ORF STATUS Function Best COG Functional category Pathways and functional systems
r_klactIV4811 good R KOG0154 General function prediction only RNA-binding protein RBM5 and related proteins, contain G-patch and RRM domains
Only best alignment is shown:
BLASTP 2.2.3 [May-13-2002]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= r_klactIV4811 1647949 1650168 740
(740 letters)
Database: KOG eukaryal database 04/03
60,738 sequences; 30,389,216 total letters
Searching..................................................done
Color Key for Alignment Scores: 
Score E
Sequences producing significant alignments: (bits) Value
YNL224c [R] KOG0154 RNA-binding protein RBM5 and related protein... 467 e-131
SPBC30B4.02c [R] KOG0154 RNA-binding protein RBM5 and related pr... 88 5e-17
SPCC1442.13c [R] KOG0154 RNA-binding protein RBM5 and related pr... 54 7e-07
>YNL224c [R] KOG0154 RNA-binding protein RBM5 and related proteins contain
G-patch and RRM domains
Length = 767
Score = 467 bits (1202), Expect = e-131
Identities = 290/792 (36%), Positives = 411/792 (51%), Gaps = 84/792 (10%)
Query: 1 MAKRHKHYNARXXXXXXXXXXXPHGESRQ-----RKNHRGGTSINR-NRSELLLGGGDL- 53
MAKRH HY G RK + T N + S + LG GDL
Sbjct: 1 MAKRHSHYQGSRRRHARGSNSKKAGRGNAKGIQGRKIKKKPTPTNSWHNSSIPLGEGDLD 60
Query: 54 ------------MNPHQVEDYYFGSTAKKSSLRSGGFRPG-RLTEADELDTGRLPSRKRP 100
++P +EDYYFG AK S++ GG RPG R + +L GR RKRP
Sbjct: 61 DVGADFNPGRAFISPKTIEDYYFGRDAKSRSMKMGGLRPGNRYDSSTDLQAGRAAFRKRP 120
Query: 101 VEFIKAKELYDPSHDLILKLVKKNQHFDEPNSDGYNSSQSVSLRXXXXXXXXXXXXXXXX 160
++F+KAKE+YDPSH++I KL KN+ NS + V
Sbjct: 121 MQFVKAKEVYDPSHNMIQKLRAKNET--------KNSEEIVEREADVFEE---------- 162
Query: 161 XIPSKNTTVKIRSDNVVSENGDSESNSSAN-------------DAELFYVDMEGEEKTAD 207
P K T+ +N SEN D +S +S + D +LF+VD E ++
Sbjct: 163 --PGKMTSDVEYINNEDSENEDDDSQNSPSTDHSLSSNESKVEDGDLFFVDEEAQQSPDL 220
Query: 208 NYIKTVDVDVQERSLKLNDCTEFQPTLRVGNVELNLKDGG-SGSIEVDKPKS---SYHPF 263
IK V ++ R ++ EF P L +G VEL++ +G S I VD P +YHPF
Sbjct: 221 TKIKRVCIEEIARPREV--AIEFDPILTIGKVELSVSEGNESKEISVDVPNKGNKTYHPF 278
Query: 264 HSYIQNVMENVQXXXXXXXXXXXXXXVEQSFSISSDYEFESSEELITTGGTIEQFDSSMK 323
YI NV+ + +E + YE +S E+ + Q +S
Sbjct: 279 AGYISNVLHGMHTSDSDNDELDYE--IETENNSEPLYESSASSEVDQGFNYVGQRHNSRA 336
Query: 324 SLTIEEIPGKTITASLTTKDIS-----QGNSDN----SSGDESFGFCEDDFEGSIGKVFV 374
+ P +T + I+ +GN+DN +S + FGF E+DF + + V
Sbjct: 337 DNNLLPSPSPQLTEDIKCLSINGTKTFEGNNDNLPSPASEELEFGFKEEDFVINTNDIVV 396
Query: 375 SNIRIGAGTHSYHVSCHEIYGDSEPRWVDDEMMNE-IIAEMGLPEHRFRAYYKHLHKSFI 433
SNIR+G +SY++ C+ + GD + W+D +++ + ++ E+GLPE R AY + S I
Sbjct: 397 SNIRMGGVDNSYYLRCYRLLGDYDFHWIDQDLLTDFVVDELGLPEDRLPAYLNFIKNSLI 456
Query: 434 XXXXXXX-XYADIPFXXXXXXXXT---------ADQCEPFAXXXXXXXXXXXVSYALKYN 483
Y+DIP + D ++Y LK++
Sbjct: 457 PKIEPAEPTYSDIPISDSSDEGDSYEGDSYEDDEDMASSVVHSDIEEGLDDLIAYTLKHD 516
Query: 484 KQRKIEYHTTSLDIRGKGRNKHLIFDQTAGMDEDIKLMLQNKFATRQINKTKKRRAKEDF 543
+R + T SL+ +GKG+ K L+ D +D + LQ+KF+ R K KKR+AKEDF
