63 2e-09
Hs4507659 [S] KOG4674 Uncharacterized conserved coiled-coil protein 62 3e-09
7291892 [Z] KOG0161 Myosin class II heavy chain 62 5e-09
Hs15313972 [Z] KOG0161 Myosin class II heavy chain 60 1e-08
YNL079c [Z] KOG1003 Actin filament-coating protein tropomyosin 60 1e-08
Hs4557773 [Z] KOG0161 Myosin class II heavy chain 60 2e-08
Hs20558376 [Z] KOG0161 Myosin class II heavy chain 60 2e-08
7292701_2 [S] KOG4415 Uncharacterized conserved protein 60 2e-08
SPAC688.11 [Z] KOG0980 Actin-binding protein SLA2/Huntingtin-int... 59 2e-08
Hs20542063 [Z] KOG0161 Myosin class II heavy chain 59 2e-08
Hs12667788 [Z] KOG0161 Myosin class II heavy chain 59 2e-08
SPAC1486.04c [S] KOG4674 Uncharacterized conserved coiled-coil p... 59 3e-08
Hs7669506 [Z] KOG0161 Myosin class II heavy chain 59 3e-08
Hs19923140 [Z] KOG4280 Kinesin-like protein 59 3e-08
Hs11024712 [Z] KOG0161 Myosin class II heavy chain 59 3e-08
Hs4505301 [Z] KOG0161 Myosin class II heavy chain 59 4e-08
SPAC1556.01c [L] KOG0962 DNA repair protein RAD50 ABC-type ATPas... 58 6e-08
CE09349 [Z] KOG0161 Myosin class II heavy chain 58 7e-08
7298379 [ZR] KOG4568 Cytoskeleton-associated protein and related... 58 7e-08
YIL138c [Z] KOG1003 Actin filament-coating protein tropomyosin 57 9e-08
CE04618 [Z] KOG0161 Myosin class II heavy chain 57 9e-08
Hs13259510 [DZ] KOG0971 Microtubule-associated protein dynactin ... 57 1e-07
Hs13259508 [DZ] KOG0971 Microtubule-associated protein dynactin ... 57 1e-07
Hs8923940 [Z] KOG0161 Myosin class II heavy chain 57 2e-07
Hs8923838 [S] KOG4643 Uncharacterized coiled-coil protein 57 2e-07
SPAC17C9.03 [J] KOG0401 Translation initiation factor 4F ribosom... 56 2e-07
Hs5453642 [D] KOG0018 Structural maintenance of chromosome prote... 56 2e-07
Hs14764231 [D] KOG0018 Structural maintenance of chromosome prot... 56 2e-07
CE07306 [Z] KOG0161 Myosin class II heavy chain 56 2e-07
7303885 [U] KOG4809 Rab6 GTPase-interacting protein involved in ... 56 2e-07
Hs4503509 [J] KOG2072 Translation initiation factor 3 subunit a ... 56 3e-07
Hs20539050 [Z] KOG1003 Actin filament-coating protein tropomyosin 56 3e-07
Hs13124879 [Z] KOG0161 Myosin class II heavy chain 56 3e-07
Hs13124877 [Z] KOG0161 Myosin class II heavy chain 56 3e-07
Hs13124875 [Z] KOG0161 Myosin class II heavy chain 56 3e-07
CE27096 [BDL] KOG0979 Structural maintenance of chromosome prote... 55 4e-07
Hs4759044 [T] KOG0612 Rho-associated coiled-coil containing prot... 55 5e-07
Hs20536595 [T] KOG0612 Rho-associated coiled-coil containing pro... 55 5e-07
At1g79830 [K] KOG4673 Transcription factor TMF TATA element modu... 55 5e-07
At1g04600 [Z] KOG0160 Myosin class V heavy chain 55 5e-07
CE09197 [Z] KOG0161 Myosin class II heavy chain 55 6e-07
YKR095w [S] KOG4674 Uncharacterized conserved coiled-coil protein 54 8e-07
Hs14772793 [Z] KOG0161 Myosin class II heavy chain 54 8e-07
Hs4506751 [ZR] KOG4568 Cytoskeleton-associated protein and relat... 54 1e-06
CE08691 [U] KOG0999 Microtubule-associated protein Bicaudal-D 54 1e-06
Hs20070123 [Z] KOG1003 Actin filament-coating protein tropomyosin 54 1e-06
7298332 [BD] KOG0996 Structural maintenance of chromosome protei... 54 1e-06
ECU04g1000 [Z] KOG0161 Myosin class II heavy chain 53 2e-06
CE27133 [Z] KOG0161 Myosin class II heavy chain 53 2e-06
CE22238 [S] KOG0992 Uncharacterized conserved protein 53 2e-06
CE03665 [Z] KOG0161 Myosin class II heavy chain 53 2e-06
Hs4758648 [Z] KOG0240 Kinesin (SMY1 subfamily) 53 2e-06
7303561 [S] KOG4674 Uncharacterized conserved coiled-coil protein 53 2e-06
7303132 [BD] KOG0933 Structural maintenance of chromosome protei... 53 2e-06
YJL074c [D] KOG0964 Structural maintenance of chromosome protein... 52 3e-06
YHR023w [Z] KOG0161 Myosin class II heavy chain 52 3e-06
SPAC1F3.06c [S] KOG4674 Uncharacterized conserved coiled-coil pr... 52 3e-06
Hs9055284 [Z] KOG0160 Myosin class V heavy chain 52 3e-06
Hs7661992 [KRT] KOG4572 Predicted DNA-binding transcription fact... 52 3e-06
CE27289 [K] KOG0963 Transcription factor/CCAAT displacement prot... 52 3e-06
CE27288_1 [K] KOG0963 Transcription factor/CCAAT displacement pr... 52 3e-06
SPAC664.10 [Z] KOG0239 Kinesin (KAR3 subfamily) 52 4e-06
Hs4758956 [TZ] KOG3632 Peripheral benzodiazepine receptor PRAX-1 52 4e-06
CE27954 [Z] KOG0613 Projectin/twitchin and related proteins 52 4e-06
7296430 [TV] KOG4297 C-type lectin 52 4e-06
Hs4758650 [Z] KOG0240 Kinesin (SMY1 subfamily) 52 5e-06
YFR016c [S] KOG1181 FOG: Low-complexity 51 7e-06
Hs4826808 [Z] KOG0240 Kinesin (SMY1 subfamily) 51 7e-06
7299993 [Z] KOG1003 Actin filament-coating protein tropomyosin 51 7e-06
SPAP4C9.01c [L] KOG0962 DNA repair protein RAD50 ABC-type ATPase... 51 9e-06
Hs4502443 [Z] KOG0516 Dystonin GAS (Growth-arrest-specific prote... 51 9e-06
Hs16554453 [O] KOG0978 E3 ubiquitin ligase involved in syntaxin ... 51 9e-06
Hs13470092 [R] KOG1729 FYVE finger containing protein 51 9e-06
At5g54670 [Z] KOG0239 Kinesin (KAR3 subfamily) 51 9e-06
At4g27180 [Z] KOG0239 Kinesin (KAR3 subfamily) 51 9e-06
7303398 [R] KOG2579 Ficolin and related extracellular proteins 51 9e-06
>Hs4507649 [Z] KOG1003 Actin filament-coating protein tropomyosin
Length = 284
Score = 67.0 bits (162), Expect = 1e-10
Identities = 64/247 (25%), Positives = 122/247 (48%), Gaps = 30/247 (12%)
Query: 464 KSVYDKLQYDEDQHQA--KLALYSKEQDERYETKAQEYEEKIQSIQ-------AEIAELD 514
K D+ + E++ QA K ++++ E+Y +E +EK++ + A++A L+
Sbjct: 30 KQAEDRCKQLEEEQQALQKKLKGTEDEVEKYSESVKEAQEKLEQAEKKATDAEADVASLN 89
Query: 515 AQMEQVRLE---HEEKL-----KLKQVEKSQALLETNVKHINAKGDLYKQTEEIKNQTIS 566
+++ V E +E+L KL++ EK+ E +K I + K E+++ Q +
Sbjct: 90 RRIQLVEEELDRAQERLATALQKLEEAEKAADESERGMKVIENRA--MKDEEKMELQEMQ 147
Query: 567 DKEDKEVAHQT---VQSEIDELLLLKDEVAKENQEHE---SKVEELTAELDNKTSALNES 620
KE K +A + + +L++L+ E+ + + E S+ +L EL AL
Sbjct: 148 LKEAKHIAEDSDRKYEEVARKLVILEGELERSEERAEVAESRARQLEEELRTMDQALKSL 207
Query: 621 LAKKDETNAEIQALEEEKARLEQEIKEAQ---ELHQQNVSKIESI--DNKEYLPKVNEIN 675
+A ++E + + EEE LE+++KEA+ E +++V+K+E D +E L E N
Sbjct: 208 MASEEEYSTKEDKYEEEIKLLEEKLKEAETRAEFAERSVAKLEKTIDDLEETLASAKEEN 267
Query: 676 TEISSLL 682
EI L
Sbjct: 268 VEIHQTL 274
>YDL058w [U] KOG0946 ER-Golgi vesicle-tethering protein p115
Length = 1790
Score = 65.9 bits (159), Expect = 3e-10
Identities = 60/248 (24%), Positives = 122/248 (49%), Gaps = 45/248 (18%)
Query: 464 KSVYDKLQYDEDQHQAKLALYSKEQ---DERYETKAQEYEEKIQSIQAEIAELDAQMEQV 520
K+ ++L+ +++ Q K + KE+ +E T QEY EKI +++ E+ +
Sbjct: 1345 KNAEEQLEKLKNEIQIKNQAFEKERKLLNEGSSTITQEYSEKINTLEDEL---------I 1395
Query: 521 RLEHEEKLKLKQVEKSQALLETNVKHINAKGDLYKQTEEIKNQTISDKEDKEVAHQTVQS 580
RL++E +LK K+++ +++ E++ ++S+ E E T++S
Sbjct: 1396 RLQNENELKAKEIDNTRS--------------------ELEKVSLSNDELLEEKQNTIKS 1435
Query: 581 EIDELLLLKDEVAKENQEHESKVEELTAELDNK--TSALNESLAKKDETNAEIQ----AL 634
DE+L KD++ + ++ + L+ E DNK +L E L E+ A+++ L
Sbjct: 1436 LQDEILSYKDKITRNDE------KLLSIERDNKRDLESLKEQLRAAQESKAKVEEGLKKL 1489
Query: 635 EEEKARLEQEIKEAQELHQQNVSKIESIDNKEYLPKVNEINTEISSLLASLGLIQQEIAN 694
EEE ++ + E+++++E+ ++ S IES + E + I L S +++I N
Sbjct: 1490 EEESSKEKAELEKSKEMMKKLESTIES-NETELKSSMETIRKSDEKLEQSKKSAEEDIKN 1548
Query: 695 QKVEFSSV 702
+ E S +
Sbjct: 1549 LQHEKSDL 1556
Score = 63.2 bits (152), Expect = 2e-09
Identities = 52/215 (24%), Positives = 108/215 (50%), Gaps = 13/215 (6%)
Query: 469 KLQYDEDQHQAKLALYSKEQDERYETKAQEYEEKIQSIQAEIAELDAQMEQVRLEHEEKL 528
KL+ + + +A+L SKE ++ E+ + E +++S I + D ++EQ + EE +
Sbjct: 1488 KLEEESSKEKAELEK-SKEMMKKLESTIESNETELKSSMETIRKSDEKLEQSKKSAEEDI 1546
Query: 529 KLKQVEKSQALLETNVKHINAKGDLYKQTEEIKNQT-ISDKEDKEVAHQTVQSEIDELLL 587
K Q EKS + N K EE+K++ I K E+ +TV+ E++
Sbjct: 1547 KNLQHEKSDLISRINESE--------KDIEELKSKLRIEAKSGSEL--ETVKQELNNAQE 1596
Query: 588 LKDEVAKENQEHESKVEELTAELDNKTSALNESLAKKDETNAEIQALEEEKARLEQEIKE 647
A+EN +SK+E++ EL +K + + + +K+ + ++ LE+E +Q+ ++
Sbjct: 1597 KIRINAEENTVLKSKLEDIERELKDKQAEIKSNQEEKELLTSRLKELEQELDSTQQKAQK 1656
Query: 648 AQELHQQNVSKIESIDNKEYLPKVNEINTEISSLL 682
++E + V K + ++ + K + T+ + L+
Sbjct: 1657 SEEERRAEVRKFQ-VEKSQLDEKAMLLETKYNDLV 1690
Score = 62.4 bits (150), Expect = 3e-09
Identities = 64/279 (22%), Positives = 129/279 (45%), Gaps = 41/279 (14%)
Query: 465 SVYDKLQYDEDQHQAKLALYSKEQDERYETKAQEYEEKIQSIQAEIA------------- 511
S+ L+ E +H+ LA K+ +E+ K ++Y E+I + EI
Sbjct: 1142 SLRANLESLEKEHE-DLAAQLKKYEEQIANKERQYNEEISQLNDEITSTQQENESIKKKN 1200
Query: 512 -ELDAQMEQVRLEHEEKLKLKQVEKSQALL---ETNVKHINAKGDLYKQTEEIKNQTISD 567
EL+ +++ ++ EE+ LK+ E L E K+ + L + + ++++T+
Sbjct: 1201 DELEGEVKAMKSTSEEQSNLKKSEIDALNLQIKELKKKNETNEASLLESIKSVESETVKI 1260
Query: 568 KEDKEVAH--QTVQSEIDELLLLKDEVAKENQEHESKVEELTAELDNKTSALNESLAK-- 623
KE ++ + + SE+++ L ++ + E + + E++ ELD KT+ L L K
Sbjct: 1261 KELQDECNFKEKEVSELEDKLKASEDKNSKYLELQKESEKIKEELDAKTTELKIQLEKIT 1320
Query: 624 -----KDETNAEIQAL-----------EEEKARLEQEIK---EAQELHQQNVSKIESIDN 664
K+++ +E+ L EE+ +L+ EI+ +A E ++ +++ S
Sbjct: 1321 NLSKAKEKSESELSRLKKTSSEERKNAEEQLEKLKNEIQIKNQAFEKERKLLNEGSSTIT 1380
Query: 665 KEYLPKVNEINTEISSLLASLGLIQQEIANQKVEFSSVT 703
+EY K+N + E+ L L +EI N + E V+
Sbjct: 1381 QEYSEKINTLEDELIRLQNENELKAKEIDNTRSELEKVS 1419
Score = 59.3 bits (142), Expect = 2e-08
Identities = 69/250 (27%), Positives = 119/250 (47%), Gaps = 32/250 (12%)
Query: 456 RTQEGYVSKSVYDKLQYDEDQHQAKLALYSKEQDERYETKAQEYEEKIQSIQAEIAELDA 515
+T+E +SKS K D+++++++L KE+ E T E KI + EL+A
Sbjct: 1036 QTKEEIISKSDSSK-----DEYESQISLL-KEKLETATTANDENVNKISELTKTREELEA 1089
Query: 516 QMEQVR-LEHEEKLKLKQVEKSQALLETNVKHINA-KGDLYKQTEEIKNQTIS------- 566
++ + L++E + KL+ EK+ ++ N +H+ K L K+ E K Q S
Sbjct: 1090 ELAAYKNLKNELETKLETSEKALKEVKENEEHLKEEKIQLEKEATETKQQLNSLRANLES 1149
Query: 567 -DKEDKEVAHQTVQSEI----------DELLLLKDEVAKENQEHES---KVEELTAELD- 611
+KE +++A Q + E +E+ L DE+ QE+ES K +EL E+
Sbjct: 1150 LEKEHEDLAAQLKKYEEQIANKERQYNEEISQLNDEITSTQQENESIKKKNDELEGEVKA 1209
Query: 612 NKTSALNESLAKKDETNAEIQALEEEKARLEQEIKEAQELHQQNVSKIESIDNKEYLPKV 671
K+++ +S KK E +A ++E K + E EA L + E++ KE +
Sbjct: 1210 MKSTSEEQSNLKKSEIDALNLQIKELKKK--NETNEASLLESIKSVESETVKIKELQDEC 1267
Query: 672 NEINTEISSL 681
N E+S L
Sbjct: 1268 NFKEKEVSEL 1277
Score = 55.8 bits (133), Expect = 3e-07
Identities = 62/250 (24%), Positives = 116/250 (45%), Gaps = 31/250 (12%)
Query: 463 SKSVYDKLQYDEDQHQAKLALYS---KEQDERYETKAQEYEEKIQSIQAEIAELDAQMEQ 519
SK + KL+ + ++ +L ++ DE+ E + EE I+++Q E ++L +++ +
Sbjct: 1503 SKEMMKKLESTIESNETELKSSMETIRKSDEKLEQSKKSAEEDIKNLQHEKSDLISRINE 1562
Query: 520 VRLEHEE-KLKLKQVEKSQALLETNVKHINAKGDLYKQTEEIKNQTISDKEDKEVAHQTV 578
+ EE K KL+ KS + LET + +N + + E S ED E +
Sbjct: 1563 SEKDIEELKSKLRIEAKSGSELETVKQELNNAQEKIRINAEENTVLKSKLEDIERELKDK 1622
Query: 579 QSEIDELLLLKDEVAKENQEHE----SKVEELTAELDNKTSALNESLAKKDETNAEIQAL 634
Q+EI K NQE + S+++EL ELD+ +S ++E AE++
Sbjct: 1623 QAEI-----------KSNQEEKELLTSRLKELEQELDSTQQKAQKS---EEERRAEVRKF 1668
Query: 635 EEEKARLEQEIKEAQELHQQNVSKIESIDNKEYLPKVNE--INTEISSLLASLGLIQQEI 692
+ EK++L+++ + +K + NKE K +E + S + + +E+
Sbjct: 1669 QVEKSQLDEKAMLLE-------TKYNDLVNKEQAWKRDEDTVKKTTDSQRQEIEKLAKEL 1721
Query: 693 ANQKVEFSSV 702
N K E S +
Sbjct: 1722 DNLKAENSKL 1731
Score = 55.8 bits (133), Expect = 3e-07
Identities = 39/186 (20%), Positives = 96/186 (50%), Gaps = 6/186 (3%)
Query: 486 KEQDERYETKAQEYEEKIQSIQAEIAELDAQMEQVRLE---HEEKLKLKQVEKSQALLET 542
KE+ + E +A E ++++ S++A + L+ + E + + +EE++ K+ + ++ + +
Sbjct: 1123 KEEKIQLEKEATETKQQLNSLRANLESLEKEHEDLAAQLKKYEEQIANKERQYNEEISQL 1182
Query: 543 NVKHINAKGD---LYKQTEEIKNQTISDKEDKEVAHQTVQSEIDELLLLKDEVAKENQEH 599
N + + + + + K+ +E++ + + K E +SEID L L E+ K+N+ +
Sbjct: 1183 NDEITSTQQENESIKKKNDELEGEVKAMKSTSEEQSNLKKSEIDALNLQIKELKKKNETN 1242
Query: 600 ESKVEELTAELDNKTSALNESLAKKDETNAEIQALEEEKARLEQEIKEAQELHQQNVSKI 659
E+ + E ++++T + E + + E+ LE++ E + + EL +++
Sbjct: 1243 EASLLESIKSVESETVKIKELQDECNFKEKEVSELEDKLKASEDKNSKYLELQKESEKIK 1302
Query: 660 ESIDNK 665
E +D K
Sbjct: 1303 EELDAK 1308
Score = 53.1 bits (126), Expect = 2e-06
Identities = 57/253 (22%), Positives = 113/253 (44%), Gaps = 21/253 (8%)
Query: 458 QEGYVSKSV--YDKLQYDEDQHQAKLALYSKEQDERYETKAQEYEEKIQSIQAEIAELDA 515
++ ++SK + Y D AKL K Y+ E E I++++ E
Sbjct: 935 EKEHISKELVEYKSRFQSHDNLVAKLTEKLKSLANNYKDMQAENESLIKAVEESKNESSI 994
Query: 516 QMEQVRLEHEEKLKLK---QVEKSQALLETNVKHINAK-GDLYKQTEEIKNQTISDKEDK 571
Q+ ++ + + + K Q+E+ +E N++ + DL + EEI +++ S K++
Sbjct: 995 QLSNLQNKIDSMSQEKENFQIERGS--IEKNIEQLKKTISDLEQTKEEIISKSDSSKDEY 1052
Query: 572 EVAHQTVQSEIDELLLLKDEVAKENQEHESKVEELTAELDNKTSALNESLAKKDETNAEI 631
E ++ +++ DE + E EEL AEL + NE K + + +
Sbjct: 1053 ESQISLLKEKLETATTANDENVNKISELTKTREELEAELAAYKNLKNELETKLETSEKAL 1112
Query: 632 QALEEEKARLEQE----IKEAQELHQQNVSKIESIDNKEYLPKVNEINTEISSLLASLGL 687
+ ++E + L++E KEA E QQ S ++++ E E L A L
Sbjct: 1113 KEVKENEEHLKEEKIQLEKEATETKQQLNSLRANLESLE---------KEHEDLAAQLKK 1163
Query: 688 IQQEIANQKVEFS 700
+++IAN++ +++
Sbjct: 1164 YEEQIANKERQYN 1176
>Hs11321579 [Z] KOG0161 Myosin class II heavy chain
Length = 1938
Score = 64.7 bits (156), Expect = 6e-10
Identities = 56/211 (26%), Positives = 106/211 (49%), Gaps = 32/211 (15%)
Query: 485 SKEQDERYETKAQEYEEKIQSIQAEIAELDAQMEQVR---LEHEEKLKLKQVEKSQALLE 541
+KE+ R E + +E EEK+ S+ E +L Q++ ++ EE+ + + KS+ LLE
Sbjct: 863 TKEELARSEARRKELEEKMVSLLQEKNDLQLQVQSETENLMDAEERCE--GLIKSKILLE 920
Query: 542 TNVKHINAKGDLYKQTEEIKNQTISDKEDKEVAHQTVQSEIDELLLLKDEVAKENQEHES 601
VK + + ++ EE+ ++ ++ K + E +++ +ID+L L +V KE E+
Sbjct: 921 AKVKELTER---LEEEEEMNSELVAKKRNLEDKCSSLKRDIDDLELTLTKVEKEKHATEN 977
Query: 602 KVEELTAELDNKTSALNESLAKKDETNAEIQALEEEKARLEQEIKEAQELHQQNVSKIES 661
KV+ L+ E+ ALEE ++L +E K QE HQQ + ++
Sbjct: 978 KVKNLSEEM---------------------TALEENISKLTKEKKSLQEAHQQTLDDLQV 1016
Query: 662 IDNKEYLPKVNEINTEISSLLASL-GLIQQE 691
++K + + +IN ++ L G ++QE
Sbjct: 1017 EEDK--VNGLIKINAKLEQQTDDLEGSLEQE 1045
Score = 53.9 bits (128), Expect = 1e-06
Identities = 60/269 (22%), Positives = 122/269 (45%), Gaps = 22/269 (8%)
Query: 455 VRTQEGYVSKSVYDKLQYDEDQHQAKLALYSK--EQDERYETKAQEYEEKIQSIQAEIAE 512
++TQ G +S V +K ++K AL + E + E + + ++Q+ +
Sbjct: 1284 LQTQNGELSHRVEEKESLISQLTKSKQALTQQLEELKRQMEEETKAKNAMAHALQSSRHD 1343
Query: 513 LDAQMEQVRLEHEEKLKLKQVEKSQALLETNVKHINAKGDLYKQTEEI---KNQTISDKE 569
D EQ E E K +L++ S+A E + D ++TEE+ K + +
Sbjct: 1344 CDLLREQYEEEQEAKAELQRA-LSKANSEVAQWKTKYETDAIQRTEELEEAKKKLAQRLQ 1402
Query: 570 DKEVAHQTVQSEIDELLLLKDEVAKENQEHESKVEE---LTAELDNKTSALNESLA---- 622
+ E +T S+ L K + E ++ +E A LD K ++ LA
Sbjct: 1403 EAEEKTETANSKCASLEKTKQRLQGEVEDLMRDLERSHTACATLDKKQRNFDKVLAEWKQ 1462
Query: 623 KKDETNAEIQALEEEKARLEQEIKEAQELHQQNVSKIESI--DNKEYLPKVNEINTEISS 680
K DE+ AE++A ++E L E+ + + +++ V ++E++ +NK +++++ +I+
Sbjct: 1463 KLDESQAELEAAQKESRSLSTELFKMRNAYEEVVDQLETLRRENKNLQEEISDLTEQIAE 1522
Query: 681 LLASL-------GLIQQEIANQKVEFSSV 702
+L L++QE ++ +V V
Sbjct: 1523 TGKNLQEAEKTKKLVEQEKSDLQVALEEV 1551
>Hs7705348 [Z] KOG0247 Kinesin-like protein
