ORF STATUS Function Best COG Functional category Pathways and functional systems
r_klactIV4251 good U KOG1300 Intracellular trafficking, secretion, and vesicular transport Vesicle trafficking protein Sec1
Only best alignment is shown:
BLASTP 2.2.3 [May-13-2002]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= r_klactIV4251 1445255 1443153 -701
(701 letters)
Database: KOG eukaryal database 04/03
60,738 sequences; 30,389,216 total letters
Searching..................................................done
Color Key for Alignment Scores: 
Score E
Sequences producing significant alignments: (bits) Value
YDR164c [U] KOG1300 Vesicle trafficking protein Sec1 748 0.0
SPCC584.05 [U] KOG1300 Vesicle trafficking protein Sec1 219 1e-56
CE24927 [U] KOG1300 Vesicle trafficking protein Sec1 194 4e-49
Hs5902128 [U] KOG1300 Vesicle trafficking protein Sec1 184 4e-46
Hs4507297 [U] KOG1300 Vesicle trafficking protein Sec1 176 8e-44
7292440 [U] KOG1300 Vesicle trafficking protein Sec1 173 7e-43
Hs6005886 [U] KOG1300 Vesicle trafficking protein Sec1 157 7e-38
At1g12360 [U] KOG1300 Vesicle trafficking protein Sec1 128 3e-29
At4g12120 [U] KOG1300 Vesicle trafficking protein Sec1 123 1e-27
CE17219 [U] KOG1300 Vesicle trafficking protein Sec1 103 7e-22
At1g02010 [U] KOG1300 Vesicle trafficking protein Sec1 89 3e-17
YDR189w [U] KOG1301 Vesicle trafficking protein Sly1 (Sec1 family) 73 1e-12
SPCC74.01 [U] KOG1301 Vesicle trafficking protein Sly1 (Sec1 fam... 66 2e-10
Hs7706407 [U] KOG1301 Vesicle trafficking protein Sly1 (Sec1 fam... 63 2e-09
Hs7706371 [U] KOG1301 Vesicle trafficking protein Sly1 (Sec1 fam... 62 2e-09
>YDR164c [U] KOG1300 Vesicle trafficking protein Sec1
Length = 724
Score = 748 bits (1932), Expect = 0.0
Identities = 379/719 (52%), Positives = 492/719 (67%), Gaps = 18/719 (2%)
Query: 1 MSNLVELQRNFIINILKEVRTEHNIKFXXXXXXXXXXXXSLFADRNDLLTYVTAVDRIDS 60
MS+L+ELQRN++I +L ++ T++N+KF LF +LL VT+VD IDS
Sbjct: 1 MSDLIELQRNYLIGVLNQIETKNNLKFLIIDKTVETILSYLFLTPQELLNNVTSVDLIDS 60
Query: 61 PKRKGQSSVEVIYLLKATKFNINCMDADFGNHSIKYKRAHIRFLSEFPRNLVDHFNKRRY 120
P RKGQSS+E IY+L+ TK+NINC+DADF KY+R HIRFL + F +RY
Sbjct: 61 PTRKGQSSIEAIYILEPTKYNINCIDADFMVRPPKYRRCHIRFLPGLTNPIFQFFQSKRY 120
Query: 121 LTSNVADLKVINCAFTPKEYQYFETLGIDKPLQIFYNPTCKDLVDIGIYKTVQSLLNVCI 180
+ N+ K I F KE Q+FETL ++ LQ+F+N CK L+ + K V SL+++C+
Sbjct: 121 IAQNLESFKPIELGFFVKESQFFETLQMEHSLQVFFNNNCKALIPTNVRKIVGSLVSLCV 180
Query: 181 ITGEYPIVRYS--EPTAEEYALN-----EATLLPKRVAMAFQQELDDYARDHNDFPPENS 233
ITGEYPIVRYS P EE A N A L + +A AFQ +D YAR++ DFPP+N+
Sbjct: 181 ITGEYPIVRYSVSNPVEEEDARNGNAVVNANSLTRSIANAFQIAIDTYARNNPDFPPQNT 240
Query: 234 -RPRAIMVITDRVLDLFSPVLHDFSYQALAYDISKNIDRRTDTYSYKVENETGVMEPKTS 292
RPR+I++ITDR LD F+P+LHDFSYQA+AYD+ N+D + D Y Y ENE G E K S
Sbjct: 241 ERPRSILIITDRTLDPFAPILHDFSYQAMAYDLVANVDTQKDIYHYSAENEAGEQEEKVS 300
Query: 293 RLSDLLDPDWVTMKHFHIVDASEYLTSKVNELIAKNPLLVDRANVKDTSDLLNVVAHLKD 352
+L DL DPDW+ +KH HI+DA+EY+ ++ ELIAKNPLLVDR+NVK+T+DLL+VVAHLKD
Sbjct: 301 KLVDLYDPDWIDLKHQHIMDANEYIQGRIKELIAKNPLLVDRSNVKNTTDLLSVVAHLKD 360
Query: 353 FDEERRRIALHRTLLDECFEHSKTCKLAEHAEIEQILAGYGTDFDGEKCKHISEKLIEHL 412
FDEERRR+ LH+TL+DEC + KLA+ + IEQ L+G+G DF GEK KHI + L+ L
Sbjct: 361 FDEERRRLILHKTLVDECLGENAERKLADISAIEQNLSGFGMDFSGEKIKHIIDDLLPAL 420
Query: 413 SDTSSAVTDRVRYIIEYALYRGGIIDFDFIKLLAFIGVDKSNSWFKHFMQLFKNFNYLGF 472
+ + D++RYII YAL+RGGII+ DFIKLL FIGV + F+ ++++F+N++ + F
Sbjct: 421 AMKEPTILDKLRYIIAYALFRGGIIELDFIKLLNFIGVTHEHENFQQYLKIFRNYDLIDF 480
Query: 473 KLVKDKPKDKPFQKEWTHDTIVNDSTIYQTSRYIPSVGNILGKVITNPLLLKEEQFPYVK 532
KL+KDKPKDKPFQKEW HDT+VND IY TSR++P+VGNIL KVI NPLLL E+ FPY+K
Sbjct: 481 KLIKDKPKDKPFQKEWFHDTLVNDPNIYHTSRFVPAVGNILSKVIANPLLLSEQYFPYLK 540
Query: 533 DKPIELL--EADVADSLNTKSTQPTSLRNPRHKAAWAKTTTQPKGN--RQRFFYYVIGGI 588
DKPIELL E A NT + +SLRNPRHKAAW ++ K N RQRFFYYVIGGI
Sbjct: 541 DKPIELLNEEEFQAGLANTSANSSSSLRNPRHKAAWTTKSSNIKKNIPRQRFFYYVIGGI 600
Query: 589 TYSEIKACYDQSKLNNKDVFVGSDSIWTPLQFMANVEDLTKPRELLRLREDAPVREEPPE 648
+ EIKA YDQS L N+D+F+GSD I TP +F+ VE L PRE + +ED + PP+
