ORF STATUS Function Best COG Functional category Pathways and functional systems
r_klactIV4697 good T KOG0789 Signal transduction mechanisms Protein tyrosine phosphatase
Only best alignment is shown:
BLASTP 2.2.3 [May-13-2002]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= r_klactIV4697 1605744 1605337 -136
(136 letters)
Database: KOG eukaryal database 04/03
60,738 sequences; 30,389,216 total letters
Searching..................................................done
Color Key for Alignment Scores: 
Score E
Sequences producing significant alignments: (bits) Value
YDL230w [T] KOG0789 Protein tyrosine phosphatase 128 2e-30
7292674 [T] KOG0791 Protein tyrosine phosphatase contains fn3 do... 67 9e-12
SPAC19D5.01 [T] KOG0789 Protein tyrosine phosphatase 65 3e-11
Hs4506295 [T] KOG0792 Protein tyrosine phosphatase PTPMEG contai... 65 3e-11
CE03335 [T] KOG0791 Protein tyrosine phosphatase contains fn3 do... 63 1e-10
CE24794 [T] KOG4228 Protein tyrosine phosphatase 62 3e-10
CE23603 [T] KOG0792 Protein tyrosine phosphatase PTPMEG contains... 62 3e-10
CE17578 [T] KOG0792 Protein tyrosine phosphatase PTPMEG contains... 62 3e-10
7294551 [T] KOG4228 Protein tyrosine phosphatase 62 3e-10
Hs4506291 [T] KOG0789 Protein tyrosine phosphatase 61 4e-10
Hs4506289 [T] KOG0789 Protein tyrosine phosphatase 61 4e-10
Hs18104982 [T] KOG0789 Protein tyrosine phosphatase 61 4e-10
Hs18104980 [T] KOG0789 Protein tyrosine phosphatase 61 4e-10
Hs5453992 [T] KOG0792 Protein tyrosine phosphatase PTPMEG contai... 61 5e-10
Hs18375650 [T] KOG0792 Protein tyrosine phosphatase PTPMEG conta... 61 5e-10
Hs18375648 [T] KOG0792 Protein tyrosine phosphatase PTPMEG conta... 61 5e-10
Hs18375646 [T] KOG0792 Protein tyrosine phosphatase PTPMEG conta... 61 5e-10
Hs18104986 [T] KOG0792 Protein tyrosine phosphatase PTPMEG conta... 61 5e-10
Hs4506323 [T] KOG0791 Protein tyrosine phosphatase contains fn3 ... 60 8e-10
Hs13677218 [T] KOG0791 Protein tyrosine phosphatase contains fn3... 60 8e-10
Hs13677216 [T] KOG0791 Protein tyrosine phosphatase contains fn3... 60 8e-10
Hs13677214 [T] KOG0791 Protein tyrosine phosphatase contains fn3... 60 8e-10
CE06093 [T] KOG4228 Protein tyrosine phosphatase 60 1e-09
Hs19743929 [T] KOG4228 Protein tyrosine phosphatase 59 2e-09
Hs19743927 [T] KOG4228 Protein tyrosine phosphatase 59 2e-09
Hs19743925 [T] KOG4228 Protein tyrosine phosphatase 59 2e-09
Hs19743923 [T] KOG4228 Protein tyrosine phosphatase 59 2e-09
Hs19743921 [T] KOG4228 Protein tyrosine phosphatase 59 2e-09
Hs19743919 [T] KOG4228 Protein tyrosine phosphatase 59 2e-09
At1g71860 [T] KOG0789 Protein tyrosine phosphatase 59 2e-09
Hs4506311 [T] KOG4228 Protein tyrosine phosphatase 58 3e-09
Hs18860896 [T] KOG4228 Protein tyrosine phosphatase 58 3e-09
Hs18860898_2 [T] KOG0789 Protein tyrosine phosphatase 58 3e-09
SPAC11E3.09 [T] KOG0791 Protein tyrosine phosphatase contains fn... 58 4e-09
Hs4885567 [T] KOG0792 Protein tyrosine phosphatase PTPMEG contai... 58 4e-09
Hs4506313 [T] KOG0791 Protein tyrosine phosphatase contains fn3 ... 58 4e-09
Hs4506309 [T] KOG4228 Protein tyrosine phosphatase 57 5e-09
Hs18860894 [T] KOG4228 Protein tyrosine phosphatase 57 5e-09
Hs18860892 [T] KOG4228 Protein tyrosine phosphatase 57 5e-09
Hs18860890 [T] KOG4228 Protein tyrosine phosphatase 57 5e-09
7290546 [T] KOG0791 Protein tyrosine phosphatase contains fn3 do... 57 7e-09
7291964 [T] KOG0792 Protein tyrosine phosphatase PTPMEG contains... 57 9e-09
Hs18860904 [T] KOG4228 Protein tyrosine phosphatase 56 1e-08
Hs18860902 [T] KOG4228 Protein tyrosine phosphatase 56 1e-08
CE29409 [T] KOG4228 Protein tyrosine phosphatase 56 2e-08
CE29408 [T] KOG4228 Protein tyrosine phosphatase 56 2e-08
CE26369 [T] KOG4228 Protein tyrosine phosphatase 56 2e-08
Hs5902032 [T] KOG0792 Protein tyrosine phosphatase PTPMEG contai... 55 2e-08
SPAC26F1.10c [T] KOG0789 Protein tyrosine phosphatase 55 3e-08
Hs4506321 [T] KOG0793 Protein tyrosine phosphatase 55 3e-08
Hs22053842 [T] KOG0789 Protein tyrosine phosphatase 54 6e-08
CE15903 [T] KOG0789 Protein tyrosine phosphatase 54 6e-08
CE11200 [T] KOG0789 Protein tyrosine phosphatase 54 6e-08
7301780 [T] KOG0789 Protein tyrosine phosphatase 54 6e-08
Hs18491010 [T] KOG0791 Protein tyrosine phosphatase contains fn3... 54 8e-08
Hs18860900 [T] KOG0791 Protein tyrosine phosphatase contains fn3... 53 1e-07
Hs22052020_2 [T] KOG0789 Protein tyrosine phosphatase 52 2e-07
Hs4506303 [T] KOG4228 Protein tyrosine phosphatase 52 2e-07
Hs18450369 [T] KOG4228 Protein tyrosine phosphatase 52 2e-07
Hs18104993 [T] KOG0790 Protein tyrosine phosphatase Corkscrew an... 52 2e-07
Hs18104991 [T] KOG0790 Protein tyrosine phosphatase Corkscrew an... 52 2e-07
Hs18104989 [T] KOG0790 Protein tyrosine phosphatase Corkscrew an... 52 2e-07
Hs5729993 [T] KOG4228 Protein tyrosine phosphatase 51 4e-07
Hs18860859 [T] KOG4228 Protein tyrosine phosphatase 51 4e-07
Hs18641364 [T] KOG4228 Protein tyrosine phosphatase 51 4e-07
Hs18641362 [T] KOG4228 Protein tyrosine phosphatase 51 4e-07
Hs18641347 [T] KOG4228 Protein tyrosine phosphatase 51 4e-07
Hs7706280 [T] KOG0789 Protein tyrosine phosphatase 51 5e-07
Hs19743931 [T] KOG4228 Protein tyrosine phosphatase 51 5e-07
Hs18375644 [T] KOG0790 Protein tyrosine phosphatase Corkscrew an... 51 5e-07
Hs18375642 [T] KOG0790 Protein tyrosine phosphatase Corkscrew an... 51 5e-07
CE10628 [T] KOG0789 Protein tyrosine phosphatase 51 5e-07
Hs19743914 [T] KOG0793 Protein tyrosine phosphatase 50 7e-07
Hs19743912 [T] KOG0793 Protein tyrosine phosphatase 50 7e-07
Hs18375655 [T] KOG0789 Protein tyrosine phosphatase 50 7e-07
Hs15619018 [T] KOG0789 Protein tyrosine phosphatase 50 7e-07
Hs11386149 [T] KOG0793 Protein tyrosine phosphatase 50 7e-07
Hs4506329 [T] KOG0789 Protein tyrosine phosphatase 50 9e-07
CE02705 [T] KOG0790 Protein tyrosine phosphatase Corkscrew and r... 50 9e-07
Hs18375652 [T] KOG0789 Protein tyrosine phosphatase 50 1e-06
7292074 [T] KOG0789 Protein tyrosine phosphatase 50 1e-06
Hs14736297_2 [T] KOG0789 Protein tyrosine phosphatase 50 1e-06
CE27280 [T] KOG0789 Protein tyrosine phosphatase 49 2e-06
Hs18375660 [T] KOG0789 Protein tyrosine phosphatase 47 6e-06
Hs18375658 [T] KOG0789 Protein tyrosine phosphatase 47 6e-06
Hs4506325 [T] KOG0789 Protein tyrosine phosphatase 47 9e-06
Hs19743917 [T] KOG0789 Protein tyrosine phosphatase 47 9e-06
>YDL230w [T] KOG0789 Protein tyrosine phosphatase
Length = 335
Score = 128 bits (321), Expect = 2e-30
Identities = 59/118 (50%), Positives = 76/118 (64%)
Query: 13 PKYLDQDDRDLLLKFRYIRQQEDARIRDGALHPRDSEWTFGVSDAKCNMTRNRYTNIKTY 72
P Y+ Q D DLL KF++I+ QED R+R+ +S W+ GVS N RNRY NI Y