Length = 1780
Score = 64.3 bits (155), Expect = 8e-10
Identities = 52/207 (25%), Positives = 104/207 (50%), Gaps = 9/207 (4%)
Query: 498 EYEEKIQSIQAEIAELDAQMEQVRLEHEEKLKLKQ--VEKSQALL--ETNVKHINAK-GD 552
E + + +A+I EL+ +E ++E KL+Q +EK +L E N+K D
Sbjct: 1111 ELTQGVTCYKAKIKELETILETQKVERSHSAKLEQDILEKESIILKLERNLKEFQEHLQD 1170
Query: 553 LYKQTEEIKNQTISDKEDKEVAHQTVQSEIDELLLLKDEVAKENQEHESKVEELTAELDN 612
K T+++ + + KE+ +Q ++ LL LK+E + N++ K++E +
Sbjct: 1171 SVKNTKDLNVKELKLKEEITQLTNNLQ-DMKHLLQLKEEEEETNRQETEKLKEELSASSA 1229
Query: 613 KTSALNESLAKKDETNAEI-QALEEEKARLEQEIKEAQELHQQNVSKIESIDNKEYLPKV 671
+T L L +K+E A++ + L + K +++Q KE + ++ K+ I E K
Sbjct: 1230 RTQNLKADLQRKEEDYADLKEKLTDAKKQIKQVQKEVSVMRDED--KLLRIKINELEKKK 1287
Query: 672 NEINTEISSLLASLGLIQQEIANQKVE 698
N+ + E+ ++ +++++ NQKVE
Sbjct: 1288 NQCSQELDMKQRTIQQLKEQLNNQKVE 1314
>Hs11342672 [Z] KOG0161 Myosin class II heavy chain
Length = 1940
Score = 63.2 bits (152), Expect = 2e-09
Identities = 59/218 (27%), Positives = 104/218 (47%), Gaps = 36/218 (16%)
Query: 484 YSKEQDE--RYETKAQEYEEKIQSIQAEIAELDAQME---QVRLEHEEKLKLKQVEKSQA 538
+ K +DE + E K +E EEK+ ++ E +L Q++ + L+ EE+ Q+ K++
Sbjct: 857 FQKTKDELAKSEAKRKELEEKLVTLVQEKNDLQLQVQAESENLLDAEERCD--QLIKAKF 914
Query: 539 LLETNVKHINAKGDLYKQTEEIKNQTISDKEDKEVAHQTVQSEIDELLLLKDEVAKENQE 598
LE +K + + + EEI + + K E ++ +ID+L L +V KE
Sbjct: 915 QLEAKIKEVTERAE---DEEEINAELTAKKRKLEDECSELKKDIDDLELTLAKVEKEKHA 971
Query: 599 HESKVEELTAELDNKTSALNESLAKKDETNAEIQALEEEKARLEQEIKEAQELHQQNVSK 658
E+KV+ LT EL S L+E++AK L +E K QE HQQ +
Sbjct: 972 TENKVKNLTEEL----SGLDETIAK-----------------LTREKKALQEAHQQALDD 1010
Query: 659 IESIDNKEYLPKVNEINTEISSLLASLGLIQQEIANQK 696
+++ ++ KVN +N S L + ++ + +K
Sbjct: 1011 LQAEED-----KVNSLNKTKSKLEQQVEDLESSLEQEK 1043
Score = 51.2 bits (121), Expect = 7e-06
Identities = 48/236 (20%), Positives = 105/236 (44%), Gaps = 39/236 (16%)
Query: 468 DKLQYDEDQHQAKLA---LYSKEQDERYETKAQEYEEKIQSIQAEIAELDAQME-----Q 519
DK Q DE + L SK +DE +T ++++KI+ +QA I EL+ ++E +
Sbjct: 1073 DKQQLDERLKKKDFEYCQLQSKVEDE--QTLGLQFQKKIKELQARIEELEEEIEAERATR 1130
Query: 520 VRLEHEEKLKLKQVEKSQALLETNVKHINAKGDLYKQTEEIKNQTISDKEDKEVAHQTVQ 579
+ E + +++E+ LE + + +L K+ E + D E+ + H+ +
Sbjct: 1131 AKTEKQRSDYARELEELSERLEEAGGVTSTQIELNKKREAEFLKLRRDLEEATLQHEAMV 1190
Query: 580 S---------------EIDELLLLKDEVAKENQEHESKVEELTAELDNKTSA-------- 616
+ +ID L +K ++ KE E + ++++L++ +++ + +
Sbjct: 1191 ATLRKKHADSVAELGEQIDNLQRVKQKLEKEKSEFKLEIDDLSSSMESVSKSKANLEKIC 1250
Query: 617 ------LNESLAKKDETNAEIQALEEEKARLEQEIKEAQELHQQNVSKIESIDNKE 666
L+E+ K +E + L +K+RL+ E E ++ S + + +
Sbjct: 1251 RTLEDQLSEARGKNEEIQRSLSELTTQKSRLQTEAGELSRQLEEKESIVSQLSRSK 1306
>Hs4507659 [S] KOG4674 Uncharacterized conserved coiled-coil protein
Length = 2349
Score = 62.4 bits (150), Expect = 3e-09
Identities = 55/212 (25%), Positives = 109/212 (50%), Gaps = 26/212 (12%)
Query: 464 KSVYDKLQYDEDQHQAKLALYSKEQDERYET--KAQEYEEKIQSIQAEIAELDAQMEQVR 521
K+ Y++L+ +D+ A S + E++ + + QE +E + + + L++Q+E ++
Sbjct: 1442 KTQYEELKAQQDKVMETSAQSSGDHQEQHVSVQEMQELKETLNQAETKSKSLESQVENLQ 1501
Query: 522 LEHEEK-LKLKQVEKSQALLETNVKHINAKGDLYKQT--EEIKNQTISDKEDK-EVAHQT 577
EK + + +++ L++ + + + DL +T EE Q I++KE+K A
Sbjct: 1502 KTLSEKETEARNLQEQTVQLQSELSRL--RQDLQDRTTQEEQLRQQITEKEEKTRKAIVA 1559
Query: 578 VQSEIDELLLLKDEVAKENQEHESKVEELTAELDNKTSALNESLAKKDETNAEIQALEEE 637
+S+I L +KD++ KEN+ EL + AL++ +KDE + I AL+ +
Sbjct: 1560 AKSKIAHLAGVKDQLTKENE-----------ELKQRNGALDQ---QKDELDVRITALKSQ 1605
Query: 638 K----ARLEQEIKEAQELHQQNVSKIESIDNK 665
+RLE+E++E QE H + + + NK
Sbjct: 1606 YEGRISRLERELREHQERHLEQRDEPQEPSNK 1637
>7291892 [Z] KOG0161 Myosin class II heavy chain
Length = 2056
Score = 61.6 bits (148), Expect = 5e-09
Identities = 59/252 (23%), Positives = 113/252 (44%), Gaps = 26/252 (10%)
Query: 468 DKLQYDEDQHQAKLALYSKEQDERYETKAQEYEEKIQ--SIQAEIAELDAQMEQVRLEHE 525
++L D+ Q Q K + E + K Q E ++Q +QA++A+ + ++ Q L +
Sbjct: 1124 ERLHKDQQQRQESDRSKRKIETEVADLKEQLNERRVQVDEMQAQLAKREEELTQTLLRID 1183
Query: 526 EKLKLKQV-EKSQALLETNVKHIN---------------AKGDLYKQTEEIKNQTISDKE 569
E+ K +K+Q LE+ + I + DL ++ E +KN+ + D
Sbjct: 1184 EESATKATAQKAQRELESQLAEIQEDLEAEKAARAKAEKVRRDLSEELEALKNELL-DSL 1242
Query: 570 DKEVAHQTVQSEID-ELLLLKDEVAKENQEHESKVEELTAELDNKTSALNESLAKKDETN 628
D A Q ++S+ + EL LK + +E HE + ++ + + +++N+ L +
Sbjct: 1243 DTTAAQQELRSKREQELATLKKSLEEETVNHEGVLADMRHKHSQELNSINDQLENLRKAK 1302
Query: 629 AEIQ----ALEEEKARLEQEIKEAQELHQQNVSKIESIDNK--EYLPKVNEINTEISSLL 682
++ LE E A L E++ Q+N + + +++ E K+ EI S L
Sbjct: 1303 TVLEKAKGTLEAENADLATELRSVNSSRQENDRRRKQAESQIAELQVKLAEIERARSELQ 1362
Query: 683 ASLGLIQQEIAN 694
+QQE N
Sbjct: 1363 EKCTKLQQEAEN 1374
Score = 57.0 bits (136), Expect = 1e-07
Identities = 83/431 (19%), Positives = 165/431 (38%), Gaps = 75/431 (17%)
Query: 474 EDQHQAKLALYSKEQDERYETKAQEYEEKIQSIQAEIAELDAQMEQVRLEHEEKLKLKQV 533
E++ + LAL +++ + E Q+ EE+++ + E A Q+E+V+L+ K+K+
Sbjct: 1015 EEEEERVLALGGEKK--KLELNIQDLEEQLE--EEEAARQKLQLEKVQLD----AKIKKY 1066
Query: 534 EKSQALLETNVKHINAKGDLYKQTEEIKNQTISDKEDK-------EVAHQTVQSEIDELL 586
E+ AL + + + + L ++ +QT++++E+K + H+ SE++E L
Sbjct: 1067 EEDLALTDDQNQKLLKEKKLLEERANDLSQTLAEEEEKAKHLAKLKAKHEATISELEERL 1126
Query: 587 LLKDEVAKENQEHESKVEELTAELDNKTSALNESLAKKDETNAEIQALEEEKA----RLE 642
+ +E+ + K+E A+L + LNE + DE A++ EEE R++
Sbjct: 1127 HKDQQQRQESDRSKRKIETEVADLKEQ---LNERRVQVDEMQAQLAKREEELTQTLLRID 1183
Query: 643 QEI-------KEAQELHQQNVSKIESID-NKEYLPKVNEINTEISSLLASLGLIQQEIAN 694
+E K +EL Q E ++ K K ++ ++S L +L N
Sbjct: 1184 EESATKATAQKAQRELESQLAEIQEDLEAEKAARAKAEKVRRDLSEELEAL-------KN 1236
Query: 695 QKVEFSSVTXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXTEYEKQAEEARLKHEEEL 754
+ ++ T +K EE + HE L
Sbjct: 1237 ELLDSLDTTAAQQELRSKREQELAT-------------------LKKSLEEETVNHEGVL 1277
Query: 755 ANLKQTHDXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXGE-KAIEAQQRGN---- 809
A+++ H E +++ + ++ N
Sbjct: 1278 ADMRHKHSQELNSINDQLENLRKAKTVLEKAKGTLEAENADLATELRSVNSSRQENDRRR 1337
Query: 810 --------------PEDKRLEAEHEEKLRRQAEAASAVENALKSSNKKTKAAVPPANTTN 855
E +R +E +EK + + A + N L+ + K AAV A+
Sbjct: 1338 KQAESQIAELQVKLAEIERARSELQEKCTKLQQEAENITNQLEEAELKASAAVKSASNME 1397
Query: 856 SSLYDYETVEE 866
S L + + + E
Sbjct: 1398 SQLTEAQQLLE 1408
Score = 53.5 bits (127), Expect = 1e-06
Identities = 57/226 (25%), Positives = 115/226 (50%), Gaps = 26/226 (11%)
Query: 471 QYDEDQHQAKLALYSKEQDERYETKAQEY--EEKIQSI--QAEIAELDAQME--QVRLEH 524
Q +E + +A A+ S E T+AQ+ EE Q + +++ +++++ E Q +LE
Sbjct: 1378 QLEEAELKASAAVKSASNMESQLTEAQQLLEEETRQKLGLSSKLRQIESEKEALQEQLEE 1437
Query: 525 EEKLKLKQVEKSQALLETNVKHINAKG----DLYKQTEEIKNQTISDKEDKEVAHQTVQS 580
+++ K + E+ A + T ++ I K DL K+ EE K + D E ++
Sbjct: 1438 DDEAK-RNYERKLAEVTTQMQEIKKKAEEDADLAKELEEGKKRLNKDIE-------ALER 1489
Query: 581 EIDELLLLKDEVAKENQEHESKVEELTAELDNKTSALNESLAKKDETNAEIQALEEEKA- 639
++ EL+ D + K ++ +S++E+ T EL+ + + + E L KK + +I L EEKA
Sbjct: 1490 QVKELIAQNDRLDKSKKKIQSELEDATIELEAQRTKVLE-LEKKQKNFDKI--LAEEKAI 1546
Query: 640 --RLEQEIKEAQELHQQNVSKIESIDNK--EYLPKVNEINTEISSL 681
++ QE A+ ++ +K+ S+ + E K+ ++ + +L
Sbjct: 1547 SEQIAQERDTAEREAREKETKVLSVSRELDEAFDKIEDLENKRKTL 1592
>Hs15313972 [Z] KOG0161 Myosin class II heavy chain
Length = 1647
Score = 60.5 bits (145), Expect = 1e-08
Identities = 64/314 (20%), Positives = 142/314 (44%), Gaps = 42/314 (13%)
Query: 473 DEDQHQAKLALYSKEQDE---RYETKAQEYEEKIQSIQAEIAELDAQMEQV--RLEHEE- 526
+ ++ +A+LA +E +E E++ +E EE+ Q +Q E ++ A ++ + +L+ EE
Sbjct: 576 EAEEMRARLAAKKQELEEILHDLESRVEEEEERNQILQNEKKKMQAHIQDLEEQLDEEEG 635
Query: 527 ------------KLKLKQVEKSQALLET-NVKHINAKGDLYKQTEEIKNQTISDKEDKEV 573
+ K+K++E+ LLE N K I K + + E +Q ++++E+K
Sbjct: 636 ARQKLQLEKVTAEAKIKKMEEEILLLEDQNSKFIKEKKLMEDRIAECSSQ-LAEEEEKAK 694
Query: 574 AHQTVQSEIDELLLLKDEVAKENQEHESKVEELTAELDNKTSALNESLAKKDETNAEIQA 633
++++ + ++ +E K+ ++ ++E+ +LD +T+ L + +A E A+I
Sbjct: 695 NLAKIRNKQEVMISDLEERLKKEEKTRQELEKAKRKLDGETTDLQDQIA---ELQAQIDE 751
Query: 634 LEEEKARLEQEIKEA------QELHQQNVSKIESIDNKEYLPKVNEINTEISSLLASLGL 687
L+ + A+ E+E++ A + LH+ N K+ +E ++ E+ + S AS
Sbjct: 752 LKLQLAKKEEELQGALARGDDETLHKNNALKVV----RELQAQIAELQEDFESEKASRNK 807
Query: 688 IQQEIANQKVEFSSVTXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXTEYEKQAEEAR 747
+++ + E ++ E +K EE
Sbjct: 808 AEKQKRDLSEELEALKTELEDTLDTTAAQQELRTKREQEVA---------ELKKALEEET 858
Query: 748 LKHEEELANLKQTH 761
HE ++ +++Q H
Sbjct: 859 KNHEAQIQDMRQRH 872
Score = 58.9 bits (141), Expect = 3e-08
Identities = 33/166 (19%), Positives = 94/166 (55%), Gaps = 5/166 (3%)
Query: 486 KEQDERYETKAQEYEEKIQSIQAEIAELDAQMEQVRLEHEEKLKLK--QVEKSQALLETN 543
++Q E T+ +E E+++Q+ + L+ M+ ++ + E L+ + Q E+ + LL
Sbjct: 1209 EQQVEEMRTQLEELEDELQATEDAKLRLEVNMQAMKAQFERDLQTRDEQNEEKKRLLIKQ 1268
Query: 544 VKHINAKGDLYKQTEEIKNQTISDKEDKEVAHQTVQSEIDELLLLKDEVAKENQEHESKV 603
V+ + A+ + ++ + ++ K+ E+ + ++++I+ +DEV K+ ++ ++++
Sbjct: 1269 VRELEAELEDERKQRAL---AVASKKKMEIDLKDLEAQIEAANKARDEVIKQLRKLQAQM 1325
Query: 604 EELTAELDNKTSALNESLAKKDETNAEIQALEEEKARLEQEIKEAQ 649
++ EL+ ++ +E A+ E+ ++++LE E +L++E+ ++
Sbjct: 1326 KDYQRELEEARASRDEIFAQSKESEKKLKSLEAEILQLQEELASSE 1371
Score = 55.5 bits (132), Expect = 4e-07
Identities = 44/219 (20%), Positives = 110/219 (50%), Gaps = 18/219 (8%)
Query: 488 QDERYETKAQEYEEKIQSIQAEIAELDAQMEQVRLEHEEKLKLKQVEKSQALLETNVKHI 547
Q R E + Q +E++ ++ + +++ ++E++ +H++ L+ K + Q ET
Sbjct: 517 QVTRQEEELQAKDEELLKVKEKQTKVEGELEEMERKHQQLLEEKNILAEQLQAET----- 571
Query: 548 NAKGDLYKQTEEIKNQTISDKEDKEVAHQTVQSEIDELLLLKDEVAKENQEHESKVEELT 607
+L+ + EE++ + + K++ E ++S ++E + E ++ ++ +++L
Sbjct: 572 ----ELFAEAEEMRARLAAKKQELEEILHDLESRVEEEEERNQILQNEKKKMQAHIQDLE 627
Query: 608 AELDNKTSALNESLAKKDETNAEIQALEEEKARLEQE----IKEAQELHQQNVSKIES-- 661
+LD + A + +K A+I+ +EEE LE + IKE ++L + +++ S
Sbjct: 628 EQLDEEEGARQKLQLEKVTAEAKIKKMEEEILLLEDQNSKFIKE-KKLMEDRIAECSSQL 686
Query: 662 IDNKEYLPKVNEINTEISSLLASL--GLIQQEIANQKVE 698
+ +E + +I + +++ L L ++E Q++E
Sbjct: 687 AEEEEKAKNLAKIRNKQEVMISDLEERLKKEEKTRQELE 725
Score = 52.4 bits (124), Expect = 3e-06
Identities = 52/229 (22%), Positives = 108/229 (46%), Gaps = 28/229 (12%)
Query: 449 EDPELIVRTQEGYVSKSVYDKLQYDEDQHQAKLALYSKEQ--DERYETKAQEYE--EKIQ 504
E L +++Q K V D L E +AK L + +R E KA Y+ EK +
Sbjct: 1034 EKQVLALQSQLADTKKKVDDDLGTIESLEEAKKKLLKDAEALSQRLEEKALAYDKLEKTK 1093
Query: 505 S-IQAEIAELDAQMEQVRLEHEEKLKLKQVEKSQALLETNVKHINAKGDLYKQTEEIKNQ 563
+ +Q E+ +L ++ R + L+ KQ + Q L E K I+A+ E +++
Sbjct: 1094 NRLQQELDDLTVDLDHQR-QVASNLEKKQKKFDQLLAEE--KSISAR------YAEERDR 1144
Query: 564 TISDKEDKEVAHQTVQSEIDELLLLKDEVAKENQEHESKVEELTAELDNKTSALNESLAK 623
++ +KE ++ ++E L K+E ++N++ + +E+L ++
Sbjct: 1145 AEAEAREKETKALSLARALEEALEAKEEFERQNKQLRADMEDL--------------MSS 1190
Query: 624 KDETNAEIQALEEEKARLEQEIKEAQELHQQNVSKIESIDNKEYLPKVN 672
KD+ + LE+ K LEQ+++E + ++ ++++ ++ + +VN
Sbjct: 1191 KDDVGKNVHELEKSKRALEQQVEEMRTQLEELEDELQATEDAKLRLEVN 1239
>YNL079c [Z] KOG1003 Actin filament-coating protein tropomyosin
Length = 199
Score = 60.1 bits (144), Expect = 1e-08
Identities = 46/189 (24%), Positives = 92/189 (48%), Gaps = 20/189 (10%)
Query: 486 KEQDERYETKAQEYEEKIQSIQAEIAELDAQMEQVRLEHE------EKLKL-----KQVE 534
K + E ++ K +E +EK + ++ E E + Q++ + ++++ EKL+ KQ E
Sbjct: 12 KLEAESWQEKYEELKEKNKDLEQENVEKENQIKSLTVKNQQLEDEIEKLEAGLSDSKQTE 71
Query: 535 KSQALLETNVKHINAKG-DLYKQTEEIKNQTISDKEDKEVAHQTVQSEIDELLLLKDEVA 593
+ E +K + K L ++ E+++ + K+ E +H +QS D +
Sbjct: 72 QDNVEKENQIKSLTVKNHQLEEEIEKLEAELAESKQLSEDSHH-LQSN-------NDNFS 123
Query: 594 KENQEHESKVEELTAELDNKTSALNESLAKKDETNAEIQALEEEKARLEQEIKEAQELHQ 653
K+NQ+ E +EE +L T L ES K D+ + ALEE++ E++ +E ++
Sbjct: 124 KKNQQLEEDLEESDTKLKETTEKLRESDLKADQLERRVAALEEQREEWERKNEELTVKYE 183
Query: 654 QNVSKIESI 662
+++ I
Sbjct: 184 DAKKELDEI 192
>Hs4557773 [Z] KOG0161 Myosin class II heavy chain
Length = 1935
Score = 59.7 bits (143), Expect = 2e-08
Identities = 52/182 (28%), Positives = 87/182 (47%), Gaps = 27/182 (14%)
Query: 486 KEQDERYETKAQEYEEKIQSIQAEIAELDAQM--EQVRLEHEEKLKLKQVEKSQALLETN 543
KE E+ E + +E EEK+ S+ E +L Q+ EQ L E+ + Q+ K++ LE
Sbjct: 860 KEALEKSEARRKELEEKMVSLLQEKNDLQLQVQAEQDNLADAEE-RCDQLIKNKIQLEAK 918
Query: 544 VKHINAKGDLYKQTEEIKNQTISDKEDKEVAHQTVQSEIDELLLLKDEVAKENQEHESKV 603
VK +N + + EE+ + + K E ++ +ID+L L +V KE E+KV
Sbjct: 919 VKEMNER---LEDEEEMNAELTAKKRKLEDECSELKRDIDDLELTLAKVEKEKHATENKV 975
Query: 604 EELTAELDNKTSALNESLAKKDETNAEIQALEEEKARLEQEIKEAQELHQQNVSKIESID 663
+ LT E+ L+E A+L +E K QE HQQ + +++ +
Sbjct: 976 KNLTEEM---------------------AGLDEIIAKLTKEKKALQEAHQQALDDLQAEE 1014
Query: 664 NK 665
+K
Sbjct: 1015 DK 1016
>Hs20558376 [Z] KOG0161 Myosin class II heavy chain
Length = 1937
Score = 59.7 bits (143), Expect = 2e-08
Identities = 52/212 (24%), Positives = 102/212 (47%), Gaps = 30/212 (14%)
Query: 484 YSKEQDE--RYETKAQEYEEKIQSIQAEIAELDAQME-QVRLEHEEKLKLKQVEKSQALL 540
+ K +DE + E K +E EEK+ ++ E +L Q++ + + + + +Q+ K++ L
Sbjct: 859 FQKTKDELAKSEAKRKELEEKMVTLLKEKNDLQLQVQSEADSLADAEERCEQLIKNKIQL 918
Query: 541 ETNVKHINAKGDLYKQTEEIKNQTISDKEDKEVAHQTVQSEIDELLLLKDEVAKENQEHE 600
E +K + + + + EEI + + K E ++ +ID+L L +V KE E
Sbjct: 919 EAKIKEVTERAE---EEEEINAELTAKKRKLEDECSELKKDIDDLELTLAKVEKEKHATE 975
Query: 601 SKVEELTAELDNKTSALNESLAKKDETNAEIQALEEEKARLEQEIKEAQELHQQNVSKIE 660
+KV+ LT E+ L+E A+L +E K QE HQQ + ++
Sbjct: 976 NKVKNLTEEM---------------------AGLDETIAKLSKEKKALQETHQQTLDDLQ 1014
Query: 661 SIDNKEYLPKVNEINTEISSLLASL-GLIQQE 691
+ ++K + + + T++ + L G ++QE
Sbjct: 1015 AEEDKVNI--LTKAKTKLEQQVDDLEGSLEQE 1044
Score = 55.8 bits (133), Expect = 3e-07
Identities = 48/238 (20%), Positives = 122/238 (51%), Gaps = 25/238 (10%)
Query: 474 EDQHQAKLALYSKEQDERYETKA--QEYEEKIQS---IQAEIAELDAQMEQVRLEHEEKL 528
E++ +AK AL Q R++ ++YEE+ + +Q +++ ++++ Q R ++E
Sbjct: 1323 EEETKAKNALAHALQSSRHDCDLLREQYEEEQEGKAELQRALSKANSEVAQWRTKYETDA 1382
Query: 529 KLKQVEKSQALLETNVKHINAKGDLYKQTEEIKNQTISDKEDKEVAHQTVQSEIDELLLL 588
+++++ L E K + + E + + S ++ K Q +Q+E+++L+L
Sbjct: 1383 ----IQRTEELEEAKKKLAQRLQEAEEHVEAVNAKCASLEKTK----QRLQNEVEDLML- 1433
Query: 589 KDEVAKENQEHESKVEELTAELDNKTSALNESLAKKDETNAEIQALEEEKARLEQEIKEA 648
+V + N + L + N L+E K +ET AE++A ++E L E+ +
Sbjct: 1434 --DVERSN----AACAALDKKQRNFDKVLSEWKQKYEETQAELEASQKESRSLSTELFKV 1487
Query: 649 QELHQQNVSKIESI--DNKEYLPKVNEINTEIS---SLLASLGLIQQEIANQKVEFSS 701
+ ++++++ ++E++ +NK +++++ +I+ + L I++++ +K E +
Sbjct: 1488 KNVYEESLDQLETLRRENKNLQQEISDLTEQIAEGGKQIHELEKIKKQVEQEKCEIQA 1545
>7292701_2 [S] KOG4415 Uncharacterized conserved protein
Length = 1643
Score = 59.7 bits (143), Expect = 2e-08
Identities = 64/282 (22%), Positives = 123/282 (42%), Gaps = 25/282 (8%)
Query: 418 RSKKPESSTKVAANAAAGTVVPGDDAPVATPEDPELIVRTQEGYVS-KSVYDKLQYDEDQ 476
++ ++ K A T+ + A ++ +L + +E + K +KL+ E +
Sbjct: 698 KTMSKDNKKKQKPGDAVATMTIDKEKEKAKEKELKLKEKEREAKLQEKEKEEKLKLKERE 757
Query: 477 HQAKLALYSKEQDERYETKAQEY---EEKIQSIQAE-------IAELDAQMEQVRLEHEE 526
++ K ++E+ + K +E EEKI+ Q E + E + + E EE
