ORF STATUS Function Best COG Functional category Pathways and functional systems
r_klactIV4565 good O KOG2738 Posttranslational modification, protein turnover, chaperones Putative methionine aminopeptidase
Only best alignment is shown:
BLASTP 2.2.3 [May-13-2002]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= r_klactIV4565 1554955 1556079 375
(375 letters)
Database: KOG eukaryal database 04/03
60,738 sequences; 30,389,216 total letters
Searching..................................................done
Color Key for Alignment Scores: 
Score E
Sequences producing significant alignments: (bits) Value
YLR244c [O] KOG2738 Putative methionine aminopeptidase 639 0.0
SPBC3E7.10 [O] KOG2738 Putative methionine aminopeptidase 424 e-118
At2g45240 [O] KOG2738 Putative methionine aminopeptidase 387 e-107
Hs22044792 [O] KOG2738 Putative methionine aminopeptidase 382 e-106
7301196 [O] KOG2738 Putative methionine aminopeptidase 364 e-100
CE27601 [O] KOG2738 Putative methionine aminopeptidase 351 9e-97
At1g13270 [O] KOG2738 Putative methionine aminopeptidase 256 5e-68
At4g37040 [O] KOG2738 Putative methionine aminopeptidase 245 9e-65
At3g25740 [O] KOG2738 Putative methionine aminopeptidase 221 2e-57
7297697 [O] KOG2738 Putative methionine aminopeptidase 219 5e-57
7289280 [E] KOG2414 Putative Xaa-Pro aminopeptidase 60 4e-09
7295435 [R] KOG2776 Metallopeptidase 56 8e-08
Hs5453842 [R] KOG2776 Metallopeptidase 55 1e-07
Hs20553033 [R] KOG2776 Metallopeptidase 55 1e-07
Hs20551931 [R] KOG2776 Metallopeptidase 54 5e-07
Hs5803092 [R] KOG2775 Metallopeptidase 50 7e-06
SPBC14C8.03 [R] KOG2775 Metallopeptidase 49 9e-06
>YLR244c [O] KOG2738 Putative methionine aminopeptidase
Length = 387
Score = 639 bits (1648), Expect = 0.0
Identities = 290/368 (78%), Positives = 326/368 (87%)
Query: 8 VRCSSLQCGKVTDSMLKCPICLKQGIEEVFCGESCFKDGYKQHKALHYGTDGSGEVYDPF 67
+ CS LQCG+ T S +KCP+CLKQGI +FC SC+++ YK HKALH DG YDPF
Sbjct: 20 IYCSGLQCGRETSSQMKCPVCLKQGIVSIFCDTSCYENNYKAHKALHNAKDGLEGAYDPF 79
Query: 68 PKFKYTGKLKAQYPLSPKRQVPDEIEKPDWAENGLPIIEQRNDRTNKIPVYNKEQIKRIR 127
PKFKY+GK+KA YPL+P+R VP++I KPDWA NGLP+ EQRNDR N IP+Y K+QIK+IR
Sbjct: 80 PKFKYSGKVKASYPLTPRRYVPEDIPKPDWAANGLPVSEQRNDRLNNIPIYKKDQIKKIR 139
Query: 128 KACALGREVLDVAAAAVRPGITTDEIDEIVHNETIKRGAYPSPLNYYNFPKSVCTSVNEI 187
KAC LGREVLD+AAA VRPGITTDE+DEIVHNETIKRGAYPSPLNYYNFPKS+CTSVNE+
Sbjct: 140 KACMLGREVLDIAAAHVRPGITTDELDEIVHNETIKRGAYPSPLNYYNFPKSLCTSVNEV 199
Query: 188 ICHGVPDKYVLKEGDIVNLDVSLYYQGMHADLNETYYVGETIAKDVINTVETARECLKLA 247
ICHGVPDK VLKEGDIVNLDVSLYYQG HADLNETYYVGE I+K+ +NT ET+RECLKLA
Sbjct: 200 ICHGVPDKTVLKEGDIVNLDVSLYYQGYHADLNETYYVGENISKEALNTTETSRECLKLA 259
