ORF STATUS Function Best COG Functional category Pathways and functional systems
r_klactIV4512 good BDL KOG1020 Cell cycle control, cell division, chromosome partitioning Sister chromatid cohesion protein SCC2/Nipped-B
r_klactIV4512 good BDL KOG1020 Chromatin structure and dynamics Sister chromatid cohesion protein SCC2/Nipped-B
r_klactIV4512 good BDL KOG1020 Replication, recombination and repair Sister chromatid cohesion protein SCC2/Nipped-B
Only best alignment is shown:
BLASTP 2.2.3 [May-13-2002]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= r_klactIV4512 1533582 1538021 1480
(1480 letters)
Database: KOG eukaryal database 04/03
60,738 sequences; 30,389,216 total letters
Searching..................................................done
Color Key for Alignment Scores: 
Score E
Sequences producing significant alignments: (bits) Value
YDR180w [BDL] KOG1020 Sister chromatid cohesion protein SCC2/Nip... 694 0.0
SPAC31A2.05c [BDL] KOG1020 Sister chromatid cohesion protein SCC... 122 3e-27
Hs7661842 [BDL] KOG1020 Sister chromatid cohesion protein SCC2/N... 92 8e-18
Hs19718749 [BDL] KOG1020 Sister chromatid cohesion protein SCC2/... 92 8e-18
7289131 [BDL] KOG1020 Sister chromatid cohesion protein SCC2/Nip... 70 2e-11
CE27255 [BDL] KOG1020 Sister chromatid cohesion protein SCC2/Nip... 64 2e-09
At5g15540 [BDL] KOG1020 Sister chromatid cohesion protein SCC2/N... 56 4e-07
>YDR180w [BDL] KOG1020 Sister chromatid cohesion protein SCC2/Nipped-B
Length = 1493
Score = 694 bits (1792), Expect = 0.0
Identities = 454/1505 (30%), Positives = 767/1505 (50%), Gaps = 51/1505 (3%)
Query: 5 FPGETDNEIPKRISETLKYQPINHIVPKSGLSNLLSS----SITEDISISCNSAFGSPPS 60
+PG+ D IP RI E L+ P++++VPK GL+ L+++ S+ D +I ++ G +
Sbjct: 3 YPGK-DKNIPGRIIEALEDLPLSYLVPKDGLAALVNAPMRVSLPFDKTIFTSADDGRDVN 61
Query: 61 EHWL-YPHPIDFDPFNEGDRDPILFRRPNNITLRDESQETAPDLKLLKNLPQLGIRCL-T 118
+ L + NE +++ ++F+RP+N T S + P L+ L L L T
Sbjct: 62 INVLGTANSTTSSIKNEAEKERLVFKRPSNFTSSANSVDYVPT-NFLEGLSPLAQSVLST 120
Query: 119 VTSLVDSASIV--ANVAGNQNTATKKRRLEAGEDKVLLNELDSKRIQICVQSNPMNDLEV 176
L DS +I + + K + + + N+ S + M +
Sbjct: 121 HKGLNDSINIEKKSEIVSRPEAKHKLESVTSNAGNLSFNDNSSNKKTKTSTGVTMTQANL 180
Query: 177 GKLCLDHLSKLLDSVGLNSEGSVNENAKFWKPLGDV-YVATSEAIDAISLTINKVLGFPM 235
+ L+ L +LD VG + + N ++W L + +V T+ + + +TI + P
Sbjct: 181 AEQYLNDLKNILDIVGFDQNSAEIGNIEYWLQLPNKKFVLTTNCLTKLQMTIKNITDNPQ 240
Query: 236 VFEYIDVQSLKKILGLCTRNIKRILAYQSDNESESLDLNNLTFGCAFLILEVMMIDLKSA 295
+ I++ L ++L + NIK + +S+ L + ++ + ++ +
Sbjct: 241 LSNSIEITWLLRLLDVMVCNIKFSKSSLKMGLDDSM-LRYIALLSTIVLFNIFLLGKNDS 299
Query: 296 NLQLEEYYNAVFSALDNALEKLHVSDNSRG-INADIGNIFLFINLLEKFVASQSYLDEMF 354
NL E Y + L + +E L + G + + + LL K++ + +LD+
Sbjct: 300 NLHRESYIMEPVNFLSDLIESLKILTIEYGSLKIEFDTFQEALELLPKYIRNGPFLDDNV 359
