ORF STATUS Function Best COG Functional category Pathways and functional systems
r_klactIV4519 good L KOG3662 Replication, recombination and repair Cell division control protein/predicted DNA repair exonuclease
Only best alignment is shown:
BLASTP 2.2.3 [May-13-2002]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= r_klactIV4519 1539699 1541132 478
(478 letters)
Database: KOG eukaryal database 04/03
60,738 sequences; 30,389,216 total letters
Searching..................................................done
Color Key for Alignment Scores: 
Score E
Sequences producing significant alignments: (bits) Value
YDR182w [L] KOG3662 Cell division control protein/predicted DNA ... 516 e-146
SPAC630.12 [L] KOG3662 Cell division control protein/predicted D... 253 6e-67
At1g53710 [L] KOG3662 Cell division control protein/predicted DN... 106 9e-23
Hs20070434 [L] KOG3662 Cell division control protein/predicted D... 82 2e-15
CE28878 [L] KOG3662 Cell division control protein/predicted DNA ... 64 5e-10
7297355 [L] KOG3662 Cell division control protein/predicted DNA ... 59 1e-08
CE03828 [L] KOG3662 Cell division control protein/predicted DNA ... 55 2e-07
SPAC23A1.02c [L] KOG3662 Cell division control protein/predicted... 52 2e-06
>YDR182w [L] KOG3662 Cell division control protein/predicted DNA repair
exonuclease
Length = 491
Score = 516 bits (1330), Expect = e-146
Identities = 254/468 (54%), Positives = 322/468 (68%), Gaps = 13/468 (2%)
Query: 3 SRRAENRRSLPEDISVQEKPKGFKIRRSSFTQKLHIYWRYIFVLLIGWLLLIQYYERTVV 62
S+ + S D K + K +S ++L IYWRYI ++ I WL LI YYE VV
Sbjct: 7 SKSVLSTHSKKSDDKAHYKSRSKKKSKSRSKKRLRIYWRYISIVWILWLGLISYYESVVV 66
Query: 63 KRAMKKCDWDQWEEWDSKVVAHRVGLYADPQIMDLYSYPSRPTIVNWFTRQILDNYHARN 122
KRAMKKC W WE+W +HRVGL+ADPQIMD YSYP RP IVN+FTR I+D+YH RN
Sbjct: 67 KRAMKKCQWSTWEDWPEGAESHRVGLFADPQIMDEYSYPGRPQIVNYFTRVIVDHYHRRN 126
Query: 123 WKFFHYYMKPDSVFFLGDLFDGGRNWEVNEWITEYKRFNSIFPKKPGHLTVMSLPGNHDI 182
WK+ YY+ PDS FFLGDLFDGGRNW+ +WI EY RFN IFPKKP TVMSLPGNHDI
Sbjct: 127 WKYVQYYLDPDSNFFLGDLFDGGRNWDDKQWIKEYTRFNQIFPKKPLRRTVMSLPGNHDI 186
Query: 183 GFGDTIIESSLERFTTFFGDPSSQWTVGNHTFVLLDTISLSDRQNENISAVPRDFMHKFE 242
GFGDT++ESSL+RF+++FG+ SS GNHTFVLLDTISLSD+ N N+S VPR F+ F
Sbjct: 187 GFGDTVVESSLQRFSSYFGETSSSLDAGNHTFVLLDTISLSDKTNPNVSRVPRQFLDNFA 246
Query: 243 MSSPKYPRILLTHVPLFRNPIEQPCGKMREAQKPFPLMKGHQYQTVIDEDLSKEVLSAIQ 302
