ORF STATUS Function Best COG Functional category Pathways and functional systems
r_klactIV4299 good D KOG2260 Cell cycle control, cell division, chromosome partitioning Cell division cycle 37 protein, CDC37
Only best alignment is shown:
BLASTP 2.2.3 [May-13-2002]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= r_klactIV4299 1460573 1462057 495
(495 letters)
Database: KOG eukaryal database 04/03
60,738 sequences; 30,389,216 total letters
Searching..................................................done
Color Key for Alignment Scores: 
Score E
Sequences producing significant alignments: (bits) Value
YDR168w [D] KOG2260 Cell division cycle 37 protein CDC37 493 e-139
SPBC9B6.10 [D] KOG2260 Cell division cycle 37 protein CDC37 209 1e-53
CE14726 [D] KOG2260 Cell division cycle 37 protein CDC37 60 1e-08
>YDR168w [D] KOG2260 Cell division cycle 37 protein CDC37
Length = 506
Score = 493 bits (1270), Expect = e-139
Identities = 257/511 (50%), Positives = 357/511 (69%), Gaps = 21/511 (4%)
Query: 1 MAIDYSKWDKXXXXXXXXXXVHPNVDKRSFIKWKQQSIHQEREKRKSDIANLEFQLEMYN 60
MAIDYSKWDK VHPNVDK+SFIKWKQQSIH++R KR DI NLE Q++MY+
Sbjct: 1 MAIDYSKWDKIELSDDSDVEVHPNVDKKSFIKWKQQSIHEQRFKRNQDIKNLETQVDMYS 60
Query: 61 HLNKRVDKLMIQLKDDDLISKDSVSKFLNENFDKTEKGSGENVDPDLPPYNEMVLDLFEQ 120
HLNKRVD+++ L + L +V+KFLN NFDK EK GENVDP++ YNEMV DLFEQ
Sbjct: 61 HLNKRVDRILSNLPESSLTDLPAVTKFLNANFDKMEKSKGENVDPEIATYNEMVEDLFEQ 120
Query: 121 LERNAKNDNKDPKDGAVIREELMKHRAKIAAVSKEAEEKLKQLYIEKSMHISSEDVHTGF 180
L ++ + KD K ++IR+ ++KHRAKI +V+ EA++KL +LY EK+ HISSED+HTGF
Sbjct: 121 LAKDLDKEGKDSKSPSLIRDAILKHRAKIDSVTVEAKKKLDELYKEKNAHISSEDIHTGF 180
Query: 181 DKGFINAAKE-----DAPVPDYLKDASTNQV--ALPKPKIQP--IDYKDDILKIAPETEK 231
D F+N K +A + L A+ + + L K + ID+KDD +K+A ETE+
Sbjct: 181 DSSFMNKQKGGAKPLEATPSEALSSAAESNILNKLAKSSVPQTFIDFKDDPMKLAKETEE 240
Query: 232 FGSIQPGNYAEAEKFLLEHPQILSEQQKDALMMSAFEHEMSGNTQRAYQVIHQSELLSYL 291
FG I Y++++KFLLEH I+SEQQKDALMM AFE+++ G+ + QVIHQSEL++Y+
Sbjct: 241 FGKISINEYSKSQKFLLEHLPIISEQQKDALMMKAFEYQLHGDDKMTLQVIHQSELMAYI 300
Query: 292 LEIYAMKKLPDFNVSQMKEVIEMFFERLFSPRSNPMAKKSFLESVQTKYEHVKTRSKAMQ 351
EIY MKK+P N ++ VI MFFE++ + PM K+SFL SVQ K+ H++ RSK +Q
Sbjct: 301 KEIYDMKKIPYLNPMELSNVINMFFEKVIFNKDKPMGKESFLRSVQEKFLHIQKRSKILQ 360
Query: 352 EE--SDGEGEGVETIQLKSLDNSAELQVNLPDFSSSEPGEVAKVQAFNKL-PPKMQEAVK 408