Sbjct: 5 PWYIRQRDTDLLGKFKFIQNQEDGRLREATNGTVNSRWSLGVSIEPRNDARNRYVNIMPY 64
Query: 73 EKTRIKLKVVQGNDYINASDIRLQIEGQSKAPSHFIACQGPLPNTWPQFWQMVYQQCP 130
E+ R+ LK + GNDYINAS +++ + GQS P ++IA QGP TW QFWQM Y CP
Sbjct: 65 ERNRVHLKTLSGNDYINASYVKVNVPGQSIEPGYYIATQGPTRKTWDQFWQMCYHNCP 122
>7292674 [T] KOG0791 Protein tyrosine phosphatase contains fn3 domain
Length = 1647
Score = 66.6 bits (161), Expect = 9e-12
Identities = 46/141 (32%), Positives = 73/141 (51%), Gaps = 19/141 (13%)
Query: 5 KTSDRMSRPKYLDQDDRDLLLK-----FRYIRQQEDARIRDGALH----PRDSEWTFGVS 55
+ +D MS P + + +R +L+K +R + D R + RD TF +
Sbjct: 1250 RANDNMSLPDSVIEQNRPILIKNFAEHYRLMSADSDFRFSEEFEELKHVGRDQPCTF--A 1307
Query: 56 DAKCNMTRNRYTNIKTYEKTRIKLKVV---QGNDYINASDIRLQIEGQSKAPSHFIACQG 112
D CN +NR+TNI Y+ +R KL+ V +G+DYINA+ + G + +P FI QG
Sbjct: 1308 DLPCNRPKNRFTNILPYDHSRFKLQPVDDDEGSDYINAN----YVPGHN-SPREFIVTQG 1362
Query: 113 PLPNTWPQFWQMVYQQCPKKI 133
PL +T FW+M ++ + I
Sbjct: 1363 PLHSTRDDFWRMCWESNSRAI 1383
>SPAC19D5.01 [T] KOG0789 Protein tyrosine phosphatase
Length = 711
Score = 65.1 bits (157), Expect = 3e-11
Identities = 40/102 (39%), Positives = 59/102 (57%), Gaps = 9/102 (8%)
Query: 27 FRYIRQQEDARIRDGALHPRDSEWTFGVSDAKCNMTR-NRYTNIKTYEKTRIKLKVVQG- 84
+++ R +E R A + S+W S +++R NRYT+I Y+KTR++L V +G
Sbjct: 424 YKFKRLEEMEMTRSLAFNDSKSDWCCLASSRSTSISRKNRYTDIVPYDKTRVRLAVPKGC 483
Query: 85 NDYINASDIRLQIEGQSKAPSHFIACQGPLPNTWPQFWQMVY 126
+DYINAS I + G K +IACQ P P T FW+MV+
Sbjct: 484 SDYINASHIDV---GNKK----YIACQAPKPGTLLDFWEMVW 518
>Hs4506295 [T] KOG0792 Protein tyrosine phosphatase PTPMEG contains FERM
domain
Length = 926
Score = 65.1 bits (157), Expect = 3e-11
Identities = 34/70 (48%), Positives = 48/70 (68%), Gaps = 5/70 (7%)
Query: 60 NMTRNRYTNIKTYEKTRIKLKVVQGN-DYINASDIRLQIEGQSKAPSHFIACQGPLPNTW 118
N+++NRY +I Y+ TR+ LK GN DYINA+ I ++I S + +IACQGPLP+T
Sbjct: 679 NISKNRYRDISPYDATRVILK---GNEDYINANYINMEIPSSSII-NQYIACQGPLPHTC 734
Query: 119 PQFWQMVYQQ 128
FWQM ++Q
Sbjct: 735 TDFWQMTWEQ 744
>CE03335 [T] KOG0791 Protein tyrosine phosphatase contains fn3 domain
Length = 1367
Score = 63.2 bits (152), Expect = 1e-10
Identities = 36/80 (45%), Positives = 48/80 (60%), Gaps = 9/80 (11%)
Query: 55 SDAKCNMTRNRYTNIKTYEKTRIKLKV---VQGNDYINASDIRLQIEGQSKAPSHFIACQ 111
S+ N +NR+TNI +Y+ +R+KL ++G DYINA+ + G S FIA Q
Sbjct: 1091 SELPINRPKNRFTNIPSYDHSRVKLSNPNNIEGGDYINAN----YVPGFSSR-REFIAAQ 1145
Query: 112 GPLPNTWPQFWQMVY-QQCP 130
GPLP T FWQM + QQCP
Sbjct: 1146 GPLPTTRDHFWQMTWEQQCP 1165
>CE24794 [T] KOG4228 Protein tyrosine phosphatase
Length = 2234
Score = 61.6 bits (148), Expect = 3e-10
Identities = 33/82 (40%), Positives = 50/82 (60%), Gaps = 8/82 (9%)
Query: 50 WTFGVSDAKCNMTRNRYTNIKTYEKTRIKLKVVQGN---DYINASDIRLQIEGQSKAPSH 106
+T+ S A N +NRY N+ Y+ +R+ L V+G DYINA+ ++G K P
Sbjct: 1694 FTWEHSSADMNKHKNRYANVAAYDHSRVVLSNVEGYPGMDYINAN----YVDGYDK-PRS 1748
Query: 107 FIACQGPLPNTWPQFWQMVYQQ 128
+IA QGPLP T+ FW+MV+++
Sbjct: 1749 YIATQGPLPETFSDFWRMVWEE 1770
>CE23603 [T] KOG0792 Protein tyrosine phosphatase PTPMEG contains FERM
domain
Length = 624
Score = 61.6 bits (148), Expect = 3e-10
Identities = 28/69 (40%), Positives = 44/69 (63%), Gaps = 1/69 (1%)
Query: 60 NMTRNRYTNIKTYEKTRIKLKVVQGNDYINASDIRLQIEGQSKAPSHFIACQGPLPNTWP 119
N+ +NRY ++ Y+ TR+ L+ DYINA+ + ++I S + +IACQGPL +T
Sbjct: 375 NLAKNRYRDVCPYDDTRVTLQASPSGDYINANYVNMEIP-SSGIVNRYIACQGPLAHTSS 433
Query: 120 QFWQMVYQQ 128
FW MV++Q
Sbjct: 434 DFWVMVWEQ 442
>CE17578 [T] KOG0792 Protein tyrosine phosphatase PTPMEG contains FERM
domain
Length = 1026
Score = 61.6 bits (148), Expect = 3e-10
Identities = 28/69 (40%), Positives = 44/69 (63%), Gaps = 1/69 (1%)
Query: 60 NMTRNRYTNIKTYEKTRIKLKVVQGNDYINASDIRLQIEGQSKAPSHFIACQGPLPNTWP 119
N+ +NRY ++ Y+ TR+ L+ DYINA+ + ++I S + +IACQGPL +T
Sbjct: 777 NLAKNRYRDVCPYDDTRVTLQASPSGDYINANYVNMEIP-SSGIVNRYIACQGPLAHTSS 835
Query: 120 QFWQMVYQQ 128
FW MV++Q
Sbjct: 836 DFWVMVWEQ 844
>7294551 [T] KOG4228 Protein tyrosine phosphatase
Length = 1428
Score = 61.6 bits (148), Expect = 3e-10
Identities = 35/86 (40%), Positives = 50/86 (57%), Gaps = 8/86 (9%)
Query: 46 RDSEWTFGVSDAKCNMTRNRYTNIKTYEKTRIKLKVVQG---NDYINASDIRLQIEGQSK 102
R S+ T SD K N +NRY +IK Y++TR+KL V+ G DYINA+ + K
Sbjct: 869 RFSDRTTKNSDLKENACKNRYPDIKAYDQTRVKLAVINGLQTTDYINANFVI-----GYK 923
Query: 103 APSHFIACQGPLPNTWPQFWQMVYQQ 128
FI QGP+ +T FW+M+++Q
Sbjct: 924 ERKKFICAQGPMESTIDDFWRMIWEQ 949
>Hs4506291 [T] KOG0789 Protein tyrosine phosphatase
Length = 415
Score = 61.2 bits (147), Expect = 4e-10
Identities = 32/74 (43%), Positives = 46/74 (61%), Gaps = 6/74 (8%)
Query: 60 NMTRNRYTNIKTYEKTRIKLKVVQGNDYINASDIRLQIEGQSKAPSHFIACQGPLPNTWP 119
N RNRY ++ Y+ +R+KL+ + NDYINAS + ++ +A +I QGPLPNT
Sbjct: 42 NRNRNRYRDVSPYDHSRVKLQNAE-NDYINASLVDIE-----EAQRSYILTQGPLPNTCC 95
Query: 120 QFWQMVYQQCPKKI 133
FW MV+QQ K +
Sbjct: 96 HFWLMVWQQKTKAV 109
>Hs4506289 [T] KOG0789 Protein tyrosine phosphatase
Length = 435
Score = 61.2 bits (147), Expect = 4e-10
Identities = 33/81 (40%), Positives = 50/81 (60%), Gaps = 6/81 (7%)
Query: 48 SEWTFGVSDAKCNMTRNRYTNIKTYEKTRIKLKVVQGNDYINASDIRLQIEGQSKAPSHF 107
S++ V+ N RNRY ++ ++ +RIKL + NDYINAS I+++ +A +
Sbjct: 28 SDFPCRVAKLPKNKNRNRYRDVSPFDHSRIKLHQ-EDNDYINASLIKME-----EAQRSY 81
Query: 108 IACQGPLPNTWPQFWQMVYQQ 128
I QGPLPNT FW+MV++Q
Sbjct: 82 ILTQGPLPNTCGHFWEMVWEQ 102
>Hs18104982 [T] KOG0789 Protein tyrosine phosphatase
Length = 353
Score = 61.2 bits (147), Expect = 4e-10
Identities = 32/74 (43%), Positives = 46/74 (61%), Gaps = 6/74 (8%)
Query: 60 NMTRNRYTNIKTYEKTRIKLKVVQGNDYINASDIRLQIEGQSKAPSHFIACQGPLPNTWP 119
N RNRY ++ Y+ +R+KL+ + NDYINAS + ++ +A +I QGPLPNT
Sbjct: 42 NRNRNRYRDVSPYDHSRVKLQNAE-NDYINASLVDIE-----EAQRSYILTQGPLPNTCC 95
Query: 120 QFWQMVYQQCPKKI 133
FW MV+QQ K +
Sbjct: 96 HFWLMVWQQKTKAV 109
>Hs18104980 [T] KOG0789 Protein tyrosine phosphatase
Length = 387
Score = 61.2 bits (147), Expect = 4e-10
Identities = 32/74 (43%), Positives = 46/74 (61%), Gaps = 6/74 (8%)
Query: 60 NMTRNRYTNIKTYEKTRIKLKVVQGNDYINASDIRLQIEGQSKAPSHFIACQGPLPNTWP 119
N RNRY ++ Y+ +R+KL+ + NDYINAS + ++ +A +I QGPLPNT
Sbjct: 42 NRNRNRYRDVSPYDHSRVKLQNAE-NDYINASLVDIE-----EAQRSYILTQGPLPNTCC 95
Query: 120 QFWQMVYQQCPKKI 133
FW MV+QQ K +
Sbjct: 96 HFWLMVWQQKTKAV 109
>Hs5453992 [T] KOG0792 Protein tyrosine phosphatase PTPMEG contains FERM domain
Length = 2466
Score = 60.8 bits (146), Expect = 5e-10
Identities = 33/75 (44%), Positives = 44/75 (58%), Gaps = 5/75 (6%)
Query: 54 VSDAKCNMTRNRYTNIKTYEKTRIKLKVVQGNDYINASDIRLQIEGQSKAPSHFIACQGP 113
+ K N +NRY NI Y+ TR+ L G YINAS I++ + K +IACQGP
Sbjct: 2212 IGQTKENRRKNRYKNILPYDATRVPLGDEGG--YINASFIKIPV---GKEEFVYIACQGP 2266
Query: 114 LPNTWPQFWQMVYQQ 128
LP T FWQM+++Q
Sbjct: 2267 LPTTVGDFWQMIWEQ 2281
