ORF STATUS Function Best COG Functional category Pathways and functional systems
r_klactIV4046 good O KOG3083 Posttranslational modification, protein turnover, chaperones Prohibitin
Only best alignment is shown:
BLASTP 2.2.3 [May-13-2002]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= r_klactIV4046 1373127 1372450 -226
(226 letters)
Database: KOG eukaryal database 04/03
60,738 sequences; 30,389,216 total letters
Searching..................................................done
Color Key for Alignment Scores: 
Score E
Sequences producing significant alignments: (bits) Value
YGR132c [O] KOG3083 Prohibitin 350 7e-97
SPAC1782.06c [O] KOG3083 Prohibitin 318 3e-87
Hs4505773 [O] KOG3083 Prohibitin 258 6e-69
7298546 [O] KOG3083 Prohibitin 258 6e-69
CE26775 [O] KOG3083 Prohibitin 254 9e-68
At3g27280 [O] KOG3083 Prohibitin 251 6e-67
At5g40770 [O] KOG3083 Prohibitin 249 3e-66
YGR231c [O] KOG3090 Prohibitin-like protein 248 5e-66
SPCC1322.16 [O] KOG3090 Prohibitin-like protein 239 2e-63
At1g03860 [O] KOG3090 Prohibitin-like protein 235 4e-62
At4g28510 [O] KOG3090 Prohibitin-like protein 233 2e-61
At2g20530 [O] KOG3090 Prohibitin-like protein 231 5e-61
Hs6005854 [O] KOG3090 Prohibitin-like protein 229 2e-60
7302549 [O] KOG3090 Prohibitin-like protein 229 3e-60
At5g44140 [O] KOG3090 Prohibitin-like protein 221 5e-58
At5g14300 [O] KOG3083 Prohibitin 199 3e-51
CE02883 [O] KOG3090 Prohibitin-like protein 198 4e-51
Hs17485621 [O] KOG3083 Prohibitin 187 1e-47
Hs17468096 [O] KOG3083 Prohibitin 186 2e-47
Hs17487396 [O] KOG3083 Prohibitin 174 7e-44
Hs22045430 [O] KOG3083 Prohibitin 164 7e-41
Hs16163999 [O] KOG3083 Prohibitin 160 2e-39
Hs17463729 [O] KOG3083 Prohibitin 156 2e-38
Hs18584047 [O] KOG3083 Prohibitin 137 2e-32
Hs22041974 [O] KOG3083 Prohibitin 106 2e-23
Hs17473006 [O] KOG3083 Prohibitin 69 7e-12
>YGR132c [O] KOG3083 Prohibitin
Length = 287
Score = 350 bits (899), Expect = 7e-97
Identities = 172/213 (80%), Positives = 199/213 (92%)
Query: 2 SRVADVMARIAIPVGLTVSAIQYSMYDVRGGHRAVIFDRLQGVQQAVIGEGTHFLVPWLQ 61
+++ DV+ ++A+P+G+ S IQYSMYDV+GG R VIFDR+ GV+Q V+GEGTHFLVPWLQ
Sbjct: 5 AKLIDVITKVALPIGIIASGIQYSMYDVKGGSRGVIFDRINGVKQQVVGEGTHFLVPWLQ 64
Query: 62 KSILFDVRTKPKNIATNTGTKDLQMVSLTLRVLHRPDVMQLPKIYQNLGIDYDERVLPSI 121
K+I++DVRTKPK+IATNTGTKDLQMVSLTLRVLHRP+V+QLP IYQNLG+DYDERVLPSI
Sbjct: 65 KAIIYDVRTKPKSIATNTGTKDLQMVSLTLRVLHRPEVLQLPAIYQNLGLDYDERVLPSI 124
Query: 122 GNEVLKAIVAQFDAAELITQREIVSQRIRAELSKRADEFHIKLEDVSITHMTFGQEFTKA 181
GNEVLK+IVAQFDAAELITQREI+SQ+IR ELS RA+EF IKLEDVSITHMTFG EFTKA
Sbjct: 125 GNEVLKSIVAQFDAAELITQREIISQKIRKELSTRANEFGIKLEDVSITHMTFGPEFTKA 184
Query: 182 VEQKQIAQQDAERARFLVEKAEQERKAAVIRAE 214
VEQKQIAQQDAERA+FLVEKAEQER+A+VIRAE
Sbjct: 185 VEQKQIAQQDAERAKFLVEKAEQERQASVIRAE 217
>SPAC1782.06c [O] KOG3083 Prohibitin
Length = 282
Score = 318 bits (816), Expect = 3e-87
Identities = 158/214 (73%), Positives = 192/214 (88%)
Query: 1 MSRVADVMARIAIPVGLTVSAIQYSMYDVRGGHRAVIFDRLQGVQQAVIGEGTHFLVPWL 60
M+ V + +AR AIP+G+ + +Q S+YDV GG RAV+FDRL GVQ+ V+ EGTHFL+PWL