+E + EGVETIQLKSLD+S EL+VNLPDF+S +P E+ KV+ F L P KMQEA+
Sbjct: 361 QEEMDESNAEGVETIQLKSLDDSTELEVNLPDFNSKDPEEMKKVKVFKTLIPEKMQEAIM 420
Query: 409 SQNLDAINAVFAELPMDKAEQILDIFHEGGIIGINAVLEDENEFKELQEHYQNDQ---GI 465
++NLD IN VF ++P+++AE++L++F++ IIGI A+LE+E +F+ L++ Y+ D +
Sbjct: 421 TKNLDNINKVFEDIPIEEAEKLLEVFNDIDIIGIKAILENEKDFQSLKDQYEQDHEDATM 480
Query: 466 ENLTIQEVE-DTDEHKEADDAVPISSADIVD 495
ENL++ + + D H+E +AD VD
Sbjct: 481 ENLSLNDRDGGGDNHEEVK-----HTADTVD 506
>SPBC9B6.10 [D] KOG2260 Cell division cycle 37 protein CDC37
Length = 466
Score = 209 bits (531), Expect = 1e-53
Identities = 134/480 (27%), Positives = 243/480 (49%), Gaps = 57/480 (11%)
Query: 1 MAIDYSKWDKXXXXXXXXXXVHPNVDKRSFIKWKQQSIHQEREKRKSDIANLEFQLEMYN 60
MAIDYSKWDK VHPNVDK+SFI+W+Q+ IH++R RK + +++ + M
Sbjct: 1 MAIDYSKWDKLELSDDSDIEVHPNVDKKSFIRWRQRDIHEKRAVRKQKMEDIKGAMAMNR 60
Query: 61 HLNKRVDKLMIQLKDDDLISKDSVSK--FLNENFDKTEKGSGENVDPDLP---PYNEMVL 115
L R+ ++ + ++ K+S S L +F + +K E++D +P Y+ M++
Sbjct: 61 RLLSRISEM------ETVLEKESPSDPYVLLGSFLEAKKS--EDMDSAIPGGMSYHHMLM 112
Query: 116 DLFEQL-ERNAKNDNKDPKDGAVIREELMKHRAKIAAVSKEAEEKLKQLYIEKSMHISSE 174
L + + + + K D L H+ ++ + ++A+++ L E +I+SE
Sbjct: 113 SLLKVIKDAEDTTEEKSMDDSDKCLRRLKSHKERLLKLLEDAQKEYDTLEAESKNYITSE 172
Query: 175 DVHTGFDKGFINAAKEDAP------------------------VPDYLKDASTNQVALPK 210
D+H GFD ++ + + P P + AST PK
Sbjct: 173 DLHLGFDSTYVQKKEPEKPKKTKTKKETIQVIESLNNPTPPTDFPGAKEQASTGNA--PK 230
Query: 211 PKIQPIDYKDDI-LKIAPETEKFGSIQPGNYAEAEKFLLEHPQILS-EQQKDALMMSAFE 268
+ + +D+ L ++ + +KF +I G+Y+ +E+FL EH IL+ E++ DA+++ AF
Sbjct: 231 NPVNENESEDEEGLSLSEDGKKFANIDFGDYSSSEEFLKEHLNILADEEESDAILLEAFN 290
Query: 269 HEMSGNTQRAYQVIHQSELLSYLLEIYAMKKLPDFNVSQMKEVIEMFFERLFSPRSNPMA 328
E+ G A Q +HQ+ L+SY ++ + +FF+++ P N +
Sbjct: 291 AELEGKPSLAKQYVHQALLISYCRQLGP-------------NGLSIFFQKIKDP--NHQS 335
Query: 329 KKSFLESVQTKYEHVKTRSKAMQEESDGEGEGVETIQLKSLDNSAELQVNLPDFSSSEPG 388
++ FLE V Y + RS A+ +E GEGVE IQL ++D + +L + +P+ S++P
Sbjct: 336 QRLFLEDVHNTYVRIHERSAAISKEQAESGEGVEQIQLCAVDPNTKLSITIPEAGSTDPE 395
Query: 389 EVAKVQAFNKLPPKMQEAVKSQNLDAINAVFAELPMDKAEQILDIFHEGGIIGINAVLED 448
AF PP +Q+A+ + +LD IN V ++ ++ AE++++ G++ I + D
Sbjct: 396 TQKARAAFESFPPNLQKALMTNDLDKINVVLGKMAVENAEEVVEKLSSTGMLSIEEGIID 455
>CE14726 [D] KOG2260 Cell division cycle 37 protein CDC37
Length = 370
Score = 59.7 bits (143), Expect = 1e-08