Query: 248 IKMCKPGVTFQSLGDCIEKHSKSNKCSVVRTYCGHGVGEFFHCAPSIPHYANNRTPGVMK 307
IKMCKPG TFQ LGD IEKH+ NKCSVVRTYCGHGVGEFFHC+P+IPHYA NRTPGVMK
Sbjct: 260 IKMCKPGTTFQELGDHIEKHATENKCSVVRTYCGHGVGEFFHCSPNIPHYAKNRTPGVMK 319
Query: 308 PGMVFTIEPMINEGVWQDITWPDDWTSSTKDGKVSAQFEQTLLVTENGVEVLTARNKKSP 367
PGMVFTIEPMINEG W+D+TWPDDWTS+T+DGK+SAQFE TLLVTE+GVE+LTARNKKSP
Sbjct: 320 PGMVFTIEPMINEGTWKDMTWPDDWTSTTQDGKLSAQFEHTLLVTEHGVEILTARNKKSP 379
Query: 368 GGPRNRIK 375
GGPR RIK
Sbjct: 380 GGPRQRIK 387
>SPBC3E7.10 [O] KOG2738 Putative methionine aminopeptidase
Length = 379
Score = 424 bits (1090), Expect = e-118
Identities = 209/378 (55%), Positives = 259/378 (68%), Gaps = 9/378 (2%)
Query: 1 MQEKIANVRCSSLQCGKVTDSMLKCPICLKQGIEEVFCGESCFKDGYKQHKALHYGTDGS 60
M +IA C + C D L+CP CL G++ FCG+ CF++ + HK LH +
Sbjct: 1 MATEIAKHICCGIDCNNEADR-LQCPKCLNDGVKSYFCGQECFRNSWNIHKHLHRPPNVE 59
Query: 61 GE---VYDPFPKFKYTGKLKAQYPLSPKRQVPDEIEKPDWAENGLPIIEQRNDRTNKIPV 117
Y+PFPKF + G LK YPLSP R+VP I++PD+A+ G+ EQ R+ K+
Sbjct: 60 KREDGTYNPFPKFHFAGSLKPVYPLSPIRKVPPHIKRPDYAKTGVSRSEQIEGRSFKLKR 119
Query: 118 YNKEQIKRIRKACALGREVLDVAAAAVRPGITTDEIDEIVHNETIKRGAYPSPLNYYNFP 177
++ + +RK C LGREVLD AAAAVRPG TTDE+D IVHN I+R +PS LNYY FP
Sbjct: 120 LTPKEQEGMRKVCRLGREVLDAAAAAVRPGTTTDELDSIVHNACIERDCFPSTLNYYAFP 179
Query: 178 KSVCTSVNEIICHGVPDKYVLKEGDIVNLDVSLYYQGMHADLNETYYVGETIA--KDVIN 235
KSVCTSVNEIICHG+PD+ L++GDIVN+DVSLY+ G H DLNETYYVG+ D++
Sbjct: 180 KSVCTSVNEIICHGIPDQRPLEDGDIVNIDVSLYHNGFHGDLNETYYVGDKAKANPDLVC 239
Query: 236 TVETARECLKLAIKMCKPGVTFQSLGDCIEKHSKS---NKCSVVRTYCGHGVGEFFHCAP 292
VE R L AI KPGV FQ G+ IEKH+ S + SVVRTYCGHG+ + FHC+P
Sbjct: 240 LVENTRIALDKAIAAVKPGVLFQEFGNIIEKHTNSITEKQISVVRTYCGHGINQLFHCSP 299
Query: 293 SIPHYANNRTPGVMKPGMVFTIEPMINEGVWQDITWPDDWTSSTKDGKVSAQFEQTLLVT 352
SIPHY++N+ PG+ +PGM FTIEPM+ G +DITWPDDWTSST G+ SAQFE TLLVT
Sbjct: 300 SIPHYSHNKAPGIARPGMTFTIEPMLTLGPARDITWPDDWTSSTASGRCSAQFEHTLLVT 359
Query: 353 ENGVEVLTARNKKSPGGP 370
E G EVLTAR SPGGP
Sbjct: 360 ETGCEVLTARLPNSPGGP 377
>At2g45240 [O] KOG2738 Putative methionine aminopeptidase
Length = 398
Score = 387 bits (993), Expect = e-107
Identities = 196/387 (50%), Positives = 252/387 (64%), Gaps = 30/387 (7%)
Query: 5 IANVRCSSLQCGKVTDSMLKCPICLKQGI---EEVFCGESCFKDGYKQHKALHYGTDGS- 60
IA + C+ +C K + L+CP C+ + + FC + CFK + HK++H S
Sbjct: 10 IATLSCA--RCEK--PAHLQCPKCIDLKLPREQASFCTQECFKAAWSSHKSVHVKAQLSS 65
Query: 61 -------------------GEVYDP-FPKFKYTGKLKAQYPLSPKRQVPDEIEKPDWAEN 100
G+ P P F +TG LK QYP+S KR VP EIEKPDWA +
Sbjct: 66 IGDQNSDLISQGWLYCVKKGQARTPKLPHFDWTGPLK-QYPISTKRVVPAEIEKPDWAID 124
Query: 101 GLPIIEQRNDRTNKIPVYNKEQIKRIRKACALGREVLDVAAAAVRPGITTDEIDEIVHNE 160