>Hs18375650 [T] KOG0792 Protein tyrosine phosphatase PTPMEG contains FERM domain
Length = 2490
Score = 60.8 bits (146), Expect = 5e-10
Identities = 33/75 (44%), Positives = 44/75 (58%), Gaps = 5/75 (6%)
Query: 54 VSDAKCNMTRNRYTNIKTYEKTRIKLKVVQGNDYINASDIRLQIEGQSKAPSHFIACQGP 113
+ K N +NRY NI Y+ TR+ L G YINAS I++ + K +IACQGP
Sbjct: 2236 IGQTKENRRKNRYKNILPYDATRVPLGDEGG--YINASFIKIPV---GKEEFVYIACQGP 2290
Query: 114 LPNTWPQFWQMVYQQ 128
LP T FWQM+++Q
Sbjct: 2291 LPTTVGDFWQMIWEQ 2305
>Hs18375648 [T] KOG0792 Protein tyrosine phosphatase PTPMEG contains FERM domain
Length = 2294
Score = 60.8 bits (146), Expect = 5e-10
Identities = 33/75 (44%), Positives = 44/75 (58%), Gaps = 5/75 (6%)
Query: 54 VSDAKCNMTRNRYTNIKTYEKTRIKLKVVQGNDYINASDIRLQIEGQSKAPSHFIACQGP 113
+ K N +NRY NI Y+ TR+ L G YINAS I++ + K +IACQGP
Sbjct: 2040 IGQTKENRRKNRYKNILPYDATRVPLGDEGG--YINASFIKIPV---GKEEFVYIACQGP 2094
Query: 114 LPNTWPQFWQMVYQQ 128
LP T FWQM+++Q
Sbjct: 2095 LPTTVGDFWQMIWEQ 2109
>Hs18375646 [T] KOG0792 Protein tyrosine phosphatase PTPMEG contains FERM domain
Length = 2485
Score = 60.8 bits (146), Expect = 5e-10
Identities = 33/75 (44%), Positives = 44/75 (58%), Gaps = 5/75 (6%)
Query: 54 VSDAKCNMTRNRYTNIKTYEKTRIKLKVVQGNDYINASDIRLQIEGQSKAPSHFIACQGP 113
+ K N +NRY NI Y+ TR+ L G YINAS I++ + K +IACQGP
Sbjct: 2231 IGQTKENRRKNRYKNILPYDATRVPLGDEGG--YINASFIKIPV---GKEEFVYIACQGP 2285
Query: 114 LPNTWPQFWQMVYQQ 128
LP T FWQM+++Q
Sbjct: 2286 LPTTVGDFWQMIWEQ 2300
>Hs18104986 [T] KOG0792 Protein tyrosine phosphatase PTPMEG contains FERM
domain
Length = 913
Score = 60.8 bits (146), Expect = 5e-10
Identities = 32/70 (45%), Positives = 47/70 (66%), Gaps = 5/70 (7%)
Query: 60 NMTRNRYTNIKTYEKTRIKLKVVQGN-DYINASDIRLQIEGQSKAPSHFIACQGPLPNTW 118
N+ +NRY ++ Y+ TR+ L QGN DYINAS + ++I + + +IA QGPLP+T
Sbjct: 670 NLDKNRYKDVLPYDTTRVLL---QGNEDYINASYVNMEIPAANLV-NKYIATQGPLPHTC 725
Query: 119 PQFWQMVYQQ 128
QFWQ+V+ Q
Sbjct: 726 AQFWQVVWDQ 735
>Hs4506323 [T] KOG0791 Protein tyrosine phosphatase contains fn3 domain
Length = 1188
Score = 60.1 bits (144), Expect = 8e-10
Identities = 42/113 (37%), Positives = 60/113 (52%), Gaps = 27/113 (23%)
Query: 35 DARIRDGALHPRDSEWTFGV----------------SDAKCNMTRNRYTNIKTYEKTRIK 78
DA I+D A +DS++ F + +D N +NRYTNI Y+ +R++
Sbjct: 896 DAYIKDMA---KDSDYKFSLQFEELKLIGLDIPHFAADLPLNRCKNRYTNILPYDFSRVR 952
Query: 79 LKVV---QGNDYINASDIRLQIEGQSKAPSHFIACQGPLPNTWPQFWQMVYQQ 128
L + +G DYINA+ I G + +P +IA QGPLP T FW+MV QQ
Sbjct: 953 LVSMNEEEGADYINAN----YIPGYN-SPQEYIATQGPLPETRNDFWKMVLQQ 1000
>Hs13677218 [T] KOG0791 Protein tyrosine phosphatase contains fn3 domain
Length = 405
Score = 60.1 bits (144), Expect = 8e-10
Identities = 42/113 (37%), Positives = 60/113 (52%), Gaps = 27/113 (23%)
Query: 35 DARIRDGALHPRDSEWTFGV----------------SDAKCNMTRNRYTNIKTYEKTRIK 78
DA I+D A +DS++ F + +D N +NRYTNI Y+ +R++
Sbjct: 113 DAYIKDMA---KDSDYKFSLQFEELKLIGLDIPHFAADLPLNRCKNRYTNILPYDFSRVR 169
Query: 79 LKVV---QGNDYINASDIRLQIEGQSKAPSHFIACQGPLPNTWPQFWQMVYQQ 128
L + +G DYINA+ I G + +P +IA QGPLP T FW+MV QQ
Sbjct: 170 LVSMNEEEGADYINAN----YIPGYN-SPQEYIATQGPLPETRNDFWKMVLQQ 217
>Hs13677216 [T] KOG0791 Protein tyrosine phosphatase contains fn3 domain
Length = 377
Score = 60.1 bits (144), Expect = 8e-10
Identities = 42/113 (37%), Positives = 60/113 (52%), Gaps = 27/113 (23%)
Query: 35 DARIRDGALHPRDSEWTFGV----------------SDAKCNMTRNRYTNIKTYEKTRIK 78
DA I+D A +DS++ F + +D N +NRYTNI Y+ +R++
Sbjct: 85 DAYIKDMA---KDSDYKFSLQFEELKLIGLDIPHFAADLPLNRCKNRYTNILPYDFSRVR 141
Query: 79 LKVV---QGNDYINASDIRLQIEGQSKAPSHFIACQGPLPNTWPQFWQMVYQQ 128
L + +G DYINA+ I G + +P +IA QGPLP T FW+MV QQ
Sbjct: 142 LVSMNEEEGADYINAN----YIPGYN-SPQEYIATQGPLPETRNDFWKMVLQQ 189
>Hs13677214 [T] KOG0791 Protein tyrosine phosphatase contains fn3 domain
Length = 1216
Score = 60.1 bits (144), Expect = 8e-10
Identities = 42/113 (37%), Positives = 60/113 (52%), Gaps = 27/113 (23%)
Query: 35 DARIRDGALHPRDSEWTFGV----------------SDAKCNMTRNRYTNIKTYEKTRIK 78
DA I+D A +DS++ F + +D N +NRYTNI Y+ +R++
Sbjct: 924 DAYIKDMA---KDSDYKFSLQFEELKLIGLDIPHFAADLPLNRCKNRYTNILPYDFSRVR 980
Query: 79 LKVV---QGNDYINASDIRLQIEGQSKAPSHFIACQGPLPNTWPQFWQMVYQQ 128
L + +G DYINA+ I G + +P +IA QGPLP T FW+MV QQ
Sbjct: 981 LVSMNEEEGADYINAN----YIPGYN-SPQEYIATQGPLPETRNDFWKMVLQQ 1028
>CE06093 [T] KOG4228 Protein tyrosine phosphatase
Length = 1156
Score = 59.7 bits (143), Expect = 1e-09
Identities = 39/114 (34%), Positives = 59/114 (51%), Gaps = 9/114 (7%)
Query: 15 YLDQDDRDLLLKFRYIRQQEDARIRDGALHPRDSEWTFGVSDAKCNMTRNRYTNIKTYEK 74
Y++ +R+ LKF+ Q + + + DS + SD N +NRY NI E
Sbjct: 646 YVEDLNRNDSLKFK--TQFQILESQTSGIDSVDSGESNSSSDE--NSQKNRYNNIGAIEA 701
Query: 75 TRIKLKVVQGNDYINASDIRLQIEGQSKAPSHFIACQGPLPNTWPQFWQMVYQQ 128
TRI+L GNDYINA+ + + +IA Q PLP+T+ FW M++Q+
Sbjct: 702 TRIRLNSPTGNDYINANYV-----DSCNERNAYIATQAPLPSTFSDFWSMIWQE 750
>Hs19743929 [T] KOG4228 Protein tyrosine phosphatase
Length = 1444
Score = 58.9 bits (141), Expect = 2e-09
Identities = 30/72 (41%), Positives = 47/72 (64%), Gaps = 8/72 (11%)
Query: 60 NMTRNRYTNIKTYEKTRIKLKVVQGN---DYINASDIRLQIEGQSKAPSHFIACQGPLPN 116
N +NRY NI +Y+ +R++L V+ G+ DYINA+ I+G + P H+IA QGP+
Sbjct: 915 NRNKNRYGNIISYDHSRVRLLVLDGDPHSDYINAN----YIDGYHR-PRHYIATQGPMQE 969
Query: 117 TWPQFWQMVYQQ 128
T FW+M++Q+
Sbjct: 970 TVKDFWRMIWQE 981
>Hs19743927 [T] KOG4228 Protein tyrosine phosphatase
Length = 1463
Score = 58.9 bits (141), Expect = 2e-09
Identities = 30/72 (41%), Positives = 47/72 (64%), Gaps = 8/72 (11%)
Query: 60 NMTRNRYTNIKTYEKTRIKLKVVQGN---DYINASDIRLQIEGQSKAPSHFIACQGPLPN 116
N +NRY NI +Y+ +R++L V+ G+ DYINA+ I+G + P H+IA QGP+
Sbjct: 934 NRNKNRYGNIISYDHSRVRLLVLDGDPHSDYINAN----YIDGYHR-PRHYIATQGPMQE 988
Query: 117 TWPQFWQMVYQQ 128
T FW+M++Q+
Sbjct: 989 TVKDFWRMIWQE 1000
>Hs19743925 [T] KOG4228 Protein tyrosine phosphatase
Length = 1505
Score = 58.9 bits (141), Expect = 2e-09
Identities = 30/83 (36%), Positives = 54/83 (64%), Gaps = 8/83 (9%)
Query: 49 EWTFGVSDAKCNMTRNRYTNIKTYEKTRIKLKVVQG---NDYINASDIRLQIEGQSKAPS 105
++T+ S+ + N +NRY N+ Y+ +R+ L+ ++G +DYINA+ ++G + +
Sbjct: 962 QFTWEHSNLEVNKPKNRYANVIAYDHSRVILQPIEGIMGSDYINAN----YVDGYRRQNA 1017
Query: 106 HFIACQGPLPNTWPQFWQMVYQQ 128
+IA QGPLP T+ FW+MV++Q
Sbjct: 1018 -YIATQGPLPETFGDFWRMVWEQ 1039
Score = 54.3 bits (129), Expect = 5e-08
Identities = 33/74 (44%), Positives = 45/74 (60%), Gaps = 12/74 (16%)
Query: 59 CNMTRNRYTNIKTYEKTRI---KLKVVQGNDYINASDIRLQIEG--QSKAPSHFIACQGP 113
CN +NR NI YE TR+ ++ V+G+DYINAS I+G Q KA +IA QGP
Sbjct: 1261 CNKFKNRLVNIMPYESTRVCLQPIRGVEGSDYINAS----FIDGYRQQKA---YIATQGP 1313
Query: 114 LPNTWPQFWQMVYQ 127
L T FW+M+++
Sbjct: 1314 LAETTEDFWRMLWE 1327
>Hs19743923 [T] KOG4228 Protein tyrosine phosphatase
