ORF STATUS Function Best COG Functional category Pathways and functional systems
r_klactIV4775 good L KOG2028 Replication, recombination and repair ATPase related to the helicase subunit of the Holliday junction resolvase
Only best alignment is shown:
BLASTP 2.2.3 [May-13-2002]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= r_klactIV4775 1631039 1629363 -559
(559 letters)
Database: KOG eukaryal database 04/03
60,738 sequences; 30,389,216 total letters
Searching..................................................done
Color Key for Alignment Scores: 
Score E
Sequences producing significant alignments: (bits) Value
YNL218w [L] KOG2028 ATPase related to the helicase subunit of th... 654 0.0
SPAC26H5.02c [L] KOG2028 ATPase related to the helicase subunit ... 372 e-103
Hs18426902 [L] KOG2028 ATPase related to the helicase subunit of... 358 2e-98
At1g24290 [L] KOG2028 ATPase related to the helicase subunit of ... 324 2e-88
Hs18426904 [L] KOG2028 ATPase related to the helicase subunit of... 306 7e-83
YNL290w [L] KOG0990 Replication factor C subunit RFC5 68 3e-11
YOL094c [L] KOG0991 Replication factor C subunit RFC2 66 1e-10
7292439 [L] KOG0991 Replication factor C subunit RFC2 64 6e-10
ECU02g0290 [L] KOG0990 Replication factor C subunit RFC5 64 8e-10
Hs4506487 [L] KOG0991 Replication factor C subunit RFC2 63 1e-09
Hs6677723 [L] KOG0990 Replication factor C subunit RFC5 62 2e-09
CE17139 [L] KOG0991 Replication factor C subunit RFC2 60 7e-09
At4g24790 [L] KOG0989 Replication factor C subunit RFC4 59 2e-08
At1g63160 [L] KOG0991 Replication factor C subunit RFC2 53 1e-06
YJR068w [L] KOG0989 Replication factor C subunit RFC4 52 2e-06
SPAC1687.03c [L] KOG0991 Replication factor C subunit RFC2 52 3e-06
At1g14460 [L] KOG0989 Replication factor C subunit RFC4 50 9e-06
>YNL218w [L] KOG2028 ATPase related to the helicase subunit of the Holliday
junction resolvase
Length = 587
Score = 654 bits (1687), Expect = 0.0
Identities = 340/574 (59%), Positives = 423/574 (73%), Gaps = 25/574 (4%)
Query: 5 EQTITCPVCGKKVAFLKINSHLDKCTEEPKGNREQP-TLKTFLSSKRK-----ADEIVID 58
EQ I+CP+C +KV F INSHLD C +E +P T+ + L+ +K +++ +
Sbjct: 9 EQLISCPICSRKVFFSLINSHLDICGKEKSKPSSRPQTVSSLLAGPKKRKQANSEKFIDL 68
Query: 59 DVPDNSGVALQSTTSCDCQIQGTDTREHKMR----------KPEWTRPMANNMDLEIKQL 108
+ D+ + S D +I +++ K +P +R +N D E + L
Sbjct: 69 ENKDHEIKPGLKSESDDIEIVENESKRFKAAPSTDFAKSIVEPASSRDQLHN-DYESRWL 127
Query: 109 QKVQHLPLSEKLRPKSLNDYIGQQHILNRETGCLYLYIEKGIIPSMILWGPPGVGKTSLA 168
QK+ HLPLSEKLRPK L DY+GQQHIL+++ G L+ YI++G IPSMILWGPPGVGKTSLA
Sbjct: 128 QKISHLPLSEKLRPKELRDYVGQQHILSQDNGTLFKYIKQGTIPSMILWGPPGVGKTSLA 187
Query: 169 RLLTNTVNIQSDAS---TKYLLLETSATKANTTELRSIFDKSKKEYHLTKRMTVLFIDEI 225
RLLT T S+ S ++Y ++ETSATKANT ELR IF+KSKKEY LTKR TVLFIDEI
Sbjct: 188 RLLTKTATTSSNESNVGSRYFMIETSATKANTQELRGIFEKSKKEYQLTKRRTVLFIDEI 247
Query: 226 HRFNKAQQDLLLPHIENGDIVLIGATTENPSFQLNNALLSRCQLFVLEKLNDKELKIVLI 285
HRFNK QQDLLLPH+ENGDI+LIGATTENPSFQLNNAL+SRC +FVLEKLN EL IVL
