ORF STATUS Function Best COG Functional category Pathways and functional systems
r_klactIV4623 good H KOG3220 Coenzyme transport and metabolism Similar to bacterial dephospho-CoA kinase
Only best alignment is shown:
BLASTP 2.2.3 [May-13-2002]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= r_klactIV4623 1579946 1579089 -286
(286 letters)
Database: KOG eukaryal database 04/03
60,738 sequences; 30,389,216 total letters
Searching..................................................done
Color Key for Alignment Scores: 
Score E
Sequences producing significant alignments: (bits) Value
YDR196c [H] KOG3220 Similar to bacterial dephospho-CoA kinase 271 1e-72
SPCC14G10.01 [H] KOG3220 Similar to bacterial dephospho-CoA kinase 174 1e-43
CE23950 [H] KOG3220 Similar to bacterial dephospho-CoA kinase 141 9e-34
7298862 [H] KOG3220 Similar to bacterial dephospho-CoA kinase 141 9e-34
Hs19923601 [H] KOG3220 Similar to bacterial dephospho-CoA kinase 133 3e-31
At2g27490 [H] KOG3220 Similar to bacterial dephospho-CoA kinase 132 4e-31
Hs22063771 [H] KOG3220 Similar to bacterial dephospho-CoA kinase 100 4e-21
HsM13376838_2 [H] KOG3220 Similar to bacterial dephospho-CoA kinase 75 8e-14
Hs21489977_2 [H] KOG3220 Similar to bacterial dephospho-CoA kinase 75 8e-14
CE28145_2 [H] KOG3220 Similar to bacterial dephospho-CoA kinase 52 7e-07
>YDR196c [H] KOG3220 Similar to bacterial dephospho-CoA kinase
Length = 241
Score = 271 bits (692), Expect = 1e-72
Identities = 124/236 (52%), Positives = 181/236 (76%)
Query: 1 MLIIGLTGGIACGKSTVSSRLKTHYRIPVIDADAIARRILDPGQNAYKRVIRYFSGKVSN 60
ML++GLTGGIACGKSTVS RL+ Y++P++DAD IAR++++PGQNAY +++ YF K+ N
Sbjct: 1 MLVVGLTGGIACGKSTVSRRLRDKYKLPIVDADKIARQVVEPGQNAYDQIVLYFKDKIPN 60
Query: 61 LVLADGSINRAALGAYIFANPEERKVLNGITHPEVRHAILLKILMNYLKFHAMCILDVPL 120
L+L DG +NR ALG ++F++ E+ + LNGITHP +R+A+ +I YLK + MC+LDVPL
Sbjct: 61 LLLEDGHLNREALGKWVFSHKEDLQALNGITHPAIRYAMFKEIGYYYLKGYRMCVLDVPL 120
Query: 121 LFEANLDIICGITVCVVCDRDLQLQRLMERNPELTEELALARIEAQMSMYDRISRSDYLI 180
LFE NLD ICG+TV V+C ++LQL+RLM RNPEL+EE A R+ +QMS +R++RSDY++
Sbjct: 121 LFEGNLDSICGVTVSVICTQELQLERLMTRNPELSEEDAKNRLNSQMSTEERMARSDYIL 180
Query: 181 DNNGDIKELFGNIDGLLTYIKPSAITVWLEYFPPYGFVAALSVIFSRYLKQRWPSK 236
NN + +L+ I+ ++ I+PS + LEYFPP+G V+A S++ SR L ++ +K
Sbjct: 181 QNNSTLVDLYEQIESVVKKIQPSKLRTVLEYFPPFGAVSASSIVMSRLLMKKLQNK 236
>SPCC14G10.01 [H] KOG3220 Similar to bacterial dephospho-CoA kinase
Length = 236
Score = 174 bits (442), Expect = 1e-43
Identities = 90/203 (44%), Positives = 133/203 (65%), Gaps = 3/203 (1%)
Query: 1 MLIIGLTGGIACGKSTVSSRLKTHYRIPVIDADAIARRILDPGQNAYKRVIRYFSGKVSN 60
