ORF STATUS Function Best COG Functional category Pathways and functional systems
r_klactIV4927 check: MH Q KOG0024 Secondary metabolites biosynthesis, transport and catabolism Sorbitol dehydrogenase
Only best alignment is shown:
BLASTP 2.2.3 [May-13-2002]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= r_klactIV4927 1694826 1695983 386
(386 letters)
Database: KOG eukaryal database 04/03
60,738 sequences; 30,389,216 total letters
Searching..................................................done
Color Key for Alignment Scores: 
Score E
Sequences producing significant alignments: (bits) Value
SPBC1198.01 [Q] KOG0024 Sorbitol dehydrogenase 160 3e-39
At5g63620 [Q] KOG0022 Alcohol dehydrogenase class III 135 1e-31
7298873 [Q] KOG0024 Sorbitol dehydrogenase 118 2e-26
CE06215 [Q] KOG0024 Sorbitol dehydrogenase 117 3e-26
7299382 [Q] KOG0024 Sorbitol dehydrogenase 117 3e-26
YDL168w [Q] KOG0022 Alcohol dehydrogenase class III 115 1e-25
Hs11496891 [Q] KOG0022 Alcohol dehydrogenase class III 110 5e-24
At5g51970 [Q] KOG0024 Sorbitol dehydrogenase 107 3e-23
YDL246c [Q] KOG0024 Sorbitol dehydrogenase 107 4e-23
YJR159w [Q] KOG0024 Sorbitol dehydrogenase 106 5e-23
CE06216 [Q] KOG0024 Sorbitol dehydrogenase 105 9e-23
YAL060w [Q] KOG0024 Sorbitol dehydrogenase 99 8e-21
7299380 [Q] KOG0022 Alcohol dehydrogenase class III 98 2e-20
SPBC1539.07c [Q] KOG0022 Alcohol dehydrogenase class III 96 7e-20
At5g43940 [Q] KOG0022 Alcohol dehydrogenase class III 96 7e-20
Hs20537182 [Q] KOG0022 Alcohol dehydrogenase class III 96 9e-20
Hs4501929 [Q] KOG0022 Alcohol dehydrogenase class III 96 1e-19
At1g22430 [Q] KOG0022 Alcohol dehydrogenase class III 95 2e-19
At1g77120 [Q] KOG0022 Alcohol dehydrogenase class III 95 2e-19
YAL061w [Q] KOG0024 Sorbitol dehydrogenase 94 3e-19
Hs4501931 [Q] KOG0022 Alcohol dehydrogenase class III 94 3e-19
At1g64710 [Q] KOG0022 Alcohol dehydrogenase class III 94 3e-19
Hs4507155 [Q] KOG0024 Sorbitol dehydrogenase 94 4e-19
Hs4501939 [Q] KOG0022 Alcohol dehydrogenase class III 93 6e-19
CE22292_2 [Q] KOG0022 Alcohol dehydrogenase class III 93 6e-19
Hs4501933 [Q] KOG0022 Alcohol dehydrogenase class III 92 1e-18
At5g42250 [Q] KOG0022 Alcohol dehydrogenase class III 91 2e-18
At1g22440 [Q] KOG0022 Alcohol dehydrogenase class III 90 6e-18
CE23822 [Q] KOG0022 Alcohol dehydrogenase class III 89 1e-17
Hs4501935 [Q] KOG0022 Alcohol dehydrogenase class III 88 2e-17
SPBC1773.06c [CR] KOG1198 Zinc-binding oxidoreductase 88 2e-17
YLR070c [Q] KOG0024 Sorbitol dehydrogenase 87 4e-17
Hs4501941 [Q] KOG0022 Alcohol dehydrogenase class III 87 4e-17
At1g32780 [Q] KOG0022 Alcohol dehydrogenase class III 84 3e-16
SPCC13B11.04c [Q] KOG0022 Alcohol dehydrogenase class III 82 1e-15
At4g22110 [Q] KOG0022 Alcohol dehydrogenase class III 81 3e-15
YBR046c [CR] KOG1197 Predicted quinone oxidoreductase 79 1e-14
SPBC1773.05c [Q] KOG0024 Sorbitol dehydrogenase 79 1e-14
SPCC13B11.01 [Q] KOG0023 Alcohol dehydrogenase class V 78 2e-14