Sbjct: 248 HRFNKVQQDLLLPHVENGDIILIGATTENPSFQLNNALISRCLIFVLEKLNVNELCIVLS 307
Query: 286 RAIALLNKYRSLIWKYSAPLKFDEDCFSFIYDTAMGDTRRAINLLELLEISTRFKV--EG 343
R IALLNK R +W PLK ++ D ++GDTRRA+N+LE++E+STR + E
Sbjct: 308 RGIALLNKCRKQVWNIENPLKLSRSILEYVVDLSVGDTRRALNMLEMIEVSTRERKADEE 367
Query: 344 PISLDKVKGLISSNGE--LRTYYDTHGENHYDTISAFHKSVRGGDENAALYYLARMLQGG 401
+S+D V+ +I +N L TYYD G+NHYDTISAFHKS+RGGDENA+LYYLARMLQGG
Sbjct: 368 ELSIDDVRDIIKNNSSNGLNTYYDPKGDNHYDTISAFHKSIRGGDENASLYYLARMLQGG 427
Query: 402 EDPLFIARRMIRIASEDVGLSDPFQLPFSVAAHDAVMKVGLPEAELALAQCAVSLSRASK 461
EDPL++ARRMIRIASED+GL D LP +VAAHDAVMKVGLPEA+LALAQC V+L+RA K
Sbjct: 428 EDPLYVARRMIRIASEDIGLRDSSLLPLAVAAHDAVMKVGLPEADLALAQCCVALARAPK 487
Query: 462 SVELYRGWNKLKAMLKTNESGAADCPIPLHIRNAPTRMMEELGYGKGYKYNPNFKDGKVL 521
SVELYR W KL+AM+ N A IP+HIRNAPT++MEELGY KGYKYNP++ +GKV
Sbjct: 488 SVELYRAWKKLRAMMSENMYSLASSEIPMHIRNAPTKLMEELGYHKGYKYNPDYIEGKVQ 547
Query: 522 QEYFPQELLDRCGRK-ELTFLNGKALGDMEDPDL 554
Q+YFP+E+L++C K +L FL+GK LGD EDPDL
Sbjct: 548 QDYFPKEVLEKCPNKTDLKFLDGKHLGDKEDPDL 581
>SPAC26H5.02c [L] KOG2028 ATPase related to the helicase subunit of the Holliday
junction resolvase
Length = 497
Score = 372 bits (956), Expect = e-103
Identities = 216/517 (41%), Positives = 311/517 (59%), Gaps = 52/517 (10%)
Query: 8 ITCPVCGKKVAFLKINSHLDKCTEEPKGNREQPTLKTFLSSKRKADEIVIDDVPDNSGVA 67
+ CPVC K V IN HLD + G + F +R + + V+
Sbjct: 7 VQCPVCAKTVTMNDINPHLDSHYSDSSG--PSKPVSPFFKKERYKHHL-------ETNVS 57
Query: 68 LQSTTSCDCQIQGTDTREHKMRKPEWTRPMANNMDLEIKQLQKVQHLPLSEKLRPKSLND 127
+ + + + + T++ K+ + + TRP+A E+ RPKSL++
Sbjct: 58 SHQSATKFIEPEPSPTKKTKLTRRD-TRPLA-------------------ERARPKSLDE 97
Query: 128 YIGQQHILNRETGCLYLYIEKGIIPSMILWGPPGVGKTSLARLLTNTVNIQSDASTKYLL 187
Y+GQ+ ++ E G + IE+ SMILWG G GKT+LARL+ T TK
Sbjct: 98 YVGQEELVG-ERGIIRNLIEQDRCNSMILWGSAGTGKTTLARLIAVT--------TKSRF 148
Query: 188 LETSATKANTTELRSIFDKSKKEYHLTKRMTVLFIDEIHRFNKAQQDLLLPHIENGDIVL 247
+E SAT + R IF+ S+ LT R T++F+DE+HRFN+AQQD+ LP +E G + L
Sbjct: 149 IEISATSTTVADCRKIFEDSQNYLTLTGRKTIIFLDEVHRFNRAQQDIFLPMVEKGLVTL 208
Query: 248 IGATTENPSFQLNNALLSRCQLFVLEKLNDKELKIVLIRAIALLNKYRSLIWKYSAPLKF 307
IGATTENPSF+LN+AL+SRC +FVL+KL +K +L A L ++ S+
Sbjct: 209 IGATTENPSFRLNSALISRCPVFVLKKLTRDNVKKILNHACLLESERLG-----SSMPNV 263
Query: 308 DEDCFSFIYDTAMGDTRRAINLLELLEISTRFKVEGPISLDKVKGLISSNGELRTYYDTH 367
+ +I GD R A+N LE+ S +GP+SL+ +K + + L YD
Sbjct: 264 ETSIIDYISAITDGDARMALNALEM---SIGMLRQGPLSLEDIKDKLVRSSAL---YDRV 317
Query: 368 GENHYDTISAFHKSVRGGDENAALYYLARMLQGGEDPLFIARRMIRIASEDVGLSDPFQL 427
G+ HYDTISAFHKSVRG D +A LYYL RML+ GEDPL++ARRM+RIASED+G++D L
Sbjct: 318 GDVHYDTISAFHKSVRGSDVDATLYYLGRMLESGEDPLYVARRMVRIASEDIGIADNSML 377
Query: 428 PFSVAAHDAVMKVGLPEAELALAQCAVSLSRASKSVELYRGWNKLKAMLKTN-ESGAADC 486
P + + AV +VG+PEA++ LA CAV+L+ A KSV++YR +N +K+ L ++ ++G A+
Sbjct: 378 PLASSTFTAVQQVGMPEADVILAHCAVALALAPKSVDVYRSYNAVKSFLSSHPDAGRAE- 436
Query: 487 PIPLHIRNAPTRMMEELGYGKGYKYNPNFKDGKVLQE 523
IP+HIRNAPT +M++LGY KGYKYNP++KDG V+QE
Sbjct: 437 -IPMHIRNAPTNLMKQLGYHKGYKYNPDYKDGLVMQE 472