Sbjct: 1 MAVVLERVARYAIPIGIGFTLLQSSIYDVPGGKRAVLFDRLSGVQKQVVQEGTHFLIPWL 60
Query: 61 QKSILFDVRTKPKNIATNTGTKDLQMVSLTLRVLHRPDVMQLPKIYQNLGIDYDERVLPS 120
QK+I++DVRT+P+NIAT TG+KDLQMVSLTLRVLHRP+V LP+IYQNLG+DYDERVLPS
Sbjct: 61 QKAIVYDVRTRPRNIATTTGSKDLQMVSLTLRVLHRPEVGMLPQIYQNLGLDYDERVLPS 120
Query: 121 IGNEVLKAIVAQFDAAELITQREIVSQRIRAELSKRADEFHIKLEDVSITHMTFGQEFTK 180
IGNE+LK++VAQFDAAELITQRE+VS +IR EL +RA EF I+LEDVSITHMTFG+EFTK
Sbjct: 121 IGNEILKSVVAQFDAAELITQREVVSAKIRQELVQRATEFGIRLEDVSITHMTFGKEFTK 180
Query: 181 AVEQKQIAQQDAERARFLVEKAEQERKAAVIRAE 214
AVE+KQIAQQ+AERARFLVE++EQER+A VIRAE
Sbjct: 181 AVERKQIAQQEAERARFLVEQSEQERQANVIRAE 214
>Hs4505773 [O] KOG3083 Prohibitin
Length = 272
Score = 258 bits (658), Expect = 6e-69
Identities = 120/213 (56%), Positives = 172/213 (80%)
Query: 2 SRVADVMARIAIPVGLTVSAIQYSMYDVRGGHRAVIFDRLQGVQQAVIGEGTHFLVPWLQ 61
++V + + + + + + + ++Y+V GHRAVIFDR +GVQ V+GEGTHFL+PW+Q
Sbjct: 3 AKVFESIGKFGLALAVAGGVVNSALYNVDAGHRAVIFDRFRGVQDIVVGEGTHFLIPWVQ 62
Query: 62 KSILFDVRTKPKNIATNTGTKDLQMVSLTLRVLHRPDVMQLPKIYQNLGIDYDERVLPSI 121
K I+FD R++P+N+ TG+KDLQ V++TLR+L RP QLP+I+ ++G DYDERVLPSI
Sbjct: 63 KPIIFDCRSRPRNVPVITGSKDLQNVNITLRILFRPVASQLPRIFTSIGEDYDERVLPSI 122
Query: 122 GNEVLKAIVAQFDAAELITQREIVSQRIRAELSKRADEFHIKLEDVSITHMTFGQEFTKA 181
E+LK++VA+FDA ELITQRE+VS+++ +L++RA F + L+DVS+TH+TFG+EFT+A
Sbjct: 123 TTEILKSVVARFDAGELITQRELVSRQVSDDLTERAATFGLILDDVSLTHLTFGKEFTEA 182
Query: 182 VEQKQIAQQDAERARFLVEKAEQERKAAVIRAE 214
VE KQ+AQQ+AERARF+VEKAEQ++KAA+I AE
Sbjct: 183 VEAKQVAQQEAERARFVVEKAEQQKKAAIISAE 215
>7298546 [O] KOG3083 Prohibitin
Length = 276
Score = 258 bits (658), Expect = 6e-69
Identities = 122/207 (58%), Positives = 167/207 (79%)
Query: 8 MARIAIPVGLTVSAIQYSMYDVRGGHRAVIFDRLQGVQQAVIGEGTHFLVPWLQKSILFD 67
+ ++ + V + + ++Y+V GGHRAVIFDR G+++ V+GEGTHF +PW+Q+ I+FD
Sbjct: 9 IGQMGLGVAVLGGVVNSALYNVEGGHRAVIFDRFTGIKENVVGEGTHFFIPWVQRPIIFD 68
Query: 68 VRTKPKNIATNTGTKDLQMVSLTLRVLHRPDVMQLPKIYQNLGIDYDERVLPSIGNEVLK 127
+R++P+N+ TG+KDLQ V++TLR+L+RP QLPKIY LG DYDERVLPSI EVLK
Sbjct: 69 IRSQPRNVPVITGSKDLQNVNITLRILYRPIPDQLPKIYTILGQDYDERVLPSIAPEVLK 128
Query: 128 AIVAQFDAAELITQREIVSQRIRAELSKRADEFHIKLEDVSITHMTFGQEFTKAVEQKQI 187
A+VAQFDA ELITQRE+VSQR+ EL+ RA +F L+D+S+TH+TFG+EFT AVE KQ+
Sbjct: 129 AVVAQFDAGELITQREMVSQRVSQELTVRAKQFGFILDDISLTHLTFGREFTLAVEMKQV 188
Query: 188 AQQDAERARFLVEKAEQERKAAVIRAE 214
AQQ+AE+ARF+VEKAEQ++ A++I AE
Sbjct: 189 AQQEAEKARFVVEKAEQQKLASIISAE 215
>CE26775 [O] KOG3083 Prohibitin
Length = 275
Score = 254 bits (648), Expect = 9e-68
Identities = 124/204 (60%), Positives = 164/204 (79%), Gaps = 2/204 (0%)
Query: 13 IPVGLTVSA--IQYSMYDVRGGHRAVIFDRLQGVQQAVIGEGTHFLVPWLQKSILFDVRT 70
+ VGL+++ Q ++Y+V GG RAVIFDR GV+ V+GEGTHFL+PW+QK I+FD+R+
Sbjct: 15 VGVGLSIAGGIAQTALYNVDGGQRAVIFDRFSGVKNEVVGEGTHFLIPWVQKPIIFDIRS 74
Query: 71 KPKNIATNTGTKDLQMVSLTLRVLHRPDVMQLPKIYQNLGIDYDERVLPSIGNEVLKAIV 130
P+ + T TG+KDLQ V++TLR+LHRP +LP IY N+G+DY ERVLPSI NEVLKA+V
Sbjct: 75 TPRAVTTITGSKDLQNVNITLRILHRPSPDRLPNIYLNIGLDYAERVLPSITNEVLKAVV 134
Query: 131 AQFDAAELITQREIVSQRIRAELSKRADEFHIKLEDVSITHMTFGQEFTKAVEQKQIAQQ 190
AQFDA E+ITQRE+VSQR L +RA +F + L+D++ITH+ FG+EFT+AVE KQ+AQQ