Sbjct: 601 SIPEIKAAYDQSNLKNRDIFIGSDEILTPTKFLDEVERLQNPREFFKFKEDQRQQVNPPD 660
Query: 649 FLTASNPPIATAPKHIHTVS------ISQPSRKVERDTTNKEPEVAKKQSKLSRFLKRK 701
FL P+A H+H S S K ++ PE KK+SK SRFLKRK
Sbjct: 661 FLLREMKPVAQPVSHVHLKSQDNSPKSGTSSPKAAGSLKSEPPEKEKKRSKFSRFLKRK 719
>SPCC584.05 [U] KOG1300 Vesicle trafficking protein Sec1
Length = 693
Score = 219 bits (557), Expect = 1e-56
Identities = 173/691 (25%), Positives = 324/691 (46%), Gaps = 44/691 (6%)
Query: 4 LVELQRNFIINILKEVRTEHNIKFXXXXXXXXXXXXSLFADRNDLLTYVTAVDRIDSPKR 63
L+ELQ+ ++ + V K + L + AV+ +++P R
Sbjct: 3 LLELQKELFLSKINSVECATKWKVLIVDTKTADIINHFITIHSLLEEKIAAVEILENP-R 61
Query: 64 KGQSSVEVIYLLKATKFNINCMDADFGNHSIKYKRAHIRFLSEFPRNLVDHFNKRRYLTS 123
SS E +Y+L + + ++C+ D + +Y HI FL L++ R + S
Sbjct: 62 TPNSSFEALYILHSEEKLVDCILKD-EEYDKRYPGIHIVFLDMVKEPLINKLRTSR-IAS 119
Query: 124 NVADLKVINCAFTPKEYQYFETLGIDKPLQIFYNPTCKDLVDIGIYKTVQSLLNVCIITG 183
+ ++V FT E +YF+ L++ Y+P+ ++ + K + +VC+ G
Sbjct: 120 KIRTVQVAYLDFTSLESRYFQVHDSFSGLRL-YHPSNAAIIRQELSKVAHGIFSVCVSLG 178
Query: 184 EYPIVRYSEPTAEEYALNEATLLPKRVAMAFQQELDDYARDHNDFPPENSRPRAIMVITD 243
P +R P +A + + +A + +++Y H + S+ ++V D
Sbjct: 179 ISPNIRCYYPKNAPHASKTMSFI---LANQLSEIVEEYCSKHPGYHEAASKSTCLIV--D 233
Query: 244 RVLDLFSPVLHDFSYQALAYDISKNIDRRTDTYSYKVENETGVMEPKTSRLSDLLDPDWV 303
R LD +P LH+F+YQA+ +D+ + + + Y Y++ G E +T +L D D +
Sbjct: 234 RSLDTAAPFLHEFTYQAMIHDL---LPIKNEQYPYEILGPQGT-EKRTGKLDDD-DLVYT 288
Query: 304 TMKHFHIVDASEYLTSKVNELIAKNPLLVDRANVKDTSDLLNVVAHLKDFDEERRRIALH 363
T++H H+ DA E L N+ N L +D+ +D+ +++A L DF E R + +LH
Sbjct: 289 TIRHMHMRDAIEKLMKDFNQFCIDNTLFLDKERATSLNDMRSMLAGLSDFQELRDQYSLH 348
Query: 364 RTLLDECFEHSKTCKLAEHAEIEQILAGYGTDFDGEKCKHISEKLIEHLSDTSSAVTDRV 423
T+ EC + +L IEQ L+ G++ +G+ + + +L+ L + ++ + ++
Sbjct: 349 LTMAQECMNIFEKQQLNLIGAIEQDLST-GSNVEGKVPRSVLSELLPLLDEGNAEESTKI 407
Query: 424 RYIIEYALYRGGIIDFDFIKLLAFIGVDKSNSWFKHFMQLFKNFNYLGFKLVKDKPKDKP 483
R ++ Y +YR GII D +L + S Q+F+N LG +++K+
Sbjct: 408 RLLLLYIIYRDGIILQDLFRLFRHSNLSTSRE------QIFQNLEQLGTRVIKNLTDQSS 461
Query: 484 FQKEWTHDTIVNDSTIYQTSRYIPSVGNILGKVITNPLLLKEEQFPYVKDKPIELLEADV 543
+KE + + +Y+ SRY+P++ +L +I + L E FPYV++ +
Sbjct: 462 KRKEVANSLPAGED-VYELSRYVPTLKVVLENLIQDKL--DPELFPYVRNTTPQ------ 512
Query: 544 ADSLNTKSTQPTSLRNPRHKAAWAKTTTQP-KGNRQRFFYYVIGGITYSEIKACYDQSKL 602
S + TSLR+ R +W ++ + K R++ +V GG T+SE++ CY+ S
Sbjct: 513 ----TEVSMEQTSLRSSR--PSWTRSRSMASKLPREKMLVFVAGGTTFSELRTCYELSDK 566
Query: 603 NNKDVFVGSDSIWTPLQFMANVEDLTKPRELLRLREDAPVREEPPEFLTASNPPIATAPK 662
NKD+++GS ++P +++ +PRE L+ ED P R P S I P
Sbjct: 567 YNKDIYIGSTVCYSPNEWLDFFSKFQQPREALKFPEDKP-RHIPCLEARPSPNRIQEQP- 624
Query: 663 HIHTVSISQPSRKVERDTTNKEPEVAKKQSK 693
+I PS + E +++ + K + K
Sbjct: 625 -----NIDVPSTRYENTSSSDAVSIHKDEKK 650
>CE24927 [U] KOG1300 Vesicle trafficking protein Sec1
Length = 591
Score = 194 bits (493), Expect = 4e-49
Identities = 163/597 (27%), Positives = 269/597 (44%), Gaps = 75/597 (12%)
Query: 52 VTAVDRIDSPKRKGQSSVEVIYLLKATKFNINCMDADFGNHSIKYKRAHIRFLSEFPRNL 111
+T V+ ++ +R+ ++E IYL+ T +I+ + D+ ++ YK AH+ F L
Sbjct: 55 ITIVEDLNK-RREPLPTLEAIYLIAPTAESIDKLIQDYCARNL-YKCAHVFFTEACSDQL 112
Query: 112 VDHFNKRRYLTSNVADLKVINCAFTPKEYQYFETLGIDKP--LQIFYNPTCKDLVDIGIY 169
+K + LK IN AFTP E Q F +D P ++YN + + +
Sbjct: 113 FSTLSKSA-AARFIKTLKEINIAFTPYESQVFN---LDSPDTFFLYYNAQKQGGLTSNLE 168
Query: 170 KTVQSLLNVCIITGEYPIVRYSEPTAEEYALNEATLLPKRVAMAFQQELDDYARDHNDFP 229
+ + + VC GEYP +RY L +Q+LD Y D
Sbjct: 169 RIAEQIATVCATLGEYPSLRYRADFERNVELGHLV----------EQKLDAYKADDPSMG 218
Query: 230 PENSRPRAIMVITDRVLDLFSPVLHDFSYQALAYDISKNIDRRTDTYSYKVENETGVMEP 289
+ R+ ++I DR D +P+LH+ + QA+ YD+ + D Y Y+ +E
Sbjct: 219 EGADKARSQLIIIDRGYDAITPLLHELTLQAMCYDL---LGIENDVYKYETGGSDENLEK 275
Query: 290 KTSRLSDLLDPDWVTMKHFHIVDASEYLTSKVNELIAK--NPLLVDRANVKDTSDLLNVV 347
+ L D D WV M+H HI S+ +T + + N +D ++KD S L +
Sbjct: 276 EV--LLDENDDLWVEMRHKHIAVVSQEVTKNLKKFSESKGNKGTMDSKSIKDLSML---I 330
Query: 348 AHLKDFDEERRRIALHRTLLDECFEH-----SKTCKLAEHAEIEQILAGYGTDFDGEKCK 402
+ +E + + H +L +EC + K CK +EQ L+ G D +GE+ +
Sbjct: 331 KRMPQHKKELNKFSTHISLAEECMKQYQQGVDKLCK------VEQDLS-TGIDAEGERVR 383