>Hs18426902 [L] KOG2028 ATPase related to the helicase subunit of the Holliday
junction resolvase
Length = 665
Score = 358 bits (918), Expect = 2e-98
Identities = 208/449 (46%), Positives = 290/449 (64%), Gaps = 34/449 (7%)
Query: 104 EIKQLQKVQHLPLSEKLRPKSLNDYIGQQHILNRETGCLYLYIEKGIIPSMILWGPPGVG 163
EI+Q+ +Q PL++ +RP +L DY GQ + ++T L +E IPS+ILWGPPG G
Sbjct: 217 EIRQM--LQGKPLADTMRPDTLQDYFGQSKAVGQDT-LLRSLLETNEIPSLILWGPPGCG 273
Query: 164 KTSLARLLTNTVNIQSDASTKYLLLETSATKANTTELRSIFDKSKKEYHLTKRMTVLFID 223
KT+LA ++ + S +++ L SAT A T ++R + +++ E KR T+LFID
Sbjct: 274 KTTLAHIIASN---SKKHSIRFVTL--SATNAKTNDVRDVIKQAQNEKSFFKRKTILFID 328
Query: 224 EIHRFNKAQQDLLLPHIENGDIVLIGATTENPSFQLNNALLSRCQLFVLEKLNDKELKIV 283
EIHRFNK+QQD LPH+E G I LIGATTENPSFQ+N ALLSRC++ VLEKL + + +
Sbjct: 329 EIHRFNKSQQDTFLPHVECGTITLIGATTENPSFQVNAALLSRCRVIVLEKLPVEAMVTI 388
Query: 284 LIRAIALLNKYRSLIWKYSAPLKFDEDCFS----FIYDTAM--------GDTRRAINLLE 331
L+RAI L + + + PL + S FI D A+ GD R +N L+
Sbjct: 389 LMRAINSLGIHVLDSSRPTDPLSHSSNSSSEPAMFIEDKAVDTLAYLSDGDARAGLNGLQ 448
Query: 332 LL---EISTR--FKVEGPISLDKVKGLISSN----GELRTY--YDTHGENHYDTISAFHK 380
L +S+R F + S + LI+ N G R++ YD GE HY+ ISA HK
Sbjct: 449 LAVLARLSSRKMFCKKSGQSYSPSRVLITENDVKEGLQRSHILYDRAGEEHYNCISALHK 508
Query: 381 SVRGGDENAALYYLARMLQGGEDPLFIARRMIRIASEDVGLSDPFQLPFSVAAHDAVMKV 440
S+RG D+NA+LY+LARML+GGEDPL++ARR++R ASED+GL+DP L +VAA+ +
Sbjct: 509 SMRGSDQNASLYWLARMLEGGEDPLYVARRLVRFASEDIGLADPSALTQAVAAYQGCHFI 568
Query: 441 GLPEAELALAQCAVSLSRASKSVELYRGWNKLKAMLKTNESGAADCPIPLHIRNAPTRMM 500
G+PE E+ LAQC V +RA KS+E+Y +N +KA L+ ++ P+PLH+RNAPTR+M
Sbjct: 569 GMPECEVLLAQCVVYFARAPKSIEVYSAYNNVKACLRNHQGPLP--PVPLHLRNAPTRLM 626
Query: 501 EELGYGKGYKYNPNFKDGKVLQEYFPQEL 529
++LGYGKGYKYNP + + V QEY P+EL
Sbjct: 627 KDLGYGKGYKYNPMYSE-PVDQEYLPEEL 654
>At1g24290 [L] KOG2028 ATPase related to the helicase subunit of the Holliday
junction resolvase
Length = 525
Score = 324 bits (830), Expect = 2e-88
Identities = 186/444 (41%), Positives = 268/444 (59%), Gaps = 22/444 (4%)
Query: 112 QHLPLSEKLRPKSLNDYIGQQHILNRETGCLYLYIEKGIIPSMILWGPPGVGKTSLARLL 171
QH PLSE++RP++L+D +GQ H+L+ + L +E +PS++ WGPPG GKTS+A+ L
Sbjct: 99 QHQPLSERMRPRTLDDVVGQDHLLS-PSSLLRSAVESNRLPSIVFWGPPGTGKTSIAKSL 157
Query: 172 TNTVNIQSDASTKYLLLETSATKANTTELRSIFDKSKKEYHLTKRMTVLFIDEIHRFNKA 231
N+ S + Y + SA + ++R + +K+ ++ TVLF+DE+HRFNK+
Sbjct: 158 INS----SKDPSLYRFVSLSAVTSGVKDVRDAVESAKRLNLEGRKRTVLFMDEVHRFNKS 213
Query: 232 QQDLLLPHIENGDIVLIGATTENPSFQLNNALLSRCQLFVLEKLNDKELKIVLIRAIALL 291
QQD LP IE+G I+ IGATTENPSF L LLSRC++ L L ++ +L RA+
Sbjct: 214 QQDTFLPVIEDGSILFIGATTENPSFHLITPLLSRCRVLTLNPLKPNHVETLLRRAVD-- 271
Query: 292 NKYRSLIWKYSAPLKFDEDCFSFIYDTAMGDTRRAINLLELLEI--STRFKVEGPISLDK 349
+ R L ++ D+ F+ + GD R A+N LE+ +TR + +S+D
Sbjct: 272 DSERGL----PNSVEVDDSVIEFLANNCDGDARVALNALEISATMATTRAGTDAVVSIDD 327
Query: 350 VKGLISSNGELRTYYDTHGENHYDTISAFHKSVRGGDENAALYYLARMLQGGEDPLFIAR 409
K + YD GE HY+ ISA HKS+RGGD NAA+Y+LARML+GGE+PL+IAR
Sbjct: 328 AKEALQCK---HLAYDKAGEQHYNLISALHKSMRGGDANAAIYWLARMLEGGEEPLYIAR 384
