ORF STATUS Function Best COG Functional category Pathways and functional systems
r_klactIV4056 good S KOG3077 Function unknown Uncharacterized conserved protein
Only best alignment is shown:
BLASTP 2.2.3 [May-13-2002]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= r_klactIV4056 1375892 1376644 251
(251 letters)
Database: KOG eukaryal database 04/03
60,738 sequences; 30,389,216 total letters
Searching..................................................done
Color Key for Alignment Scores: 
Score E
Sequences producing significant alignments: (bits) Value
YLR128w [S] KOG3077 Uncharacterized conserved protein 174 1e-43
7294266 [S] KOG3077 Uncharacterized conserved protein 101 1e-21
Hs10190678 [S] KOG3077 Uncharacterized conserved protein 85 1e-16
CE23836 [S] KOG3077 Uncharacterized conserved protein 81 1e-15
SPBC839.03c [S] KOG3077 Uncharacterized conserved protein 80 2e-15
At3g12760 [S] KOG3077 Uncharacterized conserved protein 78 1e-14
7303381 [S] KOG3077 Uncharacterized conserved protein 74 3e-13
CE23837 [S] KOG3077 Uncharacterized conserved protein 67 2e-11
Hs14150015 [S] KOG3077 Uncharacterized conserved protein 60 2e-09
Hs14725791 [S] KOG3077 Uncharacterized conserved protein 57 2e-08
Hs17447631 [S] KOG3077 Uncharacterized conserved protein 54 2e-07
Hs8922603 [S] KOG3077 Uncharacterized conserved protein 52 1e-06
>YLR128w [S] KOG3077 Uncharacterized conserved protein
Length = 269
Score = 174 bits (441), Expect = 1e-43
Identities = 91/253 (35%), Positives = 139/253 (53%), Gaps = 15/253 (5%)
Query: 2 NLTGCTYSVAQEYLRKNGGRVEYALNDYYDN-----VDTIGGMRQS--YNPSLVAIFEKY 54
+LT C V+++YL++N + YALNDYYD D + + Y L +FE Y
Sbjct: 23 SLTKCDPKVSRKYLQRNHWNINYALNDYYDKEIGTFTDEVSTVAHPPVYPKELTQVFEHY 82
Query: 55 SNGVSATEWDSSGLIRFIEDLGISIEDPITLCLSQMLCIDDLTKPVSREQFLNAWSDLCC 114
N +D L++FIE+LG ++ED TLCL+ +L L +P+ RE FL+ W C
Sbjct: 83 INN---NLFDIDSLVKFIEELGYNLEDLATLCLAHLLGYKKLEEPLKREDFLSTWFMQGC 139
Query: 115 DTLRKMKAYLHTLEERLETDKDYFKSIYSYTFPLNTDEGSRHLPKDVAIEYWNIFFKDNK 174
T+ M+ + TL+ +L D YF IY+Y F L D + + D I+YW +FF+ +
Sbjct: 140 STISDMQECIKTLDVKLHEDLQYFTQIYNYAFNLILDPNRKDIDTDEGIQYWKLFFQP-E 198
Query: 175 YALKISKERLNSWLEFINSDDSDPRKQNISNDIWLMFYKFIEQYPNDESLKQNYDEMAAW 234
Y +++ + L +W F+ D K IS D W M F ++YP + + +YDE AAW
Sbjct: 199 YPVRMEPDLLEAWFRFLR----DEGKTTISKDTWRMLLLFFKRYPTIQKIISDYDETAAW 254
Query: 235 PLLIDEYYEFLEE 247
P +IDE+YE L++
Sbjct: 255 PFIIDEFYECLQD 267
>7294266 [S] KOG3077 Uncharacterized conserved protein
Length = 291
Score = 101 bits (251), Expect = 1e-21
Identities = 68/237 (28%), Positives = 113/237 (46%), Gaps = 18/237 (7%)