Query: 355 LIKSVCICCDMLLHRCYQHLNTNVLLSQAERIKDLSLGILISLFSEYPSQRLFITEELLS 414
K V I D+L++ + S + +K +S IL+SLF + QR FI EELLS
Sbjct: 360 TAKLVYIFSDLLMNNDIEATTNIQFQSFWDNVKRISSDILVSLFGSFDQQRGFIIEELLS 419
Query: 415 HVHDIXXXXXXXXXXXXDEFENGYASYFTVALVAMFQSINALPDAELLSDFTSELLENVL 474
H+ + +N Y + FT L++M ++IN + D E ++ +
Sbjct: 420 HIEKLPTKRIQKKLRKVGN-QNIYITDFTFTLMSMLENINCYSFCNQMKDIAPENIDLLK 478
Query: 475 SENNAASLELKGLIDNVTTTLFEGLITNPFKFKSIVEIYIQDLLTMIGNPKWAYSHHLLE 534
+E L +++++ T+ E NP + +++ ++QDLL +I +P+W + +L
Sbjct: 479 NEYKKQEEFLFNIVEHINDTILERFFKNPSALRYVIDNFVQDLLLLISSPQWPVTEKILS 538
Query: 535 AFLPKLFQIFSPTYQGTGNFEVLAIQLVGQITATLTDVKLRAASEESRDVKRIFNLQN-- 592
+ L +L ++SP+ Q + N E + +QL+G I +T+ D+K E ++ ++ N
Sbjct: 539 SLLKRLLSVYSPSMQVSANIETICLQLIGNIGSTIFDIKCSTRDHEDNNLIKMINYPETL 598
Query: 593 -----EYKECFDWLGSQTKTYFSDRALWNESLFYISEMLDQKEIDKTDAQVMNFVIRIIA 647
++EC + + + R LWN L +L +E K DA+ +I +
Sbjct: 599 PHFFKSFEECIAYNETIKCRRSATRFLWNLRL---GTILILEEYTK-DAKEQ--IITVDN 652
Query: 648 XXXXXXXXXXXXXXXXXXNNGIDGNERVRSLYMKIVSLSPLFNFYEPALRLILSLLDQQK 707
N ++ Y I+ L N Y+P L+LILSLL + K
Sbjct: 653 ELKKILEQIKDGGLGPELENREADFSTIKLDYFSILHAFELLNLYDPYLKLILSLLAKDK 712
Query: 708 VKLKSGAVKCLTLLVSKDPQMLDTPFVQETIKNRLYDSSASVRDAILDLLEQATTYIQFY 767
+KL+S A+KCL++L SKD +L P V+ETI RL DSSASV+DAILDL+ ++Y +FY
Sbjct: 713 IKLRSTAIKCLSMLASKDKVILSNPMVKETIHRRLNDSSASVKDAILDLVSINSSYFEFY 772
Query: 768 REINCNFDDDSIAVRKHVMRMNEKILDTSSDLKIKTFVLEKVLRRIEDEEDVIVENARKX 827
++IN N++DDSI VRKHV+R+NEK+ D ++D+ K +V+ ++L +IEDEED I++ AR
Sbjct: 773 QQINNNYNDDSIMVRKHVLRINEKMYDETNDIVTKVYVIARILMKIEDEEDNIIDMARLI 832
Query: 828 XXXX-XXXXXSASDLSVKLHRFDXXXXXXXXXXXIGYGGKTXXXXXXXXXXXXXNPSIHK 886
D KL I K N H
Sbjct: 833 LLNRWILKVHEVLDQPEKLKEISSSVLLVMSRVAI-MNEKCSQLFDLFLNFYLLNKEAHS 891
Query: 887 NEDTKSIFDALRNLVNVLIEEITENAASADELSESNA----RNRYDLLYFFANCPINFIS 942
E I L L + L+++I E ++D+ +E N+ +N +LL FA+ ++F++
Sbjct: 892 KEAYDKITHVLTILTDFLVQKIVE--LNSDDTNEKNSIVDKQNFLNLLAKFADSTVSFLT 949
Query: 943 KPHLYSLFPYLSSNFNGKCYLLLLKVFRSCIKKHSNIKLKFLHDLETTLLAKLSKLNTRE 1002
K H+ +L+PY+ S+ + +L+VFR +K +N K KFL+DLETTLL++L K+N RE
Sbjct: 950 KDHITALYPYMVSDEKSDFHYYILQVFRCTFEKLANFKQKFLYDLETTLLSRLPKMNVRE 1009
Query: 1003 IEEALAICWETSTKTRKEDKLLKVCASCIEQLRPYVTQAVTAPSSLKLDGKVQRLIYLCT 1062
I+EA+ + W +T ++ K C+SC+ L PY+ +A +++ +DGK+QRLIYL T
Sbjct: 1010 IDEAMPLIWSVATHRHDTARVAKACSSCLSHLHPYINKANNEEAAIVVDGKLQRLIYLST 1069
Query: 1063 GFARMCHFKENEKRLEFLRGDEHLYQYVTKCLLTFTNKKLATPLRKIAIKNLVKLASSFP 1122
GFAR C K + ++ FL+ E LY+++TKCLL + K+ +R++A+KNL KL + P
Sbjct: 1070 GFARFCFPKPSNDKIAFLQEGETLYEHITKCLLVLSKDKITHVIRRVAVKNLTKLCGNHP 1129
Query: 1123 KLFNSPPVLKVLDHEFEAGVLDTKLTIIDCLQVFFSSEEKKVLMKIGANGTISSSSEMRR 1182
KLFNS VL +LD EF++ LD KL I++ L F EE+K + G N T+SS+S +++
Sbjct: 1130 KLFNSRHVLHLLDKEFQSDQLDIKLVILESLYDLFLLEERKSVRNTGVNSTLSSNSILKK 1189