Length = 1910
Score = 58.9 bits (141), Expect = 2e-09
Identities = 30/83 (36%), Positives = 54/83 (64%), Gaps = 8/83 (9%)
Query: 49 EWTFGVSDAKCNMTRNRYTNIKTYEKTRIKLKVVQG---NDYINASDIRLQIEGQSKAPS 105
++T+ S+ + N +NRY N+ Y+ +R+ L+ ++G +DYINA+ ++G + +
Sbjct: 1367 QFTWEHSNLEVNKPKNRYANVIAYDHSRVILQPIEGIMGSDYINAN----YVDGYRRQNA 1422
Query: 106 HFIACQGPLPNTWPQFWQMVYQQ 128
+IA QGPLP T+ FW+MV++Q
Sbjct: 1423 -YIATQGPLPETFGDFWRMVWEQ 1444
Score = 54.3 bits (129), Expect = 5e-08
Identities = 33/74 (44%), Positives = 45/74 (60%), Gaps = 12/74 (16%)
Query: 59 CNMTRNRYTNIKTYEKTRI---KLKVVQGNDYINASDIRLQIEG--QSKAPSHFIACQGP 113
CN +NR NI YE TR+ ++ V+G+DYINAS I+G Q KA +IA QGP
Sbjct: 1666 CNKFKNRLVNIMPYESTRVCLQPIRGVEGSDYINAS----FIDGYRQQKA---YIATQGP 1718
Query: 114 LPNTWPQFWQMVYQ 127
L T FW+M+++
Sbjct: 1719 LAETTEDFWRMLWE 1732
>Hs19743921 [T] KOG4228 Protein tyrosine phosphatase
Length = 1501
Score = 58.9 bits (141), Expect = 2e-09
Identities = 30/83 (36%), Positives = 54/83 (64%), Gaps = 8/83 (9%)
Query: 49 EWTFGVSDAKCNMTRNRYTNIKTYEKTRIKLKVVQG---NDYINASDIRLQIEGQSKAPS 105
++T+ S+ + N +NRY N+ Y+ +R+ L+ ++G +DYINA+ ++G + +
Sbjct: 958 QFTWEHSNLEVNKPKNRYANVIAYDHSRVILQPIEGIMGSDYINAN----YVDGYRRQNA 1013
Query: 106 HFIACQGPLPNTWPQFWQMVYQQ 128
+IA QGPLP T+ FW+MV++Q
Sbjct: 1014 -YIATQGPLPETFGDFWRMVWEQ 1035
Score = 54.3 bits (129), Expect = 5e-08
Identities = 33/74 (44%), Positives = 45/74 (60%), Gaps = 12/74 (16%)
Query: 59 CNMTRNRYTNIKTYEKTRI---KLKVVQGNDYINASDIRLQIEG--QSKAPSHFIACQGP 113
CN +NR NI YE TR+ ++ V+G+DYINAS I+G Q KA +IA QGP
Sbjct: 1257 CNKFKNRLVNIMPYESTRVCLQPIRGVEGSDYINAS----FIDGYRQQKA---YIATQGP 1309
Query: 114 LPNTWPQFWQMVYQ 127
L T FW+M+++
Sbjct: 1310 LAETTEDFWRMLWE 1323
>Hs19743919 [T] KOG4228 Protein tyrosine phosphatase
Length = 1948
Score = 58.9 bits (141), Expect = 2e-09
Identities = 30/83 (36%), Positives = 54/83 (64%), Gaps = 8/83 (9%)
Query: 49 EWTFGVSDAKCNMTRNRYTNIKTYEKTRIKLKVVQG---NDYINASDIRLQIEGQSKAPS 105
++T+ S+ + N +NRY N+ Y+ +R+ L+ ++G +DYINA+ ++G + +
Sbjct: 1405 QFTWEHSNLEVNKPKNRYANVIAYDHSRVILQPIEGIMGSDYINAN----YVDGYRRQNA 1460
Query: 106 HFIACQGPLPNTWPQFWQMVYQQ 128
+IA QGPLP T+ FW+MV++Q
Sbjct: 1461 -YIATQGPLPETFGDFWRMVWEQ 1482
Score = 54.3 bits (129), Expect = 5e-08
Identities = 33/74 (44%), Positives = 45/74 (60%), Gaps = 12/74 (16%)
Query: 59 CNMTRNRYTNIKTYEKTRI---KLKVVQGNDYINASDIRLQIEG--QSKAPSHFIACQGP 113
CN +NR NI YE TR+ ++ V+G+DYINAS I+G Q KA +IA QGP
Sbjct: 1704 CNKFKNRLVNIMPYESTRVCLQPIRGVEGSDYINAS----FIDGYRQQKA---YIATQGP 1756
Query: 114 LPNTWPQFWQMVYQ 127
L T FW+M+++
Sbjct: 1757 LAETTEDFWRMLWE 1770
>At1g71860 [T] KOG0789 Protein tyrosine phosphatase
Length = 340
Score = 58.9 bits (141), Expect = 2e-09
Identities = 33/75 (44%), Positives = 47/75 (62%), Gaps = 7/75 (9%)
Query: 60 NMTRNRYTNIKTYEKTRIKL---KVVQGNDYINASDIRLQIEGQSKAPSHFIACQGPLPN 116
N+ +NRY+++ ++K RI L K Y+NAS I+ +S++ S FIA QGPLP+
Sbjct: 87 NVEKNRYSDVVPFDKNRIVLNPCKDSSAKGYVNASLIKTS---ESESISQFIATQGPLPH 143
Query: 117 TWPQFWQMVYQQ-CP 130
T FW+MV QQ CP
Sbjct: 144 TMEDFWEMVIQQHCP 158
>Hs4506311 [T] KOG4228 Protein tyrosine phosphatase
Length = 1897
Score = 58.2 bits (139), Expect = 3e-09
Identities = 32/83 (38%), Positives = 51/83 (60%), Gaps = 8/83 (9%)
Query: 49 EWTFGVSDAKCNMTRNRYTNIKTYEKTRIKLKVVQG---NDYINASDIRLQIEGQSKAPS 105
++T+ S+ + N +NRY N+ Y+ +R+ L + G +DYINA+ I+G K +
Sbjct: 1354 QFTWENSNLEVNKPKNRYANVIAYDHSRVILTSIDGVPGSDYINAN----YIDGYRKQNA 1409
Query: 106 HFIACQGPLPNTWPQFWQMVYQQ 128
+IA QGPLP T FW+MV++Q
Sbjct: 1410 -YIATQGPLPETMGDFWRMVWEQ 1431
Score = 51.6 bits (122), Expect = 3e-07
Identities = 31/72 (43%), Positives = 43/72 (59%), Gaps = 8/72 (11%)
Query: 59 CNMTRNRYTNIKTYEKTRI---KLKVVQGNDYINASDIRLQIEGQSKAPSHFIACQGPLP 115
CN +NR NI YE TR+ ++ V+G+DYINAS L Q KA +IA QGPL
Sbjct: 1653 CNKFKNRLVNIMPYELTRVCLQPIRGVEGSDYINAS--FLDGYRQQKA---YIATQGPLA 1707
Query: 116 NTWPQFWQMVYQ 127
+ FW+M+++
Sbjct: 1708 ESTEDFWRMLWE 1719
>Hs18860896 [T] KOG4228 Protein tyrosine phosphatase
Length = 1888
Score = 58.2 bits (139), Expect = 3e-09
Identities = 32/83 (38%), Positives = 51/83 (60%), Gaps = 8/83 (9%)
Query: 49 EWTFGVSDAKCNMTRNRYTNIKTYEKTRIKLKVVQG---NDYINASDIRLQIEGQSKAPS 105
++T+ S+ + N +NRY N+ Y+ +R+ L + G +DYINA+ I+G K +
Sbjct: 1345 QFTWENSNLEVNKPKNRYANVIAYDHSRVILTSIDGVPGSDYINAN----YIDGYRKQNA 1400
Query: 106 HFIACQGPLPNTWPQFWQMVYQQ 128
+IA QGPLP T FW+MV++Q
Sbjct: 1401 -YIATQGPLPETMGDFWRMVWEQ 1422
Score = 51.6 bits (122), Expect = 3e-07
Identities = 31/72 (43%), Positives = 43/72 (59%), Gaps = 8/72 (11%)
Query: 59 CNMTRNRYTNIKTYEKTRI---KLKVVQGNDYINASDIRLQIEGQSKAPSHFIACQGPLP 115
CN +NR NI YE TR+ ++ V+G+DYINAS L Q KA +IA QGPL
Sbjct: 1644 CNKFKNRLVNIMPYELTRVCLQPIRGVEGSDYINAS--FLDGYRQQKA---YIATQGPLA 1698
Query: 116 NTWPQFWQMVYQ 127
+ FW+M+++
Sbjct: 1699 ESTEDFWRMLWE 1710
>Hs18860898_2 [T] KOG0789 Protein tyrosine phosphatase
Length = 745
Score = 58.2 bits (139), Expect = 3e-09
Identities = 30/74 (40%), Positives = 49/74 (65%), Gaps = 10/74 (13%)
Query: 60 NMTRNRYTNIKTYEKTRIKLKVVQG-----NDYINASDIRLQIEGQSKAPSHFIACQGPL 114
N +NRY NI Y+ +R+KL+ + G +DYINA+ ++G +KA + +IA QGPL
Sbjct: 174 NKHKNRYINILAYDHSRVKLRPLPGKDSKHSDYINAN----YVDGYNKAKA-YIATQGPL 228
Query: 115 PNTWPQFWQMVYQQ 128
+T+ FW+M+++Q
Sbjct: 229 KSTFEDFWRMIWEQ 242
>SPAC11E3.09 [T] KOG0791 Protein tyrosine phosphatase contains fn3 domain
Length = 303
Score = 57.8 bits (138), Expect = 4e-09
Identities = 32/77 (41%), Positives = 46/77 (59%), Gaps = 8/77 (10%)
Query: 57 AKCNMTRNRYTNIKTYEKTRIKLKVV--QGNDYINASDIRLQIEGQSKAPSHFIACQGPL 114
+K + RNRY+NI YE TR++L + + DYINAS +++ + FIA QGP
Sbjct: 46 SKKALARNRYSNIVPYENTRVRLDPMWKEACDYINASIVKIP------SGKTFIATQGPT 99
Query: 115 PNTWPQFWQMVYQQCPK 131
N+ FW+MV+Q PK
Sbjct: 100 SNSIDVFWKMVWQSVPK 116
>Hs4885567 [T] KOG0792 Protein tyrosine phosphatase PTPMEG contains FERM domain
Length = 1187
Score = 57.8 bits (138), Expect = 4e-09
Identities = 31/71 (43%), Positives = 45/71 (62%), Gaps = 5/71 (7%)
Query: 60 NMTRNRYTNIKTYEKTRIKLKVVQGND--YINASDIRLQIEGQSKAPSHFIACQGPLPNT 117
N R+R + YE+ R++L + N+ YINAS I++ + G A H+IA QGPLP+T
Sbjct: 933 NAERSRIREVVPYEENRVELIPTKENNTGYINASHIKVVVGG---AEWHYIATQGPLPHT 989
Query: 118 WPQFWQMVYQQ 128
FWQMV++Q
Sbjct: 990 CHDFWQMVWEQ 1000
>Hs4506313 [T] KOG0791 Protein tyrosine phosphatase contains fn3 domain
Length = 1118
Score = 57.8 bits (138), Expect = 4e-09
Identities = 32/78 (41%), Positives = 46/78 (58%), Gaps = 8/78 (10%)
Query: 54 VSDAKCNMTRNRYTNIKTYEKTRIKLKVVQ---GNDYINASDIRLQIEGQSKAPSHFIAC 110
V+ A N +NRY N+ Y+ +R+ LK + G+DYINAS + +P FIA
Sbjct: 840 VASASENNAKNRYRNVLPYDWSRVPLKPIHEEPGSDYINASFMP-----GLWSPQEFIAT 894
Query: 111 QGPLPNTWPQFWQMVYQQ 128
QGPLP T FW++V++Q
Sbjct: 895 QGPLPQTVGDFWRLVWEQ 912