Sbjct: 135 AQFDAHEMITQREVVSQRASVALRERAAQFGLLLDDIAITHLNFGREFTEAVEMKQVAQQ 194
Query: 191 DAERARFLVEKAEQERKAAVIRAE 214
+AE+AR+LVEKAEQ + AAV AE
Sbjct: 195 EAEKARYLVEKAEQMKIAAVTTAE 218
>At3g27280 [O] KOG3083 Prohibitin
Length = 279
Score = 251 bits (641), Expect = 6e-67
Identities = 120/207 (57%), Positives = 168/207 (80%)
Query: 8 MARIAIPVGLTVSAIQYSMYDVRGGHRAVIFDRLQGVQQAVIGEGTHFLVPWLQKSILFD 67
+A+ A +G+ +A+ S+Y V GG RAV+FDR +GV +GEGTHFL+P+LQ ++D
Sbjct: 14 LAKAAFGLGVAATALNSSLYTVDGGERAVLFDRFRGVLDQTVGEGTHFLIPYLQTPHIYD 73
Query: 68 VRTKPKNIATNTGTKDLQMVSLTLRVLHRPDVMQLPKIYQNLGIDYDERVLPSIGNEVLK 127
+RTKP ++ +GTKDLQMV+LTLRVL RP+V +LP I+Q LG++YDE+VLPSIGNEVLK
Sbjct: 74 IRTKPHTFSSKSGTKDLQMVNLTLRVLFRPEVSRLPYIFQTLGLEYDEKVLPSIGNEVLK 133
Query: 128 AIVAQFDAAELITQREIVSQRIRAELSKRADEFHIKLEDVSITHMTFGQEFTKAVEQKQI 187
A+VA F+A +L+T+R VS +R L KRA EF+I+L+D++ITH+++G EF++AVE KQ+
Sbjct: 134 AVVANFNADQLLTERPQVSALVRDALIKRAREFNIELDDIAITHLSYGAEFSRAVEAKQV 193
Query: 188 AQQDAERARFLVEKAEQERKAAVIRAE 214
AQQ+AER++F+V KA+QER+AAVIRAE
Sbjct: 194 AQQEAERSKFVVMKADQERRAAVIRAE 220
>At5g40770 [O] KOG3083 Prohibitin
Length = 277
Score = 249 bits (635), Expect = 3e-66
Identities = 121/207 (58%), Positives = 166/207 (79%)
Query: 8 MARIAIPVGLTVSAIQYSMYDVRGGHRAVIFDRLQGVQQAVIGEGTHFLVPWLQKSILFD 67
+A+ A +G + + S++ V GG RAVIFDR +GV +GEGTHFL+P LQ+ +FD
Sbjct: 14 LAKAAFGLGTAATVLNTSLFTVDGGERAVIFDRFRGVMDQTVGEGTHFLIPILQRPHIFD 73
Query: 68 VRTKPKNIATNTGTKDLQMVSLTLRVLHRPDVMQLPKIYQNLGIDYDERVLPSIGNEVLK 127
+RTKP ++ +GTKDLQMV+LTLRVL RP+V +LP I+Q LG++YDE+VLPSIGNEVLK
Sbjct: 74 IRTKPHTFSSISGTKDLQMVNLTLRVLSRPEVSRLPYIFQTLGLEYDEKVLPSIGNEVLK 133
Query: 128 AIVAQFDAAELITQREIVSQRIRAELSKRADEFHIKLEDVSITHMTFGQEFTKAVEQKQI 187
A+VAQF+A +L+T+R VS +R L RA +F+I L+DV+ITH+++G EF++AVEQKQ+
Sbjct: 134 AVVAQFNADQLLTERPHVSALVRESLITRAKDFNIVLDDVAITHLSYGVEFSRAVEQKQV 193
Query: 188 AQQDAERARFLVEKAEQERKAAVIRAE 214
AQQ+AER++F+V KA+QER+AAVIRAE
Sbjct: 194 AQQEAERSKFVVMKADQERRAAVIRAE 220
>YGR231c [O] KOG3090 Prohibitin-like protein
Length = 315
Score = 248 bits (633), Expect = 5e-66
Identities = 120/193 (62%), Positives = 156/193 (80%)
Query: 22 IQYSMYDVRGGHRAVIFDRLQGVQQAVIGEGTHFLVPWLQKSILFDVRTKPKNIATNTGT 81
I ++++V GGHRA+++ R+ GV + EGTHF+ PWL I++DVR KP+N+A+ TGT
Sbjct: 54 INNALFNVDGGHRAIVYSRIHGVSSRIFNEGTHFIFPWLDTPIIYDVRAKPRNVASLTGT 113
Query: 82 KDLQMVSLTLRVLHRPDVMQLPKIYQNLGIDYDERVLPSIGNEVLKAIVAQFDAAELITQ 141
KDLQMV++T RVL RPDV+QLP IY+ LG DYDERVLPSI NEVLKA+VAQF+A++LITQ
Sbjct: 114 KDLQMVNITCRVLSRPDVVQLPTIYRTLGQDYDERVLPSIVNEVLKAVVAQFNASQLITQ 173
Query: 142 REIVSQRIRAELSKRADEFHIKLEDVSITHMTFGQEFTKAVEQKQIAQQDAERARFLVEK 201
RE VS+ IR L +RA +F+I L+DVSIT+MTF EFT AVE KQIAQQDA+RA F+V+K
Sbjct: 174 REKVSRLIRENLVRRASKFNILLDDVSITYMTFSPEFTNAVEAKQIAQQDAQRAAFVVDK 233
Query: 202 AEQERKAAVIRAE 214
A QE++ V+RA+
Sbjct: 234 ARQEKQGMVVRAQ 246
>SPCC1322.16 [O] KOG3090 Prohibitin-like protein
Length = 279
Score = 239 bits (610), Expect = 2e-63
Identities = 116/204 (56%), Positives = 159/204 (77%)
Query: 11 IAIPVGLTVSAIQYSMYDVRGGHRAVIFDRLQGVQQAVIGEGTHFLVPWLQKSILFDVRT 70