G P +E +D + + + EQI+R+R+ C + REVLD AA + PG+TTDEID +VH
Sbjct: 125 GTPKVEPNSDLQHVVEIKTPEQIQRMRETCKIAREVLDAAARVIHPGVTTDEIDRVVHEA 184
Query: 161 TIKRGAYPSPLNYYNFPKSVCTSVNEIICHGVPDKYVLKEGDIVNLDVSLYYQGMHADLN 220
TI G YPSPLNYY FPKS CTSVNE+ICHG+PD L++GDIVN+DV++ Y+G H DLN
Sbjct: 185 TIAAGGYPSPLNYYFFPKSCCTSVNEVICHGIPDARKLEDGDIVNVDVTVCYKGCHGDLN 244
Query: 221 ETYYVGETIAKDVINTVETARECLKLAIKMCKPGVTFQSLGDCIEKHSKSNKCSVVRTYC 280
ETY+VG + + V+ ECL+ AI + KPGV F+ +G+ + +H+ + SVVR+YC
Sbjct: 245 ETYFVG-NVDEASRQLVKCTYECLEKAIAIVKPGVRFREIGEIVNRHATMSGLSVVRSYC 303
Query: 281 GHGVGEFFHCAPSIPHYANNRTPGVMKPGMVFTIEPMINEGVWQDITWPDDWTSSTKDGK 340
GHG+G+ FHCAP+IPHYA N+ GVMK G FTIEPMIN G W+D TWPD WT+ T DGK
Sbjct: 304 GHGIGDLFHCAPNIPHYARNKAVGVMKAGQTFTIEPMINAGGWRDRTWPDGWTAVTADGK 363
Query: 341 VSAQFEQTLLVTENGVEVLTARNKKSP 367
SAQFE TLLVTE GVEVLTAR SP
Sbjct: 364 RSAQFEHTLLVTETGVEVLTARLPSSP 390
>Hs22044792 [O] KOG2738 Putative methionine aminopeptidase
Length = 386
Score = 382 bits (980), Expect = e-106
Identities = 188/363 (51%), Positives = 246/363 (66%), Gaps = 17/363 (4%)
Query: 16 GKVTDSMLKCPICLKQGIE-EVFCGESCFKDGYKQHKALHYGTDGS------------GE 62
G +++ L+CP C+K GI+ FC + CFK + HK LH G+
Sbjct: 13 GCSSEAKLQCPTCIKLGIQGSYFCSQECFKGSWATHKLLHKKAKDEKAKREVSSWTVEGD 72
Query: 63 VY-DPFPKFKYTGKLKAQYPLSPKRQVPDEIEKPDWAEN--GLPIIEQRNDRTNKIPVYN 119
+ DP+ ++YTGKL+ YPL P R VP I++PD+A++ G+ EQ T++I + +
Sbjct: 73 INTDPWAGYRYTGKLRPHYPLMPTRPVPSYIQRPDYADHPLGMSESEQALKGTSQIKLLS 132
Query: 120 KEQIKRIRKACALGREVLDVAAAAVRPGITTDEIDEIVHNETIKRGAYPSPLNYYNFPKS 179
E I+ +R C L REVLDVAA ++PG+TT+EID VH I R YPSPLNYYNFPKS
Sbjct: 133 SEDIEGMRLVCRLAREVLDVAAGMIKPGVTTEEIDHAVHLACIARNCYPSPLNYYNFPKS 192
Query: 180 VCTSVNEIICHGVPDKYVLKEGDIVNLDVSLYYQGMHADLNETYYVGETIAKDVINTVET 239
CTSVNE+ICHG+PD+ L+EGDIVN+D++LY G H DLNET++VGE + V+T
Sbjct: 193 CCTSVNEVICHGIPDRRPLQEGDIVNVDITLYRNGYHGDLNETFFVGE-VDDGARKLVQT 251
Query: 240 ARECLKLAIKMCKPGVTFQSLGDCIEKHSKSNKCSVVRTYCGHGVGEFFHCAPSIPHYAN 299
ECL AI KPGV ++ LG+ I+KH+++N SVVR+YCGHG+ + FH AP++PHYA
Sbjct: 252 TYECLMQAIDAVKPGVRYRELGNIIQKHAQANGFSVVRSYCGHGIHKLFHTAPNVPHYAK 311
Query: 300 NRTPGVMKPGMVFTIEPMINEGVWQDITWPDDWTSSTKDGKVSAQFEQTLLVTENGVEVL 359
N+ GVMK G VFTIEPMI EG WQD TWPD WT+ T+DGK SAQFE TLLVT+ G E+L
Sbjct: 312 NKAVGVMKSGHVFTIEPMICEGGWQDETWPDGWTAVTRDGKRSAQFEHTLLVTDTGCEIL 371
Query: 360 TAR 362
T R
Sbjct: 372 TRR 374
>7301196 [O] KOG2738 Putative methionine aminopeptidase
Length = 374
Score = 364 bits (935), Expect = e-100
Identities = 184/367 (50%), Positives = 248/367 (67%), Gaps = 14/367 (3%)
Query: 9 RCSSLQCGKVTDSMLKCPICLKQGIE-EVFCGESCFKDGYKQHKALHY---GTDGSGE-- 62
+C + CGK D+ L+CP CLK GI+ FC + CFK +K+HKA+H G S E
