ORF STATUS Function Best COG Functional category Pathways and functional systems
r_klactIV4634 good R KOG1337 General function prediction only N-methyltransferase
Only best alignment is shown:
BLASTP 2.2.3 [May-13-2002]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= r_klactIV4634 1583328 1581946 -461
(461 letters)
Database: KOG eukaryal database 04/03
60,738 sequences; 30,389,216 total letters
Searching..................................................done
Color Key for Alignment Scores: 
Score E
Sequences producing significant alignments: (bits) Value
YDR198c [R] KOG1337 N-methyltransferase 390 e-108
SPCC1223.04c [R] KOG1337 N-methyltransferase 73 8e-13
Hs8393013 [R] KOG1337 N-methyltransferase 61 4e-09
>YDR198c [R] KOG1337 N-methyltransferase
Length = 479
Score = 390 bits (1003), Expect = e-108
Identities = 206/470 (43%), Positives = 294/470 (61%), Gaps = 23/470 (4%)
Query: 10 DGKISRLLEWLNGSGKCYVNPKIEVFEDPLVGRGIRLGNGMLTKNEVLISIPSSHQLNFH 69
+GK+ LL WL S K Y+ P I + E P GRGI L +G + KN++++S+PSS QLNFH
Sbjct: 2 EGKVDVLLTWLKKSDKFYIAPNISICESPETGRGIVLSHGSIRKNDIIVSVPSSKQLNFH 61
Query: 70 TVLHWIAKFNKNI----FTNDNISIGEAATEL-FDDQGQEDPRIKAYGIFNQEELTDFNS 124
T+L+ I+KFNK + T D I + +++ DPR Y ++E L +S
Sbjct: 62 TILYHISKFNKELNIPGITIDRKPINYEDNIIEAENKAWADPRYGLYSELSKEFLLSLSS 121
Query: 125 FQLLCLFILAEWILLPNWSNGTITSWWKPFFDIFPTDDELRSIPTKWSLVRSDKNASILL 184
FQL+ +IL E LLP W++ I S WKPFFD++P+ +ELRSIP W+ + + S L+
Sbjct: 122 FQLVSFYILVENFLLPKWTHNEIYSDWKPFFDVWPSMEELRSIPAIWNCDPNSRYHS-LI 180
Query: 185 ESLPTASSEHEKRISQLLLADWNAVRGFLKKWTEEF-------THSTIGMDELFSHFVHI 237
E LP AS +H RIS L+ DW + + KW E + DELFS FVH+
Sbjct: 181 EYLPAASRKHMARISGLVREDWETISEVVLKWNEIYGSLSCTKNSDKFTSDELFSLFVHV 240
Query: 238 YFVINSRCLYMEIPLKT-DVKDYFTMVPFVDYLNHTNKASLHCYPEINKLKR----NVYG 292
YF+INSRCLY +IPLK D FT+VP+VD++NH ++ LHCYP+++ R N+ G
Sbjct: 241 YFIINSRCLYAKIPLKIEDSPSNFTLVPYVDFMNHICESDLHCYPQLSPQLRSEGENIIG 300
Query: 293 LGEFSIRVGNHQYEKAGEELFLNYGAHSNDFLLAEYGFTTLCNEWNFIDLTPEFCNMFTD 352
+G+F+IR G+H Y+ EELFLNYGAHSNDFLL EYGF N+WN++D++ E + D
Sbjct: 301 IGQFTIRCGDHLYDNINEELFLNYGAHSNDFLLNEYGFVVDGNKWNYLDISDEIIELIDD 360
Query: 353 PKD--ITFLDNLGYWKDFTISKGEISYRILVAVSLLVHRDHRKTERFALGYITEEYFEPE 410
K TFL YW D+TI++ +ISYRI VA++ V RD R+ +F GYI+E+YF+P+
Sbjct: 361 DKKEVKTFLLEHDYWGDYTINETDISYRIFVALNYYVTRDERRVRKFIEGYISEDYFKPK 420
Query: 411 TSSVINSLLRELEFQYMSKIDRISE---IQDDDWCKRNLLNLYEGYIEIL 457
SSV+ LL L +Y + ++E +++ C +NL+ +Y+GYI+IL
Sbjct: 421 ISSVLKELLVSLTAKYTKTLSELTEKVSNLENNLCLQNLITIYKGYIKIL 470
>SPCC1223.04c [R] KOG1337 N-methyltransferase
Length = 381
Score = 73.2 bits (178), Expect = 8e-13
Identities = 50/150 (33%), Positives = 71/150 (47%), Gaps = 16/150 (10%)