7300579 [Q] KOG0024 Sorbitol dehydrogenase 72 2e-12
CE12212 [Q] KOG0023 Alcohol dehydrogenase class V 69 2e-11
CE12214 [Q] KOG0023 Alcohol dehydrogenase class V 68 2e-11
CE20628 [Q] KOG0023 Alcohol dehydrogenase class V 68 3e-11
YMR303c [Q] KOG0023 Alcohol dehydrogenase class V 67 6e-11
YBR145w [Q] KOG0023 Alcohol dehydrogenase class V 67 6e-11
At4g37990 [Q] KOG0023 Alcohol dehydrogenase class V 66 8e-11
At4g34230 [Q] KOG0023 Alcohol dehydrogenase class V 66 8e-11
Hs20549232 [Q] KOG0024 Sorbitol dehydrogenase 66 1e-10
YMR083w [Q] KOG0023 Alcohol dehydrogenase class V 65 1e-10
Hs22052673 [Q] KOG0022 Alcohol dehydrogenase class III 64 3e-10
Hs18583841 [Q] KOG0024 Sorbitol dehydrogenase 64 5e-10
At4g37970 [Q] KOG0023 Alcohol dehydrogenase class V 64 5e-10
YOL086c [Q] KOG0023 Alcohol dehydrogenase class V 62 1e-09
YCR105w [Q] KOG0023 Alcohol dehydrogenase class V 62 1e-09
At3g56460 [CR] KOG1198 Zinc-binding oxidoreductase 62 1e-09
Hs4758912 [CR] KOG1198 Zinc-binding oxidoreductase 60 4e-09
Hs13236495 [CR] KOG1198 Zinc-binding oxidoreductase 60 4e-09
At3g19450 [Q] KOG0023 Alcohol dehydrogenase class V 59 9e-09
At1g72680 [Q] KOG0023 Alcohol dehydrogenase class V 59 9e-09
At4g21580 [CR] KOG1198 Zinc-binding oxidoreductase 59 1e-08
At4g39330 [Q] KOG0023 Alcohol dehydrogenase class V 58 3e-08
At4g37980 [Q] KOG0023 Alcohol dehydrogenase class V 56 1e-07
At2g21730 [Q] KOG0023 Alcohol dehydrogenase class V 55 1e-07
YMR318c [Q] KOG0023 Alcohol dehydrogenase class V 55 2e-07
At2g21890 [Q] KOG0023 Alcohol dehydrogenase class V 55 2e-07
At5g61510 [CR] KOG1197 Predicted quinone oxidoreductase 52 2e-06
Hs22044912 [Q] KOG0022 Alcohol dehydrogenase class III 50 6e-06
>SPBC1198.01 [Q] KOG0024 Sorbitol dehydrogenase
Length = 423
Score = 160 bits (405), Expect = 3e-39
Identities = 118/381 (30%), Positives = 185/381 (47%), Gaps = 54/381 (14%)
Query: 31 MKAMVYYGANDIKFEDREQPQILSSTDAIIKMTHTSIC-GTDLGIWKGKNPEIEQTAQTK 89
MKA V+ G ++K + +P I D I+K T +IC G+D I+ G+ P IE+
Sbjct: 37 MKACVWDGPLNVKIAEVPKPTITHPKDVIVKTTACTICSGSDSHIFSGEMPGIEK----- 91
Query: 90 EGSFNGRILGHEGIGIIDEVGDAVHNFKKGDRVIVSCISRCGTCENCAKSLYSHC--TNG 147
G ILGHE GI+ E GD V+N + GDRV+++ CG C C + Y+ C TN
Sbjct: 92 -----GAILGHESCGIVAEKGDEVNNLEIGDRVVIAFDLACGQCSFCKRHEYAACDTTND 146
Query: 148 G-----------GWILGYM-----IDGTQAEYVRTPFADTSLYSVPENLSDEAAVMLSDA 191
I GY + G QAEY+R PFA+ + +P+++ D + +SD
Sbjct: 147 SKLMDVNYGSHHSAIFGYTKLLGDVPGCQAEYIRVPFAEINCCKLPDDIPDSEGLFMSDV 206
Query: 192 LPTAHEIGVQMGNVKPGDTVAIVGAGPVGMGCVLTSQLYSPSLLIVVDIDDNRLAMAKE- 250
L T+ +G VK GDTVAI G GP+G+ +Q+ S +I +++ R+ +A++
Sbjct: 207 LCTSLH-ACTLGEVKKGDTVAIWGMGPIGLYAGRWAQILGASKVIGIEVVPERIELARQK 265
Query: 251 MGSTHTINSAKEDAVSKILEYTNGRGVDCVMEAVGAQATWDI------------------ 292
G T + D KI+E + GVDC +EA G + + I
Sbjct: 266 FGFTVIDRNEVSDVPKKIMELVS-NGVDCAIEASGFRFSTSILHKVERAVGLETDSPDMI 324
Query: 293 --CQRVIKEGGHLANVGVH-GKPVNFEIDKLWIKNLTITSGLVN-TNTTGMLMKSCCSGK 348
