ORF STATUS Function Best COG Functional category Pathways and functional systems
r_klactIV4639 good T KOG3872 Signal transduction mechanisms FOG: FHA domain
Only best alignment is shown:
BLASTP 2.2.3 [May-13-2002]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= r_klactIV4639 1586047 1584647 -467
(467 letters)
Database: KOG eukaryal database 04/03
60,738 sequences; 30,389,216 total letters
Searching..................................................done
Color Key for Alignment Scores: 
Score E
Sequences producing significant alignments: (bits) Value
YDR200c [T] KOG3872 FOG: FHA domain 314 2e-85
YLR238w [T] KOG3872 FOG: FHA domain 306 3e-83
SPBC3H7.13 [T] KOG3872 FOG: FHA domain 71 4e-12
7289492_1 [T] KOG3872 FOG: FHA domain 60 9e-09
CE17187_1 [T] KOG3872 FOG: FHA domain 58 3e-08
>YDR200c [T] KOG3872 FOG: FHA domain
Length = 604
Score = 314 bits (805), Expect = 2e-85
Identities = 179/381 (46%), Positives = 232/381 (59%), Gaps = 33/381 (8%)
Query: 67 RNKYTHVLVLKSLNNTFETKFLVVPFKPSGLKLGRPVIGAXXXXXXXXXXXKADPQVKAD 126
R K+TH+++LKSLN TFETKFLVVPFKP GLKLGRPV + QV+ D
Sbjct: 155 RKKHTHIIILKSLNATFETKFLVVPFKPDGLKLGRPVTNSVNKNNSGSKRDLFSQQVRPD 214
Query: 127 NGNFDSRVLSRNHASLSCDAKTGKICIRDLKSSNGTFVNGSRIGQTDVEIKVGDVIDLGT 186
NGNFDSRVLSRNHA LSCD +GKI IRDLKSSNGTFVNG +I Q DVE+KVGD +DLGT
Sbjct: 215 NGNFDSRVLSRNHACLSCDPTSGKIYIRDLKSSNGTFVNGVKIRQNDVELKVGDTVDLGT 274
Query: 187 DIDTKLEHRKISALVEDISVIPLIG--ENDKLLVSNKRDFRSTPANNG------------ 232
DID+K EHRKISA VE+ISVIPL+ + LV K+D T NNG
Sbjct: 275 DIDSKFEHRKISAYVEEISVIPLMNTVSDPTNLVMKKQDH--TNKNNGNSTNINGIKIDR 332
Query: 233 ------IP-----------DPMVTITTAQKAAFEAAMFGDVNNLDLEDAVLGSETEILSG 275
IP + + TTAQ+AAFEAAMFGD+NN +L+D +LG ETE+LSG
Sbjct: 333 GHHNQHIPIRSHLKENYTEAGVTSATTAQRAAFEAAMFGDINNSELDDDILGPETEVLSG 392
Query: 276 IFINNSIGTSPNLINIIKTLVTDLTXXXXXXXXXXSIDNFIVNYITKLEYLSKMKMEQAD 335
IFINNS GTS NLIN+IKTL T+L+ S+ NF+ NY L++++K ++ +
Sbjct: 393 IFINNSAGTSINLINMIKTLTTELSLEKQELEKLHSMQNFMQNYTINLDFINKHMIDMNE 452
Query: 336 XXXXXXXXXXXXXXANQQAELTTIHNEEIQALKQENKKLNDSLKENNDLKNTKIKQLKSE 395
+ L ++++ +KQ+N K+ + + K+++L+SE
Sbjct: 453 KHLLKLSTALQKTLSENNDALLKESEDQLKEIKQQNNKVKSACSLKEKQNHEKLQELESE 512
Query: 396 VDELQTRLEVEIFKNTQLQQA 416
+ EL ++E E KN L Q+
Sbjct: 513 LRELNLQIEEERGKNLVLTQS 533
>YLR238w [T] KOG3872 FOG: FHA domain
Length = 478
Score = 306 bits (785), Expect = 3e-83
Identities = 168/355 (47%), Positives = 224/355 (62%), Gaps = 20/355 (5%)
Query: 67 RNKYTHVLVLKSLNNTFETKFLVVPFKPSGLKLGRPVIGAXXXXXXXXXXXK-----ADP 121
R KYT++LVL SLN TFE+K +V+PFKP GLKLGRPV + K
Sbjct: 69 RRKYTYILVLTSLNGTFESKHVVIPFKPDGLKLGRPVANSNSSSSSSLRGGKRVDSHTFS 128
Query: 122 QVKADNGNFDSRVLSRNHASLSCDAKTGKICIRDLKSSNGTFVNGSRIGQTDVEIKVGDV 181
QV++DNGNFDSRVLSRNHA LSCD TGK+ IRDLKSSNGTF+NG RIG DVEIKVGDV
Sbjct: 129 QVRSDNGNFDSRVLSRNHALLSCDPLTGKVYIRDLKSSNGTFINGQRIGSNDVEIKVGDV 188
Query: 182 IDLGTDIDTKLEHRKISALVEDISVIPLIGENDKLLVSNKRDFRSTPANNGIPDPMVTIT 241
IDLGTDIDTK+EHRKISA VE++ V PL+ S N D TIT
Sbjct: 189 IDLGTDIDTKIEHRKISATVEELFVQPLL--------------ESPIFENEDSDDCHTIT 234
Query: 242 TAQK-AAFEAAMFGDVNNLDLEDAVLGSETEILSGIFINNSIGTSPNLINIIKTLVTDLT 300