Query: 15 LRKNGGRVEYALNDYYDNVDTIGGMRQSYNPSLVAIFEKYSNGVSATEWDSSGLIRFIED 74
L++N + E A ++Y+ N + R+ + +F +Y + + S G+I F+ED
Sbjct: 34 LQQNDWKFELASDNYFQNPEYY--YRELDRKRIEQLFMRYRDPSDPLKIGSQGVIHFLED 91
Query: 75 LGISIEDPITLCLSQMLCIDDLTKPVSREQFLNAWSDLCCDTLRKMKAYLHTLEERLETD 134
L + + + L ++ + + SR++F+N DL D++ K+K L LE+ L D
Sbjct: 92 LDLKPDSKLVLIIAWKFHAE-VQCEFSRDEFINGMCDLGIDSIDKLKTKLPILEQELN-D 149
Query: 135 KDYFKSIYSYTFPLNTDEGSRHLPKDVAIEYWNIFFKDNKYALKISKERLNSWLEFINSD 194
FK Y +TF D G + + ++AI YW I L I W +F+
Sbjct: 150 AGKFKDFYHFTFNYAKDPGQKGIDLEMAIAYWCIVLSGRFKFLDI-------WCQFLE-- 200
Query: 195 DSDPRKQNISNDIWLMFYKFIEQYPNDESLKQNYDEMAAWPLLIDEYYEFLEENDKL 251
+ K+ IS D W + F N + NYD AWP+LID++ E+ +END L
Sbjct: 201 --EKHKRAISRDTWNLLLDFAT---NIDDRMSNYDSEGAWPVLIDDFVEWCQENDHL 252
>Hs10190678 [S] KOG3077 Uncharacterized conserved protein
Length = 259
Score = 84.7 bits (208), Expect = 1e-16
Identities = 61/249 (24%), Positives = 119/249 (47%), Gaps = 23/249 (9%)
Query: 1 MNLTGCTYSVAQEYLRKNGGRVEYALNDYYDNVDTIGGMRQSYNPSL-----VAIFEKYS 55
M T + A L +N +++ A ++++ N + +R+S SL ++ +Y
Sbjct: 16 MIFTQSSEKTAVSCLSQNDWKLDVATDNFFQNPELY--IRESVKGSLDRKKLEQLYNRYK 73
Query: 56 NGVSATEWDSSGLIRFIEDLGISIEDPITLCLSQMLCIDDLTKPVSREQFLNAWSDLCCD 115
+ + G+ +F +DL + L ++ + S+++F++ ++L CD
Sbjct: 74 DPQDENKIGIDGIQQFCDDLALDPASISVLIIAWKFRAATQCE-FSKQEFMDGMTELGCD 132
Query: 116 TLRKMKAYLHTLEERLETDKDYFKSIYSYTFPLNTDEGSRHLPKDVAIEYWNIFFKDNKY 175
++ ++KA + +E+ L+ + FK Y +TF + G + L ++AI YWN+
Sbjct: 133 SIEQLKAQIPKMEQELK-EPGRFKDFYQFTFNFAKNPGQKGLDLEMAIAYWNL------- 184
Query: 176 ALKISKERLNSWLEFINSDDSDPRKQNISNDIWLMFYKFIEQYPNDESLKQNYDEMAAWP 235
L + L+ W +F+ + K++I D W + F +D S NYDE AWP
Sbjct: 185 VLNGRFKFLDLWNKFL----LEHHKRSIPKDTWNLLLDFSTMIADDMS---NYDEEGAWP 237
Query: 236 LLIDEYYEF 244
+LID++ EF
Sbjct: 238 VLIDDFVEF 246
>CE23836 [S] KOG3077 Uncharacterized conserved protein
Length = 336
Score = 81.3 bits (199), Expect = 1e-15
Identities = 63/267 (23%), Positives = 115/267 (42%), Gaps = 33/267 (12%)
Query: 4 TGCTYSVAQEYLRKNGGRVEYALNDYYDNVDTIGGMRQSYN---PSLVAIFEKY---SNG 57
T T +V+ +L K +EYA+ Y+DN + G + ++ +F +Y +
Sbjct: 19 TQVTEAVSLNFLAKANWNIEYAMTLYFDNPNLFAGSTPQPSVDRSNIERLFNQYVDPKDK 78
Query: 58 VSATEWDSSGLIRFIEDLGISIEDPITLCLSQMLCIDDLTKPVSREQFLNAWSDLCCDTL 117
V G+ R + DLG D L L+ + S ++++ + L DT+
Sbjct: 79 VGEKRMGPHGINRLLTDLGYEATDRRVLVLAWKFTAQTQCE-FSLDEWVKGMTALQADTV 137
Query: 118 RKMKAYLHTLEERLETDKDYFKSIYSYTFPLNTDEGSRHLPKDVAIEYWNIFFKDNKYAL 177
+ ++ + ++ LE+DK F +Y + F R+L + AI W++ F
Sbjct: 138 QNLRQRIDSINSGLESDKAKFHELYLFAFNYAKSAACRNLDLETAICCWDVLFGQRSTI- 196