Query: 1183 LISTQNTTESVNDGVCSALVTRYLDSIMDLCLLSDIKDAIVAIKFLQLTLNFHYTNPSHA 1242
+ N E NDGVCSAL TR+LD+I+ LCLL D+K+++VAI+ L+L L F YTNPSH+
Sbjct: 1190 KLLKTNRVEFANDGVCSALATRFLDNILQLCLLRDLKNSLVAIRLLKLILKFGYTNPSHS 1249
Query: 1243 VPTLIALSCSDANSVKTVSTRLLSTIFEQYESMVFNGLAAGFKKCCVVFKSLLPSELERK 1302
+PT+IAL S + ++ V+ LL +FE+YE++VF+ L+ G K +
Sbjct: 1250 IPTVIALFASTSQYIRHVAYELLEDLFEKYETLVFSSLSRGVTKAIHYSIHTDEKYYYKH 1309
Query: 1303 DHCMKRLQCILSNNKKNGKKYVSVVKNL------TISECYKTHSVSNTELLFLLHNMSQI 1356
DH + L+ + KKNG K+ V+K + I++ T+S + L N+S I
Sbjct: 1310 DHFLSLLEKLCGTGKKNGPKFFKVLKRIMQSYLDDITDLTSTNSSVQKSIFVLCTNISNI 1369
Query: 1357 DYGDSYELYEFLSTMSLVIDEIDETIQD-----ILSIQEDDEKNSKAFSLIKRRKIMSNF 1411
+ Y+L L T+ L D + E I D + S+ +EK S +I + + +
Sbjct: 1370 TFVSQYDLVSLLKTIDLTTDRLKEVIMDEIGDNVSSLSVSEEKLS---GIILIQLSLQDL 1426
Query: 1412 KTHMISIHNLSSEKLSFIGTPEEATLKGRSISTISDSPLAIESIVFENLTNEEIDQQCLE 1471
T+++ ++ L + L + EE+ LK + + ++ S EN+ + + L
Sbjct: 1427 GTYLLHLYGLRDDVL-LLDIVEESELKNKQLPA-KKPDISKFSAQLENIEQYSSNGKLLT 1484
Query: 1472 YQKEY 1476
Y +++
Sbjct: 1485 YFRKH 1489
>SPAC31A2.05c [BDL] KOG1020 Sister chromatid cohesion protein SCC2/Nipped-B
Length = 1583
Score = 122 bits (307), Expect = 3e-27
Identities = 236/1160 (20%), Positives = 461/1160 (39%), Gaps = 129/1160 (11%)
Query: 216 TSEAIDAISLTINKVLGFPMVFEYIDVQSLKKILGLCTRNIKR--ILAYQSDNESESL-D 272
+S AI+ + + + K+ + ++ S+ + + + +K + Y N +SL
Sbjct: 256 SSHAIEKLYMALTKLSRLGACDKLLEEGSIILVKQILEKELKELPVACYSIINLHDSLTQ 315
Query: 273 LNNLTF---------GCAFLILEVMMIDLKSANLQLEEYYNAVFS-ALDNALEKLHVSDN 322
NL F FL+ + + + L L +++F + A++ + S
Sbjct: 316 FPNLDFILKTTALVLFIIFLVPSFKKLQNEESILHLLNILHSIFEYTVPEAIDNIVQSKT 375
Query: 323 SRGINADIGNIFLFI-------NLLEKFVASQSYLDEMFLIKSVCICCDM-LLHRCYQHL 374
S ++I ++ + + N+L K VA + L E +I+ V + + L ++
Sbjct: 376 SDARTSEIQHLSVLLQKVANVLNILSK-VAHEIPLSEAVVIRIVYLFPKVSTLDNSFKTK 434
Query: 375 NTNVLLSQAERIKDLSLGILISLFSEYPSQRLFITEELLSHVHDIXXXXXXXXXXXXDEF 434
N S + +K L LF YP QR FI EE L++ +
Sbjct: 435 LPNCNSSSFDFLKAPLFQTLQYLFRLYPYQRDFIIEESLTNFSHLPTARSVSRTY---RL 491
Query: 435 ENGYA-SYFTVALVAMFQS--INALPDAELLS------------DFTSEL--LENVLSEN 477
NG + Y++ V + QS I L D+E++ + T L +E++LS++
Sbjct: 492 SNGKSIQYYSTLFVRLIQSCSIQNLFDSEIVQSESKSTEALHSGNLTEHLKTVESILSKS 551
Query: 478 NAASLELKGLIDN--VTTTLFEGLITNPFKFKSIVEIYIQDLLTMIGNPKWAYSHHLLEA 535
+ I ++ +L + + F + +I ++DLL M+ P+W + ++
Sbjct: 552 RHEEYRIANHIVAYLLSRSLKQNKTESDNSFAILTKILLEDLLNMLSLPEWCGTETIIRQ 611
Query: 536 FLPKLFQIFSPTYQGTGNFEVLAIQLVGQITATLTDVKLRAASEESRDVKRIFNLQNEYK 595
F L + Q + A+ L+ I K+ A + S K +
Sbjct: 612 FAMNLVMTVTNDKQAVSSKNA-ALDLISLIVN-----KVLALFDLSLFEKHNIPAPTNFN 665
Query: 596 ECFDWLGSQTKTYFSDRALWNESLF------------------YISEMLDQKEIDKTDAQ 637
+ ++ S T+ + +N F + S +L +++ D++