Sbjct: 4 KCETTNCGK--DATLQCPTCLKLGIKGSFFCSQPCFKGFWKEHKAIHALAAGASNSAEQD 61
Query: 63 -VYDPFPKFKYTGKLKAQYPLSPKRQVPDEIEKPDWAEN--GLPIIEQRNDRTNKIPVYN 119
Y+P+P F++TGKL+ +P +PKR VP+ I++PD+A++ G + E+ R KI V +
Sbjct: 62 GAYNPWPHFRFTGKLRP-FPQTPKRTVPNAIQRPDYADHPAGRSLSEEAL-RGTKIKVLD 119
Query: 120 KEQIKRIRKACALGREVLDVAAAAVRPGITTDEIDEIVHNETIKRGAYPSPLNYYNFPKS 179
E+I+ +R A LGRE LD A AV GITTDE+D +VH I+R YPSPLNYYNFPKS
Sbjct: 120 DEEIEGMRVAGRLGRECLDEGAKAVEVGITTDELDRLVHEAAIERECYPSPLNYYNFPKS 179
Query: 180 VCTSVNEIICHGVPDKYVLKEGDIVNLDVSLYYQGMHADLNETYYVGETIAKDVINTVET 239
CTSVNE+ICHG+PD+ L++GD+ N+DV++Y++G H DLNET++VG K V+
Sbjct: 180 CCTSVNEVICHGIPDQRPLQDGDLCNIDVTVYHRGFHGDLNETFFVGNVSEKHK-KLVQV 238
Query: 240 ARECLKLAIKMCKPGVTFQSLGDCIEKHSKSNKCSVVRTYCGHGVGEFFHCAPSIPHYAN 299
E L AI+ +PG ++ +G+ I+K+ + SVVR+YCGHG+ FH AP++PHYA
Sbjct: 239 THEALSKAIEFVRPGEKYRDIGNVIQKYVAPHGFSVVRSYCGHGIHRVFHTAPNVPHYAK 298
Query: 300 NRTPGVMKPGMVFTIEPMINEGVWQDITWPDDWTSSTKDGKVSAQFEQTLLVTENGVEVL 359
N GVM PG FTIEPMI+ GV + TWPDDWT+ T DG SAQFEQTLLV E G E+L
Sbjct: 299 NSAVGVMAPGHCFTIEPMISVGVQKAETWPDDWTAVTADGLYSAQFEQTLLVNETGCEIL 358
Query: 360 TARNKKS 366
T R + +
Sbjct: 359 TKRRENN 365
>CE27601 [O] KOG2738 Putative methionine aminopeptidase
Length = 388
Score = 351 bits (901), Expect = 9e-97
Identities = 168/348 (48%), Positives = 233/348 (66%), Gaps = 7/348 (2%)
Query: 23 LKCPICLKQGIEEV-FCGESCFKDGYKQHKALHYGTDGSGEVYDPFPKFKYTGKLKAQYP 81
L+CP C+K + + FC +SCFK + HK H +G Y+P+P + +TG L+
Sbjct: 18 LRCPTCIKMSLPDAYFCDQSCFKAFWPIHKFSHSDVNGP---YNPWPCYSFTGSLRPGR- 73
Query: 82 LSPKRQVPDEIEKPDWA--ENGLPIIEQRNDRTNKIPVYNKEQIKRIRKACALGREVLDV 139
++ +R VPD I +PD+A G+ + E+++ I V E+ + ++ AC LGRE L+
Sbjct: 74 VTDRRPVPDHIPRPDYALHPQGVSLEERQSKSERVIKVLTDEEKEGLKVACKLGRECLNE 133
Query: 140 AAAAVRPGITTDEIDEIVHNETIKRGAYPSPLNYYNFPKSVCTSVNEIICHGVPDKYVLK 199
AA A PG+TT+EID +VH I+R YPSPL YY FPKS CTSVNE+ICHG+PD L+
Sbjct: 134 AAKACGPGVTTEEIDRVVHEAAIERDCYPSPLGYYKFPKSCCTSVNEVICHGIPDMRKLE 193
Query: 200 EGDIVNLDVSLYYQGMHADLNETYYVGETIAKDVINTVETARECLKLAIKMCKPGVTFQS 259
GD+ N+DV++Y++G H DLNET+ VG+ + ++ V+ ECL+ AI + KPGV F+
Sbjct: 194 NGDLCNVDVTVYHRGFHGDLNETFLVGDKVDEESRKLVKVTFECLQQAIAIVKPGVKFRE 253
Query: 260 LGDCIEKHSKSNKCSVVRTYCGHGVGEFFHCAPSIPHYANNRTPGVMKPGMVFTIEPMIN 319
+G+ I+KH+ +N SVV+ YCGHG+ FH AP++PHYA N GVMK G FTIEPMIN
Sbjct: 254 IGNVIQKHANANGFSVVKGYCGHGIHRLFHTAPNVPHYAKNNATGVMKAGNSFTIEPMIN 313
Query: 320 EGVWQDITWPDDWTSSTKDGKVSAQFEQTLLVTENGVEVLTARNKKSP 367
G + D WPDDWT+ T+DG+ SAQFEQTLLVT+ G E+LT R+ P
Sbjct: 314 AGTYHDDKWPDDWTAVTRDGRRSAQFEQTLLVTDTGCEILTKRDGNRP 361
>At1g13270 [O] KOG2738 Putative methionine aminopeptidase
Length = 369