>Hs4506309 [T] KOG4228 Protein tyrosine phosphatase
Length = 1912
Score = 57.4 bits (137), Expect = 5e-09
Identities = 29/83 (34%), Positives = 52/83 (61%), Gaps = 8/83 (9%)
Query: 49 EWTFGVSDAKCNMTRNRYTNIKTYEKTRIKLKVVQG---NDYINASDIRLQIEGQSKAPS 105
++T+ S+ + N +NRY N+ Y+ +R+ L ++G +DY+NA+ I+G K +
Sbjct: 1369 QFTWEHSNLEVNKPKNRYANVIAYDHSRVLLSAIEGIPGSDYVNAN----YIDGYRKQNA 1424
Query: 106 HFIACQGPLPNTWPQFWQMVYQQ 128
+IA QG LP T+ FW+M+++Q
Sbjct: 1425 -YIATQGSLPETFGDFWRMIWEQ 1446
Score = 54.3 bits (129), Expect = 5e-08
Identities = 33/74 (44%), Positives = 45/74 (60%), Gaps = 12/74 (16%)
Query: 59 CNMTRNRYTNIKTYEKTRI---KLKVVQGNDYINASDIRLQIEG--QSKAPSHFIACQGP 113
CN +NR NI YE TR+ ++ V+G+DYINAS I+G Q KA +IA QGP
Sbjct: 1668 CNKFKNRLVNIMPYESTRVCLQPIRGVEGSDYINAS----FIDGYRQQKA---YIATQGP 1720
Query: 114 LPNTWPQFWQMVYQ 127
L T FW+M+++
Sbjct: 1721 LAETTEDFWRMLWE 1734
>Hs18860894 [T] KOG4228 Protein tyrosine phosphatase
Length = 1501
Score = 57.4 bits (137), Expect = 5e-09
Identities = 29/83 (34%), Positives = 52/83 (61%), Gaps = 8/83 (9%)
Query: 49 EWTFGVSDAKCNMTRNRYTNIKTYEKTRIKLKVVQG---NDYINASDIRLQIEGQSKAPS 105
++T+ S+ + N +NRY N+ Y+ +R+ L ++G +DY+NA+ I+G K +
Sbjct: 958 QFTWEHSNLEVNKPKNRYANVIAYDHSRVLLSAIEGIPGSDYVNAN----YIDGYRKQNA 1013
Query: 106 HFIACQGPLPNTWPQFWQMVYQQ 128
+IA QG LP T+ FW+M+++Q
Sbjct: 1014 -YIATQGSLPETFGDFWRMIWEQ 1035
Score = 54.3 bits (129), Expect = 5e-08
Identities = 33/74 (44%), Positives = 45/74 (60%), Gaps = 12/74 (16%)
Query: 59 CNMTRNRYTNIKTYEKTRI---KLKVVQGNDYINASDIRLQIEG--QSKAPSHFIACQGP 113
CN +NR NI YE TR+ ++ V+G+DYINAS I+G Q KA +IA QGP
Sbjct: 1257 CNKFKNRLVNIMPYESTRVCLQPIRGVEGSDYINAS----FIDGYRQQKA---YIATQGP 1309
Query: 114 LPNTWPQFWQMVYQ 127
L T FW+M+++
Sbjct: 1310 LAETTEDFWRMLWE 1323
>Hs18860892 [T] KOG4228 Protein tyrosine phosphatase
Length = 1903
Score = 57.4 bits (137), Expect = 5e-09
Identities = 29/83 (34%), Positives = 52/83 (61%), Gaps = 8/83 (9%)
Query: 49 EWTFGVSDAKCNMTRNRYTNIKTYEKTRIKLKVVQG---NDYINASDIRLQIEGQSKAPS 105
++T+ S+ + N +NRY N+ Y+ +R+ L ++G +DY+NA+ I+G K +
Sbjct: 1360 QFTWEHSNLEVNKPKNRYANVIAYDHSRVLLSAIEGIPGSDYVNAN----YIDGYRKQNA 1415
Query: 106 HFIACQGPLPNTWPQFWQMVYQQ 128
+IA QG LP T+ FW+M+++Q
Sbjct: 1416 -YIATQGSLPETFGDFWRMIWEQ 1437
Score = 54.3 bits (129), Expect = 5e-08
Identities = 33/74 (44%), Positives = 45/74 (60%), Gaps = 12/74 (16%)
Query: 59 CNMTRNRYTNIKTYEKTRI---KLKVVQGNDYINASDIRLQIEG--QSKAPSHFIACQGP 113
CN +NR NI YE TR+ ++ V+G+DYINAS I+G Q KA +IA QGP
Sbjct: 1659 CNKFKNRLVNIMPYESTRVCLQPIRGVEGSDYINAS----FIDGYRQQKA---YIATQGP 1711
Query: 114 LPNTWPQFWQMVYQ 127
L T FW+M+++
Sbjct: 1712 LAETTEDFWRMLWE 1725
>Hs18860890 [T] KOG4228 Protein tyrosine phosphatase
Length = 1899
Score = 57.4 bits (137), Expect = 5e-09
Identities = 29/83 (34%), Positives = 52/83 (61%), Gaps = 8/83 (9%)
Query: 49 EWTFGVSDAKCNMTRNRYTNIKTYEKTRIKLKVVQG---NDYINASDIRLQIEGQSKAPS 105
++T+ S+ + N +NRY N+ Y+ +R+ L ++G +DY+NA+ I+G K +
Sbjct: 1356 QFTWEHSNLEVNKPKNRYANVIAYDHSRVLLSAIEGIPGSDYVNAN----YIDGYRKQNA 1411
Query: 106 HFIACQGPLPNTWPQFWQMVYQQ 128
+IA QG LP T+ FW+M+++Q
Sbjct: 1412 -YIATQGSLPETFGDFWRMIWEQ 1433
Score = 54.3 bits (129), Expect = 5e-08
Identities = 33/74 (44%), Positives = 45/74 (60%), Gaps = 12/74 (16%)
Query: 59 CNMTRNRYTNIKTYEKTRI---KLKVVQGNDYINASDIRLQIEG--QSKAPSHFIACQGP 113
CN +NR NI YE TR+ ++ V+G+DYINAS I+G Q KA +IA QGP
Sbjct: 1655 CNKFKNRLVNIMPYESTRVCLQPIRGVEGSDYINAS----FIDGYRQQKA---YIATQGP 1707
Query: 114 LPNTWPQFWQMVYQ 127
L T FW+M+++
Sbjct: 1708 LAETTEDFWRMLWE 1721
>7290546 [T] KOG0791 Protein tyrosine phosphatase contains fn3 domain
Length = 1767
Score = 57.0 bits (136), Expect = 7e-09
Identities = 34/91 (37%), Positives = 53/91 (57%), Gaps = 10/91 (10%)
Query: 46 RDSEWTFGVSDAKCNMTRNRYTNIKTYEKTRIKLKVV---QGNDYINASDIRLQIEGQSK 102
RD +F ++ CN +NR+TNI Y+ +R KL+ V G+DYINA+ + G +
Sbjct: 1341 RDQACSF--ANLPCNRPKNRFTNILPYDHSRFKLQPVDDDDGSDYINAN----YMPGHN- 1393
Query: 103 APSHFIACQGPLPNTWPQFWQMVYQQCPKKI 133
+P FI QGPL +T +FW+M ++ + I
Sbjct: 1394 SPREFIVTQGPLHSTREEFWRMCWESNSRAI 1424
>7291964 [T] KOG0792 Protein tyrosine phosphatase PTPMEG contains FERM
domain
Length = 916
Score = 56.6 bits (135), Expect = 9e-09
Identities = 29/69 (42%), Positives = 42/69 (60%), Gaps = 2/69 (2%)
Query: 60 NMTRNRYTNIKTYEKTRIKLKVVQGNDYINASDIRLQIEGQSKAPSHFIACQGPLPNTWP 119
N +NRY +I Y+ TR+ L DYINA+ + ++I G A + +IA QGPL +T
Sbjct: 608 NAPKNRYRDISPYDCTRVSLVNSLTGDYINANYVNMEIPG--GAVNRYIATQGPLASTTT 665
Query: 120 QFWQMVYQQ 128
FW+MV Q+
Sbjct: 666 DFWRMVQQE 674
>Hs18860904 [T] KOG4228 Protein tyrosine phosphatase
Length = 1452
Score = 56.2 bits (134), Expect = 1e-08
Identities = 28/72 (38%), Positives = 46/72 (63%), Gaps = 8/72 (11%)
Query: 60 NMTRNRYTNIKTYEKTRIKLKVVQGN---DYINASDIRLQIEGQSKAPSHFIACQGPLPN 116
N +NRY NI Y+ +R++L+ ++G+ DYIN + I+G + P+H+IA QGP+
Sbjct: 923 NRMKNRYGNIIAYDHSRVRLQTIEGDTNSDYINGN----YIDGYHR-PNHYIATQGPMQE 977
Query: 117 TWPQFWQMVYQQ 128
T FW+MV+ +
Sbjct: 978 TIYDFWRMVWHE 989
>Hs18860902 [T] KOG4228 Protein tyrosine phosphatase
Length = 1440
Score = 56.2 bits (134), Expect = 1e-08
Identities = 32/86 (37%), Positives = 50/86 (57%), Gaps = 10/86 (11%)
Query: 46 RDSEWTFGVSDAKCNMTRNRYTNIKTYEKTRIKLKVVQ---GNDYINASDIRLQIEGQSK 102
+ + W D N +NRY NI Y+ +R+ L+ V+ +DYINA+ I+G +
Sbjct: 899 QSASWDVAKKDQ--NRAKNRYGNIIAYDHSRVILQPVEDDPSSDYINAN----YIDGYQR 952
Query: 103 APSHFIACQGPLPNTWPQFWQMVYQQ 128
PSH+IA QGP+ T FW+M++Q+
Sbjct: 953 -PSHYIATQGPVHETVYDFWRMIWQE 977
>CE29409 [T] KOG4228 Protein tyrosine phosphatase
Length = 940
Score = 55.8 bits (133), Expect = 2e-08
Identities = 31/77 (40%), Positives = 46/77 (59%), Gaps = 8/77 (10%)
Query: 55 SDAKCNMTRNRYTNIKTYEKTRIKLKVVQG---NDYINASDIRLQIEGQSKAPSHFIACQ 111
S+ K N +NRY +I+ ++ TR+KLK + G +DYINA+ I+ K FIA Q
Sbjct: 808 SNRKENAIKNRYNDIRAFDDTRVKLKKINGDDYSDYINANFIK-----SWKEKKLFIAAQ 862
Query: 112 GPLPNTWPQFWQMVYQQ 128
P+ T FW+MV++Q
Sbjct: 863 APVDATIGDFWRMVWEQ 879
>CE29408 [T] KOG4228 Protein tyrosine phosphatase
Length = 1442
Score = 55.8 bits (133), Expect = 2e-08
Identities = 31/77 (40%), Positives = 46/77 (59%), Gaps = 8/77 (10%)
Query: 55 SDAKCNMTRNRYTNIKTYEKTRIKLKVVQG---NDYINASDIRLQIEGQSKAPSHFIACQ 111
S+ K N +NRY +I+ ++ TR+KLK + G +DYINA+ I+ K FIA Q
Sbjct: 843 SNRKENAIKNRYNDIRAFDDTRVKLKKINGDDYSDYINANFIK-----SWKEKKLFIAAQ 897
Query: 112 GPLPNTWPQFWQMVYQQ 128
P+ T FW+MV++Q
Sbjct: 898 APVDATIGDFWRMVWEQ 914
>CE26369 [T] KOG4228 Protein tyrosine phosphatase
Length = 1407
Score = 55.8 bits (133), Expect = 2e-08
Identities = 31/77 (40%), Positives = 46/77 (59%), Gaps = 8/77 (10%)
Query: 55 SDAKCNMTRNRYTNIKTYEKTRIKLKVVQG---NDYINASDIRLQIEGQSKAPSHFIACQ 111
S+ K N +NRY +I+ ++ TR+KLK + G +DYINA+ I+ K FIA Q