Query: 403 HISEKLIEHLSDTSSAVTDRVRYIIEYALYRGGIIDFDFIKLLAFIGVDKSNSWFKHFMQ 462
+ ++ L D + DR+R I+ Y L + GI D + KLL + ++ +
Sbjct: 384 DAMKLMVPLLIDPAVRCEDRLRLILLYILSKNGITDENLNKLLQHANISMADK------E 437
Query: 463 LFKNFNYLGFKLVKDKPKDK---PFQKEWTHDTIVNDSTIYQTSRYIPSVGNILGKVITN 519
N YLG +V D + K P +KE H+ +YQ+SR++P + +I+ I
Sbjct: 438 TITNAAYLGLNIVTDTGRKKTWTPTKKERPHE------QVYQSSRWVPVIKDIIEDAIDE 491
Query: 520 PLLLKEEQFPYVKDKPIELLEADVADSLNTKSTQPTSLRNPRHKAAWAKTTTQPKGNRQ- 578
L K FP++ + + N P S R W K Q R
Sbjct: 492 RLDTK--HFPFLAGRQV-----------NQGYRAPASAR----YGQWHKERGQQSNYRSG 534
Query: 579 -RFFYYVIGGITYSEIKACYDQSKLNNK-DVFVGSDSIWTPLQFMANVEDLTKPREL 633
R Y+IGG+T+SE++ACY+ + +V +GSD I TP +F+ N+ DL KPR++
Sbjct: 535 PRLIIYIIGGVTFSEMRACYEVTAARKPWEVVIGSDRIITPDKFLTNLRDLNKPRDI 591
>Hs5902128 [U] KOG1300 Vesicle trafficking protein Sec1
Length = 593
Score = 184 bits (467), Expect = 4e-46
Identities = 160/596 (26%), Positives = 266/596 (43%), Gaps = 69/596 (11%)
Query: 52 VTAVDRIDSPKRKGQSSVEVIYLLKATKFNINCMDADF-GNHSIKYKRAHIRFLSEFPRN 110
+T V+ I+ +R+ S+E IYLL T+ ++ + DF G + YK AHI F P
Sbjct: 55 ITIVEDINK-RREPIPSLEAIYLLSPTEKSVQALIKDFQGTPTFTYKAAHIFFTDTCPEP 113
Query: 111 LVDHFNKRRYLTSNVADLKVINCAFTPKEYQYFETLGIDKPLQIF--YNPTCKDLVDIGI 168
L + R L V LK I+ AF P E Q F +D P + Y P + +
Sbjct: 114 LFSELGRSR-LAKVVKTLKEIHLAFLPYEAQVFS---LDAPHSTYNLYCPFRAEERTRQL 169
Query: 169 YKTVQSLLNVCIITGEYPIVRYSEPTAEEYALNEATLLPKRVAMAFQQELDDYARDHNDF 228
Q + +C EYP +RY + + L A L +L+ + D
Sbjct: 170 EVLAQQIATLCATLQEYPAIRYRKGPEDTAQLAHAVLA----------KLNAFKADTPSL 219
Query: 229 PPENSRPRAIMVITDRVLDLFSPVLHDFSYQALAYDISKNIDRRTDTYSYKVENETGVME 288
+ R+ ++I DR D SP+LH+ ++QA+AYD+ +D DTY Y+ TG+ E
Sbjct: 220 GEGPEKTRSQLLIMDRAADPVSPLLHELTFQAMAYDL---LDIEQDTYRYET---TGLSE 273
Query: 289 PKTSRLSDLLDPD---WVTMKHFHIVDASEYLTSKVNELIAKNPLLVDRANVKDTSDLLN 345
+ + LLD D WV ++H HI D S+ +T + L D+AN+KD S +L
Sbjct: 274 AREKAV--LLDEDDDLWVELRHMHIADVSKKVTELLRTFCESKRLTTDKANIKDLSQILK 331
Query: 346 VVAHLKDFDEERRRIALHRTLLDECFEHSKTCKLAEHAEIEQILAGYGTDFDGEKCKHIS 405
+ + +E + + H L D+C +H K + + +EQ LA G+D +GEK K
Sbjct: 332 ---KMPQYQKELNKYSTHLHLADDCMKHFKG-SVEKLCSVEQDLA-MGSDAEGEKIKDSM 386
Query: 406 EKLIEHLSDTSSAVTDRVRYIIEYALYRGGIIDFDFIKLLAFIGVDKSNSWFKHFMQLFK 465
+ ++ L D + D++R ++ Y L R G+ + + KL+ V +S ++ QL
Sbjct: 387 KLIVPVLLDAAVPAYDKIRVLLLYILLRNGVSEENLAKLIQHANVQAHSSLIRNLEQLGG 446
Query: 466 NFNYLGFKLVKDK--PKDKPFQKEWTHDTIVNDSTIYQTSRYIPSVGNILGKVITNPLLL 523
G + P+++ YQ SR+ P + +++ + + L
Sbjct: 447 TVTNPGGSGTSSRLEPRERM-------------EPTYQLSRWTPVIKDVMEDAVED--RL 491
Query: 524 KEEQFPYVKDKPIELLEADVADSLNTKSTQPTSLRNPRHKAAWAKTTTQPKGNR-QRFFY 582
+P+ V+D T S+Q H W K + R
Sbjct: 492 DRNLWPF------------VSDPAPTASSQAAVSARFGH---WHKNKAGVEARAGPRLIV 536
Query: 583 YVIGGITYSEIKACYDQSKLNNK--DVFVGSDSIWTPLQFMANVEDLTKPRELLRL 636
YV+GG+ SE++A Y+ ++ +V +GS I TP +F+ +++ L K E + L
Sbjct: 537 YVMGGVAMSEMRAAYEVTRATEGKWEVLIGSSHILTPTRFLDDLKALDKKLEDIAL 592
>Hs4507297 [U] KOG1300 Vesicle trafficking protein Sec1
Length = 603
Score = 176 bits (447), Expect = 8e-44
Identities = 162/618 (26%), Positives = 289/618 (46%), Gaps = 83/618 (13%)
Query: 47 DLLTY-VTAVDRIDSPKRKGQSSVEVIYLLKATKFNINCMDADFGNH-SIKYKRAHIRFL 104
D++T +T V+ I+ +R+ S+E +YL+ ++ +++ + +DF + + KY+ AH+ F
Sbjct: 49 DIMTEGITIVEDINK-RREPLPSLEAVYLITPSEKSVHSLISDFKDPPTAKYRAAHVFFT 107
Query: 105 SEFPRNLVDHFNKRRYLTSNVADLKVINCAFTPKEYQYFETLGIDKPLQIFYNPTCKDLV 164
P L + K R + L IN AF P E Q + D Q FY+P +
Sbjct: 108 DSCPDALFNELVKSR-AAKVIKTLTEINIAFLPYESQVYSLDSADS-FQSFYSPHKAQMK 165
Query: 165 DIGIYKTVQSLLNVCIITGEYPIVRYSEPTAEEYALNEATLLPKRVAMAFQQELDDYARD 224
+ + + + + +C EYP VRY EY N +A Q +LD Y D
Sbjct: 166 NPILERLAEQIATLCATLKEYPAVRYRG----EYKDNAL------LAQLIQDKLDAYKAD 215
Query: 225 HNDFPPENSRPRAIMVITDRVLDLFSPVLHDFSYQALAYDISKNIDRRTDTYSYKVENET 284
+ R+ ++I DR D SPVLH+ ++QA++YD+ + D Y Y+ +
Sbjct: 216 DPTMGEGPDKARSQLLILDRGFDPSSPVLHELTFQAMSYDL---LPIENDVYKYET---S 269
Query: 285 GVMEPKTSRLSDLLDPD---WVTMKHFHIVDASEYLTSKVNELIAKNPLLV-DRANVKDT 340
G+ E + + LLD D W+ ++H HI + S+ +T + + + + ++ ++D