MLI+GLTG IA GKSTVS + Y I +IDAD +AR++++P ++ + F +V +
Sbjct: 1 MLILGLTGSIATGKSTVSREFQEKYHIKIIDADVLARKVVEPNTPCLIKIQKEFGNEVLH 60
Query: 61 LVLADGSINRAALGAYIFANPEERKVLNGITHPEVRHAILLKILMNYLKFHAMCILDVPL 120
DG++NRA LG +F + +R +LN I HP VR +L ++L Y++ +++ ILDVPL
Sbjct: 61 ---EDGTLNRAKLGQAVFQDAGKRSLLNSIIHPAVRLEMLKELLRCYVRGYSIVILDVPL 117
Query: 121 LFEANLDIICGITVCVVCDRDLQLQRLMERNPELTEELALARIEAQMSMYDRISRSDYLI 180
LFEA + IC T+CV CD+ +Q QRL+ RNPELT E A R++AQM + + +D +I
Sbjct: 118 LFEAKMQFICWKTICVSCDKSIQKQRLLARNPELTAEDAENRVQAQMPLELKCQLADIVI 177
Query: 181 DNNGDIKELFGNIDGLLTYIKPS 203
+NN D++ L+ NI +L I PS
Sbjct: 178 ENNSDLETLYENIHNVLPLITPS 200
>CE23950 [H] KOG3220 Similar to bacterial dephospho-CoA kinase
Length = 237
Score = 141 bits (356), Expect = 9e-34
Identities = 84/233 (36%), Positives = 134/233 (57%), Gaps = 10/233 (4%)
Query: 1 MLIIGLTGGIACGKSTVSSRLKTHYRIPVIDADAIARRILDPGQNAYKRVIRYFSGKVSN 60
ML++GL+GG+A GKSTVSS + H +P+IDAD +AR+++ PG + Y R+ + F + +
Sbjct: 11 MLVVGLSGGVATGKSTVSSVFRAH-GVPIIDADQVARQVVVPGTSTYNRLRKEFGDEYFD 69
Query: 61 LVLADGSINRAALGAYIFANPEERKVLNGITHPEVRHAILLKILMNYLKFHAMCILDVPL 120
G + R LG IF+NPE+RK LNGITHP +R + + L + + D PL
Sbjct: 70 DEHG-GVLRRDKLGKLIFSNPEKRKALNGITHPAIRWEMFKQFLTLLITGTKYIVFDTPL 128
Query: 121 LFEANLDIICGITVCVVCDRDLQLQRLMERNPELTEELALARIEAQMSMYDRISRSDYLI 180
LFE+ D G T+ V CD + +++R++ R+ ++ A +RI AQM + ++ R+ +I
Sbjct: 129 LFESGYDKWIGTTIVVWCDFEQEVERMVTRD-NISRADAESRIHAQMDIEEKKKRAKIVI 187
Query: 181 DNNGDIKELFGNIDGLLTYIKPSAITVWLEYFPPYGFVAALSVI---FSRYLK 230
DNNG+I EL + ++ + S W Y F L V+ F +Y++
Sbjct: 188 DNNGNIDELREKVKHVIAQLDKS----WKPYIFRVAFGIILGVVPYYFFKYIR 236
>7298862 [H] KOG3220 Similar to bacterial dephospho-CoA kinase
Length = 236
Score = 141 bits (356), Expect = 9e-34
Identities = 84/190 (44%), Positives = 118/190 (61%), Gaps = 8/190 (4%)
Query: 1 MLIIGLTGGIACGKSTVSSRLKTHYRIPVIDADAIARRILDPGQNAYKRVIRYFSGKVSN 60
M I+ +TGGIA GKST+S ++ IPVIDAD IAR I++PGQ ++++ F +V
Sbjct: 1 MFIVAVTGGIATGKSTIS-KVFERQGIPVIDADKIAREIVEPGQPCWRQIREVFGDEV-- 57
Query: 61 LVLADGSINRAALGAYIFANPEERKVLNGITHPEVRHAILLKILMNYLKFHAMCILDVPL 120
+L INRA LG IF + E R LN ITHP + I ++ + HA +LD+PL
Sbjct: 58 -LLPSKEINRAVLGKMIFEDKELRGKLNKITHPTIHRKIFWQVCKLLVTGHAWIVLDLPL 116
Query: 121 LFEAN--LDIICGITVCVVCDRDLQLQRLMERNPELTEELALARIEAQMSMYDRISRSDY 178
LFE +D I I VCV CD D QL+RL+ RN EL+E A R+++QM + + +S +
Sbjct: 117 LFETGVLMDFIHKI-VCVTCDSDKQLERLIARN-ELSESEARHRVDSQMPLDKKCEKSHF 174
Query: 179 LIDNNGDIKE 188
+IDNNG ++E
Sbjct: 175 VIDNNGSVEE 184
>Hs19923601 [H] KOG3220 Similar to bacterial dephospho-CoA kinase
Length = 231
Score = 133 bits (335), Expect = 3e-31
Identities = 88/228 (38%), Positives = 129/228 (55%), Gaps = 12/228 (5%)