Score = 256 bits (653), Expect = 5e-68
Identities = 126/280 (45%), Positives = 179/280 (63%), Gaps = 9/280 (3%)
Query: 82 LSPKRQVPDEIEKPDWAENG-LPIIEQRNDRTNKIPVYNKEQIKRIRKACALGREVLDVA 140
+SP+ VPD I +P + E+G LP D +++ + E I ++R AC L VL+ A
Sbjct: 96 VSPRLLVPDHIPRPPYVESGVLP------DISSEFQIPGPEGIAKMRAACELAARVLNYA 149
Query: 141 AAAVRPGITTDEIDEIVHNETIKRGAYPSPLNYYNFPKSVCTSVNEIICHGVPDKYVLKE 200
V+P +TT+EID+ VH+ I+ GAYPSPL Y FPKSVCTSVNE +CHG+PD L+
Sbjct: 150 GTLVKPSVTTNEIDKAVHDMIIEAGAYPSPLGYGGFPKSVCTSVNECMCHGIPDSRQLQS 209
Query: 201 GDIVNLDVSLYYQGMHADLNETYYVGETIAKDVINTVETARECLKLAIKMCKPGVTFQSL 260
GDI+N+DV++Y G H D + T++ GE + + V+ ECL+ I +CK G +F+ +
Sbjct: 210 GDIINIDVTVYLDGYHGDTSRTFFCGE-VDEGFKRLVKVTEECLERGIAVCKDGASFKKI 268
Query: 261 GDCIEKHSKSNKCSVVRTYCGHGVGEFFHCAPSIPHYANNRTPGVMKPGMVFTIEPMINE 320
G I +H++ +VV + GHGVG FH P I HY N+ PG+M G FTIEP++
Sbjct: 269 GKRISEHAEKFGYNVVERFVGHGVGPVFHSEPLIYHYRNDE-PGLMVEGQTFTIEPILTI 327
Query: 321 GVWQDITWPDDWTSSTKDGKVSAQFEQTLLVTENGVEVLT 360
G + +TWPD+WT+ T DG V+AQFE T+L+T G E+LT
Sbjct: 328 GTTECVTWPDNWTTLTADGGVAAQFEHTILITRTGSEILT 367
>At4g37040 [O] KOG2738 Putative methionine aminopeptidase
Length = 305
Score = 245 bits (625), Expect = 9e-65
Identities = 128/289 (44%), Positives = 176/289 (60%), Gaps = 9/289 (3%)
Query: 74 GKLKAQYP--LSPKRQVPDEIEKPDWAENGLPIIEQRNDRTNKIPVYNKEQIKRIRKACA 131
GK K P +SP+R VP I KP + ++ Q ++ + V++K+ I+ +R +
Sbjct: 22 GKRKRLRPGNVSPRRPVPGHITKPPYVDS-----LQAPGISSGLEVHDKKGIECMRASGI 76
Query: 132 LGREVLDVAAAAVRPGITTDEIDEIVHNETIKRGAYPSPLNYYNFPKSVCTSVNEIICHG 191
L V D A V+PG+TTDEIDE VHN I+ GAYPSPL Y FPKSVCTSVNE ICHG
Sbjct: 77 LAARVRDYAGTLVKPGVTTDEIDEAVHNMIIENGAYPSPLGYGGFPKSVCTSVNECICHG 136
Query: 192 VPDKYVLKEGDIVNLDVSLYYQGMHADLNETYYVGETIAKDVINTVETARECLKLAIKMC 251
+PD L++GDI+N+DV++Y G H D + T++ G + + VE +E L AI +C
Sbjct: 137 IPDSRPLEDGDIINIDVTVYLNGYHGDTSATFFCG-NVDEKAKKLVEVTKESLDKAISIC 195
Query: 252 KPGVTFQSLGDCIEKHSKSNKCSVVRTYCGHGVGEFFHCAPSIPHYANNRTPGVMKPGMV 311
PGV ++ +G I + +K VVR + GHGVG FH P + H+ NN G M
Sbjct: 196 GPGVEYKKIGKVIHDLADKHKYGVVRQFVGHGVGSVFHADPVVLHFRNNEA-GRMVLNQT 254
Query: 312 FTIEPMINEGVWQDITWPDDWTSSTKDGKVSAQFEQTLLVTENGVEVLT 360
FTIEPM+ G I W D+WT T+D +SAQFE T+L+T++G E+LT
Sbjct: 255 FTIEPMLTIGSRNPIMWDDNWTVVTEDASLSAQFEHTILITKDGAEILT 303
>At3g25740 [O] KOG2738 Putative methionine aminopeptidase
Length = 344
Score = 221 bits (562), Expect = 2e-57
Identities = 117/281 (41%), Positives = 170/281 (59%), Gaps = 10/281 (3%)
Query: 82 LSPKRQVPDEIEKPDWAENG-LPIIEQRNDRTNKIPVYNKEQIKRIRKACALGREVLDVA 140
+SP+ VPD I KP + E+ +P I ++++ + + I +++KAC L VLD A
Sbjct: 69 VSPRLSVPDHILKPLYVESSKVPEI------SSELQIPDSIGIVKMKKACELAARVLDYA 122