Query: 410 RMIRIASEDVGLSDPFQLPFSVAAHDAVMKVGLPEAELALAQCAVSLSRASKSVELYRGW 469
R+IR ASED+GL+DP L +VA + A +G+PE + LAQC L+ A KS+ +YR
Sbjct: 385 RLIRFASEDIGLADPSALTQAVACYQASHFLGMPECNVILAQCTAYLALAPKSIAVYRAI 444
Query: 470 NKLKAMLKTNESGAADCPIPLHIRNAPTRMMEELGYGKGYKYNPNFKDGKVLQEYFPQEL 529
+ ++K +S + +PLH+RNAPT++M+ELGYGK Y Y P+ Q Y P L
Sbjct: 445 GAAQKVVK--DSVGQNEGVPLHLRNAPTKLMKELGYGKEYIYPPSDPSSAAGQTYLPPSL 502
Query: 530 LDRCGRKELTFLNGKALGDMEDPD 553
L K L + G A GD +D +
Sbjct: 503 LH---HKFLEWPEG-ASGDFQDQE 522
>Hs18426904 [L] KOG2028 ATPase related to the helicase subunit of the Holliday
junction resolvase
Length = 640
Score = 306 bits (783), Expect = 7e-83
Identities = 189/449 (42%), Positives = 270/449 (60%), Gaps = 59/449 (13%)
Query: 104 EIKQLQKVQHLPLSEKLRPKSLNDYIGQQHILNRETGCLYLYIEKGIIPSMILWGPPGVG 163
EI+Q+ +Q PL++ +RP +L DY GQ + ++T L +E IPS+ILWGPPG G
Sbjct: 217 EIRQM--LQGKPLADTMRPDTLQDYFGQSKAVGQDT-LLRSLLETNEIPSLILWGPPGCG 273
Query: 164 KTSLARLLTNTVNIQSDASTKYLLLETSATKANTTELRSIFDKSKKEYHLTKRMTVLFID 223
KT+LA ++ + S +++ L SAT A T ++R + +++ E KR T+LFID
Sbjct: 274 KTTLAHIIASN---SKKHSIRFVTL--SATNAKTNDVRDVIKQAQNEKSFFKRKTILFID 328
Query: 224 EIHRFNKAQQDLLLPHIENGDIVLIGATTENPSFQLNNALLSRCQLFVLEKLNDKELKIV 283
EIHRFNK+QQ +N ALLSRC++ VLEKL + + +
Sbjct: 329 EIHRFNKSQQ-------------------------VNAALLSRCRVIVLEKLPVEAMVTI 363
Query: 284 LIRAIALLNKYRSLIWKYSAPLKFDEDCFS----FIYDTAM--------GDTRRAINLLE 331
L+RAI L + + + PL + S FI D A+ GD R +N L+
Sbjct: 364 LMRAINSLGIHVLDSSRPTDPLSHSSNSSSEPAMFIEDKAVDTLAYLSDGDARAGLNGLQ 423
Query: 332 LL---EISTR--FKVEGPISLDKVKGLISSN----GELRTY--YDTHGENHYDTISAFHK 380
L +S+R F + S + LI+ N G R++ YD GE HY+ ISA HK
Sbjct: 424 LAVLARLSSRKMFCKKSGQSYSPSRVLITENDVKEGLQRSHILYDRAGEEHYNCISALHK 483
Query: 381 SVRGGDENAALYYLARMLQGGEDPLFIARRMIRIASEDVGLSDPFQLPFSVAAHDAVMKV 440
S+RG D+NA+LY+LARML+GGEDPL++ARR++R ASED+GL+DP L +VAA+ +
Sbjct: 484 SMRGSDQNASLYWLARMLEGGEDPLYVARRLVRFASEDIGLADPSALTQAVAAYQGCHFI 543
Query: 441 GLPEAELALAQCAVSLSRASKSVELYRGWNKLKAMLKTNESGAADCPIPLHIRNAPTRMM 500
G+PE E+ LAQC V +RA KS+E+Y +N +KA L+ ++ P+PLH+RNAPTR+M
Sbjct: 544 GMPECEVLLAQCVVYFARAPKSIEVYSAYNNVKACLRNHQGPLP--PVPLHLRNAPTRLM 601
Query: 501 EELGYGKGYKYNPNFKDGKVLQEYFPQEL 529
++LGYGKGYKYNP + + V QEY P+EL
Sbjct: 602 KDLGYGKGYKYNPMYSE-PVDQEYLPEEL 629
>YNL290w [L] KOG0990 Replication factor C subunit RFC5
Length = 340
Score = 68.2 bits (165), Expect = 3e-11
Identities = 68/286 (23%), Positives = 117/286 (40%), Gaps = 30/286 (10%)
Query: 112 QHLPLSEKLRPKSLNDYIGQQHILNRETGCLYLYIEKGIIPSMILWGPPGVGKTSLARLL 171
++LP EK RP++L++ GQ ++ + ++++G +P ++ +GPPG GKTS L
Sbjct: 11 ENLPWVEKYRPETLDEVYGQNEVITT----VRKFVDEGKLPHLLFYGPPGTGKTSTIVAL 66
Query: 172 TNTVNIQSDASTKYLLLETSATKANTTELRSIFDKSKKEYHLTKRMTVLFIDEIHRFNKA 231
+ + S L L S + I D + +K ++ +DE A
Sbjct: 67 AREI-YGKNYSNMVLELNASDDRGIDVVRNQIKDFASTRQIFSKGFKLIILDEADAMTNA 125
Query: 232 QQDLLLPHIENGDIVLIGATTENPSFQLNNALLSRCQLFVLEKLNDKELKIVLIRAIALL 291
Q+ L IE N + +L ALLSRC F + L + ++ R IA +
Sbjct: 126 AQNALRRVIERYTKNTRFCVLANYAHKLTPALLSRCTRFRFQPLPQEAIE----RRIANV 181