Sbjct: 270 GIGEARVKEV--LLDEDDDLWIALRHKHIAEVSQEVTRSLKDFSSSKRMNTGEKTTMRDL 327
Query: 341 SDLLNVVAHLKDFDEERRRIALHRTLLDECFEH-----SKTCKLAEHAEIEQILAGYGTD 395
S +L + + +E + + H L ++C +H K C+ +EQ LA GTD
Sbjct: 328 SQMLK---KMPQYQKELSKYSTHLHLAEDCMKHYQGTVDKLCR------VEQDLA-MGTD 377
Query: 396 FDGEKCKHISEKLIEHLSDTSSAVTDRVRYIIEYALYRGGIIDFDFIKLLAFIGVDKSNS 455
+GEK K ++ L D + + D++R I+ Y + GI + + KL+ + +S
Sbjct: 378 AEGEKIKDPMRAIVPILLDANVSTYDKIRIILLYIFLKNGITEENLNKLIQHAQIPPEDS 437
Query: 456 WFKHFMQLFKNFNYLGFKLVKD---KPKDKPFQKEWTHDTIVNDSTIYQTSRYIPSVGNI 512
++ N +LG +V D + + KP +KE +++ T YQ SR+ P + +I
Sbjct: 438 ------EIITNMAHLGVPIVTDSTLRRRSKPERKE-----RISEQT-YQLSRWTPIIKDI 485
Query: 513 LGKVITNPLLLKEEQFPYVKDKPIELLEADVADSLNTKSTQPTSLRNPRHKAAWAKTTTQ 572
+ I + L K +PY+ + S + ST S R W K
Sbjct: 486 MEDTIEDKLDTK--HYPYISTR-----------SSASFSTTAVSAR----YGHWHKNKAP 528
Query: 573 PK-GNRQRFFYYVIGGITYSEIKACYDQSKLNNK-DVFVGSDSIWTPLQFMANVEDLTKP 630
+ + R +++GG++ +E++ Y+ ++ N K +V +GS I TP +F+ DL P
Sbjct: 529 GEYRSGPRLIIFILGGVSLNEMRCAYEVTQANGKWEVLIGSTHILTPTKFLM---DLRHP 585
Query: 631 --RELLRL--REDAPVRE 644
RE R+ + AP E
Sbjct: 586 DFRESSRVSFEDQAPTME 603
>7292440 [U] KOG1300 Vesicle trafficking protein Sec1
Length = 597
Score = 173 bits (439), Expect = 7e-43
Identities = 155/587 (26%), Positives = 266/587 (44%), Gaps = 66/587 (11%)
Query: 52 VTAVDRIDSPKRKGQSSVEVIYLLKATKFNINCMDADFGNHSIK-YKRAHIRFLSEFPRN 110
+T V+ I+ KR+ +++ IYL+ + ++ + DF N + Y+ AH+ F P
Sbjct: 66 ITLVEDINK-KREPLPTMDAIYLITPSDESVRGLIRDFENPARPMYRYAHVFFTEVCPEE 124
Query: 111 LVDHFNKRRYLTSNVADLKVINCAFTPKEYQYFETLGIDKP--LQIFYNPTCKDLVDIGI 168
L + K + LK IN AF P E Q F +D P Q Y+P + I
Sbjct: 125 LFNDLCKS-CAAGKIKTLKEINIAFLPYECQVFS---LDSPDTFQCLYSPAFASIRSKHI 180
Query: 169 YKTVQSLLNVCIITGEYPIVRYSEPTAEEYALNEATLLPKRVAMAFQQELDDYARDHNDF 228
+ + + +C GEYP VRY L A + QQ+LD Y D
Sbjct: 181 ERIAEQIATLCATLGEYPNVRYRSDWDRNIDL----------AASVQQKLDAYKADDATM 230
Query: 229 PPENSRPRAIMVITDRVLDLFSPVLHDFSYQALAYDISKNIDRRTDTYSYKVENETGVME 288
+ R+ ++I DR D SP+LH+ + QA+AYD+ ++ D Y Y G +
Sbjct: 231 GEGPEKARSQLLILDRGFDCVSPLLHELTLQAMAYDLLPIVN---DVYRY----TPGPNQ 283
Query: 289 PKTSRLSDLLDPDWVTMKHFHIVDASEYLTSKVNELI-AKNPLLVDRANVKDTSDLLNVV 347
P L D D WV ++H HI S +T + + +K D+++++D S + +
Sbjct: 284 PDKEVLLDENDDLWVELRHEHIAVVSTQVTQNLKKFTDSKRMGSADKSSMRDLSQM---I 340
Query: 348 AHLKDFDEERRRIALHRTLLDECFEHSKTCKLAEHAEIEQILAGYGTDFDGEKCKHISEK 407
+ + +E + + H L ++C + S + + +EQ LA GTD +GEK K
Sbjct: 341 KKMPQYQKELSKYSTHLHLAEDCMK-SYQNYVDKLCRVEQDLA-MGTDAEGEKIKDHMRN 398
Query: 408 LIEHLSDTSSAVTDRVRYIIEYALYRGGIIDFDFIKLLAFIGVDKSNSWFKHFMQLFKNF 467
++ L D + + D+VR I Y + + GI + + KL + + + +N
Sbjct: 399 IVPILLDANVSNYDKVRIIALYVMIKNGISEENLTKLFTHAQLSPKD------QDMVRNL 452
Query: 468 NYLGFKLVKDKPKDK---PFQKEWTHDTIVNDSTIYQTSRYIPSVGNILGKVITNPLLLK 524
+ LG ++ D K + P ++ T T YQ SR+ P + +I+ I + L L+
Sbjct: 453 SCLGINVIADSRKKQYSVPRKERTTEST-------YQMSRWTPVIKDIMEDCIEDKLDLR 505
Query: 525 EEQFPYVKDKPIELLEADVADSLNTKSTQPTSLRNPRHKAAWAKTTTQPK-GNRQRFFYY 583
FP+++ + + NT PTS R W K Q + N R +
Sbjct: 506 --HFPFLEGR-----------AQNTNYHAPTSAR----YGHWHKDKGQAQVKNVPRLIVF 548
Query: 584 VIGGITYSEIKACYD-QSKLNNKDVFVGSDSIWTPLQFMANVEDLTK 629
++GG++ SE++ Y+ + + N +V VGS I +P F++++ L+K
Sbjct: 549 IVGGVSMSEMRCAYEVTNAVRNWEVLVGSSHILSPEIFLSDLGSLSK 595
>Hs6005886 [U] KOG1300 Vesicle trafficking protein Sec1
Length = 592
Score = 157 bits (396), Expect = 7e-38
Identities = 143/595 (24%), Positives = 271/595 (45%), Gaps = 69/595 (11%)
Query: 52 VTAVDRIDSPKRKGQSSVEVIYLLKATKFNINCMDADFGNHSI-KYKRAHIRFLSEFPRN 110
+T V+ I R+ ++ +Y + T +++C DF + S KYK A+I F P N
Sbjct: 59 ITVVENIYK-NREPVRQMKALYFITPTSKSVDCFLHDFASKSENKYKAAYIYFTDFCPDN 117
Query: 111 LVDHFNK-RRYLTSNVADLKVINCAFTPKEYQYFETLGIDKPLQIFYNPTCKDLV--DIG 167
L FNK + + ++ K IN +F P E Q + TL + Y+P + D
Sbjct: 118 L---FNKIKASCSKSIRRCKEINISFIPHESQVY-TLDVPDAFYYCYSPDPGNAKGKDAI 173
Query: 168 IYKTVQSLLNVCIITGEYPIVRYSEPTAEEYALNEATLLPKRVAMAFQQELDDYARDHND 227
+ ++ VC E P VRY + + ++A +++L+DY + ++
Sbjct: 174 METMADQIVTVCATLDENPGVRYKSKPLDNAS---------KLAQLVEKKLEDYYKI-DE 223
