ORF STATUS Function Best COG Functional category Pathways and functional systems
r_klactIV4783 good F KOG1355 Nucleotide transport and metabolism Adenylosuccinate synthase
Only best alignment is shown:
BLASTP 2.2.3 [May-13-2002]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= r_klactIV4783 1636053 1634758 -432
(432 letters)
Database: KOG eukaryal database 04/03
60,738 sequences; 30,389,216 total letters
Searching..................................................done
Color Key for Alignment Scores: 
Score E
Sequences producing significant alignments: (bits) Value
YNL220w [F] KOG1355 Adenylosuccinate synthase 704 0.0
SPAC144.03 [F] KOG1355 Adenylosuccinate synthase 531 e-151
7300663 [F] KOG1355 Adenylosuccinate synthase 474 e-134
Hs4557271 [F] KOG1355 Adenylosuccinate synthase 455 e-128
Hs20538560 [F] KOG1355 Adenylosuccinate synthase 455 e-128
At3g57610 [F] KOG1355 Adenylosuccinate synthase 416 e-116
CE08630 [F] KOG1355 Adenylosuccinate synthase 414 e-115
Hs22049791 [F] KOG1355 Adenylosuccinate synthase 413 e-115
Hs18587061_2 [F] KOG1355 Adenylosuccinate synthase 105 1e-22
>YNL220w [F] KOG1355 Adenylosuccinate synthase
Length = 433
Score = 704 bits (1817), Expect = 0.0
Identities = 345/432 (79%), Positives = 376/432 (86%)
Query: 1 MVNVVLGSQWGDEGKGKLVDLLVGEYDIVARSAGGNNAGHTIVVNGVKYDFHMLPSGLVN 60
MVNVVLGSQWGDEGKGKLVDLLVG+YDIVAR AGGNNAGHTIVV+GVKYDFHMLPSGLVN
Sbjct: 1 MVNVVLGSQWGDEGKGKLVDLLVGKYDIVARCAGGNNAGHTIVVDGVKYDFHMLPSGLVN 60
Query: 61 PNCQNLIGNGVVIHVPSFFEELKSLEAKGLKNAKGRLFISSRAHLVFDFHQRTDKLRELE 120
PNCQNL+GNGVVIHVPSFF+EL++LEAKGLKNA+ RLF+SSRAHLVFDFHQ TDKLRELE
Sbjct: 61 PNCQNLLGNGVVIHVPSFFKELETLEAKGLKNARSRLFVSSRAHLVFDFHQVTDKLRELE 120
Query: 121 LSGASKDXXXXXXXXXXXXPTYSTKASRSGLRVHHLVNDDPQAWEVFETRYRRLVETRQQ 180
LSG SKD PTYSTKASRSGLRVHHLVND P AWE F RY+RL+ETR+Q
Sbjct: 121 LSGRSKDGKNIGTTGKGIGPTYSTKASRSGLRVHHLVNDQPGAWEEFVARYKRLLETRRQ 180
Query: 181 RYGSFDYDPEEELQRYKSYREQLKPFVVDSVNFMHDAIKKNKKILVEGANALMLDIDFGT 240
RYG F+YD E +L YK REQLKPFVVDSV FMH+AI+ KKILVEGANALMLDIDFGT
Sbjct: 181 RYGDFEYDFEAKLAEYKKLREQLKPFVVDSVVFMHNAIEAKKKILVEGANALMLDIDFGT 240
