ORF STATUS Function Best COG Functional category Pathways and functional systems
r_klactIV4527 good U KOG3745 Intracellular trafficking, secretion, and vesicular transport Exocyst subunit - Sec10p
Only best alignment is shown:
BLASTP 2.2.3 [May-13-2002]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= r_klactIV4527 1543607 1541157 -817
(817 letters)
Database: KOG eukaryal database 04/03
60,738 sequences; 30,389,216 total letters
Searching..................................................done
Color Key for Alignment Scores: 
Score E
Sequences producing significant alignments: (bits) Value
YLR166c [U] KOG3745 Exocyst subunit - Sec10p 588 e-168
SPAC13F5.06c [U] KOG3745 Exocyst subunit - Sec10p 114 5e-25
Hs5730037 [U] KOG3745 Exocyst subunit - Sec10p 94 6e-19
CE04152 [U] KOG3745 Exocyst subunit - Sec10p 76 2e-13
>YLR166c [U] KOG3745 Exocyst subunit - Sec10p
Length = 871
Score = 588 bits (1517), Expect = e-168
Identities = 339/873 (38%), Positives = 509/873 (57%), Gaps = 59/873 (6%)
Query: 1 MNAIYELDVKWKKILTSDNFLSGLTVNEFVTELSKDQ-------ASKQNAPA------AV 47
MN++YELD KWKK+L +DNFL GLTVNEFV ELSKD A+ +N P A+
Sbjct: 1 MNSLYELDPKWKKLLKTDNFLGGLTVNEFVQELSKDHRNDVLIDANTKNLPTNEKDQDAI 60
Query: 48 NASIPENKQLDAKPFIRTFESVXXXXXXXXXXXXSRSGQLTQQVSQMEISHAKSIMVSRG 107
+I KQLD KP+IRTFES ++ ++QV+ E+ H+++++
Sbjct: 61 REAIW--KQLDPKPYIRTFESTLKELKNLNEETLNKRQYFSEQVATQEVIHSENVIKLSK 118
Query: 108 QLKDIVQNYDQLDHKLSAVTQVVSPLGTKLEKSIKQKNAYIKSVELISFYASFLEEGDCP 167
L + +D+LD +L+ VTQVVSPLG KLE +IK+K YI+SVELI Y F G
Sbjct: 119 DLHTTLLTFDKLDDRLTNVTQVVSPLGDKLETAIKKKQNYIQSVELIRRYNDFYSMGKSD 178
Query: 168 ELNKLLESSDKRDICQGAXXXXXXXXXXXXXXXXXVPKTQEVTQIIEQLATDFEVRILQG 227
+ +L S + + + +PKT +IE+ + E +L+
Sbjct: 179 IVEQLRLSKNWKLNLKSVKLMKNLLILSSKLETSSIPKTINTKLVIEKYSEMMENELLEN 238
Query: 228 FNAAYRENDYSRLHQLAWILDTFNNGVNIIKNFTDKHQFFEESSNFSAK---ESALFTDD 284
FN+AYREN++++L+++A IL+ FN GVN+I++F ++H +F ++ + E+ +
Sbjct: 239 FNSAYRENNFTKLNEIAIILNNFNGGVNVIQSFINQHDYFIDTKQIDLENEFENVFIKNV 298
Query: 285 VFKAELMNPDSHILKYDEKVVEYIQSVFNAIENESKVVATVFENKAPNVMHLFIEKVFEL 344
FK +L++ ++H + + + I V I+NESK+V VFE KA +V+ LFI++VF
Sbjct: 299 KFKEQLIDFENHSVIIETSMQNLINDVETVIKNESKIVKRVFEEKATHVIQLFIQRVFAQ 358
Query: 345 KLRPXXXXXXXXXXXXXXXXXXXXXQSYFSITNNSVKQLAEFLSNLKMDSDGKV-SACLE 403