Sbjct: 666 DIISFIPSITRLNELSQVSFNHFYFLCKGDISLENILPYNYNKWFSFLLQLRKVCN-DSE 724
Query: 638 VMNFVIRIIAXXXXXXXXXXXXXXXXXXNNGIDGNERVRSLYMKIVSLSPLFNFYEPALR 697
+ + I + +E +++ + S LF + +
Sbjct: 725 ALKIIDNCI------DKNMQKSQEGFQGPSPFKADENDEDIFIISLYHSSLFLNLKFFVS 778
Query: 698 LILSLLDQQKVKLKSGAVKCLTLL--VSKDPQMLDT-PFVQETIKNRLYDSSASVRDAIL 754
LI+ LD + L++ KCL ++ + P +L T P V I ++ D SA VRD +L
Sbjct: 779 LIIGFLDSPQASLRT---KCLRIINQMKTIPSILRTHPEVLAQIISKSNDQSAIVRDTVL 835
Query: 755 DLLEQATTYIQFYRE--------INCNFDDDSIAVRKHVMRMNEKILDTSSDLKIKTFVL 806
DLL TYI YRE I D S VRK ++ ++ + + DL I+ +
Sbjct: 836 DLLG---TYIMAYRETIPQIYGCIISGISDPSTIVRKRAIKQLCEVYEATEDLNIRVDIA 892
Query: 807 EKVLRRIEDEEDVI----VENARKXXXXXXXXXXSASDLSVKLHRFDXXXXXXXXXXXIG 862
K+L R DEE+ I +E K +L + +
Sbjct: 893 SKLLTRSNDEEETISELSLEVLEKLWFSPASNELDCQKGYEQLTFLEKQKLRVQYFPILK 952
Query: 863 YGGKTXXXXXXXXXXXXXNPSIHKNE-DTKSIFDALRNLVNVLIEEITENAASADELSES 921
+ K E + ++ +R L++ L ++ E + D++ ES
Sbjct: 953 LCAEPSTERHVLLVTSLKTMLTSKEEINLSTLHTQIRLLLSCLFNQLIE-VVTEDQVDES 1011
Query: 922 NARNRYDL---LYFFANCPINFISKPHLYSLFPYL--SSNFNGKCYLL-LLKVFRSCIKK 975
Y++ L+ F+ +L+ L PYL +S + +L ++ +FR +
Sbjct: 1012 TKGILYEIMSTLFVFSRAFPFLFDLSYLHLLKPYLRSASTIEEQRFLYYVVAIFRQVLPF 1071
Query: 976 HSNIKLKFLHDLETTLLAKLSKLNTREIEEALAICWETSTKTRKEDKLLKVCASCIEQLR 1035
I FL LE+ LL +L+K T + E + T+ ++L K+ SC++ L
Sbjct: 1072 QKEISESFLRSLESVLLQRLTKAGTATLMEIVPCLCSLFTRLNDYERLKKIVVSCLKSLE 1131
Query: 1036 PYVTQAVTAPSSLKLDGKVQRLIYLCTGFARMCHFKENEKR-LEFLRGDEH-----LYQY 1089
+A + ++ + ++ LI L + + + ++ K L+F+ + L Y
Sbjct: 1132 ----EARHSENNFQKMVRLIDLIGLFSRYGDLNRINDDWKHSLDFISPECDDAYVILLGY 1187
Query: 1090 VTKCLLTFTNKKLATPLRKIAIKNLVKLASSFPKLFNSPPVLKVLDHEF-EAGVLDTKLT 1148
K L K LR I N+ ++ LF SP +L LD E V + +
Sbjct: 1188 FQKLL-----KDAKGQLRIHIIDNMSRICLRETSLFISPLMLSTLDMIIAENNVNEVSVL 1242
Query: 1149 IIDCLQVFFSSEE------KKVLMKIGANGTISSSSEMRRLISTQNTTESVNDGVCSALV 1202
L++ + E+ +K+ +K G S+ S R ++ + + +GV ++L+
Sbjct: 1243 FKSFLELLAADEDLIFEADQKLSLK-GKQNVQSNKSVDRDMLKGTKDKQWI-EGVSASLM 1300
Query: 1203 TRYLDSIMDLCLLSDIKDAIVAIKFLQLTLNFHYTNPSHAVPTLIALSCSDANSVKTVST 1262
+L I+D C +++ +++ I+ L+ ++ NP T+IAL + + V+
Sbjct: 1301 QHFLPCILDSCFSKNLRYSMLGIEILKCIIHQGLVNPRMCFSTIIALESNAIKETREVAI 1360
Query: 1263 RLLSTIFEQYESMVFNGLAA 1282
L + + ++ES++ +GL A
Sbjct: 1361 LLHTELHRRHESLI-DGLYA 1379
>Hs7661842 [BDL] KOG1020 Sister chromatid cohesion protein SCC2/Nipped-B
Length = 2158
Score = 91.7 bits (226), Expect = 8e-18
Identities = 196/1054 (18%), Positives = 402/1054 (37%), Gaps = 117/1054 (11%)
Query: 384 ERIKDLSL---GILISLFSEYPSQRLFITEELLSHVHDIXXXXXXXXXXXXD----EFEN 436
E + +L L ++ ++FS Y R I EE+ + + + + + E
Sbjct: 886 ENVSELQLCAIKLVTAVFSRYEKHRQLILEEIFTSLARLPTSKRSLRNFRLNSSDMDGEP 945
Query: 437 GYASYFTVALVAMFQSINALPDAELLSDFTSELLENVLSE---NNAASLELKGLIDNVTT 493
Y T ++ + Q + LP +E S+ + + + + N+ ++ + ++