Query: 178 KISKERLNSWLEFINSDDSDPRK---QN-------------ISNDIWLMFYKFIEQYPND 221
+ W++F+ + ++ QN IS D W +F+ FI D
Sbjct: 197 ------MTQWIDFLWAQENAAASRLAQNVGASNAKQFKSVWISRDTWNLFWDFILLSKPD 250
Query: 222 ESLKQNYDEMAAWPLLIDEYYEFLEEN 248
S +YD+ AWP+LID++ ++ EN
Sbjct: 251 LS---DYDDEGAWPVLIDQFVDYCREN 274
>SPBC839.03c [S] KOG3077 Uncharacterized conserved protein
Length = 251
Score = 80.5 bits (197), Expect = 2e-15
Identities = 57/209 (27%), Positives = 98/209 (46%), Gaps = 11/209 (5%)
Query: 40 RQSYNPSLVAIFEKYSNGVSATEWDSSGLIRFIEDLGISIEDPITLCLSQMLCIDDLTKP 99
R+ L +F ++S+ + G ++ L IS+EDP TL +S L + +
Sbjct: 47 REEAEKQLNNVFSQFSSKEDKDLIELDGSVQLFTALDISLEDPETLLVSYFLKSPRMGE- 105
Query: 100 VSREQFLNAWSDLCCDTLRKMKAYLHTLEERLETDKDYFKSIYSYTFPLNTDEGSRHLPK 159
RE F+ +L +L ++K + + +D K+IY YT+PL D+G + L
Sbjct: 106 FHRESFVEGALNLSTTSLDQLKLAIKEKVQVWRSDASLQKAIYIYTYPLACDKGKKTLST 165
Query: 160 DVAIEYWNIFFKDNKYALKISKERLNSWLEFINSDDSDPRKQNISNDIWLMFYKFIEQYP 219
+AIE++ I KD + L+ W+ F+ S ++++ D W + F
Sbjct: 166 SIAIEFFQILLKD-------TFPLLDDWIAFLKV--SPIIEKSLPKDTWNELWDFSVFVK 216
Query: 220 NDESLKQNYDEMAAWPLLIDEYYEFLEEN 248
+D + NYD AWP LIDE+ + E+
Sbjct: 217 SDPNC-SNYDFEGAWPTLIDEFVSYYREH 244
>At3g12760 [S] KOG3077 Uncharacterized conserved protein
Length = 250
Score = 78.2 bits (191), Expect = 1e-14
Identities = 62/253 (24%), Positives = 113/253 (44%), Gaps = 30/253 (11%)
Query: 3 LTGCTYSVAQEYLRKNGGRVEYALNDYYD------NVDTIGGMRQSYNPSLVAIFEKYSN 56
+TG + A + L+ + +E A + +Y N + + + YN + YS+
Sbjct: 18 ITGASEKNALQALKASDWHLEAAFDVFYSQPQPRSNAAEVRRLEELYN----RYKDPYSD 73
Query: 57 GVSATEWDSSGLIRFIEDLGISIEDPITLCLSQMLCIDDLTKPVSREQFLNAWSDLCCDT 116
+ A G+ DL + +D +TL LS + + SR++F++ L D+
Sbjct: 74 MILA-----EGISVLCNDLEVEPQDIVTLVLSWHMNAATACE-FSRQEFISGLQALGVDS 127
Query: 117 LRKMKAYLHTLEERLETDKDYFKSIYSYTFPLNTDEGSRHLPKDVAIEYWNIFFKDNKYA 176
+ K++ L + L+ D+ F IY++ F ++G + L D AI W + F + ++
Sbjct: 128 IGKLQEKLPFMRSELK-DEQKFHEIYNFAFGWAKEKGQKSLALDTAIGMWQLLFAEREWP 186
Query: 177 LKISKERLNSWLEFINSDDSDPRKQNISNDIWLMFYKFIEQYPNDESLKQNYDEMAAWPL 236
L + W +F+ D + IS D W +F + + NYD AWP
Sbjct: 187 L------VTHWCDFL----QDRHNKAISKDTWAQLLEFSRMV---DPVLSNYDAEGAWPY 233
Query: 237 LIDEYYEFLEEND 249
LIDE+ E+L + +
Sbjct: 234 LIDEFVEYLYDKN 246
>7303381 [S] KOG3077 Uncharacterized conserved protein
Length = 288
Score = 73.6 bits (179), Expect = 3e-13
Identities = 47/199 (23%), Positives = 89/199 (44%), Gaps = 15/199 (7%)
Query: 46 SLVAIFEKYSNGVSATEWDSSGLIRFIEDLGISIEDPITLCLSQMLCIDDLTKPVSREQF 105
+L +F+ Y + + G+ R DL ++ L L+ L + + ++ +F
Sbjct: 70 TLSKLFDVYKDPDDEEMILTDGIERLCNDLNYQPDEFAILVLAWCLDASQMCR-FTKVEF 128