K+ P F++ K L ++ L++D ++ S LE
Sbjct: 359 KIEPRFEVLLRNSLSISNLAYVRILHGLFTLFGKFTKSLIDYFQLLEIDDSNQILSTTLE 418
Query: 404 KCWKNLFIDILFDRSKYFEVEKRTLENVLVQKASDFNISFDSDIRPRSLANKLNE----- 458
+C+ +LF L+DRSKYF +EKR+LE +LV S F +++D +I R L +K E
Sbjct: 419 QCFADLFSHYLYDRSKYFGIEKRSLEAILVDMTSKFTVNYDKEINKRVLLDKYKEKLSTN 478
Query: 459 VTDFKSSPELKILT---SRSGGRFSQLNLFLKNKFEK-------------RFEHENPA-- 500
V F SP + S S + SQ N FLK +K F + + +
Sbjct: 479 VDAFMHSPRGNTHSRQDSTSRSKLSQFNSFLKTHLDKDHLSLNRTNTLSDSFNNSSSSTQ 538
Query: 501 -----------QLNITSKKIDRD-----YFTLSYIDLMIKCSVESLARVTELVPAIADDF 544
+ T+ ID ++L+ +D M+KC VES ARV EL+P A +
Sbjct: 539 YDVANNSSSLVNSSFTASDIDNSPNSPANYSLNDVDSMLKCVVESTARVMELIPNKAHLY 598
Query: 545 TYELVETSLIGVIDSYIESALEVAHAQLNSIDIHRETS-IELKFLKYISTATEMISIVSA 603
E+++ +G++DSY+E ALEVA+ ++ +DI++ + L FLK+IS +TE++ ++S
Sbjct: 599 ILEILKIMFLGIVDSYMEIALEVAYWKICKVDINKTAGVVNLNFLKFISMSTEILDLLSI 658
Query: 604 YIKSIVLPLLQNCPSIKRKVIALSNAYFKKCELLMNLLIVETSKLLNQKFTLILSKQKRK 663
IKSI LPLL N P IK ++I ++N+ +K E+L+N+++ ET +++ KF+ IL KQK+K
Sbjct: 659 SIKSIFLPLLNNSPEIKAQIIEMTNSQIQKMEILINIILQETITVISTKFSAILCKQKKK 718
Query: 664 DFLSKSQDFLDQDTETTTELVNVLSSVYSQSALYLKNGNLKAFLTKLGDNLFEQLLNHYK 723
DF+ KSQ+ LDQDT E+VN+L+ ++ QS+ +LK NL+ FLT +G+ L+ LL+HY
Sbjct: 719 DFVPKSQELLDQDTLPAIEIVNILNLIFEQSSKFLKGKNLQTFLTLIGEELYGLLLSHYS 778
Query: 724 KFQVSSTGGVIVTKDIIAFQTAVEDWDVEELNEKFATLRELSNLFTVQPELLTSLTKEGR 783
FQV+S GGV+VTKDII +QTA+EDW V L +KFATLREL+NLFTVQPELL SLTKEG
Sbjct: 779 HFQVNSIGGVVVTKDIIGYQTAIEDWGVASLIDKFATLRELANLFTVQPELLESLTKEGH 838
Query: 784 LVNVDREIIDEYISKREDYNQDGFIGKFKASLR 816
L ++ R+II YIS RED+N D FI K + R
Sbjct: 839 LADIGRDIIQSYISNREDFNHDNFINSVKLNFR 871
>SPAC13F5.06c [U] KOG3745 Exocyst subunit - Sec10p
Length = 811
Score = 114 bits (286), Expect = 5e-25
Identities = 156/815 (19%), Positives = 321/815 (39%), Gaps = 63/815 (7%)
Query: 13 KILTSDNFLSGLTVNEFVTELSKDQASKQNAPAAVNASIPENKQLDAKPFIRTFESVXXX 72
K+L S N G+ EFV + ++ QN + +SI + I++F +
Sbjct: 13 KLLNSLNDNKGIPSTEFVEKFAESLYETQNDGSKKLSSIDGS--------IKSFAACLHE 64
Query: 73 XXXXXXXXXSRSGQLTQQVSQMEISHAKSIMVSRGQLKDIVQNYDQLDHKLSAVTQVVSP 132
R Q++ + + R + +++ L+ ++ + +
Sbjct: 65 LNRLKSRVGDRIRDYASASKQVQNEYHQKSNHLREKFAQVLELSRHLEDNVNDMRSGLVD 124