Sbjct: 758 ESLRMEREEKLKEEKIKEKEREEKLKEEKIKEKQREEKLKEEKLKEKEREERMKEKEREE 817
Query: 527 KLKLKQVEKSQALLETNVKHINAKGDLYK--QTEEIKNQTISDKEDKEVAHQTVQSEIDE 584
K K KQ + + L E +K + L + + E+IK + +K KE + + E +E
Sbjct: 818 KAKEKQ--REEKLREEKIKEKEREEKLKEKLREEKIKEKEKEEKLRKEREEKMREKEREE 875
Query: 585 LLLLKDEVAKENQEHESKVEELTAELDNKTSALNESLAKKDETNAEIQALEEEKAR---- 640
+ K+ V E + + + E+L E + K E L KK++ E + +EK R
Sbjct: 876 KIKEKERV--EKIKEKEREEKLKKEKEEKLKEKEELLKKKEKEEKEREEKLKEKERQEKL 933
Query: 641 ----LEQEIKEAQELHQQNVSKIESIDNKEYLPKVNEINTEI 678
E+++K E Q+ + E + KE K+ ++ E+
Sbjct: 934 KEKEREEKLKRETEERQREKEREEKLKEKERAEKLKDLEKEV 975
Score = 54.7 bits (130), Expect = 6e-07
Identities = 60/236 (25%), Positives = 111/236 (46%), Gaps = 17/236 (7%)
Query: 474 EDQHQAKLA---LYSKEQDERYETKAQEYEEKIQSIQAEIAELDAQMEQVRLEHEEKL-- 528
E Q + KL L KE++ER + K +E + K + + ++ E + ++ + +EKL
Sbjct: 789 EKQREEKLKEEKLKEKEREERMKEKEREEKAKEKQREEKLREEKIKEKEREEKLKEKLRE 848
Query: 529 -KLKQVEKSQALLETNVKHINAKGDLYKQTEEIKNQTISDKEDKEVAHQTVQSEIDELLL 587
K+K+ EK + L + + + K K E+ + + I +KE +E + + ++ E
Sbjct: 849 EKIKEKEKEEKLRKEREEKMREKEREEKIKEKERVEKIKEKEREEKLKKEKEEKLKEKEE 908
Query: 588 LKDEVAKENQEHESKVEELTAELDNKTSALNESLAKKDETNAEIQALEE---EKAR---- 640
L + KE +E E K++E + K E L ++ E + EE EK R
Sbjct: 909 LLKKKEKEEKEREEKLKEKERQEKLKEKEREEKLKRETEERQREKEREEKLKEKERAEKL 968
Query: 641 --LEQEIKEAQELHQQNVSKIESIDNKEYLPKVNEINTEISSLLASLGLIQQEIAN 694
LE+E+K +E +Q K + + KE K +++ + SL + LI ++N
Sbjct: 969 KDLEKEVK-LKEKEEQLKEKEKELKLKEKKEK-DKVKEKEKSLESEKLLISATVSN 1022
>SPAC688.11 [Z] KOG0980 Actin-binding protein SLA2/Huntingtin-interacting
protein Hip1
Length = 1092
Score = 59.3 bits (142), Expect = 2e-08
Identities = 58/260 (22%), Positives = 109/260 (41%), Gaps = 36/260 (13%)
Query: 478 QAKLALYSKEQDERYETKAQEYEEKIQSIQAEIAE---------------LDAQMEQVRL 522
QA+LA + ER AQ++++ +++IQ AE + Q + L
Sbjct: 358 QAQLAAQQAAEMERQRMAAQQHQQALEAIQMAQAEQQRIAQEQLAQQQFQMQTQGQLAEL 417
Query: 523 EHEEKLKLKQVEKSQALL------------ETNVKHINAKGDLYKQT---EEIKNQTISD 567
E + Q+E+S LL E + +N + +++ E +KNQ ++
Sbjct: 418 EQQLLATRGQLEQSNVLLNQYDARVRTLENELSQAGVNLQEQIHQNDDLIESLKNQILTW 477
Query: 568 KEDKEVAH----QTVQSEIDELLLLKDEVAKENQEHES--KVEELTAELDNKTSALNESL 621
K E Q Q +D L K K + E+ K E++ E+ NK L + +
Sbjct: 478 KNKYEALAKLYTQLRQEHLDLLSKYKQIQLKASSAQEAIDKKEKMEREMKNKNLELADMI 537
Query: 622 AKKDETNAEIQALEEEKARLEQEIKEAQELHQQNVSKIESIDNKEYLPKVNEINTEISSL 681
++D E++ + + ++ + L Q+ + +E + E ++ NTE++ L
Sbjct: 538 LERDRARHELETMHRSQRDKQESTERELRLLQEKAASLERNKSSEVSNLLSRYNTEVAHL 597
Query: 682 LASLGLIQQEIANQKVEFSS 701
+L +E+AN VE S
Sbjct: 598 EDALHSKDRELANLGVELKS 617
>Hs20542063 [Z] KOG0161 Myosin class II heavy chain
Length = 1939
Score = 59.3 bits (142), Expect = 2e-08
Identities = 52/182 (28%), Positives = 86/182 (46%), Gaps = 27/182 (14%)
Query: 486 KEQDERYETKAQEYEEKIQSIQAEIAELDAQM--EQVRLEHEEKLKLKQVEKSQALLETN 543
KE E+ E + +E EEK+ S+ E +L Q+ EQ L E+ + Q+ K++ LE
Sbjct: 862 KETLEKSEARRKELEEKMVSLLQEKNDLQLQVQAEQDNLNDAEE-RCDQLIKNKIQLEAK 920
Query: 544 VKHINAKGDLYKQTEEIKNQTISDKEDKEVAHQTVQSEIDELLLLKDEVAKENQEHESKV 603
VK +N + + EE+ + + K E ++ +ID+L L +V KE E+KV
Sbjct: 921 VKEMNER---LEDEEEMNAELTAKKRKLEDECSELKKDIDDLELTLAKVEKEKHATENKV 977
Query: 604 EELTAELDNKTSALNESLAKKDETNAEIQALEEEKARLEQEIKEAQELHQQNVSKIESID 663
+ LT E+ L+E A+L +E K QE HQQ + ++ +
Sbjct: 978 KNLTEEM---------------------AGLDEIIAKLTKEKKALQEAHQQALDDLQVEE 1016
Query: 664 NK 665
+K
Sbjct: 1017 DK 1018
Score = 52.4 bits (124), Expect = 3e-06
Identities = 50/252 (19%), Positives = 129/252 (50%), Gaps = 28/252 (11%)
Query: 475 DQHQAKLALYSKEQDERYETKAQEY---EEKIQSIQAEIAELDAQMEQVR--LEHEEKLK 529
D+ AKL K E ++ + E+K+ S+ +L+ Q++ + LE E+K++
Sbjct: 988 DEIIAKLTKEKKALQEAHQQALDDLQVEEDKVNSLSKSKVKLEQQVDDLEGSLEQEKKVR 1047
Query: 530 LKQVEKSQALLETNVKHINAKGDLYKQTEEIKNQTISDKEDKEVAHQTVQSEIDELLLLK 589
+ +E+++ LE ++K + + + + ++++ + K++ ++ Q + E +++L L
Sbjct: 1048 M-DLERAKRKLEGDLK-LTQESIMDLENDKLQLEEKLKKKEFDINQQNSKIEDEQVLAL- 1104
Query: 590 DEVAKENQEHESKVEELTAELDNKTSA------LNESLAKKDE------------TNAEI 631
++ K+ +E+++++EEL EL+ + +A L L+++ E T+ +I
Sbjct: 1105 -QLQKKLKENQARIEELEEELEAERTARAKVEKLRSDLSRELEEISERLEEAGGATSVQI 1163
Query: 632 QALEEEKARLEQEIKEAQELHQQNVSKIESIDNKEYLPKVNEINTEISSLLASLGLIQQE 691
+ ++ +A ++ ++ +E Q+ + ++ K++ V E+ +I +L +++E
Sbjct: 1164 EMNKKREAEFQKMRRDLEEATLQHEATAAAL-RKKHADSVAELGEQIDNLQRVKQKLEKE 1222
Query: 692 IANQKVEFSSVT 703
+ K+E VT
Sbjct: 1223 KSEFKLELDDVT 1234
>Hs12667788 [Z] KOG0161 Myosin class II heavy chain
Length = 1960
Score = 59.3 bits (142), Expect = 2e-08
Identities = 48/211 (22%), Positives = 100/211 (46%), Gaps = 19/211 (9%)
Query: 488 QDERYETKAQEYEEKIQSIQAEIAELDAQMEQVRLEHEEKLK-----LKQVEKSQALLET 542
Q E + QE ++++ E +AQ++++R +H + ++ L+Q ++ +A LE
Sbjct: 1158 QQELRSKREQEVNILKKTLEEEAKTHEAQIQEMRQKHSQAVEELAEQLEQTKRVKANLE- 1216
Query: 543 NVKHINAKGDLYKQTEEIKNQT---ISDKEDKEVAHQTVQSEIDELLLLKDEVAKENQEH 599
AK L + E+ N+ + K D E + V++++ EL + +E + E
Sbjct: 1217 -----KAKQTLENERGELANEVKVLLQGKGDSEHKRKKVEAQLQELQVKFNEGERVRTEL 1271
Query: 600 ESKVEELTAELDNKTSALNESLAKKDETNAEIQALEEEKARLEQEIKEAQELHQQNVSKI 659
KV +L ELDN T L++S +K + + ALE + ++ ++E +K+
Sbjct: 1272 ADKVTKLQVELDNVTGLLSQSDSKSSKLTKDFSALESQLQDTQELLQEENRQKLSLSTKL 1331
Query: 660 ESIDN-----KEYLPKVNEINTEISSLLASL 685
+ +++ +E L + E + +A+L
Sbjct: 1332 KQVEDEKNSFREQLEEEEEAKHNLEKQIATL 1362
Score = 57.8 bits (138), Expect = 7e-08
Identities = 40/195 (20%), Positives = 105/195 (53%), Gaps = 14/195 (7%)
Query: 462 VSKSVYDKLQYDEDQHQAKLALYSKEQDERYETKAQEYEEKIQSIQAEIAELDAQMEQVR 521
V KSV++ ++K AL ++Q E +T+ +E E+++Q+ + L+ ++ ++
Sbjct: 1516 VGKSVHEL-------EKSKRAL--EQQVEEMKTQLEELEDELQATEDAKLRLEVNLQAMK 1566
Query: 522 LEHEEKLKLK--QVEKSQALLETNVKHINAKGDLYKQTEEIKNQTISDKEDKEVAHQTVQ 579
+ E L+ + Q E+ + L V+ + A+ + + ++ ++ ++ E+ + ++
Sbjct: 1567 AQFERDLQGRDEQSEEKKKQLVRQVREMEAE---LEDERKQRSMAVAARKKLEMDLKDLE 1623
Query: 580 SEIDELLLLKDEVAKENQEHESKVEELTAELDNKTSALNESLAKKDETNAEIQALEEEKA 639
+ ID +DE K+ ++ ++++++ ELD+ ++ E LA+ E +++++E E
Sbjct: 1624 AHIDSANKNRDEAIKQLRKLQAQMKDCMRELDDTRASREEILAQAKENEKKLKSMEAEMI 1683
Query: 640 RLEQEIKEAQELHQQ 654
+L++E+ A+ +Q
Sbjct: 1684 QLQEELAAAERAKRQ 1698
Score = 52.8 bits (125), Expect = 2e-06
Identities = 59/253 (23%), Positives = 115/253 (45%), Gaps = 43/253 (16%)
Query: 468 DKLQYDEDQHQAKLALYSKEQDERYETKAQEYEEKIQSIQAEIAELDAQMEQVRLEHEEK 527
++L+ +E Q Q ++ + E + + ++I +QA+IAEL +M+ + E E +
Sbjct: 1034 ERLRREEKQRQEL-----EKTRRKLEGDSTDLSDQIAELQAQIAEL--KMQLAKKEEELQ 1086
Query: 528 LKLKQVE-----KSQAL-----LETNVKHINA---------------KGDLYKQTEEIKN 562
L +VE K+ AL LE+ + + K DL ++ E +K
Sbjct: 1087 AALARVEEEAAQKNMALKKIRELESQISELQEDLESERASRNKAEKQKRDLGEELEALKT 1146
Query: 563 QTISDKEDKEVAHQTVQSEID-ELLLLKDEVAKENQEHESKVEELTAELDNKTSALNESL 621
+ + D D A Q ++S+ + E+ +LK + +E + HE++++E+ + L E L
Sbjct: 1147 E-LEDTLDSTAAQQELRSKREQEVNILKKTLEEEAKTHEAQIQEMRQKHSQAVEELAEQL 1205
Query: 622 AKKDETNAEI----QALEEEKARLEQEIKEAQELHQQNVSKIESIDN--KEYLPKVNE-- 673
+ A + Q LE E+ L E+K + + K + ++ +E K NE
Sbjct: 1206 EQTKRVKANLEKAKQTLENERGELANEVKVLLQGKGDSEHKRKKVEAQLQELQVKFNEGE 1265
Query: 674 -INTEISSLLASL 685
+ TE++ + L
Sbjct: 1266 RVRTELADKVTKL 1278
>SPAC1486.04c [S] KOG4674 Uncharacterized conserved coiled-coil protein
Length = 1727
Score = 58.9 bits (141), Expect = 3e-08
Identities = 79/359 (22%), Positives = 151/359 (42%), Gaps = 54/359 (15%)
Query: 374 EAISPPPDINSAPRVPFTP--SGANKXXXXXXXXXXXXXXLFALFKRSKKP-ESSTKVAA 430
E SP PD++S ++ + + + LF K+ K+ ESS +V A
Sbjct: 1145 EITSPSPDLDSVMKLGLSDLQNHVKRISKEMEIISCQRQLLFLENKKLKRTVESSNRVIA 1204
Query: 431 NAAAGTVVPGDDAPVATPEDPELIVRTQEGYVSKSVYDKLQYDEDQHQAKLALYSKEQDE 490
+ G T +D + T E +S Y + ++ L +E E
Sbjct: 1205 DLQRGI----------TEKD---VSSTSESVGERSNYLNMVALLNESNKSL----RENLE 1247
Query: 491 RYETKAQEYEEKIQSIQAEIAELDAQMEQVRLE-HEEKLKLKQVEKSQALLETNVKHI-- 547
R E E EKI++++ ++A EQ+ + EK +K++E S + + + I
Sbjct: 1248 RNEEVITELREKIETLKTDLANFRLNKEQLESQLQTEKAAVKKLENSNEEYKRHNQEILL 1307
Query: 548 --NAKGDLYKQTEEIKNQTIS-----DKEDKEVAHQTVQSEIDELLLLKDEVAKENQEHE 600
N+ +KN+ +S ++ ++E+ H ++SE++ + +++ E +++
Sbjct: 1308 SLNSSTSTSSDASRLKNELVSKENLIEELNQEIGH--LKSELETVKSKSEDLENERAQNQ 1365
Query: 601 SKVEELTAELDNKTSA----------LNESLAKKDETNAEIQALEEEKARLEQEIKEAQE 650
SK+E+L EL N A +N+SL K ++ Q L ++ + LE ++ E +
Sbjct: 1366 SKIEQL--ELKNTKLAAAWRTKYEQVVNKSLEKHNQIR---QQLSQKTSELEAKVAECHQ 1420
Query: 651 LHQQ-------NVSKIESIDNKEYLPKVNEINTEISSLLASLGLIQQEIANQKVEFSSV 702
L++Q + +S + L + N E+SS L I + K E V
Sbjct: 1421 LNEQLNKPSATPTATTQSEPSTVSLEEFNSTKEELSSTQRKLSEIMDILNTTKEELEKV 1479
>Hs7669506 [Z] KOG0161 Myosin class II heavy chain
Length = 1939
Score = 58.9 bits (141), Expect = 3e-08
Identities = 46/182 (25%), Positives = 86/182 (46%), Gaps = 25/182 (13%)
Query: 485 SKEQDERYETKAQEYEEKIQSIQAEIAELDAQME-QVRLEHEEKLKLKQVEKSQALLETN 543
+KE+ + E K +E EEK+ ++ E +L Q++ + + + + Q+ K++ LE
Sbjct: 863 TKEELAKTEAKRKELEEKMVTLMQEKNDLQLQVQAEADSLADAEERCDQLIKTKIQLEAK 922
Query: 544 VKHINAKGDLYKQTEEIKNQTISDKEDKEVAHQTVQSEIDELLLLKDEVAKENQEHESKV 603
+K + + + EEI + + K E ++ +ID+L L +V KE E+KV
Sbjct: 923 IKEVTERAE---DEEEINAELTAKKRKLEDECSELKKDIDDLELTLAKVEKEKHATENKV 979
Query: 604 EELTAELDNKTSALNESLAKKDETNAEIQALEEEKARLEQEIKEAQELHQQNVSKIESID 663
+ LT E+ L+E A+L +E K QE HQQ + +++ +
Sbjct: 980 KNLTEEM---------------------AGLDETIAKLTKEKKALQEAHQQTLDDLQAEE 1018
Query: 664 NK 665
+K
Sbjct: 1019 DK 1020
Score = 54.7 bits (130), Expect = 6e-07
Identities = 50/239 (20%), Positives = 118/239 (48%), Gaps = 27/239 (11%)
Query: 474 EDQHQAKLALYSKEQDERYETKA--QEYEEKIQSIQAEIAELDAQMEQVRLEHEEKLKLK 531
E++ +AK AL Q R++ ++YEE+ Q +AE+ ++ + K +
Sbjct: 1324 EEEIKAKSALAHALQSSRHDCDLLREQYEEE-QEAKAELQRAMSKANSEVAQWRTKYETD 1382
Query: 532 QVEKSQALLETNVKHINAKGDLYKQTEEIKNQTISDKEDKEVAHQTVQSEIDELLLLKDE 591
+++++ L E K D + E + + S ++ K Q +Q+E+++L++ +
Sbjct: 1383 AIQRTEELEEAKKKLAQRLQDAEEHVEAVNAKCASLEKTK----QRLQNEVEDLMI---D 1435
Query: 592 VAKENQEHESKVEELTAELDNKTSALNESLA----KKDETNAEIQALEEEKARLEQEIKE 647
V + N A LD K ++ LA K +ET+AE++A ++E L E+ +
Sbjct: 1436 VERTNAA--------CAALDKKQRNFDKILAEWKQKCEETHAELEASQKESRSLSTELFK 1487
Query: 648 AQELHQQNVSKIESI--DNKEYLPKVNEINTEIS---SLLASLGLIQQEIANQKVEFSS 701
+ +++++ ++E++ +NK +++++ +I+ + L I++++ +K E +
Sbjct: 1488 IKNAYEESLDQLETLKRENKNLQQEISDLTEQIAEGGKRIHELEKIKKQVEQEKSELQA 1546
Score = 51.2 bits (121), Expect = 7e-06
Identities = 57/248 (22%), Positives = 108/248 (42%), Gaps = 22/248 (8%)
Query: 468 DKLQYDEDQHQAKL---ALYSKEQDERYETKAQEYEEKIQSIQAEIAELDAQMEQVRLEH 524
DK Q DE + + L SK +DE + + ++KI+ +QA I EL+ ++E R
Sbjct: 1076 DKQQLDEKLKKKEFEMSGLQSKIEDE--QALGMQLQKKIKELQARIEELEEEIEAERASR 1133
Query: 525 EEKLKLKQVEKSQALLETNVKHINAKGDLYKQTEEIKNQTIS-DKEDKEVAHQTVQSEID 583
K + ++ + S+ L E + + A G Q E K + K +++ T+Q E
Sbjct: 1134 A-KAEKQRSDLSRELEEISERLEEAGGATSAQIEMNKKREAEFQKMRRDLEEATLQHEAT 1192
Query: 584 ELLLLK-------------DEVAKENQEHESKVEELTAELDNKTSALNESLAKKDETNAE 630
L K D + + Q+ E + E+ E+D+ S + K
Sbjct: 1193 AATLRKKHADSVAELGEQIDNLQRVKQKLEKEKSEMKMEIDDLASNMETVSKAKGNLEKM 1252
Query: 631 IQALEEEKARLEQEIKEAQELHQQNVSKIESI--DNKEYLPKVNEINTEISSLLASLGLI 688
+ALE++ + ++ + +E Q L ++ + ++ EY +++E +T +S L
Sbjct: 1253 CRALEDQLSEIKTKEEEQQRLINDLTAQRARLQTESGEYSRQLDEKDTLVSQLSRGKQAF 1312
Query: 689 QQEIANQK 696
Q+I K
Sbjct: 1313 TQQIEELK 1320
>Hs19923140 [Z] KOG4280 Kinesin-like protein
Length = 793
Score = 58.9 bits (141), Expect = 3e-08
Identities = 64/266 (24%), Positives = 122/266 (45%), Gaps = 37/266 (13%)
Query: 415 LFKRSKKPESSTKVAANAAAGTVVPGDDAPVATPEDPELIVRTQEGYVSKSVYDKLQYDE 474
L KR ++ S K A +A P PE P + E +V++ D +
Sbjct: 400 LGKRPRRKSSRRKKAVSA-----------PPGYPEGPVI-----EAWVAEEEDD----NN 439
Query: 475 DQHQAKLALYSKEQDERYETKAQEYEEKIQSIQAEIAE---LDAQMEQVRLEHEEKL--K 529
+ H+ + ++ E QE +E+++ +A I + L ++ +Q LE +EK+
Sbjct: 440 NNHRPPQPILESALEKNMENYLQEQKERLEEEKAAIQDDRSLVSEEKQKLLEEKEKMLED 499
Query: 530 LKQVEKSQALLETNVKHINAK-----GDLYKQTEEIKNQTISDKEDKEVAHQTVQS-EID 583
L++ +++ LL K + +K ++ T E Q + + + +E+A Q + E+
Sbjct: 500 LRREQQATELLAAKYKAMESKLLIGGRNIMDHTNE--QQKMLELKRQEIAEQKRREREMQ 557
Query: 584 ELLLLKDEVAKENQEHESKVEELTAELDNKTSALNESLAKKDETNAEIQALEEEKARLEQ 643
+ ++L+DE E E L E++ KT L + AK AEIQ +E R+ Q
Sbjct: 558 QEMMLRDE---ETMELRGTYTSLQQEVEVKTKKLKKLYAKLQAVKAEIQDQHDEYIRVRQ 614
Query: 644 EIKEAQELHQQNVSKIESIDNKEYLP 669
+++EAQ Q K++ + + ++P
Sbjct: 615 DLEEAQN-EQTRELKLKYLIIENFIP 639
>Hs11024712 [Z] KOG0161 Myosin class II heavy chain
Length = 1939
Score = 58.9 bits (141), Expect = 3e-08
Identities = 51/209 (24%), Positives = 98/209 (46%), Gaps = 28/209 (13%)
Query: 485 SKEQDERYETKAQEYEEKIQSIQAEIAELDAQME-QVRLEHEEKLKLKQVEKSQALLETN 543
+KE+ + E K +E EEK+ ++ E +L Q++ + + + + Q+ K++ LE
Sbjct: 863 TKEELAKTEAKRKELEEKMVTLMQEKNDLQLQVQAEADALADAEERCDQLIKTKIQLEAK 922
Query: 544 VKHINAKGDLYKQTEEIKNQTISDKEDKEVAHQTVQSEIDELLLLKDEVAKENQEHESKV 603
+K + + + EEI + + K E ++ +ID+L L +V KE E+KV
Sbjct: 923 IKEVTERAE---DEEEINAELTAKKRKLEDECSELKKDIDDLELTLAKVEKEKHATENKV 979
Query: 604 EELTAELDNKTSALNESLAKKDETNAEIQALEEEKARLEQEIKEAQELHQQNVSKIESID 663
+ LT E+ L+E A+L +E K QE HQQ + ++ +
Sbjct: 980 KNLTEEM---------------------AGLDETIAKLTKEKKALQEAHQQTLDDLQMEE 1018
Query: 664 NKEYLPKVNEINTEISSLLASL-GLIQQE 691
+K + + + T++ + L G ++QE
Sbjct: 1019 DK--VNTLTKAKTKLEQQVDDLEGSLEQE 1045
Score = 53.1 bits (126), Expect = 2e-06
Identities = 68/318 (21%), Positives = 131/318 (40%), Gaps = 51/318 (16%)
Query: 468 DKLQYDEDQHQAKLALYSKEQDERYETKAQ------EYEEKIQSIQAEIAELDAQMEQVR 521
D+L + Q +AK+ ++ ++ E A+ + E++ ++ +I +L+ + +V
Sbjct: 910 DQLIKTKIQLEAKIKEVTERAEDEEEINAELTAKKRKLEDECSELKKDIDDLELTLAKVE 969
Query: 522 LE-HEEKLKLKQVEKSQALLETNVKHINAKGDLYKQTEEIKNQTISD---KEDK----EV 573
E H + K+K + + A L+ + + + K +E QT+ D +EDK
Sbjct: 970 KEKHATENKVKNLTEEMAGLDETIAKLTKEK---KALQEAHQQTLDDLQMEEDKVNTLTK 1026
Query: 574 AHQTVQSEIDEL---------LLLKDEVAKENQEHESKV-EELTAELDNKTSALNESLAK 623
A ++ ++D+L L + E AK E + K+ +E T + +N LNE L K
Sbjct: 1027 AKTKLEQQVDDLEGSLEQEKKLCMDLERAKRKLEGDLKLAQESTMDTENDKQQLNEKLKK 1086
Query: 624 KDETNAEIQALEEEKARLEQEIKEAQELHQQNVSKIESIDNKEYLPKVNEINTEISSLLA 683
K E E + L+ +I++ Q L Q KI KE ++ E+ EI + A
Sbjct: 1087 K----------EFEMSNLQGKIEDEQALAMQLQKKI-----KELQARIEELEEEIEAERA 1131
Query: 684 SLGLIQQEIANQKVEFSSVTXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXTEYEKQA 743
S +++ ++ E ++ + +
Sbjct: 1132 SRAKAEKQRSDLSRELEEIS---------ERLEEAGGATSAQIELNKKREAEFQKMRRDL 1182
Query: 744 EEARLKHEEELANLKQTH 761
EE+ L+HE A L++ H
Sbjct: 1183 EESTLQHEATAAALRKKH 1200
Score = 50.8 bits (120), Expect = 9e-06
Identities = 46/238 (19%), Positives = 121/238 (50%), Gaps = 25/238 (10%)
Query: 474 EDQHQAKLALYSKEQDERYETKA--QEYEEKIQS---IQAEIAELDAQMEQVRLEHEEKL 528
E++ +AK L Q R++ ++YEE+ ++ +Q +++ ++++ Q R ++E
Sbjct: 1324 EEETKAKSTLAHALQSARHDCDLLREQYEEEQEAKAELQRGMSKANSEVAQWRTKYETDA 1383
Query: 529 KLKQVEKSQALLETNVKHINAKGDLYKQTEEIKNQTISDKEDKEVAHQTVQSEIDELLLL 588
+++++ L E K D + E + ++ S ++ K Q +Q+E+++L++