Sbjct: 946 MYIQMVTALVLQLIQCVVHLPSSEKDSNAEEDSNKKIDQDVVITNSYETAMRTAQNFLSI 1005
Query: 494 TLFE-GLITNPFKFKSIVEIYIQDLLTMIGNPKWAYSHHLLEAFLPKLFQIFSPTYQGTG 552
L + G ++ + E ++QDLL+ + P+W + LL L FS
Sbjct: 1006 FLKKCGSKQGEEDYRPLFENFVQDLLSTVNKPEWPAAELLLSLLGRLLVHQFSNKSTEMA 1065
Query: 553 NFEVLAIQLVGQITATLTDVKLRAASEESRDVKRIFN--------LQNEYKECFDWLGSQ 604
V ++ +G + A L + + ++ ++RI +Q K D+L
Sbjct: 1066 -LRVASLDYLGTVAARLRKDAVTSKMDQG-SIERILKQVSGGEDEIQQLQKALLDYLDEN 1123
Query: 605 TKTYFSDRALWNESLFYISE------------MLDQKEID-----------KTDAQVMNF 641
T+T D +L FYI++ M QK+ + +T Q+M+
Sbjct: 1124 TET---DPSLVFSRKFYIAQWFRDTTLETEKAMKSQKDEESSEGTHHAKEIETTGQIMHR 1180
Query: 642 VIRIIAXXXXXXXXXXXXXXXXXXNNGIDGNERVRSLYMKIVSLSPLFNFYEPALRLILS 701
N+ + + + S+ P ++ L IL
Sbjct: 1181 AENRKKFLRSIIKTTPSQFSTLKMNSDTVDYDDACLIVRYLASMRPFAQSFDIYLTQILR 1240
Query: 702 LLDQQKVKLKSGAVKCLTLLVSKDPQMLDTPFVQETIKNRLYDSSASVRDAILDLLE--- 758
+L + + +++ A+KCL+ +V+ DP +L +Q + RL D+S SVR+A ++LL
Sbjct: 1241 VLGENAIAVRTKAMKCLSEVVAVDPSILARLDMQRGVHGRLMDNSTSVREAAVELLGRFV 1300
Query: 759 --QATTYIQFYREINCNFDDDSIAVRKHVMRMNEKILDTSSDLKIKTFVLEKVLRRIEDE 816
+ Q+Y + D I+VRK V+++ I T + K++RR+ DE
Sbjct: 1301 LCRPQLAEQYYDMLIERILDTGISVRKRVIKILRDICIEQPTFPKITEMCVKMIRRVNDE 1360
Query: 817 EDVIVENARKXXXXXXXXXXSASDLSVKLHRFDXXXXXXXXXXXIGYGGKTXXXXXXXXX 876
E I + + +D + GY
Sbjct: 1361 EG-IKKLVNETFQKLWFTPTPHNDKEAMTRKILNITDVVAACRDTGY----------DWF 1409
Query: 877 XXXXNPSIHKNEDT--KSIFDALRNLVNVLIEEI---TENAASADELSESNAR--NRYDL 929
+ ED+ K + A LV+ L+E I E+ A +D ++ R
Sbjct: 1410 EQLLQNLLKSEEDSSYKPVKKACTQLVDNLVEHILKYEESLADSDNKGVNSGRLVACITT 1469
Query: 930 LYFFANCPINFISKPHLYSLFPYLSSNFNGKCYLLLL----KVFRSCIKKHSNIKLKFLH 985
L+ F+ + K H ++ PYL++ + + +++ K+ + + FL
Sbjct: 1470 LFLFSKIRPQLMVK-HAMTMQPYLTTKCSTQNDFMVICNVAKILELVVPLMEHPSETFLA 1528
Query: 986 DLETTLLAKLSKLNTREIEEALAICWETSTKTRKEDKLLKVCAS----CIEQLRPYVTQA 1041
+E L+ + K ++ ++ K + K + C + I +L+ +Q
Sbjct: 1529 TIEEDLMKLIIKYGMTVVQHCVSCLGAVVNKVTQNFKFVWACFNRYYGAISKLK---SQH 1585
Query: 1042 VTAPSSLK-LDGKVQRLIYLCTGFARMCHFKENEKRLEFLRGDE--HLYQYVTKCLLTFT 1098
P++ L K L L T A HF + LE +G+ ++ V + L+ FT
Sbjct: 1586 QEDPNNTSLLTNKPALLRSLFTVGALCRHF---DFDLEDFKGNSKVNIKDKVLELLMYFT 1642
Query: 1099 NKKLATPLRKIAIKNLVKLASSF---PKLFNSPPVLKVLDH--EFEAGVLDTKLTIIDCL 1153
++ K ++ L +F P L V + ++ + ++ K+ ++ L
Sbjct: 1643 KHS----DEEVQTKAIIGLGFAFIQHPSLMFEQEVKNLYNNILSDKNSSVNLKIQVLKNL 1698
Query: 1154 QVFFSSEEKKVLMKIGANGTISSSSEMRRLISTQNTTESVNDGVCSALVTRYLDSIMDLC 1213
Q + E+ ++ ++ +++ + V+ G+ S+++ YL +++
Sbjct: 1699 QTYLQEEDTRMQQADRDWKKVAKQEDLKEM-------GDVSSGMSSSIMQLYLKQVLEAF 1751
Query: 1214 LLSDIKDAIVAIKFLQLTLNFHYTNPSHAVPTLIALSCSDANSVKTVSTRLLSTIFEQYE 1273
+ A+ + LTLN +P VP LIA+ +++ + + L I ++Y
Sbjct: 1752 FHTQSSVRHFALNVIALTLNQGLIHPVQCVPYLIAMGTDPEPAMRNKADQQLVEIDKKYA 1811
