ORF STATUS Function Best COG Functional category Pathways and functional systems
r_klactIV4742 good T KOG2197 Signal transduction mechanisms Ypt/Rab-specific GTPase-activating protein GYP7 and related proteins
Only best alignment is shown:
BLASTP 2.2.3 [May-13-2002]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= r_klactIV4742 1618994 1621219 742
(742 letters)
Database: KOG eukaryal database 04/03
60,738 sequences; 30,389,216 total letters
Searching..................................................done
Color Key for Alignment Scores: 
Score E
Sequences producing significant alignments: (bits) Value
YDL234c [T] KOG2197 Ypt/Rab-specific GTPase-activating protein G... 665 0.0
SPAC630.05 [T] KOG2197 Ypt/Rab-specific GTPase-activating protei... 391 e-108
HsM12232451 [T] KOG2197 Ypt/Rab-specific GTPase-activating prote... 210 7e-54
Hs21362084 [T] KOG2197 Ypt/Rab-specific GTPase-activating protei... 209 1e-53
At5g52590 [T] KOG2197 Ypt/Rab-specific GTPase-activating protein... 201 3e-51
7296240 [T] KOG2197 Ypt/Rab-specific GTPase-activating protein G... 190 8e-48
Hs13375952 [T] KOG2197 Ypt/Rab-specific GTPase-activating protei... 180 6e-45
CE14882 [T] KOG2197 Ypt/Rab-specific GTPase-activating protein G... 162 1e-39
Hs22062664 [TR] KOG2224 Uncharacterized conserved protein contai... 152 2e-36
CE29383 [TR] KOG2224 Uncharacterized conserved protein contains ... 146 1e-34
At5g54780 [T] KOG2197 Ypt/Rab-specific GTPase-activating protein... 120 1e-26
7297700 [TR] KOG2224 Uncharacterized conserved protein contains ... 115 2e-25
At5g41940 [T] KOG2197 Ypt/Rab-specific GTPase-activating protein... 115 3e-25
7295589_1 [R] KOG1648 Uncharacterized conserved protein contains... 110 1e-23
At3g49350 [T] KOG2197 Ypt/Rab-specific GTPase-activating protein... 109 2e-23
At5g53570 [T] KOG2197 Ypt/Rab-specific GTPase-activating protein... 108 4e-23
Hs14770789 [R] KOG1648 Uncharacterized conserved protein contain... 105 2e-22
At5g24390 [T] KOG2197 Ypt/Rab-specific GTPase-activating protein... 104 4e-22
Hs20548703_1 [T] KOG2197 Ypt/Rab-specific GTPase-activating prot... 103 1e-21
At4g28550 [T] KOG2197 Ypt/Rab-specific GTPase-activating protein... 94 1e-18
Hs22055332 [T] KOG2197 Ypt/Rab-specific GTPase-activating protei... 93 1e-18
CE00923 [R] KOG1648 Uncharacterized conserved protein contains R... 93 1e-18
At2g20440 [T] KOG2197 Ypt/Rab-specific GTPase-activating protein... 92 2e-18
At4g27100 [T] KOG2197 Ypt/Rab-specific GTPase-activating protein... 89 2e-17
At3g59570 [T] KOG2197 Ypt/Rab-specific GTPase-activating protein... 87 9e-17
At2g43490_1 [T] KOG2197 Ypt/Rab-specific GTPase-activating prote... 84 6e-16
7303082 [T] KOG2197 Ypt/Rab-specific GTPase-activating protein G... 73 1e-12
Hs21361637 [R] KOG4567 GTPase-activating protein 69 3e-11
SPBC530.01 [U] KOG1092 Ypt/Rab-specific GTPase-activating protei... 66 2e-10
7295061 [R] KOG4567 GTPase-activating protein 65 5e-10
At1g04830 [R] KOG4567 GTPase-activating protein 62 3e-09
7300700 [U] KOG1092 Ypt/Rab-specific GTPase-activating protein GYP1 60 1e-08
CE28759 [TR] KOG2223 Uncharacterized conserved protein contains ... 59 4e-08
At4g13730 [R] KOG4567 GTPase-activating protein 58 5e-08
At3g02460 [R] KOG1102 Rab6 GTPase activator GAPCenA and related ... 58 5e-08
Hs14733591 [TR] KOG2223 Uncharacterized conserved protein contai... 57 1e-07
ECU03g0560 [R] KOG4567 GTPase-activating protein 57 1e-07
At5g15930 [R] KOG1102 Rab6 GTPase activator GAPCenA and related ... 56 2e-07
Hs22056446 [U] KOG2058 Ypt/Rab GTPase activating protein 55 3e-07
Hs14745035 [TR] KOG2223 Uncharacterized conserved protein contai... 55 5e-07
7296688 [R] KOG4436 Predicted GTPase activator NB4S/EVI5 (contai... 54 9e-07
Hs8922167 [U] KOG2058 Ypt/Rab GTPase activating protein 53 2e-06
SPAC1952.17c [R] KOG4567 GTPase-activating protein 52 3e-06
At2g30710 [U] KOG1092 Ypt/Rab-specific GTPase-activating protein... 52 3e-06
ECU04g1530 [U] KOG1092 Ypt/Rab-specific GTPase-activating protei... 52 3e-06
7303241 [R] KOG1102 Rab6 GTPase activator GAPCenA and related TB... 52 4e-06
7300111 [U] KOG2058 Ypt/Rab GTPase activating protein 50 1e-05
>YDL234c [T] KOG2197 Ypt/Rab-specific GTPase-activating protein GYP7 and
related proteins
Length = 746
Score = 665 bits (1716), Expect = 0.0
Identities = 353/771 (45%), Positives = 509/771 (65%), Gaps = 54/771 (7%)
Query: 1 MSQILFCKSKVFIHPTSNRSDQLPGFLLVIKESQHTQTQDAKLSWIPENDLESSFVKTLL 60
MS+ILFCKSKVF+HPTS+ D + GFLL+ E+ Q A L +IPE+ L + + LL
Sbjct: 1 MSKILFCKSKVFLHPTSDARDNIAGFLLLTLEANKLSHQ-AILQYIPESGLSTLEISKLL 59
Query: 61 NVESKLLTAHS-----VRSPHDFT-VDSIYSSWSFTISISAIYSIQFKPPHPNGYWFGSC 114
E+K+ T + + + +F+ + + +F IS+S IY IQF+PP PNG++ GS
Sbjct: 60 KHEAKVGTCPTSTPFVIENSINFSNLVNTSLGQAFEISLSQIYCIQFRPPSPNGWYVGSL 119
Query: 115 IIN--CKNGMNEDIPVLFFHDDICTSTIAKRKKMSKEFDPFSNEGDIYWGGDDLRTCLQS 172
+I + PVLFFHD +C ST K K++ K +PF + ++YWGG DLR +
Sbjct: 120 VIYPLTEQFTGFQPPVLFFHDQLCPSTTDKLKRLRKSMNPFDDSDELYWGGVDLRNKINE 179
Query: 173 LVDLQKVDSSQCIYLVNASLDDLRNFSLNNFQRPQSGSSSKDDGN--------IWDSLEA 224
L++L+K + +LVN SL+DLRNF + +S ++SK D + + +
Sbjct: 180 LMELKKSNLEPEFWLVNPSLNDLRNFVSKDLL--ESYNNSKKDTTELATAGVKLNEKFQE 237
Query: 225 TRWSIMSKFADATTTASNLFGKLVKKHPIVQMIDKHSDNVYVKQLMKNPRVVEVQDEFDS 284
+W++MSK AD TT ++N + + +Q DN Y+++L+ N +V +++ ++DS
Sbjct: 238 WKWNVMSKIADVTTKSTNFIDSWLTNNSPIQK--SQIDNEYLQKLLNNEKVKQIEQDYDS 295
Query: 285 AKIYLAKWAMGVKQEAERYQKEHYLDDTYKRILRNELGISNDVEISPEELNIAVQRSFPL 344
A++YLA W++GVKQEAERYQK++ L D+Y+ + N+L +++ E+S E+N A+QR FPL
Sbjct: 296 ARVYLANWSLGVKQEAERYQKQNKLFDSYRNNIFNDLNLTD--ELSDTEINNALQRQFPL 353
Query: 345 TKQKWDSLFD-SQGRLSITVHEVKDFIFHGGVENDALRSEVWLFLLGVYPWDSSLQERKE 403
T+ KW+SL+D + GRL +TV+EVKDFIFHGG+END+LR +VW FLL +YPWDSS ER +
Sbjct: 354 TEAKWNSLWDENDGRLRVTVNEVKDFIFHGGLENDSLRGKVWGFLLEIYPWDSSQDERVQ 413
Query: 404 LKQAMEEDYNANYKSKWIYRDVL--DDSEEEEYWKDQVFRISKDVLRNDRDIPLYRHNTK 461
+ Q + +Y+ K W +D L DD +EEEYW DQ+FRISKDV R DR++ ++++NT
Sbjct: 414 IDQTLAAEYD-QLKLTWS-KDFLQFDDEDEEEYWNDQLFRISKDVRRCDRNLEIFQYNTI 471
Query: 462 DG----------KEDGAKNEEAPNKGDQEEEWEIKNPHLQALKNILISYNIYNPNLGYVQ 511
DG E+ + + E+ N + + ++NPHL L+NILI+YN+YN NLGYVQ
Sbjct: 472 DGLPPPPQQLPANENNSTSPESANDESDDADDGVRNPHLIHLQNILITYNVYNTNLGYVQ 531
Query: 512 GMTDLLSLIYFVLQDEALSFWCFVNFMNRMERNFLRDQSGIRDQMLTLVDLCQFMLPKFA 571
GMTDLLS IY ++++E +FWCF +FM+ MERNFLRDQSGI +QMLTLV+L Q MLP+ +
Sbjct: 532 GMTDLLSPIYVIMKEEWKTFWCFTHFMDIMERNFLRDQSGIHEQMLTLVELVQLMLPELS 591
Query: 572 EHLKKCESADLFFCFRMLLVWFKREFEFSDVCKIWEIFWTDYYSSQFQLFFMLAILQKHS 631
EHL KC+S +LFFCFRMLLVWFKREFE D+ IWE FWT YYSSQFQLFFMLAILQK+S
Sbjct: 592 EHLNKCDSGNLFFCFRMLLVWFKREFEMEDIMHIWENFWTFYYSSQFQLFFMLAILQKNS 651
Query: 632 DVVVSQLTEFDDVLKYFNDLRNSMDWSDIMIRSELLFIKFQKMIEVLEREEELISKRTTS 691
++ L +FD +LK+FN+L +DW+D+M+R+ELLF KF+KM+ V+ER+ + +S ++S
Sbjct: 652 QAILQHLNQFDQILKFFNELNGKLDWNDLMVRAELLFKKFEKMMHVMERDLQNVSSSSSS 711
Query: 692 TGYNGHEIPLTSEAEDPPLHHPXXXXXXXXXXXXXXXVIQKEGPRSKDSIK 742
+ +P SE +I+ EG RSK+S+K
Sbjct: 712 SSTG--VLPCQSE--------------RLTLLLSKKPIIRHEGQRSKNSVK 746
>SPAC630.05 [T] KOG2197 Ypt/Rab-specific GTPase-activating protein GYP7 and
related proteins
Length = 743
Score = 391 bits (1005), Expect = e-108
Identities = 235/706 (33%), Positives = 401/706 (56%), Gaps = 61/706 (8%)
Query: 4 ILFCKSKVFIHPTSNRSDQLPGFLLVIKE----SQHTQTQDAKLSWIPENDLESSFVKTL 59
