ORF STATUS Function Best COG Functional category Pathways and functional systems
r_klactIV4045.1 good O KOG3083 Posttranslational modification, protein turnover, chaperones Prohibitin
Only best alignment is shown:
BLASTP 2.2.3 [May-13-2002]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= r_klactIV4045.1 1372450 1372286 -55
(55 letters)
Database: KOG eukaryal database 04/03
60,738 sequences; 30,389,216 total letters
Searching..................................................done
Color Key for Alignment Scores: 
Score E
Sequences producing significant alignments: (bits) Value
YGR132c [O] KOG3083 Prohibitin 77 4e-15
At3g27280 [O] KOG3083 Prohibitin 50 6e-07
At5g40770 [O] KOG3083 Prohibitin 50 8e-07
SPAC1782.06c [O] KOG3083 Prohibitin 49 1e-06
At5g14300 [O] KOG3083 Prohibitin 47 6e-06
CE26775 [O] KOG3083 Prohibitin 44 4e-05
Hs4505773 [O] KOG3083 Prohibitin 44 5e-05
7298546 [O] KOG3083 Prohibitin 40 8e-04
Hs17463729 [O] KOG3083 Prohibitin 38 0.002
Hs17468096 [O] KOG3083 Prohibitin 34 0.033
At4g28510 [O] KOG3090 Prohibitin-like protein 34 0.033
At1g03860 [O] KOG3090 Prohibitin-like protein 34 0.043
At2g20530 [O] KOG3090 Prohibitin-like protein 33 0.056
At5g44140 [O] KOG3090 Prohibitin-like protein 32 0.16
Hs17487396 [O] KOG3083 Prohibitin 32 0.21
7302549 [O] KOG3090 Prohibitin-like protein 30 0.81
CE25680 [E] KOG3820 Aromatic amino acid hydroxylase 28 3.1
YGR231c [O] KOG3090 Prohibitin-like protein 26 9.0
Hs4506295 [T] KOG0792 Protein tyrosine phosphatase PTPMEG contai... 26 9.0
>YGR132c [O] KOG3083 Prohibitin
Length = 287
Score = 77.0 bits (188), Expect = 4e-15
Identities = 40/58 (68%), Positives = 47/58 (80%), Gaps = 3/58 (5%)
Query: 1 MSKAGDGLLLIRRLEASKEIAETLANSPNITYLPSKSSQGG---QDGTSNSLLLNIGR 55
++K GDGLLLIRRLEASK+IA+TLANS N+ YLPS+ S GG G+ NSLLLNIGR
Sbjct: 230 LAKVGDGLLLIRRLEASKDIAQTLANSSNVVYLPSQHSGGGNSESSGSPNSLLLNIGR 287
>At3g27280 [O] KOG3083 Prohibitin
Length = 279
Score = 50.1 bits (118), Expect = 6e-07
Identities = 29/54 (53%), Positives = 36/54 (65%), Gaps = 8/54 (14%)
Query: 2 SKAGDGLLLIRRLEASKEIAETLANSPNITYLPSKSSQGGQDGTSNSLLLNIGR 55
+KAG GL+ +RR+EAS+E+A TLA SPN+ YLP GGQ N LN GR
Sbjct: 234 AKAGMGLIELRRIEASREVAATLARSPNVAYLP-----GGQSMLFN---LNPGR 279
>At5g40770 [O] KOG3083 Prohibitin
Length = 277
Score = 49.7 bits (117), Expect = 8e-07
Identities = 23/37 (62%), Positives = 29/37 (78%)
Query: 2 SKAGDGLLLIRRLEASKEIAETLANSPNITYLPSKSS 38
+KAG GL+ +RR+EAS+EIA TLA SPN+ YLP S
Sbjct: 234 AKAGMGLIELRRIEASREIASTLARSPNVAYLPGGQS 270
>SPAC1782.06c [O] KOG3083 Prohibitin
Length = 282
Score = 48.9 bits (115), Expect = 1e-06
Identities = 25/54 (46%), Positives = 33/54 (60%), Gaps = 1/54 (1%)