+ + +GL A+Q S+++V GGHRA+ + R+ G++ + EGTHFL+PW++ +I +DVR
Sbjct: 21 LLLALGLAGFAVQTSLFNVDGGHRAIKYSRIGGIKNLIYPEGTHFLIPWIETAIDYDVRA 80
Query: 71 KPKNIATNTGTKDLQMVSLTLRVLHRPDVMQLPKIYQNLGIDYDERVLPSIGNEVLKAIV 130
KP+NI++ TGTKDLQMV++ RVL RPDV LPKIY+ LG DYDERVLPSI NEVLK++V
Sbjct: 81 KPRNISSLTGTKDLQMVNINCRVLSRPDVHALPKIYRTLGGDYDERVLPSIVNEVLKSVV 140
Query: 131 AQFDAAELITQREIVSQRIRAELSKRADEFHIKLEDVSITHMTFGQEFTKAVEQKQIAQQ 190
AQF+A++LITQRE VS+ +R L KRA F+I L+DVS+TH+ F EFT AVE KQIAQQ
Sbjct: 141 AQFNASQLITQRERVSRLVRENLMKRAARFNILLDDVSLTHVQFSPEFTAAVEAKQIAQQ 200
Query: 191 DAERARFLVEKAEQERKAAVIRAE 214
DA+RA F V++A E++ ++RA+
Sbjct: 201 DAQRATFYVDRARMEKQGFIVRAQ 224
>At1g03860 [O] KOG3090 Prohibitin-like protein
Length = 286
Score = 235 bits (599), Expect = 4e-62
Identities = 116/207 (56%), Positives = 164/207 (79%)
Query: 8 MARIAIPVGLTVSAIQYSMYDVRGGHRAVIFDRLQGVQQAVIGEGTHFLVPWLQKSILFD 67
+ ++++ GL V A+ S+Y+V GGHRAV+F+RL G+++ V EGTHF+VPW ++ I++D
Sbjct: 18 LLKVSVIGGLGVYALTNSLYNVDGGHRAVMFNRLTGIKEKVYPEGTHFMVPWFERPIIYD 77
Query: 68 VRTKPKNIATNTGTKDLQMVSLTLRVLHRPDVMQLPKIYQNLGIDYDERVLPSIGNEVLK 127
VR +P + + TG+ DLQMV + LRVL RP +LP+IY+ LG +Y ERVLPSI +E LK
Sbjct: 78 VRARPYLVESTTGSHDLQMVKIGLRVLTRPMGDRLPQIYRTLGENYSERVLPSIIHETLK 137
Query: 128 AIVAQFDAAELITQREIVSQRIRAELSKRADEFHIKLEDVSITHMTFGQEFTKAVEQKQI 187
A+VAQ++A++LITQRE VS+ IR L++RA F I L+DVSIT +TFG+EFT A+E KQ+
Sbjct: 138 AVVAQYNASQLITQREAVSREIRKILTERASNFDIALDDVSITTLTFGKEFTAAIEAKQV 197
Query: 188 AQQDAERARFLVEKAEQERKAAVIRAE 214
A Q+AERA+F+VEKAEQ+R++AVIRA+
Sbjct: 198 AAQEAERAKFIVEKAEQDRRSAVIRAQ 224
>At4g28510 [O] KOG3090 Prohibitin-like protein
Length = 288
Score = 233 bits (594), Expect = 2e-61
Identities = 110/207 (53%), Positives = 164/207 (79%)
Query: 8 MARIAIPVGLTVSAIQYSMYDVRGGHRAVIFDRLQGVQQAVIGEGTHFLVPWLQKSILFD 67
+ ++ I GL + +S+Y+V GGHRA++F+RL G++ V EGTH ++PW ++ +++D
Sbjct: 18 LLKVGIIGGLGLYGATHSLYNVEGGHRAIMFNRLVGIKDKVYPEGTHLMIPWFERPVIYD 77
Query: 68 VRTKPKNIATNTGTKDLQMVSLTLRVLHRPDVMQLPKIYQNLGIDYDERVLPSIGNEVLK 127
VR +P + + +G++DLQMV + LRVL RP QLP+IY++LG +Y ERVLPSI NE LK
Sbjct: 78 VRARPYLVESTSGSRDLQMVKIGLRVLTRPMADQLPEIYRSLGENYSERVLPSIINETLK 137
Query: 128 AIVAQFDAAELITQREIVSQRIRAELSKRADEFHIKLEDVSITHMTFGQEFTKAVEQKQI 187
A+VAQ++A++LITQRE VS+ IR L++RA F++ L+DVSIT++TFG+EFT A+E KQ+
Sbjct: 138 AVVAQYNASQLITQREAVSREIRKILTERAANFNVALDDVSITNLTFGKEFTAAIEAKQV 197
Query: 188 AQQDAERARFLVEKAEQERKAAVIRAE 214
A Q+AERA+F+VEKAEQ++++AVIRA+
Sbjct: 198 AAQEAERAKFIVEKAEQDKRSAVIRAQ 224
>At2g20530 [O] KOG3090 Prohibitin-like protein
Length = 286
Score = 231 bits (590), Expect = 5e-61
Identities = 114/208 (54%), Positives = 164/208 (78%), Gaps = 1/208 (0%)
Query: 7 VMARIAIPVGLTVSAIQYSMYDVRGGHRAVIFDRLQGVQQAVIGEGTHFLVPWLQKSILF 66
V+A + I GL++ +++Y+V GGHRA++F+RL G++ V EGTH ++PW ++ I++
Sbjct: 16 VIAAVVIG-GLSLYGATHTLYNVDGGHRAIVFNRLVGIKDKVYPEGTHLMIPWFERPIIY 74
Query: 67 DVRTKPKNIATNTGTKDLQMVSLTLRVLHRPDVMQLPKIYQNLGIDYDERVLPSIGNEVL 126
DVR KP + + +G++DLQMV + LRVL RP QLP++Y++LG +Y ERVLPSI +E L
Sbjct: 75 DVRAKPYLVESTSGSRDLQMVKIGLRVLTRPMADQLPEVYRSLGENYRERVLPSIIHETL 134