Query: 141 AAAVRPGITTDEIDEIVHNETIKRGAYPSPLNYYNFPKSVCTSVNEIICHGVPDKYVLKE 200
VRP +TTDEID+ VH I+ GAYPSPL Y FPKSVCTSVNE + HG+PD L+
Sbjct: 123 GTLVRPFVTTDEIDKAVHQMVIEFGAYPSPLGYGGFPKSVCTSVNECMFHGIPDSRPLQN 182
Query: 201 GDIVNLDVSLYYQGMHADLNETYYVGETIAKDVINTVETARECLKLAIKMCKPGVTFQSL 260
GDI+N+DV++Y G H D ++T+ G+ + + V+ ECL+ I +CK G +F+ +
Sbjct: 183 GDIINIDVAVYLDGYHGDTSKTFLCGD-VNGSLKQLVKVTEECLEKGISVCKDGASFKQI 241
Query: 261 GDCIEKHSKSNKCSVVRTYCGHGVGEFFHCAPSIPHYAN-NRTPGVMKPGMVFTIEPMIN 319
G I +H+ ++ R + GHGVG H P I ++N + M G FT+EP++
Sbjct: 242 GKIISEHAAKYGYNMER-FIGHGVGTVLHSEPLIYLHSNYDYELEYMIEGQTFTLEPILT 300
Query: 320 EGVWQDITWPDDWTSSTKDGKVSAQFEQTLLVTENGVEVLT 360
G + +TWPD WT T DG +AQFE T+L+T G E+LT
Sbjct: 301 IGTTEFVTWPDKWTIVTADGGPAAQFEHTILITTTGAEILT 341
>7297697 [O] KOG2738 Putative methionine aminopeptidase
Length = 307
Score = 219 bits (558), Expect = 5e-57
Identities = 110/279 (39%), Positives = 160/279 (56%), Gaps = 6/279 (2%)
Query: 82 LSPKRQVPDEIEKPDWAENGLPIIEQRNDRTNKIPVYNKEQIKRIRKACALGREVLDVAA 141
+SP+R VP+EI+KP + +P + + ++ QI +R + L +L
Sbjct: 32 VSPERFVPEEIKKPAYYFKNMP----PGNTLGSPEIKSQVQIDAMRLSGRLAARILRECG 87
Query: 142 AAVRPGITTDEIDEIVHNETIKRGAYPSPLNYYNFPKSVCTSVNEIICHGVPDKYVLKEG 201
G TTD+ID H ++ AYPSPL Y FPKS+CTS+N I CHG+PD L +G
Sbjct: 88 KLATVGTTTDQIDAFAHERILESKAYPSPLRYAGFPKSICTSINNIACHGIPDDRQLADG 147
Query: 202 DIVNLDVSLYYQGMHADLNETYYVGETIAKDVINTVETARECLKLAIKMCKPGVTFQSLG 261
DI+N+DV+++ G H D +ET+ VG + VE + CL I +C PGV F +G
Sbjct: 148 DIINIDVTVFLNGYHGDCSETFRVGNVDERGGF-LVEATKSCLDQCISLCGPGVEFNEIG 206
Query: 262 DCIEKHSKSNKCSVVRTYCGHGVGEFFHCAPSIPHYANNRTPGVMKPGMVFTIEPMINEG 321
I+++ + + + + GHG+G +FH P I HY N PG M+PGM FTIEP+++ G
Sbjct: 207 KFIDRYCDEHDLASIAAFIGHGIGSYFHGPPEILHY-YNEIPGKMQPGMTFTIEPILSLG 265
Query: 322 VWQDITWPDDWTSSTKDGKVSAQFEQTLLVTENGVEVLT 360
+ D WT+ + DG SAQFE T+L+TE G E+LT
Sbjct: 266 GAEIAVLQDGWTAISLDGARSAQFEHTILITETGTEILT 304
>7289280 [E] KOG2414 Putative Xaa-Pro aminopeptidase
Length = 545
Score = 60.5 bits (145), Expect = 4e-09
Identities = 76/313 (24%), Positives = 126/313 (39%), Gaps = 67/313 (21%)
Query: 95 PDWAENGLPIIEQRNDRTNKIPVY----------NKEQIKRIRKACALGREVLDVAAAAV 144
P AEN L + N + +P Y ++++++ +R+ C + + A
Sbjct: 238 PSLAENMLRL--SGNQQRPLLPAYTFLEAMRLLKSRDEMQLMRRTCDIASRSFNEVMAET 295
Query: 145 RPGITTDEIDEIVHNETIKRGAYPSPLNYYNFPKSVCTSVNEIICHGVPDKYVLKEGDIV 204
RPG + + + + R A +Y +P V N + H V + +L + D+V
Sbjct: 296 RPGQSEHHLFAAIDYKCRMRNA-----SYLAYPPVVAAGKNATVIHYVANSQLLGQQDLV 350
Query: 205 NLDVSLYYQGMHADLNET--------------YYVGETIAKDVINTV-----ETARE--- 242
+D Y G +D+ T Y + + +++I V ET +
Sbjct: 351 LMDAGCEYGGYTSDITRTWPASGVFTEPQRTLYDMLHQLQEEIIGNVMKPGGETLDQLFE 410