Query: 241 YPYVTSSNXXXXXXXXXXXXPPRTIKEVFGVVKAYTTRVGEGPFPTEQLNEDGEKLQNIG 300
YPYVTSSN PPRTI E++GVVKAYTTRVGEGPFPTEQLNE+GEKLQ IG
Sbjct: 241 YPYVTSSNTGIGGVLTGLGIPPRTIDEIYGVVKAYTTRVGEGPFPTEQLNENGEKLQTIG 300
Query: 301 AEFGVTTGRKRRCGWLDLVVLKYSNLINGYTSLNITKLDVLDTFKEIKVGVSYSVDGKKL 360
AEFGVTTGRKRRCGWLDLVVLKYS LINGYTSLNITKLDVLDTFKEI VG+SYS+ GKKL
Sbjct: 301 AEFGVTTGRKRRCGWLDLVVLKYSTLINGYTSLNITKLDVLDTFKEIPVGISYSIQGKKL 360
Query: 361 ESFPEDLLTLAKVEVEYVTLPGWEEDISKITNYEDLPENAQKYLKFIEDFVEVPIQWVGT 420
+ FPEDL L KVEVEY LPGW++DI+KIT YEDLPENA+KYLK+IEDFV VP++WVGT
Sbjct: 361 DLFPEDLNILGKVEVEYKVLPGWDQDITKITKYEDLPENAKKYLKYIEDFVGVPVEWVGT 420
Query: 421 GPARDAMVHKEI 432
GPAR++M+HKEI
Sbjct: 421 GPARESMLHKEI 432
>SPAC144.03 [F] KOG1355 Adenylosuccinate synthase
Length = 434
Score = 531 bits (1369), Expect = e-151
Identities = 261/430 (60%), Positives = 321/430 (73%), Gaps = 11/430 (2%)
Query: 2 VNVVLGSQWGDEGKGKLVDLLVGEYDIVARSAGGNNAGHTIVVNGVKYDFHMLPSGLVNP 61
+ VVLGSQWGDEGKGKLVD+L D+ AR GGNNAGHTIV NGV YDFH+LPSGLVNP
Sbjct: 16 ITVVLGSQWGDEGKGKLVDILCDNVDVCARCQGGNNAGHTIVANGVTYDFHILPSGLVNP 75
Query: 62 NCQNLIGNGVVIHVPSFFEELKSLEAKGLKNAKGRLFISSRAHLVFDFHQRTDKLRELEL 121
CQNLIG+GVV+++P+FF EL+ LE KGLK + R+FIS RAHLVFD+HQR D L E EL
Sbjct: 76 KCQNLIGSGVVVYLPAFFSELEKLEQKGLK-CRDRIFISDRAHLVFDYHQRADALNEAEL 134
Query: 122 SGASKDXXXXXXXXXXXXPTYSTKASRSGLRVHHLVNDDPQAWEVFETRYRRLVETRQQR 181
S P YSTKA+RSG+RVHHL + W FE RYR+ V Q+R
Sbjct: 135 GKQS-----IGTTGKGIGPAYSTKATRSGIRVHHLYH-----WAEFEARYRKNVADLQKR 184
Query: 182 YGSFDYDPEEELQRYKSYREQLKPFVVDSVNFMHDAIKKNKKILVEGANALMLDIDFGTY 241
YG+F+YD E EL RYK ++LKPFV+D+V FM++A++ K+ILVEGANALMLD+DFGTY
Sbjct: 185 YGAFEYDVEAELIRYKELAQRLKPFVIDAVAFMYEALQSKKRILVEGANALMLDLDFGTY 244
Query: 242 PYVTSSNXXXXXXXXXXXXPPRTIKEVFGVVKAYTTRVGEGPFPTEQLNEDGEKLQNIGA 301
P+VTSSN PP+ I GVVKAYTTRVG GPFPTEQLNE G+ LQ++G
Sbjct: 245 PFVTSSNTTVGGVCTGLGVPPQRIANSIGVVKAYTTRVGAGPFPTEQLNEIGDHLQSVGR 304
Query: 302 EFGVTTGRKRRCGWLDLVVLKYSNLINGYTSLNITKLDVLDTFKEIKVGVSYSVDGKKLE 361
E GVTTGRKRRCGWLDLVV+KYS +INGYTSLN+TKLD+LD EIKV V+Y ++GK++E