Query: 127 KAIVAQFDAAELITQREIVSQRIRAELSKRADEFHIKLEDVSITHMTFGQEFTKAVEQKQ 186
KA+VAQ++A++LITQRE VS+ IR L+ RA FHI L+DVSIT +TFG+EFT A+E KQ
Sbjct: 135 KAVVAQYNASQLITQRESVSREIRKILTLRAANFHIALDDVSITGLTFGKEFTAAIEGKQ 194
Query: 187 IAQQDAERARFLVEKAEQERKAAVIRAE 214
+A Q+AERA+F+VEKAEQ++++AVIRAE
Sbjct: 195 VAAQEAERAKFIVEKAEQDKRSAVIRAE 222
>Hs6005854 [O] KOG3090 Prohibitin-like protein
Length = 299
Score = 229 bits (584), Expect = 2e-60
Identities = 107/206 (51%), Positives = 162/206 (77%), Gaps = 1/206 (0%)
Query: 10 RIAIPVGLTVSAIQYSMYDVRGGHRAVIFDRLQGVQQ-AVIGEGTHFLVPWLQKSILFDV 68
++ + G ++ S++ V GGHRA+ F+R+ GVQQ ++ EG HF +PW Q I++D+
Sbjct: 24 KLLLGAGAVAYGVRESVFTVEGGHRAIFFNRIGGVQQDTILAEGLHFRIPWFQYPIIYDI 83
Query: 69 RTKPKNIATNTGTKDLQMVSLTLRVLHRPDVMQLPKIYQNLGIDYDERVLPSIGNEVLKA 128
R +P+ I++ TG+KDLQMV+++LRVL RP+ +LP +YQ LG+DY+ERVLPSI NEVLK+
Sbjct: 84 RARPRKISSPTGSKDLQMVNISLRVLSRPNAQELPSMYQRLGLDYEERVLPSIVNEVLKS 143
Query: 129 IVAQFDAAELITQREIVSQRIRAELSKRADEFHIKLEDVSITHMTFGQEFTKAVEQKQIA 188
+VA+F+A++LITQR VS IR EL++RA +F + L+DV+IT ++F +E+T AVE KQ+A
Sbjct: 144 VVAKFNASQLITQRAQVSLLIRRELTERAKDFSLILDDVAITELSFSREYTAAVEAKQVA 203
Query: 189 QQDAERARFLVEKAEQERKAAVIRAE 214
QQ+A+RA+FLVEKA+QE++ +++AE
Sbjct: 204 QQEAQRAQFLVEKAKQEQRQKIVQAE 229
>7302549 [O] KOG3090 Prohibitin-like protein
Length = 303
Score = 229 bits (583), Expect = 3e-60
Identities = 104/205 (50%), Positives = 159/205 (76%)
Query: 10 RIAIPVGLTVSAIQYSMYDVRGGHRAVIFDRLQGVQQAVIGEGTHFLVPWLQKSILFDVR 69
++ VG + S+Y V GGHRA+IF RL G+Q + EG H +PW Q I++D+R
Sbjct: 26 KVLAAVGAAAYGVSQSLYTVEGGHRAIIFSRLGGIQSDIYSEGLHVRIPWFQYPIIYDIR 85
Query: 70 TKPKNIATNTGTKDLQMVSLTLRVLHRPDVMQLPKIYQNLGIDYDERVLPSIGNEVLKAI 129
++P+ I++ TG+KDLQM++++LRVL RPD + LP +++ LG+DYDE+VLPSI NEVLK++
Sbjct: 86 SRPRKISSPTGSKDLQMINISLRVLSRPDSLNLPYLHKQLGVDYDEKVLPSICNEVLKSV 145
Query: 130 VAQFDAAELITQREIVSQRIRAELSKRADEFHIKLEDVSITHMTFGQEFTKAVEQKQIAQ 189
+A+F+A++LITQR+ VS IR EL +RA +F+I L+DVS+T ++FG+E+T A+E KQ+AQ
Sbjct: 146 IAKFNASQLITQRQQVSLLIRKELVERARDFNIILDDVSLTELSFGKEYTAAIEAKQVAQ 205
Query: 190 QDAERARFLVEKAEQERKAAVIRAE 214
Q+A+RA F VE+A+QE++ +++AE
Sbjct: 206 QEAQRAVFFVERAKQEKQQKIVQAE 230
>At5g44140 [O] KOG3090 Prohibitin-like protein
Length = 278
Score = 221 bits (564), Expect = 5e-58
Identities = 110/213 (51%), Positives = 163/213 (75%)
Query: 2 SRVADVMARIAIPVGLTVSAIQYSMYDVRGGHRAVIFDRLQGVQQAVIGEGTHFLVPWLQ 61
S + ++ + GL + I SMY+V GGHRA++F+R G++ V EGTHF +P +
Sbjct: 12 SPALSALLKLGVIGGLGLYCIGSSMYNVDGGHRAIVFNRFTGIKDRVYPEGTHFKIPLFE 71
Query: 62 KSILFDVRTKPKNIATNTGTKDLQMVSLTLRVLHRPDVMQLPKIYQNLGIDYDERVLPSI 121
++I++DVR++P + TG+ DLQ V++ LRVL RP +LP+IY+ LG +Y ERVLPSI
Sbjct: 72 RAIIYDVRSRPYVENSQTGSNDLQTVTIGLRVLTRPMGDRLPEIYRTLGQNYGERVLPSI 131
Query: 122 GNEVLKAIVAQFDAAELITQREIVSQRIRAELSKRADEFHIKLEDVSITHMTFGQEFTKA 181
NE LKA+VAQ++A+ LITQRE VS+ IR +++RA +F+I L+DVSIT++ FG+EFT+A
Sbjct: 132 INETLKAVVAQYNASHLITQREAVSREIRKIVTERAAKFNIALDDVSITNLKFGKEFTEA 191
Query: 182 VEQKQIAQQDAERARFLVEKAEQERKAAVIRAE 214
+E+KQ+A Q+AERA+F+VEKAEQ++K+A+IRA+
Sbjct: 192 IEKKQVAAQEAERAKFIVEKAEQDKKSAIIRAQ 224
>At5g14300 [O] KOG3083 Prohibitin
Length = 249