+LF KSKVF+HPTS D + G+L + K + D LSW+P++ L++
Sbjct: 31 LLFSKSKVFVHPTSKMKDNISGYLSLSKSKALGNSSVAGSDILLSWVPDSFLKNRPRDLS 90
Query: 60 LNVESKLLTAHSVRSPHDFTVDSIYSSWSFTISISAIYSIQFKPPHPNGYWFGSCIINCK 119
+ ++ L+ S+R ++ + +SF++ + +IYSI F+PP G+ +GS +IN +
Sbjct: 91 VFQNAETLSNGSIR---EWVEIPQHLDYSFSVRLCSIYSIIFRPPR-YGWNYGSIVINLR 146
Query: 120 NGMNEDIPVLFFHDDICTSTIAKRKKMSKE-FDPFSNEGDIYWGGDDLRTCLQSLVDLQK 178
+ E +P LFFHDD C STI K+++++ FDPF G+++WGG L L+ L++
Sbjct: 147 DS-GESLPPLFFHDDECISTIEYGKQITRDRFDPFDESGNMFWGGTHLLMQLKKYASLEQ 205
Query: 179 VDSSQCIYLVNASLDD------------LRNFSLNNFQRPQSGSSSKDDGNIWD-SLEAT 225
+YLVN S +D + N LN+ P + SS N + +L
Sbjct: 206 SSHESQLYLVNPSPEDTVAFQSVELQKVISNNRLNSSSTPPTPRSSSSIFNPFRRALHDL 265
Query: 226 RWSIMSKFADATTTASNLFGKLVKKHPIVQMIDKHSDNVYVKQLMKNPRVVEVQDEFDSA 285
++++ +F+ T + +L++ H + + I H ++ L+++ RV ++ +E+D A
Sbjct: 266 SFTVLERFSRVTNYGKSEVDRLME-HKVTKSILPHLPRE-LQVLLESKRVQKLTEEYDPA 323
Query: 286 KIYLAKWAMGVKQEAERYQKEHYLDDTYKRILRNELGISNDVE------ISPEEL---NI 336
+++LA+WA G+ +++E + N G+ D + + P EL
Sbjct: 324 RMFLARWAEGIVEQSESNNSQPV----------NNAGVWTDAQREEDSSLGPFELVYIEE 373
Query: 337 AVQRSFPLTKQKWDSLFDSQGRLSITVHEVKDFIFHGGVENDALRSEVWLFLLGVYPWDS 396
V+R PL+ ++W+S+F++ G+L + VH V IFHGG++ +LR EVW FLL VYPWDS
Sbjct: 374 RVKRDDPLSVEQWNSMFNAHGKLQVDVHRVLGIIFHGGIQ-PSLRKEVWPFLLSVYPWDS 432
Query: 397 SLQERKELKQAMEEDYNANYKSKWIYRDVLDDSEEEEYWKDQVFRISKDVLRNDRDIPLY 456
+ +ER+ + +++E+Y K KW Y D+ + ++ +Q RI KDV R DR +
Sbjct: 433 TSEERRVIYLSLQEEY-CTLKRKW-YEDI-HKQFNDRWFIEQRNRIEKDVHRTDRQHEYF 489
Query: 457 RHNTKDGKEDGAKNEEAPNKGDQEEEWEIKNPHLQALKNILISYNIYNPNLGYVQGMTDL 516
+ E+ P+ D + + N +++ +K+IL++YN Y+ LGYVQGM+DL
Sbjct: 490 QI------------EDLPHP-DPQSTFTGTNMNMEMMKDILLTYNEYDTELGYVQGMSDL 536
Query: 517 LSLIYFVLQDEALSFWCFVNFMNRMERNFLRDQSGIRDQMLTLVDLCQFMLPKFAEHLKK 576
L+ IY D AL+FW V M R+ NFLRDQSG+ Q+ TL L +FM P+ HL+K
Sbjct: 537 LAPIYVTFNDNALTFWGMVGLMKRLHFNFLRDQSGMHRQLDTLRLLIEFMDPELFAHLEK 596
Query: 577 CESADLFFCFRMLLVWFKREFEFSDVCKIWEIFWTDYYSSQFQLFFMLAILQKHSDVVVS 636
+S++LF FRMLL++FKREF++ + K+W++ +T+Y S + +F AI ++H +V+++
Sbjct: 597 TDSSNLFCFFRMLLIYFKREFDWEVLLKLWDVLFTNYLSYDYHIFVAYAIAERHREVLLN 656
Query: 637 QLTEFDDVLKYFNDLRNSMDWSDIMIRSELLFIKFQKMIEVLEREE 682
Q + FD+VLKYFN+L + +I +E F +F+ + +++R++
Sbjct: 657 QTSAFDEVLKYFNELSGKLALEPTLICAEQCFYQFKNKLALIDRKQ 702
>HsM12232451 [T] KOG2197 Ypt/Rab-specific GTPase-activating protein GYP7 and
related proteins
Length = 674
Score = 210 bits (534), Expect = 7e-54
Identities = 114/349 (32%), Positives = 199/349 (56%), Gaps = 32/349 (9%)
Query: 338 VQRSFPLTKQKWDSLFDSQGRLSITVHEVKDFIFHGGVENDALRSEVWLFLLGVYPWDSS 397
VQR P++ ++W DS+GR+ + V +K IF GG+ + ALR + W FLLG +PWDS+
Sbjct: 294 VQRREPVSLEEWTKNIDSEGRI-LNVDNMKQMIFRGGLSH-ALRKQAWKFLLGYFPWDST 351
Query: 398 LQERKELKQAMEEDYNANYKSKWIYRDVLDDSEEEEY-WKDQVFRISKDVLRNDRDIPLY 456
+ER +L++ ++Y ++ K ++ + + E+ +D I KDV R DR Y
Sbjct: 352 KEERTQLQKQKTDEY---FRMKLQWKSISQEQEKRNSRLRDYRSLIEKDVNRTDRTNKFY 408
Query: 457 RHNTKDGKEDGAKNEEAPNKGDQEEEWEIKNPHLQALKNILISYNIYNPNLGYVQGMTDL 516
+G++ NP L L +IL++Y +Y+ +LGYVQGM+DL
Sbjct: 409 -----EGQD---------------------NPGLILLHDILMTYCMYDFDLGYVQGMSDL 442
Query: 517 LSLIYFVLQDEALSFWCFVNFMNRMERNFLRDQSGIRDQMLTLVDLCQFMLPKFAEHLKK 576
LS + +V+++E +FWCF ++M++M +NF G++ Q++ L L + + F +L+
Sbjct: 443 LSPLLYVMENEVDAFWCFASYMDQMHQNFEEQMQGMKTQLIQLSTLLRLLDSGFCSYLES 502
Query: 577 CESADLFFCFRMLLVWFKREFEFSDVCKIWEIFWTDYYSSQFQLFFMLAILQKHSDVVVS 636
+S L+FCFR LL+ FKREF F D+ ++WE+ WT+ + F L AIL+ ++
Sbjct: 503 QDSGYLYFCFRWLLIRFKREFSFLDILRLWEVMWTELPCTNFHLLLCCAILESEKQQIME 562
Query: 637 QLTEFDDVLKYFNDLRNSMDWSDIMIRSELLFIKFQKMIEVLEREEELI 685
+ F+++LK+ N+L +D DI+ ++E + ++ K E+ + E++
Sbjct: 563 KHYGFNEILKHINELSMKIDVEDILCKAEAISLQMVKCKELPQAVCEIL 611
>Hs21362084 [T] KOG2197 Ypt/Rab-specific GTPase-activating protein GYP7 and
related proteins
Length = 691
Score = 209 bits (532), Expect = 1e-53
Identities = 114/349 (32%), Positives = 199/349 (56%), Gaps = 32/349 (9%)
Query: 338 VQRSFPLTKQKWDSLFDSQGRLSITVHEVKDFIFHGGVENDALRSEVWLFLLGVYPWDSS 397
VQR P++ ++W DS+GR+ + V +K IF GG+ + ALR + W FLLG +PWDS+
Sbjct: 311 VQRREPVSLEEWTKNIDSEGRI-LNVDNMKQMIFRGGLSH-ALRKQAWKFLLGYFPWDST 368
Query: 398 LQERKELKQAMEEDYNANYKSKWIYRDVLDDSEEEEY-WKDQVFRISKDVLRNDRDIPLY 456
+ER +L++ ++Y ++ K ++ + + E+ +D I KDV R DR Y
Sbjct: 369 KEERTQLQKQKTDEY---FRMKLQWKSISQEQEKRNSRLRDYRSLIEKDVNRTDRTNKFY 425
Query: 457 RHNTKDGKEDGAKNEEAPNKGDQEEEWEIKNPHLQALKNILISYNIYNPNLGYVQGMTDL 516
+G++ NP L L +IL++Y +Y+ +LGYVQGM+DL
Sbjct: 426 -----EGQD---------------------NPGLILLHDILMTYCMYDFDLGYVQGMSDL 459
Query: 517 LSLIYFVLQDEALSFWCFVNFMNRMERNFLRDQSGIRDQMLTLVDLCQFMLPKFAEHLKK 576
LS + +V+++E +FWCF ++M++M +NF G++ Q++ L L + + F +L+
Sbjct: 460 LSPLLYVMENEVDAFWCFASYMDQMHQNFEEQMQGMKTQLIQLSTLLRLLDSGFCSYLES 519
Query: 577 CESADLFFCFRMLLVWFKREFEFSDVCKIWEIFWTDYYSSQFQLFFMLAILQKHSDVVVS 636
+S L+FCFR LL+ FKREF F D+ ++WE+ WT+ + F L AIL+ ++
Sbjct: 520 QDSGYLYFCFRWLLIRFKREFGFLDILRLWEVMWTELPCTNFHLLLCCAILESEKQQIME 579
Query: 637 QLTEFDDVLKYFNDLRNSMDWSDIMIRSELLFIKFQKMIEVLEREEELI 685
+ F+++LK+ N+L +D DI+ ++E + ++ K E+ + E++
Sbjct: 580 KHYGFNEILKHINELSMKIDVEDILCKAEAISLQMVKCKELPQAVCEIL 628
>At5g52590 [T] KOG2197 Ypt/Rab-specific GTPase-activating protein GYP7 and
related proteins
Length = 338
Score = 201 bits (512), Expect = 3e-51
Identities = 111/333 (33%), Positives = 187/333 (55%), Gaps = 34/333 (10%)
Query: 340 RSFPLTKQKWDSLFDSQGRLSITVHEVKDFIFHGGVENDALRSEVWLFLLGVYPWDSSLQ 399
R P+ +++ +L DS+GR+ + +++ +F+GG+E+ LR EVW FLLG Y +DS+
Sbjct: 6 RQPPMGHKEFTALLDSEGRV-VESKALRERVFYGGIEHQ-LRREVWPFLLGYYAYDSTYA 63
Query: 400 ERKELKQAMEEDYNANYKSKWIYRDVLDDSEEEEY--WKDQVFRISKDVLRNDRDIPLYR 457
ER+ L+ +Y A K +W + + + + ++++ I KDV+R DR Y
Sbjct: 64 EREYLRSVKRMEY-ATLKQQW---QSISPEQAKRFTKYRERKGLIDKDVVRTDRAFEYY- 118
Query: 458 HNTKDGKEDGAKNEEAPNKGDQEEEWEIKNPHLQALKNILISYNIYNPNLGYVQGMTDLL 517
+GD N H+ ++++IL++Y+ YN +LGY QGM+D L
Sbjct: 119 ------------------EGDD-------NLHVNSMRDILLTYSFYNFDLGYCQGMSDYL 153
Query: 518 SLIYFVLQDEALSFWCFVNFMNRMERNFLRDQSGIRDQMLTLVDLCQFMLPKFAEHLKKC 577
S I FV++DE+ SFWCFV M R+ NF RDQ+G+ Q+ L L + + + K+
Sbjct: 154 SPILFVMEDESESFWCFVALMERLGPNFNRDQNGMHTQLFALSKLVELLDSPLHNYFKEN 213
Query: 578 ESADLFFCFRMLLVWFKREFEFSDVCKIWEIFWTDYYSSQFQLFFMLAILQKHSDVVVSQ 637
+ + FFCFR +L+ FKREFE+ ++WE+ WT Y S F L+ +A+L++ ++ +
Sbjct: 214 DCLNYFFCFRWILIQFKREFEYEKTMQLWEVMWTHYLSEHFHLYVCVAVLKRCRSKIMGE 273
Query: 638 LTEFDDVLKYFNDLRNSMDWSDIMIRSELLFIK 670
+FD +LK+ N+L +D + +E L I+
Sbjct: 274 QMDFDTLLKFINELSGHIDLDSTVRDAEALCIE 306
>7296240 [T] KOG2197 Ypt/Rab-specific GTPase-activating protein GYP7 and
related proteins
Length = 715
Score = 190 bits (482), Expect = 8e-48
Identities = 112/337 (33%), Positives = 182/337 (53%), Gaps = 34/337 (10%)
Query: 338 VQRSFPLTKQKWDSLFDSQGRLSITVHEVKDFIFHGGVENDALRSEVWLFLLGVYPWDSS 397
V+R PLT+ +W GR+S + +K+ IF GGV +LR EVW FLL Y W +
Sbjct: 337 VERGHPLTETQWLEFQTPDGRISDSAR-IKELIFRGGVVQ-SLRPEVWKFLLNYYLWSDT 394
Query: 398 LQERKELKQAMEEDYNANYKSKWIYRDVLDDSEEEEY--WKDQVFRISKDVLRNDRDIPL 455
ER E ++ +Y N K++W+ + ++E + ++++ +I KDV R DR +
Sbjct: 395 HVERIERRKQKSIEY-YNMKAQWL---AMTTTQEANFCGYRERKCQIEKDVKRTDRSLQF 450
Query: 456 YRHNTKDGKEDGAKNEEAPNKGDQEEEWEIKNPHLQALKNILISYNIYNPNLGYVQGMTD 515
+ ED NP+L L+ IL++Y +YN +LGYVQGM+D
Sbjct: 451 F------AGED--------------------NPNLTLLQGILMTYVMYNFDLGYVQGMSD 484