Query: 106 LNAWSDLCCDTLRKMKAYLHTLEERLETDKDYFKSIYSYTFPLNTDEGSRHLPKDVAIEY 165
+ + DT+ ++ L E L+ D + FK +Y +TF + R L ++AI+
Sbjct: 129 IEGLHKMRADTIDSIRVRLEQTIEMLKADAEMFKQLYRFTFRFGLEPDQRVLSLEMAIDL 188
Query: 166 WNIFFKDNKYALKISKERLNSWLEFINSDDSDPRKQNISNDIWLMFYKFIEQYPNDESLK 225
W + F + + ++W+ F+ + P + I D W M+ F EQ
Sbjct: 189 WKLVFTVQ------TPDLFSNWIHFL---EKHPNIRRIPKDTWNMYLNFTEQCD-----I 234
Query: 226 QNYDEMAAWPLLIDEYYEF 244
QNYD+ AWP L D++ ++
Sbjct: 235 QNYDDTEAWPSLFDDFVDY 253
>CE23837 [S] KOG3077 Uncharacterized conserved protein
Length = 283
Score = 67.4 bits (163), Expect = 2e-11
Identities = 55/244 (22%), Positives = 98/244 (39%), Gaps = 49/244 (20%)
Query: 21 RVEYALNDYYDNVDTIGGMRQSYNPSLVAIFEKYSNGVSATEWDSSGLIRFIEDLGISIE 80
++E N Y D D +G R + G+ R + DLG
Sbjct: 11 KIERLFNQYVDPKDKVGEKRMGPH----------------------GINRLLTDLGYEAT 48
Query: 81 DPITLCLSQMLCIDDLTKPVSREQFLNAWSDLCCDTLRKMKAYLHTLEERLETDKDYFKS 140
D L L+ + S ++++ + L DT++ ++ + ++ LE+DK F
Sbjct: 49 DRRVLVLAWKFTAQTQCE-FSLDEWVKGMTALQADTVQNLRQRIDSINSGLESDKAKFHE 107
Query: 141 IYSYTFPLNTDEGSRHLPKDVAIEYWNIFFKDNKYALKISKERLNSWLEFINSDDSDPRK 200
+Y + F R+L + AI W++ F + W++F+ + ++
Sbjct: 108 LYLFAFNYAKSAACRNLDLETAICCWDVLFGQRSTI-------MTQWIDFLWAQENAAAS 160
Query: 201 ---QN-------------ISNDIWLMFYKFIEQYPNDESLKQNYDEMAAWPLLIDEYYEF 244
QN IS D W +F+ FI D S +YD+ AWP+LID++ ++
Sbjct: 161 RLAQNVGASNAKQFKSVWISRDTWNLFWDFILLSKPDLS---DYDDEGAWPVLIDQFVDY 217
Query: 245 LEEN 248
EN
Sbjct: 218 CREN 221
>Hs14150015 [S] KOG3077 Uncharacterized conserved protein
Length = 237
Score = 60.5 bits (145), Expect = 2e-09
Identities = 53/186 (28%), Positives = 82/186 (43%), Gaps = 32/186 (17%)
Query: 67 GLIRFIEDLGISIEDPITLCLSQMLCIDDLTKPVSREQFLNAWSDLCCDTLRKMKAYLHT 126
G+ +F ED+G+ E+ I L L+ L + + ++E++L + L CD K++
Sbjct: 69 GMEKFCEDIGVEPENIIMLVLAWKLEAESMGF-FTKEEWLKGMTSLQCDCTEKLQNKFDF 127
Query: 127 LEERLETDKDYFKSIYSYTFPLNTDEGSRHLPKDVAIEY--------WNIFFKDNKYALK 178
L +L D FK+IY Y F D+ R L D A W +F +Y L+
Sbjct: 128 LRSQLN-DISSFKNIYRYAFDFARDKDQRSLDIDTAKSMLALLLGRTWPLFSVFYQY-LE 185
Query: 179 ISKERLNSWLEFINSDDSDPRKQNISNDIWLMFYKFIEQYPNDESLKQNYDEMAAWPLLI 238
SK R+ ++ D W +F D S NYDE AWP+L+
Sbjct: 186 QSKYRV------------------MNKDQWYNVLEFSRTVHADLS---NYDEDGAWPVLL 224
Query: 239 DEYYEF 244
DE+ E+
Sbjct: 225 DEFVEW 230
>Hs14725791 [S] KOG3077 Uncharacterized conserved protein
Length = 292
Score = 57.4 bits (137), Expect = 2e-08
Identities = 47/181 (25%), Positives = 80/181 (43%), Gaps = 16/181 (8%)
Query: 67 GLIRFIEDLGISIEDPITLCLSQMLCIDDLTKPVSREQFLNAWSDLCCDTLRKMKAYLHT 126
G+ +F ED+G+ E+ + L L+ L ++ + +++L + L CDT K++ L