Sbjct: 305 EVGVTTGRKRRCGWLDLVVVKYSTMINGYTSLNLTKLDILDALDEIKVAVAYIINGKRIE 364
Query: 362 SFPEDLLTLAKVEVEYVTLPGWEEDISKITNYEDLPENAQKYLKFIEDFVEVPIQWVGTG 421
+FP DL +L + E+ Y T PGW+ + IT+++ +PENA+KY++FIE FV VPI ++G G
Sbjct: 365 TFPADLDSLEEAEIVYETFPGWKVPTTGITHWDQMPENAKKYIEFIEKFVGVPITFIGVG 424
Query: 422 PARDAMVHKE 431
P RD M+ KE
Sbjct: 425 PGRDEMLVKE 434
>7300663 [F] KOG1355 Adenylosuccinate synthase
Length = 447
Score = 474 bits (1221), Expect = e-134
Identities = 228/429 (53%), Positives = 307/429 (71%), Gaps = 10/429 (2%)
Query: 2 VNVVLGSQWGDEGKGKLVDLLVGEYDIVARSAGGNNAGHTIVVNGVKYDFHMLPSGLVNP 61
V+VVLG+QWGDEGKGK+VD+L + DIV R GGNNAGHT+V NG ++DFH+LPSG+VN
Sbjct: 26 VDVVLGAQWGDEGKGKVVDMLASDVDIVCRCQGGNNAGHTVVANGTEFDFHLLPSGVVNE 85
Query: 62 NCQNLIGNGVVIHVPSFFEELKSLEAKGLKNAKGRLFISSRAHLVFDFHQRTDKLRELEL 121
C ++IGNGVVIH+PS F+E+ EAKGL++ + RL IS RAHLVFDFHQ D ++E E
Sbjct: 86 KCVSVIGNGVVIHLPSLFDEVLKNEAKGLQHLENRLIISDRAHLVFDFHQHVDGMQEAEK 145
Query: 122 SGASKDXXXXXXXXXXXXPTYSTKASRSGLRVHHLVNDDPQAWEVFETRYRRLVETRQQR 181
G S P YS+KA+R+G+RV L+ D + +F +++ +V T +
Sbjct: 146 GGKS-----LGTTKKGIGPAYSSKATRNGIRVGELLGD----FNLFSEKFKSIVATHVRL 196
Query: 182 YGSFDYDPEEELQRYKSYREQLKPFVVDSVNFMHDAIKKNKKILVEGANALMLDIDFGTY 241
+ S + D E EL RYK Y ++++P+V D++ F+H A++ K ILVEGANA MLDIDFGTY
Sbjct: 197 FPSINVDVEAELARYKDYADKVRPYVKDTICFLHTALRNGKTILVEGANAAMLDIDFGTY 256
Query: 242 PYVTSSNXXXXXXXXXXXXPPRTIKEVFGVVKAYTTRVGEGPFPTEQLNEDGEKLQNIGA 301
PYVTSSN PP+TI EV GVVKAYTTRVG+GPFPTEQLN+ G+ LQ G
Sbjct: 257 PYVTSSNCSIGGVLTGLGLPPQTIGEVIGVVKAYTTRVGDGPFPTEQLNDIGDLLQTRGF 316
Query: 302 EFGVTTGRKRRCGWLDLVVLKYSNLINGYTSLNITKLDVLDTFKEIKVGVSY-SVDGKKL 360
E GVTT RKRRCGWLD+ +LKY++L+NGYT + +TKLD+LDT EIKV V+Y +G+KL
Sbjct: 317 EVGVTTKRKRRCGWLDIPLLKYTSLVNGYTCICLTKLDILDTLPEIKVAVAYKKPNGEKL 376
Query: 361 ESFPEDLLTLAKVEVEYVTLPGWEEDISKITNYEDLPENAQKYLKFIEDFVEVPIQWVGT 420
+ FP + L +EVEY LPGW+ ++ N+++LPENAQ Y++F+E + VP++WVG
Sbjct: 377 DHFPGTIAELGNIEVEYAVLPGWQTSTEEVRNFKELPENAQSYVRFLESELSVPVRWVGV 436
Query: 421 GPARDAMVH 429
G R+++++
Sbjct: 437 GKGRESIIN 445