C +++ GH++ + + G F I + +K+LTI SG N G ++ + SGK
Sbjct: 325 TECLNAVRKYGHVSIIADYVGTSNQFPIGHVVMKHLTIRSGQCPCQNYFGYVIDNIRSGK 384
Query: 349 LKSERLVTHHCNFGEMSGNYN 369
+ +VT+ F ++ YN
Sbjct: 385 IDPRWMVTNKIKFDDLPDAYN 405
>At5g63620 [Q] KOG0022 Alcohol dehydrogenase class III
Length = 383
Score = 135 bits (339), Expect = 1e-31
Identities = 87/288 (30%), Positives = 139/288 (48%), Gaps = 35/288 (12%)
Query: 55 STDAIIKMTHTSICGTDLGIWKGKNPEIEQTAQTKEGSFNGRILGHEGIGIIDEVGDA-- 112
S + +IK +C +DL + KG+ P ++GHE G + E G
Sbjct: 36 SNEILIKTKACGVCHSDLHVMKGEIPFASPC-----------VIGHEITGEVVEHGPLTD 84
Query: 113 ---VHNFKKGDRVIVSCISRCGTCENCAKSLYSHCTNGGGW--ILGYMIDGTQAEYVRTP 167
++ F G RV+ + I CGTC CAK C + + G + DG ++R
Sbjct: 85 HKIINRFPIGSRVVGAFIMPCGTCSYCAKGHDDLCEDFFAYNRAKGTLYDGETRLFLRHD 144
Query: 168 FADTSLYSV-----------------PENLSDEAAVMLSDALPTAHEIGVQMGNVKPGDT 210
+ +YS+ PE+L + +L A+ TA+ ++PGD+
Sbjct: 145 DSPVYMYSMGGMAEYCVTPAHGLAPLPESLPYSESAILGCAVFTAYGAMAHAAEIRPGDS 204
Query: 211 VAIVGAGPVGMGCVLTSQLYSPSLLIVVDIDDNRLAMAKEMGSTHTINSAKEDAVSKILE 270
+A++G G VG C+ ++ + S +I VD+ D++L AK +G+TH +N+AKEDAV +I E
Sbjct: 205 IAVIGIGGVGSSCLQIARAFGASDIIAVDVQDDKLQKAKTLGATHIVNAAKEDAVERIRE 264
Query: 271 YTNGRGVDCVMEAVGAQATWDICQRVIKEGGHLANVGVHGKPVNFEID 318
T G GVD +EA+G T+ C +K+GG +G+ EID
Sbjct: 265 ITGGMGVDVAVEALGKPQTFMQCTLSVKDGGKAVMIGLSQAGSVGEID 312
>7298873 [Q] KOG0024 Sorbitol dehydrogenase
Length = 360
Score = 118 bits (295), Expect = 2e-26
Identities = 87/337 (25%), Positives = 154/337 (44%), Gaps = 26/337 (7%)
Query: 35 VYYGANDIKFEDREQPQILSSTDAIIKMTHTSICGTDLGIWKGKNPEIEQTAQTKEGSF- 93
V +G D++ E R P+I + + ++ M ICG+D + A + G F
Sbjct: 9 VLHGIEDMRLEQRPIPEI-ADDEVLLAMDSVGICGSD----------VHYLAHGRIGDFV 57
Query: 94 --NGRILGHEGIGIIDEVGDAVHNFKKGDRVIVSCISRCGTCENCAKSLYSHCTNGGGWI 151
I+GHE G++ ++G V K GDRV + C C++C + Y+ C G +
Sbjct: 58 LTKPMIIGHESAGVVAKLGKKVTTLKVGDRVAIEPGVPCRKCDHCKQGKYNLCP-GMVFC 116
Query: 152 LGYMIDGTQAEYVRTPFADTSLYSVPENLSDEAAVMLSDALPTAHEIGVQMGNVKPGDTV 211
DG Y + A + +P++++ E +L H + V G V
Sbjct: 117 ATPPYDGNLTRYYK--HAADFCFKLPDHVTMEEGALLEPLSVGVH--ACKRAEVTLGSKV 172
Query: 212 AIVGAGPVGMGCVLTSQLYSPSLLIVVDIDDNRLAMAKEMGSTHTI-----NSAKEDAVS 266
I+GAGP+G+ ++ +Q S +++ D+ RL +AKE+G+THT+ +A+E AV
Sbjct: 173 LILGAGPIGLVTLMAAQAMGASEILITDLVQQRLDVAKELGATHTLLLKRDQTAEETAV- 231
Query: 267 KILEYTNGRGVDCVMEAVGAQATWDICQRVIKEGGHLANVGVHGKPVNFEIDKLWIKNLT 326
+++ T G D ++ GA+++ + + GG + VG+ + + + +
Sbjct: 232 -LVQKTMGGQPDKSIDCCGAESSARLAIFATRSGGIVVVVGMGAAEIKLPLINALAREVD 290
Query: 327 ITSGLVNTNTTGMLMKSCCSGKLKSERLVTHHCNFGE 363
I N + SGK+ +RLVTHH + E
Sbjct: 291 IRGVFRYCNDYAAALALVASGKVNVKRLVTHHFDIKE 327
>CE06215 [Q] KOG0024 Sorbitol dehydrogenase
Length = 347
Score = 117 bits (293), Expect = 3e-26
Identities = 96/355 (27%), Positives = 159/355 (44%), Gaps = 23/355 (6%)
Query: 35 VYYGANDIKFEDREQPQILSSTDAIIKMTHTSICGTDLGIWK--GKNPEIEQTAQTKEGS 92
V YG +D++ E P+ ++K+ ICG+D+ W P + +
Sbjct: 9 VLYGVDDLRLEQVPIPKP-GPNQVLVKVHTVGICGSDVHYWTHGAIGPFVVKEPM----- 62