Sbjct: 808 SNRKENAIKNRYNDIRAFDDTRVKLKKINGDDYSDYINANFIK-----SWKEKKLFIAAQ 862
Query: 112 GPLPNTWPQFWQMVYQQ 128
P+ T FW+MV++Q
Sbjct: 863 APVDATIGDFWRMVWEQ 879
>Hs5902032 [T] KOG0792 Protein tyrosine phosphatase PTPMEG contains FERM
domain
Length = 1174
Score = 55.5 bits (132), Expect = 2e-08
Identities = 29/71 (40%), Positives = 43/71 (59%), Gaps = 5/71 (7%)
Query: 60 NMTRNRYTNIKTYEKTRIKLKVVQGND--YINASDIRLQIEGQSKAPSHFIACQGPLPNT 117
N RNR+ ++ Y+ R++L + N+ YINAS I++ + G +IA QGPL NT
Sbjct: 921 NAERNRFQDVLPYDDARVELVPTKENNTGYINASHIKVSVSG---IEWDYIATQGPLQNT 977
Query: 118 WPQFWQMVYQQ 128
FWQMV++Q
Sbjct: 978 CQDFWQMVWEQ 988
>SPAC26F1.10c [T] KOG0789 Protein tyrosine phosphatase
Length = 550
Score = 55.1 bits (131), Expect = 3e-08
Identities = 37/114 (32%), Positives = 59/114 (51%), Gaps = 11/114 (9%)
Query: 15 YLDQDDRDLLLKFRYIRQQEDARIRDGALHPRDSEWTFGVSDAKCNMTRNRYTNIKTYEK 74
+ + D L KF ++ E R+ + R+S+W+ S + + +NRYT+I Y
Sbjct: 252 FTNPDVATLYQKFLRLQSLEHQRLV--SCSDRNSQWSTVDSLSNTSYKKNRYTDIVPYNC 309
Query: 75 TRIKLKVVQGN--DYINASDIRLQIEGQSKAPSHFIACQGPLPNTWPQFWQMVY 126
TR+ LK + DYINAS I+ + S++IACQG + + FW MV+
Sbjct: 310 TRVHLKRTSPSELDYINASFIKTE-------TSNYIACQGSISRSISDFWHMVW 356
>Hs4506321 [T] KOG0793 Protein tyrosine phosphatase
Length = 979
Score = 55.1 bits (131), Expect = 3e-08
Identities = 33/80 (41%), Positives = 47/80 (58%), Gaps = 7/80 (8%)
Query: 51 TFGVSDAKCNMTRNRYTNIKTYEKTRIKLKVVQG---NDYINASDIRLQIEGQSKAPSHF 107
T + + N+ +NR+ + Y+ RIKLKV +DYINAS I IE + P+ +
Sbjct: 725 TCATAQGEGNIKKNRHPDFLPYDHARIKLKVESSPSRSDYINASPI---IEHDPRMPA-Y 780
Query: 108 IACQGPLPNTWPQFWQMVYQ 127
IA QGPL +T FWQMV++
Sbjct: 781 IATQGPLSHTIADFWQMVWE 800
>Hs22053842 [T] KOG0789 Protein tyrosine phosphatase
Length = 281
Score = 53.9 bits (128), Expect = 6e-08
Identities = 29/74 (39%), Positives = 43/74 (57%), Gaps = 6/74 (8%)
Query: 60 NMTRNRYTNIKTYEKTRIKLKVVQGNDYINASDIRLQIEGQSKAPSHFIACQGPLPNTWP 119
N RNRY ++ Y+ +R+KL+ + NDYINAS + ++ +A +I GPLPN
Sbjct: 42 NRNRNRYRDVSPYDHSRVKLQNTE-NDYINASLVDIE-----EARRSYILTPGPLPNMCC 95
Query: 120 QFWQMVYQQCPKKI 133
FW V+QQ K +
Sbjct: 96 HFWLTVWQQKTKAV 109
>CE15903 [T] KOG0789 Protein tyrosine phosphatase
Length = 490
Score = 53.9 bits (128), Expect = 6e-08
Identities = 32/78 (41%), Positives = 45/78 (57%), Gaps = 7/78 (8%)
Query: 51 TFGVSDAKCNMTRNRYTNIKTYEKTRIKLKVVQGNDYINASDIRLQIEGQSKAPSHFIAC 110
T+ DA N NRY +++ E+TR+ LK DYI+AS +R+ + QS +I
Sbjct: 196 TYTAYDA--NPDLNRYADVRCIEETRVVLKN-HDRDYIHASWMRMPGKDQST----YITT 248
Query: 111 QGPLPNTWPQFWQMVYQQ 128
QGPLP T FW M+YQ+
Sbjct: 249 QGPLPETLSDFWHMIYQE 266
>CE11200 [T] KOG0789 Protein tyrosine phosphatase
Length = 518
Score = 53.9 bits (128), Expect = 6e-08
Identities = 29/71 (40%), Positives = 42/71 (58%), Gaps = 5/71 (7%)
Query: 58 KCNMTRNRYTNIKTYEKTRIKLKVVQGNDYINASDIRLQIEGQSKAPSHFIACQGPLPNT 117
+ N NRY +++ E+TR+ LK DYI+AS +R+ + QS +I QGPLP T
Sbjct: 202 EANPDLNRYADVRCIEETRVVLKN-HDRDYIHASWMRMPGKDQST----YITTQGPLPET 256
Query: 118 WPQFWQMVYQQ 128
FW M+YQ+
Sbjct: 257 LSDFWHMIYQE 267
>7301780 [T] KOG0789 Protein tyrosine phosphatase
Length = 1285
Score = 53.9 bits (128), Expect = 6e-08
Identities = 30/73 (41%), Positives = 43/73 (58%), Gaps = 9/73 (12%)
Query: 60 NMTRNRYTNIKTYEKTRIKLKVVQGN----DYINASDIRLQIEGQSKAPSHFIACQGPLP 115
N +NRY NI Y+ +R+ L G DYINA+ I +G K + FI QGPLP
Sbjct: 490 NKRKNRYLNITAYDHSRVHLHPTPGQKKNLDYINANFI----DGYQKGHA-FIGTQGPLP 544
Query: 116 NTWPQFWQMVYQQ 128
+T+ FW+M+++Q
Sbjct: 545 DTFDCFWRMIWEQ 557
>Hs18491010 [T] KOG0791 Protein tyrosine phosphatase contains fn3 domain
Length = 1997
Score = 53.5 bits (127), Expect = 8e-08
Identities = 31/72 (43%), Positives = 40/72 (55%), Gaps = 8/72 (11%)
Query: 60 NMTRNRYTNIKTYEKTRIKLKVVQGN---DYINASDIRLQIEGQSKAPSHFIACQGPLPN 116
N +NRY NI Y+ TR+KL V + DYINAS I + +I QGPLP
Sbjct: 1727 NRGKNRYNNILPYDATRVKLSNVDDDPCSDYINASYIP-----GNNFRREYIVTQGPLPG 1781
Query: 117 TWPQFWQMVYQQ 128
T FW+MV++Q
Sbjct: 1782 TKDDFWKMVWEQ 1793
>Hs18860900 [T] KOG0791 Protein tyrosine phosphatase contains fn3 domain
Length = 1337
Score = 53.1 bits (126), Expect = 1e-07
Identities = 30/71 (42%), Positives = 43/71 (60%), Gaps = 7/71 (9%)
Query: 60 NMTRNRYTNIKTYEKTRIKLKVV--QGNDYINASDIRLQIEGQSKAPSHFIACQGPLPNT 117
N +NRY N+ Y+ +R+KL V +DYINA+ + G + FIA QGPLPNT
Sbjct: 1065 NRGKNRYNNVLPYDISRVKLSVQTHSTDDYINAN----YMPGYH-SKKDFIATQGPLPNT 1119
Query: 118 WPQFWQMVYQQ 128
FW+MV+++
Sbjct: 1120 LKDFWRMVWEK 1130
>Hs22052020_2 [T] KOG0789 Protein tyrosine phosphatase
Length = 307
Score = 52.4 bits (124), Expect = 2e-07
Identities = 33/86 (38%), Positives = 46/86 (53%), Gaps = 5/86 (5%)
Query: 42 ALHPRDSEWTFGVSDAKCNMTRNRYTNIKTYEKTRIKLKVVQGNDYINASDIRLQIEGQS 101
AL ++ F + N +NRY +I Y+ TR+ L + DYINAS IR+ G+
Sbjct: 52 ALELKNLPGEFNSGNQPSNREKNRYRDILPYDSTRVPLG--KSKDYINASYIRIVNCGEE 109
Query: 102 KAPSHFIACQGPLPNTWPQFWQMVYQ 127
+IA QGPL +T FWQMV +
Sbjct: 110 Y---FYIATQGPLLSTIDDFWQMVLE 132
>Hs4506303 [T] KOG4228 Protein tyrosine phosphatase
Length = 802
Score = 52.0 bits (123), Expect = 2e-07
Identities = 30/72 (41%), Positives = 41/72 (56%), Gaps = 8/72 (11%)
Query: 60 NMTRNRYTNIKTYEKTRIKLKVVQG---NDYINASDIRLQIEGQSKAPSHFIACQGPLPN 116
N +NRY NI Y+ +R+ L V+G +DYINAS I E + FIA QGP
Sbjct: 265 NKEKNRYVNILPYDHSRVHLTPVEGVPDSDYINASFINGYQE-----KNKFIAAQGPKEE 319
Query: 117 TWPQFWQMVYQQ 128
T FW+M+++Q
Sbjct: 320 TVNDFWRMIWEQ 331
>Hs18450369 [T] KOG4228 Protein tyrosine phosphatase
Length = 793
Score = 52.0 bits (123), Expect = 2e-07
Identities = 30/72 (41%), Positives = 41/72 (56%), Gaps = 8/72 (11%)
Query: 60 NMTRNRYTNIKTYEKTRIKLKVVQG---NDYINASDIRLQIEGQSKAPSHFIACQGPLPN 116
N +NRY NI Y+ +R+ L V+G +DYINAS I E + FIA QGP
Sbjct: 256 NKEKNRYVNILPYDHSRVHLTPVEGVPDSDYINASFINGYQE-----KNKFIAAQGPKEE 310
Query: 117 TWPQFWQMVYQQ 128
T FW+M+++Q
Sbjct: 311 TVNDFWRMIWEQ 322
>Hs18104993 [T] KOG0790 Protein tyrosine phosphatase Corkscrew and related SH2
domain enzymes
Length = 624
Score = 52.0 bits (123), Expect = 2e-07
Identities = 28/73 (38%), Positives = 43/73 (58%), Gaps = 4/73 (5%)
Query: 60 NMTRNRYTNIKTYEKTRIKLKV----VQGNDYINASDIRLQIEGQSKAPSHFIACQGPLP 115
N +NRY NI ++ +R+ L+ + G+DYINA+ I+ Q+ G + +IA QG L
Sbjct: 270 NKGKNRYKNILPFDHSRVILQGRDSNIPGSDYINANYIKNQLLGPDENAKTYIASQGCLE 329
Query: 116 NTWPQFWQMVYQQ 128
T FWQM +Q+
Sbjct: 330 ATVNDFWQMAWQE 342
>Hs18104991 [T] KOG0790 Protein tyrosine phosphatase Corkscrew and related SH2
domain enzymes
Length = 597
Score = 52.0 bits (123), Expect = 2e-07
Identities = 28/73 (38%), Positives = 43/73 (58%), Gaps = 4/73 (5%)
Query: 60 NMTRNRYTNIKTYEKTRIKLKV----VQGNDYINASDIRLQIEGQSKAPSHFIACQGPLP 115
N +NRY NI ++ +R+ L+ + G+DYINA+ I+ Q+ G + +IA QG L
Sbjct: 272 NKGKNRYKNILPFDHSRVILQGRDSNIPGSDYINANYIKNQLLGPDENAKTYIASQGCLE 331