>Hs4557271 [F] KOG1355 Adenylosuccinate synthase
Length = 455
Score = 455 bits (1170), Expect = e-128
Identities = 231/430 (53%), Positives = 302/430 (69%), Gaps = 9/430 (2%)
Query: 2 VNVVLGSQWGDEGKGKLVDLLVGEYDIVARSAGGNNAGHTIVVNGVKYDFHMLPSGLVNP 61
V VVLG+QWGDEGKGK+VDLL + DIV R GGNNAGHT+VV+ V+YDFH+LPSG++NP
Sbjct: 29 VTVVLGAQWGDEGKGKVVDLLAQDADIVCRCQGGNNAGHTVVVDSVEYDFHLLPSGIINP 88
Query: 62 NCQNLIGNGVVIHVPSFFEELKS--LEAKGLKNAKGRLFISSRAHLVFDFHQRTDKLREL 119
N IGNGVVIH+P FEE + + KGL+ + RL IS RAH+VFDFHQ D ++E
Sbjct: 89 NVTAFIGNGVVIHLPGLFEEAEKNVQKGKGLEGWEKRLIISDRAHIVFDFHQAADGIQEQ 148
Query: 120 ELSGASKDXXXXXXXXXXXXPTYSTKASRSGLRVHHLVNDDPQAWEVFETRYRRLVETRQ 179
+ + P YS+KA+RSGLR+ LV+D ++ F R++ L +
Sbjct: 149 QRQ--EQAGKNLGTTKKGIGPVYSSKAARSGLRMCDLVSD----FDGFSERFKVLANQYK 202
Query: 180 QRYGSFDYDPEEELQRYKSYREQLKPFVVDSVNFMHDAIK-KNKKILVEGANALMLDIDF 238
Y + + D E ELQ+ K Y E++KP V D V F+++A+ KKILVEGANA +LDIDF
Sbjct: 203 SIYPTLEIDIEGELQKLKGYMEKIKPMVRDGVYFLYEALHGPPKKILVEGANAALLDIDF 262
Query: 239 GTYPYVTSSNXXXXXXXXXXXXPPRTIKEVFGVVKAYTTRVGEGPFPTEQLNEDGEKLQN 298
GTYP+VTSSN PP+ + EV+GVVKAYTTRVG G FPTEQ NE GE LQ
Sbjct: 263 GTYPFVTSSNCTVGGVCTGLGMPPQNVGEVYGVVKAYTTRVGIGAFPTEQDNEIGELLQT 322
Query: 299 IGAEFGVTTGRKRRCGWLDLVVLKYSNLINGYTSLNITKLDVLDTFKEIKVGVSYSVDGK 358
G EFGVTTGRKRRCGWLDLV+LKY+++ING+T+L +TKLD+LD F EIKVGV+Y +DG+
Sbjct: 323 RGREFGVTTGRKRRCGWLDLVLLKYAHMINGFTALALTKLDILDMFTEIKVGVAYKLDGE 382
Query: 359 KLESFPEDLLTLAKVEVEYVTLPGWEEDISKITNYEDLPENAQKYLKFIEDFVEVPIQWV 418
+ P + L KVEV+Y TLPGW DIS +++LP NAQ Y++FIED +++P++W+
Sbjct: 383 IIPHIPANQEVLNKVEVQYKTLPGWNTDISNARAFKELPVNAQNYVRFIEDELQIPVKWI 442
Query: 419 GTGPARDAMV 428
G G +R++M+
Sbjct: 443 GVGKSRESMI 452
>Hs20538560 [F] KOG1355 Adenylosuccinate synthase
Length = 456
Score = 455 bits (1170), Expect = e-128
Identities = 231/430 (53%), Positives = 302/430 (69%), Gaps = 9/430 (2%)
Query: 2 VNVVLGSQWGDEGKGKLVDLLVGEYDIVARSAGGNNAGHTIVVNGVKYDFHMLPSGLVNP 61
V VVLG+QWGDEGKGK+VDLL + DIV R GGNNAGHT+VV+ V+YDFH+LPSG++NP
Sbjct: 30 VTVVLGAQWGDEGKGKVVDLLAQDADIVCRCQGGNNAGHTVVVDSVEYDFHLLPSGIINP 89