Query: 292 NKYRSLIWKYSAPLKFDEDCFSFIYDTAMGDTRRAINLLELLEISTRFKVEGPISLDKVK 351
+ LK + + + + GD RR +N+L+ + + E IS D +
Sbjct: 182 LVHEK--------LKLSPNAEKALIELSNGDMRRVLNVLQSCKATLDNPDEDEISDDVI- 232
Query: 352 GLISSNGELRTYYDTHGENHYDTISAFHKSVRGGDENAALYYLARM 397
Y+ G + A KS+ D A Y L ++
Sbjct: 233 ------------YECCGAPRPSDLKAVLKSILEDDWGTAHYTLNKV 266
>YOL094c [L] KOG0991 Replication factor C subunit RFC2
Length = 323
Score = 66.2 bits (160), Expect = 1e-10
Identities = 72/255 (28%), Positives = 112/255 (43%), Gaps = 26/255 (10%)
Query: 114 LPLSEKLRPKSLNDYIGQQHILNRETGCLYLYIEKGIIPSMILWGPPGVGKTSLARLLTN 173
LP EK RP+ L+D +G + ++R L + G +P MI+ G PG+GKT+ L +
Sbjct: 9 LPWVEKYRPQVLSDIVGNKETIDR----LQQIAKDGNMPHMIISGMPGIGKTTSVHCLAH 64
Query: 174 TVNIQSDASTKYLLLETSATKANTTELRSIFDKSKKEYHLTK-RMTVLFIDEIHRFNKAQ 232
+ +S A L L S + I ++K+ HL + ++ +DE
Sbjct: 65 ELLGRSYAD-GVLELNASDDRGIDVVRNQIKHFAQKKLHLPPGKHKIVILDEADSMTAGA 123
Query: 233 QDLLLPHIENGDIVLIGATTENPSFQLNNALLSRCQLFVLEKLNDKELKIVLIRAIALLN 292
Q L +E A N S ++ L SRC + KL+D+++ L++ I L
Sbjct: 124 QQALRRTMELYSNSTRFAFACNQSNKIIEPLQSRCAILRYSKLSDEDVLKRLLQIIKL-- 181
Query: 293 KYRSLIWKYSAPLKFDEDCFSFIYDTAMGDTRRAINLLE-------LLEISTRFK-VEGP 344
+K+ D I TA GD R+AIN L+ L+ FK V+ P
Sbjct: 182 ----------EDVKYTNDGLEAIIFTAEGDMRQAINNLQSTVAGHGLVNADNVFKIVDSP 231
Query: 345 ISLDKVKGLISSNGE 359
L K L++SN E
Sbjct: 232 HPLIVKKMLLASNLE 246
>7292439 [L] KOG0991 Replication factor C subunit RFC2
Length = 331
Score = 63.9 bits (154), Expect = 6e-10
Identities = 60/225 (26%), Positives = 96/225 (42%), Gaps = 22/225 (9%)
Query: 110 KVQHLPLSEKLRPKSLNDYIGQQHILNRETGCLYLYIEKGIIPSMILWGPPGVGKTSLAR 169
K HLP EK RP + +G + + R L ++ +G P++I+ GPPGVGKT+ +
Sbjct: 12 KRSHLPWIEKYRPVKFKEIVGNEDTVAR----LSVFATQGNAPNIIIAGPPGVGKTTTIQ 67
Query: 170 LLTNTVNIQSDASTKYLLLETSATKANTTELRSIFDKSKKEYHLT---KRMTVLFIDEIH 226
L I S K +LE +A+ ++ K + +T R ++ +DE
Sbjct: 68 CL---ARILLGDSYKEAVLELNASNERGIDVVRNKIKMFAQQKVTLPRGRHKIVILDEAD 124
Query: 227 RFNKAQQDLLLPHIENGDIVLIGATTENPSFQLNNALLSRCQLFVLEKLNDKELKIVLIR 286
+ Q L +E A N S ++ + SRC + KL+D ++ LI
Sbjct: 125 SMTEGAQQALRRTMEIYSSTTRFALACNTSEKIIEPIQSRCAMLRFTKLSDAQVLAKLIE 184
Query: 287 AIALLNKYRSLIWKYSAPLKFDEDCFSFIYDTAMGDTRRAINLLE 331
W+ L + ED I TA GD R+ +N L+
Sbjct: 185 VAK---------WE---KLNYTEDGLEAIVFTAQGDMRQGLNNLQ 217
>ECU02g0290 [L] KOG0990 Replication factor C subunit RFC5
Length = 305
Score = 63.5 bits (153), Expect = 8e-10
Identities = 58/228 (25%), Positives = 101/228 (43%), Gaps = 34/228 (14%)
Query: 113 HLPLSEKLRPKSLNDYIGQQHILNRETGCLYLYIEKGIIPSMILWGPPGVGKTSLARLLT 172
H L+EK RP SL + +G + +++ L G IP+M+ +GPPG GKT+ R +
Sbjct: 2 HQQLTEKYRPGSLLEVVGNREVVSS----LQSISSAGRIPNMLFYGPPGTGKTTSIRAIA 57
Query: 173 NTVNIQSDASTKYLLLETSATKANTTELRSI--FDKSKKEYHLT--KRMTVLFIDEIHRF 228
N L TS + N ++ R I ++ KE+ T K M ++ +DE
Sbjct: 58 NN------------LPRTSVLELNASDERGIATVRETIKEFASTYSKTMKLVILDEADMM 105
Query: 229 NKAQQDLLLPHIENGDIVLIGATTENPSFQLNNALLSRCQLFVLEKLNDKELKIVLIRAI 288
++ Q+ L IE+ N ++ + +LSRC F + D E