M S PRILLTHVPL+R+P +Q CG++RE+++PFP+ KGHQYQTVI+ D+S+E+L+ IQ
Sbjct: 247 MGSHPLPRILLTHVPLWRDPEQQTCGQLRESKEPFPIQKGHQYQTVIENDISQEILTKIQ 306
Query: 303 PKIVFSGDDHDYCHVNHSYFANNLPKMAEEITVKSCAMNMGISKPAIQLISLYNPEN--- 359
P+I+FSGDDHD+C ++HSY K A+EITVKSCAMNMGIS+PAIQL+SLYNP +
Sbjct: 307 PEILFSGDDHDHCQISHSYPFQGKTKNAQEITVKSCAMNMGISRPAIQLLSLYNPSDLTM 366
Query: 360 -----DDTKTTYKTNICYFPNPYKPIISYCVALSISAVLLFWMTLLPLSFNE---TVVKR 411
+ TY+T +CY P+PYK I Y L SA + +M P SFN T++ R
Sbjct: 367 VNAGGEYASKTYQTELCYMPDPYKAIRMYLWGLLFSAAFIAYMHFFPKSFNNRVATIMNR 426
Query: 412 LPFRNADLGSILPIAAKENNAISINAINFKAANWRVEKERSFVNFLLN 459
+ R S LP+ + + S ++ + + V RS FL+N
Sbjct: 427 VFTRPDGNTSDLPLPTSISKSKSKKSLTH--SKYAVNDTRSIKQFLVN 472
>SPAC630.12 [L] KOG3662 Cell division control protein/predicted DNA repair
exonuclease
Length = 422
Score = 253 bits (645), Expect = 6e-67
Identities = 142/366 (38%), Positives = 203/366 (54%), Gaps = 17/366 (4%)
Query: 44 FVLLIGWLLLIQYYERTVVKRAMKKCDWDQWEEWDSKVVAHRVGLYADPQIMD--LYSYP 101
F+++I + + Y E+ + R KKCDW WE+W+S R+ L ADPQ++D Y YP
Sbjct: 6 FLVIIAFCFYVLYLEKIIHTRPHKKCDWRSWEQWESTGNPVRIALVADPQLVDDLTYDYP 65
Query: 102 SRPTI--VNWFTRQILDNYHARNWKFFHYYMKPDSVFFLGDLFDGGRNWEVNEWITEYKR 159
RP I V W + Q L R+W++ H +KPD F +GDL D GR + E+ +Y R
Sbjct: 66 -RPLIGIVKWISDQFL----RRHWRYLHKSLKPDITFIMGDLMDTGREFATEEFKKDYFR 120
Query: 160 F-NSIFPKKPGHLTVMSLPGNHDIGFGDTIIESSLERFTTFFGDPSSQWTVGNHTFVLLD 218
N + PK L + PGNHDIGFG+ I ++RF + FG S VGNHT V++D
Sbjct: 121 MMNVLDPKFTNKLEIY--PGNHDIGFGNHAIVKDIQRFESLFGPTSRSIDVGNHTLVIVD 178
Query: 219 TISLSDRQNENISAVPRDFMHKFEMSSPKY-PRILLTHVPLFRNPIEQPCGKMREAQKPF 277
I LS+ N + RDF+ FE + PRILL+HVPLFR P CG++RE
Sbjct: 179 GIRLSNNVNPQVYQPARDFLKSFETNKDNSRPRILLSHVPLFR-PAINSCGELREKDDVI 237
Query: 278 PLMKGHQYQTVIDEDLSKEVLSAIQPKIVFSGDDHDYCHVNHSYFANNLPKMAEEITVKS 337
G+QYQ ++ +LS+ +L A++P F+GDDHDYC V H+Y + E VK+
Sbjct: 238 KYGLGYQYQNLLLPELSESILKAVEPIAAFAGDDHDYCEVVHNYQVDTREAATTEYNVKA 297
Query: 338 CAMNMGISKPAIQLISL---YNPENDDTKTTYKTNICYFPNPYKPIISYCVALSISAVLL 394
+M GI P QL+SL Y+ D K++Y+T +C PN + + Y ++SI L+
Sbjct: 298 FSMTSGILYPGYQLLSLNYPYDNPKADQKSSYQTKLCILPNQIQIYVWYGASISIFFALI 357
Query: 395 FWMTLL 400
T +
Sbjct: 358 LLRTAI 363
>At1g53710 [L] KOG3662 Cell division control protein/predicted DNA repair
exonuclease
Length = 393
Score = 106 bits (264), Expect = 9e-23