Query: 62 NCQNLIGNGVVIHVPSFFEELKS--LEAKGLKNAKGRLFISSRAHLVFDFHQRTDKLREL 119
N IGNGVVIH+P FEE + + KGL+ + RL IS RAH+VFDFHQ D ++E
Sbjct: 90 NVTAFIGNGVVIHLPGLFEEAEKNVQKGKGLEGWEKRLIISDRAHIVFDFHQAADGIQEQ 149
Query: 120 ELSGASKDXXXXXXXXXXXXPTYSTKASRSGLRVHHLVNDDPQAWEVFETRYRRLVETRQ 179
+ + P YS+KA+RSGLR+ LV+D ++ F R++ L +
Sbjct: 150 QRQ--EQAGKNLGTTKKGIGPVYSSKAARSGLRMCDLVSD----FDGFSERFKVLANQYK 203
Query: 180 QRYGSFDYDPEEELQRYKSYREQLKPFVVDSVNFMHDAIK-KNKKILVEGANALMLDIDF 238
Y + + D E ELQ+ K Y E++KP V D V F+++A+ KKILVEGANA +LDIDF
Sbjct: 204 SIYPTLEIDIEGELQKLKGYMEKIKPMVRDGVYFLYEALHGPPKKILVEGANAALLDIDF 263
Query: 239 GTYPYVTSSNXXXXXXXXXXXXPPRTIKEVFGVVKAYTTRVGEGPFPTEQLNEDGEKLQN 298
GTYP+VTSSN PP+ + EV+GVVKAYTTRVG G FPTEQ NE GE LQ
Sbjct: 264 GTYPFVTSSNCTVGGVCTGLGMPPQNVGEVYGVVKAYTTRVGIGAFPTEQDNEIGELLQT 323
Query: 299 IGAEFGVTTGRKRRCGWLDLVVLKYSNLINGYTSLNITKLDVLDTFKEIKVGVSYSVDGK 358
G EFGVTTGRKRRCGWLDLV+LKY+++ING+T+L +TKLD+LD F EIKVGV+Y +DG+
Sbjct: 324 RGREFGVTTGRKRRCGWLDLVLLKYAHMINGFTALALTKLDILDMFTEIKVGVAYKLDGE 383
Query: 359 KLESFPEDLLTLAKVEVEYVTLPGWEEDISKITNYEDLPENAQKYLKFIEDFVEVPIQWV 418
+ P + L KVEV+Y TLPGW DIS +++LP NAQ Y++FIED +++P++W+
Sbjct: 384 IIPHIPANQEVLNKVEVQYKTLPGWNTDISNARAFKELPVNAQNYVRFIEDELQIPVKWI 443
Query: 419 GTGPARDAMV 428
G G +R++M+
Sbjct: 444 GVGKSRESMI 453
>At3g57610 [F] KOG1355 Adenylosuccinate synthase
Length = 490
Score = 416 bits (1069), Expect = e-116
Identities = 216/436 (49%), Positives = 291/436 (66%), Gaps = 20/436 (4%)
Query: 2 VNVVLGSQWGDEGKGKLVDLLVGEYDIVARSAGGNNAGHTIVVN-GVKYDFHMLPSGLVN 60
V+ VLG QWGDEGKGKLVD+L +DIVAR GG NAGHTI + G K+ H++PSG++N
Sbjct: 68 VSGVLGCQWGDEGKGKLVDILAQHFDIVARCQGGANAGHTIYNSEGKKFALHLVPSGILN 127
Query: 61 PNCQNLIGNGVVIHVPSFFEELKSLEAKGLKNAKGRLFISSRAHLVFDFHQRTDKLRELE 120
+ +IGNGVV+H+P F+E+ LE+ G+ + KGR+ +S RAHL+FDFHQ D LRE E
Sbjct: 128 EDTTCVIGNGVVVHLPGLFKEIDGLESNGV-SCKGRILVSDRAHLLFDFHQEVDGLRESE 186
Query: 121 LSGASKDXXXXXXXXXXXXPTYSTKASRSGLRVHHLVNDD--PQAWEVFETRYRRLVETR 178
L+ + P YS+K R+G+RV L + D PQ ++ L+
Sbjct: 187 LAKS-----FIGTTKRGIGPAYSSKVIRNGIRVGDLRHMDTLPQKLDL-------LLSDA 234