Score = 199 bits (505), Expect = 3e-51
Identities = 103/205 (50%), Positives = 146/205 (70%), Gaps = 26/205 (12%)
Query: 10 RIAIPVGLTVSAIQYSMYDVRGGHRAVIFDRLQGVQQAVIGEGTHFLVPWLQKSILFDVR 69
++A+ +G ++A++ +M+ V GG RAV+F R +G+ + +GEGTH +PW+QK +FD+R
Sbjct: 8 KVALGLGAAIAAVRSTMFTVDGGQRAVMFHRFEGILEEPVGEGTHRKIPWVQKPYIFDIR 67
Query: 70 TKPKNIATNTGTKDLQMVSLTLRVLHRPDVMQLPKIYQNLGIDYDERVLPSIGNEVLKAI 129
TKP I T++GTKDLQMV+LTLRV+ RPDV+ KA+
Sbjct: 68 TKPYKINTDSGTKDLQMVNLTLRVMFRPDVV--------------------------KAV 101
Query: 130 VAQFDAAELITQREIVSQRIRAELSKRADEFHIKLEDVSITHMTFGQEFTKAVEQKQIAQ 189
VAQF+A EL+T+R VS IR L KRA EF+I L+DVSIT +++G+EF+ AVE+KQ+AQ
Sbjct: 102 VAQFNADELLTERPQVSALIRETLIKRAKEFNIVLDDVSITGLSYGKEFSLAVERKQVAQ 161
Query: 190 QDAERARFLVEKAEQERKAAVIRAE 214
Q+AER++F+V KA+QER+AAVIRAE
Sbjct: 162 QEAERSKFVVAKADQERRAAVIRAE 186
>CE02883 [O] KOG3090 Prohibitin-like protein
Length = 286
Score = 198 bits (504), Expect = 4e-51
Identities = 98/213 (46%), Positives = 149/213 (69%)
Query: 2 SRVADVMARIAIPVGLTVSAIQYSMYDVRGGHRAVIFDRLQGVQQAVIGEGTHFLVPWLQ 61
+R A V + G V + SM+ V GHRA++F+R+ G+ + EG HF +PW Q
Sbjct: 8 ARGAGVGLGLVAAAGAAVYGVAQSMFTVEAGHRAIMFNRIGGLSTDLYKEGLHFRIPWFQ 67
Query: 62 KSILFDVRTKPKNIATNTGTKDLQMVSLTLRVLHRPDVMQLPKIYQNLGIDYDERVLPSI 121
I++D+R +P I + TG+KDLQMV++ LRVL RP+ L IY+ LG +++ERVLPSI
Sbjct: 68 YPIIYDIRARPNQIRSPTGSKDLQMVNIGLRVLSRPNPEHLVHIYRTLGQNWEERVLPSI 127
Query: 122 GNEVLKAIVAQFDAAELITQREIVSQRIRAELSKRADEFHIKLEDVSITHMTFGQEFTKA 181
NEVLK +VA+F+A++LITQR+ VS +R L +RA +F+I L+DVS+T + F +++ A
Sbjct: 128 CNEVLKGVVAKFNASQLITQRQQVSMLVRKTLIERALDFNIILDDVSLTELAFSPQYSAA 187
Query: 182 VEQKQIAQQDAERARFLVEKAEQERKAAVIRAE 214
VE KQ+A Q+A+RA F VE+A+Q+++ +++AE
Sbjct: 188 VEAKQVAAQEAQRATFYVERAKQQKQEKIVQAE 220
>Hs17485621 [O] KOG3083 Prohibitin
Length = 250
Score = 187 bits (474), Expect = 1e-47
Identities = 97/207 (46%), Positives = 136/207 (64%), Gaps = 28/207 (13%)
Query: 8 MARIAIPVGLTVSAIQYSMYDVRGGHRAVIFDRLQGVQQAVIGEGTHFLVPWLQKSILFD 67
+ + + + + S + ++Y+V GHRAVIFDR GVQ V+GEGTHF +PW+QK I+FD
Sbjct: 9 IGKFGLALAVVGSMLNSALYNVDAGHRAVIFDRFCGVQDIVVGEGTHFPIPWVQKPIIFD 68
Query: 68 VRTKPKNIATNTGTKDLQMVSLTLRVLHRPDVMQLPKIYQNLGIDYDERVLPSIGNEVLK 127
++P N+ TG+KDLQ V++TL +L P QLP I+ ++ DYDERVLPSI ++LK
Sbjct: 69 CHSRPLNVPVITGSKDLQNVNITLHILSWPVASQLPCIFTSIREDYDERVLPSITTKILK 128
Query: 128 AIVAQFDAAELITQREIVSQRIRAELSKRADEFHIKLEDVSITHMTFGQEFTKAVEQKQI 187
++V+ FDA ELITQRE++S+ QEFT+AVE K++
Sbjct: 129 SVVSHFDAGELITQRELLSR----------------------------QEFTEAVEAKEV 160
Query: 188 AQQDAERARFLVEKAEQERKAAVIRAE 214
QQ+AERARF+VEKAEQ++ AA+I AE
Sbjct: 161 DQQEAERARFVVEKAEQQKIAAIISAE 187
>Hs17468096 [O] KOG3083 Prohibitin
Length = 249
Score = 186 bits (473), Expect = 2e-47
Identities = 97/213 (45%), Positives = 145/213 (67%), Gaps = 23/213 (10%)
Query: 2 SRVADVMARIAIPVGLTVSAIQYSMYDVRGGHRAVIFDRLQGVQQAVIGEGTHFLVPWLQ 61
+++ + + + + + + + ++Y V GHRAV+FDR +GVQ V
Sbjct: 3 AKMFEFIGKFGLALVVAGGVVNSALYSVDAGHRAVVFDRFRGVQDIV------------- 49
Query: 62 KSILFDVRTKPKNIATNTGTKDLQMVSLTLRVLHRPDVMQLPKIYQNLGIDYDERVLPSI 121
P+N+ TG+KDLQ V+LTLR++ RP QLP I+ + G D+DERV PSI