Identities = 73/254 (28%), Positives = 114/254 (44%), Gaps = 38/254 (14%)
Query: 85 RVGLYADPQIMDLYSYPSRPTIVNWFTRQILDNYHARNWKFFHYYM--KPDSVFFLGDLF 142
+V + DPQ+MD S+ + Q + + R FF + KPD V FLGD F
Sbjct: 53 KVAIVTDPQLMDKTSFRLSSKTLALELAQFYTDINMRR-SFFRSVLPFKPDVVLFLGDYF 111
Query: 143 DGGRNWEVNEWITEYKRFNSIF----PKKPGHLTVMSLPGNHDIGFGDTIIESSLERFTT 198
DGG EW R +F + G + +PGNHDIG+ I +R+
Sbjct: 112 DGGPFLSEEEWQESLNRLKHVFGLNSEGRVGDIPTFYIPGNHDIGYSRVI-----DRYEK 166
Query: 199 FFGDPSSQWTVGNHTFVLLDTISLSDRQNENISAVPRDFMHKFEMSSPKYPRILLTHVPL 258
FG + ++ +GN F+ +D ++ +++++ F+ + +PR+LLTH+PL
Sbjct: 167 VFGVRNRRFMIGNVEFISIDAQAIDGNSKKDLASEVWKFVQNVSTDAQSHPRVLLTHIPL 226
Query: 259 FRNPIEQPCGKMREAQKPFPLMKGHQYQTVIDEDLSKEVLSAIQPKIVFSGDDHDYCHVN 318
+R P + PCG H+ +VID+ L V SG DHD C V
Sbjct: 227 YR-PDQTPCGP-------------HRGSSVIDQIL------------VLSGHDHDQCTVI 260
Query: 319 HSYFANNLPKMAEE 332
H A ++ + E
Sbjct: 261 HKSKAGSVTEEKNE 274
>Hs20070434 [L] KOG3662 Cell division control protein/predicted DNA repair
exonuclease
Length = 396
Score = 81.6 bits (200), Expect = 2e-15
Identities = 77/292 (26%), Positives = 123/292 (41%), Gaps = 53/292 (18%)
Query: 128 YYMKPDSVFFLGDLFDGGRNWEVNE-WITEYKRFNSIFPKKPGHLTVMSLPGNHDIGFGD 186
+ ++P+ VF LGD+FD G+ W E W + +RF +F + P H+ + + GNHDIGF
Sbjct: 107 WLLQPEVVFILGDIFDEGK-WSTPEAWADDVERFQKMF-RHPSHVQLKVVAGNHDIGFHY 164
Query: 187 TIIESSLERF-TTFFGDPSSQWTVGNHTFVLLDTISL--------SDRQNENISAVPRDF 237
+ +ERF F + W N FV++++++L S+ + E I R
Sbjct: 165 EMNTYKVERFEKVFSSERLFSWKGIN--FVMVNSVALNGDGCGICSETEAELIEVSHRLN 222
Query: 238 MHKFEMSS---------PKYPRILLTHVPLFR----NPIEQPCGKMREAQKPFPLMKGHQ 284
+ S P +LL H PL+R N + E PF +
Sbjct: 223 CSREARGSSRCGPGPLLPTSAPVLLQHYPLYRRSDANCSGEDAAPAEERDIPF-----KE 277
Query: 285 YQTVIDEDLSKEVLSAIQPKIVFSGDDHDYCHVNHSYFANNLPKMAEEITVKSCAMNMGI 344
V+ + S+++L +QP++V SG H C V+H +P+ +
Sbjct: 278 NYDVLSREASQKLLWWLQPRLVLSGHTHSACEVHH---GGRVPE---------------L 319
Query: 345 SKPAIQLISLYNPE---NDDTKTTYKTNICYFPNPYKPIISYCVALSISAVL 393
S P+ + NP T T Y + CY P +I YC + VL
Sbjct: 320 SVPSFSWRNRNNPSFIMGSITPTDYTLSKCYLPREDVVLIIYCGEVGFLVVL 371
>CE28878 [L] KOG3662 Cell division control protein/predicted DNA repair
exonuclease
Length = 493
Score = 63.9 bits (154), Expect = 5e-10
Identities = 64/261 (24%), Positives = 112/261 (42%), Gaps = 39/261 (14%)
Query: 121 RNWKFFHYYM------KPDSVFFLGDLFDGGRNWEVNEWITEY-KRFNSIFPKKPGHLTV 173