Query: 179 QQRYGSFDYDPE---EELQRYKSYREQLKPFVVDSVNFMHDAIKKNKKILVEGANALMLD 235
R+ F Y PE EE++ YK Y ++L+P++ D+V+F++D+I + KK+LVEG A MLD
Sbjct: 235 AARFQGFKYTPEMLREEVEAYKRYADRLEPYITDTVHFINDSISQKKKVLVEGGQATMLD 294
Query: 236 IDFGTYPYVTSSNXXXXXXXXXXXXPPRTIKEVFGVVKAYTTRVGEGPFPTEQLNEDGEK 295
IDFGTYP+VTSS+ P + ++ GVVKAYTTRVG GPFPTE L G+
Sbjct: 295 IDFGTYPFVTSSSPSAGGICTGLGIAPSVVGDLIGVVKAYTTRVGSGPFPTENLGTGGDL 354
Query: 296 LQNIGAEFGVTTGRKRRCGWLDLVVLKYSNLINGYTSLNITKLDVLDTFKEIKVGVSYS- 354
L+ G EFG TTGR RRCGWLD+V LK+S ING+ SLN+TKLDVL EI++GV+Y
Sbjct: 355 LRLAGQEFGTTTGRPRRCGWLDIVALKFSCQINGFASLNLTKLDVLSDLNEIQLGVAYKR 414
Query: 355 VDGKKLESFPEDLLTLAKVEVEYVTLPGWEEDISKITNYEDLPENAQKYLKFIEDFVEVP 414
DG ++SFP DL L ++ VEY LPGW+ DIS + NY DLP+ AQ+Y++ IE+ V VP
Sbjct: 415 SDGTPVKSFPGDLRLLEELHVEYEVLPGWKSDISSVRNYSDLPKAAQQYVERIEELVGVP 474
Query: 415 IQWVGTGPARDAMVHK 430
I ++G GP RDA+++K
Sbjct: 475 IHYIGIGPGRDALIYK 490
>CE08630 [F] KOG1355 Adenylosuccinate synthase
Length = 457
Score = 414 bits (1065), Expect = e-115
Identities = 212/437 (48%), Positives = 289/437 (65%), Gaps = 18/437 (4%)
Query: 2 VNVVLGSQWGDEGKGKLVDLLVGEY--DIVARSAGGNNAGHTIVVNGVKYDFHMLPSGLV 59
V+V+LG+QWGDEGKGK++D L+ + ++ AR GGNNAGHT+V NG KYDFH+LPSG++
Sbjct: 31 VSVLLGAQWGDEGKGKIIDYLIENHKINVTARCQGGNNAGHTVVANGRKYDFHILPSGII 90
Query: 60 NPNCQNLIGNGVVIHVPSFFEELKS---LEAKGLKNAKGRLFISSRAHLVFDFHQRTDKL 116
+P C N+IGNGVV+++ +FF EL LE G + R+ ISS AHLVF H + D
Sbjct: 91 SPTCFNVIGNGVVVNLDAFFSELAHNGILEESGWEK---RIMISSEAHLVFGVHSQVDGR 147
Query: 117 RELELSGASKDXXXXXXXXXXXXPTYSTKASRSGLRVHHLVNDDPQAWEVFETRYRRLVE 176
+E L+ +K PTYS+K R+G+RV L+ D +E F +YRRLVE
Sbjct: 148 QEDSLAAKNK----IGTTNRGIGPTYSSKCFRNGIRVADLMAD----FEEFSEKYRRLVE 199
Query: 177 TRQQRYGSFDYDPEEELQRYKSYREQLKPF--VVDSVNFMHDAIKKNKKILVEGANALML 234
++++ S + + +EEL ++K +RE+L V D+V F+H+ K++LVEGAN +L
Sbjct: 200 HYKKQFPSIEVNVDEELAKFKQHREKLAELKLVGDTVGFIHEQRNAGKQVLVEGANGALL 259
Query: 235 DIDFGTYPYVTSSNXXXXXXXXXXXXPPRTIKEVFGVVKAYTTRVGEGPFPTEQLNEDGE 294
DIDFGTYPYVTSSN PP + V GVVKAY TRVG GPFPTE + DGE
Sbjct: 260 DIDFGTYPYVTSSNSTVGGACTGIGVPPTAVGNVIGVVKAYQTRVGTGPFPTELFDSDGE 319