Query: 1 MLIIGLTGGIACGKSTVSSRLKTHYRIPVIDADAIARRILDPGQNAYKRVIRYFSGKVSN 60
M ++GLTGGIA GKS+V + VID D +AR ++ PG A++R++ F +V
Sbjct: 1 MFLVGLTGGIASGKSSVIQVFQ-QLGCAVIDVDVMARHVVQPGYPAHRRIVEVFGTEV-- 57
Query: 61 LVLADGSINRAALGAYIFANPEERKVLNGITHPEVRHAILLKILMNYLKFHAMCILDVPL 120
+L +G INR LG IF P+ R++L ITHPE+R ++ + +L+ + ILD+PL
Sbjct: 58 -LLENGDINRKVLGDLIFNQPDRRQLLIAITHPEIRKEMMKETFKYFLRGYRYVILDIPL 116
Query: 121 LFEA-NLDIICGITVCVVCDRDLQLQRLMERNPELTEELALARIEAQMSMYDRISRSDYL 179
LFE L TV V CDRD QL RLM RN L + A ARI AQ+ + D+ + ++
Sbjct: 117 LFETKKLLKYMKHTVVVYCDRDTQLARLMRRN-SLNRKDAEARINAQLPLTDKARMARHV 175
Query: 180 IDNNGDIKELFGNIDGLLTYIKPSAITVWLEYFP-PYGFVAALSVIFS 226
+DN+G+ + L T ++ S LEY P +G + L+ I S
Sbjct: 176 LDNSGEWSVTKRQVILLHTELERS-----LEYLPLRFGVLTGLAAIAS 218
>At2g27490 [H] KOG3220 Similar to bacterial dephospho-CoA kinase
Length = 232
Score = 132 bits (333), Expect = 4e-31
Identities = 79/212 (37%), Positives = 125/212 (58%), Gaps = 7/212 (3%)
Query: 1 MLIIGLTGGIACGKSTVSSRLKTHYRIPVIDADAIARRILDPGQNAYKRVIRYFSGKVSN 60
M I+GLTGGIA GKSTVS+ K IPV+DAD +AR +L G +KRV+ F ++
Sbjct: 1 MRIVGLTGGIASGKSTVSNLFKAS-GIPVVDADVVARDVLKKGSGGWKRVVAAFGEEI-- 57
Query: 61 LVLADGSINRAALGAYIFANPEERKVLNGITHPEVRHAILLKILMNYLKFHAMCILDVPL 120
+L G ++R LG +F++ +R++LN + P + I +IL + + ++D+PL
Sbjct: 58 -LLPSGEVDRPKLGQIVFSSDSKRQLLNKLMAPYISSGIFWEILKQWASGAKVIVVDIPL 116
Query: 121 LFEANLDIICGITVCVVCDRDLQLQRLMERNPELTEELALARIEAQMSMYDRISRSDYLI 180
LFE +D V V ++ QL+RLMER+ L+EE A R+ AQM + + S++D +I
Sbjct: 117 LFEVKMDKWTKPIVVVWVSQETQLKRLMERD-GLSEEDARNRVMAQMPLDSKRSKADVVI 175
Query: 181 DNNGDIKELFGNIDGLLTYIKPSAITVWLEYF 212
DNNG + +L + +L I+ W+E++
Sbjct: 176 DNNGSLDDLHQQFEKVLIEIRRP--LTWIEFW 205
>Hs22063771 [H] KOG3220 Similar to bacterial dephospho-CoA kinase
Length = 134
Score = 99.8 bits (247), Expect = 4e-21
Identities = 52/123 (42%), Positives = 77/123 (62%), Gaps = 4/123 (3%)
Query: 1 MLIIGLTGGIACGKSTVSSRLKTHYRIPVIDADAIARRILDPGQNAYKRVIRYFSGKVSN 60
M ++GLTGGIA GKS+V + VID D +AR ++ PG A++R++ F +V
Sbjct: 1 MFLVGLTGGIASGKSSVIQVFQ-QLGCAVIDVDVMARHVVQPGYPAHRRIVEVFGTEV-- 57
Query: 61 LVLADGSINRAALGAYIFANPEERKVLNGITHPEVRHAILLKILMNYLKFHAMCILDVPL 120
+L +G INR LG IF P+ R++LN ITHPE+R ++ + +L+ + ILD+PL
Sbjct: 58 -LLENGDINRKVLGDLIFNQPDRRQLLNAITHPEIRKEMMKETFKYFLRGYRYVILDIPL 116
Query: 121 LFE 123
LFE
Sbjct: 117 LFE 119
>HsM13376838_2 [H] KOG3220 Similar to bacterial dephospho-CoA kinase
Length = 225
Score = 75.5 bits (184), Expect = 8e-14
Identities = 52/180 (28%), Positives = 93/180 (50%), Gaps = 5/180 (2%)
Query: 1 MLIIGLTGGIACGKSTVSSRLKTHYRIPVIDADAIARRILDPGQNAYKRVIRYFSGKVSN 60
+ +IGLTG GKS+++ RLK VID+D + R PG AY+ V+ F ++