Sbjct: 1384 ----IQRTEELEEAKKKLAQRLQDAEEHVEAVNSKCASLEKTK----QRLQNEVEDLMI- 1434
Query: 589 KDEVAKENQEHESKVEELTAELDNKTSALNESLAKKDETNAEIQALEEEKARLEQEIKEA 648
+V + N + L + N L E K +ET AE++A ++E L E+ +
Sbjct: 1435 --DVERSN----AACIALDKKQRNFDKVLAEWKQKYEETQAELEASQKESRSLSTELFKV 1488
Query: 649 QELHQQNVSKIESI--DNKEYLPKVNEINTEIS---SLLASLGLIQQEIANQKVEFSS 701
+ +++++ +E++ +NK +++++ +I+ + L +++++ ++K E +
Sbjct: 1489 KNAYEESLDHLETLKRENKNLQQEISDLTEQIAEGGKHIHELEKVKKQLDHEKSELQT 1546
>Hs4505301 [Z] KOG0161 Myosin class II heavy chain
Length = 1937
Score = 58.5 bits (140), Expect = 4e-08
Identities = 51/212 (24%), Positives = 102/212 (48%), Gaps = 30/212 (14%)
Query: 484 YSKEQDE--RYETKAQEYEEKIQSIQAEIAELDAQME-QVRLEHEEKLKLKQVEKSQALL 540
+ K +DE + E K +E EEK+ ++ E +L Q++ + + + + +Q+ K++ L
Sbjct: 859 FQKTKDELAKSEAKRKELEEKMVTLLKEKNDLQLQVQSEADSLADAEERCEQLIKNKIQL 918
Query: 541 ETNVKHINAKGDLYKQTEEIKNQTISDKEDKEVAHQTVQSEIDELLLLKDEVAKENQEHE 600
E +K + + + + EEI + + K E ++ +ID+L L +V K+ E
Sbjct: 919 EAKIKEVTERAE---EEEEINAELTAKKRKLEDECSELKKDIDDLELTLAKVEKQKHATE 975
Query: 601 SKVEELTAELDNKTSALNESLAKKDETNAEIQALEEEKARLEQEIKEAQELHQQNVSKIE 660
+KV+ LT E+ L+E A+L +E K QE HQQ + ++
Sbjct: 976 NKVKNLTEEM---------------------AGLDETIAKLSKEKKALQETHQQTLDDLQ 1014
Query: 661 SIDNKEYLPKVNEINTEISSLLASL-GLIQQE 691
+ ++K + + + T++ + L G ++QE
Sbjct: 1015 AEEDKVNI--LTKAKTKLEQQVDDLEGSLEQE 1044
Score = 52.4 bits (124), Expect = 3e-06
Identities = 47/238 (19%), Positives = 121/238 (50%), Gaps = 25/238 (10%)
Query: 474 EDQHQAKLALYSKEQDERYETKA--QEYEEKIQS---IQAEIAELDAQMEQVRLEHEEKL 528
E++ +AK AL Q R++ ++YEE+ + +Q +++ ++++ Q R ++E
Sbjct: 1323 EEETKAKNALAHALQSSRHDCDLLREQYEEEQEGKAELQRALSKANSEVAQWRTKYETDA 1382
Query: 529 KLKQVEKSQALLETNVKHINAKGDLYKQTEEIKNQTISDKEDKEVAHQTVQSEIDELLLL 588
+++++ L E K + + E + + S ++ K Q +Q+E+++L+L
Sbjct: 1383 ----IQRTEELEEAKKKLAQRLQEAEEHVEAVNAKCASLEKTK----QRLQNEVEDLML- 1433
Query: 589 KDEVAKENQEHESKVEELTAELDNKTSALNESLAKKDETNAEIQALEEEKARLEQEIKEA 648
+V + N + L + N L+E K +ET AE++A ++E L E+ +
Sbjct: 1434 --DVERSN----AACAALDKKQRNFDKVLSEWKQKYEETQAELEASQKESRSLSTELFKV 1487
Query: 649 QELHQQNVSKIESI--DNKEYLPKVNEINTEIS---SLLASLGLIQQEIANQKVEFSS 701
+ ++++++ ++E++ +K +++++ +I+ + L I++++ +K E +
Sbjct: 1488 KNVYEESLDQLETLRRAHKNLQQEISDLTEQIAEGGKQIHELEKIKKQVEQEKCEIQA 1545
>SPAC1556.01c [L] KOG0962 DNA repair protein RAD50 ABC-type ATPase/SMC
superfamily
Length = 658
Score = 58.2 bits (139), Expect = 6e-08
Identities = 55/213 (25%), Positives = 105/213 (48%), Gaps = 23/213 (10%)
Query: 478 QAKLALY--SKEQDERYETKAQEYEEKIQSIQAEIAELDAQMEQVRLEHEEKLKLKQVEK 535
QA L Y KE+ E+ E + E ++I I++++ ELD ++ + +E K + +
Sbjct: 205 QATLTHYRSDKERAEKIELRVHESLKRISCIRSKVEELDQEITETARLQDELFKSTEEYE 264
Query: 536 SQALLETNVKHINAKGDLYKQT-EEIKNQ-TISDK--EDKEVAHQTVQSEIDELLLLKDE 591
Q + ++H+ ++ D+ T ++K+Q TI+D+ ED E H ++ E + E
Sbjct: 265 QQMI---TIRHLESQSDIINTTINDLKSQMTITDESSEDLEKLHSNFAEKVKE----EQE 317
Query: 592 VAKENQEHESKVEELTAELDNKTSALNESLAKKDETNAEIQALEEEKARLEQEIKEAQEL 651
+ K ++ S +E L L ++ L + + EI++LE+ K + I E +
Sbjct: 318 LYKSLEKKRSDLESL---LKSRRELLEKLTGDLGKIQGEIESLEKLKVKKSTMINEI--V 372
Query: 652 HQQNVSKIES----IDNKEYLPKVNEINTEISS 680
H+ N+++I + +Y VN+ N EISS
Sbjct: 373 HRYNINEINEEGIMTEVSKYASLVNK-NYEISS 404
>CE09349 [Z] KOG0161 Myosin class II heavy chain
Length = 1963
Score = 57.8 bits (138), Expect = 7e-08
Identities = 58/231 (25%), Positives = 111/231 (47%), Gaps = 28/231 (12%)
Query: 464 KSVYDKLQYDEDQHQAKLALYSKEQDERYETKAQEYEEKIQSIQAEIAELDAQMEQ---- 519
+++ KLQ Q++++ +E + +++++ K +Q E+ EL ++++
Sbjct: 1107 QALVSKLQRQIKDGQSRISELEEELENERQSRSKADRAK-SDLQRELEELGEKLDEQGGA 1165
Query: 520 --VRLEHEEKLKLKQVEKSQALLETNVKHINAKGDLYKQTEEIKNQTISDKEDKEVAHQT 577
++E +K + + + + L E N+ H N G L K K VA T
Sbjct: 1166 TAAQVEVNKKREAELAKLRRDLEEANMNHENQLGGLRK------------KHTDAVAELT 1213
Query: 578 VQSEIDELLLLKDEVAKENQEHESKVEELTAELDNKTSAL--NESLAKKDETN-AEIQAL 634
Q +D+L K +V K+ + E+L A+LD +TS NE LAK+ E E+Q+
Sbjct: 1214 DQ--LDQLNKAKAKVEKDKAQAVRDAEDLAAQLDQETSGKLNNEKLAKQFELQLTELQSK 1271
Query: 635 EEEKARLEQEIKEAQ-ELHQQNVSKIESIDNKEYLPKVNEINTEISSLLAS 684
+E++R Q+ + LH +N + +++ E +VN++ T + S L S
Sbjct: 1272 ADEQSRQLQDFTSLKGRLHSENGDLVRQLEDAE--SQVNQL-TRLKSQLTS 1319
Score = 52.0 bits (123), Expect = 4e-06
Identities = 53/225 (23%), Positives = 109/225 (47%), Gaps = 36/225 (16%)
Query: 469 KLQYDEDQHQAKLALYSKEQDERYETKAQEYEEKIQSIQAEIAELDAQMEQVRLEHEEKL 528
+ Q + Q ++++ +E++E +E + + ++S+QA + E +A+ + L ++KL
Sbjct: 1569 RAQVEVSQIRSEIEKRIQEKEEEFENTRKNHARALESMQASL-ETEAKGKAELLRIKKKL 1627
Query: 529 KLKQVEKSQALLETNVKHINAKGDLYKQTEEIKNQTISDKEDKEVAHQT----------- 577
+ E AL N + +A+ +L + E+++ + +E++ T
Sbjct: 1628 EGDINELEIALDHANKANADAQKNLKRYQEQVRELQLQVEEEQRNGADTREQFFNAEKRA 1687
Query: 578 --VQSEIDELLLLKD--EVAKENQEHES-----KVEELTAELDNKTSA-------LNESL 621
+QSE +ELL+ + E A++ E+E+ + E A++ + TSA +
Sbjct: 1688 TLLQSEKEELLVANEAAERARKQAEYEAADARDQANEANAQVSSLTSAKRKLEGEIQAIH 1747
Query: 622 AKKDETNAEIQALEE-------EKARLEQEIKEAQELHQQNVSKI 659
A DET E +A EE + RL +E+++ QE H Q+V ++
Sbjct: 1748 ADLDETLNEYKAAEERSKKAIADATRLAEELRQEQE-HSQHVDRL 1791
>7298379 [ZR] KOG4568 Cytoskeleton-associated protein and related proteins
Length = 1690
Score = 57.8 bits (138), Expect = 7e-08
Identities = 57/241 (23%), Positives = 113/241 (46%), Gaps = 34/241 (14%)
Query: 465 SVYDKLQYDEDQHQAKLALYSKEQDERYETKAQEYEEKIQSIQAEIAELDAQMEQVRLEH 524
+V + LQ ++ + L+ E D ++ EK+ I+ E+ E Q+++ + +
Sbjct: 1136 TVLEVLQAEKSETNHIFELFEMEAD----MNSERLIEKVTGIKEELKETHLQLDERQKKF 1191
Query: 525 EE-KLKLKQVEKSQALLETNVKHINAKGDLYKQTEEIKNQTISDKEDKEVAHQTVQSEID 583
EE + KLKQ ++S+ L+ + K +Q+ + ++ KE
Sbjct: 1192 EELEEKLKQAQQSEQKLQQESQTSKEKLTEIQQSLQELQDSVKQKE-------------- 1237
Query: 584 ELLLLKDEVAKEN----QEHESKVEELTAELDNKTSALNESLAKKDETNAEIQALEEEKA 639
EL+ +E +E+ + +K+ E +L+NKTS L E+ + E+ + + L+EE A
Sbjct: 1238 ELVQNLEEKVRESSSIIEAQNTKLNESNVQLENKTSCLKETQDQLLESQKKEKQLQEEAA 1297
Query: 640 RLEQEIKEAQELHQQNVSKIESIDNKEYLPKVNEINTEISSLL--ASLGLIQQEIANQKV 697
+L E+++ QE + D K+ L KV E+ + L A+ L Q+ N+++
Sbjct: 1298 KLSGELQQVQEANG---------DIKDSLVKVEELVKVLEEKLQAATSQLDAQQATNKEL 1348
Query: 698 E 698
+
Sbjct: 1349 Q 1349
Score = 53.9 bits (128), Expect = 1e-06
Identities = 59/255 (23%), Positives = 114/255 (44%), Gaps = 25/255 (9%)
Query: 442 DAPVATPED-PELIVRTQEGYVSKSVYDKLQYDEDQHQAKLALYSKEQDERYETKAQEYE 500
DA AT ++ EL+V++QE LQ + KL + E E Q+ E
Sbjct: 1339 DAQQATNKELQELLVKSQENE------GNLQGESLAVTEKLQQLEQANGELKEALCQK-E 1391
Query: 501 EKIQSIQAEIAELDAQMEQVRLEHEE-KLKLKQVEKSQALLETNVKHINAKGDLYKQTEE 559
++ +Q ++ E + +E + H E + KL+Q ++ + L+ + + KQ E
Sbjct: 1392 NGLKELQGKLDESNTVLESQKKSHNEIQDKLEQAQQKERTLQEETSKLAEQLSQLKQANE 1451
Query: 560 IKNQTISDKE---------DKEVA-HQTVQSEIDELLLLKDEVAKENQEHESKVEELTAE 609
+++ K+ D ++A +Q V E+D+ +K + ++ Q ++V EL
Sbjct: 1452 ELQKSLQQKQLLLEKGNEFDTQLAEYQKVIDEMDDAASVKSALLEQLQ---NRVAELETA 1508
Query: 610 LDNKTSALNESLAKKDETNAEIQALEEEKARLEQEIKEAQELHQQNVSK---IESIDNKE 666
L A + + E ++++LE EK+R +K K +ES+D +
Sbjct: 1509 LRQANDAQKTAYLETKELRRQLESLELEKSREVLSLKAQMNGASSRSGKGDEVESLDIET 1568
Query: 667 YLPKVNEINTEISSL 681
L K+N +N+ I+ +
Sbjct: 1569 SLAKINFLNSIIADM 1583
Score = 51.2 bits (121), Expect = 7e-06
Identities = 55/239 (23%), Positives = 114/239 (47%), Gaps = 23/239 (9%)
Query: 469 KLQYDEDQHQAKLALYSKEQDERYETKAQEYEEKIQSIQAEIAELDAQMEQVRLEHEEKL 528
KL Q + K + + QD+ E++ +E + +Q E A+L +++QV+ + +
Sbjct: 1260 KLNESNVQLENKTSCLKETQDQLLESQKKE-----KQLQEEAAKLSGELQQVQEANGD-- 1312
Query: 529 KLKQVEKSQALLETNVKHINAKGDLYKQTEEIKNQTISDKEDKEVAHQTVQSEIDELLLL 588
++ S +E VK + K L T ++ Q ++KE +E+ V+S+ +E L
Sbjct: 1313 ----IKDSLVKVEELVKVLEEK--LQAATSQLDAQQATNKELQELL---VKSQENEGNLQ 1363
Query: 589 KDEVA--KENQEHESKVEELTAELDNKTSALNESLAKKDETNAEIQALEEEKARLEQEIK 646
+ +A ++ Q+ E EL L K + L E K DE+N +++ ++ ++ +++
Sbjct: 1364 GESLAVTEKLQQLEQANGELKEALCQKENGLKELQGKLDESNTVLESQKKSHNEIQDKLE 1423
Query: 647 EAQELHQQNVSKIESIDNKEYLPKVNEINTEISSLLASLGLIQQ---EIANQKVEFSSV 702
+AQ+ ++ + E+ E L ++ + N E+ L L+ + E Q E+ V
Sbjct: 1424 QAQQ--KERTLQEETSKLAEQLSQLKQANEELQKSLQQKQLLLEKGNEFDTQLAEYQKV 1480
>YIL138c [Z] KOG1003 Actin filament-coating protein tropomyosin
Length = 161
Score = 57.4 bits (137), Expect = 9e-08
Identities = 40/169 (23%), Positives = 85/169 (49%), Gaps = 15/169 (8%)
Query: 497 QEYEEKIQSIQAEIAELDAQMEQVRLEHEEKLKLKQVEKSQALLETNVKHINAKGD-LYK 555
++ +EK+ S++ E + E++R + LK++E+S E +K ++AK + L
Sbjct: 2 EKIKEKLNSLKLESESWQEKYEELREQ------LKELEQSNTEKENEIKSLSAKNEQLDS 55
Query: 556 QTEEIKNQTISDKEDKEVAHQTVQSEIDELLLLKDEVAKENQEHESKVEELTAELDNKTS 615
+ E++++Q K+ E + + L + K+NQ+ E ++E+ A+L
Sbjct: 56 EVEKLESQLSDTKQLAE--------DSNNLRSNNENYTKKNQDLEQQLEDSEAKLKEAMD 107
Query: 616 ALNESLAKKDETNAEIQALEEEKARLEQEIKEAQELHQQNVSKIESIDN 664
L E+ ++ I ALEEE+ E++ +E Q +++ +++ I N
Sbjct: 108 KLKEADLNSEQMGRRIVALEEERDEWEKKCEEFQSKYEEAQKELDEIAN 156
>CE04618 [Z] KOG0161 Myosin class II heavy chain
Length = 1956
Score = 57.4 bits (137), Expect = 9e-08
Identities = 58/269 (21%), Positives = 122/269 (44%), Gaps = 21/269 (7%)
Query: 447 TPEDPELIVRTQEGYVSKSVYDKLQYDEDQHQAKLALYSKEQDERYETKAQEYEE--KIQ 504
T D E+ + E +K K+++D +++ KL E+ E QE E ++
Sbjct: 840 TRTDDEIRAKDDELRATKERLLKMEHDFRENEKKLDQVIVERAVIQEQLQQESENSAELD 899
Query: 505 SIQAEIAELDAQMEQV------RLEHEEKLKLKQVEKSQALLETNVKHINAKGDLYKQTE 558
I+ + + ++E + RL EE+ K ++ + +ET + + +Q E
Sbjct: 900 DIRGRLQTRNQELEYIVNDMRDRLSEEEQQNEKNNDERRKQMET----VRDLEEQLEQEE 955
Query: 559 EIKNQTISDKEDKEVAHQTVQSEIDELLLLKDEVAKENQEHESKVEELTAELDNKTSALN 618
+ + + + DK + + + ++ + EL D++ KE + E KVE LT +L +
Sbjct: 956 QARQKLLLDKTNVDQRLRNLEERLVELQDAYDKLLKEKRLLEEKVEGLTTQLLDHEERAK 1015
Query: 619 ESLAKKDETNAEIQALEEEKARLEQEIKEAQELHQQNVSKIESIDNKEYLP----KVNEI 674
+ K ++ LE++ R Q E ++ ++ ++++E D+K++L KV E+
Sbjct: 1016 HGVKAKGRLENQLHELEQDLNRERQYKSELEQHKRKLLAELE--DSKDHLAEKMGKVEEL 1073
Query: 675 NTEISSLLASLGLIQQEIANQKVEFSSVT 703
N ++ L Q ++ E ++VT
Sbjct: 1074 NNQLMKRDEEL---QHQLTRYDEESANVT 1099
>Hs13259510 [DZ] KOG0971 Microtubule-associated protein dynactin DCTN1/Glued
Length = 1278
Score = 57.0 bits (136), Expect = 1e-07
Identities = 45/185 (24%), Positives = 95/185 (51%), Gaps = 17/185 (9%)
Query: 504 QSIQAEIAELDAQMEQVRLEH-EEKLKLKQVEKSQALLET----NVKHINAKGDLYKQTE 558
+ ++A++ +L+ ++E +RL+ E+K KLK++EK + LE K + DL ++ +
Sbjct: 218 EGLRAQVRDLEEKLETLRLKRAEDKAKLKELEKHKIQLEQVQEWKSKMQEQQADLQRRLK 277
Query: 559 EIKNQTISDKEDKEVAHQTVQSEID--ELLLLKDEVAKENQEH--------ESKVEELTA 608
E + + E KE + + D E+ L E+A+E E + +V+ELT
Sbjct: 278 EARKEAKEALEAKERYMEEMADTADAIEMATLDKEMAEERAESLQQEVEALKERVDELTT 337
Query: 609 ELDNKTSALNESLAKKDETNAEIQALEEEKARLEQEIKEAQELHQQNVSKIESIDNKEYL 668
+L+ + + E + ++ +++ LEE+ ARL+ + ++L + K E + ++ +
Sbjct: 338 DLEILKAEIEEKGSDGAASSYQLKQLEEQNARLKDALVRMRDL--SSSEKQEHVKLQKLM 395
Query: 669 PKVNE 673
K N+
Sbjct: 396 EKKNQ 400
>Hs13259508 [DZ] KOG0971 Microtubule-associated protein dynactin DCTN1/Glued
Length = 1144
Score = 57.0 bits (136), Expect = 1e-07
Identities = 45/185 (24%), Positives = 95/185 (51%), Gaps = 17/185 (9%)
Query: 504 QSIQAEIAELDAQMEQVRLEH-EEKLKLKQVEKSQALLET----NVKHINAKGDLYKQTE 558
+ ++A++ +L+ ++E +RL+ E+K KLK++EK + LE K + DL ++ +
Sbjct: 84 EGLRAQVRDLEEKLETLRLKRAEDKAKLKELEKHKIQLEQVQEWKSKMQEQQADLQRRLK 143
Query: 559 EIKNQTISDKEDKEVAHQTVQSEID--ELLLLKDEVAKENQEH--------ESKVEELTA 608
E + + E KE + + D E+ L E+A+E E + +V+ELT
Sbjct: 144 EARKEAKEALEAKERYMEEMADTADAIEMATLDKEMAEERAESLQQEVEALKERVDELTT 203
Query: 609 ELDNKTSALNESLAKKDETNAEIQALEEEKARLEQEIKEAQELHQQNVSKIESIDNKEYL 668
+L+ + + E + ++ +++ LEE+ ARL+ + ++L + K E + ++ +
Sbjct: 204 DLEILKAEIEEKGSDGAASSYQLKQLEEQNARLKDALVRMRDL--SSSEKQEHVKLQKLM 261
Query: 669 PKVNE 673
K N+
Sbjct: 262 EKKNQ 266
>Hs8923940 [Z] KOG0161 Myosin class II heavy chain
Length = 1941
Score = 56.6 bits (135), Expect = 2e-07
Identities = 45/181 (24%), Positives = 85/181 (46%), Gaps = 25/181 (13%)
Query: 486 KEQDERYETKAQEYEEKIQSIQAEIAELDAQME-QVRLEHEEKLKLKQVEKSQALLETNV 544
K++ + E K +E EEK+ ++ E +L Q++ + + + + Q+ K++ LE +
Sbjct: 866 KDELAKSEAKRKELEEKMVTLLKEKNDLQLQVQAEAEGLADAEERCDQLIKTKIQLEAKI 925
Query: 545 KHINAKGDLYKQTEEIKNQTISDKEDKEVAHQTVQSEIDELLLLKDEVAKENQEHESKVE 604
K + + + EEI + + K E ++ +ID+L L +V KE E+KV+
Sbjct: 926 KEVTERAE---DEEEINAELTAKKRKLEDECSELKKDIDDLELTLAKVEKEKHATENKVK 982
Query: 605 ELTAELDNKTSALNESLAKKDETNAEIQALEEEKARLEQEIKEAQELHQQNVSKIESIDN 664
LT E+ L+E A+L +E K QE HQQ + +++ ++
Sbjct: 983 NLTEEM---------------------AGLDETIAKLTKEKKALQEAHQQTLDDLQAEED 1021
Query: 665 K 665
K
Sbjct: 1022 K 1022
Score = 53.1 bits (126), Expect = 2e-06
Identities = 56/252 (22%), Positives = 126/252 (49%), Gaps = 53/252 (21%)
Query: 474 EDQHQAKLALYSKEQDERYETKA--QEYEEKIQS---IQAEIAELDAQMEQVRLEHE--- 525
E++ +AK AL Q R++ ++YEE+ +S +Q +++ + ++ Q R ++E
Sbjct: 1326 EEEIKAKNALAHALQSSRHDCDLLREQYEEEQESKAELQRALSKANTEVAQWRTKYETDA 1385
Query: 526 -------EKLKLKQVEKSQALLETNVKHINAKGDLYKQTEEIKNQTISDKEDKEVAHQTV 578
E+ K K ++ QA E +V+ +NAK ++T+ Q +
Sbjct: 1386 IQRTEELEEAKKKLAQRLQAA-EEHVEAVNAKCASLEKTK-----------------QRL 1427
Query: 579 QSEIDELLLLKDEVAKENQEHESKVEELTAELDNKTSALNESLA----KKDETNAEIQAL 634
Q+E+++L+L +V + N A LD K ++ LA K +ET+AE++A
Sbjct: 1428 QNEVEDLML---DVERTNAA--------CAALDKKQRNFDKILAEWKQKCEETHAELEAS 1476
Query: 635 EEEKARLEQEIKEAQELHQQNVSKIESI--DNKEYLPKVNEINTEIS---SLLASLGLIQ 689
++E L E+ + + +++++ ++E++ +NK +++++ +I+ + L I+
Sbjct: 1477 QKEARSLGTELFKIKNAYEESLDQLETLKRENKNLQQEISDLTEQIAEGGKRIHELEKIK 1536
Query: 690 QEIANQKVEFSS 701
+++ +K E +
Sbjct: 1537 KQVEQEKCELQA 1548
>Hs8923838 [S] KOG4643 Uncharacterized coiled-coil protein
Length = 742
Score = 56.6 bits (135), Expect = 2e-07
Identities = 60/249 (24%), Positives = 124/249 (49%), Gaps = 24/249 (9%)
Query: 473 DEDQHQAKLALYSKEQDERYETKAQEYEEKI----QSIQ-AEIAELDAQMEQVRLEHEEK 527
D + A L +++++R K + E +I QS+Q + D E+ +LE +
Sbjct: 409 DSVEGNASKILKMEKENQRLSKKVEILENEIVQEKQSLQNCQNLSKDLMKEKAQLEKTIE 468
Query: 528 LKLKQVEKSQALLETNVKHINAKGDLYKQTEEIKNQT-ISDKE-DKEVAHQTVQ---SEI 582
+ E+ +LE +H+N +Q +I + + D E + ++ H++++ S++
Sbjct: 469 TLRENSERQIKILEQENEHLNQTVSSLRQRSQISAEARVKDIEKENKILHESIKETSSKL 528
Query: 583 DELLLLKDEVAKENQEHESKVEELTAELDNKTSAL---NESLAKKDE----TNAEIQALE 635
++ K ++ KE + ++ K E EL+N+ L NE L KK T +I+ALE
Sbjct: 529 SKIEFEKRQIKKELEHYKEKGER-AEELENELHHLEKENELLQKKITNLKITCEKIEALE 587
Query: 636 EEKARLEQE---IKEAQELHQQNVSKIESI--DNKEYLPKVNEINTEISSL-LASLGLIQ 689
+E + LE+E +K+ + + ++ES+ +N + + E+ + SL AS+ + Q
Sbjct: 588 QENSELERENRKLKKTLDSFKNLTFQLESLEKENSQLDEENLELRRNVESLKCASMKMAQ 647
Query: 690 QEIANQKVE 698
++ N+++E
Sbjct: 648 LQLENKELE 656
>SPAC17C9.03 [J] KOG0401 Translation initiation factor 4F ribosome/mRNA-bridging
subunit (eIF-4G)
Length = 1403
Score = 56.2 bits (134), Expect = 2e-07
Identities = 65/272 (23%), Positives = 118/272 (42%), Gaps = 12/272 (4%)
Query: 413 FALFKRSKKPESSTKVAANAAAGTVVPGDDAPVATPEDPELIVRTQEGYVSKSVYDKLQY 472
FA + +K S+ K+ N T V ++P E R + + + +
Sbjct: 464 FAPIVKQQKKSSALKIV-NPVTHTEVVVPQKNASSPNPSETNSRAETPTAAPPQISEEEA 522