Query: 516 LLSLIYFVLQDEALSFWCFVNFMNRMERNFLRDQSGIRDQMLTLVDLCQFMLPKFAEHLK 575
LL+ I + +E +FWCFV FM + NF DQ+G++ Q + L +F +++
Sbjct: 485 LLAPILEIQVNEVDTFWCFVGFMELVFTNFDIDQAGMKTQFAQIRRLIEFANAPLFNYMR 544
Query: 576 KCESADLFFCFRMLLVWFKREFEFSDVCKIWEIFWTDYYSSQFQLFFMLAILQKHSDVVV 635
+S +++FCFR LLVW+KRE DV K+WE WT F L F +AIL + + V++
Sbjct: 545 SHDSDNMYFCFRWLLVWYKRELNSEDVLKLWECLWTRLPCPNFHLLFSVAILDQETRVII 604
Query: 636 SQLTEFDDVLKYFNDLRNSMDWSDIMIRSELLFIKFQ 672
EF ++LK+ N+L ++D + +E ++++ +
Sbjct: 605 DSQYEFTEILKHVNELSGNIDVQKTLQVAEGIYLQLK 641
>Hs13375952 [T] KOG2197 Ypt/Rab-specific GTPase-activating protein GYP7 and
related proteins
Length = 648
Score = 180 bits (457), Expect = 6e-45
Identities = 115/360 (31%), Positives = 181/360 (49%), Gaps = 35/360 (9%)
Query: 327 VEISPEELNIAVQRSFPLTKQKWDSLFDSQGRLSITVHEVKDFIFHGGVENDALRSEVWL 386
VE+ P V+R P+T+++W +GRL V E+K+ IF GG+ + +LR E W
Sbjct: 267 VELGPRP---TVERGPPVTEEEWARHVGPEGRLQ-QVPELKNRIFSGGL-SPSLRREAWK 321
Query: 387 FLLGVYPWDSSLQERKELKQAMEEDYNANYKSKWIYRDVLDDSEEEE-YWKDQVFRISKD 445
FLLG W+ + +E K + ++Y ++ K ++ V + E I +D
Sbjct: 322 FLLGYLSWEGTAEEHKAHIRKKTDEY---FRMKLQWKSVSPEQERRNSLLHGYRSLIERD 378
Query: 446 VLRNDRDIPLYRHNTKDGKEDGAKNEEAPNKGDQEEEWEIKNPHLQALKNILISYNIYNP 505
V R DR Y E P +NP L L +IL++Y +Y+
Sbjct: 379 VSRTDRTNKFY---------------EGP-----------ENPGLGLLNDILLTYCMYHF 412
Query: 506 NLGYVQGMTDLLSLIYFVLQDEALSFWCFVNFMNRMERNFLRDQSGIRDQMLTLVDLCQF 565
+LGYVQGM+DLLS I +V+Q+E +FWCF FM ++ NF Q ++ Q+ L+ L +
Sbjct: 413 DLGYVQGMSDLLSPILYVIQNEVDAFWCFCGFMELVQGNFEESQETMKRQLGRLLLLLRV 472
Query: 566 MLPKFAEHLKKCESADLFFCFRMLLVWFKREFEFSDVCKIWEIFWTDYYSSQFQLFFMLA 625
+ P + L +S L FCFR LL+WFKREF F DV ++WE+ WT L A
Sbjct: 473 LDPLLCDFLDSQDSGSLCFCFRWLLIWFKREFPFPDVLRLWEVLWTGLPGPNLHLLVACA 532
Query: 626 ILQKHSDVVVSQLTEFDDVLKYFNDLRNSMDWSDIMIRSELLFIKFQKMIEVLEREEELI 685
IL D ++ +++LK+ N+L + D++ R+E L + E+ +E++
Sbjct: 533 ILDMERDTLMLSGFGSNEILKHINELTMKLSVEDVLTRAEALHRQLTACPELPHNVQEIL 592
>CE14882 [T] KOG2197 Ypt/Rab-specific GTPase-activating protein GYP7 and
related proteins
Length = 619
Score = 162 bits (411), Expect = 1e-39
Identities = 84/225 (37%), Positives = 127/225 (56%), Gaps = 26/225 (11%)
Query: 444 KDVLRNDRDIPLYRHNTKDGKEDGAKNEEAPNKGDQEEEWEIKNPHLQALKNILISYNIY 503
KDV R DR +P ++ GD N +L L N+L++Y +Y
Sbjct: 11 KDVARTDRTVPFFQ-------------------GDD-------NVNLVHLHNVLMTYVMY 44
Query: 504 NPNLGYVQGMTDLLSLIYFVLQDEALSFWCFVNFMNRMERNFLRDQSGIRDQMLTLVDLC 563
N +LGYVQGM+D S + FV++DE +FWCFV M ++NF DQ+ I+ QM L DL
Sbjct: 45 NFDLGYVQGMSDFASPLLFVMKDEVDTFWCFVGLMELTQKNFETDQAFIKLQMNQLRDLV 104
Query: 564 QFMLPKFAEHLKKCESADLFFCFRMLLVWFKREFEFSDVCKIWEIFWTDYYSSQFQLFFM 623
+ PK A +L+ +S D++FCFR +LVWFKREF F D CK+WE+ W+ +F L
Sbjct: 105 MIINPKLANYLESEKSDDMYFCFRWVLVWFKREFSFLDTCKLWEVLWSGQPCPRFLLLIC 164
Query: 624 LAILQKHSDVVVSQLTEFDDVLKYFNDLRNSMDWSDIMIRSELLF 668
+AIL +++++ ++LK+ NDL + +I+ +E +F
Sbjct: 165 VAILDSQTNIIIDNQFGLTEILKHINDLSMHLKVDEILTAAEAIF 209
>Hs22062664 [TR] KOG2224 Uncharacterized conserved protein contains TBC domain
Length = 766
Score = 152 bits (383), Expect = 2e-36
Identities = 94/312 (30%), Positives = 165/312 (52%), Gaps = 35/312 (11%)
Query: 364 HEVKDFIFHGGVENDALRSEVWLFLLGVYPWDSSLQERKELKQAMEEDYNANYKSKWIYR 423
++++ IF GG++ ++R EVW FLL Y +S+ +ER+ L+ ++Y+ + R
Sbjct: 414 YKLRKAIFFGGIDV-SIRGEVWPFLLRYYSHESTSEEREALRLQKRKEYSEIQQK----R 468
Query: 424 DVLDDSEEEEYWKDQVFRISKDVLRNDRDIPLYRHNTKDGKEDGAKNEEAPNKGDQEEEW 483
+ E +W++ F + KDV+R DR+ +R ED
Sbjct: 469 LSMTPEEHRAFWRNVQFTVDKDVVRTDRNNQFFRG------ED----------------- 505
Query: 484 EIKNPHLQALKNILISYNIYNPNLGYVQGMTDLLSLIYFVLQDEALSFWCFVNFM-NRME 542
NP++++++ IL++Y +YNP +GY QGM+DL++ I + DE+ +FWCFV M N +
Sbjct: 506 ---NPNVESMRRILLNYAVYNPAVGYSQGMSDLVAPILAEVLDESDTFWCFVGLMQNTIF 562
Query: 543 RNFLRDQSGIRDQMLTLVDLCQFMLPKFAEHLKKC--ESADLFFCFRMLLVWFKREFEFS 600
+ RD+ + Q+L L +L + +F +HL + + FC R LL+ FKREF +
Sbjct: 563 VSSPRDED-MEKQLLYLRELLRLTHVRFYQHLVSLGEDGLQMLFCHRWLLLCFKREFPEA 621
Query: 601 DVCKIWEIFWTDYYSSQFQLFFMLAILQKHSDVVVSQLTEFDDVLKYFNDLRNSMDWSDI 660
+ +IWE W Y + F LF +AI+ + D V+ Q D +L +F +L M+ +
Sbjct: 622 EALRIWEACWAHYQTDYFHLFICVAIVAIYGDDVIEQQLATDQMLLHFGNLAMHMNGELV 681
Query: 661 MIRSELLFIKFQ 672
+ ++ L +F+
Sbjct: 682 LRKARSLLYQFR 693
>CE29383 [TR] KOG2224 Uncharacterized conserved protein contains TBC domain
Length = 759
Score = 146 bits (369), Expect = 1e-34
Identities = 103/340 (30%), Positives = 174/340 (50%), Gaps = 41/340 (12%)
Query: 344 LTKQKWDSLFDSQGRLSITVHEVKDFIFHGGVENDALRSEVWLFLLGVYPWDSSLQERKE 403
+T W S ++++ + I V+ IF ++ + +R +VW FLL VYPW+SS +R+
Sbjct: 416 ITLNTWRS-YENKSGVIIDSGTVRKHIFFASMDVE-MREKVWPFLLRVYPWESSADQREN 473
Query: 404 LKQAMEEDYNANYKSKWIYRDVLDDSEEEEYWKDQVFRISKDVLRNDRDIPLYRHNTKDG 463
+K + +Y K + YR V ++++ W I KDV+R DR P +
Sbjct: 474 IKNDLFLEYQNIRKRR--YR-VTENAQAR--WISIENSIVKDVVRTDRKNPFFA------ 522
Query: 464 KEDGAKNEEAPNKGDQEEEWEIKNPHLQALKNILISYNIYNPNLGYVQGMTDLLSLIYFV 523
GD NP+ + +KNIL++Y + P++ Y+QGM+DLL+ +
Sbjct: 523 -------------GDN-------NPNSEIMKNILLNYAVMYPDINYIQGMSDLLAPLLST 562
Query: 524 LQDEALSFWCFVNFMNRMERNFLRDQSGIRDQMLT----LVDLCQFMLPKFAEHLKKC-- 577
L+DE S++CF NFM + F G + M T L ++ + +P F EHL+K
Sbjct: 563 LKDEVDSYFCFKNFMQQTV--FSSTPQGNENLMETNLTYLRNMLRMFVPDFYEHLEKQRP 620
Query: 578 ESADLFFCFRMLLVWFKREFEFSDVCKIWEIFWTDYYSSQFQLFFMLAILQKHSDVVVSQ 637
++ L F R +L+ FKREF + IWE W Y ++ F LF +AI+ + V++Q
Sbjct: 621 DAMQLMFVHRWILLCFKREFPENYALHIWECCWAHYRTNYFHLFVCVAIVSIYGKDVLTQ 680
Query: 638 LTEFDDVLKYFNDLRNSMDWSDIMIRSELLFIKFQKMIEV 677
D++L +F L N MD + ++ ++ L +F +M ++
Sbjct: 681 DLPHDEILLFFASLANHMDATLVLQKARGLLFEFTRMEKI 720
>At5g54780 [T] KOG2197 Ypt/Rab-specific GTPase-activating protein GYP7 and
related proteins
Length = 435
Score = 120 bits (300), Expect = 1e-26
Identities = 105/409 (25%), Positives = 175/409 (42%), Gaps = 90/409 (22%)
Query: 344 LTKQKWDSLFDSQGRLSITVHEVKDFIFHGGVENDALRSEVWLFLLGVYPWDSSLQERKE 403
L+ +KW + F ++G L I + I GG+ + ++R EVW FLLG Y S+ +ER++
Sbjct: 35 LSVRKWQAAFTTEGFLDIG--KTLSRIQRGGI-HPSIRGEVWEFLLGCYDPKSTFEEREQ 91
Query: 404 LKQAMEEDYNANYKSK------------WIYRDVLDDSEEEEYWKDQVFRISKDVLRNDR 451
++Q Y A++K + +I V+ + E Y D + ++ N
Sbjct: 92 IRQRRRLQY-ASWKEECKQMFPVIGSGGFITAPVITNKGEPIY--DPIVLQETNLGANGS 148
Query: 452 DIPLYRHNTKDGKEDGAKNEEA-------------PNKGDQEEEWEIKNPHLQALKNILI 498
D KD G +++ N+ D+ + K +L L +IL
Sbjct: 149 DF------FKDLASRGPLDQKVIQWLLTLHQIGLDVNRTDRTLVFYEKKENLSKLWDILA 202
Query: 499 SYNIYNPNLGYVQGMTDLLSLIYFVLQDEALSFWCFVNFMNRMERNFLRDQS---GIRDQ 555
Y + ++GY QGM+DL S + +L+DEA +FWCF M R+ NF RD G+ Q
Sbjct: 203 LYAWIDNDVGYCQGMSDLCSPMIMLLEDEADAFWCFERLMRRLRGNF-RDTGRSVGVEAQ 261
Query: 556 MLTLVDLCQFMLPKFAEHLKKCESADLFFCFRMLLVWFKREFEFSDVCKIWEIFW----- 610
+ L + Q + PK HL+K D F RM++V F+REF F D +WE+ W
Sbjct: 262 LTHLASITQIIDPKLHHHLEKLGGGDYLFAIRMIMVQFRREFSFCDSLYLWEMMWALEYD 321
Query: 611 ----TDYYSSQFQ----------------------------------------LFFMLAI 626
+ Y QF+ +F + ++
Sbjct: 322 PEMYSLYEEPQFEGERIEGSSKGKPKSINQCGKYERENMKNGGKSAEGPLPISVFLVASV 381
Query: 627 LQKHSDVVVSQLTEFDDVLKYFNDLRNSMDWSDIMIRSELLFIKFQKMI 675
L+ S ++++ DDV+K ND+ ++D + L K+ K +
Sbjct: 382 LKDKSSKLMTEARGLDDVVKILNDITGNLDAKKACTGAMKLHKKYLKKV 430
>7297700 [TR] KOG2224 Uncharacterized conserved protein contains TBC domain
Length = 674
Score = 115 bits (289), Expect = 2e-25
Identities = 86/309 (27%), Positives = 148/309 (47%), Gaps = 59/309 (19%)