Query: 1274 SMVFNGLAAGFKKCCVVFKSLL-----PSELERKDH----CMKRLQCILSNNKKNGKKYV 1324
+ AG K V +++ P R+D L ++ N+++ + ++
Sbjct: 1812 GFIHMKAVAGMKMSYQVQQAINTCLKDPVRGFRQDESSSALCSHLYSMIRGNRQHRRAFL 1871
Query: 1325 SVVKNLTISECYKTHSVSNTELLFLLHNMSQIDY 1358
+ NL T T LL++ N++ Y
Sbjct: 1872 ISLLNLFDD----TAKTDVTMLLYIADNLACFPY 1901
>Hs19718749 [BDL] KOG1020 Sister chromatid cohesion protein SCC2/Nipped-B
Length = 2265
Score = 91.7 bits (226), Expect = 8e-18
Identities = 196/1054 (18%), Positives = 402/1054 (37%), Gaps = 117/1054 (11%)
Query: 384 ERIKDLSL---GILISLFSEYPSQRLFITEELLSHVHDIXXXXXXXXXXXXD----EFEN 436
E + +L L ++ ++FS Y R I EE+ + + + + + E
Sbjct: 886 ENVSELQLCAIKLVTAVFSRYEKHRQLILEEIFTSLARLPTSKRSLRNFRLNSSDMDGEP 945
Query: 437 GYASYFTVALVAMFQSINALPDAELLSDFTSELLENVLSE---NNAASLELKGLIDNVTT 493
Y T ++ + Q + LP +E S+ + + + + N+ ++ + ++
Sbjct: 946 MYIQMVTALVLQLIQCVVHLPSSEKDSNAEEDSNKKIDQDVVITNSYETAMRTAQNFLSI 1005
Query: 494 TLFE-GLITNPFKFKSIVEIYIQDLLTMIGNPKWAYSHHLLEAFLPKLFQIFSPTYQGTG 552
L + G ++ + E ++QDLL+ + P+W + LL L FS
Sbjct: 1006 FLKKCGSKQGEEDYRPLFENFVQDLLSTVNKPEWPAAELLLSLLGRLLVHQFSNKSTEMA 1065
Query: 553 NFEVLAIQLVGQITATLTDVKLRAASEESRDVKRIFN--------LQNEYKECFDWLGSQ 604
V ++ +G + A L + + ++ ++RI +Q K D+L
Sbjct: 1066 -LRVASLDYLGTVAARLRKDAVTSKMDQG-SIERILKQVSGGEDEIQQLQKALLDYLDEN 1123
Query: 605 TKTYFSDRALWNESLFYISE------------MLDQKEID-----------KTDAQVMNF 641
T+T D +L FYI++ M QK+ + +T Q+M+
Sbjct: 1124 TET---DPSLVFSRKFYIAQWFRDTTLETEKAMKSQKDEESSEGTHHAKEIETTGQIMHR 1180
Query: 642 VIRIIAXXXXXXXXXXXXXXXXXXNNGIDGNERVRSLYMKIVSLSPLFNFYEPALRLILS 701
N+ + + + S+ P ++ L IL
Sbjct: 1181 AENRKKFLRSIIKTTPSQFSTLKMNSDTVDYDDACLIVRYLASMRPFAQSFDIYLTQILR 1240
Query: 702 LLDQQKVKLKSGAVKCLTLLVSKDPQMLDTPFVQETIKNRLYDSSASVRDAILDLLE--- 758
+L + + +++ A+KCL+ +V+ DP +L +Q + RL D+S SVR+A ++LL
Sbjct: 1241 VLGENAIAVRTKAMKCLSEVVAVDPSILARLDMQRGVHGRLMDNSTSVREAAVELLGRFV 1300
Query: 759 --QATTYIQFYREINCNFDDDSIAVRKHVMRMNEKILDTSSDLKIKTFVLEKVLRRIEDE 816
+ Q+Y + D I+VRK V+++ I T + K++RR+ DE
Sbjct: 1301 LCRPQLAEQYYDMLIERILDTGISVRKRVIKILRDICIEQPTFPKITEMCVKMIRRVNDE 1360
Query: 817 EDVIVENARKXXXXXXXXXXSASDLSVKLHRFDXXXXXXXXXXXIGYGGKTXXXXXXXXX 876
E I + + +D + GY
Sbjct: 1361 EG-IKKLVNETFQKLWFTPTPHNDKEAMTRKILNITDVVAACRDTGY----------DWF 1409
Query: 877 XXXXNPSIHKNEDT--KSIFDALRNLVNVLIEEI---TENAASADELSESNAR--NRYDL 929
+ ED+ K + A LV+ L+E I E+ A +D ++ R
Sbjct: 1410 EQLLQNLLKSEEDSSYKPVKKACTQLVDNLVEHILKYEESLADSDNKGVNSGRLVACITT 1469
Query: 930 LYFFANCPINFISKPHLYSLFPYLSSNFNGKCYLLLL----KVFRSCIKKHSNIKLKFLH 985
L+ F+ + K H ++ PYL++ + + +++ K+ + + FL
Sbjct: 1470 LFLFSKIRPQLMVK-HAMTMQPYLTTKCSTQNDFMVICNVAKILELVVPLMEHPSETFLA 1528
Query: 986 DLETTLLAKLSKLNTREIEEALAICWETSTKTRKEDKLLKVCAS----CIEQLRPYVTQA 1041
+E L+ + K ++ ++ K + K + C + I +L+ +Q