Query: 473 DEDQHQAKLALYSKEQDERYETKAQEYEEKIQSIQAEIAELDAQMEQVRLEHEEKLKLKQ 532
+ + KLA+ + Q++ ++ EEK + E A+ +A+ EQ + E EEK K +
Sbjct: 523 SQRKDAIKLAIQQRIQEKAEAEAKRKAEEKARLEAEENAKREAE-EQAKREAEEKAKREA 581
Query: 533 VEKSQALLETNVKHINAKGDLYKQTEEIKNQTISDKEDKEVAHQTVQSEIDELLLLKDEV 592
EK++ E K A+ + ++ EE + +K +E + + ++ +E
Sbjct: 582 EEKAKREAEEKAKR-EAEENAKREAEEKAKREAEEKAKREAEEKAKREAEEKAKREAEEK 640
Query: 593 AKENQEHESKVEELTAELDNKTSALNESLAKKDETNAEIQALEEEKARLEQEIKEAQELH 652
AK E ++K E AE K A E+ ++ E A+ +A E K E+++K E
Sbjct: 641 AKREAEEKAKRE---AEEKAKREA-EENAKREAEEKAKREAEENAKREAEEKVKRETE-- 694
Query: 653 QQNVSKIESIDNKEYLPKVNEINTEISSLLAS 684
+N + + K K EI + S+ LAS
Sbjct: 695 -ENAKRKAEEEGKREADKNPEIKS--SAPLAS 723
>Hs5453642 [D] KOG0018 Structural maintenance of chromosome protein 1 (sister
chromatid cohesion complex Cohesin subunit SMC1)
Length = 1233
Score = 56.2 bits (134), Expect = 2e-07
Identities = 56/243 (23%), Positives = 123/243 (50%), Gaps = 34/243 (13%)
Query: 486 KEQDERYETKAQ--EYEEKIQSIQAEIAELDAQMEQ-----VRLEHEEKLKLKQVEKSQA 538
K +DE E K + + + Q I+ EI E D+++ Q ++ + K+K++E ++
Sbjct: 258 KVEDELKEKKKELGKMMREQQQIEKEIKEKDSELNQKRPQYIKAKENTSHKIKKLEAAKK 317
Query: 539 LLETNVKHINA-KGDLYKQTEEIKNQTISDKEDKEVAHQTVQSEIDELLLLKDEVAKENQ 597
L+ KH KGD+ + +E+ + + +E +E + QS+ +L L +++V K ++
Sbjct: 318 SLQNAQKHYKKRKGDMDELEKEMLSVEKARQEFEERMEEESQSQGRDLTLEENQVKKYHR 377
Query: 598 EHESKVEELTAELDNKTSALN-ESLAKKDETNAEIQALEEEKARLEQEIKEAQELHQQNV 656
E + + A L + N + A +D + E + E +A+++Q+++E +E +Q+ +
Sbjct: 378 LKE-EASKRAATLAQELEKFNRDQKADQDRLDLEERKKVETEAKIKQKLREIEE-NQKRI 435
Query: 657 SKIE--------SIDNKEYLP------------KVNEINTEISSLLASLG---LIQQEIA 693
K+E S++ ++ L +++EIN E++ ++ LG + +QE +
Sbjct: 436 EKLEEYITTSKQSLEEQKKLEGELTEEVEMAKRRIDEINKELNQVMEQLGDARIDRQESS 495
Query: 694 NQK 696
Q+
Sbjct: 496 RQQ 498
Score = 53.9 bits (128), Expect = 1e-06
Identities = 48/251 (19%), Positives = 118/251 (46%), Gaps = 23/251 (9%)
Query: 468 DKLQYDEDQHQAKLALYSKEQDERYETKAQEYEEKIQSIQAEIAELDAQMEQVRLEHEEK 527
DKL+ E + + L + + +R E + ++ + + +Q + + +EQ + H
Sbjct: 672 DKLK--EKKERLTEELKEQMKAKRKEAELRQVQSQAHGLQMRLKYSQSDLEQTKTRH--- 726
Query: 528 LKLKQVEKSQALLETNVKHINAKGDLYKQTEEIKNQTISDKEDK--------------EV 573
L L EKS+ LE+ + + + + K+ + + + + D ++K E+
Sbjct: 727 LALNLQEKSK--LESELANFGPRINDIKRIIQSREREMKDLKEKMNQVEDEVFEEFCREI 784
Query: 574 AHQTVQSEIDELLLLKDEVAKENQEHESKVEELTAELDNKTSALNESLAKKDETNAEIQA 633
+ ++ +E + ++E+AK+ E E++ L +LD + + L E K ++
Sbjct: 785 GVRNIREFEEEKVKRQNEIAKKRLEFENQKTRLGIQLDFEKNQLKEDQDKVHMWEQTVKK 844
Query: 634 LEEEKARLEQEIKEAQELHQQNVSKIESIDNKEYLPK--VNEINTEISSLLASLGLIQQE 691
E E +L++E + ++ + +++++ + N+ K VN+ N E+ + LG +E
Sbjct: 845 DENEIEKLKKEEQRHMKIIDETMAQLQDLKNQHLAKKSEVNDKNHEMEEIRKKLGGANKE 904
Query: 692 IANQKVEFSSV 702
+ + + E +++
Sbjct: 905 MTHLQKEVTAI 915
>Hs14764231 [D] KOG0018 Structural maintenance of chromosome protein 1 (sister
chromatid cohesion complex Cohesin subunit SMC1)
Length = 1233
Score = 56.2 bits (134), Expect = 2e-07
Identities = 56/243 (23%), Positives = 123/243 (50%), Gaps = 34/243 (13%)
Query: 486 KEQDERYETKAQ--EYEEKIQSIQAEIAELDAQMEQ-----VRLEHEEKLKLKQVEKSQA 538
K +DE E K + + + Q I+ EI E D+++ Q ++ + K+K++E ++
Sbjct: 258 KVEDELKEKKKELGKMMREQQQIEKEIKEKDSELNQKRPQYIKAKENTSHKIKKLEAAKK 317
Query: 539 LLETNVKHINA-KGDLYKQTEEIKNQTISDKEDKEVAHQTVQSEIDELLLLKDEVAKENQ 597
L+ KH KGD+ + +E+ + + +E +E + QS+ +L L +++V K ++
Sbjct: 318 SLQNAQKHYKKRKGDMDELEKEMLSVEKARQEFEERMEEESQSQGRDLTLEENQVKKYHR 377
Query: 598 EHESKVEELTAELDNKTSALN-ESLAKKDETNAEIQALEEEKARLEQEIKEAQELHQQNV 656
E + + A L + N + A +D + E + E +A+++Q+++E +E +Q+ +
Sbjct: 378 LKE-EASKRAATLAQELEKFNRDQKADQDRLDLEERKKVETEAKIKQKLREIEE-NQKRI 435
Query: 657 SKIE--------SIDNKEYLP------------KVNEINTEISSLLASLG---LIQQEIA 693
K+E S++ ++ L +++EIN E++ ++ LG + +QE +
Sbjct: 436 EKLEEYITTSKQSLEEQKKLEGELTEEVEMAKRRIDEINKELNQVMEQLGDARIDRQESS 495
Query: 694 NQK 696
Q+
Sbjct: 496 RQQ 498
Score = 53.9 bits (128), Expect = 1e-06
Identities = 48/251 (19%), Positives = 118/251 (46%), Gaps = 23/251 (9%)
Query: 468 DKLQYDEDQHQAKLALYSKEQDERYETKAQEYEEKIQSIQAEIAELDAQMEQVRLEHEEK 527
DKL+ E + + L + + +R E + ++ + + +Q + + +EQ + H
Sbjct: 672 DKLK--EKKERLTEELKEQMKAKRKEAELRQVQSQAHGLQMRLKYSQSDLEQTKTRH--- 726
Query: 528 LKLKQVEKSQALLETNVKHINAKGDLYKQTEEIKNQTISDKEDK--------------EV 573
L L EKS+ LE+ + + + + K+ + + + + D ++K E+
Sbjct: 727 LALNLQEKSK--LESELANFGPRINDIKRIIQSREREMKDLKEKMNQVEDEVFEEFCREI 784
Query: 574 AHQTVQSEIDELLLLKDEVAKENQEHESKVEELTAELDNKTSALNESLAKKDETNAEIQA 633
+ ++ +E + ++E+AK+ E E++ L +LD + + L E K ++
Sbjct: 785 GVRNIREFEEEKVKRQNEIAKKRLEFENQKTRLGIQLDFEKNQLKEDQDKVHMWEQTVKK 844
Query: 634 LEEEKARLEQEIKEAQELHQQNVSKIESIDNKEYLPK--VNEINTEISSLLASLGLIQQE 691
E E +L++E + ++ + +++++ + N+ K VN+ N E+ + LG +E
Sbjct: 845 DENEIEKLKKEEQRHMKIIDETMAQLQDLKNQHLAKKSEVNDKNHEMEEIRKKLGGANKE 904
Query: 692 IANQKVEFSSV 702
+ + + E +++
Sbjct: 905 MTHLQKEVTAI 915
>CE07306 [Z] KOG0161 Myosin class II heavy chain
Length = 1974
Score = 56.2 bits (134), Expect = 2e-07
Identities = 91/431 (21%), Positives = 169/431 (39%), Gaps = 58/431 (13%)
Query: 456 RTQEGYVSKSVYDKLQYDEDQHQAKLALYSKEQDERYETKAQEYEEKIQSIQAEIAELDA 515
+TQE K + + E + QA L +E+D + E EE+ + A+ A+L+
Sbjct: 873 KTQEERKRKDMEAENARLEAEKQALLIQLEQERDS-----SAEGEERSAKLLAQKADLEK 927
Query: 516 QMEQVRLEHEEKLKLKQVEKSQALLETNVKHINAKGDLYKQTEEIKNQTISDKE-DKEVA 574
QM + + L E+ A L K I + K+T TI +E +K+
Sbjct: 928 QMANMNDQ------LCDEEEKNAALTKQKKKIEQDNEGLKKTVSDLETTIKKQESEKQAK 981
Query: 575 HQTVQSEIDELLLLKDEVAKENQE--HESKV-----EELTAELDNKTSALNESLAKKDET 627
++S DE+ + ++K N+E H+ +V E++ AE ++K + LN++ AK + T
Sbjct: 982 DHQIRSLQDEIQSQDEVISKLNKEKKHQEEVNRKLLEDIQAE-EDKVNHLNKTKAKLEST 1040
Query: 628 NAEI-----------QALEEEKARLEQEIKEAQEL--------HQQ---------NVSKI 659
E+ Q E+++ ++E E+K AQEL H+Q +S I
Sbjct: 1041 LDELEDTLEREKRGRQDCEKQRRKVEGELKIAQELIEELNRHKHEQEQVIKKKDIELSSI 1100
Query: 660 ES-IDNKEYLPKVNEINTEISSLLASLGLIQQEI-----ANQKVEFSSVTXXXXXXXXXX 713
+S +++++ L V ++ +I LLA + +++E+ + K E +
Sbjct: 1101 QSRLEDEQSL--VAKLQRQIKELLARIQELEEELDAERNSRSKAEKARNEMQMELEELGD 1158
Query: 714 XXXXXXXXXXXXXXXXXXXXXXXTEYEKQAEEARLKHEEELANLKQTHDXXXXXXXXXXX 773
+ + E+A + E +A L++ H+
Sbjct: 1159 RLDEAGGATQAQIELNKKREAELAKLRQDLEDAAINSETSMAALRKKHNDAVAELSDQLD 1218
Query: 774 XXXXXXXXXXXXXXXXXXXXXXXXGEKAIEAQQRGNPE--DKRLEAEHEEKLRRQAEAAS 831
+EA+QR N E K+LEA+ + + E A
Sbjct: 1219 TIQKMRGKLEREKNDKQREVDELQQSADVEAKQRQNCERMAKQLEAQLTDMTLKSDEQAR 1278
Query: 832 AVENALKSSNK 842
++ NK
Sbjct: 1279 LIQELTMGKNK 1289
Score = 53.9 bits (128), Expect = 1e-06
Identities = 55/217 (25%), Positives = 104/217 (47%), Gaps = 28/217 (12%)
Query: 487 EQDERYETKAQEYEEKIQSIQAEIAELDAQMEQVRLEHEEKLKLKQVEK----SQALLET 542
E+ E E K + EE + Q E D + E RLE E++ L Q+E+ S E
Sbjct: 857 EEFEALEKKFKVLEE--EKTQEERKRKDMEAENARLEAEKQALLIQLEQERDSSAEGEER 914
Query: 543 NVKHINAKGDLYKQTEEIKNQTISDKEDKEVAHQTVQSEIDELLLLKDEVAKENQEHESK 602
+ K + K DL KQ + +Q + D+E+K A L K ++ ++N+ +
Sbjct: 915 SAKLLAQKADLEKQMANMNDQ-LCDEEEKNAA----------LTKQKKKIEQDNEGLKKT 963
Query: 603 VEELTAELDNKTSALNESLAKKDETNA---EIQALEEEKARLEQEIKEAQELHQQNVSKI 659
V +L + + S E AK + + EIQ+ +E ++L +E K +E++++ + I
Sbjct: 964 VSDLETTIKKQES---EKQAKDHQIRSLQDEIQSQDEVISKLNKEKKHQEEVNRKLLEDI 1020
Query: 660 ESIDNKEYLPKVNEINTEISSLLASLGLIQQEIANQK 696
++ ++ KVN +N + L ++L ++ + +K
Sbjct: 1021 QAEED-----KVNHLNKTKAKLESTLDELEDTLEREK 1052
>7303885 [U] KOG4809 Rab6 GTPase-interacting protein involved in
endosome-to-TGN transport
Length = 1456
Score = 56.2 bits (134), Expect = 2e-07
Identities = 49/193 (25%), Positives = 99/193 (50%), Gaps = 18/193 (9%)
Query: 468 DKLQYDEDQHQAKLALYSKEQDERYETKAQEYEEKIQSIQAEIAELDAQMEQVRLEHEEK 527
DK + + QA+L + ++ ER +A +EK++ Q E+ L A++E + E +E
Sbjct: 321 DKASAELRRTQAELRV-TQSDAERAREEAAALQEKLEKSQGEVYRLKAKLENAQGE-QES 378
Query: 528 LKLKQVEKSQALLETNVKHINAKGD-LYKQTEEIKNQ---TISDKEDKEVAHQTVQS--- 580
L+ +++EK+Q+ V I+A D + + E+IK + T + ++ H+ +Q+
Sbjct: 379 LR-QELEKAQS----GVSRIHADRDRAFSEVEKIKEEMERTQATLGKSQLQHEKLQNSLD 433
Query: 581 ----EIDELLLLKDEVAKENQEHESKVEELTAELDNKTSALNESLAKKDETNAEIQALEE 636
E+D L D+ EN+ + E+LT + DN S L+++L + E + L
Sbjct: 434 KAQNEVDHLQDKLDKACTENRRLVLEKEKLTYDYDNLQSQLDKALGQAARMQKERETLSL 493
Query: 637 EKARLEQEIKEAQ 649
+ R+ +++++ Q
Sbjct: 494 DTDRIREKLEKTQ 506
>Hs4503509 [J] KOG2072 Translation initiation factor 3 subunit a (eIF-3a)
Length = 1382
Score = 55.8 bits (133), Expect = 3e-07
Identities = 52/241 (21%), Positives = 118/241 (48%), Gaps = 18/241 (7%)
Query: 470 LQYDEDQHQAKLALY---SKEQDERYETKAQEYEEK--------IQSIQAEIAELDAQME 518
LQ E+QHQ + Y S+++ +R + Q EE+ IQ + E+ + +A+++
Sbjct: 543 LQEKEEQHQLAVTAYLKNSRKEHQRILARRQTIEERKERLESLNIQREKEELEQREAELQ 602
Query: 519 QVRLEHEEKLKLKQVEKSQALLETNVKHINAKGDLYKQTEEIKNQTISDKEDKEVAHQTV 578
+VR EE+L+ + E+ + + + I K + ++ E+IK + K K++ + +
Sbjct: 603 KVRKAEEERLRQEAKEREKERILQEHEQIKKK-TVRERLEQIKKTELGAKAFKDIDIEDL 661
Query: 579 QSEIDELLLLKDEVAKENQEHESKVEELTAELDNKTSALNE-SLAKKDETNAEIQALEEE 637
+ E+D ++ AK+ ++ E + +EL L N+ ++ AK+ E I++ EE
Sbjct: 662 E-ELDPDFIM----AKQVEQLEKEKKELQERLKNQEKKIDYFERAKRLEEIPLIKSAYEE 716
Query: 638 KARLEQEIKEAQELHQQNVSKIESIDNKEYLPKVNEINTEISSLLASLGLIQQEIANQKV 697
+ + ++ E QE + ++E E+ +++ + + + L +Q + +K+
Sbjct: 717 QRIKDMDLWEQQEEERITTMQLEREKALEHKNRMSRMLEDRDLFVMRLKAARQSVYEEKL 776
Query: 698 E 698
+
Sbjct: 777 K 777
>Hs20539050 [Z] KOG1003 Actin filament-coating protein tropomyosin
Length = 285
Score = 55.8 bits (133), Expect = 3e-07
Identities = 62/216 (28%), Positives = 109/216 (49%), Gaps = 25/216 (11%)
Query: 469 KLQYDEDQHQAKLALYSKEQDERYETKAQEYEEKIQSIQAEIAELDAQMEQVRLE---HE 525
KL+ ED+ L YS+ + E K + E+K +AE+A L+ +++ V E +
Sbjct: 50 KLKGTEDE----LDKYSEALKDAQE-KLELAEKKAADAEAEVASLNRRIQLVEEELDRAQ 104
Query: 526 EKL-----KLKQVEKSQALLETNVKHINAKGDLYKQTEEIKNQTISDKEDKEVAHQTVQS 580
E+L KL++ EK+ E +K I + K E+++ Q I KE K +A + +
Sbjct: 105 ERLATALQKLEEAEKAADESERGMKVIENRA--LKDEEKMELQEIQLKEAKHIAEEADRK 162
Query: 581 --EIDELLLLKDEVAKENQEH----ESKVEELTAELDNKTSALNESLAKKDETNAEIQAL 634
E+ L++ + + +E ESK EL EL N T+ L A+ ++ + +
Sbjct: 163 YEEVARKLVIIEGDLERTEERAELAESKCSELEEELKNVTNNLKSLEAQAEKYSQKEDKY 222
Query: 635 EEEKARLEQEIKEAQ---ELHQQNVSKIE-SIDNKE 666
EEE L ++KEA+ E +++V+K+E +ID+ E
Sbjct: 223 EEEIKILTDKLKEAETRAEFAERSVAKLEKTIDDLE 258
>Hs13124879 [Z] KOG0161 Myosin class II heavy chain
Length = 1972
Score = 55.8 bits (133), Expect = 3e-07
Identities = 61/255 (23%), Positives = 119/255 (45%), Gaps = 25/255 (9%)
Query: 454 IVRTQEGYVSKSVYDKLQYDEDQHQAKLALYSKEQDERYETKAQEYEEKIQSIQAEIAEL 513
+ R +E +K D+LQ +++ Q K KE ++++ +E + +QAE EL
Sbjct: 847 VTRQEEEMQAKE--DELQKTKERQQ-KAENELKELEQKHSQLTEEKNLLQEQLQAE-TEL 902
Query: 514 DAQMEQVRLE------------HEEKLKLKQVE-KSQALLETNVKHINAKGDLYKQTEEI 560
A+ E++R+ HE + +L++ E + Q L K DL +Q EE
Sbjct: 903 YAEAEEMRVRLAAKKQELEEILHEMEARLEEEEDRGQQLQAERKKMAQQMLDLEEQLEEE 962
Query: 561 KNQTISDKEDKEVAHQTVQSEIDELLLLKDE---VAKENQEHESKVEELTAELDNKTSAL 617
+ + +K A ++ DE+L++ D+ ++KE + E ++ +LT L +
Sbjct: 963 EAARQKLQLEKVTAEAKIKKLEDEILVMDDQNNKLSKERKLLEERISDLTTNLAEEEEKA 1022
Query: 618 NESLAKKDETNAEIQALEEEKARLEQEIKEAQELHQQNVSKIESIDNKEYLPKVNEINTE 677
K++ + I LE RL++E K QEL + K+E D ++ ++ ++ +
Sbjct: 1023 KNLTKLKNKHESMISELE---VRLKKEEKSRQELEKLK-RKLEG-DASDFHEQIADLQAQ 1077
Query: 678 ISSLLASLGLIQQEI 692
I+ L L ++E+
Sbjct: 1078 IAELKMQLAKKEEEL 1092
Score = 51.6 bits (122), Expect = 5e-06
Identities = 54/241 (22%), Positives = 108/241 (44%), Gaps = 34/241 (14%)
Query: 491 RYETKAQEYEEKIQSIQAEIAELDAQMEQVRLEHEEKL---------------KLKQVEK 535
+ E A ++ E+I +QA+IAEL Q+ + E + L K++++E
Sbjct: 1059 KLEGDASDFHEQIADLQAQIAELKMQLAKKEEELQAALARLDDEIAQKNNALKKIRELEG 1118
Query: 536 SQALLETNVKHINA--------KGDLYKQTEEIKNQTISDKEDKEVAHQTVQSEID-ELL 586
+ L+ ++ A K DL ++ E +K + + D D Q ++++ + E+
Sbjct: 1119 HISDLQEDLDSERAARNKAEKQKRDLGEELEALKTE-LEDTLDSTATQQELRAKREQEVT 1177
Query: 587 LLKDEVAKENQEHESKVEELTAELDNKTSALNESLAKKDETNAEI----QALEEEKARLE 642
+LK + +E + HE++V+E+ + L E L + A + Q LE+E A L
Sbjct: 1178 VLKKALDEETRSHEAQVQEMRQKHAQAVEELTEQLEQFKRAKANLDKNKQTLEKENADLA 1237
Query: 643 QEIKEAQELHQQNVSKIESIDNKEYLPKVNEINTEISSLLASLGLIQQEIANQKVEFSSV 702
E++ + Q+ K K+ +V E+ ++ S + + ++ + E SV
Sbjct: 1238 GELRVLGQAKQEVEHK-----KKKLEAQVQELQSKCSDGERARAELNDKVHKLQNEVESV 1292
Query: 703 T 703
T
Sbjct: 1293 T 1293
>Hs13124877 [Z] KOG0161 Myosin class II heavy chain
Length = 1266
Score = 55.8 bits (133), Expect = 3e-07
Identities = 61/255 (23%), Positives = 119/255 (45%), Gaps = 25/255 (9%)
Query: 454 IVRTQEGYVSKSVYDKLQYDEDQHQAKLALYSKEQDERYETKAQEYEEKIQSIQAEIAEL 513
+ R +E +K D+LQ +++ Q K KE ++++ +E + +QAE EL
Sbjct: 847 VTRQEEEMQAKE--DELQKTKERQQ-KAENELKELEQKHSQLTEEKNLLQEQLQAE-TEL 902
Query: 514 DAQMEQVRLE------------HEEKLKLKQVE-KSQALLETNVKHINAKGDLYKQTEEI 560
A+ E++R+ HE + +L++ E + Q L K DL +Q EE
Sbjct: 903 YAEAEEMRVRLAAKKQELEEILHEMEARLEEEEDRGQQLQAERKKMAQQMLDLEEQLEEE 962
Query: 561 KNQTISDKEDKEVAHQTVQSEIDELLLLKDE---VAKENQEHESKVEELTAELDNKTSAL 617
+ + +K A ++ DE+L++ D+ ++KE + E ++ +LT L +
Sbjct: 963 EAARQKLQLEKVTAEAKIKKLEDEILVMDDQNNKLSKERKLLEERISDLTTNLAEEEEKA 1022
Query: 618 NESLAKKDETNAEIQALEEEKARLEQEIKEAQELHQQNVSKIESIDNKEYLPKVNEINTE 677
K++ + I LE RL++E K QEL + K+E D ++ ++ ++ +
Sbjct: 1023 KNLTKLKNKHESMISELE---VRLKKEEKSRQELEKLK-RKLEG-DASDFHEQIADLQAQ 1077
Query: 678 ISSLLASLGLIQQEI 692
I+ L L ++E+
Sbjct: 1078 IAELKMQLAKKEEEL 1092
>Hs13124875 [Z] KOG0161 Myosin class II heavy chain
Length = 1938
Score = 55.8 bits (133), Expect = 3e-07
Identities = 61/255 (23%), Positives = 119/255 (45%), Gaps = 25/255 (9%)
Query: 454 IVRTQEGYVSKSVYDKLQYDEDQHQAKLALYSKEQDERYETKAQEYEEKIQSIQAEIAEL 513
+ R +E +K D+LQ +++ Q K KE ++++ +E + +QAE EL
Sbjct: 847 VTRQEEEMQAKE--DELQKTKERQQ-KAENELKELEQKHSQLTEEKNLLQEQLQAE-TEL 902
Query: 514 DAQMEQVRLE------------HEEKLKLKQVE-KSQALLETNVKHINAKGDLYKQTEEI 560
A+ E++R+ HE + +L++ E + Q L K DL +Q EE
Sbjct: 903 YAEAEEMRVRLAAKKQELEEILHEMEARLEEEEDRGQQLQAERKKMAQQMLDLEEQLEEE 962
Query: 561 KNQTISDKEDKEVAHQTVQSEIDELLLLKDE---VAKENQEHESKVEELTAELDNKTSAL 617
+ + +K A ++ DE+L++ D+ ++KE + E ++ +LT L +
Sbjct: 963 EAARQKLQLEKVTAEAKIKKLEDEILVMDDQNNKLSKERKLLEERISDLTTNLAEEEEKA 1022
Query: 618 NESLAKKDETNAEIQALEEEKARLEQEIKEAQELHQQNVSKIESIDNKEYLPKVNEINTE 677
K++ + I LE RL++E K QEL + K+E D ++ ++ ++ +
Sbjct: 1023 KNLTKLKNKHESMISELE---VRLKKEEKSRQELEKLK-RKLEG-DASDFHEQIADLQAQ 1077
Query: 678 ISSLLASLGLIQQEI 692
I+ L L ++E+
Sbjct: 1078 IAELKMQLAKKEEEL 1092
Score = 51.6 bits (122), Expect = 5e-06
Identities = 54/241 (22%), Positives = 108/241 (44%), Gaps = 34/241 (14%)
Query: 491 RYETKAQEYEEKIQSIQAEIAELDAQMEQVRLEHEEKL---------------KLKQVEK 535
+ E A ++ E+I +QA+IAEL Q+ + E + L K++++E
Sbjct: 1059 KLEGDASDFHEQIADLQAQIAELKMQLAKKEEELQAALARLDDEIAQKNNALKKIRELEG 1118
Query: 536 SQALLETNVKHINA--------KGDLYKQTEEIKNQTISDKEDKEVAHQTVQSEID-ELL 586
+ L+ ++ A K DL ++ E +K + + D D Q ++++ + E+
Sbjct: 1119 HISDLQEDLDSERAARNKAEKQKRDLGEELEALKTE-LEDTLDSTATQQELRAKREQEVT 1177