Query: 370 IFHGGVENDALRSEVWLFLLGVYPWDSSLQERKELKQAMEEDYNANYKSKWIYRDVLDDS 429
+F GG+E +LR VW FLL Y + S+ ++R L ++Y K +Y +
Sbjct: 384 VFFGGLEK-SLRKTVWPFLLKCYSFSSTFEDRAVLMDIKRQEYE-EITRKRLYS--MSPE 439
Query: 430 EEEEYWKDQVFRISKDVLRNDRDIPLYRHNTKDGKEDGAKNEEAPNKGDQEEEWEIKNPH 489
++ +WK + KDV+R DR P + GD NP+
Sbjct: 440 QQIHFWKTVQIVVEKDVVRTDRTNPFFC-------------------GDD-------NPN 473
Query: 490 LQALKNILISYNIYNPNLGYVQGMTDLLSLIYFVLQDEALSFWCFVNFMNRMERNFLRDQ 549
+ +KNIL+++ +YN + Y Q +FV +R+ +
Sbjct: 474 TEVMKNILLNFAVYNTGMSYSQRA-------FFVCTPT--------------DRDVDHNL 512
Query: 550 SGIRDQMLTLVDLCQFMLPKFAEHLKKC-ESADLFFCFRMLLVWFKREFEFSDVCKIWEI 608
S +R+ L + MLP F +HL++ +S +L FC R LL+ FKREF + V ++WE
Sbjct: 513 SYLRE-------LIRIMLPHFYKHLEQHNDSMELLFCHRWLLLCFKREFTEAVVIRMWEA 565
Query: 609 FWTDYYSSQFQLFFMLAILQKHSDVVVSQLTEFDDVLKYFNDLRNSMDWSDIMIRSELLF 668
W++Y + F LF LAI+ ++D VV+Q D++L +F+ L MD I+ ++ L
Sbjct: 566 CWSNYLTDYFHLFLCLAIIAVYADDVVAQNLRPDEMLLHFSSLAMYMDGQLILRKARGLL 625
Query: 669 IKFQKMIEV 677
+++++ ++
Sbjct: 626 HQYRQLPKI 634
>At5g41940 [T] KOG2197 Ypt/Rab-specific GTPase-activating protein GYP7 and
related proteins
Length = 506
Score = 115 bits (287), Expect = 3e-25
Identities = 57/188 (30%), Positives = 96/188 (50%), Gaps = 20/188 (10%)
Query: 489 HLQALKNILISYNIYNPNLGYVQGMTDLLSLIYFVLQDEALSFWCFVNFMNRMERNFLRD 548
H L IL +Y +Y+P +GY QGM+DLLS + V++D+ L+FWCFV FM++ NF D
Sbjct: 300 HAARLVGILEAYAVYDPEIGYCQGMSDLLSPLIAVMEDDVLAFWCFVGFMSKARHNFRLD 359
Query: 549 QSGIRDQMLTLVDLCQFMLPKFAEHLKKCESADLFFCFRMLLVWFKREFEFSDVCKIWEI 608
+ GIR Q+ + + +F HL+ E+ D FF +RM++V F+RE F +WE+
Sbjct: 360 EVGIRRQLSMVSKIIKFKDIHLYRHLENLEAEDCFFVYRMVVVLFRRELTFEQTLCLWEV 419
Query: 609 FWTDYY--------------------SSQFQLFFMLAILQKHSDVVVSQLTEFDDVLKYF 648
W D + L+ + A + + ++ + + D+++K
Sbjct: 420 MWADQAAIRTGIAKATWGRIRLRAPPTEDLLLYAIAASVLQRRKTIIEKYSGMDEIMKEC 479
Query: 649 NDLRNSMD 656
N + +D
Sbjct: 480 NSMAGHLD 487
>7295589_1 [R] KOG1648 Uncharacterized conserved protein contains RUN BRK and
TBC domains
Length = 1300
Score = 110 bits (274), Expect = 1e-23
Identities = 60/200 (30%), Positives = 105/200 (52%), Gaps = 10/200 (5%)
Query: 483 WEIKNPHLQALKNILISYNIYNPNLGYVQGMTDLLSLIYFVLQDEALSFWCFVNFMNRME 542
W N +L L+N++ +Y + ++GY+QGM DL++ + + DE+LS+ CF M RM
Sbjct: 1043 WYFANENLDKLRNVISTYVWEHLDVGYMQGMCDLVAPLLVIFDDESLSYSCFCKLMERMI 1102
Query: 543 RNFLRDQSGIRD----QMLTLVDLCQFMLPKFAEHLKKCESADLFFCFRMLLVWFKREFE 598
NF G D M +L+ + + + + +FC+R L+ FKRE
Sbjct: 1103 ENF--PSGGAMDMHFANMRSLIQILDSEMYDLMD--SNGDYTHFYFCYRWFLLDFKRELV 1158
Query: 599 FSDVCKIWEIFWTDYY--SSQFQLFFMLAILQKHSDVVVSQLTEFDDVLKYFNDLRNSMD 656
+ DV WE+ W + S F LF LA+L+ + D+++S +F DV+K+FN++ +
Sbjct: 1159 YDDVFATWEVIWAAKHIASGHFVLFLALALLETYRDIILSNSMDFTDVIKFFNEMAERHN 1218
Query: 657 WSDIMIRSELLFIKFQKMIE 676
++ + L ++ Q +IE
Sbjct: 1219 AQSVLQLARSLVLQLQMIIE 1238
>At3g49350 [T] KOG2197 Ypt/Rab-specific GTPase-activating protein GYP7 and
related proteins
Length = 554
Score = 109 bits (272), Expect = 2e-23
Identities = 66/219 (30%), Positives = 106/219 (48%), Gaps = 3/219 (1%)
Query: 395 DSSLQERKELKQAMEEDYNANYKSKWIYRDVLDDSEEEEYWKDQVFRISKDVLRNDRDIP 454
DS + E+ Q + + S + + +EE+ ++ R+ D +R D +
Sbjct: 250 DSDSSDESEVVQVFQSSATPDVNSTYPASSSIPRTEEDFVTWQRIIRL--DAVRADSEWT 307
Query: 455 LYRHNTKDGKEDGA-KNEEAPNKGDQEEEWEIKNPHLQALKNILISYNIYNPNLGYVQGM 513
Y + ED A + EA D K L +L +Y +Y+P++GY QGM
Sbjct: 308 SYSPSQAVISEDRACRAAEAVGLKDYNHLEPYKIFQAARLVAVLEAYALYDPDIGYCQGM 367
Query: 514 TDLLSLIYFVLQDEALSFWCFVNFMNRMERNFLRDQSGIRDQMLTLVDLCQFMLPKFAEH 573
+DLLS I V+ D+ FWCFV FM + NF D+ GIR Q+ + + + + H
Sbjct: 368 SDLLSPILSVIPDDHEVFWCFVGFMKKARHNFRLDEVGIRRQLNIVSKIIKSKDSQLYRH 427
Query: 574 LKKCESADLFFCFRMLLVWFKREFEFSDVCKIWEIFWTD 612
L+K ++ D FF +RM++V F+RE +WE+ W D
Sbjct: 428 LEKLQAEDCFFVYRMVVVMFRRELTLDQTLCLWEVMWAD 466
>At5g53570 [T] KOG2197 Ypt/Rab-specific GTPase-activating protein GYP7 and
related proteins
Length = 550
Score = 108 bits (269), Expect = 4e-23
Identities = 65/263 (24%), Positives = 123/263 (46%), Gaps = 20/263 (7%)
Query: 442 ISKDVLRNDRDIPLYR-HNTKDGKEDGAKNEEAPNKGDQEEEWEIKNPHLQALKNILISY 500
I D LR D + Y ++T + + E+ D + + H L IL +Y
Sbjct: 288 IRLDALRADSEWANYSPYSTAITESKARRLAESVGLKDYDHLESCRLYHAARLVAILEAY 347
Query: 501 NIYNPNLGYVQGMTDLLSLIYFVLQDEALSFWCFVNFMNRMERNFLRDQSGIRDQMLTLV 560
+Y+P +GY QGM+DLLS I V+ ++ +FWCFV FM + NF D++GI+ Q+ +
Sbjct: 348 AMYDPEIGYCQGMSDLLSPILAVISEDHEAFWCFVGFMKKARHNFRLDEAGIQRQLSIVS 407
Query: 561 DLCQFMLPKFAEHLKKCESADLFFCFRMLLVWFKREFEFSDVCKIWEIFWTDYYS----- 615
+ + + +HL+ ++ D F +RM+LV F+RE F +WE+ W D +
Sbjct: 408 KIIKNKDSQLYKHLENLQAEDCSFVYRMVLVMFRRELSFEQTLCLWEVMWADQAAIRAGV 467
Query: 616 --------------SQFQLFFMLAILQKHSDVVVSQLTEFDDVLKYFNDLRNSMDWSDIM 661
+ L + +A L +++ + + D++++ N + ++ ++
Sbjct: 468 GKSPWSRIRQQAPPTDDLLLYAIAALVLRRKLIIQKYSSMDEIVEECNSMAGQLNVWKLL 527
Query: 662 IRSELLFIKFQKMIEVLEREEEL 684
+ L + IE L + + +
Sbjct: 528 DDAHHLVVTLHDKIETLSQSQSI 550
>Hs14770789 [R] KOG1648 Uncharacterized conserved protein contains RUN BRK and
TBC domains
Length = 1006
Score = 105 bits (263), Expect = 2e-22
Identities = 60/198 (30%), Positives = 106/198 (53%), Gaps = 6/198 (3%)
Query: 483 WEIKNPHLQALKNILISYNIYNPNLGYVQGMTDLLSLIYFVLQDEALSFWCFVNFMNRME 542
W P+L+ L++++ SY + ++GYVQGM DLL+ + L ++ L++ CF + M RM
Sbjct: 809 WYFTPPNLERLRDVMCSYVWEHLDVGYVQGMCDLLAPLLVTLDNDQLAYSCFSHLMKRMS 868
Query: 543 RNFLRDQSGIRD-QMLTLVDLCQFMLPKFAEHL-KKCESADLFFCFRMLLVWFKREFEFS 600
+NF G D + L Q + + E + + + +FC+R L+ FKRE +
Sbjct: 869 QNF--PNGGAMDTHFANMRSLIQILDSELFELMHQNGDYTHFYFCYRWFLLDFKRELLYE 926
Query: 601 DVCKIWEIFWTDYY--SSQFQLFFMLAILQKHSDVVVSQLTEFDDVLKYFNDLRNSMDWS 658
DV +WE+ W + S F LF LA+++ + +++ +F D++K+FN+ D
Sbjct: 927 DVFAVWEVIWAARHISSEHFVLFIALALVEAYREIIRDNNMDFTDIIKFFNERAEHHDAQ 986
Query: 659 DIMIRSELLFIKFQKMIE 676
+I+ + L K Q +IE
Sbjct: 987 EILRIARDLVHKVQMLIE 1004
>At5g24390 [T] KOG2197 Ypt/Rab-specific GTPase-activating protein GYP7 and
related proteins
Length = 528
Score = 104 bits (260), Expect = 4e-22
Identities = 67/257 (26%), Positives = 119/257 (46%), Gaps = 22/257 (8%)
Query: 442 ISKDVLRNDRDIPLYRHNTKDGKEDGAKNE-EAPNKGDQEEEWEIKNPHLQALKNILISY 500
I D LR D + Y + E+ A+ EA D K H L +L +Y
Sbjct: 267 IRLDALRADTEWTPYSQSQALVSENRARRAAEAVGLKDYSYLEPSKIFHAARLVAVLEAY 326
Query: 501 NIYNPNLGYVQGMTDLLSLIYFVLQDEALSFWCFVNFMNRMERNFLRDQSGIRDQMLTLV 560
+++P +GY QGM+DLLS I V+ D+ +FWCFV FM + +NF D+ GI Q+ +
Sbjct: 327 ALHDPEIGYCQGMSDLLSPILSVIPDDYEAFWCFVGFMKKARQNFRVDEVGITRQLNIVS 386
Query: 561 DLCQFMLPKFAEHLKKCESADLFFCFRMLLVWFKREFEFSDVCKIWEIFWTDYY------ 614
+ + + +HL+K ++ D FF +RM+LV F+RE +WE+ W D
Sbjct: 387 KIIKSKDSQLYKHLEKVKAEDCFFVYRMVLVMFRRELTLEQTLHLWEVIWADQAAIRAGM 446
Query: 615 ---------------SSQFQLFFMLAILQKHSDVVVSQLTEFDDVLKYFNDLRNSMDWSD 659
+ L+ + A + + V++ + + +++L+ +++ +D
Sbjct: 447 GKSSWSRRIKQRAPPTEDLLLYVVAASVLQRRKVIIEKYSSMEEILRECHNMVGKLDVWK 506
Query: 660 IMIRSELLFIKFQKMIE 676
++ + L + IE
Sbjct: 507 LLDDAHDLIVTLHAKIE 523
>Hs20548703_1 [T] KOG2197 Ypt/Rab-specific GTPase-activating protein GYP7 and
related proteins
Length = 213
Score = 103 bits (257), Expect = 1e-21
Identities = 67/195 (34%), Positives = 97/195 (49%), Gaps = 31/195 (15%)
Query: 417 KSKWIYRDVLDDSEEEEYWKDQVFRISKDVLRNDRDIPLYRHNTKDGKEDGAKNEEAPNK 476
KS+W R + E+ E+ + V KDVLR DR P Y G EDG
Sbjct: 15 KSEWAQRA---NPEDLEFIRSTVL---KDVLRTDRAHPYYA-----GPEDG--------- 54