Query: 93 FNGRILGHEGIGIIDEVGDAVHNFKKGDRVIVSCISRCGTCENCAKSLYSHCTNGGGWIL 152
I+GHE GI+ EVG+ V + K GDR+ + C CE+C Y+ C +
Sbjct: 63 ----IVGHETSGIVSEVGNEVKHLKVGDRIAMEPGLPCKLCEHCKTGRYNLCPEMR-FFA 117
Query: 153 GYMIDGTQAEYVRTPFADTSLYSVPENLSDEAAVMLSDALPTAHEIGVQMGNVKPGDTVA 212
+ GT + +V AD + +P+NLS E ++ H + GNV+ G V
Sbjct: 118 TPPVHGTLSRFV-VHDADFC-FKLPDNLSFEDGALIEPLSVAIH--ACRRGNVQMGHRVL 173
Query: 213 IVGAGPVGMGCVLTSQLYSPSLLIVVDIDDNRLAMAKEMGSTHTIN--SAKEDAV-SKIL 269
++GAGP+G+ ++T++ +++ D+DD RLA+AK++G+ TIN DAV S+I+
Sbjct: 174 VLGAGPIGVLNLITAKAVGAGKVVITDLDDGRLALAKKLGADATINVKGKSLDAVKSEII 233
Query: 270 EYTNGRGVDCVMEAVGAQATWDICQRVIKEGGHLANVGVHGKPVNFEIDKLWIKNLTITS 329
+ D +E GAQ + + K GG + VG+ V I + + + +
Sbjct: 234 TALGDQQPDVCIECTGAQPSIETAITTTKSGGVIVLVGLGADRVEIPIIESATREVDMRG 293
Query: 330 GLVNTNTTGMLMKSCCSGKLKSERLVTHHCNFGEMSGNYNIFKHAAEEKAMKLLI 384
N ++ SGKL L H E FK + +K+ I
Sbjct: 294 IFRYVNCYPTAIELISSGKLNLSGLTRAHYKLEE---TQEAFKRTQKADVIKVFI 345
>7299382 [Q] KOG0024 Sorbitol dehydrogenase
Length = 360
Score = 117 bits (293), Expect = 3e-26
Identities = 87/336 (25%), Positives = 152/336 (44%), Gaps = 24/336 (7%)
Query: 35 VYYGANDIKFEDREQPQILSSTDAIIKMTHTSICGTDLGIWKGKNPEIEQTAQTKEGSF- 93
V +G D++ E R P+I + + ++ M ICG+D + A + G F
Sbjct: 9 VLHGIEDLRLEQRPIPEI-ADDEVLLAMDSVGICGSD----------VHYLAHGRIGDFV 57
Query: 94 --NGRILGHEGIGIIDEVGDAVHNFKKGDRVIVSCISRCGTCENCAKSLYSHCTNGGGWI 151
I+GHE G++ ++G V K GDRV + C C++C + Y+ C + +
Sbjct: 58 LTKPMIIGHEAAGVVAKLGKKVTTLKVGDRVAIEPGVPCRYCDHCKQGRYNLCADMV-FC 116
Query: 152 LGYMIDGTQAEYVRTPFADTSLYSVPENLSDEAAVMLSDALPTAHEIGVQMGNVKPGDTV 211
DG Y + A + +P+++S E +L H + V G V
Sbjct: 117 ATPPYDGNLTRYYK--HAADFCFKLPDHVSMEEGALLEPLSVGVH--ACRRAGVGLGSKV 172
Query: 212 AIVGAGPVGMGCVLTSQLYSPSLLIVVDIDDNRLAMAKEMGSTHTI----NSAKEDAVSK 267
I+GAGP+G+ +L +Q S +++ D+ RL +AKE+G+THT+ + + E+ V K
Sbjct: 173 LILGAGPIGLVTLLAAQAMGASEILITDLVQQRLDVAKELGATHTLLLQRDQSAEETV-K 231
Query: 268 ILEYTNGRGVDCVMEAVGAQATWDICQRVIKEGGHLANVGVHGKPVNFEIDKLWIKNLTI 327
++ T D ++ GA+++ + + GG + VG+ V + + + I
Sbjct: 232 VVHQTMSEVPDKSIDCCGAESSARLAIFATRSGGVVVVVGMGAPEVKLPLINALAREIDI 291
Query: 328 TSGLVNTNTTGMLMKSCCSGKLKSERLVTHHCNFGE 363
N + SGK+ +RLVTHH + E
Sbjct: 292 RGVFRYCNDYSAALALVASGKVNVKRLVTHHYDITE 327
>YDL168w [Q] KOG0022 Alcohol dehydrogenase class III
Length = 386
Score = 115 bits (288), Expect = 1e-25
Identities = 97/340 (28%), Positives = 150/340 (43%), Gaps = 50/340 (14%)
Query: 60 IKMTHTSICGTDLGIWKGKNPEIEQTAQTKEGSFNGRILGHEGIGIIDEVGDAVHNFKKG 119
IK+ +T++C TD G +PE G F +LGHEG GI++ VGD V K G
Sbjct: 41 IKIEYTAVCHTDAYTLSGSDPE---------GLFPC-VLGHEGAGIVESVGDDVITVKPG 90
Query: 120 DRVIVSCISRCGTCENCAKSLYSHC-----TNGGGW---------------ILGYMIDGT 159
D VI + CG C+ C + C T G G I +M T
Sbjct: 91 DHVIALYTAECGKCKFCTSGKTNLCGAVRATQGKGVMPDGTTRFHNAKGEDIYHFMGCST 150
Query: 160 QAEYVRTPFADTSLYSVPENLSDEAAVMLSDALPTAHEIGVQMGNVKPGDTVAIVGAGPV 219
+EY T AD S+ ++ +AA +L + T ++ NV+ GDTVA+ G G V
Sbjct: 151 FSEY--TVVADVSVVAIDPKAPLDAACLLGCGVTTGFGAALKTANVQKGDTVAVFGCGTV 208