Query: 116 NTWPQFWQMVYQQ 128
T FWQM +Q+
Sbjct: 332 ATVNDFWQMAWQE 344
>Hs18104989 [T] KOG0790 Protein tyrosine phosphatase Corkscrew and related SH2
domain enzymes
Length = 595
Score = 52.0 bits (123), Expect = 2e-07
Identities = 28/73 (38%), Positives = 43/73 (58%), Gaps = 4/73 (5%)
Query: 60 NMTRNRYTNIKTYEKTRIKLKV----VQGNDYINASDIRLQIEGQSKAPSHFIACQGPLP 115
N +NRY NI ++ +R+ L+ + G+DYINA+ I+ Q+ G + +IA QG L
Sbjct: 270 NKGKNRYKNILPFDHSRVILQGRDSNIPGSDYINANYIKNQLLGPDENAKTYIASQGCLE 329
Query: 116 NTWPQFWQMVYQQ 128
T FWQM +Q+
Sbjct: 330 ATVNDFWQMAWQE 342
>Hs5729993 [T] KOG4228 Protein tyrosine phosphatase
Length = 700
Score = 51.2 bits (121), Expect = 4e-07
Identities = 32/81 (39%), Positives = 47/81 (57%), Gaps = 8/81 (9%)
Query: 51 TFGVSDAKCNMTRNRYTNIKTYEKTRIKLKVVQG---NDYINASDIRLQIEGQSKAPSHF 107
TF +++ + N +NRY NI + +R+ L + G +DYINAS I+G K + F
Sbjct: 150 TFELANKEENREKNRYPNILPNDHSRVILSQLDGIPCSDYINAS----YIDGY-KEKNKF 204
Query: 108 IACQGPLPNTWPQFWQMVYQQ 128
IA QGP T FW+MV++Q
Sbjct: 205 IAAQGPKQETVNDFWRMVWEQ 225
>Hs18860859 [T] KOG4228 Protein tyrosine phosphatase
Length = 642
Score = 51.2 bits (121), Expect = 4e-07
Identities = 32/81 (39%), Positives = 47/81 (57%), Gaps = 8/81 (9%)
Query: 51 TFGVSDAKCNMTRNRYTNIKTYEKTRIKLKVVQG---NDYINASDIRLQIEGQSKAPSHF 107
TF +++ + N +NRY NI + +R+ L + G +DYINAS I+G K + F
Sbjct: 92 TFELANKEENREKNRYPNILPNDHSRVILSQLDGIPCSDYINAS----YIDGY-KEKNKF 146
Query: 108 IACQGPLPNTWPQFWQMVYQQ 128
IA QGP T FW+MV++Q
Sbjct: 147 IAAQGPKQETVNDFWRMVWEQ 167
>Hs18641364 [T] KOG4228 Protein tyrosine phosphatase
Length = 1256
Score = 51.2 bits (121), Expect = 4e-07
Identities = 28/72 (38%), Positives = 42/72 (57%), Gaps = 8/72 (11%)
Query: 60 NMTRNRYTNIKTYEKTRIKLKVVQGN---DYINASDIRLQIEGQSKAPSHFIACQGPLPN 116
N +NRY +I Y+ R++L + G+ +YINAS I+G K P +IA QGP
Sbjct: 627 NQNKNRYVDILPYDYNRVELSEINGDAGSNYINAS----YIDG-FKEPRKYIAAQGPRDE 681
Query: 117 TWPQFWQMVYQQ 128
T FW+M+++Q
Sbjct: 682 TVDDFWRMIWEQ 693
>Hs18641362 [T] KOG4228 Protein tyrosine phosphatase
Length = 1143
Score = 51.2 bits (121), Expect = 4e-07
Identities = 28/72 (38%), Positives = 42/72 (57%), Gaps = 8/72 (11%)
Query: 60 NMTRNRYTNIKTYEKTRIKLKVVQGN---DYINASDIRLQIEGQSKAPSHFIACQGPLPN 116
N +NRY +I Y+ R++L + G+ +YINAS I+G K P +IA QGP
Sbjct: 514 NQNKNRYVDILPYDYNRVELSEINGDAGSNYINAS----YIDG-FKEPRKYIAAQGPRDE 568
Query: 117 TWPQFWQMVYQQ 128
T FW+M+++Q
Sbjct: 569 TVDDFWRMIWEQ 580
>Hs18641347 [T] KOG4228 Protein tyrosine phosphatase
Length = 1304
Score = 51.2 bits (121), Expect = 4e-07
Identities = 28/72 (38%), Positives = 42/72 (57%), Gaps = 8/72 (11%)
Query: 60 NMTRNRYTNIKTYEKTRIKLKVVQGN---DYINASDIRLQIEGQSKAPSHFIACQGPLPN 116
N +NRY +I Y+ R++L + G+ +YINAS I+G K P +IA QGP
Sbjct: 675 NQNKNRYVDILPYDYNRVELSEINGDAGSNYINAS----YIDG-FKEPRKYIAAQGPRDE 729
Query: 117 TWPQFWQMVYQQ 128
T FW+M+++Q
Sbjct: 730 TVDDFWRMIWEQ 741
>Hs7706280 [T] KOG0789 Protein tyrosine phosphatase
Length = 807
Score = 50.8 bits (120), Expect = 5e-07
Identities = 35/123 (28%), Positives = 62/123 (49%), Gaps = 19/123 (15%)
Query: 19 DDRDLLLKF------RYIRQQEDARI-----RDGALHPRDSEWTFGVSDAKCNMTRNRYT 67
D R++L KF + I ++E A R + D + V++ N+ +NRY
Sbjct: 2 DQREILQKFLDEAQSKKITKEEFANEFLKLKRQSTKYKADKTYPTTVAEKPKNIKKNRYK 61
Query: 68 NIKTYEKTRIKLKVVQGND---YINASDIRLQIEGQSKAPSHFIACQGPLPNTWPQFWQM 124
+I Y+ +R++L ++ ++ YINA+ I+ P +IA QGPL T FW+M
Sbjct: 62 DILPYDYSRVELSLITSDEDSSYINANFIK-----GVYGPKAYIATQGPLSTTLLDFWRM 116
Query: 125 VYQ 127
+++
Sbjct: 117 IWE 119
>Hs19743931 [T] KOG4228 Protein tyrosine phosphatase
Length = 1440
Score = 50.8 bits (120), Expect = 5e-07
Identities = 29/70 (41%), Positives = 44/70 (62%), Gaps = 6/70 (8%)
Query: 64 NRYTNIKTYEKTRIKLKVVQGN---DYINAS--DIRLQIEGQSKAPSHFIACQGPLPNTW 118
+R + Y++ R+KL + G+ DYINA+ DIR+ EG ++ +HFIA QGP P
Sbjct: 907 SRQEPMPAYDRHRVKLHPMLGDPNADYINANYIDIRINREGYHRS-NHFIATQGPKPEMV 965
Query: 119 PQFWQMVYQQ 128
FW+MV+Q+
Sbjct: 966 YDFWRMVWQE 975
>Hs18375644 [T] KOG0790 Protein tyrosine phosphatase Corkscrew and related SH2
domain enzymes
Length = 460
Score = 50.8 bits (120), Expect = 5e-07
Identities = 31/76 (40%), Positives = 41/76 (53%), Gaps = 7/76 (9%)
Query: 60 NMTRNRYTNIKTYEKTRIKLKVVQGN----DYINASDIRLQIE---GQSKAPSHFIACQG 112
N +NRY NI ++ TR+ L N DYINA+ I + E SK +IA QG
Sbjct: 273 NKNKNRYKNILPFDHTRVVLHDGDPNEPVSDYINANIIMPEFETKCNNSKPKKSYIATQG 332
Query: 113 PLPNTWPQFWQMVYQQ 128
L NT FW+MV+Q+
Sbjct: 333 CLQNTVNDFWRMVFQE 348
>Hs18375642 [T] KOG0790 Protein tyrosine phosphatase Corkscrew and related SH2
domain enzymes
Length = 593
Score = 50.8 bits (120), Expect = 5e-07
Identities = 31/76 (40%), Positives = 41/76 (53%), Gaps = 7/76 (9%)
Query: 60 NMTRNRYTNIKTYEKTRIKLKVVQGN----DYINASDIRLQIE---GQSKAPSHFIACQG 112
N +NRY NI ++ TR+ L N DYINA+ I + E SK +IA QG
Sbjct: 273 NKNKNRYKNILPFDHTRVVLHDGDPNEPVSDYINANIIMPEFETKCNNSKPKKSYIATQG 332
Query: 113 PLPNTWPQFWQMVYQQ 128
L NT FW+MV+Q+
Sbjct: 333 CLQNTVNDFWRMVFQE 348
>CE10628 [T] KOG0789 Protein tyrosine phosphatase
Length = 374
Score = 50.8 bits (120), Expect = 5e-07
Identities = 33/93 (35%), Positives = 47/93 (50%), Gaps = 6/93 (6%)
Query: 36 ARIRDGALHPRDSEWTFGVSDAKCNMTRNRYTNIKTYEKTRIKLKVV-QGNDYINASDIR 94
+++RD + V K N +NRYT+IK EKTR+ L +DYI+A+ +
Sbjct: 66 SKLRDEFSEVANKNPNVPVDAFKSNPEKNRYTDIKCIEKTRVILTTDGASSDYIHANYVG 125
Query: 95 LQIEGQSKAPSHFIACQGPLPNTWPQFWQMVYQ 127
+ I+ P FI QGP +T FW MV Q
Sbjct: 126 ISIK-----PKKFICTQGPKDSTIYDFWAMVIQ 153
>Hs19743914 [T] KOG0793 Protein tyrosine phosphatase
Length = 986
Score = 50.4 bits (119), Expect = 7e-07
Identities = 30/77 (38%), Positives = 46/77 (58%), Gaps = 7/77 (9%)
Query: 54 VSDAKCNMTRNRYTNIKTYEKTRIKLKVVQGN---DYINASDIRLQIEGQSKAPSHFIAC 110
V+ + N+ +NR + TY+ +R+ LK + DYINAS I ++ + P+ +IA
Sbjct: 735 VAQREENVPKNRSLAVLTYDHSRVLLKAENSHSHSDYINASPI---MDHDPRNPA-YIAT 790
Query: 111 QGPLPNTWPQFWQMVYQ 127
QGPLP T FWQMV++
Sbjct: 791 QGPLPATVADFWQMVWE 807
>Hs19743912 [T] KOG0793 Protein tyrosine phosphatase
Length = 998
Score = 50.4 bits (119), Expect = 7e-07
Identities = 30/77 (38%), Positives = 46/77 (58%), Gaps = 7/77 (9%)
Query: 54 VSDAKCNMTRNRYTNIKTYEKTRIKLKVVQGN---DYINASDIRLQIEGQSKAPSHFIAC 110
V+ + N+ +NR + TY+ +R+ LK + DYINAS I ++ + P+ +IA
Sbjct: 747 VAQREENVPKNRSLAVLTYDHSRVLLKAENSHSHSDYINASPI---MDHDPRNPA-YIAT 802
Query: 111 QGPLPNTWPQFWQMVYQ 127
QGPLP T FWQMV++
Sbjct: 803 QGPLPATVADFWQMVWE 819
>Hs18375655 [T] KOG0789 Protein tyrosine phosphatase
Length = 460
Score = 50.4 bits (119), Expect = 7e-07
Identities = 27/71 (38%), Positives = 46/71 (64%), Gaps = 8/71 (11%)
Query: 60 NMTRNRYTNIKTYEKTRIKLKVVQG---NDYINASDIRLQIEGQSKAPSHFIACQGPLPN 116
N+ +NRY ++ Y++TR+ L ++Q +DYIN + IR ++G +IA QGPLP+