Sbjct: 1529 TIEEDLMKLIIKYGMTVVQHCVSCLGAVVNKVTQNFKFVWACFNRYYGAISKLK---SQH 1585
Query: 1042 VTAPSSLK-LDGKVQRLIYLCTGFARMCHFKENEKRLEFLRGDE--HLYQYVTKCLLTFT 1098
P++ L K L L T A HF + LE +G+ ++ V + L+ FT
Sbjct: 1586 QEDPNNTSLLTNKPALLRSLFTVGALCRHF---DFDLEDFKGNSKVNIKDKVLELLMYFT 1642
Query: 1099 NKKLATPLRKIAIKNLVKLASSF---PKLFNSPPVLKVLDH--EFEAGVLDTKLTIIDCL 1153
++ K ++ L +F P L V + ++ + ++ K+ ++ L
Sbjct: 1643 KHS----DEEVQTKAIIGLGFAFIQHPSLMFEQEVKNLYNNILSDKNSSVNLKIQVLKNL 1698
Query: 1154 QVFFSSEEKKVLMKIGANGTISSSSEMRRLISTQNTTESVNDGVCSALVTRYLDSIMDLC 1213
Q + E+ ++ ++ +++ + V+ G+ S+++ YL +++
Sbjct: 1699 QTYLQEEDTRMQQADRDWKKVAKQEDLKEM-------GDVSSGMSSSIMQLYLKQVLEAF 1751
Query: 1214 LLSDIKDAIVAIKFLQLTLNFHYTNPSHAVPTLIALSCSDANSVKTVSTRLLSTIFEQYE 1273
+ A+ + LTLN +P VP LIA+ +++ + + L I ++Y
Sbjct: 1752 FHTQSSVRHFALNVIALTLNQGLIHPVQCVPYLIAMGTDPEPAMRNKADQQLVEIDKKYA 1811
Query: 1274 SMVFNGLAAGFKKCCVVFKSLL-----PSELERKDH----CMKRLQCILSNNKKNGKKYV 1324
+ AG K V +++ P R+D L ++ N+++ + ++
Sbjct: 1812 GFIHMKAVAGMKMSYQVQQAINTCLKDPVRGFRQDESSSALCSHLYSMIRGNRQHRRAFL 1871
Query: 1325 SVVKNLTISECYKTHSVSNTELLFLLHNMSQIDY 1358
+ NL T T LL++ N++ Y
Sbjct: 1872 ISLLNLFDD----TAKTDVTMLLYIADNLACFPY 1901
>7289131 [BDL] KOG1020 Sister chromatid cohesion protein SCC2/Nipped-B
Length = 2053
Score = 70.5 bits (171), Expect = 2e-11
Identities = 127/638 (19%), Positives = 237/638 (36%), Gaps = 51/638 (7%)
Query: 687 PLFNFYEPALRLILSLLDQQKVKLKSGAVKCLTLLVSKDPQMLDTPFVQETIKNRLYDSS 746
P ++ L+ I+ ++++ + +++ A+KCL +V DP +L +Q + + D++
Sbjct: 1098 PFSQSFDGCLKKIILVVNEPSIAVRTRAMKCLANIVEVDPLVLKRKDMQMGVNQKFLDTA 1157
Query: 747 ASVRDAILDL-----LEQATTYIQFYREINCNFDDDSIAVRKHVMRMNEKILDTSSDLKI 801
SVR+A +DL L Q+Y ++ D ++VRK V+++ I D
Sbjct: 1158 ISVREAAVDLVGKFVLSNQDLIDQYYDMLSTRILDTGVSVRKRVIKILRDICLEYPDFSK 1217
Query: 802 KTFVLEKVLRRIEDEEDV--IVENARKXXXXXXXXXXSASDLSVKLHRFDXXXXXXXXXX 859
+ K++RR+ DEE + +V + K++
Sbjct: 1218 IPEICVKMIRRVHDEEGIQKLVTEVFMKMWFTPCTKNDKIGIQRKINHIIDVVNTAHDTG 1277
Query: 860 XIGYGGKTXXXXXXXXXXXXXNPSIHK-----NEDTKSIFDALRNLVNVLIEEITENAAS 914
G + + +E I A + L + L++ + E
Sbjct: 1278 TTWLEGLLMSIFKPRDNMLRSEGCVQEFIKKNSEPPMDIVIACQQLADGLVDRLIE---- 1333
Query: 915 ADELSESNARNRYDLLYFFANCPINFISKPHLYSLFPYLS----SNFNGKCYLLLLKVFR 970
++ S L+ A + K H ++ PYL+ S K + +
Sbjct: 1334 LEDTDNSRMLGCITTLHLLAKVRPQLLVK-HAITIEPYLNIKCHSATAAKFICAVADILE 1392
Query: 971 SCIKKHSNIKLKFLHDLETTLLAKLSKLNTREIEEALAICWETSTKTRKEDKLLKVCAS- 1029
+ +N FL LE L+ + N E+ ++ K KL++ C
Sbjct: 1393 KVVPLVNNASESFLASLEEHLMLLVVSRNQAEVTSCVSCLGALVNKITHNFKLIRDCFQK 1452
Query: 1030 ---CIEQLRPYVTQAVTAPSSLKLDGKVQRLIYLCTGFARMCHFKENEKRLEFLRG-DEH 1085
++ R V Q + ++ +R ++ R FK E G
Sbjct: 1453 FYRVLDVSRSQVIQGNNSVDNI-YTPSFRRSLFTIGILMRYFDFKSPIALGETNDGLPVS 1511
Query: 1086 LYQYVTKCLLTF---TNKKLATPLRKIAIKNLVKLASSFPKL---FNSPPVLKVLDHEFE 1139
+ + V CL+ F TN++ +RK A+ +L SF L + + LK L E