Query: 243 --CLKLAIKMCKPGVTFQSLGDCIEKHSKSNKCSVVRTYCGHGVGEFF----HCAPSIPH 296
C KL + + G+ +S + E S+ + +C H V + H P +P
Sbjct: 411 TTCYKLGKYLQEIGLVGKSFSEYKELVSQGYR------FCPHHVSHYLGMDVHDTPHVPR 464
Query: 297 YANNRTPGVMKPGMVFTIEPMINEGVWQDI-TWPDDWTSSTKDGKVSAQFEQTLLVTENG 355
N R + PGMVFT+EP I G QD P ++ + + E LL+ ENG
Sbjct: 465 --NTR----IVPGMVFTVEPGIYIG--QDCGDVPPEFRG------IGIRIEDDLLINENG 510
Query: 356 -VEVLTARNKKSP 367
VEVLT K P
Sbjct: 511 HVEVLTEACVKDP 523
>7295435 [R] KOG2776 Metallopeptidase
Length = 391
Score = 56.2 bits (134), Expect = 8e-08
Identities = 34/115 (29%), Positives = 55/115 (47%), Gaps = 8/115 (6%)
Query: 181 CTSVNEIICHGVPDK----YVLKEGDIVNLDVSLYYQGMHADLNETYYVG----ETIAKD 232
C SVN +CH P K Y LK GD+V +D+ + G A T VG + I+
Sbjct: 79 CLSVNNCVCHFSPAKNDADYTLKAGDVVKIDLGAHIDGFIAVAAHTIVVGAAADQKISGR 138
Query: 233 VINTVETARECLKLAIKMCKPGVTFQSLGDCIEKHSKSNKCSVVRTYCGHGVGEF 287
+ + A ++ A+++ K G SL D +++ S+S KC + H + +F
Sbjct: 139 QADVILAAYWAVQAALRLLKSGANNYSLTDAVQQISESYKCKPIEGMLSHELKQF 193
>Hs5453842 [R] KOG2776 Metallopeptidase
Length = 394
Score = 55.5 bits (132), Expect = 1e-07
Identities = 33/115 (28%), Positives = 57/115 (48%), Gaps = 10/115 (8%)
Query: 176 FPKSVCTSVNEIICHGVPDK----YVLKEGDIVNLDVSLYYQGMHADLNETYYV----GE 227
FP S+ SVN +CH P K Y+LKEGD+V +D+ ++ G A++ T+ V G
Sbjct: 76 FPTSI--SVNNCVCHFSPLKSDQDYILKEGDLVKIDLGVHVDGFIANVAHTFVVDVAQGT 133
Query: 228 TIAKDVINTVETARECLKLAIKMCKPGVTFQSLGDCIEKHSKSNKCSVVRTYCGH 282
+ + ++ A C + A+++ KPG + + K + S C+ + H
Sbjct: 134 QVTGRKADVIKAAHLCAEAALRLVKPGNQNTQVTEAWNKVAHSFNCTPIEGMLSH 188
>Hs20553033 [R] KOG2776 Metallopeptidase
Length = 210
Score = 55.5 bits (132), Expect = 1e-07
Identities = 33/115 (28%), Positives = 57/115 (48%), Gaps = 10/115 (8%)
Query: 176 FPKSVCTSVNEIICHGVPDK----YVLKEGDIVNLDVSLYYQGMHADLNETYYV----GE 227
FP S+ SVN +CH P K Y+LKEGD+V +D+ ++ G A++ T+ V G
Sbjct: 76 FPTSI--SVNNCVCHFSPLKSDQDYILKEGDLVKIDLGVHVDGFIANVAHTFVVDVAQGT 133
Query: 228 TIAKDVINTVETARECLKLAIKMCKPGVTFQSLGDCIEKHSKSNKCSVVRTYCGH 282
+ + ++ A C + A+++ KPG + + K + S C+ + H
Sbjct: 134 QVTGRKADVIKAAHLCAEAALRLVKPGNQNTQVTEAWNKVAHSFNCTPIEGMLSH 188
>Hs20551931 [R] KOG2776 Metallopeptidase
Length = 307
Score = 53.5 bits (127), Expect = 5e-07
Identities = 29/87 (33%), Positives = 47/87 (53%), Gaps = 10/87 (11%)
Query: 176 FPKSVCTSVNEIICHGVP----DKYVLKEGDIVNLDVSLYYQGMHADLNETYYV----GE 227
FP S+ SVN +CH P Y+LKEGD+V +D+ +Y G A++ T+ V G
Sbjct: 54 FPTSI--SVNNCVCHFSPLESGQDYILKEGDLVKIDLGVYVDGFIANVAHTFVVDVAQGT 111
Query: 228 TIAKDVINTVETARECLKLAIKMCKPG 254
+ + ++ A C + A+++ KPG
Sbjct: 112 QVTGRKADVIKAAHLCAEAALRLVKPG 138
>Hs5803092 [R] KOG2775 Metallopeptidase