Query: 238 YFVINSRCLYMEIPLKTDVKDYFTMVPFVDYLNHTNKASLHCYPEINKLKRNVYGLGEFS 297
+ +N+RCLY + K + +D+ T+ P +Y NH+ PE N G +
Sbjct: 158 WLCVNTRCLYYDTGSK-NTEDHLTLAPIFEYFNHS--------PEAQTALINTRG----T 204
Query: 298 IRVGNHQYEKAGEELFLNYGAHSNDFLLAEYGFTTLCNEWNFIDLTPEFCNMFTDPKDIT 357
I + + + GE++FL YG H ND L EYGF L N N F D +
Sbjct: 205 ITIKSTRRIDKGEQIFLCYGPHGNDKLFTEYGF-CLSNNPNISIQLDRFIEF--DKWQQS 261
Query: 358 FLDNLGYWKDFTISKGEISYRILVAVSLLV 387
FL + GYW D+T S S+R LV V L+
Sbjct: 262 FLQDHGYWNDYTCSLHGASFRTLVGVRTLL 291
>Hs8393013 [R] KOG1337 N-methyltransferase
Length = 440
Score = 60.8 bits (146), Expect = 4e-09
Identities = 72/349 (20%), Positives = 144/349 (40%), Gaps = 48/349 (13%)
Query: 128 LCLFILAEWILLPNWSNGTITSWWKPFFDIFPTDDELRSIPTKWSLVRSDKNASILLESL 187
LC F+++E + S WKP+ +I P + + P + + ++L +SL
Sbjct: 110 LCTFLVSE-------KHAGHRSLWKPYLEILP---KAYTCP----VCLEPEVVNLLPKSL 155
Query: 188 PTASSEHEKRISQLLLADWNAVRGFLKKWTEEFTHSTIGMDELFSH--FVHIYFVINSRC 245
+ E + + + R F F + +D +FS+ + + +N+R
Sbjct: 156 KAKAEEQRAHVQEFFASS----RDFFSSLQPLFAEA---VDSIFSYSALLWAWCTVNTRA 208
Query: 246 LYMEIPLKTDVK---DYFTMVPFVDYLNHTNKASLHCYPEINKLKRNVYGLGEFSIRVGN 302
+Y+ + + D + P++D LNH+ + + + S +
Sbjct: 209 VYLRPRQRECLSAEPDTCALAPYLDLLNHSPHVQV----------KAAFNEETHSYEIRT 258
Query: 303 HQYEKAGEELFLNYGAHSNDFLLAEYGFTTLCNEWNFIDLTPEFCNMF---TD---PKDI 356
+ EE+F+ YG H N L EYGF ++ N + ++ E + TD K I
Sbjct: 259 TSRWRKHEEVFICYGPHDNQRLFLEYGFVSVHNPHACVYVSREILVKYLPSTDKQMDKKI 318
Query: 357 TFLDNLGYWKDFTISKGEISYRILVAVSLLVHRDHRKT--ERFALGYITEEYFEPETSSV 414
+ L + GY ++ T S+R+L A+ LL + T ++ LG + + E + +
Sbjct: 319 SILKDHGYIENLTFGWDGPSWRLLTALKLLCLEAEKFTCWKKVLLGEVISDTNEKTSLDI 378
Query: 415 INSLLRELEFQYMSKIDRISEIQDDDWCKRNLLNLYEGY----IEILRS 459
+ + + + ++S ++D+ N L L E ++ILR+
Sbjct: 379 AQKICYYFIEETNAVLQKVSHMKDEKEALINQLTLVESLWTEELKILRA 427
Database: KOG eukaryal database 04/03
Posted date: Apr 14, 2003 1:07 PM
Number of letters in database: 30,389,216
Number of sequences in database: 60,738
Lambda K H
0.322 0.140 0.432
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 29,872,745
Number of Sequences: 60738
Number of extensions: 1348271
Number of successful extensions: 2737
Number of sequences better than 1.0e-05: 3
Number of HSP's better than 0.0 without gapping: 1
Number of HSP's successfully gapped in prelim test: 2
Number of HSP's that attempted gapping in prelim test: 2727
Number of HSP's gapped (non-prelim): 3
length of query: 461
length of database: 30,389,216
effective HSP length: 110
effective length of query: 351
effective length of database: 23,708,036
effective search space: 8321520636
effective search space used: 8321520636
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.9 bits)