Identities = 84/422 (19%), Positives = 154/422 (35%), Gaps = 103/422 (24%)
Query: 1 MAIDYSKWDKXXXXXXXXXXVHPNVDKRSFIKWKQQSIHQEREKRKSDIANLEFQLEMYN 60
M IDYSKW K HPN+D S +W+ HQ R +R ++
Sbjct: 1 MPIDYSKW-KDIEVSDDEDDTHPNIDTPSLFRWR----HQARLERMAE------------ 43
Query: 61 HLNKRVDKLMIQLKDDDLISKDSVSKFLNENFDKTEKGSGENVDPDLPPYNEMVLDLFEQ 120
K E DK EKG+ E+
Sbjct: 44 ------------------------KKMEQEKIDK-EKGTTSKK--------------MEE 64
Query: 121 LERNAKNDNKDPKDGAVIREELMKHRAKIAAVSKEAEEKLKQLYIEKSMHISSEDV---- 176
LE+ K D D + I++++ + +A+ A K+ E +E+ + +V
Sbjct: 65 LEK--KLAAADVTDKSDIQKQIDEVKAQEEAWRKKEAE------LEEKERLEPWNVDTIG 116
Query: 177 HTGFDKGFINAAKEDAPVPDYLKDASTNQVALPKPKIQPIDYKDDILKIAPETEKFGSIQ 236
H F IN E P + T+ ++ + + K +LK ++
Sbjct: 117 HEAFSTSRINKITEKKPQAPKTDEEDTHAMSTFFETHESLLEKMAVLKNGAKS------- 169
Query: 237 PGNYAEAEKFLLEHPQILSEQQKDALMMSAFEHEMSGNTQRAYQVIHQSELLSYLLEIYA 296
E FL EHP + SE + L + A + N ++ + Q ++ YLLE+
Sbjct: 170 ------TELFLAEHPHMASEYTANWLTIEALNAAIDFNEEKMKTMAEQCIIIQYLLELSK 223
Query: 297 MKKLPDFNVSQMKEVIEMFFERLFSPRSNPMAKKSFLESVQTKYEHVKTRSKAMQEESDG 356
N + K+ + F + P+ K + + V+ + ++TR++ ++ +
Sbjct: 224 SLNAVATNTTVQKQFFKKF------EAAEPVYMKHYQDEVKAFEDRLRTRAQTKRDAAME 277
Query: 357 EGEGVETIQLKSLDNSAELQVNLPDFSSSEPGEVAKVQAFNKLPPKMQEAVKSQNLDAIN 416
E E E + S PG + + F +LP +M++ ++ +++A+
Sbjct: 278 EAEAEEKAER----------------MKSAPGGIDPQEVFEQLPEEMRKCFEAHDIEALK 321
Query: 417 AV 418
V
Sbjct: 322 GV 323
Database: KOG eukaryal database 04/03
Posted date: Apr 14, 2003 1:07 PM
Number of letters in database: 30,389,216
Number of sequences in database: 60,738
Lambda K H
0.311 0.130 0.354
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 29,857,908
Number of Sequences: 60738
Number of extensions: 1342692
Number of successful extensions: 4483
Number of sequences better than 1.0e-05: 3
Number of HSP's better than 0.0 without gapping: 2
Number of HSP's successfully gapped in prelim test: 1
Number of HSP's that attempted gapping in prelim test: 4471
Number of HSP's gapped (non-prelim): 5
length of query: 495
length of database: 30,389,216
effective HSP length: 110
effective length of query: 385
effective length of database: 23,708,036
effective search space: 9127593860
effective search space used: 9127593860
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.8 bits)