Query: 220 GMGCVLTSQLYSPSLLIVVDIDDNRLAMAKEMGSTHTINSAKED------AVSKILEYTN 273
G+ + ++L S +I +DI++ + + G+T +N KED V K++E T+
Sbjct: 209 GLSVIQGAKLRGASKIIAIDINNKKKQYCSQFGATDFVN-PKEDLAKDQTIVEKLIEMTD 267
Query: 274 GRGVDCVMEAVG-AQATWDICQRVIKEGGHLANVGVHG-------KPVNFEIDKLWIKNL 325
G G+D + G + D + K G +GV +P ++W
Sbjct: 268 G-GLDFTFDCTGNTKIMRDALEACHKGWGQSIIIGVAAAGEEISTRPFQLVTGRVW--KG 324
Query: 326 TITSGLVNTNTTGMLMKSCCSGKLKSERLVTHHCNFGEMS 365
+ G+ + G L+K G LK E +TH F E++
Sbjct: 325 SAFGGIKGRSEMGGLIKDYQKGALKVEEFITHRRPFKEIN 364
>Hs11496891 [Q] KOG0022 Alcohol dehydrogenase class III
Length = 374
Score = 110 bits (274), Expect = 5e-24
Identities = 93/340 (27%), Positives = 146/340 (42%), Gaps = 44/340 (12%)
Query: 60 IKMTHTSICGTDLGIWKGKNPEIEQTAQTKEGSFNGRILGHEGIGIIDEVGDAVHNFKKG 119
IK+ T++C TD G +PE G F ILGHEG GI++ VG+ V K G
Sbjct: 37 IKIIATAVCHTDAYTLSGADPE---------GCFPV-ILGHEGAGIVESVGEGVTKLKAG 86
Query: 120 DRVIVSCISRCGTCENCAKSLYSHC-------------------TNGGGWILGYMIDGTQ 160
D VI I +CG C+ C + C T G IL YM T
Sbjct: 87 DTVIPLYIPQCGECKFCLNPKTNLCQKIRVTQGKGLMPDGTSRFTCKGKTILHYMGTSTF 146
Query: 161 AEYVRTPFADTSLYSVPENLSDEAAVMLSDALPTAHEIGVQMGNVKPGDTVAIVGAGPVG 220
+EY T AD S+ + +L + T + V ++PG A+ G G VG
Sbjct: 147 SEY--TVVADISVAKIDPLAPLYKVCLLGCGISTGYGAAVNTAKLEPGSVCAVFGLGGVG 204
Query: 221 MGCVLTSQLYSPSLLIVVDIDDNRLAMAKEMGSTHTIN--SAKEDAVSKILEYTNGRGVD 278
+ ++ ++ S +I VDI+ ++ A AKE G+T IN + ++E T+G GVD
Sbjct: 205 LAVIMGCKVAGASRIIGVDINKDKFARAKEFGATECINPQDLSKPIQEVLIEMTDG-GVD 263
Query: 279 CVMEAVG----AQATWDICQR----VIKEGGHLANVGVHGKPVNFEIDKLWIKNLTITSG 330
E +G +A + C + + G + + +P + W T G
Sbjct: 264 YSFECIGNVKVMRAALEACHKGWGVSVVVGVAASGEEIATRPFQLVTGRTW--KGTAFGG 321
Query: 331 LVNTNTTGMLMKSCCSGKLKSERLVTHHCNFGEMSGNYNI 370
+ + L+ S K+K + VTH+ +F E++ + +
Sbjct: 322 WKSVESVPKLVSEYMSKKIKVDEFVTHNLSFDEINKAFEL 361
>At5g51970 [Q] KOG0024 Sorbitol dehydrogenase
Length = 364
Score = 107 bits (267), Expect = 3e-23
Identities = 86/333 (25%), Positives = 148/333 (43%), Gaps = 23/333 (6%)
Query: 38 GANDIKFEDREQPQILSST---DAIIKMTHTSICGTDLGIWKGKNPEIEQTAQTKEGSFN 94
G N +K QP +L S D ++M ICG+D+ K +
Sbjct: 25 GINTLKI----QPFLLPSVGPHDVRVRMKAVGICGSDVHYLKTMRCADFVVKEPM----- 75
Query: 95 GRILGHEGIGIIDEVGDAVHNFKKGDRVIVSCISRCGTCENCAKSLYSHCTNGGGWILGY 154
++GHE GII+EVG+ V + GDRV + C C C + Y+ C +
Sbjct: 76 --VIGHECAGIIEEVGEEVKHLVVGDRVALEPGISCWRCNLCREGRYNLCPEMK-FFATP 132
Query: 155 MIDGTQAEYVRTPFADTSLYSVPENLSDEAAVMLSDALPTAHEIGVQMGNVKPGDTVAIV 214
+ G+ A V P AD + +PEN+S E M H + V P V ++
Sbjct: 133 PVHGSLANQVVHP-ADLC-FKLPENVSLEEGAMCEPLSVGVH--ACRRAEVGPETNVLVM 188
Query: 215 GAGPVGMGCVLTSQLYSPSLLIVVDIDDNRLAMAKEMGSTH--TINSAKEDAVSKI--LE 270
GAGP+G+ +L ++ +S +++VD+D+NRLA+AK++G+ + + ED S++ ++
Sbjct: 189 GAGPIGLVTMLAARAFSVPRIVIVDVDENRLAVAKQLGADEIVQVTTNLEDVGSEVEQIQ 248
Query: 271 YTNGRGVDCVMEAVGAQATWDICQRVIKEGGHLANVGVHGKPVNFEIDKLWIKNLTITSG 330
G +D + G T + GG + VG+ + + + + +
Sbjct: 249 KAMGSNIDVTFDCAGFNKTMSTALAATRCGGKVCLVGMGHGIMTVPLTPAAAREVDVVGV 308