Query: 477 GDQEEEWEIKNPHLQALKNILISYNIYNPNLGYVQGMTDLLSLIYFVLQDEALSFWCFVN 536
PHL+AL ++L +Y + +P + Y QGM+DL S I V+ E +F CF
Sbjct: 55 -----------PHLRALHDLLTTYAVTHPQVSYCQGMSDLASPILAVMDHEGHAFVCFCG 103
Query: 537 FMNRMERNFLRDQSGIRDQMLTLVDLCQFMLPKFAEHLKKCESADLFFCFRMLLVWFKRE 596
M R+ NF D + + L L + P F ++L++ + DLFFC+R LL+ KRE
Sbjct: 104 IMKRLAANFHPDGRAMATKFAHLKLLLRHADPDFYQYLQEAGADDLFFCYRWLLLELKRE 163
Query: 597 FEFSDVCKIWEIFWT 611
F F D ++ E+ W+
Sbjct: 164 FAFDDALRMLEVTWS 178
>At4g28550 [T] KOG2197 Ypt/Rab-specific GTPase-activating protein GYP7 and
related proteins
Length = 408
Score = 93.6 bits (231), Expect = 1e-18
Identities = 76/323 (23%), Positives = 128/323 (39%), Gaps = 106/323 (32%)
Query: 370 IFHGGVENDALRSEVWLFLLGVYPWDSSLQERKELKQAMEEDYNANYKSKWIYRD----- 424
I GG+ + +++ EVW FLLG Y DS+ +ER +L+ NA ++ + +++
Sbjct: 8 IQRGGI-HPSIKGEVWEFLLGAYDPDSTFEERNKLRNHRRYLLNAYWEQYYAWKEECKNM 66
Query: 425 ---------------------VLDDSEEEEYWKDQV---------------------FRI 442
+ + S + + W + + I
Sbjct: 67 VPLVGSGKFVTMAVVAEDGQPLEESSVDNQEWVVKTAITDKRVLQWMLVLSQIGIVNYSI 126
Query: 443 SKDVLRNDRDIPLYRHNTKDGKEDGAKNEEAPNKGDQEEEWEIKNPHLQALKNILISYNI 502
S DV+R DR + Y ++ +Q W+I L Y
Sbjct: 127 SLDVVRTDRYLCFYE-----------------SESNQARLWDI-----------LSIYTW 158
Query: 503 YNPNLGYVQG----------------------------MTDLLSLIYFVLQDEALSFWCF 534
NP++GYVQG M D+ S + +L+DEA +FWCF
Sbjct: 159 LNPDIGYVQGKSTLVLILNLQYRRTCKRIGINHPFCIGMNDICSPMIILLEDEADAFWCF 218
Query: 535 VNFMNRMERNFLRDQS--GIRDQMLTLVDLCQFMLPKFAEHLKKCESADLFFCFRMLLVW 592
M R+ NF + G++ Q+ L + + + P+ +HL+ + + F RML+V
Sbjct: 219 ERAMRRLRENFRTTATSMGVQTQLGMLSQVIKTVDPRLHQHLEDLDGGEYLFAIRMLMVL 278
Query: 593 FKREFEFSDVCKIWEIFWTDYYS 615
F+REF F D +WE+ W Y+
Sbjct: 279 FRREFSFLDALYLWELMWAMEYN 301
>Hs22055332 [T] KOG2197 Ypt/Rab-specific GTPase-activating protein GYP7 and
related proteins
Length = 336
Score = 93.2 bits (230), Expect = 1e-18
Identities = 84/320 (26%), Positives = 144/320 (44%), Gaps = 39/320 (12%)
Query: 336 IAVQRSFPLTKQKWDSLFDSQGRLSITVHEVKDFIFHGGVENDA---LRSEVWLFLLGVY 392
I V+R P+ K +WDS FD G L+ + +DFI +E +R+E W FL G +
Sbjct: 19 ILVKRKPPIDKTEWDSFFDESGHLA----KSRDFICVNILERGLHPFVRTEAWKFLTGYF 74
Query: 393 PWDSSLQERKELKQAMEEDYNANYKSKWIYRDVLDDSEEEEYWKDQVFRISKDVLRNDRD 452
W SS ER + ++Y A Q++ + +L N
Sbjct: 75 SWQSSQDERLTVDSMRRKNYKALC---------------------QMYEKIQPLLEN--- 110
Query: 453 IPLYRHNTKDGKEDGAKNEEAPNKGDQEEEWEIKNPHLQALKNILISYNIYNPNLGYVQG 512
L+R+ T+ + + A++ + D I L+ K +L+SY + N Y QG
Sbjct: 111 --LHRNFTET-RNNIARDIQKIYDKDPLGNVLIDKKRLE--KILLLSY-VCNTQAEYQQG 164
Query: 513 MTDLLSLIYFVLQDEALSFWCFVNFMNRMERNFLRDQSGIRDQMLTLVDLCQFMLPKFAE 572
+++ L +++ + +FW F F+ + E + + + G+ + L L F+ P FAE
Sbjct: 165 FHEMMMLFQLMVEHDHETFWLFQFFLQKTEHSCVIN-IGVAKNLDMLSTLITFLDPVFAE 223
Query: 573 HLKKCESADLFFCFRMLLVWFKREFE-FSDVCKIWEIFWTDYYSSQFQLFFMLAILQKHS 631
HLK + + F F+R F+ F DV ++WE+ T FQ+ ++LQ
Sbjct: 224 HLKGKGAGAVQSLFPWFCFCFQRAFKSFDDVWRLWEVLLTGKPCRNFQVLVAYSMLQMVR 283
Query: 632 DVVVSQLTEFDDVLKYFNDL 651
+ V+ + DD+L N+L
Sbjct: 284 EQVLQESMGGDDILLACNNL 303
>CE00923 [R] KOG1648 Uncharacterized conserved protein contains RUN BRK and
TBC domains
Length = 807
Score = 93.2 bits (230), Expect = 1e-18
Identities = 66/249 (26%), Positives = 117/249 (46%), Gaps = 33/249 (13%)
Query: 435 WKDQVFRISKDVLRNDRDIPLYRHNTKDGKEDGAKNEEAPNKGDQEEEWEIKNPHLQALK 494
++ + RI KDV R DR++ + + KD +L++L+
Sbjct: 588 FRANLHRIDKDVERCDRNLMFF--SNKD--------------------------NLESLR 619
Query: 495 NILISYNIYNPNLGYVQGMTDLLSLIYFVLQDEALSFWCFVNFMNRMERNFLRDQSGIRD 554
++ +Y N GY QGM DLL+ + +DEAL+ CF M R +R + G+
Sbjct: 620 RVMYTYVRRNLEEGYTQGMCDLLAPLLVTFEDEALTLECFSLLMLR-QRGKFPQRPGMSK 678
Query: 555 QMLTLVDLCQFMLPKFAEHLKKCESAD-LFFCFRMLLVWFKREFEFSDVCKIWEIFWTDY 613
+L L L Q + P+ + + A L F FR L+ FKRE + K+WE+ W
Sbjct: 679 CLLNLRSLIQVVDPQIYALISDIDYAQALSFAFRWFLLDFKRELSYECTYKVWEVIWAAQ 738
Query: 614 ---YSSQFQLFFMLAILQKHSDVVVSQLTEFDDVLKYFNDLRNSMDWSDIMIRSELLFIK 670
+ F +FF LA + + DV+++ ++ D++K+FN++ D S ++ +
Sbjct: 739 RLRITDDFAIFFGLATITNYHDVLITNNFDYTDMIKFFNEMAERHDCSRLLSSARTHVKC 798
Query: 671 FQKMIEVLE 679
Q +++ L+
Sbjct: 799 LQNLVQHLK 807
>At2g20440 [T] KOG2197 Ypt/Rab-specific GTPase-activating protein GYP7 and
related proteins
Length = 371
Score = 92.4 bits (228), Expect = 2e-18
Identities = 58/200 (29%), Positives = 90/200 (45%), Gaps = 33/200 (16%)
Query: 420 WIYRDVLDDSEEEEYWKDQVFRISKDVLRNDRDIPLYRHNTKDGKEDGAKNEEAPNKGDQ 479
WI ++ + D E W + +I DV R DR + Y N +Q
Sbjct: 33 WIVKNTVTD-ERVLQWMLSLHQIGLDVARTDRYLCFYE-----------------NDRNQ 74
Query: 480 EEEWEIKNPHLQALKNILISYNIYNPNLGYVQGMTDLLSLIYFVLQDEALSFWCFVNFMN 539
+ W++ L Y N ++GYVQGM D+ S + + DE +FWCF M
Sbjct: 75 SKLWDV-----------LAIYTWLNLDIGYVQGMNDICSPMIILFDDEGDAFWCFERAMR 123
Query: 540 RMERNF--LRDQSGIRDQMLTLVDLCQFMLPKFAEHL--KKCESADLFFCFRMLLVWFKR 595
R+ NF G++ Q+ L + + + P+ +HL K + + F RML+V F+R
Sbjct: 124 RLRENFRATATSMGVQTQLGVLSQVIKTVDPRLHQHLGKKDLDGGEYLFAIRMLMVLFRR 183
Query: 596 EFEFSDVCKIWEIFWTDYYS 615
EF F D +WE+ W Y+
Sbjct: 184 EFSFLDALYLWELMWAMEYN 203
>At4g27100 [T] KOG2197 Ypt/Rab-specific GTPase-activating protein GYP7 and
related proteins
Length = 487
Score = 89.4 bits (220), Expect = 2e-17
Identities = 86/347 (24%), Positives = 142/347 (40%), Gaps = 84/347 (24%)
Query: 344 LTKQKWDSLFDSQGRLSI--TVHEVKDFIFHGGVENDALRSEVWLFLLGVYPWDSSLQER 401
L+ +KW ++F +G L I T+ ++ GG+ + ++R EVW FLLG Y S+ +ER
Sbjct: 35 LSVRKWQAVFVQEGSLHIGKTLRRIR----RGGI-HPSIRGEVWEFLLGCYDPMSTFEER 89
Query: 402 KELKQAMEEDYNANYKS------------KWIYRDVLDDSEEEEYWKDQVFRISKDVLRN 449
++++Q Y A++K ++ V+ ++ + Y D + ++ N
Sbjct: 90 EQIRQRRRLQY-ASWKEECKQMFPVIGSGRFTTAPVITENGQPNY--DPLVLQEINLGTN 146
Query: 450 DRDIPLYRHNTKDGKEDGAKNEEA---------PNKGDQEEEWEIKNPHLQALKNILISY 500
++ T G D + N+ D+ + K +L L +IL Y
Sbjct: 147 SNGSVFFKELTSRGPLDKKIIQWLLTLHQIGLDVNRTDRALVFYEKKENLSKLWDILSVY 206
Query: 501 NIYNPNLGYVQGMTDLLSLIYFVLQDEALSFWCFVNFMNRM------------------- 541
+ ++GY QGM+DL S + +L+DEA +FWCF M R+
Sbjct: 207 AWIDNDVGYCQGMSDLCSPMIILLEDEADAFWCFERLMRRLVLTLHIFSMYLCFWYGLFT 266
Query: 542 ------------------ERNFLRDQS---GIRDQMLTLVDLCQFMLPKFAEHL------ 574
+R R G+ Q+ L + Q + PK +HL
Sbjct: 267 SVSLQSGCIKHVLFFRIEKRGNFRSTGRSVGVEAQLTHLSSITQVVDPKLHQHLGTTRLI 326
Query: 575 -------KKCESADLFFCFRMLLVWFKREFEFSDVCKIWEIFWTDYY 614
K D F RML+V F+REF F D +WE+ W Y
Sbjct: 327 ECWVINADKLGGGDYLFAIRMLMVQFRREFSFCDSLYLWEMMWALEY 373
>At3g59570 [T] KOG2197 Ypt/Rab-specific GTPase-activating protein GYP7 and
related proteins
Length = 549
Score = 87.0 bits (214), Expect = 9e-17
Identities = 44/121 (36%), Positives = 68/121 (55%), Gaps = 1/121 (0%)
Query: 489 HLQALKNILISYNIYNPNLGYVQGMTDLLSLIYFVLQDEALSFWCFVNFMNRMERNF-LR 547
+L + +IL Y +P GY QGM+DL+S F+ +D A +FWCF + R NF +
Sbjct: 411 NLGRMSDILAVYAWVDPATGYCQGMSDLVSPFVFLFEDNADAFWCFEMLIRRTRANFQME 470
Query: 548 DQSGIRDQMLTLVDLCQFMLPKFAEHLKKCESADLFFCFRMLLVWFKREFEFSDVCKIWE 607
+G+ DQ+ +L + Q + HL + + L F FRMLLV F+RE F+ ++WE
Sbjct: 471 GPTGVMDQLQSLWRILQLTDKEMFSHLSRIGAESLHFAFRMLLVLFRRELSFNKALRMWE 530
Query: 608 I 608
+
Sbjct: 531 V 531
Score = 58.2 bits (139), Expect = 5e-08
Identities = 44/172 (25%), Positives = 77/172 (44%), Gaps = 14/172 (8%)
Query: 329 ISPEELNIAVQRSFPLTKQKWDSLFDSQGRLSITVHEVKDFIFHGGVENDALRSEVWLFL 388
+S + + + L +KW +LFD G++S + H+ I GG++ ++R+EVW FL
Sbjct: 61 LSQSRIQVVLTIGKMLKPEKWQALFDGDGKVS-SFHKALKLIILGGID-PSIRAEVWEFL 118