Sbjct: 124 GMEKFCEDIGVEPENVVMLVLAWKLDAQNMGY-FTLQEWLKGMTSLQCDTTEKLRNTLDY 182
Query: 127 LEERLETDKDYFKSIYSYTFPLNTDEGSRHLPKDVAIEYWNIFFKDNKYALKISKERLNS 186
L L D FK IY Y F ++ R L + A K L + ++
Sbjct: 183 LRSFLN-DSTNFKLIYRYAFDFAREKDQRSLDINTA-----------KCMLGLLLGKIWP 230
Query: 187 WLEFINSDDSDPRKQNISNDIWLMFYKFIEQYPNDESLKQNYDEMAAWPLLIDEYYEFLE 246
+ + + I+ D W +F D S NYDE AWP+L+DE+ E+ +
Sbjct: 231 LFPVFHQFLEQSKYKVINKDQWCNVLEFSRTINLDLS---NYDEDGAWPVLLDEFVEWYK 287
Query: 247 E 247
+
Sbjct: 288 D 288
>Hs17447631 [S] KOG3077 Uncharacterized conserved protein
Length = 284
Score = 54.3 bits (129), Expect = 2e-07
Identities = 35/109 (32%), Positives = 53/109 (48%), Gaps = 13/109 (11%)
Query: 138 FKSIYSYTFP--LNTDEGSRHLPKDVAIEYWNIFFKDNKYALKISKERLNSWLEFINSDD 195
FK +Y +TF L+++EG L + +AI W + N + L+ WL F+ +
Sbjct: 159 FKDLYQFTFQFGLDSEEGQWSLHRQIAITLWKLVSTQNNSPV------LDQWLNFLT--E 210
Query: 196 SDPRKQNISNDIWLMFYKFIEQYPNDESLKQNYDEMAAWPLLIDEYYEF 244
+ R + IS D W MF F + D S N+ E AWP L D + E+
Sbjct: 211 NPLRIKGISRDSWNMFLNFTQVIGPDLS---NHSEDEAWPNLFDTFVEW 256
>Hs8922603 [S] KOG3077 Uncharacterized conserved protein
Length = 186
Score = 51.6 bits (122), Expect = 1e-06
Identities = 37/146 (25%), Positives = 72/146 (48%), Gaps = 5/146 (3%)
Query: 15 LRKNGGRVEYALNDYYDNVDTIG--GMRQSYNPS-LVAIFEKYSNGVSATEWDSSGLIRF 71
L +N R++ A + ++ N D++ MR + + L ++ +Y + + G+ +F
Sbjct: 30 LTQNEWRLDEATDSFFQNPDSLHRESMRNAVDKKKLERLYGRYKDPQDENKIGVDGIQQF 89
Query: 72 IEDLGISIEDPITLCLSQMLCIDDLTKPVSREQFLNAWSDLCCDTLRKMKAYLHTLEERL 131
+DL + L ++ + SR++FL+ ++L CD++ K+KA L LE+ L
Sbjct: 90 CDDLSLDPASISVLVIAWKFRAATQCE-FSRKEFLDGMTELGCDSMEKLKALLPRLEQEL 148
Query: 132 ETDKDYFKSIYSYTFPLNTDEGSRHL 157
+ D FK Y +TF + G + L
Sbjct: 149 K-DTAKFKDFYQFTFTFAKNPGQKGL 173
Database: KOG eukaryal database 04/03
Posted date: Apr 14, 2003 1:07 PM
Number of letters in database: 30,389,216
Number of sequences in database: 60,738
Lambda K H
0.318 0.137 0.415
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 16,878,910
Number of Sequences: 60738
Number of extensions: 759369
Number of successful extensions: 1907
Number of sequences better than 1.0e-05: 12
Number of HSP's better than 0.0 without gapping: 1
Number of HSP's successfully gapped in prelim test: 11
Number of HSP's that attempted gapping in prelim test: 1892
Number of HSP's gapped (non-prelim): 12
length of query: 251
length of database: 30,389,216
effective HSP length: 104
effective length of query: 147
effective length of database: 24,072,464
effective search space: 3538652208
effective search space used: 3538652208
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)