Query: 228 FPPENSRPRAIMVITDRVLDLFSPVLHDFSYQALAYDISKNIDRRTDTYSYKVE--NETG 285
+ + ++I DR D S VLH+ ++QA+AYD+ + DTY YK + +
Sbjct: 224 KSLIKGKTHSQLLIIDRGFDPVSTVLHELTFQAMAYDL---LPIENDTYKYKTDGKGKEA 280
Query: 286 VMEPKTSRLSDLLDPDWVTMKHFHIVDASEYLTSKVNELIAKNPLLVDRANVKDTSDLLN 345
++E + D WV ++H HI E + + E+ + + ++ + L+
Sbjct: 281 ILEEE--------DDLWVRIRHRHIAVVLEEIPKLMKEISSTKKATEGKTSLSALTQLMK 332
Query: 346 VVAHLKDFDEERRRIALHRTLLDECFEHSKTCKLAEHAEIEQILAGYGTDFDGEKCKHIS 405
+ H F ++ + +H L ++C K + + + EQ LA GTD +G+K K
Sbjct: 333 KMPH---FRKQITKQVVHLNLAEDCMNKFK-LNIEKLCKTEQDLA-LGTDAEGQKVKDSM 387
Query: 406 EKLIEHLSDTSSAVTDRVRYIIEYALYRGGIIDFDFIKLLAFIGVDKSNSWFKHFMQLFK 465
L+ L + + D++R I+ Y G + + +L+ + + + + +
Sbjct: 388 RVLLPVLLNKNHDNCDKIRAILLYIFSINGTTEENLDRLIQNVKIGNES-------DMIR 440
Query: 466 NFNYLGFKLVKDKPKDKPFQKEWTHDTIVNDSTIYQTSRYIPSVGNILGKVITNPLLLKE 525
N++YLG +V + KP +K+ + + +Q SR+ P + +I+ I N L KE
Sbjct: 441 NWSYLGVPIVPQSQQGKPLRKDRSAE------ETFQLSRWTPFIKDIMEDAIDNRLDSKE 494
Query: 526 EQFPYVKDKPIELLEADVADSLNTKSTQPTSLRNPRHKAAWAKTTTQPKGNRQRFFYYVI 585
+PY P ++ S ++ + PR + + N + +VI
Sbjct: 495 --WPYCSQCP----------AVWNGSGAVSARQKPR------ANYLEDRKNGSKLIVFVI 536
Query: 586 GGITYSEIKACYDQSKLNNK-DVFVGSDSIWTPLQFMANVEDLTKPRELLRLRED 639
GGITYSE++ Y+ S+ + +V +GS + TP + + +++ L KP++ + L +D
Sbjct: 537 GGITYSEVRGAYEVSQAHKSCEVIIGSTHVLTPKKLLDDIKMLNKPKDKVSLIKD 591
>At1g12360 [U] KOG1300 Vesicle trafficking protein Sec1
Length = 637
Score = 128 bits (321), Expect = 3e-29
Identities = 140/605 (23%), Positives = 251/605 (41%), Gaps = 57/605 (9%)
Query: 62 KRKGQSSVEVIYLLKATKFNINCMDADFGNHSIKYKRAHIRFLSEFPRNLVDHFNKRRYL 121
+R+ S++ IY ++ TK N+ +D S YK+A + F S + LV H K +
Sbjct: 50 RRQPLPSMDAIYFIQPTKENVIMFLSDMSGKSPLYKKAFVFFSSPVSKELVGHIKKDSSV 109
Query: 122 TSNVADLKVINCAFTPKEYQYFETLGIDKPLQIFYNPTCKDLVDIGIYKTVQSLLNVCII 181
+ L+ +N F + Q F T +F + D + + V
Sbjct: 110 LPRIGALREMNLEFFAIDSQGFITDHERALEDLFGDEETSRKGDACLNVMASRIATVFAS 169
Query: 182 TGEYPIVRYSEPTAEEYALNEA--TLLPKRVAMAFQQELDDYARDHNDFPPENSRPRAIM 239
E+P VRY + + + L+P ++A L + + +FP + +
Sbjct: 170 LREFPAVRYRAAKSLDASTMTTLRDLIPTKLAAGIWNCLAKHKQSIENFPQTET---CEL 226
Query: 240 VITDRVLDLFSPVLHDFSYQALAYDISKNIDRRTDTYSYKVENETGVMEPKTSRLSDLLD 299
+I DR +D +PV+H+++Y A+ +D+ ++ + Y + + +++G K L + D
Sbjct: 227 LILDRSIDQIAPVIHEWTYDAMCHDL---LNMEGNKYVHVIPSKSGGQPEKKDVLLEEHD 283
Query: 300 PDWVTMKHFHIVDASEYLTSKVNELIAKNPLLV-----DRANVKDTSDLLNVVAHLKDFD 354
P W+ ++H HI DASE L K+ ++KN D A + T DL +V L +
Sbjct: 284 PIWLELRHAHIADASERLHDKMTNFLSKNKAAQLQGKRDGAEL-STRDLQKMVQALPQYS 342
Query: 355 EERRRIALHRTLLDECFEHSKTCKLAEHAEIEQILAGYGTDFDGEKCKHISEKLIEHLSD 414
E+ +++LH + + + + L E ++EQ L F K + I++LS
Sbjct: 343 EQIDKLSLHVEIARKLNDLIREQGLRELGQLEQDLV-----FGDAGMKDV----IKYLST 393
Query: 415 TSSAVTD-RVRYIIEYA-LYRGGIIDFDFIKLLAFIGVDKSNSWFKHFMQLF------KN 466
A + ++R ++ A +Y L+ + + + M L K
Sbjct: 394 QEEASREGKLRLLMILATIYPEKFEGEKGQNLMKLAKLSSDDMTAVNNMSLLGSAVDAKK 453
Query: 467 FNYLGFKLVKDKPKDK-PFQKEWTHDTIVNDSTIYQTSRYIPSVGNILGKVITNPLLLKE 525
GF L D K K +KE + +Q SR+ P + ++ K+ L +
Sbjct: 454 NTPGGFTLKFDLHKKKRAVRKE------RQEEAAWQLSRFYPMIEELIEKLSKGE--LPK 505
Query: 526 EQFPYVKD-KPIELLEADVADSLNTKSTQPTSLRNPRHKAAWAKTTTQPKGNR------- 577
E FP + D P ++ + ++ Q R WAK G
Sbjct: 506 EDFPCMNDPSPSFHGSTSLSSAASSSQGQAAQSMRSRRTPTWAKPRGSDDGYSSDSVLRH 565
Query: 578 ---------QRFFYYVIGGITYSEIKACYDQSKLNNKDVFVGSDSIWTPLQFMANVEDLT 628
QR F +++GG T SE+K C+ S ++V +GS S+ P QF+ ++ LT
Sbjct: 566 ASSDFRKMGQRIFVFIVGGATRSELKVCHKLSTKLKREVILGSTSLDDPPQFITKLKLLT 625
Query: 629 KPREL 633
+L
Sbjct: 626 ANDDL 630
>At4g12120 [U] KOG1300 Vesicle trafficking protein Sec1
Length = 635
Score = 123 bits (308), Expect = 1e-27
Identities = 135/595 (22%), Positives = 253/595 (41%), Gaps = 66/595 (11%)
Query: 63 RKGQSSVEVIYLLKATKFNINCMDADFGNHSIKYKRAHIRFLSEFPRNLVDHFNKRRYLT 122
R+ +++EVIY ++ T+ N+ +D S YK+A + F S R+LV+ K
Sbjct: 69 RQPMTAMEVIYFIQPTEENVTAFLSDMTGKSPLYKKAFVFFSSPVSRSLVNLIKKDMRAM 128
Query: 123 SNVADLKVINCAFTPKEYQYFETLGIDKPLQIFYNPTCKDLVDIGIYKTVQSLLNVCIIT 182
+ LK + F T + ++F + D + + + V