Query: 133 LGTKLEKSIKQKNAYIKSVELISFYASFLEEGDCPELNKLLESS--DKRDICQGAXXXXX 190
G +LE++ + + S EL+ +Y F G L ++ DK +C
Sbjct: 125 AGQELERAENNRKRILSSAELLRYYLEF-RSGKPQTLMDFFRTNNHDKMLLC-----AQR 178
Query: 191 XXXXXXXXXXXXVPKTQEVTQIIEQLATDFEVRILQGFNAAYRENDYSRLHQLAWILDTF 250
+P + E IE+ + E L+ FN YR+ ++ + IL F
Sbjct: 179 TRQLLALANEVDLPDSSETLARIEKFSEFLETNFLKFFNNEYRKPNWKGMASFGTILQEF 238
Query: 251 NNGVNIIKNFTDKHQFFEESSNFSAKESALFTDDVFKAELMNPDSHILKYDEKVVEYIQS 310
N G ++++ F ++H+FF + +++ D L +P I + +
Sbjct: 239 NGGASVVREFVNQHEFFIAADKVQSRQG--LEQDPIWLILPDPTQKIPPLIQTLSSLFSE 296
Query: 311 VFNAIENESKVVATVFENKAPNVMHLFIEKVFELKLRPXXXXXXXXXXXXXXXXXXXXXQ 370
+ + IE + V+ VF N V+ F +++F ++ Q
Sbjct: 297 LCSVIEGDCAVIKRVFPN-PELVLQTFFQRIFGQSIQNRLEEVMEIAKGKSNLAYLRTLQ 355
Query: 371 SYFSITNNSVKQLAEFLSN--LKMDSDGKVSACLEKCWKNLFIDIL--FDRSKYFEVEKR 426
+ S V L L N + + +S L + ++L + + D K E R
Sbjct: 356 TVVSSLRKLVADLKTILENRGFSVSDNSPLSLALNQYMEDLLVPFIEVDDYLKREEHSLR 415
Query: 427 TLENVLVQKASDFNISFDSDIRPRSLANKLNEVTDFKSSPELKILTSRSGGRFSQLNLFL 486
+L + + K + + I ++ P L + + + +P G SQ N
Sbjct: 416 SLFRLSLYKYTSYKIRLETP-EPGLLRSLMTPLQGNMVAPT---------GVHSQFNTKT 465
Query: 487 KNKFEKRFE-HENPAQLNITSKKIDRDYFTL---------SYIDLMIKCSVESLARVTEL 536
+ + + EN Q + I DY T+ + I E+L R + L
Sbjct: 466 EGFLLRIADIQENLIQ---SGSFITEDYITIEKNHSHLNSEKVYSFIGWHAEALNRASIL 522
Query: 537 VPAIADDFTYELVETSLIGVID-----SYIESALEVAHAQLNSIDIHRETSIELKFLKYI 591
+ + D + +V +SL+ ++D Y+ L + ++S D + +++L +L I
Sbjct: 523 IS--SQDLS--VVISSLVNLLDKLIREDYVFKELSSIQSYISSHD--KSKNLDLHYLVDI 576
Query: 592 STATEMISIVSAYIKSIVLPLLQNCPSIKRKVIALSNAYFKKCELLMNLLIVETSKLLNQ 651
+++ SAY+ SIV+P S +R+ + + ++ E +N + T L
Sbjct: 577 RECKKIMGYFSAYLMSIVIPFTGVTASSRRETVNILSSSISVIECAVNDVFYATVHALGD 636
Query: 652 KFTLILSKQKRKDFLSKSQDFLDQDTETTTELV-NVLSSVYSQSALYLKNG----NLKAF 706
+ILS ++ + + +++ +D TE + NV + + LY + G +L A
Sbjct: 637 HLEIILSPYRQISY-AMTEEQIDSSTELRQSMTRNVQNYLDYIKNLYHRLGPYDPSLLAL 695
Query: 707 LTKLGDNLFEQLLNHYKKFQVSSTGGVIVTKDIIAFQTAVEDWDVEELNEKFATLRELSN 766
K L L++ + +V++ G +++ DI F + + W ++ ++ KF + +L +
Sbjct: 696 KQKTATMLAAMLISFAFRSKVTAAGALLLQNDINFFHSTLTSWGIDTVDAKFKLILQLLS 755
Query: 767 LFTVQPELLTSLTKEGRLVNVDREIIDEYISKRED 801
L V+ ++L ++ ++ R I E + R D
Sbjct: 756 LLMVKIDVLPAVMQDKRKAGFSEMNIHEVLRLRFD 790