R W+ + + PD FFLGDL D G+ W Y +RF +F V
Sbjct: 71 REWQMYQSFWISTWIHSPDVTFFLGDLMDEGK-WAGRPVFEAYAERFKKLFGDNE---KV 126
Query: 174 MSLPGNHDIGFGDTIIES--------------------SLERF-TTFFGDPSSQWTVGNH 212
++L GNHD+GF ++++ +LE F F + + H
Sbjct: 127 ITLAGNHDLGFHYALVQTFATHLTPTVELKNYLLIMPETLEMFKKEFRRGLIDEMKIKKH 186
Query: 213 TFVLLDTISLSDRQNENISAVPRDFMHKFEMSSPKYPRILLTHVPLFRNPIEQPCGKMRE 272
FVL++++++ + + K + +PK I+L H PL+R + C ++ E
Sbjct: 187 RFVLINSMAMHG-DGCRLCHEAELILEKIKSRNPKNRPIVLQHFPLYRKS-DAECDQVDE 244
Query: 273 AQKPFPLMKGHQYQ-TVIDEDLSKEVLSAIQPKIVFSGDDHDYCHVNHSYFANNLPKMAE 331
Q L + ++ Q + ++ S +++ ++ PK VF G H C + N+ +
Sbjct: 245 -QHEIDLKEMYREQWDTLSKESSLQIIDSLNPKAVFGGHTHKMCKKKWNKTGNS--EYFY 301
Query: 332 EITVKSCAMNMGISKPAIQLI 352
E TV S + G PA+ L+
Sbjct: 302 EYTVNSFSWRNG-DVPAMLLV 321
>7297355 [L] KOG3662 Cell division control protein/predicted DNA repair
exonuclease
Length = 257
Score = 59.3 bits (142), Expect = 1e-08
Identities = 45/183 (24%), Positives = 88/183 (47%), Gaps = 12/183 (6%)
Query: 44 FVLLIGWLLLIQYYERTVVKRAMKKCDWDQWEEWDSKVVAHRVGLYADPQIMDLYSYPSR 103
FV+++ L+ +Y VV ++KC W + + R + ADP ++
Sbjct: 8 FVIVLCALIFCEYVADFVV---LQKCKWPEIKRKKYVDDPLRAMILADPHLLG------- 57
Query: 104 PTIVNWFTRQILDNYHARNWKFFHYYMKPDSVFFLGDLFDGGRNWEVNEWITEYKRFNSI 163
P +W + + + R ++ +PD VF LGDLFD G ++ R+ +
Sbjct: 58 PHRGHWLDKLYREWHMTRAFQAASRLFQPDVVFVLGDLFDEGDMVSDKQFQEYVWRYLKM 117
Query: 164 FPKKPGHLTVMSLPGNHDIGFGDTIIESSLERFTTFFGDPS-SQWTVGNHTFVLLDTISL 222
F PG + ++S+ GNHD+GF + + RF ++ + S + +T+ FV+++++++
Sbjct: 118 FHLPPG-IPLISVAGNHDVGFHYKMHPFFMSRFESYLNNSSVNLYTIKQIHFVVINSMAM 176
Query: 223 SDR 225
R
Sbjct: 177 EGR 179
>CE03828 [L] KOG3662 Cell division control protein/predicted DNA repair
exonuclease
Length = 248
Score = 55.1 bits (131), Expect = 2e-07
Identities = 64/265 (24%), Positives = 106/265 (39%), Gaps = 37/265 (13%)
Query: 137 FLGDLFDGGRNWEVNEWITEYKRFNSIFPKKPGHLTVMSLPGNHDI-GFGDTIIESSLER 195
FLGDLFD G +EW Y+RF I+P G + + G++DI G + I ES +
Sbjct: 2 FLGDLFDEGIESNDDEWYETYERFIGIYPIDRGD-NAIYIAGDNDIGGESELISESRRNQ 60
Query: 196 FTTFFGDPSSQWTVGNHTFVLLDTISLSDRQNENISAVPRDFMHKFEMSSPKYPRILLTH 255
F +F N+ L D S+S+ + + +I+LTH
Sbjct: 61 FYNYF---------RNNVSDLKDRYSISETY-----LFENPILKHITKAQVPVAKIMLTH 106
Query: 256 VPLFRNPIEQPCGKMREAQKPFPLMKGHQYQTVIDEDLSKEVLSAIQPKIVFSGDDHDYC 315
VP + + QK ++ H + T I E P+ V D