Query: 295 KLQNIGAEFGVTTGRKRRCGWLDLVVLKYSNLINGYTSLNITKLDVLDTFKEIKVGVSYS 354
KLQ IG E GVTTGRKRRCGW+DL +L+ S +INGYT++ +TKLD+LDTF IKV V Y
Sbjct: 320 KLQTIGKEVGVTTGRKRRCGWIDLFLLRRSAMINGYTAIALTKLDILDTFPTIKVAVGYK 379
Query: 355 VDGKKLESFPEDLLTLAKVEVEYVTLPGWEEDISKITNYEDLPENAQKYLKFIEDFVEVP 414
++G+ L S P +EVEY GW E + +EDLPE ++Y+KFIEDF++VP
Sbjct: 380 LNGQVLSSPPAQANAWGAIEVEYKEFEGWNEPTVGVRKFEDLPEKCRQYVKFIEDFIKVP 439
Query: 415 IQWVGTGPARDAMVHKE 431
I ++G G R++++ ++
Sbjct: 440 IVYIGVGAERESLIVRQ 456
>Hs22049791 [F] KOG1355 Adenylosuccinate synthase
Length = 500
Score = 413 bits (1061), Expect = e-115
Identities = 203/396 (51%), Positives = 280/396 (70%), Gaps = 7/396 (1%)
Query: 34 GGNNAGHTIVVNGVKYDFHMLPSGLVNPNCQNLIGNGVVIHVPSFFEELKSLEAKGLKNA 93
GGNNAGHT+VV+G +YDFH+LPSG++N + IGNGVVIH+P FEE + E KGLK+
Sbjct: 108 GGNNAGHTVVVDGKEYDFHLLPSGIINTKAVSFIGNGVVIHLPGLFEEAEKNEKKGLKDW 167
Query: 94 KGRLFISSRAHLVFDFHQRTDKLRELELSGASKDXXXXXXXXXXXXPTYSTKASRSGLRV 153
+ RL IS RAHLVFDFHQ D L+E++ +++ PTYS+KA+R+GLR+
Sbjct: 168 EKRLIISDRAHLVFDFHQAVDGLQEVQRQ--AQEGKNIGTTKKGIGPTYSSKAARTGLRI 225
Query: 154 HHLVNDDPQAWEVFETRYRRLVETRQQRYGSFDYDPEEELQRYKSYREQLKPFVVDSVNF 213
L++D ++ F +R++ L Q + + + D E +L+R K + E+++P V D V F
Sbjct: 226 CDLLSD----FDEFSSRFKNLAHQHQSMFPTLEIDIEGQLKRLKGFAERIRPMVRDGVYF 281
Query: 214 MHDAIK-KNKKILVEGANALMLDIDFGTYPYVTSSNXXXXXXXXXXXXPPRTIKEVFGVV 272
M++A+ KKILVEGANA +LDIDFGTYP+VTSSN PP+ I +V+GVV
Sbjct: 282 MYEALHGPPKKILVEGANAALLDIDFGTYPFVTSSNCTVGGVCTGLGIPPQNIGDVYGVV 341
Query: 273 KAYTTRVGEGPFPTEQLNEDGEKLQNIGAEFGVTTGRKRRCGWLDLVVLKYSNLINGYTS 332
KAYTTRVG G FPTEQ+NE G LQ G E+GVTTGRKRRCGWLDL++L+Y++++NG+T+
Sbjct: 342 KAYTTRVGIGAFPTEQINEIGGLLQTRGHEWGVTTGRKRRCGWLDLMILRYAHMVNGFTA 401
Query: 333 LNITKLDVLDTFKEIKVGVSYSVDGKKLESFPEDLLTLAKVEVEYVTLPGWEEDISKITN 392
L +TKLD+LD E+KVGVSY ++GK++ FP + L KVEVEY TLPGW+ D +
Sbjct: 402 LALTKLDILDVLGEVKVGVSYKLNGKRIPYFPANQEMLQKVEVEYETLPGWKADTTGARR 461
Query: 393 YEDLPENAQKYLKFIEDFVEVPIQWVGTGPARDAMV 428
+EDLP AQ Y++F+E+ V V ++WVG G +R++M+
Sbjct: 462 WEDLPPQAQNYIRFVENHVGVAVKWVGVGKSRESMI 497