>Hs5730037 [U] KOG3745 Exocyst subunit - Sec10p
Length = 708
Score = 94.4 bits (233), Expect = 6e-19
Identities = 151/731 (20%), Positives = 277/731 (37%), Gaps = 112/731 (15%)
Query: 86 QLTQQVSQMEISHAKSIMVSRGQLKDIVQNYDQLDHKLSAVTQVVSPLGTKLEKSIKQKN 145
+L QQ + AK + + + Q++ +LD +S V V LG +LE +
Sbjct: 66 KLEQQCQKEAKEFAKKVQELQKSNQVAFQHFQELDEHISYVATKVCHLGDQLEGVNTPRQ 125
Query: 146 AYIKSVELISFYASFLE-EGDCPELNKLLESSDKRDICQGAXXXXXXXXXXXXXXXXXVP 204
+++ +L+ ++ FL+ E + + DI Q
Sbjct: 126 RAVEAQKLMKYFNEFLDGELKSDVFTNSEKIKEAADIIQ---------KLHLIAQELPFD 176
Query: 205 KTQEVTQIIEQLATDFEVRILQGFNAAYRENDYSRLHQLAWILDTFNNGVNIIKNFTDKH 264
+ EV I D E +++Q F +A R + SR+ ++A +L F + + + +
Sbjct: 177 RFSEVKSKIASKYHDLECQLIQEFTSAQRRGEISRMREVAAVLLHFKGYSHCVDVYIKQC 236
Query: 265 QFFEESSNFSAKESALFTDDVFKAELMNPDSHILKYDEKVVEYIQSVFNAIENESKVVAT 324
Q E A +D+F+ D+ IL + +K V
Sbjct: 237 Q-----------EGAYLRNDIFE------DAGIL----------------CQRVNKQVGD 263
Query: 325 VFENKAPNVMHLFIEKVFELKLRPXXXXXXXXXXXXXXXXXXXXXQSYFSITNNSVKQLA 384
+F N V+ I+ VFE+KL+ ++ T N +L
Sbjct: 264 IFSNPE-TVLAKLIQNVFEIKLQSFVKEQLEECRKSDAEQYLKNLYDLYTRTTNLSSKLM 322
Query: 385 EFLSNLKMDSDGKVSACLEKCWKNLFIDILFDRSKYFEVEKRTLEN---VLVQKASDFNI 441
EF NL D L K K++FI L Y EVE L++ +++Q+ D
Sbjct: 323 EF--NLGTDKQ----TFLSKLIKSIFISYL---ENYIEVETGYLKSRSAMILQRYYDSKN 373
Query: 442 SFDSDIRP---RSLANKLNEVTDFKSSPELKILTSRSGGRFSQLNLFLKNK--FEKRFEH 496
I + L ++ + T+ P + + +NL + K FE+
Sbjct: 374 HQKRSIGTGGIQDLKERIRQRTNLPLGPSIDTHGETFLSQEVVVNLLQETKQAFERCHRL 433
Query: 497 ENPAQLNITSKKIDRDYFTLSYIDLMIKCSVESLARVTELVPAIADDFTYELVETSLIGV 556
+P+ L + +I FT+ LVE I
Sbjct: 434 SDPSDLPRNAFRI----FTI-------------------------------LVEFLCI-- 456
Query: 557 IDSYIESALEVAHAQLNSIDIHRETSIELKFLKYISTATEMISIVSAYIKSIVLPLLQNC 616
+I+ ALE A + S D + L FL + A + + ++PL+ +
Sbjct: 457 --EHIDYALETGLAGIPSSD---SRNANLYFLDVVQQANTIFHLFDKQFNDHLMPLISSS 511
Query: 617 PSIKRKVIALSNAYFKKCELLMNLLIVETSK-LLNQKFTLILSKQKRKDFLSKSQDFLDQ 675
P + + + ++ E+ ++ I T ++ Q ++ ++QK+ DF K +D +
Sbjct: 512 PKLS-ECLQKKKEIIEQMEMKLDTGIDRTLNCMIGQMKHILAAEQKKTDF--KPEDENNV 568
Query: 676 DTETTTELVNVLSSVYSQSALYLKNG----NLKAFLTKLGDNLFEQLLNHYKKFQVSSTG 731
+ T V V + V Q +KN N+ L +LG + H +++ S G