Sbjct: 50 ----------PRNVPVITGSKDLQNVNLTLRIIFRPVASQLPHIFTSSGEDHDERVPPSI 99
Query: 122 GNEVLKAIVAQFDAAELITQREIVSQRIRAELSKRADEFHIKLEDVSITHMTFGQEFTKA 181
N++LK++VA+F+A ELITQRE +S+++ +L++ A F + L+DVS+T++TFG+EF +A
Sbjct: 100 TNKILKSVVARFEAGELITQREQISRQVSDDLTEPAATFGLILDDVSLTYLTFGKEFIEA 159
Query: 182 VEQKQIAQQDAERARFLVEKAEQERKAAVIRAE 214
VE KQIAQQ+AERARF+VEKAEQ++KAA+I AE
Sbjct: 160 VEAKQIAQQEAERARFVVEKAEQQKKAAIISAE 192
>Hs17487396 [O] KOG3083 Prohibitin
Length = 376
Score = 174 bits (442), Expect = 7e-44
Identities = 92/187 (49%), Positives = 125/187 (66%), Gaps = 26/187 (13%)
Query: 28 DVRGGHRAVIFDRLQGVQQAVIGEGTHFLVPWLQKSILFDVRTKPKNIATNTGTKDLQMV 87
+V GHRAVIFD +GVQ V+GE THFL+PW+QK I+FD ++P+N+ TG+KDLQ V
Sbjct: 23 NVDAGHRAVIFDLFRGVQDIVVGERTHFLIPWVQKPIIFDCPSRPRNVPAITGSKDLQNV 82
Query: 88 SLTLRVLHRPDVMQLPKIYQNLGIDYDERVLPSIGNEVLKAIVAQFDAAELITQREIVSQ 147
++TL +L P Q P I+ ++ DYDE+VLPS+ ++LK++VA FDA ELITQRE+
Sbjct: 83 NITLLILFWPVTSQFPCIFTSIREDYDEQVLPSVTTKILKSVVASFDAGELITQREL--- 139
Query: 148 RIRAELSKRADEFHIKLEDVSITHMTFGQEFTKAVEQKQIAQQDAERARFLVEKAEQERK 207
RA F + L+DVS+TH+TFG+EFT+AVE KQ AEQ++K
Sbjct: 140 --------RAATFGLILDDVSLTHLTFGKEFTEAVEAKQ---------------AEQQKK 176
Query: 208 AAVIRAE 214
A+I AE
Sbjct: 177 VAIISAE 183
>Hs22045430 [O] KOG3083 Prohibitin
Length = 236
Score = 164 bits (416), Expect = 7e-41
Identities = 86/213 (40%), Positives = 133/213 (62%), Gaps = 33/213 (15%)
Query: 2 SRVADVMARIAIPVGLTVSAIQYSMYDVRGGHRAVIFDRLQGVQQAVIGEGTHFLVPWLQ 61
++V + + + + + + ++Y+V GHRAVIFDR GVQ V+GEGTH L+PW+Q
Sbjct: 3 AKVFASIGKFGLALAVAGGVVNSALYNVDAGHRAVIFDRFHGVQDIVVGEGTHCLIPWVQ 62
Query: 62 KSILFDVRTKPKNIATNTGTKDLQMVSLTLRVLHRPDVMQLPKIYQNLGIDYDERVLPSI 121
K I+FD R++P+ + G+KDLQ V++TLR+L
Sbjct: 63 KPIIFDCRSRPRKVPVIAGSKDLQNVNITLRIL--------------------------- 95
Query: 122 GNEVLKAIVAQFDAAELITQREIVSQRIRAELSKRADEFHIKLEDVSITHMTFGQEFTKA 181
A+ +QF A+ ++R ++S + +L++RA F + L+DVS+TH+TFG+EFT+A
Sbjct: 96 ----FWAVASQFLASSPASERTMMS--VSNDLTERAATFGLILDDVSLTHLTFGKEFTEA 149
Query: 182 VEQKQIAQQDAERARFLVEKAEQERKAAVIRAE 214
+E KQ+AQQ+ ERARF+VEKAEQ++K A+I AE
Sbjct: 150 MEAKQVAQQEVERARFVVEKAEQQKKVAIISAE 182
>Hs16163999 [O] KOG3083 Prohibitin
Length = 201
Score = 160 bits (404), Expect = 2e-39
Identities = 76/137 (55%), Positives = 113/137 (82%)
Query: 72 PKNIATNTGTKDLQMVSLTLRVLHRPDVMQLPKIYQNLGIDYDERVLPSIGNEVLKAIVA 131
P+N+ TG+KDLQ V++TLR++ +P QLP+I+ ++G DYDE VL I E+LK++VA
Sbjct: 13 PRNVPIITGSKDLQNVNITLRIIFQPVASQLPRIFTSIGEDYDEPVLTYITTEILKSVVA 72
Query: 132 QFDAAELITQREIVSQRIRAELSKRADEFHIKLEDVSITHMTFGQEFTKAVEQKQIAQQD 191
+FDA E+ITQRE+VS+++ +L+++A F + L+DVS+T++TFG+EFT+AVE KQ+AQQ+
Sbjct: 73 RFDAGEVITQRELVSRQVSNDLTEQAATFGLILDDVSLTYLTFGKEFTEAVEAKQVAQQE 132
Query: 192 AERARFLVEKAEQERKA 208
AERARF+ EKAEQ++KA
Sbjct: 133 AERARFVKEKAEQQKKA 149
>Hs17463729 [O] KOG3083 Prohibitin
Length = 396
Score = 156 bits (395), Expect = 2e-38
Identities = 82/153 (53%), Positives = 117/153 (75%), Gaps = 1/153 (0%)
Query: 62 KSILFDVRTKPKNIATNTGTKDLQMVSLTLRVLHRPDVMQLPKIYQNLGIDYDERVLPSI 121
KS++FD R++P + TG+K LQ V++TL +L RP QLP+I+ G DYDERVL SI