Query: 1 MSKAGDGLLLIRRLEASKEIAETLAN-SPNITYLPSKSSQGGQDGTSNSLLLNI 53
+ KAG L+ IRRLE SKE+A LAN +TYLP + Q + + LLLN+
Sbjct: 227 LDKAGGALIQIRRLETSKEVATALANKGAQVTYLPFGAGSNAQSSSGSGLLLNV 280
>At5g14300 [O] KOG3083 Prohibitin
Length = 249
Score = 46.6 bits (109), Expect = 6e-06
Identities = 20/32 (62%), Positives = 28/32 (87%)
Query: 4 AGDGLLLIRRLEASKEIAETLANSPNITYLPS 35
AG GL+ +RR+EA++E+A TL+NSPN+ YLPS
Sbjct: 202 AGMGLIKLRRVEAAREVAITLSNSPNVVYLPS 233
>CE26775 [O] KOG3083 Prohibitin
Length = 275
Score = 43.9 bits (102), Expect = 4e-05
Identities = 18/33 (54%), Positives = 28/33 (84%)
Query: 2 SKAGDGLLLIRRLEASKEIAETLANSPNITYLP 34
+ AGDGL+ +R++EA++EIAE +A + N+TYLP
Sbjct: 232 ASAGDGLVELRKIEAAEEIAERMAKNKNVTYLP 264
>Hs4505773 [O] KOG3083 Prohibitin
Length = 272
Score = 43.5 bits (101), Expect = 5e-05
Identities = 20/38 (52%), Positives = 30/38 (78%)
Query: 1 MSKAGDGLLLIRRLEASKEIAETLANSPNITYLPSKSS 38
++ AGDGL+ +R+LEA+++IA L+ S NITYLP+ S
Sbjct: 228 LATAGDGLIELRKLEAAEDIAYQLSRSRNITYLPAGQS 265
>7298546 [O] KOG3083 Prohibitin
Length = 276
Score = 39.7 bits (91), Expect = 8e-04
Identities = 18/36 (50%), Positives = 27/36 (75%)
Query: 3 KAGDGLLLIRRLEASKEIAETLANSPNITYLPSKSS 38
+AGDGL+ +RR+EA+++IA L+ S + YLPS S
Sbjct: 230 EAGDGLVELRRIEAAEDIAYQLSRSRGVAYLPSGQS 265
>Hs17463729 [O] KOG3083 Prohibitin
Length = 396
Score = 38.1 bits (87), Expect = 0.002
Identities = 17/38 (44%), Positives = 28/38 (72%)
Query: 1 MSKAGDGLLLIRRLEASKEIAETLANSPNITYLPSKSS 38
++ +GD L+ + +LEA+++IA L+ S NITYLP+ S
Sbjct: 352 LATSGDSLMELSKLEAAEDIAHQLSGSRNITYLPAGRS 389
>Hs17468096 [O] KOG3083 Prohibitin
Length = 249
Score = 34.3 bits (77), Expect = 0.033
Identities = 17/38 (44%), Positives = 25/38 (65%)
Query: 1 MSKAGDGLLLIRRLEASKEIAETLANSPNITYLPSKSS 38
++ AGD L+ +R+LEA ++I L S NITYL + S
Sbjct: 205 LATAGDALIELRKLEAVEDITYQLLRSRNITYLRAGQS 242
>At4g28510 [O] KOG3090 Prohibitin-like protein
Length = 288
Score = 34.3 bits (77), Expect = 0.033
Identities = 18/45 (40%), Positives = 29/45 (64%), Gaps = 11/45 (24%)
Query: 9 LLIRRLEASKEIAETLANSPNITYLPSKSSQGGQDGTSNSLLLNI 53
+ +R++EA++EIA+T+ANS N YL +S+ LLLN+
Sbjct: 244 ITLRKIEAAREIAQTIANSANKVYL-----------SSDDLLLNL 277
>At1g03860 [O] KOG3090 Prohibitin-like protein
Length = 286
Score = 33.9 bits (76), Expect = 0.043
Identities = 18/45 (40%), Positives = 28/45 (62%), Gaps = 11/45 (24%)
Query: 9 LLIRRLEASKEIAETLANSPNITYLPSKSSQGGQDGTSNSLLLNI 53
+ +R++EA++EIA+T+A S N YL +SN LLLN+
Sbjct: 244 ITLRKIEAAREIAQTIAQSANKVYL-----------SSNDLLLNL 277
>At2g20530 [O] KOG3090 Prohibitin-like protein
Length = 286
Score = 33.5 bits (75), Expect = 0.056
Identities = 18/45 (40%), Positives = 28/45 (62%), Gaps = 11/45 (24%)
Query: 9 LLIRRLEASKEIAETLANSPNITYLPSKSSQGGQDGTSNSLLLNI 53