Length = 478
Score = 49.7 bits (117), Expect = 7e-06
Identities = 50/207 (24%), Positives = 86/207 (41%), Gaps = 18/207 (8%)
Query: 127 RKACALGREVLDVAAAAVRPGITTDEIDEIVHN---ETIKRGAYPSPLNYYNFPKSVCTS 183
R+A R+V + ++PG+T EI E + + + IK + L FP S
Sbjct: 170 REAAEAHRQVRKYVMSWIKPGMTMIEICEKLEDCSRKLIKENGLNAGL---AFPTG--CS 224
Query: 184 VNEIICHGVP---DKYVLKEGDIVNLDVSLYYQGMHADLNETYYVG---ETIAKDVINTV 237
+N H P D VL+ DI +D + G D T +T+ K V +
Sbjct: 225 LNNCAAHYTPNAGDTTVLQYDDICKIDFGTHISGRIIDCAFTVTFNPKYDTLLKAVKDAT 284
Query: 238 ETARECLKLAIKMCKPGVTFQSLGDC--IEKHSKSNKCSVVRTYCGHGVGEF-FHCAPSI 294
T +C + +++C G Q + + +E K+ + +R GH +G++ H ++
Sbjct: 285 NTGIKCAGIDVRLCDVGEAIQEVMESYEVEIDGKTYQVKPIRNLNGHSIGQYRIHAGKTV 344
Query: 295 PHYANNRTPGVMKPGMVFTIEPMINEG 321
P M+ G V+ IE + G
Sbjct: 345 PIVKGGEATR-MEEGEVYAIETFGSTG 370
>SPBC14C8.03 [R] KOG2775 Metallopeptidase
Length = 426
Score = 49.3 bits (116), Expect = 9e-06
Identities = 48/239 (20%), Positives = 94/239 (39%), Gaps = 22/239 (9%)
Query: 96 DWAENGLPIIEQRNDRTNKIPVYNKEQIKRIRKACALGREVLDVAAAAVRPGITTDEIDE 155
D+AE+ L ++ + N +Q +R+A + R+ A + ++PG++ ++
Sbjct: 89 DYAEDNL--WRTTDEEKRALDRQNFDQYNDLRRAAEVHRQARQYAQSVIKPGMSMMDVVN 146
Query: 156 IVHNETIKRGAYPSPLNYYNFPKSVCTSVNEIICHGVP---DKYVLKEGDIVNLDVSLYY 212
+ N T + FP V S+N H P D +LKE D++ +D+ ++
Sbjct: 147 TIENTTRALVEEDGLKSGIGFPTGV--SLNHCAAHYTPNAGDTTILKEKDVMKVDIGVHV 204
Query: 213 QGMHADLNETYYVGETIAKDVINTVETARECLKLAIKMCKPGVTFQSLGDCIEK------ 266
G D T + N + + I+ +G+ I++
Sbjct: 205 NGRIVDSAFTM----SFDPQYDNLLAAVKAATNKGIEEAGIDARLNEIGEAIQEVMESYE 260
Query: 267 ---HSKSNKCSVVRTYCGHGVGEF-FHCAPSIPHYANNRTPGVMKPGMVFTIEPMINEG 321
+ K+++ +R CGH + + H S+P M+ G +F IE + G
Sbjct: 261 VEINGKTHQVKSIRNLCGHNLDPYIIHGGKSVP-IVKGGEEIKMEEGEIFAIETFGSTG 318
Database: KOG eukaryal database 04/03
Posted date: Apr 14, 2003 1:07 PM
Number of letters in database: 30,389,216
Number of sequences in database: 60,738
Lambda K H
0.317 0.136 0.419
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 25,355,164
Number of Sequences: 60738
Number of extensions: 1193929
Number of successful extensions: 2547
Number of sequences better than 1.0e-05: 17
Number of HSP's better than 0.0 without gapping: 10
Number of HSP's successfully gapped in prelim test: 7
Number of HSP's that attempted gapping in prelim test: 2495
Number of HSP's gapped (non-prelim): 21
length of query: 375
length of database: 30,389,216
effective HSP length: 108
effective length of query: 267
effective length of database: 23,829,512
effective search space: 6362479704
effective search space used: 6362479704
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.6 bits)