Sbjct: 517 TERFKTFETKSLETKGKGKKKKLLIDDALALDTETLETLQSKFSKRIETKAKKRKAKEDF 576
Query: 544 LSQSHASSTDLLMKYPYGLHIQNIKDEFDAFYRNDRQSITFPPLDPHGNKIIGKFAYNYF 603
+ Q + +S D+L KYPYGLHIQNIKDEF++F + +TFPPLDPHGNK + K A +Y
Sbjct: 577 IDQENRNSNDMLKKYPYGLHIQNIKDEFESFLSRNNDRLTFPPLDPHGNKTVMKIAKHYN 636
Query: 604 MKASNIGKGKSTKVYVEKTKKTRFNKPAYHIISQLLRKRPVFMRIDQKAPTDTQSTFNRT 663
MK+S IGK T V VEK KKT+++ P Y +I QL+R+RPVFMRID + P + Q+ F RT
Sbjct: 637 MKSSKIGKANHTSVVVEKIKKTKWSSPNYSLIDQLMRQRPVFMRIDIRRPREEQAAFERT 696
Query: 664 VRLKVSKENFNISEGQIVGEDAPEIGIDNIGRRMLEKLGWNIGQGLGAHGNQGINEPILA 723
K + F++ EG+IVG++APEIG +NIGRRMLEKLGW G+GLG GN+GI+EPI A
Sbjct: 697 ---KTIRGKFHVKEGEIVGQNAPEIGNENIGRRMLEKLGWKSGEGLGIQGNKGISEPIFA 753
Query: 724 KVKKNKSGLRHT 735
K+KKN+SGLRH+
Sbjct: 754 KIKKNRSGLRHS 765
>SPBC30B4.02c [R] KOG0154 RNA-binding protein RBM5 and related proteins contain
G-patch and RRM domains
Length = 695
Score = 87.8 bits (216), Expect = 5e-17
Identities = 58/200 (29%), Positives = 99/200 (49%), Gaps = 3/200 (1%)
Query: 533 KTKKRRAKEDFLSQSHASSTDLLMKYPYGLHIQNIKDEFDAFYRNDRQSITFPPLDPHGN 592
K+KK+ +E S S L + + I ++ F + + I+ PP +
Sbjct: 498 KSKKKLLRESQKPSSSDSDNASLTRIDK-IFINDVYQRMQQFKHSAIEEISLPPCRKYVR 556
Query: 593 KIIGKFAYNYFMKASNIGKGKSTKVYVEKTKKTRFNKPAYHIISQLLRKRPVFMRIDQKA 652
+++ A + +K+ + G G + KT K F+ + ++S + R++ ++
Sbjct: 557 RLVHALANDLNLKSRSYGSGNKRYTMLSKTHK--FDASSVDLVSLTRIMERLQTRVEYQS 614
Query: 653 PTDTQSTFNRTVRLKVSKENFNISEGQIVGEDAPEIGIDNIGRRMLEKLGWNIGQGLGAH 712
+ + TV S + + +GQIVGEDAPEI +N GRR+LEKLGW G+GLG
Sbjct: 615 FSKSGRKSRMTVSSVRSSKATRVYDGQIVGEDAPEISKENPGRRLLEKLGWYAGKGLGHP 674
Query: 713 GNQGINEPILAKVKKNKSGL 732
N+G + + A VK ++SGL
Sbjct: 675 ENEGSKDSLRAIVKVSRSGL 694
>SPCC1442.13c [R] KOG0154 RNA-binding protein RBM5 and related proteins contain
G-patch and RRM domains
Length = 187
Score = 54.3 bits (129), Expect = 7e-07
Identities = 26/56 (46%), Positives = 40/56 (71%), Gaps = 2/56 (3%)
Query: 677 EGQIVGEDAPEIGIDNIGRRMLEKLGWNIGQGLGAHGNQGINEPILAKVKKNKSGL 732
+G +VG AP I + G+++LE +GW+ G+GLG+ NQG+ +P++A VK NK GL
Sbjct: 133 DGHVVGSSAPAIN-NGKGKQLLEMMGWSRGKGLGSE-NQGMVDPVVAVVKNNKQGL 186
Database: KOG eukaryal database 04/03
Posted date: Apr 14, 2003 1:07 PM
Number of letters in database: 30,389,216
Number of sequences in database: 60,738
Lambda K H
0.314 0.133 0.377
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 41,385,164
Number of Sequences: 60738
Number of extensions: 1759339
Number of successful extensions: 3589
Number of sequences better than 1.0e-05: 3
Number of HSP's better than 0.0 without gapping: 2
Number of HSP's successfully gapped in prelim test: 1
Number of HSP's that attempted gapping in prelim test: 3574
Number of HSP's gapped (non-prelim): 5
length of query: 740
length of database: 30,389,216
effective HSP length: 114
effective length of query: 626
effective length of database: 23,465,084
effective search space: 14689142584
effective search space used: 14689142584
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.9 bits)