++ AA + ++GD NNL+LE+ +LGS+TEILSGIFINN IGTSP L NIIKTL ++
Sbjct: 235 EKEEAAAITSHIYGDSNNLELEEVILGSDTEILSGIFINNCIGTSPTLSNIIKTLAMEIP 294
Query: 301 XXXXXXXXXXSIDNFIVNYITKLEYLSKMKMEQADXXXXXXXXXXXXXXANQQAELTTIH 360
S++NF++NY T LEY +K+ +E+ D + + ++ +
Sbjct: 295 FSKCDNFKLQSMENFLINYTTHLEYTNKLLVEKNDQQLVKLQNGLRRKLSGKYEKIIEQN 354
Query: 361 NEEIQALKQENKKLNDSLKENNDLKNTKIKQLKSEVDELQTRLEVEIFKNTQLQQ 415
+++ L++++ S + N K K ++ E+++L+TRLEVE +KN+Q+ +
Sbjct: 355 RNQVKQLERDHMFFKKSFEVKKRRNNEKQKSMEREIEDLKTRLEVERYKNSQMMK 409
>SPBC3H7.13 [T] KOG3872 FOG: FHA domain
Length = 301
Score = 70.9 bits (172), Expect = 4e-12
Identities = 50/137 (36%), Positives = 71/137 (51%), Gaps = 24/137 (17%)
Query: 73 VLVLKSLNNTFETKFLVVPFKPSGL-KLGRPVIGAXXXXXXXXXXXKADPQVKADNGNFD 131
V+ L LN +F+TK LV+ PS + K+GR N F+
Sbjct: 4 VITLTPLNESFQTKKLVI--SPSTIYKIGR--------------HTNKSTSPSPSNLFFN 47
Query: 132 SRVLSRNHASLSCDAKTGKICIRDLKSSNGTFVNGSRIG-----QTDVEIKVGDVIDLGT 186
S+VLSR HA L D T + IRD+KSSNGTFVN +R+ ++ GD++D G
Sbjct: 48 SKVLSRQHAELWLDKDTLSVYIRDVKSSNGTFVNETRLSPENKPSAPCKLNSGDIVDFGV 107
Query: 187 DI--DTKLEHRKISALV 201
DI + ++ H+K+SA V
Sbjct: 108 DIYNEDEIVHQKVSAQV 124
>7289492_1 [T] KOG3872 FOG: FHA domain
Length = 327
Score = 59.7 bits (143), Expect = 9e-09
Identities = 30/67 (44%), Positives = 42/67 (61%), Gaps = 3/67 (4%)
Query: 124 KADNGN--FDSRVLSRNHASLSCDAKTGKICIRDLKSSNGTFVNGSRIGQTDVEIKVGDV 181
KA GN FD +VLSRNHA L GK ++D KSSNGTF+N +++G E+ GD+
Sbjct: 245 KAGEGNAIFDCKVLSRNHAILWY-TPDGKFWVKDTKSSNGTFINDNKLGSDPAELHYGDI 303
Query: 182 IDLGTDI 188
+ G ++
Sbjct: 304 VKFGVEV 310
>CE17187_1 [T] KOG3872 FOG: FHA domain
Length = 194
Score = 57.8 bits (138), Expect = 3e-08
Identities = 43/122 (35%), Positives = 62/122 (50%), Gaps = 24/122 (19%)
Query: 74 LVLKSLNNTFETKFLVVPFKPSGLKLGRPVIGAXXXXXXXXXXXKADPQVKADNGNFDSR 133
LV ++ FE + + V +K+GR V A Q A+N FD +
Sbjct: 8 LVATPKSHPFEERRIKVNGSNDPVKIGRAV---------------ARIQATAENAVFDCK 52
Query: 134 VLSRNHASLSCDAKTGKICIRDLKSSNGTFVNGSRIGQT----DVEIK---VGDVIDLGT 186
VLSRNHA L + G+ ++D KSSNGTFVN ++ QT D +++ GD+I LG
Sbjct: 53 VLSRNHAILWF--RDGEFWLKDTKSSNGTFVNNEKLQQTVSGRDTDVRRVFSGDIIQLGV 110
Query: 187 DI 188
+I
Sbjct: 111 EI 112
Database: KOG eukaryal database 04/03
Posted date: Apr 14, 2003 1:07 PM
Number of letters in database: 30,389,216
Number of sequences in database: 60,738
Lambda K H
0.310 0.129 0.341
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 20,716,763
Number of Sequences: 60738
Number of extensions: 762465
Number of successful extensions: 2811
Number of sequences better than 1.0e-05: 5
Number of HSP's better than 0.0 without gapping: 2
Number of HSP's successfully gapped in prelim test: 3
Number of HSP's that attempted gapping in prelim test: 2802
Number of HSP's gapped (non-prelim): 6
length of query: 467
length of database: 30,389,216
effective HSP length: 110
effective length of query: 357
effective length of database: 23,708,036
effective search space: 8463768852
effective search space used: 8463768852
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.8 bits)