Query: 587 LLKDEVAKENQEHESKVEELTAELDNKTSALNESLAKKDETNAEI----QALEEEKARLE 642
+LK + +E + HE++V+E+ + L E L + A + Q LE+E A L
Sbjct: 1178 VLKKALDEETRSHEAQVQEMRQKHAQAVEELTEQLEQFKRAKANLDKNKQTLEKENADLA 1237
Query: 643 QEIKEAQELHQQNVSKIESIDNKEYLPKVNEINTEISSLLASLGLIQQEIANQKVEFSSV 702
E++ + Q+ K K+ +V E+ ++ S + + ++ + E SV
Sbjct: 1238 GELRVLGQAKQEVEHK-----KKKLEAQVQELQSKCSDGERARAELNDKVHKLQNEVESV 1292
Query: 703 T 703
T
Sbjct: 1293 T 1293
>CE27096 [BDL] KOG0979 Structural maintenance of chromosome protein
SMC5/Spr18 SMC superfamily
Length = 1076
Score = 55.5 bits (132), Expect = 4e-07
Identities = 44/196 (22%), Positives = 98/196 (49%), Gaps = 12/196 (6%)
Query: 475 DQHQAKLALYSKEQDERYETKAQEYEEKIQSIQAEIAELDAQMEQVRLEHEEKLKLKQVE 534
+ ++ KLAL SK + + K E+E+ + +AE+ +D M + R E + + + E
Sbjct: 219 ENYRKKLALQSKLRLLEKKMKIMEFEKFDREYKAELQNMDGAMIEYR---EVEKSIAECE 275
Query: 535 KSQALLETNVKHINAK-GDLYKQTEEIKNQTISDKEDKEVAHQTVQSEIDELLLLKDEVA 593
K + LE +K ++ + + EI + + +K DK++ +Q +L +
Sbjct: 276 KHRKNLEDRIKKDRSQISQMQRSCNEILAK-VQEKGDKKLMEDMMQRAKAKL----ESAK 330
Query: 594 KENQEHESKVEELTAELDNKTSALNES---LAKKDETNAEIQALEEEKARLEQEIKEAQE 650
K +HE VE+ +D + L E+ L +E +E+++LE++ + E++ ++ ++
Sbjct: 331 KAADQHEKDVEKARKMIDQARARLQEAVDTLNGYEEFQSEMKSLEQKYSTAERDSRQEED 390
Query: 651 LHQQNVSKIESIDNKE 666
Q+ ++ ++NK+
Sbjct: 391 AIQKKSYEMRQLENKK 406
>Hs4759044 [T] KOG0612 Rho-associated coiled-coil containing protein kinase
Length = 1388
Score = 55.1 bits (131), Expect = 5e-07
Identities = 56/237 (23%), Positives = 108/237 (44%), Gaps = 16/237 (6%)
Query: 470 LQYDEDQHQAKLALYSKEQD---ERYETKAQEYEEKIQSIQAEIAELDAQMEQVRLEHEE 526
L D Q Q K+ K++D E + E++ Q +L Q +QV
Sbjct: 764 LDCDLKQSQQKINELLKQKDVLNEDVRNLTLKIEQETQKRCLTQNDLKMQTQQVNTLKMS 823
Query: 527 KLKLKQVEKSQALLETNVKHINAKGDLYKQTEEIKNQTISDKEDKEVAHQTV-QSEIDEL 585
+ +LKQ ++ N++ NA+ +Q + + + + D+ + E T+ ++++ EL
Sbjct: 824 EKQLKQENNHLMEMKMNLEKQNAELRKERQDADGQMKELQDQLEAEQYFSTLYKTQVREL 883
Query: 586 LLLKDEVAKENQEHESKVEELTAELDNKTSALNESLAKKDE-------TNAEIQALEEEK 638
+E K +E + K +EL E D+ + L +L K D + LE+EK
Sbjct: 884 KEECEEKTKLGKELQQKKQELQDERDSLAAQLEITLTKADSEQLARSIAEEQYSDLEKEK 943
Query: 639 ARLEQEIKEAQELHQQNVSKIESIDNKEYLPKVNEINTEISSLLASLGLIQQEIANQ 695
E EIKE H+Q +++ ++ + + E N ++S +A+L ++E+ N+
Sbjct: 944 IMKELEIKEMMARHKQELTEKDAT-----IASLEETNRTLTSDVANLANEKEELNNK 995
>Hs20536595 [T] KOG0612 Rho-associated coiled-coil containing protein kinase
Length = 1388
Score = 55.1 bits (131), Expect = 5e-07
Identities = 56/237 (23%), Positives = 108/237 (44%), Gaps = 16/237 (6%)
Query: 470 LQYDEDQHQAKLALYSKEQD---ERYETKAQEYEEKIQSIQAEIAELDAQMEQVRLEHEE 526
L D Q Q K+ K++D E + E++ Q +L Q +QV
Sbjct: 764 LDCDLKQSQQKINELLKQKDVLNEDVRNLTLKIEQETQKRCLTQNDLKMQTQQVNTLKMS 823
Query: 527 KLKLKQVEKSQALLETNVKHINAKGDLYKQTEEIKNQTISDKEDKEVAHQTV-QSEIDEL 585
+ +LKQ ++ N++ NA+ +Q + + + + D+ + E T+ ++++ EL
Sbjct: 824 EKQLKQENNHLMEMKMNLEKQNAELRKERQDADGQMKELQDQLEAEQYFSTLYKTQVREL 883
Query: 586 LLLKDEVAKENQEHESKVEELTAELDNKTSALNESLAKKDE-------TNAEIQALEEEK 638
+E K +E + K +EL E D+ + L +L K D + LE+EK
Sbjct: 884 KEECEEKTKLGKELQQKKQELQDERDSLAAQLEITLTKADSEQLARSIAEEQYSDLEKEK 943
Query: 639 ARLEQEIKEAQELHQQNVSKIESIDNKEYLPKVNEINTEISSLLASLGLIQQEIANQ 695
E EIKE H+Q +++ ++ + + E N ++S +A+L ++E+ N+
Sbjct: 944 IMKELEIKEMMARHKQELTEKDAT-----IASLEETNRTLTSDVANLANEKEELNNK 995
>At1g79830 [K] KOG4673 Transcription factor TMF TATA element modulatory factor
Length = 918
Score = 55.1 bits (131), Expect = 5e-07
Identities = 58/269 (21%), Positives = 126/269 (46%), Gaps = 18/269 (6%)
Query: 442 DAPVATPEDPELIVRTQEGYVSKSVYDKLQYDEDQHQAKLALYSKEQDERYETKAQEYEE 501
++PVA P ++ +G +S K ++ + + S+E D R +T +
Sbjct: 269 ESPVAHPS----LIFESDGSPYESSIPKRSSSDEISERIVDFVSREIDSRLDTSELNESQ 324
Query: 502 KIQSIQAEIAELDAQMEQVRLEHEEKLKLKQVE----KSQALLETNVKHINAKGDLYKQT 557
+ S D +E + + E K+ ++ ++QA + K ++ L T
Sbjct: 325 RSSSATNVSDSADVILELEKTKKEIKMLENALQGAARQAQAKADEIAKLMHENEQLKSVT 384
Query: 558 EEIKNQTISDKED--KEVAHQ---TVQSEIDELLLLKDEVAKENQEHESKVEELTAELDN 612
E++K ++ + + +E HQ T++ ++ L +D + +E ++K + A L
Sbjct: 385 EDLKRKSNEAEVESLREEYHQRVATLERKVYALTKERDTLRRE----QNKKSDAAALLKE 440
Query: 613 KTSALNESLAKKDETNAEIQALEEEKARLEQEIKEAQELHQQNVSKIESIDNKEYLPKVN 672
K +N+ +A+ +E + + A E + +L +I+EA+E + ++K++S +NK K +
Sbjct: 441 KDEIINQVMAEGEELSKKQAAQEAQIRKLRAQIREAEEEKKGLITKLQSEENKVESIKRD 500
Query: 673 EINTEISSLLASLGLIQQEIANQKVEFSS 701
+ TE L ++ Q E+ +QK +S+
Sbjct: 501 KTATE-KLLQETIEKHQAELTSQKDYYSN 528
>At1g04600 [Z] KOG0160 Myosin class V heavy chain
Length = 1730
Score = 55.1 bits (131), Expect = 5e-07
Identities = 64/253 (25%), Positives = 117/253 (45%), Gaps = 26/253 (10%)
Query: 428 VAANAAAGTVVPGDDAPVATPEDPELIVRTQEGYVSKSVYDKLQYDEDQHQAKLALYSKE 487
V AA T G VA E L + +E + KL+ ++ + L L +
Sbjct: 851 VRTKKAAITTQCGWRVKVARRELRNLKMAAKETGALQDAKTKLENQVEELTSNLELEKQM 910
Query: 488 QDERYETKAQEYEEKIQSIQAEIAELDAQMEQVRLEHEEKLKLKQVEKSQALLETNVKHI 547
+ E E K+QE E +QS+ +I +++L ++ K K++ Q++L T++K
Sbjct: 911 RMEIEEAKSQEIEA-LQSVLTDI--------KLQLRDTQETKSKEISDLQSVL-TDIKL- 959
Query: 548 NAKGDLYKQTEEIKNQTISDKEDKEVAHQTVQSEIDEL---LLLKDEVAKENQEHESKVE 604
+ T+E K++ ISD + A Q +Q EI+EL L + +++A EN++ + V
Sbjct: 960 -----QLRDTQETKSKEISDLQS---ALQDMQLEIEELSKGLEMTNDLAAENEQLKESVS 1011
Query: 605 ELTAELDNKTSALNE-SLAKKDETNAEIQALEEEK-ARLEQEIKEAQELHQQNVSKIESI 662
L ++D E S ++ E+ +++ +LE E ++ + L KI+ +
Sbjct: 1012 SLQNKIDESERKYEEISKISEERIKDEVPVIDQSAIIKLETENQKLKALVSSMEEKIDEL 1071
Query: 663 DNK--EYLPKVNE 673
D K E P + E
Sbjct: 1072 DRKHDETSPNITE 1084
>CE09197 [Z] KOG0161 Myosin class II heavy chain
Length = 872
Score = 54.7 bits (130), Expect = 6e-07
Identities = 56/227 (24%), Positives = 110/227 (47%), Gaps = 18/227 (7%)
Query: 445 VATPEDPELIVRTQEGYVSKSVYDKLQYDEDQHQAKLALYSKEQDE---RYETKAQEYEE 501
V T D E I R+ + ++ + + A++AL+ +E ++ + K EYEE
Sbjct: 270 VRTALDEESIARSDAEHKLNLANTEITQWKSKFDAEVALHHEEVEDLRKKMLQKQAEYEE 329
Query: 502 KIQSIQAEIAELDAQMEQVRLEHEEKLKLKQVEKSQ---ALLETNVKHINAKGDLYKQTE 558
+I+ + +I++L+ RL+ E ++ + +EK+Q ALLE A+ L +Q
Sbjct: 330 QIEIMLQKISQLEKAKS--RLQSEVEVLIVDLEKAQNTIALLE------RAREQLERQVG 381
Query: 559 EIKNQTISDKEDKEVAHQTVQSEIDELLLLKDEVAKENQEHESKVEELTAELDNKTSALN 618
E+K + + E A + +++ EL +K K ++ E+ E +L ++
Sbjct: 382 ELKVRIDEITVELEAAQRELRAVNAELQKMKHLYEKAVEQKEALARE-NKKLHDELHEAK 440
Query: 619 ESLAKKDETNAEIQALEEEKARLEQEIKEAQELHQQNVSKIESIDNK 665
E+LA + N ++ L+ E ARL EI+E Q ++ ++ +N+
Sbjct: 441 EALA---DANRKLHELDLENARLAGEIRELQTALKEADAQRRDAENR 484
>YKR095w [S] KOG4674 Uncharacterized conserved coiled-coil protein
Length = 1875
Score = 54.3 bits (129), Expect = 8e-07
Identities = 39/195 (20%), Positives = 95/195 (48%), Gaps = 5/195 (2%)
Query: 485 SKEQDERYETKAQEYEEKIQSIQAEIAELDAQMEQVRLEHEEKLKLKQVEKSQALLETNV 544
S E+ E++ + +E++++ + + AE + + ++R + +E+LK ++ SQ L V
Sbjct: 1297 SSSDYEKLESEIENLKEELENKERQGAEAEEKFNRLRRQAQERLKTSKL--SQDSLTEQV 1354
Query: 545 KHINAKGDLYKQTEEIKNQTISDKEDKEVAHQTVQSEIDELLLLKDEVAKENQEHESKVE 604
+ ++ + + N I + ++ +VA ++++ + L+++ K ++E ++K+E
Sbjct: 1355 NSLRDAKNVLENSLSEANARIEELQNAKVAQGN--NQLEAIRKLQEDAEKASRELQAKLE 1412
Query: 605 ELTAELDNKTSALNESLAK-KDETNAEIQALEEEKARLEQEIKEAQELHQQNVSKIESID 663
E T ++ + LNE + K+E + Q ++ +A E + + + E
Sbjct: 1413 ESTTSYESTINGLNEEITTLKEEIEKQRQIQQQLQATSANEQNDLSNIVESMKKSFEEDK 1472
Query: 664 NKEYLPKVNEINTEI 678
K K E+N +I
Sbjct: 1473 IKFIKEKTQEVNEKI 1487
>Hs14772793 [Z] KOG0161 Myosin class II heavy chain
Length = 1220
Score = 54.3 bits (129), Expect = 8e-07
Identities = 50/175 (28%), Positives = 80/175 (45%), Gaps = 27/175 (15%)
Query: 493 ETKAQEYEEKIQSIQAEIAELDAQM--EQVRLEHEEKLKLKQVEKSQALLETNVKHINAK 550
E K QE EE SI E +L Q+ EQ L E+ + + KS+ LE VK ++ +
Sbjct: 572 EAKRQELEETHVSITQEKNDLALQLQAEQDNLADAEE-RCHLLIKSKVQLEGKVKELSER 630
Query: 551 GDLYKQTEEIKNQTISDKEDKEVAHQTVQSEIDELLLLKDEVAKENQEHESKVEELTAEL 610
+ EE+ + + E ++ +ID+L L + KE Q E+KV+ LT E+
Sbjct: 631 ---LEDEEEVNADLAARRRKLEDECTELKKDIDDLKLTLAKAEKEKQATENKVKNLTEEM 687
Query: 611 DNKTSALNESLAKKDETNAEIQALEEEKARLEQEIKEAQELHQQNVSKIESIDNK 665
AL+E ARL +E K QE HQQ + +++ +++
Sbjct: 688 ---------------------AALDESVARLTKEKKALQEAHQQALGDLQAEEDR 721
>Hs4506751 [ZR] KOG4568 Cytoskeleton-associated protein and related proteins
Length = 1427
Score = 53.9 bits (128), Expect = 1e-06
Identities = 58/243 (23%), Positives = 115/243 (46%), Gaps = 16/243 (6%)
Query: 463 SKSVYDKLQYDEDQHQAKLALYSKEQDERYETKAQEYEEKIQSIQ-------AEIAELDA 515
++S+ KL++ ++ +AL+ + + + Q EE S AE AEL
Sbjct: 591 NESLKSKLEHANKENSDVIALWKSKLETAIASHQQAMEELKVSFSKGLGTETAEFAELKT 650
Query: 516 QMEQVRLEHEEKLK--LKQVEKSQALLETNVKHINAKGDLYKQTEEIKN--QTISDKEDK 571
Q+E++RL+++ +++ Q + +A ++ + AK L K +E +N + I K DK
Sbjct: 651 QIEKMRLDYQHEIENLQNQQDSERAAHAKEMEALRAK--LMKVIKEKENSLEAIRSKLDK 708
Query: 572 EVAHQTVQSEIDELLLLKDEV-AKENQEHESKVEELTAELDNKTSALNESLAKKDETNAE 630
V+ E L + E+ KE + ++K E T +DN TS L + K + +A
Sbjct: 709 AEDQHLVEMEDTLNKLQEAEIKVKELEVLQAKCNEQTKVIDNFTSQLKATEEKLLDLDAL 768
Query: 631 IQALEEEKARLEQEIKEAQELHQQNVSKIESIDNKEYLPKVNEINTEISSLLASLGLIQQ 690
+A E K+ + +++++ E ++ + +E N E K + I E+ L +Q+
Sbjct: 769 RKASSEGKSEM-KKLRQQLEAAEKQIKHLEIEKNAE-SSKASSITRELQGRELKLTNLQE 826
Query: 691 EIA 693
++
Sbjct: 827 NLS 829
>CE08691 [U] KOG0999 Microtubule-associated protein Bicaudal-D
Length = 869
Score = 53.9 bits (128), Expect = 1e-06
Identities = 40/174 (22%), Positives = 90/174 (50%), Gaps = 10/174 (5%)
Query: 500 EEKIQSIQAEIAELDAQMEQVRLE-HEEKLKLKQVEKSQALLETNVKHINAKGDLYKQTE 558
E +++ ++ +IA L + EQ + + H+ ++ + + LE + + A+ DL +
Sbjct: 3 ESELEKLRQDIAILTEKYEQAKEDIHKAANAGLELLRQKEDLEKRLAEMQAELDLARTEI 62
Query: 559 EIKNQTISDKEDKEVAHQTVQSEIDELLLLKDEVAKENQEHESKVEELTAELDNKTSALN 618
+ NQT+++ + ++ +SE++ L +E + + +E+ ++ +L A+L K L
Sbjct: 63 DKTNQTLAEYRSQH--QRSTRSELENEESLLEESSAKEEEYLQRIAKLEADLKKKEQELA 120
Query: 619 E------SLAKKDETNAEI-QALEEEKARLEQEIKEAQELHQQNVSKIESIDNK 665
E S+ KK + ALE+E+ +L E+KE +E Q+ +S+ ++ +
Sbjct: 121 EKKEELESIEKKHSKEIDSGAALEDERRKLRAELKETKEREQRLISEYSELEEE 174
Score = 50.8 bits (120), Expect = 9e-06
Identities = 45/190 (23%), Positives = 85/190 (44%), Gaps = 18/190 (9%)
Query: 471 QYDEDQHQAKLA-LYSKEQDERYETKAQEYEEKIQSIQAEIAELDAQMEQVRLEHEEKLK 529
Q ED H+A A L Q E E + E + ++ + EI + + + + R +H+ +
Sbjct: 22 QAKEDIHKAANAGLELLRQKEDLEKRLAEMQAELDLARTEIDKTNQTLAEYRSQHQRSTR 81
Query: 530 LKQVEKSQALLETNVKH-------INAKGDLYKQTEEIKNQTISDKEDKEVAHQTVQSEI 582
+ + L E++ K + DL K+ +E+ + KE+ E + EI
Sbjct: 82 SELENEESLLEESSAKEEEYLQRIAKLEADLKKKEQELAEK----KEELESIEKKHSKEI 137
Query: 583 DELLLLKDE------VAKENQEHESKVEELTAELDNKTSALNESLAKKDETNAEIQALEE 636
D L+DE KE +E E ++ +EL+ + L +++A + E ++L
Sbjct: 138 DSGAALEDERRKLRAELKETKEREQRLISEYSELEEENIGLQKTVANLRGSQVEYESLRI 197
Query: 637 EKARLEQEIK 646
+ RLE+ I+
Sbjct: 198 DNNRLEETIE 207
>Hs20070123 [Z] KOG1003 Actin filament-coating protein tropomyosin
Length = 284
Score = 53.5 bits (127), Expect = 1e-06
Identities = 65/237 (27%), Positives = 118/237 (49%), Gaps = 26/237 (10%)
Query: 465 SVYDKLQYDEDQHQAKLALYSKEQDERYETKAQEYEEKIQSIQAEIAELDAQMEQVRLE- 523
S+ KL+ ED+ L YS+ + E K + E+K +A++A L+ +++ V E
Sbjct: 45 SLQKKLKGTEDE----LDKYSEALKDAQE-KLELAEKKATDAEADVASLNRRIQLVEEEL 99
Query: 524 --HEEKL-----KLKQVEKSQALLETNVKHINAKGDLYKQTEEIKNQTISDKEDKEVAHQ 576
+E+L KL++ EK+ E +K I ++ K E+++ Q I KE K +A
Sbjct: 100 DRAQERLATALQKLEEAEKAADESERGMKVIESRAQ--KDEEKMEIQEIQLKEAKHIAED 157
Query: 577 TVQS--EIDELLLLKD---EVAKENQE-HESKVEELTAELDNKTSALNESLAKKDETNAE 630
+ E+ L++ + E A+E E E +V +L +L L +A +D+ + +
Sbjct: 158 ADRKYEEVARKLVIIESDLERAEERAELSEGQVRQLEEQLRIMDQTLKALMAAEDKYSQK 217
Query: 631 IQALEEEKARLEQEIKEAQ---ELHQQNVSKIE-SIDN-KEYLPKVNEINTEISSLL 682
EEE L ++KEA+ E +++V+K+E SID+ +E + E N + +L
Sbjct: 218 EDRYEEEIKVLSDKLKEAETRAEFAERSVTKLEKSIDDLEEKVAHAKEENLSMHQML 274
>7298332 [BD] KOG0996 Structural maintenance of chromosome protein 4
(chromosome condensation complex Condensin subunit C)
Length = 1409
Score = 53.5 bits (127), Expect = 1e-06
Identities = 57/309 (18%), Positives = 130/309 (41%), Gaps = 51/309 (16%)
Query: 435 GTVVPGDDAPVATPEDPELIVRTQEG----YVSKSVYDKLQYDEDQHQAKLALYSKEQDE 490
GT+ G P+ ++ +T E +S+ + +Q ++ QA++ Y +EQ
Sbjct: 754 GTMSGGGSRPIRGKMGTQVRTKTAESADSSQISQKALEDMQIQAEELQARVN-YCQEQQG 812
Query: 491 RYETKAQEYEEKIQSIQAEIAELDAQMEQVRLEHEEKLKLKQVEKSQALLETNVKHINAK 550
E + Q + +Q +AE L + + + LK + ++ + L +T +
Sbjct: 813 SLEREIQTLKNGLQRDEAEYKRLAVSITSLEQQMASNLKQCEAQRQRMLKKTTDERA--- 869
Query: 551 GDLYKQTEEIKNQTISDKEDKEVAHQTVQSEIDELLLLKDEVAKENQEH-ESKVEELTAE 609
K+ EE + E + A Q V S+I+E+ D + E+ + E+K++++ ++
Sbjct: 870 ---VKEREEQIEAAKQELEQAQFAEQAVSSQIEEIQNQYDTLRNESVKPVEAKIKKVNSQ 926
Query: 610 LDNKTS---ALNESLAKKDET-------------------------NAEIQALEEEKARL 641
++ + +LN LA D N + +E+K L
Sbjct: 927 IEKLAANVRSLNVGLATADRNITKITGNNNNLRENIKAAEEKLKSLNEDRNKAKEKKEEL 986
Query: 642 EQEIKEAQELHQ----------QNVSKIESIDNKEYLPKVNEINTEISSLLASLGLIQQE 691
E+EI+E++ + + + +I +NK + ++ EI+T++ + + ++ +
Sbjct: 987 EKEIEESEASIEGAKSQSSDIKKEIDEITKEENKRNIERI-EIDTKLQAAAGKMNKVKND 1045
Query: 692 IANQKVEFS 700
I + + +
Sbjct: 1046 IPGWQAQLA 1054
>ECU04g1000 [Z] KOG0161 Myosin class II heavy chain
Length = 1700
Score = 53.1 bits (126), Expect = 2e-06
Identities = 53/241 (21%), Positives = 107/241 (43%), Gaps = 41/241 (17%)
Query: 493 ETKAQEYEEKIQSIQAEIAELDAQMEQVRLEHE------EKLKLKQVEKSQALLETNVKH 546
E QEY + + ++ E++ ++ + L+ E E K +EK + L+ K
Sbjct: 850 EAMIQEYARMLDAEKSRREEVEDMLKAMSLKRELLEKSVEDEKRFSMEKDELLMALRYKS 909
Query: 547 INAKGDLYKQTEEI-------------KNQTISDKEDK---------EVAHQ--TVQSEI 582
+L K +E+ N+ E+K EV+ Q + +
Sbjct: 910 DETAQELEKARKEVFDGHEERKMWETRVNEVAIQLEEKDSEILRLRREVSEQKGALSQQE 969
Query: 583 DELLLLKDEVAKENQEHESKVEELTAELDNKTSALNESLAKKDETNAEIQALEEEKARLE 642
E+ L++EV + E ++ VE++ E D++ AL E + +KD AE++ + E R+E
Sbjct: 970 KEICSLREEVVSKLSEKDAMVEKMLRERDSEVQALKEKVKEKD---AEVERILEGMKRME 1026
Query: 643 QEIKEAQELHQQNVSKIES-----IDNKEYLPKVNEINTEISSLLASLGLIQQEIANQKV 697
+E +E + ++N S I+ ++ K + + E+ + +L L + E+ + +V
Sbjct: 1027 REGEERNRMLKENESTIDELRTRCLNMKRWKDEYAELREDYEALQKKL---KDEVEDMQV 1083
Query: 698 E 698
E
Sbjct: 1084 E 1084
Score = 52.8 bits (125), Expect = 2e-06
Identities = 52/239 (21%), Positives = 119/239 (49%), Gaps = 31/239 (12%)
Query: 487 EQDERYETKAQEYEEKIQSIQAEIAELDAQMEQV-----RLEHEEKLKLKQVEKSQALL- 540
E+D E +E + ++Q+++ ++ E DA++E++ R+E E + + + ++++++ +
Sbjct: 985 EKDAMVEKMLRERDSEVQALKEKVKEKDAEVERILEGMKRMEREGEERNRMLKENESTID 1044
Query: 541 ETNVKHINAK------GDLYKQTEEIKNQTISDKEDKEVAHQTVQSEIDELLLLKDEVAK 594
E + +N K +L + E ++ + + ED +V + + +EI ++ ++E+ +
Sbjct: 1045 ELRTRCLNMKRWKDEYAELREDYEALQKKLKDEVEDMQVENDRLHNEIRKISKEREELGR 1104
Query: 595 ------ENQEHE----SKVEELTAELDNKTSALNESLAKKDETNAEIQALEEEKAR-LEQ 643
++ E E SK+E+ EL + A+ L K+ + Q EK R LE+
Sbjct: 1105 MQKKLLDDLEFERNRGSKLEKAFQELRGEYEAVEGQLQKERQFRDSTQESLLEKTRGLER 1164
Query: 644 EIKEAQELHQQNVSKIESIDNKEYLPKVNEINTEISSLLASLGLIQQEIANQKVEFSSV 702
+K E ++ E + N++ + + +E+ EI L S EI +++ F+S+