>Hs18587061_2 [F] KOG1355 Adenylosuccinate synthase
Length = 342
Score = 105 bits (262), Expect = 1e-22
Identities = 48/78 (61%), Positives = 62/78 (78%)
Query: 287 EQLNEDGEKLQNIGAEFGVTTGRKRRCGWLDLVVLKYSNLINGYTSLNITKLDVLDTFKE 346
+ L E GE LQ G EFGVT GRKRRCGWLDLV+LKY+++ING+T+L +TKL++LD F E
Sbjct: 199 QNLKEIGELLQTKGREFGVTIGRKRRCGWLDLVLLKYAHIINGFTALEVTKLNILDMFME 258
Query: 347 IKVGVSYSVDGKKLESFP 364
IKVGV+Y +DG+ + P
Sbjct: 259 IKVGVAYKLDGQIIPHIP 276
Score = 92.4 bits (228), Expect = 1e-18
Identities = 70/203 (34%), Positives = 97/203 (47%), Gaps = 50/203 (24%)
Query: 2 VNVVLGSQWGDEGKGKLVDLLVGEYDIVARSAGGNNAGHTIVVNGVKYDFHMLPSGLVNP 61
V VVLG QWGDEGKG++ DLL D + R GGNNAGHT+VV+ V+YDFH+LPSG++ P
Sbjct: 57 VTVVLGVQWGDEGKGEVADLLA--QDPMCRCQGGNNAGHTVVVHSVEYDFHLLPSGIIIP 114
Query: 62 NCQNLIGNGVVIHVPSFFEELKSLEAKGLKNAKGRLFISSRAHLVFDFHQRTDKLRELEL 121
N GN A G++ QR ++
Sbjct: 115 NVTAFNGNA----------------ADGVQE-----------------QQRQEQ------ 135
Query: 122 SGASKDXXXXXXXXXXXXPTYSTKASRSGLRVHHLVNDDPQAWEVFETRYRRLVETRQQR 181
A K+ P YS+KA+RSGLR+ LV+D E+F+ ++ +
Sbjct: 136 --AGKN---LGTTKKGIGPVYSSKAARSGLRMCDLVSDLVGFSEMFKVPAKQY----KSI 186
Query: 182 YGSFDYDPEEELQRYKSYREQLK 204
+ + + D E ELQ K E L+
Sbjct: 187 HPTLEIDIEGELQNLKEIGELLQ 209
Database: KOG eukaryal database 04/03
Posted date: Apr 14, 2003 1:07 PM
Number of letters in database: 30,389,216
Number of sequences in database: 60,738
Lambda K H
0.317 0.138 0.401
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 25,676,065
Number of Sequences: 60738
Number of extensions: 1096829
Number of successful extensions: 2703
Number of sequences better than 1.0e-05: 9
Number of HSP's better than 0.0 without gapping: 9
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 2664
Number of HSP's gapped (non-prelim): 11
length of query: 432
length of database: 30,389,216
effective HSP length: 109
effective length of query: 323
effective length of database: 23,768,774
effective search space: 7677314002
effective search space used: 7677314002
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.6 bits)