Query: 389 LGVYPWDSSLQERKELKQAMEEDYNANYKSKWIYRDVLD--------DSEEEEYWKDQVF 440
LG Y S+ + R +L+ A E YN K + + S+ + K
Sbjct: 119 LGCYALSSTSEYRTQLRVARRERYNELLKQCQMMHSTVGTGSLAYVVGSKVMDMRKSYKN 178
Query: 441 RISKDVLRNDRDIPLYRHNTKDGKEDGAKN--EEAP--NKGDQEEEWEIKNP 488
+ K+ + R+ L H D D + N E++P G E ++ +P
Sbjct: 179 EVVKEDIDESREACLDGHENTDNHGDWSNNDTEKSPVRRSGSSSESVDLVSP 230
>At2g43490_1 [T] KOG2197 Ypt/Rab-specific GTPase-activating protein GYP7 and
related proteins
Length = 500
Score = 84.3 bits (207), Expect = 6e-16
Identities = 56/185 (30%), Positives = 84/185 (45%), Gaps = 31/185 (16%)
Query: 424 DVLDDSEEEEYWKDQVFRISKDVLRNDRDIPLYRHNTKDGKEDGAKNEEAPNKGDQEEEW 483
+V +D E W + RI DV+R D + Y E+ N G
Sbjct: 346 NVTEDRVSEWLWT--LHRIVVDVVRTDSHLEFY--------------EDPGNLG------ 383
Query: 484 EIKNPHLQALKNILISYNIYNPNLGYVQGMTDLLSLIYFVLQDEALSFWCFVNFMNRMER 543
+ +IL Y +P GY QGM+DL+S + +D A +FWCF + R
Sbjct: 384 --------RMSDILAVYAWVDPATGYCQGMSDLVSPFVVLFEDNADAFWCFEMLIRRTRA 435
Query: 544 NF-LRDQSGIRDQMLTLVDLCQFMLPKFAEHLKKCESADLFFCFRMLLVWFKREFEFSDV 602
NF + +G+ DQ+ +L + Q HL + + L F FRMLLV F+RE F++
Sbjct: 436 NFQMEGPTGVMDQLQSLWHILQITDKDIFSHLSRIGAESLHFAFRMLLVLFRRELSFNEA 495
Query: 603 CKIWE 607
++WE
Sbjct: 496 LRMWE 500
Score = 51.6 bits (122), Expect = 4e-06
Identities = 29/85 (34%), Positives = 47/85 (55%), Gaps = 2/85 (2%)
Query: 329 ISPEELNIAVQRSFPLTKQKWDSLFDSQGRLSITVHEVKDFIFHGGVENDALRSEVWLFL 388
+S + + + L +KW + FDS GR+S +K I GG++ ++R+EVW FL
Sbjct: 35 LSQSRIQVVITIGKMLKPEKWQASFDSDGRVSGFQKALK-LIILGGID-PSIRAEVWEFL 92
Query: 389 LGVYPWDSSLQERKELKQAMEEDYN 413
LG Y S+ + R +L+ A + YN
Sbjct: 93 LGCYALSSTSEYRNQLRVARRKRYN 117
>7303082 [T] KOG2197 Ypt/Rab-specific GTPase-activating protein GYP7 and
related proteins
Length = 1022
Score = 73.2 bits (178), Expect = 1e-12
Identities = 68/249 (27%), Positives = 107/249 (42%), Gaps = 47/249 (18%)
Query: 338 VQRSFPLTKQKWDSL------FDSQGRLSITV-------HEVKDFIFHGGVENDALRSEV 384
VQ++F L+++ +L DS+ RL + E+ IF GG++ +LR V
Sbjct: 175 VQKAFNLSEEHMANLPPRPPMCDSEFRLFLDALGQIQRKDELHRVIFLGGID-PSLRRVV 233
Query: 385 WLFLLGVYPWDSSL-----QERKELKQAMEEDYNANYKSKWIYRDVLDDSEEEEYWKDQV 439
W LL VYP ++ +R E + E Y + W E + +
Sbjct: 234 WKHLLNVYPGGANGLALDGHQRMEFMRRKSEQY-CRLRDTWKAAVKRGSVAGELAYVTSM 292
Query: 440 FRISKDVLRNDRDIPLYRHNTKDGKEDGAKNEEAPNKGDQEEEWEIKNPHLQALKNILIS 499
+ KDVLR DR P Y G +D N ++ AL NIL +
Sbjct: 293 --VKKDVLRTDRLHPFYA-----GSDD--------------------NQNIAALFNILTT 325
Query: 500 YNIYNPNLGYVQGMTDLLSLIYFVLQDEALSFWCFVNFMNRMERNFLRDQSGIRDQMLTL 559
Y + +P++ Y QGM+D+ S + + DEA ++ CF M+RM NF+ D + + L
Sbjct: 326 YALNHPSVSYCQGMSDIASPLLVTMNDEAQAYICFCAIMSRMRGNFMLDGIAMTQKFAHL 385
Query: 560 VDLCQFMLP 568
+ F P
Sbjct: 386 TEALSFYDP 394
>Hs21361637 [R] KOG4567 GTPase-activating protein
Length = 400
Score = 68.9 bits (167), Expect = 3e-11
Identities = 83/355 (23%), Positives = 132/355 (36%), Gaps = 76/355 (21%)
Query: 360 SITVHEVKDFIFHGGVENDALRSEVWLFLLGVYP-----WDSSLQERKEL-----KQAME 409
SI + ++++ F G LR W LL P W S L +++EL ++ +
Sbjct: 20 SIALEKLRELSFSGIPCEGGLRCLCWKILLNYLPLERASWTSILAKQRELYAQFLREMII 79
Query: 410 EDYNANYKSKWIYRDVL---------DDSEEEEYWKDQ--VFRISKDVLRNDRDIPLYRH 458
+ A DV DS Y+KD + +I KDV R DI ++
Sbjct: 80 QPGIAKANMGVSREDVTFEDHPLNPNPDSRWNTYFKDNEVLLQIDKDVRRLCPDISFFQR 139
Query: 459 ------------------------------NTKDGKEDGAKNEEAPNKGDQEE---EWEI 485
T G N +P+K E+E+
Sbjct: 140 ATDYPCLLILDPQNEFETLRKRVEQTTLKSQTVARNRSGVTNMSSPHKNSAPSSLNEYEV 199
Query: 486 K----NPHLQALKNILISYNIYNPNLGYVQGMTDLLSLIYFVL----------QDEALSF 531
H + ++ IL Y NP + YVQGM +++ +Y+ EA +F
Sbjct: 200 LPNGCEAHWEVVERILFIYAKLNPGIAYVQGMNEIVGPLYYTFATDPNSEWKEHAEADTF 259
Query: 532 WCFVNFMNRMERNFLR----DQSGIRDQMLTLVDLCQFMLPKFAEHLKKCESADLFFCFR 587
+CF N M + NF++ Q GI +M + + + L++ FF FR
Sbjct: 260 FCFTNLMAEIRDNFIKSLDDSQCGITYKMEKVYSTLKDKDVELYLKLQEQNIKPQFFAFR 319
Query: 588 MLLVWFKREFEFSDVCKIWEIFWTDYYSSQFQLFFMLAILQKHSDVVVSQLTEFD 642
L + +EF DV +IW+ + D F L A+L ++ QL E D
Sbjct: 320 WLTLLLSQEFLLPDVIRIWDSLFADDNRFDFLLLVCCAMLM----LIREQLLEGD 370
>SPBC530.01 [U] KOG1092 Ypt/Rab-specific GTPase-activating protein GYP1
Length = 514
Score = 66.2 bits (160), Expect = 2e-10
Identities = 77/305 (25%), Positives = 125/305 (40%), Gaps = 66/305 (21%)
Query: 381 RSEVWLFLLGVYPWDSSLQERKELKQAMEEDYNANYKSKWIYRDVLDDSEEEEYWKDQVF 440
R VW +LLG P ++S +E LK+ +E YNA K + ++ W+ V
Sbjct: 222 RPIVWKYLLGYLPCNASRRE-VTLKRKRDE-YNAA-KDSCFNTNTEPPPLDQTIWRQIVL 278
Query: 441 RISKDVLRNDRDIPLYRHNTKDGKEDGAKNEEAPNKGDQEEEWEIKNPHLQA-LKNILIS 499
DV R + I LY+ NP Q L+ IL
Sbjct: 279 ----DVPRTNPSILLYQ-----------------------------NPLTQRMLERILYV 305
Query: 500 YNIYNPNLGYVQGMTDLLS-LIYFVLQD-----------------------EALSFWCFV 535
+ +P GYVQG++DL++ I L + EA ++WC
Sbjct: 306 WASRHPASGYVQGISDLVTPFIQVFLSEYIGDKDPMTYDIALLDETNRNDIEADAYWCLS 365
Query: 536 NFMNRMERNFLRDQSGIRDQMLTLVDLCQFMLPKFAEHLKKCESADLFFCFRMLLVWFKR 595
++ ++ N++ Q GIR Q+ L +L + +HL+ L F FR + R
Sbjct: 366 KLLDGIQDNYIHAQPGIRRQVNNLRELTLRIDEPLVKHLQMEGVDFLQFSFRWMNCLLMR 425
Query: 596 EFEFSDVCKIWEIFWTDYYS--SQFQLFFMLAILQKHSDVVVSQLTEFDDVLKYFNDLRN 653
E S++ ++W+ + + S+F L+ A L K S + Q EF D+L + +
Sbjct: 426 ELSISNIIRMWDTYMAEGVQGFSEFHLYVCAAFLVKWSSEL--QKMEFQDILIFLQSI-P 482
Query: 654 SMDWS 658
+ DWS
Sbjct: 483 TKDWS 487
>7295061 [R] KOG4567 GTPase-activating protein
Length = 403
Score = 64.7 bits (156), Expect = 5e-10
Identities = 48/167 (28%), Positives = 75/167 (44%), Gaps = 26/167 (15%)
Query: 460 TKDGKEDGAKNEEAPNKGDQEEEWEIKNPHLQALKNILISYNIYNPNLGYVQGMTDLLSL 519
TK E+ A EE QE WE+ ++ IL Y NP GYVQGM +++
Sbjct: 196 TKRSVENYAAMEEG-----QEAHWEV-------VQRILFIYAKLNPGQGYVQGMNEIVGP 243
Query: 520 IYFVLQD----------EALSFWCFVNFMNRMERNFLRD----QSGIRDQMLTLVDLCQF 565
IY+V+ EA F+CF M+ + F++ + GI+ M L ++ +
Sbjct: 244 IYYVMASDPDLTYRAHAEADCFFCFTALMSEIRDFFIKTLDDAEGGIKFMMARLSNMLKS 303
Query: 566 MLPKFAEHLKKCESADLFFCFRMLLVWFKREFEFSDVCKIWEIFWTD 612
E L+ E ++ FR L + +EF DV +IW+ + D
Sbjct: 304 KDLSIYELLRSQELHPQYYSFRWLTLLLSQEFPLPDVLRIWDSVFAD 350
>At1g04830 [R] KOG4567 GTPase-activating protein
Length = 451
Score = 62.0 bits (149), Expect = 3e-09
Identities = 70/309 (22%), Positives = 126/309 (40%), Gaps = 81/309 (26%)
Query: 361 ITVHEVKDFIFHGGVENDALRSEVWLFLLGVYPWDSSL------QERKELKQAMEE---- 410
I + E++ ++ +RS VW LLG P + SL Q+R + K +E
Sbjct: 108 INMKELRSLALQSLPDSPGIRSTVWKLLLGYLPPERSLWSTELKQKRSQYKHYKDELLTS 167
Query: 411 ------------------DYNANYKSK-WIYRDVLDDSEE----------EEYWKDQ--V 439
+Y+ +S+ + R + D + Y++D +
Sbjct: 168 PVSDPEITWKMVRSKGFDNYDLKSESRCMLARSRITDEDHPLSLGKASIWNTYFQDTETI 227
Query: 440 FRISKDVLRNDRDIPLYRHNTKDGKEDGAKNEEAPNKGDQEEEWEIKNPHLQALKNILIS 499
+I +DV R DIP + G+ A++ + +++KNIL+
Sbjct: 228 EQIDRDVKRTHPDIPFF-----SGESSFARSNQ------------------ESMKNILLV 264
Query: 500 YNIYNPNLGYVQGMTDLLSLIYFVLQD----------EALSFWCFVNFMNRMERNFLRDQ 549
+ N + YVQGM ++L+ I++V ++ EA +F+CFV ++ R+F Q
Sbjct: 265 FAKLNQGIRYVQGMNEILAPIFYVFRNDPDEDSSSHAEADAFFCFVELLSGF-RDFYCQQ 323
Query: 550 -----SGIRDQMLTLVDLCQFMLPKFAEHLKKCESAD-LFFCFRMLLVWFKREFEFSDVC 603
GIR + L L + + HL+ + F+ FR + + +EF F D
Sbjct: 324 LDNSVVGIRSAITRLSQLVRKHDEELWRHLEITTKVNPQFYAFRWITLLLTQEFSFFDSL 383
Query: 604 KIWEIFWTD 612
IW+ +D
Sbjct: 384 HIWDALLSD 392
>7300700 [U] KOG1092 Ypt/Rab-specific GTPase-activating protein GYP1
Length = 545
Score = 60.1 bits (144), Expect = 1e-08
Identities = 53/211 (25%), Positives = 90/211 (42%), Gaps = 33/211 (15%)