Sbjct: 129 KRIGGLK-----------EGFVTNNENALEELFCDDENHQRADACLNVVAKRIATVLASL 177
Query: 183 GEYPIVRYSEPTAEEYALNEA--TLLPKRVAMAFQQELDDYARDHNDFPPENSRPRAIMV 240
EYP VRY A + L+P ++A + L Y + DFP + ++
Sbjct: 178 KEYPFVRYRGAKALDATTMTTYRELIPTKLAASVWNCLARYKQTIEDFPQTET---CELL 234
Query: 241 ITDRVLDLFSPVLHDFSYQALAYDISKNIDRRTDTYSYKVENETGVMEPKTSRLSDLLDP 300
I DR +D +P++H+++Y A+ +D+ ++ + Y+++V ++TG K L D D
Sbjct: 235 ILDRSIDQIAPLIHEWTYDAMCHDL---LNMEGNKYTHEVPSKTGDKPEKKEVLLDEEDS 291
Query: 301 DWVTMKHFHIVDASEYLTSKVNELIAKNPLLVDRANVKD-----TSDLLNVVAHLKDFDE 355
WV ++ HI DASE L K+ ++KN + + KD + DL +V L + E
Sbjct: 292 IWVELRDAHIADASERLHEKMTNFVSKNKAAQLKHSSKDFGDLSSKDLQKMVHALPQYSE 351
Query: 356 ERRRIALH----RTLLDECFEHSKTCKLAEHAEIEQILAGYGTDFDGEKCKHIS-EKLIE 410
+ +++LH RT+ E L + ++EQ L +G + K +S +I
Sbjct: 352 QIDKLSLHVEIARTINRTIMEQG----LRDLGQLEQDLV-FGDAGRKDVIKFLSTNHIIS 406
Query: 411 HLSDTSSAVT-----------DRVRYIIEYALYRG-GIIDFDFIKLLAFIGVDKSNSWFK 458
H S + ++ R ++E A G ++ + ++LL + + S
Sbjct: 407 HESKLRLIMIVAAIYPKKFEGEKGRKMMELAKLSGDDVVAVNNMRLLGPVHTECKKSTTG 466
Query: 459 HFMQLFKNFNYLGFKLVKDKPKDKPFQKEWTHDTIVNDSTIYQTSRYIPSVGNILGKVIT 518
F F + L+ + K + V ++ +Q SR+ P V ++ K+
Sbjct: 467 SFPLKFDVLKSNIWNLLIHVTQTKRAARR----DRVGETQTWQLSRFYPIVEELVEKLSK 522
Query: 519 NPLLLKEEQFPYVKDKPIELLEADVADSLNTKSTQPTSLRNP----RH--------KAAW 566
L ++ +P + + ++ S P S R P RH +
Sbjct: 523 GH--LPKQDYPCMNEPKPTFYSGSLSPS--ASPVLPHSRRTPTWARRHLSDDGYFSDSVL 578
Query: 567 AKTTTQPKGNRQRFFYYVIGGITYSEIKACYDQSKLNNKDVFVGSDSIWTPLQFM 621
+ ++ K QR F +++GG T SE++ C+ ++ +++V +GS S PL F+
Sbjct: 579 GRASSGFKRKGQRIFVFIVGGATRSELRVCHKLTEKLDREVILGSSSFLDPLTFL 633
>CE17219 [U] KOG1300 Vesicle trafficking protein Sec1
Length = 562
Score = 103 bits (258), Expect = 7e-22
Identities = 126/585 (21%), Positives = 236/585 (39%), Gaps = 94/585 (16%)
Query: 52 VTAVDRIDSPKRKGQSSVEVIYLLKATKFNINCMDADFG-----NHSIKYKRAHIRFLSE 106
VT V+ + + R+ S++ IY++ +I+ + DF N Y+ AHI FL
Sbjct: 56 VTLVEDL-TRNREPMPSMDAIYIISPVAESIDILINDFSRKTKFNPGNSYRSAHIFFLDP 114
Query: 107 FPRNLVDHFNKRRYLTSNVADLKVINCAFTPKEYQYFETLGIDKPLQIFYNPTCKDLVDI 166
L + +K + + LK +N P E Q F T
Sbjct: 115 CCDELFEKLSKSPAVKW-IKTLKELNLNLKPVESQIF---------------TVNSQFRG 158
Query: 167 GIYKTVQSLLNVCIITGEYPIVRYSEPTAEEYALNEATLLPKRVAMAFQQELDDYARDHN 226
+ KT ++++C +P +R+ A+ + +Q+L ++
Sbjct: 159 DMTKTADGIVSLCATLNIHPTLRFQSDFAQS----------SEICQRVEQKLKEFGN--- 205
Query: 227 DFPPENSRPRAIMVITDRVLDLFSPVLHDFSYQALAYDISKNIDRRTDTYSYKVENETGV 286
E A +V+ DR DL SP+LH+ + QA+ D++ D Y Y ++
Sbjct: 206 ----EGMGTDAELVVLDRSFDLVSPLLHEVTLQAMVVDVTAFKD---GVYRYTEAGDSKE 258
Query: 287 MEPKTSRLSDLLDPDWVTMKHFHIVDASEYLTSKVNELIAKNPLLVDRANVKDTS--DLL 344
+ + D D +W+ ++H + + + + V + KN + N+K+ S D
Sbjct: 259 I------VLDEKDQNWLDLRHKLLPEVMKSVNKMVKDF--KNTNKTEPENIKNQSSKDFS 310
Query: 345 NVVAHLKDFDEERRRIALHRTLLDECFEHSKTC-KLAEHAEIEQILAGYGTDFDGEKCKH 403
V L+ + + + ++A + +L +EC SK L + +EQ +A
Sbjct: 311 TTVRTLQPYLKMKAKMAAYISLTEEC--RSKYFDSLEKIIALEQDMA------------- 355
Query: 404 ISEKLIEHLSDTSSAVTDRVRYIIEYALYRGGIIDFDFIKLLAFIGVDKSNSWFKHFMQL 463
E EH+ T S R+ I A+ + I +L IG DK +F +
Sbjct: 356 -VEHTPEHVRITDSQAVGRLSTFILPAIPTETRLRLILIFMLT-IGKDKDEQYFNRLLH- 412
Query: 464 FKNFNYLGFKLVKDKP--KDKPFQKEWTHDTIVNDSTIYQTSRYIPSVGNILGKVITNPL 521
+ F+++K +DK + ++ H + + SR+ P + N++ ++
Sbjct: 413 HTDIPESEFQIIKRMLIWRDKTQKSQFQHRRPPPEDERFIASRWDPKIKNLIEEIY---- 468
Query: 522 LLKEEQFPYVKDKPIELLEADVADSLNTKSTQPTSLRNPRHKAAWAKTTTQPKGNRQRFF 581
++ ++ E VA +T +P + A + +++
Sbjct: 469 -----------ERRLDEREFKVAGKKSTSDFRPAA------SARYGSGLAGKPREKRKII 511
Query: 582 YYVIGGITYSEIKACYDQSKLNNKDVFVGSDSIWTPLQFMANVED 626
+V+GGITYSE++ Y+ SK N V +GSD I TP F+ ++ D
Sbjct: 512 IFVVGGITYSEMRVAYELSKKTNTTVILGSDEILTPSSFLESLRD 556
>At1g02010 [U] KOG1300 Vesicle trafficking protein Sec1
Length = 426
Score = 88.6 bits (218), Expect = 3e-17
Identities = 94/402 (23%), Positives = 181/402 (44%), Gaps = 29/402 (7%)
Query: 239 MVITDRVLDLFSPVLHDFSYQALAYDISKNIDRRTDTYSYKVENETGVMEPKTSRLSDLL 298
++I DR +D +P++H+++Y A+ +D+ +D + + +V ++TG K + +
Sbjct: 27 LLIVDRSVDQIAPIIHEWTYDAMCHDL---LDMEGNKHVIEVPSKTGGPPEKKEIVLEDH 83