Sbjct: 106 SRDAQNALRRIIEDFSANTRFCLIANHLRKIISPILSRCTKFRFGPIGDTE--------- 156
Query: 289 ALLNKYRSLIWKYSAPLKFDEDCFSFIYDTAMGDTRRAINLLELLEIS 336
N+ + + S +K+ + + +MGD R+A+N ++ + S
Sbjct: 157 ---NRIEEICKRES--IKYTPEGIKAVSRISMGDMRKAVNDIQGISAS 199
>Hs4506487 [L] KOG0991 Replication factor C subunit RFC2
Length = 354
Score = 63.2 bits (152), Expect = 1e-09
Identities = 58/221 (26%), Positives = 101/221 (45%), Gaps = 22/221 (9%)
Query: 114 LPLSEKLRPKSLNDYIGQQHILNRETGCLYLYIEKGIIPSMILWGPPGVGKTSLARLLTN 173
LP EK RP LN+ +G + ++R L ++ +G +P++I+ GPPG GKT+ L
Sbjct: 36 LPWVEKYRPVKLNEIVGNEDTVSR----LEVFAREGNVPNIIIAGPPGTGKTTSILCLAR 91
Query: 174 TVNIQSDASTKYLLLETSATKANTTEL--RSIFDKSKKEYHLTK-RMTVLFIDEIHRFNK 230
+ + K +LE +A+ ++ I ++++ L K R ++ +DE
Sbjct: 92 AL---LGPALKDAMLELNASNDRGIDVVRNKIKMFAQQKVTLPKGRHKIIILDEADSMTD 148
Query: 231 AQQDLLLPHIENGDIVLIGATTENPSFQLNNALLSRCQLFVLEKLNDKELKIVLIRAIAL 290
Q L +E A N S ++ + SRC + KL D + +L R + +
Sbjct: 149 GAQQALRRTMEIYSKTTRFALACNASDKIIEPIQSRCAVLRYTKLTDAQ---ILTRLMNV 205
Query: 291 LNKYRSLIWKYSAPLKFDEDCFSFIYDTAMGDTRRAINLLE 331
+ K R + + +D I TA GD R+A+N L+
Sbjct: 206 IEKER---------VPYTDDGLEAIIFTAQGDMRQALNNLQ 237
>Hs6677723 [L] KOG0990 Replication factor C subunit RFC5
Length = 340
Score = 62.4 bits (150), Expect = 2e-09
Identities = 61/232 (26%), Positives = 99/232 (42%), Gaps = 36/232 (15%)
Query: 110 KVQHLPLSEKLRPKSLNDYIGQQHILNRETGCLYLYIEKGIIPSMILWGPPGVGKTSLAR 169
K+++LP EK RP++LND I Q IL+ + +I + +P ++L+GPPG GKTS
Sbjct: 16 KIRNLPWVEKYRPQTLNDLISHQDILS----TIQKFINEDRLPHLLLYGPPGTGKTS--T 69
Query: 170 LLTNTVNIQSDASTKYLLLETSATKANTTEL--RSIFDKSKKEYHLTKRMTVLFIDEIHR 227
+L + D ++LE +A+ ++ I + K ++ +DE
Sbjct: 70 ILACAKQLYKDKEFGSMVLELNASDDRGIDIIRGPILSFASTRTIFKKGFKLVILDEADA 129
Query: 228 FNKAQQDLLLPHIENGDIVLIGATTENPSF--------QLNNALLSRCQLFVLEKLNDKE 279
+ Q+ L IE TEN F ++ AL SRC F L E
Sbjct: 130 MTQDAQNALRRVIEK--------FTENTRFCLICNYLSKIIPALQSRCTRFRFGPLT-PE 180
Query: 280 LKIVLIRAIALLNKYRSLIWKYSAPLKFDEDCFSFIYDTAMGDTRRAINLLE 331
L + + + K + ED + + GD RRA+N+L+
Sbjct: 181 LMVPRLEHVVEEEK-----------VDISEDGMKALVTLSSGDMRRALNILQ 221
>CE17139 [L] KOG0991 Replication factor C subunit RFC2
Length = 334
Score = 60.5 bits (145), Expect = 7e-09
Identities = 59/226 (26%), Positives = 99/226 (43%), Gaps = 22/226 (9%)
Query: 109 QKVQHLPLSEKLRPKSLNDYIGQQHILNRETGCLYLYIEKGIIPSMILWGPPGVGKTSLA 168
+K Q P EK RPK L D +G ++I+ R L + +G +P+++L GPPG GKT+
Sbjct: 5 EKQQLAPWVEKYRPKVLADIVGNENIVER----LKVIGHEGNVPNIVLSGPPGCGKTTSV 60
Query: 169 RLLTNTVNIQSDASTKYLLLETSATKANTTELRSIFDKSKKEYHLT---KRMTVLFIDEI 225
L + K +LE +A+ ++ K+ + +T R ++ +DE
Sbjct: 61 WALAREL---LGDKVKEAVLELNASDERGIDVVRHRIKTFAQTKVTLPEGRHKIIILDEA 117
Query: 226 HRFNKAQQDLLLPHIENGDIVLIGATTENPSFQLNNALLSRCQLFVLEKLNDKELKIVLI 285
Q L +E A N S ++ + SRC L KL+ +L + +
Sbjct: 118 DSMTDGAQQALRRTMEMYTKTTRFALACNQSEKIIEPIQSRCALLRYTKLSPVQL-LTRV 176
Query: 286 RAIALLNKYRSLIWKYSAPLKFDEDCFSFIYDTAMGDTRRAINLLE 331
+ +A K + +D+ I TA GD R+A+N L+
Sbjct: 177 KEVAKAEK-----------VNYDDGGLEAILFTAQGDMRQALNNLQ 211