L +R++EA++EIA+T++ S N YL +SN LLLN+
Sbjct: 242 LTLRKIEAAREIAQTISRSANKVYL-----------SSNDLLLNL 275
>At5g44140 [O] KOG3090 Prohibitin-like protein
Length = 278
Score = 32.0 bits (71), Expect = 0.16
Identities = 13/30 (43%), Positives = 22/30 (73%)
Query: 6 DGLLLIRRLEASKEIAETLANSPNITYLPS 35
+ + +R++EA++EIA+T+A S N YL S
Sbjct: 241 EAFITLRKIEAAREIAQTIAKSANKVYLNS 270
>Hs17487396 [O] KOG3083 Prohibitin
Length = 376
Score = 31.6 bits (70), Expect = 0.21
Identities = 16/38 (42%), Positives = 26/38 (68%)
Query: 1 MSKAGDGLLLIRRLEASKEIAETLANSPNITYLPSKSS 38
++ A D L+ + +LEA+++IA L+ S NITY P+ S
Sbjct: 196 LATARDRLMELCKLEAAEDIAYQLSRSRNITYPPAGQS 233
>7302549 [O] KOG3090 Prohibitin-like protein
Length = 303
Score = 29.6 bits (65), Expect = 0.81
Identities = 18/51 (35%), Positives = 28/51 (54%), Gaps = 11/51 (21%)
Query: 3 KAGDGLLLIRRLEASKEIAETLANSPNITYLPSKSSQGGQDGTSNSLLLNI 53
K L +R+L A++ IA T+A+S N YL +++SL+LNI
Sbjct: 244 KQNPAYLKLRKLRAAQSIARTIASSQNKVYL-----------SADSLMLNI 283
>CE25680 [E] KOG3820 Aromatic amino acid hydroxylase
Length = 522
Score = 27.7 bits (60), Expect = 3.1
Identities = 10/41 (24%), Positives = 26/41 (63%)
Query: 9 LLIRRLEASKEIAETLANSPNITYLPSKSSQGGQDGTSNSL 49
++++ S++I++ +AN P+ T + ++ QDG+S ++
Sbjct: 80 IIVKSSRVSEDISKMIANLPDHTRIKHLETRDSQDGSSKTM 120
>YGR231c [O] KOG3090 Prohibitin-like protein
Length = 315
Score = 26.2 bits (56), Expect = 9.0
Identities = 10/27 (37%), Positives = 21/27 (77%)
Query: 11 IRRLEASKEIAETLANSPNITYLPSKS 37
++RL+ +++IA+ LA+SPN L +++
Sbjct: 268 LKRLDTARDIAKILASSPNRVILDNEA 294
>Hs4506295 [T] KOG0792 Protein tyrosine phosphatase PTPMEG contains FERM
domain
Length = 926
Score = 26.2 bits (56), Expect = 9.0
Identities = 11/34 (32%), Positives = 19/34 (55%)
Query: 4 AGDGLLLIRRLEASKEIAETLANSPNITYLPSKS 37
+G+ +LL+R + E L N P+ Y+P K+
Sbjct: 594 SGELMLLVRPNAVYDVVEEKLENEPDFQYIPEKA 627
Database: KOG eukaryal database 04/03
Posted date: Apr 14, 2003 1:07 PM
Number of letters in database: 30,389,216
Number of sequences in database: 60,738
Lambda K H
0.307 0.128 0.334
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 2,871,243
Number of Sequences: 60738
Number of extensions: 76891
Number of successful extensions: 217
Number of sequences better than 10.0: 19
Number of HSP's better than 10.0 without gapping: 19
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 196
Number of HSP's gapped (non-prelim): 19
length of query: 55
length of database: 30,389,216
effective HSP length: 31
effective length of query: 24
effective length of database: 28,506,338
effective search space: 684152112
effective search space used: 684152112
T: 11
A: 40
X1: 16 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.6 bits)