Query: 299 DPDWVTMKHFHIVDASEYLTSKVNELIAKNPLLVDRA---NVKDTSDLLNVVAHLKDFDE 355
DP W+ ++H HI DASE L K+ +KN R+ + T DL +V L + E
Sbjct: 84 DPVWLELRHTHIADASERLHEKMTNFASKNKAAQMRSRDGSELSTRDLQKIVQALPQYGE 143
Query: 356 ERRRIALHRTLLDECFEHSKTCKLAEHAEIEQILAGYGTDFDGEKCKHISEKLIEHLSDT 415
+ +++ H L + + L + ++EQ L F K + L + DT
Sbjct: 144 QVDKLSTHVELAGKINRIIRDTGLRDLGQLEQDLV-----FGDAGAKDVINFLRTN-QDT 197
Query: 416 SSAVTDRVRYIIEYA-LYRGGIIDFDFIKLLAFIGVDKSNSWFKHFMQLF----KNFNYL 470
+ +++R ++ YA +Y +KL+ + + MQL +N
Sbjct: 198 NP--ENKLRLLMIYATVYPEKFEGDKGVKLMQLARLSPVDMKVISNMQLIAGSPENKAKS 255
Query: 471 G-FKLVKDKPKDKPFQKEWTHDTIVNDSTIYQTSRYIPSVGNILGKVITNPLLLKEEQFP 529
G F L D K K ++ D + T +Q R+ P + +L K++ L +
Sbjct: 256 GSFSLKFDAGKTKQANRK---DRSGEEET-WQLFRFYPMIEELLEKLVKGDLSKSDY--- 308
Query: 530 YVKDKPIELLEADVADSLNTKSTQPTSLRN--PRHKAAWAKTTTQPKGNRQRFFYYVIGG 587
++ E++ KS+ PT+ + + +T+ K QR F ++IGG
Sbjct: 309 LCMNQSSHKEESEARTGSVRKSSAPTAFISFFTPSDSVLKSASTEFKKLGQRIFVFIIGG 368
Query: 588 ITYSEIKACYDQSKLNNKDVFVGSDSIWTPLQFMANVEDLTK 629
T SE++ C+ + ++V +GS S P Q++ ++ L++
Sbjct: 369 ATRSELRVCHKLTSSLRREVVLGSTSFDDPPQYITKLKLLSE 410
>YDR189w [U] KOG1301 Vesicle trafficking protein Sly1 (Sec1 family)
Length = 666
Score = 73.2 bits (178), Expect = 1e-12
Identities = 144/632 (22%), Positives = 248/632 (38%), Gaps = 98/632 (15%)
Query: 46 NDLLTYVTAVDRIDSPKRKGQSSVEVIYLLKATKFNINCMDADFGNHSIKYKRAHIRFLS 105
NDLL V + R V IY + TK NI+ + D S KY +I F S
Sbjct: 73 NDLLKAGITVHSLIKQDRSPLPDVPAIYFVSPTKENIDIIVNDL--KSDKYSEFYINFTS 130
Query: 106 EFPRNLVDHFNKRRYLTSNVADLKVIN---CAFTPKEYQYFE--------TLGIDKPLQI 154
PRNL++ ++ +T +K + F E + F TL K +
Sbjct: 131 SLPRNLLEDLAQQVSITGKSDKIKQVYDQYLDFIVTEPELFSLEISNAYLTLNDPKTTEE 190
Query: 155 FYNPTCKDLVDIGIYKTVQSLLNVCIITGEYPIVRYSEPTAEEYALNEATLLPKRVAMAF 214
C ++ D G++ TV ++ ++ PI+R ++ E +A
Sbjct: 191 EITGLCANIAD-GLFNTVLTINSI-------PIIRAAKGGPAEI-----------IAEKL 231
Query: 215 QQELDDYARDHND-----FPPENSRPRAIMVITDRVLDLFSPVLHDFSYQALAYDISKNI 269
+L D+ + N +S R +++I DR +D S H + YQ + +DI K +
Sbjct: 232 GTKLRDFVINTNSSSTSTLQGNDSLERGVLIILDRNIDFASMFSHSWIYQCMVFDIFK-L 290
Query: 270 DRRTDTYSYK-VENETG--VMEPKTSRLSDLLDPD--WVTMKHFHIVDASEYLTSKVN-- 322
R T T + EN T +P ++ D+ D W+ H +A+E + + +N
Sbjct: 291 SRNTVTIPLESKENGTDNTTAKPLATKKYDIEPNDFFWMENSHLPFPEAAENVEAALNTY 350
Query: 323 -----ELIAKNPLL----VDRANVKDTSDLLNVVAHLKDFDEERRRIALHRTLLDECFEH 373
E+ K + +D + DT + VV L + ++ I H +
Sbjct: 351 KEEAAEITRKTGVTNISDLDPNSNNDTVQIQEVVKKLPELTAKKNTIDTHMNIFAALLSQ 410
Query: 374 SKTCKLAEHAEIEQILAGYGTDF-------DGEKCKHISEKL----IEHLSDTSSAVTDR 422
++ L E+EQ T DG K ++ +KL + +L+ T+ D
Sbjct: 411 LESKSLDTFFEVEQDPGSTKTRSRFLDILKDG-KTNNLEDKLRSFIVLYLTSTTGLPKDF 469
Query: 423 VRYIIEYALYRGGIIDFDFIKLLAFIGVDKSNSWFKHFMQLFKNFNYLGFKLVKDKPKDK 482
V+ + Y ++ D + +K + + + FMQL N + L
Sbjct: 470 VQNVENY--FKENDYDINALKYVYKL---------REFMQL-SNMSLQNKSL-------- 509
Query: 483 PFQKEWTHDTIVNDSTIYQTSRYIPSVGNILGKVITNPLLLKEEQFPYVKDKPIELLEAD 542
E D+ S + + Y + G + G V + +K + P K PI +
Sbjct: 510 ----EDGSDSAFKPSNLTLSGIYGLTEGKLQGGVGSLISGIK-KLLPEKKTIPITNVVDA 564
Query: 543 VADSLNT--KSTQPT-SLRNPRHKAAWAKTTTQPK-GNRQRFFYYVIGGITYSEIKACYD 598
+ D LN+ K+ + T S K T +PK + + +V+GG Y E + +
Sbjct: 565 IMDPLNSSQKNLETTDSYLYIDPKITRGSHTRKPKRQSYNKSLVFVVGGGNYLEYQNLQE 624
Query: 599 --QSKLNN-KDVFVGSDSIWTPLQFMANVEDL 627
S+L+N K V GS +I TP +F+ + L
Sbjct: 625 WAHSQLHNPKKVMYGSTAITTPAEFLNEISRL 656
>SPCC74.01 [U] KOG1301 Vesicle trafficking protein Sly1 (Sec1 family)
Length = 639
Score = 66.2 bits (160), Expect = 2e-10
Identities = 54/207 (26%), Positives = 95/207 (45%), Gaps = 19/207 (9%)
Query: 63 RKGQSSVEVIYLLKATKFNINCMDADFGNHSIKYKRAHIRFLSEFPRNLVDHFNKRRYLT 122
R+ + V IY ++ T+ NI + D Y+ A++ F S R L++ F + T
Sbjct: 83 RQPIADVPAIYFVQPTQENIELIIEDLSKGL--YESAYVCFSSTISRALLEQFAELASKT 140
Query: 123 SNVADLKVIN---CAFTPKEYQYFETLGIDKPLQIFYNPTCKD-LVDIGIYKTVQSLLNV 178
+ + + + E +F +L + K F+NP+ + L++ + V L +V
Sbjct: 141 NTSHMIHQVYDQYLNYVVLESDFF-SLQLPKIFHTFHNPSSDEALINSRVQDIVNGLFSV 199
Query: 179 CIITGEYPIVRYSEPTAEEYALNEATLLPKRVAMAFQQELDDYARDHND-FPPENSRPRA 237