>At4g24790 [L] KOG0989 Replication factor C subunit RFC4
Length = 815
Score = 58.9 bits (141), Expect = 2e-08
Identities = 68/266 (25%), Positives = 110/266 (40%), Gaps = 45/266 (16%)
Query: 116 LSEKLRPKSLNDYIGQQHILNRETGCLYLYIEKGIIPSMILW-GPPGVGKTSLARLLTNT 174
LS+K RPKS ++ +GQ+ ++ CL I +G I S+ L+ GP G GKTS +++
Sbjct: 241 LSQKFRPKSFDELVGQEVVVK----CLLSTILRGRITSVYLFHGPRGTGKTSTSKIFAAA 296
Query: 175 VNIQSDAS-----------TKYL------LLETSATKANTTELRSIFDKSKKEYHLTKRM 217
+N S A+ Y ++ET + K N KS ++ R
Sbjct: 297 LNCLSQAAHSRPCGLCSECKSYFSGRGRDVMETDSGKLNRPSYLRSLIKSASLPPVSSRF 356
Query: 218 TVLFIDEIHRFNKAQQDLLLPHIEN--GDIVLIGATTENPSFQLNNALLSRCQLFVLEKL 275
V IDE + LL ++N V I T+E N +LSR Q + K+
Sbjct: 357 KVFIIDECQLLCQETWGTLLNSLDNFSQHSVFILVTSELEKLPRN--VLSRSQKYHFSKV 414
Query: 276 NDKELKIVLIRAIALLNKYRSLIWKYSAPLKFDEDCFSFIYDTAMGDTRRAINLLELLEI 335
D ++ L + + FD+ FI + G R A +L+ L +
Sbjct: 415 CDADISTKLAKIC------------IEEGIDFDQGAVDFIASKSDGSLRDAEIMLDQLSL 462
Query: 336 -------STRFKVEGPISLDKVKGLI 354
S +K+ G +S D++ L+
Sbjct: 463 LGKRITTSLAYKLIGVVSDDELLDLL 488
>At1g63160 [L] KOG0991 Replication factor C subunit RFC2
Length = 333
Score = 52.8 bits (125), Expect = 1e-06
Identities = 55/218 (25%), Positives = 93/218 (42%), Gaps = 18/218 (8%)
Query: 115 PLSEKLRPKSLNDYIGQQHILNRETGCLYLYIEKGIIPSMILWGPPGVGKTSLARLLTNT 174
P EK RP + D +G + ++R L + G +P++IL GPPG GKT+ L +
Sbjct: 16 PWVEKYRPSKVVDIVGNEDAVSR----LQVIARDGNMPNLILSGPPGTGKTTSILALAHE 71
Query: 175 VNIQSDASTKYLLLETSATKANTTELRSIFDKSKKEYHLTK-RMTVLFIDEIHRFNKAQQ 233
+ + ++ L L S + I ++K+ L R V+ +DE Q
Sbjct: 72 L-LGTNYKEAVLELNASDDRGIDVVRNKIKMFAQKKVTLPPGRHKVVILDEADSMTSGAQ 130
Query: 234 DLLLPHIENGDIVLIGATTENPSFQLNNALLSRCQLFVLEKLNDKELKIVLIRAIALLNK 293
L IE A N S ++ + SRC L +L+D+++ L+ +A
Sbjct: 131 QALRRTIEIYSNSTRFALACNTSAKIIEPIQSRCALVRFSRLSDQQILGRLLVVVA---- 186
Query: 294 YRSLIWKYSAPLKFDEDCFSFIYDTAMGDTRRAINLLE 331
+ + + + I TA GD R+A+N L+
Sbjct: 187 --------AEKVPYVPEGLEAIIFTADGDMRQALNNLQ 216
>YJR068w [L] KOG0989 Replication factor C subunit RFC4
Length = 353
Score = 52.4 bits (124), Expect = 2e-06
Identities = 70/305 (22%), Positives = 115/305 (36%), Gaps = 42/305 (13%)
Query: 109 QKVQHLPLSEKLRPKSLNDYIGQQHILNRETGCLYLYIEKGIIPSMILWGPPGVGKTSLA 168
Q + P EK RPK+L++ Q H + L ++ +P M+ +GPPG GKTS
Sbjct: 20 QSLAQQPWVEKYRPKNLDEVTAQDHAVT----VLKKTLKSANLPHMLFYGPPGTGKTS-- 73
Query: 169 RLLTNTVNIQSDASTKYLLLETSATKANTTEL---------RSIFDKSKK---EYHLTKR 216
+L T + K +LE +A+ + R K K E +
Sbjct: 74 TILALTKELYGPDLMKSRILELNASDERGISIVREKVKNFARLTVSKPSKHDLENYPCPP 133
Query: 217 MTVLFIDEIHRFNKAQQDLLLPHIENGDIVLIGATTENPSFQLNNALLSRCQLFVLEKLN 276
++ +DE Q L +E V N ++ + L SRC F + L
Sbjct: 134 YKIIILDEADSMTADAQSALRRTMETYSGVTRFCLICNYVTRIIDPLASRCSKFRFKAL- 192
Query: 277 DKELKIVLIRAIALLNKYRSLIWKYSAPLKFDEDCFSFIYDTAMGDTRRAINLLELLEIS 336
D I +R I+ +K D+ I D + GD RR I LL+
Sbjct: 193 DASNAIDRLRFIS-----------EQENVKCDDGVLERILDISAGDLRRGITLLQSASKG 241
Query: 337 TRFKVEGPISLDKVKGLISSNGELRTYYDTHGENHYDTISAFHKSVRGGDENAALYYLAR 396
++ +G K + S+ E + G +D + + V+ GD + Y+