Sbjct: 107 VPY----LVEGYKHSDVGQKMDLILSAHDHTTGIYE------YQRSAPRAVLFTRVSD-- 154
Query: 316 HVNHSYFAN---NLPKMAEEITVKSCAMNMGISKPAIQLISLYNPENDDTKTTYKTNICY 372
V+ +YF N N P + E+ +C+ MG+ +S+ +D + ++ +
Sbjct: 155 -VSPTYFKNIGQNEPLI--ELQTPTCSYRMGVYSMGYGALSICRLNDDYRSVQVQYSVLW 211
Query: 373 FPNPYKPIISYCVALSISAVLLFWM 397
P+ + + Y +L SA FW+
Sbjct: 212 LPSRFAQLFLYIFSLIFSA---FWI 233
>SPAC23A1.02c [L] KOG3662 Cell division control protein/predicted DNA repair
exonuclease
Length = 430
Score = 52.0 bits (123), Expect = 2e-06
Identities = 69/278 (24%), Positives = 113/278 (39%), Gaps = 50/278 (17%)
Query: 128 YYMKPDSVFFLGDL--FDGGRNWEVNEW------ITEYKRF----NSIFPKKP---GHLT 172
++ +PD++ LGDL F N E N+ IT K F NS P + G++
Sbjct: 95 FWGQPDAMILLGDLVSFQHLDNEEFNKRAKRLKKITGAKNFWQVGNSSLPARTFENGNIP 154
Query: 173 VMSLPGNHDIGFGDTIIESSLERFTTFFGDPS--SQWTVGNHTFVLLDTISLSDRQNENI 230
V ++ GNHDIG+G ++ + ++ G + S + V ++ SLS +
Sbjct: 155 VWTIAGNHDIGYGCESSDAQISKWEQAMGPVNWVSHFNVSKFPVRVIGINSLSLDDVQFY 214
Query: 231 SAVPRDFMHKFEMSS-----------------------PKYPRILLTHVPLFRNPIEQPC 267
A P D ++ SS P P IL THVPL++ P
Sbjct: 215 DANPSDIINSKSFSSLGILALSKEARDAWQFLFDIALEPSIPTILFTHVPLYK-PANVCV 273
Query: 268 GKMREAQKPFPLMKGHQYQTVIDEDLSKEVLSAIQPKIVFSGDDHDYCHVNHSYFANNLP 327
+ R ++ +K + + E++ +I K+V SG DH C H P
Sbjct: 274 DEPRIVRQLDFRVKSQNHLSYNTTMKIFELIPSI--KLVLSGHDHMGCDYEH-------P 324
Query: 328 KMAEEITVKSCAMNMGISKPAIQLISLYNPENDDTKTT 365
A E T+ S G + ++LI+ + + +K T
Sbjct: 325 NGAIEHTLPSAMGYFGGNIGFVKLIATNDVLTESSKNT 362
Database: KOG eukaryal database 04/03
Posted date: Apr 14, 2003 1:07 PM
Number of letters in database: 30,389,216
Number of sequences in database: 60,738
Lambda K H
0.323 0.138 0.435
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 30,392,568
Number of Sequences: 60738
Number of extensions: 1370389
Number of successful extensions: 2726
Number of sequences better than 1.0e-05: 8
Number of HSP's better than 0.0 without gapping: 2
Number of HSP's successfully gapped in prelim test: 6
Number of HSP's that attempted gapping in prelim test: 2703
Number of HSP's gapped (non-prelim): 8
length of query: 478
length of database: 30,389,216
effective HSP length: 110
effective length of query: 368
effective length of database: 23,708,036
effective search space: 8724557248
effective search space used: 8724557248
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.9 bits)