+ G PI+R + +A E VA Q L D+ + D F N +PR
Sbjct: 200 IVTLGTIPIIRCPQGSAAEM-----------VAQKLNQRLKDHLMNTKDAFVSVNPKPRP 248
Query: 238 IMVITDRVLDLFSPVLHDFSYQALAYD 264
I+++ DR +DL + H ++YQAL +D
Sbjct: 249 ILILLDRTVDLIPMINHSWTYQALIHD 275
>Hs7706407 [U] KOG1301 Vesicle trafficking protein Sly1 (Sec1 family)
Length = 638
Score = 62.8 bits (151), Expect = 2e-09
Identities = 85/389 (21%), Positives = 157/389 (39%), Gaps = 42/389 (10%)
Query: 69 VEVIYLLKATKFNINCMDADFGNHSIKYKRAHIRFLSEFPRNLVDHFNKRRYLTSNVADL 128
V +Y + T+ NI+ M D N Y+ ++ F+S R+ ++ S V +
Sbjct: 83 VPAVYFVMPTEENIDRMCQDLRNQL--YESYYLNFISAISRSKLEDIANAALAASAVTQV 140
Query: 129 -KVIN--CAFTPKEYQYFETLGIDKPLQIFYNPTCKDLVDIGIYKTVQSLLNVCII---- 181
KV + F E F +K L + D+ D + + ++++
Sbjct: 141 AKVFDQYLNFITLEDDMFVLCNQNKELVSYRAINRPDITDTEMETVMDTIVDSLFCFYGT 200
Query: 182 TGEYPIVRYSEPTAEEYALNEATLLPKRVAMAFQQELDDYARDHNDFPPENSRPRAIMVI 241
G+ PI+R S TA E A L K++ + + + S R ++V+
Sbjct: 201 RGDVPIIRCSRGTAAEMV---AVKLDKKLRENLRDARNSLFTGDTLGAGQFSFQRPLLVL 257
Query: 242 TDRVLDLFSPVLHDFSYQALAYDI-SKNIDRRTDTYSYKVENETGVMEP--KTSRLSDL- 297
DR +DL +P+ H ++YQAL +D+ +++R S VEN P K + DL
Sbjct: 258 VDRNIDLATPLHHTWTYQALVHDVLDFHLNRVNLEESSGVENSPAGARPKRKNKKSYDLT 317
Query: 298 -LDPDWVTMKHFHIVDASEYLTSKVNELIAKNPLLVDRANV---------------KDTS 341
+D W K + +E + ++ A+ + ++ +T+
Sbjct: 318 PVDKFWQKHKGSPFPEVAESVQQELESYRAQEDEVKRLKSIMGLEGEDEGAISMLSDNTA 377
Query: 342 DLLNVVAHLKDFDEERRRIALHRTLLDECFEHSKTCKLAEHAEIEQILAGYGTDFDGEKC 401
L + V+ L + E++R I LH + EH K KL + E E+ + T
Sbjct: 378 KLTSAVSSLPELLEKKRLIDLHTNVATAVLEHIKARKLDVYFEYEEKIMSKTT------- 430
Query: 402 KHISEKLIEHLSDTSSAV-TDRVRYIIEY 429
+ + L++ +SD + D +R + Y
Sbjct: 431 --LDKSLLDIISDPDAGTPEDNMRLFLIY 457
>Hs7706371 [U] KOG1301 Vesicle trafficking protein Sly1 (Sec1 family)
Length = 640
Score = 62.4 bits (150), Expect = 2e-09
Identities = 87/389 (22%), Positives = 158/389 (40%), Gaps = 42/389 (10%)
Query: 69 VEVIYLLKATKFNINCMDADFGNHSIKYKRAHIRFLSEFPRN-LVDHFNKRRYLTSNVAD 127
V +Y + T+ NI+ M D N Y+ ++ F+S R+ L D N L++
Sbjct: 84 VPAVYFVMPTEENIDRMCQDLRNQL--YESYYLNFISAISRSKLEDIANAALELSAVTQV 141
Query: 128 LKVIN--CAFTPKEYQYFETLGIDKPLQIFYNPTCKDLVDIGIYKTVQSLLNVCII---- 181
KV + F E F +K L + D+ D + + ++++
Sbjct: 142 AKVFDQYLNFITLEDDMFVLCNQNKELVSYRAINRPDITDTEMETVMDTIVDSLFCFYGT 201
Query: 182 TGEYPIVRYSEPTAEEYALNEATLLPKRVAMAFQQELDDYARDHNDFPPENSRPRAIMVI 241
G PI+R S TA E A L K++ + + + S R ++V+
Sbjct: 202 LGAVPIIRCSRGTAAEMV---AVKLDKKLRENLRDARNSLFTGDTLGAGQFSFQRPLLVL 258
Query: 242 TDRVLDLFSPVLHDFSYQALAYDI-SKNIDRRTDTYSYKVENETGVMEP--KTSRLSDL- 297
DR +DL +P+ H ++YQAL +D+ +++R S VEN P K + DL
Sbjct: 259 VDRNIDLATPLHHTWTYQALVHDVLDFHLNRVNLEESSGVENSPAGARPKRKNKKSYDLT 318
Query: 298 -LDPDWVTMKHFHIVDASEYLTSKVNELIAKNPLLVDRANV---------------KDTS 341
+D W K + +E + ++ A+ + ++ +T+
Sbjct: 319 PVDKFWQKHKGSPFPEVAESVQQELESYRAQEDEVKRLKSIMGLEGEDEGAISMLSDNTA 378
Query: 342 DLLNVVAHLKDFDEERRRIALHRTLLDECFEHSKTCKLAEHAEIEQILAGYGTDFDGEKC 401
L + V+ L + E++R I LH + EH K KL + E E+ + T
Sbjct: 379 KLTSAVSSLPELLEKKRLIDLHTNVATAVLEHIKARKLDVYFEYEEKIMSKTT------- 431
Query: 402 KHISEKLIEHLSDTSSAV-TDRVRYIIEY 429
+ + L++ +SD + D++R + Y
Sbjct: 432 --LDKSLLDIISDPDAGTPEDKMRLFLIY 458
Database: KOG eukaryal database 04/03
Posted date: Apr 14, 2003 1:07 PM
Number of letters in database: 30,389,216
Number of sequences in database: 60,738
Lambda K H
0.319 0.136 0.396
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 42,699,596
Number of Sequences: 60738
Number of extensions: 1926093
Number of successful extensions: 4991
Number of sequences better than 1.0e-05: 15
Number of HSP's better than 0.0 without gapping: 3
Number of HSP's successfully gapped in prelim test: 12
Number of HSP's that attempted gapping in prelim test: 4928
Number of HSP's gapped (non-prelim): 22
length of query: 701
length of database: 30,389,216
effective HSP length: 113
effective length of query: 588
effective length of database: 23,525,822
effective search space: 13833183336
effective search space used: 13833183336
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)