Sbjct: 242 AQYLGDG-------KNITSTQVE-----ELAGVVPHDILIEIVEKVKSGDFDEIKKYVNT 289
Query: 397 MLQGG 401
++ G
Sbjct: 290 FMKSG 294
>SPAC1687.03c [L] KOG0991 Replication factor C subunit RFC2
Length = 342
Score = 51.6 bits (122), Expect = 3e-06
Identities = 53/221 (23%), Positives = 97/221 (42%), Gaps = 22/221 (9%)
Query: 114 LPLSEKLRPKSLNDYIGQQHILNRETGCLYLYIEKGIIPSMILWGPPGVGKTSLARLLTN 173
LP EK RP L+D +G + ++R L + ++G +P +++ G PG+GKT+ L +
Sbjct: 21 LPWVEKYRPIVLDDIVGNEETIDR----LKVIAKEGNMPHLVISGMPGIGKTTSILCLAH 76
Query: 174 TVNIQSDASTKYLLLETSATKANTTEL---RSIFDKSKKEYHLTKRMTVLFIDEIHRFNK 230
+ + K +LE +A+ ++ R KK R ++ +DE
Sbjct: 77 AL---LGPAYKEGVLELNASDERGIDVVRNRIKAFAQKKVILPPGRHKIIILDEADSMTA 133
Query: 231 AQQDLLLPHIENGDIVLIGATTENPSFQLNNALLSRCQLFVLEKLNDKELKIVLIRAIAL 290
Q L +E A N S ++ + SRC + +L D++ VL R + +
Sbjct: 134 GAQQALRRTMEIYSNTTRFALACNQSNKIIEPIQSRCAILRYSRLTDQQ---VLQRLLNI 190
Query: 291 LNKYRSLIWKYSAPLKFDEDCFSFIYDTAMGDTRRAINLLE 331
+ + + +D + + TA GD R+A+N L+
Sbjct: 191 CK---------AEKVNYTDDGLAALIMTAEGDMRQAVNNLQ 222
>At1g14460 [L] KOG0989 Replication factor C subunit RFC4
Length = 1102
Score = 50.1 bits (118), Expect = 9e-06
Identities = 71/273 (26%), Positives = 113/273 (41%), Gaps = 57/273 (20%)
Query: 116 LSEKLRPKSLNDYIGQQHILNRETGCLYLYIEKGIIPSMILW-GPPGVGKTSLARLLTNT 174
LS+K +P ++ IGQ ++ L ++KG + + L+ GP G GKTS AR+L+
Sbjct: 424 LSQKYKPMFFDELIGQSIVVQS----LMNAVKKGRVAHVYLFQGPRGTGKTSTARILSAA 479
Query: 175 VNIQSDASTKYL-------------------LLETSATKANTTE-----LRSIFDKSKKE 210
+N D T+ + LLE A K N E L+ + + +
Sbjct: 480 LN--CDVVTEEMKPCGYCKECSDYMLGKSRDLLELDAGKKNGAEKVRYLLKKLLTLAPQS 537
Query: 211 YHLTKRMTVLFIDEIHRFNKAQQDLLLPHIEN--GDIVLIGATTENPSFQLNNALLSRCQ 268
++R V IDE H LL +EN V + TT+ + + + SRCQ
Sbjct: 538 ---SQRYKVFVIDECHLLPSRTWLSLLKFLENPLQKFVFVCITTDLDN--VPRTIQSRCQ 592
Query: 269 LFVLEKLNDKELKIVLIRAIALLNKYRSLIWKYSAPLKFDEDCFSFIYDTAMGDTRRAIN 328
++ K+ D ++ +V +R IA L + I A G R A
Sbjct: 593 KYIFNKVRDGDI-VVRLRKIA-----------SDENLDVESQALDLIALNADGSLRDAET 640
Query: 329 LLELLEI-STRFKVE------GPISLDKVKGLI 354
+LE L + R V+ G +S DK+ L+
Sbjct: 641 MLEQLSLMGKRITVDLVNELVGVVSDDKLLELL 673
Database: KOG eukaryal database 04/03
Posted date: Apr 14, 2003 1:07 PM
Number of letters in database: 30,389,216
Number of sequences in database: 60,738
Lambda K H
0.318 0.135 0.392
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 33,575,471
Number of Sequences: 60738
Number of extensions: 1458732
Number of successful extensions: 4636
Number of sequences better than 1.0e-05: 17
Number of HSP's better than 0.0 without gapping: 5
Number of HSP's successfully gapped in prelim test: 12
Number of HSP's that attempted gapping in prelim test: 4583
Number of HSP's gapped (non-prelim): 21
length of query: 559
length of database: 30,389,216
effective HSP length: 112
effective length of query: 447
effective length of database: 23,586,560
effective search space: 10543192320
effective search space used: 10543192320
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)