Query: 331 LVNTNTTGMLMKSCCSGKLKSERLVTHHCNFGE 363
NT + ++ SGK+ + L+TH F +
Sbjct: 309 FRYKNTWPLCLEFLTSGKIDVKPLITHRFGFSQ 341
>YDL246c [Q] KOG0024 Sorbitol dehydrogenase
Length = 357
Score = 107 bits (266), Expect = 4e-23
Identities = 98/358 (27%), Positives = 153/358 (42%), Gaps = 39/358 (10%)
Query: 29 NIMKAMVYYGANDIKFEDREQPQILSSTDAIIKMTHTSICGTDLGIWK--GKNPEIEQTA 86
N A+V DI E R P I + + T ICG+D+ ++ G I +
Sbjct: 4 NSNPAVVLEKVGDIAIEQRPIPTIKDPHYVKLAIKATGICGSDIHYYRSGGIGKYILKAP 63
Query: 87 QTKEGSFNGRILGHEGIGIIDEVGDAVHNFKKGDRVIVSCISRCGTCENCAKSLYSHCTN 146
+LGHE G + EVGDAV K GDRV + E S YS T
Sbjct: 64 M---------VLGHESSGQVVEVGDAVTRVKVGDRVAI---------EPGVPSRYSDETK 105
Query: 147 GGGWIL-GYM-------IDGTQAEYVRTPFADTSLYSVPENLSDEAAVMLSDALPTAHEI 198
G + L +M IDGT +Y +P + L +PE +S E + H
Sbjct: 106 EGSYNLCPHMAFAATPPIDGTLVKYYLSP--EDFLVKLPEGVSYEEGACVEPLSVGVHSN 163
Query: 199 GVQMGNVKPGDTVAIVGAGPVGMGCVLTSQLYSPSLLIVVDIDDNRLAMAKEMGSTHTIN 258
++ V+ G V + GAGPVG+ ++ + + +I VD+ DN+L AK+ G+T+T N
Sbjct: 164 --KLAGVRFGTKVVVFGAGPVGLLTGAVARAFGATDVIFVDVFDNKLQRAKDFGATNTFN 221
Query: 259 SAK------EDAVSKILEYTNGRGVDCVMEAVGAQATWDICQRVIKEGGHLANVGVHGKP 312
S++ +D + + G D V E GA D + K GG + VG+
Sbjct: 222 SSQFSTDKAQDLADGVQKLLGGNHADVVFECSGADVCIDAAVKTTKVGGTMVQVGMGKNY 281
Query: 313 VNFEIDKLWIKNLTITSGL-VNTNTTGMLMKSCCSGKLKSERLVTHHCNFGEMSGNYN 369
NF I ++ K + + + + +GK+ + L+TH F + + Y+
Sbjct: 282 TNFPIAEVSGKEMKLIGCFRYSFGDYRDAVNLVATGKVNVKPLITHKFKFEDAAKAYD 339
>YJR159w [Q] KOG0024 Sorbitol dehydrogenase
Length = 357
Score = 106 bits (265), Expect = 5e-23
Identities = 92/350 (26%), Positives = 150/350 (42%), Gaps = 23/350 (6%)
Query: 29 NIMKAMVYYGANDIKFEDREQPQILSSTDAIIKMTHTSICGTDLGIWK--GKNPEIEQTA 86
N A+V DI E R P I + + T ICG+D+ ++ G I +
Sbjct: 4 NSNPAVVLEKVGDIAIEQRPIPTIKDPHYVKLAIKATGICGSDIHYYRSGGIGKYILKAP 63
Query: 87 QTKEGSFNGRILGHEGIGIIDEVGDAVHNFKKGDRVIVSCISRCGTCENCAKSLYSHCTN 146
+LGHE G + EVGDAV K GDRV + + + Y+ C +
Sbjct: 64 M---------VLGHESSGQVVEVGDAVTRVKVGDRVAIEPGVPSRYSDETKEGRYNLCPH 114
Query: 147 GGGWILGYMIDGTQAEYVRTPFADTSLYSVPENLSDEAAVMLSDALPTAHEIGVQMGNVK 206
+ IDGT +Y +P + L +PE +S E + H ++ V+
Sbjct: 115 MA-FAATPPIDGTLVKYYLSP--EDFLVKLPEGVSYEEGACVEPLSVGVHSN--KLAGVR 169
Query: 207 PGDTVAIVGAGPVGMGCVLTSQLYSPSLLIVVDIDDNRLAMAKEMGSTHTINSAK----- 261
G V + GAGPVG+ ++ + + +I VD+ DN+L AK+ G+T+T NS++
Sbjct: 170 FGTKVVVFGAGPVGLLTGAVARAFGATDVIFVDVFDNKLQRAKDFGATNTFNSSQFSTDK 229
Query: 262 -EDAVSKILEYTNGRGVDCVMEAVGAQATWDICQRVIKEGGHLANVGVHGKPVNFEIDKL 320
+D + + G D V E GA D + K GG + VG+ NF I ++
Sbjct: 230 AQDLADGVQKLLGGNHADVVFECSGADVCIDAAVKTTKVGGTMVQVGMGKNYTNFPIAEV 289
Query: 321 WIKNLTITSGL-VNTNTTGMLMKSCCSGKLKSERLVTHHCNFGEMSGNYN 369
K + + + + +GK+ + L+TH F + + Y+
Sbjct: 290 SGKEMKLIGCFRYSFGDYRDAVNLVATGKVNVKPLITHKFKFEDAAKAYD 339
>CE06216 [Q] KOG0024 Sorbitol dehydrogenase
Length = 347
Score = 105 bits (263), Expect = 9e-23
Identities = 88/356 (24%), Positives = 158/356 (43%), Gaps = 25/356 (7%)