Sbjct: 1512 ICEDVFHCLMFFCRCTNQE----IRKQALISL----GSFCVLNDGYLTRSELKNLYCEIL 1563
Query: 1140 AGVL-DTKLTIIDCLQVFFSSEEKKVLMKIGANGTISSSSEMRRLISTQNTTE--SVNDG 1196
+ + D II ++ E ++ M + E + ++ E V+ G
Sbjct: 1564 SSIANDAGFKIICMRNIWIYLTESEMFMH-------NKEKEWEKQSKHEDLKEMNDVSSG 1616
Query: 1197 VCSALVTRYLDSIMDLCLLSDIKDAIVAIKFLQLTLNFHYTNPSHAVPTLIALSCSDANS 1256
+ S ++ YL+ I++ L D + A+K +Q+ L +P VP LI LS
Sbjct: 1617 MASRIIQLYLEEILECFLNRDDTVRLWAVKVIQIVLRQGLVHPVRMVPYLICLSTDHRIE 1676
Query: 1257 VKTVSTRLLSTIFEQYESMVFNGLAAGFKKCCVVFKSL 1294
+ LL I + Y V + G + C + K L
Sbjct: 1677 SAHRADALLKDIDKTYSGFVNMKVQFGLQLCFKLQKIL 1714
>CE27255 [BDL] KOG1020 Sister chromatid cohesion protein SCC2/Nipped-B
Length = 2227
Score = 63.5 bits (153), Expect = 2e-09
Identities = 36/117 (30%), Positives = 66/117 (55%), Gaps = 5/117 (4%)
Query: 708 VKLKSGAVKCLTLLVSKDPQMLDTPFVQETIKNRLYDSSASVRDAILDLLEQATTYIQ-- 765
V L+S A+KCL+ ++ D +L VQ+ + R+ DS A VR++ ++L+ + Y +
Sbjct: 1323 VALRSKALKCLSSIIEADSSVLILEDVQQAVHTRMVDSHAQVRESAVELIGRFVLYDEEY 1382
Query: 766 ---FYREINCNFDDDSIAVRKHVMRMNEKILDTSSDLKIKTFVLEKVLRRIEDEEDV 819
+Y +I D +AVRK V+R+ +I + ++ +L +++RR+ DEE V
Sbjct: 1383 VRKYYSQIAERILDTGVAVRKRVIRIMREICEKFPTFEMIPDMLARMIRRVTDEEGV 1439
>At5g15540 [BDL] KOG1020 Sister chromatid cohesion protein SCC2/Nipped-B
Length = 1755
Score = 56.2 bits (134), Expect = 4e-07
Identities = 30/134 (22%), Positives = 71/134 (52%), Gaps = 5/134 (3%)
Query: 692 YEPALRLILSLLDQQKVKLKSGAVKCLTLLVSKDPQMLDTPFVQETIKNRLYDSSASVRD 751
++ L ++L+ L + +++ A++ ++++V DP++L VQ ++ R DS+ SVR+
Sbjct: 774 FDKILNMLLASLRENAPNIRAKALRAVSIIVEADPEVLCDKRVQLAVEGRFCDSAISVRE 833
Query: 752 AILDLL-----EQATTYIQFYREINCNFDDDSIAVRKHVMRMNEKILDTSSDLKIKTFVL 806
A L+L+ I+++ ++ D ++VRK +++ + ++ + T
Sbjct: 834 AALELVGRHIASHPDVGIKYFEKVAERIKDTGVSVRKRAIKIIRDMCTSNPNFSEFTSAC 893
Query: 807 EKVLRRIEDEEDVI 820
++L RI D+E +
Sbjct: 894 AEILSRISDDESSV 907
Database: KOG eukaryal database 04/03
Posted date: Apr 14, 2003 1:07 PM
Number of letters in database: 30,389,216
Number of sequences in database: 60,738
Lambda K H
0.319 0.135 0.381
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 80,360,469
Number of Sequences: 60738
Number of extensions: 3322280
Number of successful extensions: 9718
Number of sequences better than 1.0e-05: 7
Number of HSP's better than 0.0 without gapping: 1
Number of HSP's successfully gapped in prelim test: 6
Number of HSP's that attempted gapping in prelim test: 9677
Number of HSP's gapped (non-prelim): 33
length of query: 1480
length of database: 30,389,216
effective HSP length: 119
effective length of query: 1361
effective length of database: 23,161,394
effective search space: 31522657234
effective search space used: 31522657234
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)