Sbjct: 188 KSMIFDCRSRPHTVPVITGSKYLQNVNITLCILFRPVSSQLPRIFAITGEDYDERVLTSI 247
Query: 122 GNEVLKAIVAQFDAAELITQREIVSQRIRAELSKRADEFHIKLEDVSITHMTFGQEFTKA 181
E+LK++VA+FDA ELITQRE+VS+++ +L+++A F + L++VS TH+ F + FT+A
Sbjct: 248 MTEILKSVVARFDAGELITQRELVSRQVSDDLTEQAAIFGLILDNVSWTHLAFKKLFTEA 307
Query: 182 VEQKQIAQQDAERARFLVEKAEQERKAAVIRAE 214
VE KQ+AQQ+AERAR +VEKAEQ++K A+I E
Sbjct: 308 VEAKQVAQQEAERAR-IVEKAEQQKKVAIISTE 339
>Hs18584047 [O] KOG3083 Prohibitin
Length = 185
Score = 137 bits (344), Expect = 2e-32
Identities = 78/172 (45%), Positives = 104/172 (60%), Gaps = 40/172 (23%)
Query: 43 GVQQAVIGEGTHFLVPWLQKSILFDVRTKPKNIATNTGTKDLQMVSLTLRVLHRPDVMQL 102
GVQ V+GE THFL+PW+QK I F + V QL
Sbjct: 15 GVQDIVVGERTHFLIPWIQKPITFVILDH---------------------------VSQL 47
Query: 103 PKIYQNLGIDYDERVLPSIGNEVLKAIVAQFDAAELITQREIVSQRIRAELSKRADEFHI 162
P I+ ++G DE VLPSI ++LK +V +F+AAE ITQRE+VS+++
Sbjct: 48 PCIFTSMGEGCDEPVLPSITTDILKQVVVRFEAAEAITQREVVSRQLM------------ 95
Query: 163 KLEDVSITHMTFGQEFTKAVEQKQIAQQDAERARFLVEKAEQERKAAVIRAE 214
L+D S TH+TFG+EFT+AVE KQ+AQQ+AERARF+VEKA Q++KA +I AE
Sbjct: 96 -LDDTSSTHLTFGKEFTEAVEAKQVAQQEAERARFVVEKAGQQKKATMISAE 146
>Hs22041974 [O] KOG3083 Prohibitin
Length = 193
Score = 106 bits (265), Expect = 2e-23
Identities = 57/118 (48%), Positives = 81/118 (68%), Gaps = 20/118 (16%)
Query: 97 PDVMQLPKIYQNLGIDYDERVLPSIGNEVLKAIVAQFDAAELITQREIVSQRIRAELSKR 156
P QLP+I+ ++G DYDE VLPSI E+LK++V FDA ELITQRE+VS+++ L+++
Sbjct: 19 PVASQLPRIFTSIGEDYDEPVLPSITTEMLKSVVVCFDAGELITQRELVSRQVSDNLTEK 78
Query: 157 ADEFHIKLEDVSITHMTFGQEFTKAVEQKQIAQQDAERARFLVEKAEQERKAAVIRAE 214
+FT+AV KQ+AQQ+AERARF++EKA+Q++KAA+I AE
Sbjct: 79 --------------------DFTEAVGAKQVAQQEAERARFVMEKAKQQKKAAIISAE 116
>Hs17473006 [O] KOG3083 Prohibitin
Length = 130
Score = 68.6 bits (166), Expect = 7e-12
Identities = 36/89 (40%), Positives = 57/89 (63%), Gaps = 8/89 (8%)
Query: 79 TGTKDLQMVSLTLRVLHRPDVMQLPKIYQNLGIDYDERVLPSIGNEVLKAIVAQFDAAEL 138
TG++DLQ V +T ++ +P QLP I+ ++G DYDE ++L +A FD EL
Sbjct: 44 TGSEDLQNVKITECIVFQPVTSQLPHIFTSIGKDYDE--------QILMLPIAYFDTGEL 95
Query: 139 ITQREIVSQRIRAELSKRADEFHIKLEDV 167
ITQRE+VS+ + +L+++A F + L+DV
Sbjct: 96 ITQRELVSKPVNNDLTEQAATFELILDDV 124
Database: KOG eukaryal database 04/03
Posted date: Apr 14, 2003 1:07 PM
Number of letters in database: 30,389,216
Number of sequences in database: 60,738
Lambda K H
0.322 0.135 0.371
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 11,005,768
Number of Sequences: 60738
Number of extensions: 408168
Number of successful extensions: 1363
Number of sequences better than 1.0e-05: 26
Number of HSP's better than 0.0 without gapping: 25
Number of HSP's successfully gapped in prelim test: 1
Number of HSP's that attempted gapping in prelim test: 1325
Number of HSP's gapped (non-prelim): 28
length of query: 226
length of database: 30,389,216
effective HSP length: 103
effective length of query: 123
effective length of database: 24,133,202
effective search space: 2968383846
effective search space used: 2968383846
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.9 bits)