Query: 35 VYYGANDIKFEDREQPQILSSTDAIIKMTHTSICGTDLGIWKGKNPEIEQTAQTKEGSF- 93
V YG ND++ E + ++K+ ICG+D + GSF
Sbjct: 9 VLYGINDLRLEQAPISKP-GPRQVLVKINTVGICGSD----------VHFLTHGAIGSFV 57
Query: 94 --NGRILGHEGIGIIDEVGDAVHNFKKGDRVIVSCISRCGTCENCAKSLYSHCTNGGGWI 151
+LGHE G++ E+G V FK GDR+ + C CE+C Y+ C + +
Sbjct: 58 VKEPMVLGHESSGVVSEIGSEVKGFKVGDRIAMEPGLPCKLCEHCKIGRYNLCPDMR-FF 116
Query: 152 LGYMIDGTQAEYVRTPFADTSLYSVPENLSDEAAVMLSDALPTAHEIGVQMGNVKPGDTV 211
++G + +V AD + +P+NLS E +L + L A + + G V+ G +
Sbjct: 117 ATPPVNGALSRFV-VHDADFC-FKLPDNLSFEDGALL-EPLSVAIQ-ACRRGTVQMGQKI 172
Query: 212 AIVGAGPVGMGCVLTSQLYSPSLLIVVDIDDNRLAMAKEMGSTHTIN---SAKEDAVSKI 268
++GAGP+G+ +LT++ S +++ D++D RLA+A+ +G+ TIN ++ S+I
Sbjct: 173 LVLGAGPIGVLNLLTAKAIGASKVVITDLNDERLALARLLGADATINVMGKRSDEVRSEI 232
Query: 269 LEYTNGRGVDCVMEAVGAQATWDICQRVIKEGGHLANVGVHGKPVNFEIDKLWIKNLTIT 328
++ + +E G Q + + GG + VG+ + V + + + + +
Sbjct: 233 IKAFGDQQPHVSIECTGVQPCVETAIMTTRSGGVVVLVGLGAERVEIPLIQSPTREVDLR 292
Query: 329 SGLVNTNTTGMLMKSCCSGKLKSERLVTHHCNFGEMSGNYNIFKHAAEEKAMKLLI 384
+ N ++ SGKL L H E + FK +K+ I
Sbjct: 293 GTFRSANCYSTAIELISSGKLDLSGLTRAHYKLEE---SLEAFKRTQNGDVIKVFI 345
>YAL060w [Q] KOG0024 Sorbitol dehydrogenase
Length = 382
Score = 99.4 bits (246), Expect = 8e-21
Identities = 87/328 (26%), Positives = 147/328 (44%), Gaps = 39/328 (11%)
Query: 31 MKAMVYYGANDIKF-EDREQPQILSSTDAIIKMTHTSICGTDLG------IWKGKNPEIE 83
M+A+ Y+ DI F D +P+I + + II ++ ICG+DL I+ K+ E
Sbjct: 1 MRALAYFKKGDIHFTNDIPRPEIQTDDEVIIDVSWCGICGSDLHEYLDGPIFMPKDGECH 60
Query: 84 QTAQTKEGSFNGRILGHEGIGIIDEVGDAVHNFKKGDRVIVSCISRCGT----------- 132
+ + +GHE GI+ +VG V K GD V+V S C
Sbjct: 61 KLSNAALPL----AMGHEMSGIVSKVGPKVTKVKVGDHVVVDAASSCADLHCWPHSKFYN 116
Query: 133 ---CENCAKSLYSHCTNGGGWILGYMIDGTQAEYVRTPFADTSLYSVPENLSDEAAVMLS 189
C+ C + + CT+ G LG +I G AE V + + VP+ + + A ++
Sbjct: 117 SKPCDACQRGSENLCTHAGFVGLG-VISGGFAEQVVV--SQHHIIPVPKEIPLDVAALVE 173
Query: 190 DALPTAHEIGVQMGNVKPGDTVAIVGAGPVGMGCVLTSQLYSPSLLIVVDIDDNRLAMAK 249
T H V++ K G + ++GAGP+G+ +L + S ++V +I + R+ MAK
Sbjct: 174 PLSVTWH--AVKISGFKKGSSALVLGAGPIGLCTILVLKGMGASKIVVSEIAERRIEMAK 231
Query: 250 EMGSTHTINSAKEDAVSKILEYTNG-----RGVDCVMEAVGAQATWDICQRVIKEGGHLA 304
++G N +K K +E G G D + G Q T++ + + G
Sbjct: 232 KLG-VEVFNPSKHG--HKSIEILRGLTKSHDGFDYSYDCSGIQVTFETSLKALTFKGTAT 288
Query: 305 NVGVHG-KPVNFEIDKLWIKNLTITSGL 331
N+ V G KPV F+ + ++ +T +
Sbjct: 289 NIAVWGPKPVPFQPMDVTLQEKVMTGSI 316
>7299380 [Q] KOG0022 Alcohol dehydrogenase class III
Length = 379
Score = 98.2 bits (243), Expect = 2e-20
Identities = 87/342 (25%), Positives = 142/342 (41%), Gaps = 46/342 (13%)
Query: 60 IKMTHTSICGTDLGIWKGKNPEIEQTAQTKEGSFNGRILGHEGIGIIDEVGDAVHNFKKG 119
IK+T T +C TD G +PE G F +LGHEG GI++ VG+ V NFK G
Sbjct: 40 IKITATGVCHTDAFTLSGADPE---------GLFPV-VLGHEGAGIVESVGEGVTNFKAG 89
Query: 120 DRVIVSCISRCGTCENCAKSLYSHC-----TNGGG--------------WILGYMIDGTQ 160
D VI I +C C+ C + C T G G + +M T
Sbjct: 90 DHVIALYIPQCNECKFCKSGKTNLCQKIRLTQGAGVMPEGTSRLSCKGQQLFHFMGTSTF 149