Sbjct: 56 NVRKNRYKDVLPYDQTRVILSLLQEEGHSDYINGNFIR-GVDGSLA----YIATQGPLPH 110
Query: 117 TWPQFWQMVYQ 127
T FW++V++
Sbjct: 111 TLLDFWRLVWE 121
>Hs15619018 [T] KOG0789 Protein tyrosine phosphatase
Length = 691
Score = 50.4 bits (119), Expect = 7e-07
Identities = 35/123 (28%), Positives = 62/123 (49%), Gaps = 19/123 (15%)
Query: 19 DDRDLLLKF------RYIRQQEDARI-----RDGALHPRDSEWTFGVSDAKCNMTRNRYT 67
D R++L KF + I ++E A R + D + V++ N+ +NRY
Sbjct: 2 DQREILQKFLDEAQSKKITKEEFANEFLKLKRQSTKYKADKTYPTTVAENAKNIKKNRYK 61
Query: 68 NIKTYEKTRIKLKVVQGND---YINASDIRLQIEGQSKAPSHFIACQGPLPNTWPQFWQM 124
+I Y+ +R++L ++ ++ YINA+ I+ P +IA QGPL T FW+M
Sbjct: 62 DILPYDYSRVELSLITSDEDSSYINANFIK-----GVYGPKAYIATQGPLSTTLLDFWRM 116
Query: 125 VYQ 127
+++
Sbjct: 117 IWE 119
>Hs11386149 [T] KOG0793 Protein tyrosine phosphatase
Length = 1015
Score = 50.4 bits (119), Expect = 7e-07
Identities = 30/77 (38%), Positives = 46/77 (58%), Gaps = 7/77 (9%)
Query: 54 VSDAKCNMTRNRYTNIKTYEKTRIKLKVVQGN---DYINASDIRLQIEGQSKAPSHFIAC 110
V+ + N+ +NR + TY+ +R+ LK + DYINAS I ++ + P+ +IA
Sbjct: 764 VAQREENVPKNRSLAVLTYDHSRVLLKAENSHSHSDYINASPI---MDHDPRNPA-YIAT 819
Query: 111 QGPLPNTWPQFWQMVYQ 127
QGPLP T FWQMV++
Sbjct: 820 QGPLPATVADFWQMVWE 836
>Hs4506329 [T] KOG0789 Protein tyrosine phosphatase
Length = 2314
Score = 50.1 bits (118), Expect = 9e-07
Identities = 28/73 (38%), Positives = 44/73 (59%), Gaps = 10/73 (13%)
Query: 60 NMTRNRYTNIKTYEKTRIKL-----KVVQGNDYINASDIRLQIEGQSKAPSHFIACQGPL 114
N +NRY NI Y+ +R+KL K + DYINA+ ++G ++ P +IA QGPL
Sbjct: 1749 NKHKNRYINIVAYDHSRVKLAQLAEKDGKLTDYINAN----YVDGYNR-PKAYIAAQGPL 1803
Query: 115 PNTWPQFWQMVYQ 127
+T FW+M+++
Sbjct: 1804 KSTAEDFWRMIWE 1816
>CE02705 [T] KOG0790 Protein tyrosine phosphatase Corkscrew and related SH2
domain enzymes
Length = 668
Score = 50.1 bits (118), Expect = 9e-07
Identities = 30/77 (38%), Positives = 41/77 (52%), Gaps = 8/77 (10%)
Query: 60 NMTRNRYTNIKTYEKTRIKLKV---VQGNDYINASDIRLQIEGQSK-----APSHFIACQ 111
N +NRY NI ++ TR+ L G+DYINAS +R + ++K FIA Q
Sbjct: 292 NAEKNRYKNIVPFDHTRVILTDRPNTPGSDYINASYVRFENSQRTKNVTFACEKSFIATQ 351
Query: 112 GPLPNTWPQFWQMVYQQ 128
G L T FW MV+Q+
Sbjct: 352 GCLETTISDFWSMVWQE 368
>Hs18375652 [T] KOG0789 Protein tyrosine phosphatase
Length = 780
Score = 49.7 bits (117), Expect = 1e-06
Identities = 26/71 (36%), Positives = 43/71 (59%), Gaps = 8/71 (11%)
Query: 60 NMTRNRYTNIKTYEKTRIKLKVV---QGNDYINASDIRLQIEGQSKAPSHFIACQGPLPN 116
N+ +NRY +I ++ +R+KL + Q +DYINA+ I+ P ++A QGPL N
Sbjct: 58 NVKKNRYKDILPFDHSRVKLTLKTPSQDSDYINANFIK-----GVYGPKAYVATQGPLAN 112
Query: 117 TWPQFWQMVYQ 127
T FW+M+++
Sbjct: 113 TVIDFWRMIWE 123
>7292074 [T] KOG0789 Protein tyrosine phosphatase
Length = 548
Score = 49.7 bits (117), Expect = 1e-06
Identities = 29/84 (34%), Positives = 50/84 (59%), Gaps = 8/84 (9%)
Query: 46 RDSEWTFGVSDAKCNMTRNRYTNIKTYEKTRIKLKVVQGN-DYINASDIRLQIEGQSKAP 104
++ +++ S+ N NRY ++ Y+ +RI LK +G+ DYINA+ ++L+ +A
Sbjct: 46 KEKQFSTSESERHTNRGLNRYRDVNPYDHSRIVLK--RGSVDYINANLVQLE-----RAE 98
Query: 105 SHFIACQGPLPNTWPQFWQMVYQQ 128
+I QGPL +T FW MV++Q
Sbjct: 99 RQYILTQGPLVDTVGHFWLMVWEQ 122
>Hs14736297_2 [T] KOG0789 Protein tyrosine phosphatase
Length = 447
Score = 49.7 bits (117), Expect = 1e-06
Identities = 27/75 (36%), Positives = 43/75 (57%), Gaps = 5/75 (6%)
Query: 54 VSDAKCNMTRNRYTNIKTYEKTRIKLKVVQGNDYINASDIRLQIEGQSKAPSHFIACQGP 113
++ A+C +NR+ ++ Y+ R+ L+ + +DYINAS + EG S +A Q P
Sbjct: 22 IAIARCYSLKNRHQDVMPYDSNRVVLRSGK-DDYINASCV----EGLSPYCPPLVATQAP 76
Query: 114 LPNTWPQFWQMVYQQ 128
LP T FW MV++Q
Sbjct: 77 LPGTAADFWLMVHEQ 91
>CE27280 [T] KOG0789 Protein tyrosine phosphatase
Length = 352
Score = 48.5 bits (114), Expect = 2e-06
Identities = 30/90 (33%), Positives = 50/90 (55%), Gaps = 9/90 (10%)
Query: 46 RDSEWTFGVSDAKCNMTRNRYTNIKTYEKTRIKLKVVQGN--DYINASDIRLQIEGQSKA 103
+DS TF K NM +NRY+++ + TR+KL + + DYI+A+ ++ +
Sbjct: 74 QDSSLTFEAF--KQNMHKNRYSDVVCRDTTRVKLTIDKSRYEDYIHANYVKTNYLRNT-- 129
Query: 104 PSHFIACQGPLPNTWPQFWQMVYQQCPKKI 133
FI QGPL +T FW+M++Q+ + I
Sbjct: 130 ---FICTQGPLQHTIIDFWRMIFQERAESI 156
>Hs18375660 [T] KOG0789 Protein tyrosine phosphatase
Length = 399
Score = 47.4 bits (111), Expect = 6e-06
Identities = 29/76 (38%), Positives = 44/76 (57%), Gaps = 7/76 (9%)
Query: 56 DAKCNMTRNRYTNIKTYEKTRIKLKVVQGN---DYINASDIRLQIEGQSKAPSHFIACQG 112
D + +++RY I ++R+ L Q DYINA+ IR +G+ K +IA QG
Sbjct: 154 DIPGHASKDRYKTILPNPQSRVCLGRAQSQEDGDYINANYIR-GYDGKEKV---YIATQG 209
Query: 113 PLPNTWPQFWQMVYQQ 128
P+PNT FW+MV+Q+
Sbjct: 210 PMPNTVSDFWEMVWQE 225
>Hs18375658 [T] KOG0789 Protein tyrosine phosphatase
Length = 360
Score = 47.4 bits (111), Expect = 6e-06
Identities = 29/76 (38%), Positives = 44/76 (57%), Gaps = 7/76 (9%)
Query: 56 DAKCNMTRNRYTNIKTYEKTRIKLKVVQGN---DYINASDIRLQIEGQSKAPSHFIACQG 112
D + +++RY I ++R+ L Q DYINA+ IR +G+ K +IA QG
Sbjct: 115 DIPGHASKDRYKTILPNPQSRVCLGRAQSQEDGDYINANYIR-GYDGKEKV---YIATQG 170
Query: 113 PLPNTWPQFWQMVYQQ 128
P+PNT FW+MV+Q+
Sbjct: 171 PMPNTVSDFWEMVWQE 186
>Hs4506325 [T] KOG0789 Protein tyrosine phosphatase
Length = 657
Score = 46.6 bits (109), Expect = 9e-06
Identities = 30/71 (42%), Positives = 38/71 (53%), Gaps = 8/71 (11%)
Query: 62 TRNRYTNIKTYEKTRIKLKVVQGND----YINASDIRLQIEGQSKAPSHFIACQGPLPNT 117
T+NRY I +R+ L+ D YINA+ IR G S FIA QGP+ NT
Sbjct: 417 TKNRYKTILPNPLSRVCLRPKNVTDSLSTYINANYIR----GYSGKEKAFIATQGPMINT 472
Query: 118 WPQFWQMVYQQ 128
FWQMV+Q+
Sbjct: 473 VDDFWQMVWQE 483
>Hs19743917 [T] KOG0789 Protein tyrosine phosphatase
Length = 412
Score = 46.6 bits (109), Expect = 9e-06
Identities = 30/71 (42%), Positives = 38/71 (53%), Gaps = 8/71 (11%)
Query: 62 TRNRYTNIKTYEKTRIKLKVVQGND----YINASDIRLQIEGQSKAPSHFIACQGPLPNT 117
T+NRY I +R+ L+ D YINA+ IR G S FIA QGP+ NT
Sbjct: 172 TKNRYKTILPNPLSRVCLRPKNVTDSLSTYINANYIR----GYSGKEKAFIATQGPMINT 227
Query: 118 WPQFWQMVYQQ 128
FWQMV+Q+
Sbjct: 228 VDDFWQMVWQE 238
Database: KOG eukaryal database 04/03
Posted date: Apr 14, 2003 1:07 PM
Number of letters in database: 30,389,216
Number of sequences in database: 60,738
Lambda K H
0.321 0.136 0.423
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 8,547,322
Number of Sequences: 60738
Number of extensions: 335747
Number of successful extensions: 907
Number of sequences better than 1.0e-05: 87
Number of HSP's better than 0.0 without gapping: 3
Number of HSP's successfully gapped in prelim test: 84
Number of HSP's that attempted gapping in prelim test: 780
Number of HSP's gapped (non-prelim): 118
length of query: 136
length of database: 30,389,216
effective HSP length: 95
effective length of query: 41
effective length of database: 24,619,106
effective search space: 1009383346
effective search space used: 1009383346
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.9 bits)