Sbjct: 1165 RVKSLNEKLRR-----EEMANRQLMSEKDEMYREIHVLQQSK---LDEIFDREAGFNSI 1215
>CE27133 [Z] KOG0161 Myosin class II heavy chain
Length = 2003
Score = 53.1 bits (126), Expect = 2e-06
Identities = 48/229 (20%), Positives = 107/229 (45%), Gaps = 20/229 (8%)
Query: 468 DKLQYDEDQHQAKLALYSKEQDERYETKAQEYEEKIQSIQAEIAELDAQMEQVRLEHEEK 527
+K++ + + ++ LA K+ DE +E +K + + E EQ R + E+
Sbjct: 1370 EKIEKEVKEVKSLLAEARKKLDEENREVMEELRKKKEKELSAEKERADMAEQAR-DKAER 1428
Query: 528 LKLKQVEKSQALLETNVKHINAKGDLYK-------QTEEIKNQTISDKEDKEVAHQTVQS 580
K K +++++ + + + A ++ + Q E +N T+ ++++++AHQ ++
Sbjct: 1429 AKKKAIQEAEDVQKELTDVVAATREMERKMRKFDQQLAEERNNTLLAQQERDMAHQMLRD 1488
Query: 581 EIDELLLLKDEVAKENQ---EHESKVEELTAELDNKTSALNESLAKKDETNAEIQALEEE 637
+ L+L +E++++ + E L E+DN S KD+ + LE+
Sbjct: 1489 AETKALVLSNELSEKKDIVDQLEKDKRTLKLEIDNLAST-------KDDAGKNVYELEKT 1541
Query: 638 KARLEQEIKEAQELHQQNVSKIESIDNKEYLPKVN--EINTEISSLLAS 684
K RL++E+ A++ + ++ D+ +VN + +E LAS
Sbjct: 1542 KRRLDEELSRAEQQIIELEDALQLADDARSRVEVNMQAMRSEFERQLAS 1590
Score = 52.8 bits (125), Expect = 2e-06
Identities = 49/211 (23%), Positives = 96/211 (45%), Gaps = 25/211 (11%)
Query: 473 DEDQHQAKLALYSKEQDERY---ETKAQEYEEKIQSIQAEIAELDAQMEQVRLEH-EEKL 528
DE++ + KL L + R E + E E+ + E L+ + E + +E
Sbjct: 971 DEERSRQKLLLEKNSIESRLKELEAQGLELEDSGNKLSKEKKALEERCEDLSSRLIDEVE 1030
Query: 529 KLKQVEKSQALLETNVKHINAKGDLYKQT----------------EEIKNQTISDKEDKE 572
+ KQ+ K++A LE V IN + + KQ EE ++ ++ +E
Sbjct: 1031 RSKQLVKAKARLEATVAEINDELEKEKQQRHNAETARRAAETQLREEQESCLEKTRKAEE 1090
Query: 573 VAHQTV--QSEIDELLLLKDEVAKENQEHESKVEELTAELDNKTSALNESLAKKDETNAE 630
+ +Q + +SE+ ++ + DE Q+ E ++ E+ A+LD+ N+ A + +
Sbjct: 1091 LTNQLMRKESELSQISIRNDEELAARQQLEREIREIRAQLDDAIEETNKEKAARQKAEKA 1150
Query: 631 IQALEEEKARLEQEIKEAQE---LHQQNVSK 658
+ + EE +QE++E+ + LH Q +K
Sbjct: 1151 RRDMAEELESYKQELEESNDKTVLHSQLKAK 1181
>CE22238 [S] KOG0992 Uncharacterized conserved protein
Length = 734
Score = 53.1 bits (126), Expect = 2e-06
Identities = 52/255 (20%), Positives = 117/255 (45%), Gaps = 18/255 (7%)
Query: 452 ELIVRTQEGYVSKSVYDKLQYDEDQHQAKLALYSKEQDERYETKAQEYEEKIQSIQAE-- 509
+LI + ++ + KLQ + + +L S+ ER T E K + E
Sbjct: 255 QLIQAKDDKHIIQQYEVKLQTSTAELERRLR-ESEHDVERLRTSQLEMATKFEEASRENT 313
Query: 510 --IAELDAQMEQVRLEHEEKLKLKQVEKSQALLETNVKHINAKGDLYKQTEEIKNQTISD 567
++++D +Q+ LE + + K E+ L+ + + ++TE+ + D
Sbjct: 314 DLLSKIDILQDQLSLEEDRR---KLCEEQIDRLKGVESFVESSSHRIEETEKERETAEED 370
Query: 568 KEDKEVAHQTVQSEIDELLLLKDEVAKENQEHESKVEELTAELDNKTSALNESLAKKDET 627
+E E+ + +++++L L E+ + N E + K+++ + + S + E L + T
Sbjct: 371 REQAELEAAEYREQVEKMLKLTQELTERNMELQRKLKDEEGKNTSHNSTI-EKLQVELTT 429
Query: 628 NAEI-QALEEEKARLEQEIKEAQELHQQNVSKIESIDNKEYLPKVNEINTEISSLLASLG 686
+ E+ ++ EE ++ +E++ + Q+ V+ +ES++ Y K +E + ++ A L
Sbjct: 430 SLELCKSFEETNLKISEELENLKTEMQKPVT-LESLEENFYRDKYDEASRKLEQTEAKL- 487
Query: 687 LIQQEIANQKVEFSS 701
A +K FS+
Sbjct: 488 ------AEEKNNFSA 496
>CE03665 [Z] KOG0161 Myosin class II heavy chain
Length = 1968
Score = 53.1 bits (126), Expect = 2e-06
Identities = 58/229 (25%), Positives = 111/229 (48%), Gaps = 32/229 (13%)
Query: 468 DKLQYDEDQHQAKLALYSKEQDERYETKAQEYEEKIQSIQAEIAELDAQMEQVRLEHEEK 527
++LQ D+ +A L E E+KA + ++ I+AEI + A+ E+ E+ K
Sbjct: 1554 EELQRGLDEAEAAL--------ESEESKALRCQIEVSQIRAEIEKRIAEKEE-EFENHRK 1604
Query: 528 LKLKQVEKSQALLETNVKHINAKGDLYKQTEEIKN-----QTISDKEDK--EVAHQTVQS 580
+ + ++ QA L++ K AK +L++ ++++ + D +K E A + ++
Sbjct: 1605 VHQQTIDSIQATLDSETK---AKSELFRVKKKLEADINELEIALDHANKANEDAQKNIRR 1661
Query: 581 EIDELLLLKDEVAKENQEHESKVEELTAELDNKTSALNESLAKKDETNAEIQALEEEKAR 640
+D++ L+ V +E + E E L A A E ++E +++ALE +
Sbjct: 1662 YLDQIRELQQTVDEEQKRREEFREHLLAAERKLAVAKQE----QEELIVKLEALERARRV 1717
Query: 641 LEQEIKEAQ----ELHQQNVSKI---ESIDNKEYL--PKVNEINTEISS 680
+E +KE Q EL+ QNV+ +DN+ L + E +TE+S+
Sbjct: 1718 VESSVKEHQEHNNELNSQNVALAAAKSQLDNEIALLNSDIAEAHTELSA 1766
>Hs4758648 [Z] KOG0240 Kinesin (SMY1 subfamily)
Length = 963
Score = 52.8 bits (125), Expect = 2e-06
Identities = 55/220 (25%), Positives = 109/220 (49%), Gaps = 32/220 (14%)
Query: 476 QHQAKLALYSKEQDERYETKAQEYEEKIQSIQAEIAELDAQ--MEQVRLEHEEKLK---- 529
QH+AK+ + E + E K ++ EE + ++ E+ +L AQ + ++ EH K++
Sbjct: 638 QHEAKIKSLT-EYLQNVEQKKRQLEESVDALSEELVQLRAQEKVHEMEKEHLNKVQTANE 696
Query: 530 LKQV--EKSQALLETNVKHINAKGDLYKQTEEIKNQTISDKEDKEVAHQTVQSEIDELLL 587
+KQ ++ Q+ ET+ K I++ D E K + I+D +D+ +Q + E + L +
Sbjct: 697 VKQAVEQQIQSHRETHQKQISSLRD----EVEAKAKLITDLQDQ---NQKMMLEQERLRV 749
Query: 588 LKDEVAKENQEHESKVEELTAELDNKTSA------LNESLAKKDETNAEIQAL------- 634
+++ +QE K+ ELT D + A L E++AK+ +T ++ L
Sbjct: 750 EHEKLKATDQEKSRKLHELTVMQDRREQARQDLKGLEETVAKELQTLHNLRKLFVQDLAT 809
Query: 635 -EEEKARLEQEIKEAQELHQQNVSKIESIDNKEYLPKVNE 673
++ A ++ + +Q +S +E +N E L KV++
Sbjct: 810 RVKKSAEIDSDDTGGSAAQKQKISFLE--NNLEQLTKVHK 847
>7303561 [S] KOG4674 Uncharacterized conserved coiled-coil protein
Length = 2346
Score = 52.8 bits (125), Expect = 2e-06
Identities = 52/235 (22%), Positives = 108/235 (45%), Gaps = 35/235 (14%)
Query: 474 EDQHQAKLALYSKEQDERYETKAQEYEEKIQSIQAEIAELDAQME------QVRLEHEEK 527
E +H AKL KE +++ ++ E Q + EI L+ QM+ + +++
Sbjct: 1367 EREHLAKLLTAEKELNKK---QSDELTVLKQRMNTEIPMLNKQMQILDEARKKQVDEFTN 1423
Query: 528 LKLKQVEKSQALLETNVKHINAKGDLYKQTEEI--KNQTISDKEDKEVAHQTVQSEIDEL 585
LK ++Q ++E + + + +L K EE+ K++TI+DKE KE+ + + +
Sbjct: 1424 LKQNNTRQTQDIMELKNRLLQKEEELLKANEELETKDKTIADKETKELQLRKLAKRYKDF 1483
Query: 586 LLLKDEVAKENQEHESKVEELTAELDNKTSALNESLAKKDETNAEIQALEEEKARLEQEI 645
+ + + E AEL+ S L +E N +++AL++E ++ +E
Sbjct: 1484 YI--------GLQSQGGGTESAAELEKVRSEL-------EEVNNQLRALKDEHEKITKEC 1528
Query: 646 KEAQELHQQNVSKIESIDNKEYLPKVNEINTEISSLLASLGLIQQEIANQKVEFS 700
E ++ + S +EY K+++ L+ L + + ++ NQ+ F+
Sbjct: 1529 DEVKKRTEPETD--TSAIRQEYKAKLDK-------LVVDLTVARTDLVNQETTFA 1574
>7303132 [BD] KOG0933 Structural maintenance of chromosome protein 2
(chromosome condensation complex Condensin subunit E)
Length = 1179
Score = 52.8 bits (125), Expect = 2e-06
Identities = 56/222 (25%), Positives = 110/222 (49%), Gaps = 28/222 (12%)
Query: 467 YDKLQYDEDQHQAKLALYSKEQDERYETKAQEYEEKIQSIQAEIAELDAQMEQVRLEHEE 526
++K++ + D Q +L + ++ +T Q+ + +I+ ++ + L+ Q+ ++ E
Sbjct: 710 FNKMKENLDLRQHELTMC---ENRLAQTTFQQNQAEIEEMRERVKTLEQQI----IDSRE 762
Query: 527 KLKLKQVEKSQALLETNVKHINAKG----DLYKQTEEIK------NQTISDKEDKEVAHQ 576
K K Q + +++ K +AKG +L T EIK ++ ++ + +E +
Sbjct: 763 KQKTSQAK----IVDIEAKLADAKGYRERELNAATNEIKVTKQRAEKSRANWKKREQEFE 818
Query: 577 TVQSEIDELLLLKDEVAKENQEHESKVEELTAELDNKTSALNESLAKKDETNAEIQALEE 636
T+Q EI EL + K++QE +E+ AELD +N S A + T E QA++E
Sbjct: 819 TLQLEITELQKSIETAKKQHQEMIDNLEKFKAELD--ALKVNSSSAASEVTELE-QAIKE 875
Query: 637 EKARLEQEIKEAQELHQQNVSKIESI-DNKEYLPKVNEINTE 677
+K +L + K E+ Q V K + + +N+E +V + E
Sbjct: 876 QKDKLRDQNK---EMRNQLVKKEKMLKENQEIELEVKKKENE 914
>YJL074c [D] KOG0964 Structural maintenance of chromosome protein 3 (sister
chromatid cohesion complex Cohesin subunit SMC3)
Length = 1230
Score = 52.4 bits (124), Expect = 3e-06
Identities = 51/208 (24%), Positives = 90/208 (42%), Gaps = 25/208 (12%)
Query: 485 SKEQDERYETKAQEYE----------EKIQSIQAEIAELDAQMEQVRLEHEEKLKLKQVE 534
SKE+ ER E+ +E + ++ I I L+A++E + E L+ K E
Sbjct: 798 SKEEKERLESLTKEISAAHNKLNITSDALEGITTTIDSLNAELESKLIPQENDLESKMSE 857
Query: 535 KSQALLETNVKHINAKGDLYKQTEEIKNQTISDKEDKEVAHQTVQSEIDELLLLKDEVAK 594
A I D K+ + K E+ + TVQ EI+ L+ + K
Sbjct: 858 VGDAF-------IFGLQDELKELQLEKESVEKQHENAVLELGTVQREIESLIAEETNNKK 910
Query: 595 ENQEHESKVEELTAELDNKTSALNESLAKKDETNAEIQALEEEKARLEQEIKEAQELHQQ 654
++ ++ L +LDN ++ +++ KK L + L+Q I+E L +
Sbjct: 911 LLEKANNQQRLLLKKLDNFQKSVEKTMIKK-------TTLVTRREELQQRIREIGLLPED 963
Query: 655 N-VSKIESIDNKEYLPKVNEINTEISSL 681
V+ I + + L ++N++NTEIS L
Sbjct: 964 ALVNDFSDITSDQLLQRLNDMNTEISGL 991
>YHR023w [Z] KOG0161 Myosin class II heavy chain
Length = 1928
Score = 52.4 bits (124), Expect = 3e-06
Identities = 42/193 (21%), Positives = 92/193 (46%), Gaps = 37/193 (19%)
Query: 494 TKAQEYEEKIQSIQAEIAELDAQMEQVRLEHEEKLKLKQVEKSQALLETNVKHINAKGDL 553
T+ +++ E+I ++ ++ E++++ + LE + + + ++E +Q LL N + +
Sbjct: 861 TRTKKFNEQINKLKNDLQEMESKKKF--LEEKNQKTVNELENTQDLL-------NQEKEN 911
Query: 554 YKQTEEIKNQTISDKEDKEVAHQTVQSEIDELLLLKDEVAKENQEHESKVEEL------- 606
++ E + N+ + E T+Q + D+L+ KDE+++E E +EE
Sbjct: 912 LRKNESLLNRVKTSSE-------TLQKQFDDLVSEKDEISREKLEVAQNLEEAHQKIQGL 964
Query: 607 -------TAELDNKTSALNESLAKKDETNAEI-------QALEEEKARLEQEIKEAQELH 652
A L+ S NE + + + N +I ++E K +LE EIK +++
Sbjct: 965 QETIREREATLEKLHSKNNELIKQISDLNCDISKEQSSQSLIKESKLKLENEIKRLKDVI 1024
Query: 653 QQNVSKIESIDNK 665
+I+S ++K
Sbjct: 1025 NSKEEEIKSFNDK 1037
>SPAC1F3.06c [S] KOG4674 Uncharacterized conserved coiled-coil protein
Length = 1957
Score = 52.4 bits (124), Expect = 3e-06
Identities = 68/291 (23%), Positives = 129/291 (43%), Gaps = 46/291 (15%)
Query: 420 KKPESSTKVAANAAAGTVVPGDDAPVATPEDPELIVRTQEGYVSKSVYD-KLQYDEDQHQ 478
KK E ++ A T V D + D LI Q G + K++ D + + + +
Sbjct: 1303 KKMELDNRLTTTDAEFTKVVADLEKLQHEHDDWLI---QRGDLEKALKDSEKNFLRKEAE 1359
Query: 479 AKLALYSKEQDERYETKAQEYEEKIQSIQAEIAELDAQMEQVRLEHEEKLKLKQVEKSQA 538
++S E+ + ETK EIAEL +++E +L K +
Sbjct: 1360 MTENIHSLEEGKE-ETK------------KEIAELSSRLEDNQL---------ATNKLKN 1397
Query: 539 LLETNVKHINAKGDLYKQTEEI---KNQTISDKEDKEVAHQTVQSEIDELLLLKDEVAKE 595
L+ + I K D+ K+ E + +++S++ KE + ++E++ +L D+ +++
Sbjct: 1398 QLDHLNQEIRLKEDVLKEKESLIISLEESLSNQRQKESSLLDAKNELEHML---DDTSRK 1454
Query: 596 NQEHESKVEELTAELDNKTSALNESLAKKDETNAEIQALEEEKARLEQEIK----EAQEL 651
N K+E + + LD+K+ LA E +Q L E L + IK EA+E
Sbjct: 1455 NSSLMEKIESINSSLDDKSF----ELASAVEKLGALQKLHSESLSLMENIKSQLQEAKEK 1510
Query: 652 HQQNVSKIESIDNK------EYLPKVNEINTEISSLLASLGLIQQEIANQK 696
Q + S I+ +D++ Y K+N+ ++ I L ++ + +A +K
Sbjct: 1511 IQVDESTIQELDHEITASKNNYEGKLNDKDSIIRDLSENIEQLNNLLAEEK 1561
>Hs9055284 [Z] KOG0160 Myosin class V heavy chain
Length = 1742
Score = 52.4 bits (124), Expect = 3e-06
Identities = 45/184 (24%), Positives = 94/184 (50%), Gaps = 16/184 (8%)
Query: 480 KLALYSKEQDERYETKAQEYEEKIQSIQAEIAELDAQMEQVRLEHEEK---LKLKQVEKS 536
K A + + +E+ + EEK+ +Q +EL+ Q EQ++L+ +EK LK K +
Sbjct: 935 KAATHRRNYEEKGKRYRDAVEEKLAKLQKHNSELETQKEQIQLKLQEKTEELKEKMDNLT 994
Query: 537 QALLETNVKHINAKGDLYKQTEEIKNQTISDKEDKEVAHQTVQSEIDELLLLKDEVAKEN 596
+ L + +V+ + L +++ E+K Q + +QS +E+ LKDE K
Sbjct: 995 KQLFD-DVQKEERQRMLLEKSFELKTQDY---------EKQIQSLKEEIKALKDE--KMQ 1042
Query: 597 QEHESKVEELTAE-LDNKTSALNESLAKKDETNAEIQALEEEKARLEQEIKEAQELHQQN 655
+H + E +T++ L + + L++ + E EI+ L+ +K +E+ ++ + ++
Sbjct: 1043 LQHLVEGEHVTSDGLKAEVARLSKQVKTISEFEKEIELLQAQKIDVEKHVQSQKREMREK 1102
Query: 656 VSKI 659
+S+I
Sbjct: 1103 MSEI 1106
Score = 52.4 bits (124), Expect = 3e-06
Identities = 57/216 (26%), Positives = 105/216 (48%), Gaps = 26/216 (12%)
Query: 462 VSKSVYDKLQYDEDQHQAKLALYSKEQDERYETKAQEYEEKIQSIQAEIAEL-DAQMEQV 520
++K ++D +Q +E Q ++ +E K Q+YE++IQS++ EI L D +M+
Sbjct: 993 LTKQLFDDVQKEERQRMLL--------EKSFELKTQDYEKQIQSLKEEIKALKDEKMQLQ 1044
Query: 521 RLEHEEKLKLKQVEKSQALLETNVKHINAKGDLYKQTEEIKNQTISDKEDKEVAHQTVQ- 579
L E + ++ A L VK I+ + K+ E ++ Q I ++ + + ++
Sbjct: 1045 HLVEGEHVTSDGLKAEVARLSKQVKTIS---EFEKEIELLQAQKIDVEKHVQSQKREMRE 1101
Query: 580 --SEIDELLL-------LKDEVAKENQEHESKVEELTAELDN--KTSALNES--LAKKDE 626
SEI + LL ++ ++ E+ EH ++ EL + K + + ES ++KD
Sbjct: 1102 KMSEITKQLLESYDIEDVRSRLSVEDLEHLNEDGELWFAYEGLKKATRVLESHFQSQKDC 1161
Query: 627 TNAEIQALEEEKARLEQEIKEAQELHQQNVSKIESI 662
EI+AL + L QEI Q+L ++ ESI
Sbjct: 1162 YEKEIEALNFKVVHLSQEINHLQKLFREENDINESI 1197
>Hs7661992 [KRT] KOG4572 Predicted DNA-binding transcription factor interacts
with stathmin
Length = 1591
Score = 52.4 bits (124), Expect = 3e-06
Identities = 48/234 (20%), Positives = 114/234 (48%), Gaps = 17/234 (7%)
Query: 462 VSKSVYDKLQYDEDQHQAKLALYSKEQDERYETKAQEYEEKIQSIQAEIAELDAQMEQVR 521
+ K++ +++ + + ++L+ +++DE+ + ++YE IQ+++ + +L + EQ R
Sbjct: 1168 IEKNLKEQIIELQSKLDSELSALERQKDEKITQQEEKYEAIIQNLEKDRQKLVSSQEQDR 1227
Query: 522 LEHEEKLKLKQVEKSQ-ALLETNVKHINAKGDLYKQTEEIKNQTISDKEDKEVAHQTVQS 580
+ +KL ++ E Q AL E ++ + +L ++ + ++NQ K A + +
Sbjct: 1228 EQLIQKLNCEKDEAIQTALKEFKLEREVVEKELLEKVKHLENQIA-----KSPAIDSTRG 1282
Query: 581 EIDELLL-LKDEVAKENQEHESKVEELTAELDNKTSALNESLAKKDETNAEIQALEEEKA 639
+ L+ L++++ +E + ++EE + + + SL + +TN L EK
Sbjct: 1283 DSSSLVAELQEKLQEEKAKFLEQLEEQEKRKNEEMQNVRTSLIAEQQTNFN-TVLTREKM 1341
Query: 640 R-------LEQEIKEAQELHQQNVSKIESI--DNKEYLPKVNEINTEISSLLAS 684
R L ++K + +++ IES+ D L + ++ E+S L +S
Sbjct: 1342 RKENIINDLSDKLKSTMQQQERDKDLIESLSEDRARLLEEKKKLEEEVSKLRSS 1395
>CE27289 [K] KOG0963 Transcription factor/CCAAT displacement protein CDP1
Length = 452
Score = 52.4 bits (124), Expect = 3e-06
Identities = 52/207 (25%), Positives = 91/207 (43%), Gaps = 23/207 (11%)
Query: 480 KLALYSKEQDERYETKAQEYEEKI-QSIQAEIAELDAQMEQVRLEHEEKLKLKQVEKSQA 538
KLA EQD E E E+K Q + + EL A+ E+++ ++E
Sbjct: 152 KLAKLESEQDIFIENAVNEVEKKAEQELNDRLTELIAEKEKMKEQNE------------- 198
Query: 539 LLETNVKHINAKGDLYKQTEEIKNQTISDKEDKE-----VAHQTVQSEIDELLLLKDEVA 593
+LE N+ + +K ++ EI QT+ K+ E +A + + +++ L++ V+
Sbjct: 199 ILEKNMDSLESKNKDIQRKLEIAKQTVEQKDGLENEQLSIAMKDLADAKHKIVFLEERVS 258
Query: 594 KENQEHESKVEELTAELDNKTSALNESLAKKDETNAEIQALEEEKARLEQEIKEAQELHQ 653
+ E E E A +AL L +KD+ IQ L + R E E +
Sbjct: 259 QLENEAEKVNESKKAGNIEDIAALGSVLVQKDDV---IQQLTNDIKRHEASHVEELAKWK 315
Query: 654 QNVSKIESIDNKEYLPKVNEINTEISS 680
VS +E NK + ++NE+ ++ S
Sbjct: 316 LAVSAVEK-KNKTLIGELNELKNQLES 341
>CE27288_1 [K] KOG0963 Transcription factor/CCAAT displacement protein CDP1
Length = 464
Score = 52.4 bits (124), Expect = 3e-06
Identities = 52/207 (25%), Positives = 91/207 (43%), Gaps = 23/207 (11%)
Query: 480 KLALYSKEQDERYETKAQEYEEKI-QSIQAEIAELDAQMEQVRLEHEEKLKLKQVEKSQA 538
KLA EQD E E E+K Q + + EL A+ E+++ ++E
Sbjct: 152 KLAKLESEQDIFIENAVNEVEKKAEQELNDRLTELIAEKEKMKEQNE------------- 198
Query: 539 LLETNVKHINAKGDLYKQTEEIKNQTISDKEDKE-----VAHQTVQSEIDELLLLKDEVA 593
+LE N+ + +K ++ EI QT+ K+ E +A + + +++ L++ V+
Sbjct: 199 ILEKNMDSLESKNKDIQRKLEIAKQTVEQKDGLENEQLSIAMKDLADAKHKIVFLEERVS 258
Query: 594 KENQEHESKVEELTAELDNKTSALNESLAKKDETNAEIQALEEEKARLEQEIKEAQELHQ 653
+ E E E A +AL L +KD+ IQ L + R E E +
Sbjct: 259 QLENEAEKVNESKKAGNIEDIAALGSVLVQKDDV---IQQLTNDIKRHEASHVEELAKWK 315
Query: 654 QNVSKIESIDNKEYLPKVNEINTEISS 680
VS +E NK + ++NE+ ++ S
Sbjct: 316 LAVSAVEK-KNKTLIGELNELKNQLES 341
>SPAC664.10 [Z] KOG0239 Kinesin (KAR3 subfamily)
Length = 817
Score = 52.0 bits (123), Expect = 4e-06
Identities = 42/177 (23%), Positives = 81/177 (45%), Gaps = 24/177 (13%)
Query: 474 EDQHQAKLALYSKEQDERYETKAQEYEEKIQSIQAEIAELDAQMEQVRLEHEEKLKLKQV 533
E QHQA+L ++ +++ + EY+ ++QS + + +++++ E+E K+ Q
Sbjct: 271 ELQHQAELQDFASNIEQKANSLIMEYKNELQSAEEHFSH---KIKELTSENELKISRLQE 327
Query: 534 EKSQALLETNVKHINAKGDLYKQTEEIKNQTISDKEDKEVAHQTVQSEIDELLLLKDEVA 593
EK L + ++ + Q + +K D E + +QS I L
Sbjct: 328 EKDSLLKKV------------QEGASLAMQRVQNKHDLE--KKRLQSAIQPL-------Q 366
Query: 594 KENQEHESKVEELTAELDNKTSALNESLAKKDETNAEIQALEEEKARLEQEIKEAQE 650