Query: 491 QALKNILISYNIYNPNLGYVQGMTDLLSLIYFVLQDEAL--------------------- 529
+ + IL + I +P GYVQG+ DL++ + V EAL
Sbjct: 325 EMFERILFIWAIRHPASGYVQGINDLVTPFFIVFLQEALTPNTDLEKYDMSTLPEETRNI 384
Query: 530 ----SFWCFVNFMNRMERNFLRDQSGIRDQMLTLVDLCQFMLPKFAEHLKKCESADLFFC 585
SFWC F++ ++ N++ Q GI++++ L DL Q + HL+ L F
Sbjct: 385 IEADSFWCLSKFLDCIQDNYIFAQLGIQEKVNQLKDLIQRIDVNLHRHLQAHGVDYLQFS 444
Query: 586 FRMLLVWFKREFEFSDVCKIWEIFWTDYYSSQFQLF--FMLAILQKHSDVVVSQLTEFDD 643
FR + RE ++W+ + + S F LF ++ A H + Q +F
Sbjct: 445 FRWMNNLLTRELPLHCTIRLWDTYLAE--SDGFALFHLYVCAAFLLHWKEQLMQQNDFQG 502
Query: 644 VLKYFNDLRNSMDWSDIMIR---SELLFIKF 671
++ +L + +WSD I +E +KF
Sbjct: 503 LMLLLQNL-PTHNWSDRQINVLLAEAFRLKF 532
>CE28759 [TR] KOG2223 Uncharacterized conserved protein contains TBC domain
Length = 614
Score = 58.5 bits (140), Expect = 4e-08
Identities = 36/178 (20%), Positives = 82/178 (45%), Gaps = 13/178 (7%)
Query: 488 PHLQALKNILISYNIYNPNLGYVQGMTDLLSLIYFVLQDEALSFWCFVNFMNRMERNFLR 547
P+ L +L +Y I P++GYVQ MT + +++ + + F++F N ++R+
Sbjct: 375 PYYDHLLKLLSAYAILRPDIGYVQSMTFIAAVLLIQMDP----YPAFISFANLLDRSLQS 430
Query: 548 DQSGIRDQMLTLVDLC-----QFMLPKFAEHLKKCESADLFFCFRMLLVWFKREFEFSDV 602
G++ +T + + LP +HL K + + + +
Sbjct: 431 AFFGLKQPQMTEYFIAYDRYLEQELPALHQHLDKLDVRPDLYLIEWTFAMYAKSLPLDVT 490
Query: 603 CKIWEIFWTDYYSSQFQLFFMLAILQKHSDVVVSQLTEFDDVLKYFNDLRNSMDWSDI 660
C+IW++++ D +F L IL+ + +++ +FDD +++ L N++ +++
Sbjct: 491 CRIWDVYFRD--GEEFLFKAALGILRMYEPKLLTM--DFDDCVEFLTKLPNTLTGAEL 544
>At4g13730 [R] KOG4567 GTPase-activating protein
Length = 449
Score = 58.2 bits (139), Expect = 5e-08
Identities = 54/218 (24%), Positives = 96/218 (43%), Gaps = 45/218 (20%)
Query: 410 EDYNANYKSKWIYRDVLDDSEEEEYWKDQVFRISKDVLRNDRDIPLYRHNTKDGKEDGAK 469
ED+ + + ++ + D+E E +I +DV+R D+ +
Sbjct: 206 EDHPLSLGTTSLWNNFFKDTEVLE-------QIERDVMRTHPDMHFF------------S 246
Query: 470 NEEAPNKGDQEEEWEIKNPHLQALKNILISYNIYNPNLGYVQGMTDLLSLIYFVLQD--- 526
+ A K +Q+ ALKNIL + NP + YVQGM ++L+ I+++ ++
Sbjct: 247 GDSAVAKSNQD-----------ALKNILTIFAKLNPGIRYVQGMNEILAPIFYIFKNDPD 295
Query: 527 -------EALSFWCFVNFMNRMERNFLR--DQS--GIRDQMLTLVDLCQFMLPKFAEHLK 575
E+ +F+CFV M+ NF + D S GIR + L L + + HL+
Sbjct: 296 KGNAAYAESDAFFCFVELMSGFRDNFCQQLDNSVVGIRYTITRLSLLLKHHDEELWRHLE 355
Query: 576 KCESAD-LFFCFRMLLVWFKREFEFSDVCKIWEIFWTD 612
+ F+ FR + + +EF F + IW+ +D
Sbjct: 356 VTTKINPQFYAFRWITLLLTQEFNFVESLHIWDTLLSD 393
>At3g02460 [R] KOG1102 Rab6 GTPase activator GAPCenA and related TBC domain
proteins
Length = 304
Score = 58.2 bits (139), Expect = 5e-08
Identities = 39/157 (24%), Positives = 77/157 (48%), Gaps = 8/157 (5%)
Query: 488 PHLQALKNILISYNIYNPNLGYVQGMTDLLSLIYFVLQDEALSFWCFVNFMN-----RME 542
P ++L N+L +Y++Y+ ++GYVQGM + L+ + +E +FW V + ME
Sbjct: 150 PGQRSLYNVLKAYSVYDRDVGYVQGMGFIAGLLLLYMSEED-AFWLLVALLKGAVHAPME 208
Query: 543 RNFLRDQSGIRDQMLTLVDLCQFMLPKFAEHLKKCESADLFFCFRMLLVWFKREFEFSDV 602
+ ++ + L L + ++PK EH + + + + F F F
Sbjct: 209 GLYHAGLPLVQQYLFQLESLVKELIPKLGEHFTQEMINPSMYASQWFITVFSYSFPFPLA 268
Query: 603 CKIWEIFWTDYYSSQFQLFFMLAILQKHSDVVVSQLT 639
+IW++F ++ F++ LA+L+ D +VS++T
Sbjct: 269 LRIWDVFLSEGVKIVFKV--GLALLKYCQDELVSKVT 303
>Hs14733591 [TR] KOG2223 Uncharacterized conserved protein contains TBC domain
Length = 693
Score = 57.0 bits (136), Expect = 1e-07
Identities = 42/152 (27%), Positives = 69/152 (44%), Gaps = 11/152 (7%)
Query: 488 PHLQALKNILISYNIYNPNLGYVQGMTDLLSLIYFVLQDEALSFWCFVNFMNR-MERNFL 546
P+ L +IL +Y Y P++GYVQGM+ + +++ L D A +F F N +N+ + F
Sbjct: 485 PYHDMLHSILGAYTCYRPDVGYVQGMSFIAAVLILNL-DTADAFIAFSNLLNKPCQMAFF 543
Query: 547 RDQSGIRDQMLTLVDLCQFM----LPKFAEHLKKCESADLFFCFRMLLVWFKREFEFSDV 602
R G+ MLT + LPK H KK + + + +
Sbjct: 544 RVDHGL---MLTYFAAFEVFFEENLPKLFAHFKKNNLTPDIYLIDWIFTLYSKSLPLDLA 600
Query: 603 CKIWEIFWTDYYSSQFQLFFMLAILQKHSDVV 634
C+IW++F D +F L IL+ D++
Sbjct: 601 CRIWDVFCRD--GEEFLFRTALGILKLFEDIL 630
>ECU03g0560 [R] KOG4567 GTPase-activating protein
Length = 336
Score = 57.0 bits (136), Expect = 1e-07
Identities = 68/296 (22%), Positives = 128/296 (42%), Gaps = 36/296 (12%)
Query: 361 ITVHEVKDFIFHGGVENDALRSEVWLFLLGVYPWDSSLQERKELKQAMEEDYNANYKSKW 420
+ V EVK + ++G N +LR + W LG Y S + R E+ + N +S +
Sbjct: 28 LDVREVKKYCYYG-FSNASLRPKYWKVFLGYY---SKNKFRTEM-------FLRNMRSSY 76
Query: 421 IYRDVLDDSEEEEYWKDQVFRISKDVLRNDRDIPLYRHNTKDGKEDGAKNEEAPNKGDQE 480
+ + +E KD ++ V+ ND + T + K+ G K
Sbjct: 77 SF--YIGKIGDEFEGKDGCYK----VIENDVCRTFIKPRT-ECKDSGEKRRYCEFLDSIH 129
Query: 481 EEWEIKNPHLQALKNILISYNIYNPNLGYVQGMTDLLSLIYFVL---QD-------EALS 530
+ + H ++ IL Y + N ++ YVQGM +L+ IY+VL +D E S
Sbjct: 130 RDTQ--ETHRAVIERILKCYAMTNSSVKYVQGMNLVLTAIYYVLYLSEDEEDRRYCEEDS 187
Query: 531 FWCFVNFMNRMERNFLRD----QSGIRDQMLTLVDLCQFMLPKFAEHLKKCESADLFFCF 586
F+CF + M + NF+ D GI +M ++++ + + +K+ + F
Sbjct: 188 FFCFNSLMVEIGDNFMEDLDQCSGGIVHRMSRVMEIVEEADRELYRAMKRKGLVEGGFHM 247
Query: 587 RMLLVWFKREFEFSDVCKIWEIFWTDYYSSQFQLFFMLAILQKHSDVVVSQLTEFD 642
+ +L+ F F+ DV +W+ +D + L+ + + V++ + +FD
Sbjct: 248 KWILLMFVSCFDIEDVVWLWDRLLSDSCRFEMVLYCCASAIIMARSVIIRE--DFD 301
>At5g15930 [R] KOG1102 Rab6 GTPase activator GAPCenA and related TBC domain
proteins
Length = 356
Score = 55.8 bits (133), Expect = 2e-07
Identities = 47/211 (22%), Positives = 99/211 (46%), Gaps = 13/211 (6%)
Query: 488 PHLQALKNILISYNIYNPNLGYVQGMTDLLSLIYFVLQDEALSFWCFVNFMNRMERNFLR 547
P ++L N+L +Y++Y+ ++GYVQGM + L+ + +E +FW V + + +
Sbjct: 147 PGQRSLYNVLKAYSVYDRDVGYVQGMGFIAGLLLLYMSEED-AFWLLVALLKGAVHSPIE 205
Query: 548 D--QSG---IRDQMLTLVDLCQFMLPKFAEHLKKCESADLFFCFRMLLVWFKREFEFSDV 602
Q+G ++ +L L + ++PK EH + + + + F F
Sbjct: 206 GLYQAGLPLVQQYLLQFDQLVRELMPKLGEHFTQEMINPSMYASQWFITVFSYSLPFHSA 265
Query: 603 CKIWEIFWTDYYSSQFQLFFMLAILQK-HSDVVVSQLTEFDDVLKYFNDLRNSMDWSDIM 661
+IW++F + F++ LA+L+ H D++ E L+ F + ++MD ++
Sbjct: 266 LRIWDVFLAEGVKIVFKV--GLALLKHCHDDLLKLPFEELMHALRNFPE--DAMDPDTLL 321
Query: 662 IRSELLFIKFQKMIEVLEREEELISKRTTST 692
+ IK K +E ++++ + + T T
Sbjct: 322 PLA--YSIKVSKRLEEMKQDCDKAVAKPTQT 350
>Hs22056446 [U] KOG2058 Ypt/Rab GTPase activating protein
Length = 788
Score = 55.5 bits (132), Expect = 3e-07
Identities = 40/160 (25%), Positives = 73/160 (45%), Gaps = 6/160 (3%)
Query: 490 LQALKNILISYNIYNPNLGYVQGMTDLLSLIYFVLQDEALSFWCFVNFMN-RMERN-FLR 547
+Q L+N+L++++ NP++GY QG+ L+++ L+ E +FWC V + M R+ + +
Sbjct: 606 IQKLRNVLLAFSWRNPDIGYCQGLNRLVAVALLYLEQED-AFWCLVTIVEVFMPRDYYTK 664
Query: 548 DQSGIRDQMLTLVDLCQFMLPKFAEHLKKCESADLFFCFRMLLVWFKREFEFSDVCKIWE 607
G + DL LP+ H ++ + F LV F + KIW+
Sbjct: 665 TLLGSQVDQRVFRDLMSEKLPRLHGHFEQYKVDYTLITFNWFLVVFVDSVVSDILFKIWD 724
Query: 608 IFWTDYYSSQFQLFFMLAILQKHSDVVVSQLTEFDDVLKY 647
F Y +F L K+ + + +L + + KY
Sbjct: 725 SF---LYEGPKVIFRFALALFKYKEEEILKLQDSMSIFKY 761
>Hs14745035 [TR] KOG2223 Uncharacterized conserved protein contains TBC domain
Length = 775
Score = 54.7 bits (130), Expect = 5e-07
Identities = 38/150 (25%), Positives = 69/150 (45%), Gaps = 5/150 (3%)
Query: 488 PHLQALKNILISYNIYNPNLGYVQGMTDLLSLIYFVLQDEALSFWCFVNFMNR-MERNFL 546
P+ L +IL +Y Y P++GYVQGM+ + +++ L +EA +F F N +N+ + F
Sbjct: 566 PYHDVLHSILGAYTCYRPDVGYVQGMSFIAAVLILNL-EEADAFIAFANLLNKPCQLAFF 624
Query: 547 R-DQSGIRDQMLTLVDLCQFMLPKFAEHLKKCESADLFFCFRMLLVWFKREFEFSDVCKI 605
R D S + T + L K H K + + + + C++
Sbjct: 625 RVDHSMMLKYFATFEVFFEENLSKLFLHFKSYSLTPDIYLIDWIFTLYSKSLPLDLACRV 684
Query: 606 WEIFWTDYYSSQFQLFFMLAILQKHSDVVV 635
W++F D +F L IL+ + D+++
Sbjct: 685 WDVFCRD--GEEFLFRTGLGILRLYEDILL 712