Sbjct: 19 LYVIGLTGISGSGKSSIAQRLKGLGAF-VIDSDHLGHRAYAPGGPAYQPVVEAFG---TD 74
Query: 61 LVLADGSINRAALGAYIFANPEERKVLNGITHPEVRHAILLKILMNYLKFHAMCILDVPL 120
++ DG INR LG+ +F N ++ K+L I P + ++ + +C++D +
Sbjct: 75 ILHKDGIINRKVLGSRVFGNKKQLKILTDIMWPIIAKLAREEMDRAVAEGKRVCVIDAAV 134
Query: 121 LFEANLDIICGITVCVVCDRDLQLQRLMERNPELTEELALARIEAQMSMYDRISRSDYLI 180
L EA + V ++R++ER+ L+E A +R+++QMS + +S ++
Sbjct: 135 LLEAGWQNLVHEVWTAVIPETEAVRRIVERD-GLSEAAAQSRLQSQMSGQQLVEQSHVVL 193
>Hs21489977_2 [H] KOG3220 Similar to bacterial dephospho-CoA kinase
Length = 225
Score = 75.5 bits (184), Expect = 8e-14
Identities = 52/180 (28%), Positives = 93/180 (50%), Gaps = 5/180 (2%)
Query: 1 MLIIGLTGGIACGKSTVSSRLKTHYRIPVIDADAIARRILDPGQNAYKRVIRYFSGKVSN 60
+ +IGLTG GKS+++ RLK VID+D + R PG AY+ V+ F ++
Sbjct: 19 LYVIGLTGISGSGKSSIAQRLKGLGAF-VIDSDHLGHRAYAPGGPAYQPVVEAFG---TD 74
Query: 61 LVLADGSINRAALGAYIFANPEERKVLNGITHPEVRHAILLKILMNYLKFHAMCILDVPL 120
++ DG INR LG+ +F N ++ K+L I P + ++ + +C++D +
Sbjct: 75 ILHKDGIINRKVLGSRVFGNKKQLKILTDIMWPIIAKLAREEMDRAVAEGKRVCVIDAAV 134
Query: 121 LFEANLDIICGITVCVVCDRDLQLQRLMERNPELTEELALARIEAQMSMYDRISRSDYLI 180
L EA + V ++R++ER+ L+E A +R+++QMS + +S ++
Sbjct: 135 LLEAGWQNLVHEVWTAVIPETEAVRRIVERD-GLSEAAAQSRLQSQMSGQQLVEQSHVVL 193
>CE28145_2 [H] KOG3220 Similar to bacterial dephospho-CoA kinase
Length = 263
Score = 52.4 bits (124), Expect = 7e-07
Identities = 27/78 (34%), Positives = 43/78 (54%), Gaps = 4/78 (5%)
Query: 3 IIGLTGGIACGKSTVSSRLKTHYRIPVIDADAIARRILDPGQNAYKRVIRYFSGKVSNLV 62
IIGL GGIA GKS + L+ + VID D +A + G + +++ +F G V
Sbjct: 21 IIGLAGGIASGKSHIGKYLRETHNFDVIDCDKLAHTCYERGSSLNRKIGEHFGGD----V 76
Query: 63 LADGSINRAALGAYIFAN 80
+ DG ++R LG +F++
Sbjct: 77 VVDGVVDRRKLGTIVFSD 94
Database: KOG eukaryal database 04/03
Posted date: Apr 14, 2003 1:07 PM
Number of letters in database: 30,389,216
Number of sequences in database: 60,738
Lambda K H
0.323 0.140 0.410
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 16,677,953
Number of Sequences: 60738
Number of extensions: 656695
Number of successful extensions: 1600
Number of sequences better than 1.0e-05: 10
Number of HSP's better than 0.0 without gapping: 7
Number of HSP's successfully gapped in prelim test: 3
Number of HSP's that attempted gapping in prelim test: 1572
Number of HSP's gapped (non-prelim): 10
length of query: 286
length of database: 30,389,216
effective HSP length: 105
effective length of query: 181
effective length of database: 24,011,726
effective search space: 4346122406
effective search space used: 4346122406
T: 11
A: 40
X1: 16 ( 7.5 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.9 bits)