+EN + ++E+L EL ++T + D+ +A +Q LE LE IK +E
Sbjct: 367 EENNSLKQQIEQLQRELASETVVKENLKSSLDQQSANVQKLESTNRALESTIKTLEE 423
>Hs4758956 [TZ] KOG3632 Peripheral benzodiazepine receptor PRAX-1
Length = 1857
Score = 52.0 bits (123), Expect = 4e-06
Identities = 60/257 (23%), Positives = 113/257 (43%), Gaps = 33/257 (12%)
Query: 444 PVATPEDPELIVRTQEGYVSKSVYDKLQYDEDQHQAKLALYSKEQDERYETKAQEYEEKI 503
P + P P L R G + + ED + L E+++R + E +K
Sbjct: 291 PPSWPPGPALQARA--GAPAPGAPGEATPQEDADNLPVILGEPEKEQRVQQLESELSKKR 348
Query: 504 QSIQAEIAELDAQMEQVRLEHEEKLKLKQVEKSQALLETNVKHINAKGDLYKQTE----E 559
+ + E E +A+ +Q R E E +L+L+Q + A L ++ + +Q E E
Sbjct: 349 K--KCESLEQEARKKQRRCE-ELELQLRQAQNENARLVEENSRLSGRATEKEQVEWENAE 405
Query: 560 IKNQTISDKEDKEVA---HQTVQSEIDELLLLKDEVAKENQEHESKVEELTAELDNKTSA 616
++ Q + ++++ A Q +QS+++ L ++V K +E + ++L E + +
Sbjct: 406 LRGQLLGVTQERDSALRKSQGLQSKLESL----EQVLKHMREVAQRRQQLEVEHEQARLS 461
Query: 617 LNESLAKKDETNAEIQALEEEKARLEQEIKEAQELHQQNVSKIES-IDNKEYLPKVNEIN 675
L E +EE RL+Q EAQ H+ V +ES +D+ + +V E+
Sbjct: 462 LREK--------------QEEVRRLQQAQAEAQREHEGAVQLLESTLDSMQ--ARVRELE 505
Query: 676 TEISSLLASLGLIQQEI 692
+ S L+ QE+
Sbjct: 506 EQCRSQTEQFSLLAQEL 522
>CE27954 [Z] KOG0613 Projectin/twitchin and related proteins
Length = 3484
Score = 52.0 bits (123), Expect = 4e-06
Identities = 71/286 (24%), Positives = 121/286 (41%), Gaps = 39/286 (13%)
Query: 417 KRSKKPESSTKVAANAAAGTV-----------------VPGDDAPVATPEDPELIVRTQE 459
K+ K+ + K+ A AA T V DDA E + + E
Sbjct: 1002 KKQKETDEKLKLDAEIAAKTKQEADEKSKLDAQEKIKKVSEDDAARKEKELNDKLKLESE 1061
Query: 460 GYVSKSVYDKLQYDEDQHQAKLALY---SKEQDERYETKAQEYEEKIQSIQAEIAELDAQ 516
K+ DKL+ +E Q QAK A +K+Q E+ E + E + AE EL+ Q
Sbjct: 1062 IATKKASADKLKLEE-QAQAKKAAEVEAAKKQKEKDEQLKLDTEAASKKAAAEKLELEKQ 1120
Query: 517 MEQVRLEHEEKLKLKQVEKSQALLETNVKHINAKGDLYKQTEEIKNQTISD--KEDKEVA 574
+ + + +K ++ + LE N K K + +++ QT+ + K D +
Sbjct: 1121 AQIKKAAGADAVKKQKELDEKNKLEANKKSAAGKLKIEEESAAKSKQTVEEQAKLDAQTK 1180
Query: 575 HQTVQSEIDELLLLKDEVAKENQEHESKVEELTAE--LDNKTSALNESLAKKDETNAEI- 631
+T + + L KDE + + E + V+E + L KT + S+++K ET+ +
Sbjct: 1181 AKTAEKQTK---LEKDEKSTKESESKETVDEKPKKKVLKKKTEKSDSSISQKSETSKTVV 1237
Query: 632 -----QALEEEK----ARLEQEIKEAQELHQQNVSKIESIDNKEYL 668
E +K AR ++E E Q+L + +K +S D K L
Sbjct: 1238 ESAGPSESETQKVADAARKQKETDEKQKLEAEITAK-KSADEKSKL 1282
>7296430 [TV] KOG4297 C-type lectin
Length = 800
Score = 52.0 bits (123), Expect = 4e-06
Identities = 49/220 (22%), Positives = 113/220 (51%), Gaps = 16/220 (7%)
Query: 458 QEGYVSKSVYDKLQYDEDQHQAKLALYSKEQDERYETKAQEYEEKIQSIQAEIAELDAQM 517
++ + + +K +D + +LA +E+ +A+ EE Q + E D +
Sbjct: 553 RQNHAKRLAEEKRLHDLYAERIRLANTEREKQLAEAHEAKRLEELKLQEQLKKQE-DERQ 611
Query: 518 EQVRLEHEE---KLKLKQVEKSQALLETNVKHINAKGDLYKQTEEIKNQTISDKEDKEVA 574
EQ+R E EE +L+L+++E+++ E +K ++ + ++ EE K Q + +E A
Sbjct: 612 EQIRREQEEEEKRLELERLEEARRFEEKELKRLHEEN---QRREEQKLQREREIALREAA 668
Query: 575 HQTVQSEIDELLLLKDEVAKENQEHESKVEE--LTAELDNKTSALNESLAKKDETNAEIQ 632
+ + E + +L+ EVA+E ++ + ++E+ AE K E A++ + + +
Sbjct: 669 EKKLAEEEE---MLRKEVAEEERKVKQRLEDEMRQAEEARKAKEAEERAAEEAKAAEQKR 725
Query: 633 ALEEEKARLEQEIK-EAQELHQQNVSKIESI---DNKEYL 668
+E K + ++E+K + +E ++ V++I ++ D K+++
Sbjct: 726 RVEAAKKKADEEVKAKLEEKRREYVTRISALSPEDQKKFI 765
>Hs4758650 [Z] KOG0240 Kinesin (SMY1 subfamily)
Length = 957
Score = 51.6 bits (122), Expect = 5e-06
Identities = 48/238 (20%), Positives = 110/238 (46%), Gaps = 23/238 (9%)
Query: 452 ELIVRTQEGYVSKSVYDKLQYDEDQHQ-----AKLALYSKEQDERYETKAQEYEEKIQSI 506
E +++ Y+ + Q +E Q AKL K + ++ K +E+ ++Q
Sbjct: 637 EAKIKSLTDYMQNMEQKRRQLEESQDSLSEELAKLRAQEKMHEVSFQDKEKEHLTRLQDA 696
Query: 507 QAEIAELDAQMEQVRLEHEEKLKLKQVEKSQALLETNVKHINAKGDLYKQTEEIKNQTIS 566
+ L+ QME R H+ KQ+ + + +E K I+ DL ++ + + + S
Sbjct: 697 EEMKKALEQQMESHREAHQ-----KQLSRLRDEIEEKQKIIDEIRDLNQKLQLEQEKLSS 751
Query: 567 DKEDKEVAHQTVQSEIDELLLLKDEVAKENQEHESKVEELTAEL-----------DNKTS 615
D ++ Q + ++++LLLL D+ + ++ + E ++ EL + T+
Sbjct: 752 DYNKLKIEDQEREMKLEKLLLLNDKREQAREDLKGLEETVSRELQTLHNLRKLFVQDLTT 811
Query: 616 ALNESLAKKDETNAEIQALEEEKARLEQEIKEAQELHQQNVSKIESIDNKEYLPKVNE 673
+ +S+ ++ A +++ + LE +++ ++H+Q V ++ D + LPK+ +
Sbjct: 812 RVKKSVELDNDDGGGSAAQKQKISFLENNLEQLTKVHKQLVR--DNADLRCELPKLEK 867
>YFR016c [S] KOG1181 FOG: Low-complexity
Length = 1233
Score = 51.2 bits (121), Expect = 7e-06
Identities = 56/240 (23%), Positives = 111/240 (45%), Gaps = 18/240 (7%)
Query: 441 DDAPVATPEDPELI-VRTQEGYVS--KSVYDKLQYDEDQHQAKLALYSKEQDERYETKAQ 497
+DA V E E I V+ + G + K + +++ ++A SKE ETK
Sbjct: 863 EDAEVENSEKTEFIKVKAELGNLDAPKEAEVTAELNKENEDVEVAATSKED---IETKCS 919
Query: 498 E-YEEKIQS---IQAEIAELDAQMEQVRLEHEEKLKLKQVEKSQALLETNVKHINAKGDL 553
E E I+ +AE+++ DA+ E+ E K+ + K + + IN +
Sbjct: 920 EPAETPIEDGTCTEAEVSKKDAEAVTKEDENMENSKIAEALKD-VTGDQEIDDINISDEF 978
Query: 554 YKQTE--EIKNQTISDK--EDKEVAHQTVQSEID-ELLLLKDEVAKENQEHESKVEELTA 608
+ E E++ Q I D EDKE+ + + E L++++ + +E E + + EE++
Sbjct: 979 QRTVELPELEKQDIKDNKGEDKELEVEETEKETSLPDLVVEENITEEKNEIKQEEEEVSQ 1038
Query: 609 ELDNKTSALNESLAKKDETNAEIQALEE--EKARLEQEIKEAQELHQQNVSKIESIDNKE 666
N+T ++++ DE E Q+ E +KA + K+ + + + +++ +D+ E
Sbjct: 1039 LDFNETESISKEAPNNDENGFEDQSTRENPKKASADDIFKDILDETNEFLEQLKIVDDSE 1098
>Hs4826808 [Z] KOG0240 Kinesin (SMY1 subfamily)
Length = 1032
Score = 51.2 bits (121), Expect = 7e-06
Identities = 44/189 (23%), Positives = 90/189 (47%), Gaps = 19/189 (10%)
Query: 490 ERYETKAQEYEEKIQSIQAEIAELDAQMEQVR----LEHEEKLKLKQVEKSQALLETNVK 545
E+++ K ++ +EK ++ + IA+L+A++ + R + E+L ++ L E
Sbjct: 340 EQWKKKYEKEKEKTKAQKETIAKLEAELSRWRNGENVPETERLAGEEAALGAELCEETPV 399
Query: 546 HIN-------AKGDLYKQTEEIKN--QTISDKEDKEVAHQTVQSEIDELLLLKDEVAKEN 596
+ N A + K EEI+ + + DK+D+ + ++ + +L ++E+
Sbjct: 400 NDNSSIVVRIAPEERQKYEEEIRRLYKQLDDKDDEINQQSQLIEKLKQQMLDQEELLVST 459
Query: 597 QEHESKVEELTAELDNKTSALNESLAKKDETNAEIQALEEEKARLEQEIKEAQELHQQNV 656
+ KV+ + L + E+ A KDE +QALEE +Q+ +E +E QQN
Sbjct: 460 RGDNEKVQRELSHLQS------ENDAAKDEVKEVLQALEELAVNYDQKSQEVEEKSQQNQ 513
Query: 657 SKIESIDNK 665
++ + K
Sbjct: 514 LLVDELSQK 522
>7299993 [Z] KOG1003 Actin filament-coating protein tropomyosin
Length = 284
Score = 51.2 bits (121), Expect = 7e-06
Identities = 43/194 (22%), Positives = 95/194 (48%), Gaps = 14/194 (7%)
Query: 485 SKEQDERYETKAQEYEEKIQSIQAEIAELDAQMEQVRLEHEEKLKLKQVEKSQALLET-- 542
+KEQ E+ T+ +E E+ + + ++E+A + +++Q+ E EK + + Q LLE
Sbjct: 60 AKEQLEKANTELEEKEKLLTATESEVATQNRKVQQIE-EDLEKSEERSTTAQQKLLEATQ 118
Query: 543 ----NVKHINAKGDLYKQTEEIKNQTISDKEDKEVAHQTVQSEIDE----LLLLKD--EV 592
N + + +Q EE +Q + ++ + + ++ DE L ++D EV
Sbjct: 119 SADENNRMCKVLENRSQQDEERMDQLTNQLKEARMLAEDADTKSDEVSRKLAFVEDELEV 178
Query: 593 AKEN-QEHESKVEELTAELDNKTSALNESLAKKDETNAEIQALEEEKARLEQEIKEAQEL 651
A++ + ESK+ EL EL ++L +++ N ++ + E L ++KEA++
Sbjct: 179 AEDRVRSGESKIMELEEELKVVGNSLKSLEVSEEKANQRVEEFKREMKTLSIKLKEAEQR 238
Query: 652 HQQNVSKIESIDNK 665
+ +++ + +
Sbjct: 239 AEHAEKQVKRLQKE 252
>SPAP4C9.01c [L] KOG0962 DNA repair protein RAD50 ABC-type ATPase/SMC
superfamily
Length = 666
Score = 50.8 bits (120), Expect = 9e-06
Identities = 48/185 (25%), Positives = 90/185 (47%), Gaps = 11/185 (5%)
Query: 495 KAQEYEEKIQSIQAEIAELDAQMEQVRLEHEEKLKLKQVEKSQALLETNVKHINAKGDLY 554
K Q + I +++ EI +D + E +R+E + +++ A E K + +G L
Sbjct: 154 KLQLLVKDISNLEEEIRTIDRETEVLRIELPSSIAHHNLDEIYAERE---KLLEKRGYLR 210
Query: 555 KQTEEIKNQTISDKEDKEVAHQTVQSEIDELLLLK-DEVAKENQEHESKVEELTAELDNK 613
KQ E K + S K K++ + + +L L K + E ++ E + + + + D +
Sbjct: 211 KQIERTKLEETSFK--KKIDDAVLANNEQKLKLTKLNFQVNELEQLEKDINKSSEDCDLQ 268
Query: 614 TSALNESLAKKDETNAEIQALEEEKARLEQEIKEAQELHQQNVSKIESIDNKEYLPKVNE 673
L E +K+ + LE E +LE +I QE+ Q+ S+ E ++ EYL ++NE
Sbjct: 269 KKKLLEVSSKQGSQAPFLNELESEYEKLEADI---QEMAQK--SRTEILEANEYLHQLNE 323
Query: 674 INTEI 678
N+E+
Sbjct: 324 WNSEL 328
>Hs4502443 [Z] KOG0516 Dystonin GAS (Growth-arrest-specific protein) and related
proteins
Length = 2649
Score = 50.8 bits (120), Expect = 9e-06
Identities = 55/234 (23%), Positives = 113/234 (47%), Gaps = 28/234 (11%)
Query: 472 YDEDQHQAKLALYSKEQDERYETKAQEYEEKIQSIQAE------IAELDAQMEQVRLEHE 525
+ +++ +L + ++ D E + +E+ +Q+I+AE I L+ ++E+ E
Sbjct: 1511 FRDEKELERLQICQRKSDHLKEQFEKSHEQLLQNIKAEKENNDKIQRLNEELEKSN-ECA 1569
Query: 526 EKLKLKQVEKSQALLETNV--KHINAKGD---LYKQT-----EEIKNQTISDKED----K 571
E LK K E ++ ET + + I A+ + L KQT E +K Q K+
Sbjct: 1570 EMLKQKVEELTRQNNETKLMMQRIQAESENIVLEKQTIQQRCEALKIQADGFKDQLRSTN 1629
Query: 572 EVAHQTVQSEID---ELLLLKDEVAKENQEHESKVEELTAELDNKTSALNESLAKKDETN 628
E H+ ++E D ++ L++++AK ++ V E + D + + + + N
Sbjct: 1630 EHLHKQTKTEQDFQRKIKCLEEDLAKS----QNLVSEFKQKCDQQNIIIQNTKKEVRNLN 1685
Query: 629 AEIQALEEEKARLEQEIKEAQELHQQNVSKIESIDNKEYLPKVNEINTEISSLL 682
AE+ A +EEK R EQ+++ Q Q+ ++++ + ++ +L + E T +L
Sbjct: 1686 AELNASKEEKRRGEQKVQLQQAQVQELNNRLKKVQDELHLKTIEEQMTHRKMVL 1739
>Hs16554453 [O] KOG0978 E3 ubiquitin ligase involved in syntaxin degradation
Length = 975
Score = 50.8 bits (120), Expect = 9e-06
Identities = 55/293 (18%), Positives = 124/293 (41%), Gaps = 55/293 (18%)
Query: 434 AGTVVPGDDAPVATPEDPELIVRTQEGYVSKSVYDKLQYDEDQHQAKLALYSKEQD-ERY 492
+ T P D+ P+ +L ++ S+ ++++ D+ + + KE++ ER
Sbjct: 524 SSTEDPKDEPAELKPDSEDLSSQSSASKASQEDANEIKSKRDEEERERERREKERERERE 583
Query: 493 ETKAQEYEEKIQSIQAEIAELDAQMEQVRLEHEE------------KLKLKQVEKSQALL 540
K +E E + Q ++ E D+ ++ + +H++ K++LK+ ++SQ +
Sbjct: 584 REKEKEREREKQKLKESEKERDSAKDKEKGKHDDGRKKEAEIIKQLKIELKKAQESQKEM 643
Query: 541 ET--------------NVKHINAKGDLYKQTEEIKNQTISDKEDKEVAHQTVQSEIDELL 586
+ V+ + A+ + E+++ Q + D EDKE T ++ D L
Sbjct: 644 KLLLDMYRSAPKEQRDKVQLMAAEKKSKAELEDLR-QRLKDLEDKEKKENTKMADEDALR 702
Query: 587 ----------LLKDEVAKENQEHESKVEELTA------ELDNKTSALNESLAKKDETNAE 630
L+ ++A QE E+ + E+ ++ + L + L +KD+ N +
Sbjct: 703 KIRAVEEQIEYLQKKLAMAKQEEEALLSEMDVTGQAFEDMQEQNIRLMQQLREKDDANFK 762
Query: 631 IQA-----------LEEEKARLEQEIKEAQELHQQNVSKIESIDNKEYLPKVN 672
+ + L+EEK L ++ + + + ++ KE+L + N
Sbjct: 763 LMSERIKSNQIHKLLKEEKEELADQVLTLKTQVDAQLQVVRKLEEKEHLLQSN 815
>Hs13470092 [R] KOG1729 FYVE finger containing protein
Length = 1478
Score = 50.8 bits (120), Expect = 9e-06
Identities = 45/201 (22%), Positives = 87/201 (42%), Gaps = 27/201 (13%)
Query: 488 QDERYETKAQEYEEKIQSIQAEIAELDAQMEQVRLEHEEKLKLKQVEKSQALLETNVKHI 547
Q+ER + +AQ+ EE+++++Q E+++ E+ +LEH E L+ +
Sbjct: 856 QEERAD-EAQQREEELRALQEELSQAKCSSEEAQLEHAE-------------LQEQLHRA 901
Query: 548 NAKGDLYKQTEEIKNQTISDKEDKEVAHQTVQSEIDELLLLKDEVAKENQEHESKVEELT 607
N T E+ Q + +KE + + + EL K+ ++E + E +V
Sbjct: 902 NT------DTAELGIQVCALTVEKERVEEALACAVQELQDAKEAASREREGLERQV---- 951
Query: 608 AELDNKTSALNESLAKKDETNAEIQALEEEKARLEQEIKEAQELHQQNVSKIE---SIDN 664
A L + +L E L + L+ + A+ EQ + QE Q ++ ++ S +
Sbjct: 952 AGLQQEKESLQEKLKAAKAAAGSLPGLQAQLAQAEQRAQSLQEAAHQELNTLKFQLSAEI 1011
Query: 665 KEYLPKVNEINTEISSLLASL 685
+Y ++ E SL L
Sbjct: 1012 MDYQSRLKNAGEECKSLRGQL 1032
>At5g54670 [Z] KOG0239 Kinesin (KAR3 subfamily)
Length = 746
Score = 50.8 bits (120), Expect = 9e-06
Identities = 46/249 (18%), Positives = 109/249 (43%), Gaps = 32/249 (12%)
Query: 475 DQHQAKLALYSKEQDERYETKAQEYEEKIQSIQAEIA----ELDAQMEQVRLEHEEKLKL 530
++H + + K ++E +E + +S+Q ++A E A + + E E +L +
Sbjct: 107 EKHCVDMEVSLKNKEEELNMIIEELRKNFESVQVQLAREQTEKLAANDSLGKEKEARLSV 166
Query: 531 KQVE--------KSQALLETNVKHINAKGDLYKQTEEIKNQTISDKEDKEVAHQTVQSEI 582
++ + K+Q L+T + I + D+YK +E + ++ + +Q ++
Sbjct: 167 EKAQAGLTEELGKAQGDLQTANQRIQSVNDMYKLLQEYNSSL-------QLYNSKLQGDL 219
Query: 583 DELLLLKDEVAKENQEHESKVEELTAELDNKTSALNESLAKKDETNAEIQ----ALEEEK 638
DE E K ++ + + E L + SAL E LA + +I L E
Sbjct: 220 DE----AHETIKRGEKERTAIIENIGNLKGQFSALQEQLAASKASQEDIMKQKGELVNEI 275
Query: 639 ARLEQEIKEAQELHQQNVSKIESIDNK-----EYLPKVNEINTEISSLLASLGLIQQEIA 693
A L+ E+++ ++ +++ +++++ + ++ + E+ T SS + +Q +
Sbjct: 276 ASLKVELQQVKDDRDRHLVEVKTLQTEATKYNDFKDAITELETTCSSQSTQIRQLQDRLV 335
Query: 694 NQKVEFSSV 702
+ F +
Sbjct: 336 SDLSTFEKM 344
>At4g27180 [Z] KOG0239 Kinesin (KAR3 subfamily)
Length = 744
Score = 50.8 bits (120), Expect = 9e-06
Identities = 49/234 (20%), Positives = 104/234 (43%), Gaps = 29/234 (12%)
Query: 475 DQHQAKLALYSKEQDERYETKAQEYEEKIQSIQAEIA----ELDAQMEQVRLEHEEKLKL 530
++H A L + K ++E E + S+Q ++A E A E + E E ++ +
Sbjct: 98 EKHCADLEVNLKVKEEELNMVIDELRKNFASVQVQLAKEQTEKLAANESLGKEREARIAV 157
Query: 531 KQVE--------KSQALLETNVKHINAKGDLYKQTEEIKNQTISDKEDKEVAHQTVQSEI 582
+ ++ K+Q L+T + I A D+YK +E + ++ + +Q ++
Sbjct: 158 ESLQAAITEELAKTQGELQTANQRIQAVNDMYKLLQEYNSSL-------QLYNSKLQGDL 210
Query: 583 DELLLLKDEVAKENQEHESKVEELTAELDNKTSALNESLA----KKDETNAEIQALEEEK 638
DE E K ++ + + E L + AL + LA +D+ + L E
Sbjct: 211 DE----AHENIKRGEKERTGIVESIGNLKGQFKALQDQLAASKVSQDDVMKQKDELVNEI 266
Query: 639 ARLEQEIKEAQELHQQNVSKIESIDNKEYLPKVNEINTEISSLLASLGLIQQEI 692
L+ EI++ ++ +++++IE++ + K N+ I+ L + + +EI
Sbjct: 267 VSLKVEIQQVKDDRDRHITEIETLQAE--ATKQNDFKDTINELESKCSVQNKEI 318
>7303398 [R] KOG2579 Ficolin and related extracellular proteins
Length = 774
Score = 50.8 bits (120), Expect = 9e-06
Identities = 67/278 (24%), Positives = 117/278 (41%), Gaps = 31/278 (11%)
Query: 425 STKVAANAAAGTVVPGD------DAPVATPEDPELIVRTQEGYVSKSVYDKLQY-DEDQH 477
S + AA+G VV D DA V T E P ++ QE +S + L++ D+D+
Sbjct: 20 SVAFVSGAASGGVVLSDVNNMLRDAKVVTSEKP-VVHSKQETEAPESSVELLRFVDDDED 78
Query: 478 QAKLALYSKEQDERYETKAQEYEEKIQSIQAEIAELDAQMEQVRLEHEEKLKLKQVEKSQ 537
++ ++ E+K + ++ + Q L + + LEH + L+
Sbjct: 79 SEDISSIERQDGRTMESKKMADQVRLLTKQLNALMLRRREDYEMLEHNLRKSLR------ 132
Query: 538 ALLETNVKHINA--KGDLYKQTEEIKNQTISDKEDK-----EVAHQT---VQSEIDELLL 587
L TN ++A + +L + EE+ S +K E QT ++ ++ +L
Sbjct: 133 --LTTNANSVDADMRSELNQLREELAALRSSQSGNKERLTVEWLQQTISEIRKQLVDLQR 190
Query: 588 LKDEVAKENQEHESKVEELTAELDNKTSALNESLA----KKDETNAEIQALEEEKARLEQ 643
VA++ Q+ S E+L A + + L LA ++ +T +Q L EE + EQ
Sbjct: 191 TASNVAQDVQQRSSTFEDL-ATIRSDYQQLKLDLAAQRERQQQTEVYVQELREEMLQQEQ 249
Query: 644 EIKEAQELHQQNVSKIESIDNKEYLPKVNEINTEISSL 681
+ + A QQ K S + E E N E + L
Sbjct: 250 DFQHALVKLQQRTRKDGSSASVEEESGSQEANQEQTGL 287
Database: KOG eukaryal database 04/03
Posted date: Apr 14, 2003 1:07 PM
Number of letters in database: 30,389,216
Number of sequences in database: 60,738
Lambda K H
0.303 0.123 0.319
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 38,564,536
Number of Sequences: 60738
Number of extensions: 1451657
Number of successful extensions: 13008
Number of sequences better than 1.0e-05: 80
Number of HSP's better than 0.0 without gapping: 0
Number of HSP's successfully gapped in prelim test: 87
Number of HSP's that attempted gapping in prelim test: 11925
Number of HSP's gapped (non-prelim): 599
length of query: 871
length of database: 30,389,216
effective HSP length: 115
effective length of query: 756
effective length of database: 23,404,346
effective search space: 17693685576
effective search space used: 17693685576
T: 11
A: 40
X1: 17 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 43 (21.8 bits)