>7296688 [R] KOG4436 Predicted GTPase activator NB4S/EVI5 (contains TBC
domain)/Calmodulin-binding protein Pollux (contains PTB
and TBC domains)
Length = 1379
Score = 53.9 bits (128), Expect = 9e-07
Identities = 46/207 (22%), Positives = 99/207 (47%), Gaps = 7/207 (3%)
Query: 492 ALKNILISYNIYNPNLGYVQGMTDLLSLIYFVLQDEALSFWCFVNFMNR--MERNFLRDQ 549
+L N+L +Y+I +P LGY QG+ + ++ + DEA SF + M R M +L D
Sbjct: 817 SLFNLLKAYSILDPELGYCQGLGFICGVL-LLHCDEANSFQLLKHLMFRRNMRTKYLPDM 875
Query: 550 SGIRDQMLTLVDLCQFMLPKFAEHLKKCESADLFFCFRMLLVWFKREFEFSDVCKIWEIF 609
+ Q+ L L + LP L + + + + +L F +F V +++++
Sbjct: 876 KKFQLQLYQLSRLVKDHLPDLYVWLDQNDVSPTLYAAPWILTVFSSQFPLGFVARVFDLL 935
Query: 610 WTDYYSSQFQLFFMLAILQKHSDVVVSQLTEFDDVLKYFNDLRNSMDWSDIMIRSELLF- 668
+ + SS F +A+L H ++++ F++++ Y + M+ + + +L+F
Sbjct: 936 FLE--SSDVIFKFAIALLSVHKQQLLAK-DNFEEIMDYLKTVVPKMEHTCMEQIMKLVFS 992
Query: 669 IKFQKMIEVLEREEELISKRTTSTGYN 695
+ K + + E ++ + T+T ++
Sbjct: 993 MDIGKQLAEYKVEYNVLQEEITTTNHH 1019
>Hs8922167 [U] KOG2058 Ypt/Rab GTPase activating protein
Length = 468
Score = 52.8 bits (125), Expect = 2e-06
Identities = 36/157 (22%), Positives = 72/157 (44%), Gaps = 5/157 (3%)
Query: 493 LKNILISYNIYNPNLGYVQGMTDLLSLIYFVLQDEALSFWCFVNFMNRM--ERNFLRDQS 550
L+ +L++++ NP +GY QG+ L ++ VL++E +FWC V + + + +
Sbjct: 235 LRRVLLAFSWQNPTIGYCQGLNRLAAIALLVLEEEESAFWCLVAIVETIMPADYYCNTLT 294
Query: 551 GIRDQMLTLVDLCQFMLPKFAEHLKKCESADLFFCFRMLLVWFKREFEFSDVCKIWEIFW 610
+ L DL LP+ HL + F LV F + + ++W+ F
Sbjct: 295 ASQVDQRVLQDLLSEKLPRLMAHLGQHHVDLSLVTFNWFLVVFADSLISNILLRVWDAFL 354
Query: 611 TDYYSSQFQLFFMLAILQKHSDVVVSQLTEFDDVLKY 647
Y ++ + LAI K+++ + +L ++ +Y
Sbjct: 355 --YEGTKVVFRYALAIF-KYNEKEILRLQNGLEIYQY 388
>SPAC1952.17c [R] KOG4567 GTPase-activating protein
Length = 541
Score = 52.4 bits (124), Expect = 3e-06
Identities = 37/145 (25%), Positives = 61/145 (41%), Gaps = 27/145 (18%)
Query: 489 HLQALKNILISYNIYNPNLGYVQGMTDLLSLIYFVLQD----------EALSFWCFVNFM 538
H +A + IL Y NP +GYVQGM ++L+ +Y+VL E +F+ F M
Sbjct: 170 HREAAERILFIYAKLNPGIGYVQGMNEILAPLYYVLATDPTYENYYLCECDAFFLFTQMM 229
Query: 539 NRMERNFLRDQSGIRDQMLTLVDLCQFMLPKFAEHLKKCESA-----------DLFFCFR 587
++ + + D + F++ KF E LKK + ++ FR
Sbjct: 230 VQVRDLYEKTLDHDSDHGI------HFLMSKFTERLKKYDYELWENLEEKQIHPTYYSFR 283
Query: 588 MLLVWFKREFEFSDVCKIWEIFWTD 612
+EF DV ++W+ D
Sbjct: 284 WFTCLLSQEFPLPDVIRLWDSIIAD 308
>At2g30710 [U] KOG1092 Ypt/Rab-specific GTPase-activating protein GYP1
Length = 343
Score = 52.4 bits (124), Expect = 3e-06
Identities = 65/304 (21%), Positives = 129/304 (42%), Gaps = 61/304 (20%)
Query: 380 LRSEVWLFLLGVYPWDSSLQERKELKQAMEEDYNANYKSKWIYRDVLDDSEEEEYWKDQV 439
+R +VW LLG P +S +E ++ +E +S + D L DSE + + +
Sbjct: 51 MRPDVWRLLLGYAPPNSDRREAVLRRKRLEY-----LESVGQFYD-LPDSERSDDEINML 104
Query: 440 FRISKDVLRNDRDIPLYRHNTKDGKEDGAKNEEAPNKGDQEEEWEIKNPHLQALKNILIS 499
+I+ D R D+ + Q+E+ + ++L+ IL +
Sbjct: 105 RQIAVDCPRTVPDVSFF----------------------QQEQVQ------KSLERILYT 136
Query: 500 YNIYNPNLGYVQGMTDLLS--LIYF---------------------VLQDEALSFWCFVN 536
+ I +P GYVQG+ DL++ L+ F V EA +WC
Sbjct: 137 WAIRHPASGYVQGINDLVTPFLVIFLSEYLDGGVDSWSMDDLSAEKVSDVEADCYWCLTK 196
Query: 537 FMNRMERNFLRDQSGIRDQMLTLVDLCQFMLPKFAEHLKKCESADLFFCFRMLLVWFKRE 596
++ M+ ++ Q GI+ + L +L + + + H+++ L F FR RE
Sbjct: 197 LLDGMQDHYTFAQPGIQRLVFKLKELVRRIDEPVSRHMEEHGLEFLQFAFRWYNCLLIRE 256
Query: 597 FEFSDVCKIWEIFWTDYYS-SQFQLFFMLAILQKHSDVVVSQLTEFDDVLKYFNDLRNSM 655
F+ + ++W+ + + + F ++ + L SD + + +F +++ + L +
Sbjct: 257 IPFNLINRLWDTYLAEGDALPDFLVYIYASFLLTWSDEL--KKLDFQEMVMFLQHL-PTH 313
Query: 656 DWSD 659
+WSD
Sbjct: 314 NWSD 317
>ECU04g1530 [U] KOG1092 Ypt/Rab-specific GTPase-activating protein GYP1
Length = 329
Score = 52.0 bits (123), Expect = 3e-06
Identities = 45/182 (24%), Positives = 84/182 (45%), Gaps = 22/182 (12%)
Query: 505 PNLGYVQGMTDLLSLIYFVL--------QDEALSFWCFVNFMNRMERNFLRDQSGI---R 553
P LGY+QGM D+L I F+L + E+ +++C+ ++ ++ N + QSG+
Sbjct: 147 PLLGYIQGMADIL--IPFILVFLNENAERAESNAYFCYARLLDEIQYNMVELQSGMIEGL 204
Query: 554 DQMLTLVDLCQFMLPKFAEHLKKCESADLFFCFRMLLVWFKREFEFSDVCKIWEIFWTDY 613
D +L VD P F + L++ F FR F REF+ + KI + +
Sbjct: 205 DFVLQTVD------PDFHKFLQEIGLEIHMFAFRWFNCLFVREFKVPILLKILDTIFASD 258
Query: 614 YSSQFQLFFMLAILQKHSDVVVSQLTEFDDVLKYFNDLRNSMDWSDIMIRSELLFIKFQK 673
++ ++F +A+L K +V +F + + + + +W + I L KF +
Sbjct: 259 SINESLVYFGVALLMKFKSTLVE--NDFSHNILFLQSIYD-REWEEAEIELILSSAKFYR 315
Query: 674 MI 675
+
Sbjct: 316 KV 317
>7303241 [R] KOG1102 Rab6 GTPase activator GAPCenA and related TBC domain
proteins
Length = 457
Score = 51.6 bits (122), Expect = 4e-06
Identities = 46/208 (22%), Positives = 89/208 (42%), Gaps = 12/208 (5%)
Query: 457 RHNTKDGKEDGAKNEEAPNKGDQEEEWEIKNPHLQALKNILISYNIYNPNLGYVQGMTDL 516
+++T+ + D N + + E + +K +L N+L +Y+IYN LGY QGM +
Sbjct: 139 KYSTETRQIDADVNRQFRDNLAFRERYSVKQC---SLFNVLNAYSIYNSELGYCQGMACV 195
Query: 517 LSLIYFVLQDEALSFWCFVNFMNRMERNFLRDQSGIRDQMLTLVD----LCQFMLPKFAE 572
++ L +E +FW + + ++ +D + ++ K +
Sbjct: 196 AGVLLLYLHEEE-AFWALNTLITDQKYGMHGLFIEGFPKLTRFIDHHDRIMSKIMRKLHK 254
Query: 573 HLKKCESADLFFCFRMLLVWFKREFEFSDVCKIWEIFWTDYYSSQFQLFFMLAILQKHSD 632
H K L + + V F FS ++W+IF D + L + IL H D
Sbjct: 255 HFTKHNVDALLYAIKWFFVVFVERVPFSLSLRVWDIFMLD--GDRVILSMAITILYLHKD 312
Query: 633 VVVSQLTEFDDVLKYFN-DLRNSMDWSD 659
++ +L + D +++Y L + +SD
Sbjct: 313 ELL-RLKDMDAIIEYLQVRLHKNFGYSD 339
>7300111 [U] KOG2058 Ypt/Rab GTPase activating protein
Length = 299
Score = 50.4 bits (119), Expect = 1e-05
Identities = 58/281 (20%), Positives = 106/281 (37%), Gaps = 41/281 (14%)
Query: 394 WDSSLQERKELKQAMEEDYNANYKSKWIYRDVLDDSEEEEYWKD-----QVFRISKDVLR 448
W++ LQ+ +L Q + K K R + + W R S D+ R
Sbjct: 15 WEAILQQNTDLTQV-------DAKLKRYIRKGIPGPYRPDVWMKISGAAAAQRRSPDLFR 67
Query: 449 NDRDIPLYRHNTKDGKEDGAKNEEAPNKGDQEEEWEIKNPHLQALKNILISYNIYNPNLG 508
N L R D + + + + P +++K Q L NILI+Y +N ++G
Sbjct: 68 N-----LLRTEPFDKEISDSISIDLPRTFPDNIHFDMKK---QRLYNILIAYAHHNRDVG 119
Query: 509 YVQGMTDLLSLIYFVLQDEALSFWCFVNFMNRM--------ERNFLRDQSGIRDQMLTLV 560
Y QG+ + L+ V DE SFW + + + N LRD + R+ ++
Sbjct: 120 YCQGLNYIAGLLLIVTDDEEKSFWLLKHIVENIVPQYHSHNMANLLRDLAVFRELVIR-- 177
Query: 561 DLCQFMLPKFAEHLKKCESADLFFCFRMLLVWFKREFEFSDVCKIWEIFWTDYYSSQFQL 620
+P H+ + + F V +IW+ + + Y F+
Sbjct: 178 -----RIPAVNRHVDNLGLPYPVIASKWFICIFAEVLPVETVLRIWDCVFAEGYKIVFRA 232
Query: 621 FFMLAILQKHSDVVVSQLTEFDDVLKYFNDLRNSMDWSDIM 661
+ + K++ + DD+ N R++M +I+
Sbjct: 233 ALTMFVTHKNA------ILGCDDIAALANLFRDTMIQDNIV 267
Database: KOG eukaryal database 04/03
Posted date: Apr 14, 2003 1:07 PM
Number of letters in database: 30,389,216
Number of sequences in database: 60,738
Lambda K H
0.319 0.136 0.410
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 46,337,802
Number of Sequences: 60738
Number of extensions: 2085674
Number of successful extensions: 6577
Number of sequences better than 1.0e-05: 47
Number of HSP's better than 0.0 without gapping: 22
Number of HSP's successfully gapped in prelim test: 25
Number of HSP's that attempted gapping in prelim test: 6443
Number of HSP's gapped (non-prelim): 76
length of query: 742
length of database: 30,389,216
effective HSP length: 114
effective length of query: 628
effective length of database: 23,465,084
effective search space: 14736072752
effective search space used: 14736072752
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)