Sbjct: 569 LIQYTNACVKVCAYVRKQVEK-IKNSMDGKNVDTVLMELGVRFHRLIYEHLQQYSYSCMG 627
Query: 732 GVIVTKDIIAFQTAVEDWDVEELNEKFATLRELSNLFTVQPELLTSLTKEGRLVNVDREI 791
G++ D+ ++ +D+ + + F TL L NL V P+ L + +L N+D+ I
Sbjct: 628 GMLAICDVAEYRKCAKDFKIPMVLHLFDTLHALCNLLVVAPDNLKQVCSGEQLANLDKNI 687
Query: 792 IDEYISKREDY 802
+ ++ R DY
Sbjct: 688 LHSFVQLRADY 698
>CE04152 [U] KOG3745 Exocyst subunit - Sec10p
Length = 659
Score = 75.9 bits (185), Expect = 2e-13
Identities = 59/259 (22%), Positives = 120/259 (45%), Gaps = 11/259 (4%)
Query: 548 LVETSLIGVIDSYIESALEVAHAQLNSIDIHRETSIELKFLKYISTATEMISIVSAYIKS 607
+V+ L + +++ A+E A ++ + +T F ++ T +I ++ +
Sbjct: 400 IVDVLLKYLYGEHLDYAVETGLAGISLAE--SKTEPPAYFFSVVAKCTSVILLMIKQFED 457
Query: 608 IVLPLLQNC---PSIKRKVIALSNAYFKKCELLMNLLIVETSKLLNQKFTLILSKQKRKD 664
+ P+++ PS+ +K + E M+L + + + S+QK+ D
Sbjct: 458 PIFPIIKETIVEPSVAKKW----QQSLRSLESKMSLGLERQLNSIVGYVKFLFSEQKKTD 513
Query: 665 FLSKSQDFLDQDTETTTELVN-VLSSVYSQSALYLKNGNLKAFLTKLGDNLFEQLLNHYK 723
F SQ +D +L + L++ + L NL+A + L LF+ +L H +
Sbjct: 514 FRPDSQQ-IDIRVSPQCQLASRFLANQVAAMELGCDGENLEALQSDLATRLFKFMLTHIQ 572
Query: 724 KFQVSSTGGVIVTKDIIAFQTAVEDWDVEELNEKFATLRELSNLFTVQPELLTSLTKEGR 783
+F +STG V++ D+ +T V W V+ ++ +L+ L+NL V P+ +
Sbjct: 573 QFTYNSTGAVLLLCDVGELRTLVSKWRVQNALTQWESLQALTNLLAVLPDQVNETAHSSL 632
Query: 784 LVNVDREIIDEYISKREDY 802
L NVDR++I +++ R D+
Sbjct: 633 LENVDRQLIHDFVRLRTDF 651
Database: KOG eukaryal database 04/03
Posted date: Apr 14, 2003 1:07 PM
Number of letters in database: 30,389,216
Number of sequences in database: 60,738
Lambda K H
0.317 0.133 0.359
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 40,730,035
Number of Sequences: 60738
Number of extensions: 1580751
Number of successful extensions: 5367
Number of sequences better than 1.0e-05: 4
Number of HSP's better than 0.0 without gapping: 3
Number of HSP's successfully gapped in prelim test: 1
Number of HSP's that attempted gapping in prelim test: 5353
Number of HSP's gapped (non-prelim): 7
length of query: 817
length of database: 30,389,216
effective HSP length: 115
effective length of query: 702
effective length of database: 23,404,346
effective search space: 16429850892
effective search space used: 16429850892
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.6 bits)