Query: 161 AEYVRTPFADTSLYSVPENLSDEAAVMLSDALPTAHEIGVQMGNVKPGDTVAIVGAGPVG 220
AEY T AD SL + E E +L + T + + V+ G T A+ G G VG
Sbjct: 150 AEY--TVVADISLTKINEKAPLEKVCLLGCGISTGYGAALNTAKVEAGSTCAVWGLGAVG 207
Query: 221 MGCVLTSQLYSPSLLIVVDIDDNRLAMAKEMGSTHTIN----SAKEDAVSKILEYTNGRG 276
+ L + + +DI+ ++ +AK+ G T +N + K + +++ T+G G
Sbjct: 208 LAVGLGCKKAGAGKIYGIDINPDKFELAKKFGFTDFVNPKDVADKGSIQNYLIDLTDG-G 266
Query: 277 VDCVMEAVGAQATWDICQRVIKEG-GHLANVGVHG-------KPVNFEIDKLWIKNLTIT 328
D E +G T +G G +GV G +P + ++W +
Sbjct: 267 FDYTFECIGNVNTMRSALEATHKGWGTSVVIGVAGAGQEISTRPFQLVVGRVW--KGSAF 324
Query: 329 SGLVNTNTTGMLMKSCCSGKLKSERLVTHHCNFGEMSGNYNI 370
G + + L++ L + +TH +++ +++
Sbjct: 325 GGWRSVSDVPKLVEDYLKKDLLVDEFITHELPLSQINEAFDL 366
>SPBC1539.07c [Q] KOG0022 Alcohol dehydrogenase class III
Length = 378
Score = 96.3 bits (238), Expect = 7e-20
Identities = 87/315 (27%), Positives = 142/315 (44%), Gaps = 42/315 (13%)
Query: 27 QTNIMKAMVYYGANDIKFEDREQPQILSSTDAIIKMTHTSICGTDLGIWKGKNPEIEQTA 86
+T KA V +GA + + Q + + +K+ +++C TD G +PE
Sbjct: 6 KTITCKAAVAWGAKEPLSIEDIQVAPPKAHEVRVKVDWSAVCHTDAYTLSGVDPE----- 60
Query: 87 QTKEGSFNGRILGHEGIGIIDEVGDAVHNFKKGDRVIVSCISRCGTCENCAKSLYSHC-- 144
G+F +LGHEG GI++ +G+ V N + GD VI+ C C+ C + C
Sbjct: 61 ----GAFP-IVLGHEGAGIVESIGEGVINVRPGDHVILLYTPECKECKFCRSGKTNLCSK 115
Query: 145 ---TNGGGW--------------ILGYMIDGTQAEYVRTPFADTSLYSVPENLSDEAAVM 187
T G G +L YM + ++Y T AD SL ++ + + +
Sbjct: 116 IRETQGRGLMPDGTSRFSCRDKTLLHYMGCSSFSQY--TVVADISLVAISHSAPLRSICL 173
Query: 188 LSDALPTAHEIGVQMGNVKPGDTVAIVGAGPVGMGCVLTSQLYSPSLLIVVDIDDNRLAM 247
L + T V+ G TVA+VG G VG+ + + S +I +DI+ ++
Sbjct: 174 LGCGVTTGFGAVTHSAKVESGSTVAVVGCGCVGLAAMQGAVAAGASRIIAIDINADKEVY 233
Query: 248 AKEMGSTHTINSAK-EDAVSKILEYTNGRGVDCVMEAVG----AQATWDICQRVIKEGGH 302
AK+ G+T I+S+K +D V +++ T+G GVD + G Q C K G
Sbjct: 234 AKKFGATDFIDSSKVKDLVQYVIDVTDG-GVDYAFDCTGNVTVMQQELQFCH---KGWGK 289
Query: 303 LANVGV--HGKPVNF 315
L +GV GK ++F
Sbjct: 290 LCVIGVAAAGKTLDF 304
>At5g43940 [Q] KOG0022 Alcohol dehydrogenase class III
Length = 379
Score = 96.3 bits (238), Expect = 7e-20
Identities = 89/367 (24%), Positives = 148/367 (40%), Gaps = 41/367 (11%)
Query: 32 KAMVYYGANDIKFEDREQPQILSSTDAIIKMTHTSICGTDLGIWKGKNPEIEQTAQTKEG 91
KA V Y N + Q + + IK+ +T++C TD W GK+PE G
Sbjct: 11 KAAVAYEPNKPLVIEDVQVAPPQAGEVRIKILYTALCHTDAYTWSGKDPE---------G 61
Query: 92 SFNGRILGHEGIGIIDEVGDAVHNFKKGDRVIVSCISRCGTCENCAKSLYSHC-----TN 146
F ILGHE GI++ VG+ V + GD VI + C C+ C + C
Sbjct: 62 LFPC-ILGHEAAGIVESVGEGVTEVQAGDHVIPCYQAECRECKFCKSGKTNLCGKVRSAT 120
Query: 147 GGGWILG-------------YMIDGTQAEYVRTPFADTSLYSVPENLSDEAAVMLSDALP 193
G G ++ Y GT T D S+ + + +L +P
Sbjct: 121 GVGIMMNDRKSRFSVNGKPIYHFMGTSTFSQYTVVHDVSVAKIDPTAPLDKVCLLGCGVP 180
Query: 194 TAHEIGVQMGNVKPGDTVAIVGAGPVGMGCVLTSQLYSPSLLIVVDIDDNRLAMAKEMGS 253
T V+PG VAI G G VG+ ++ S +I +DID + AK+ G
Sbjct: 181 TGLGAVWNTAKVEPGSNVAIFGLGTVGLAVAEGAKTAGASRIIGIDIDSKKYETAKKFGV 240
Query: 254 THTINSAKEDAVSK--ILEYTNGRGVDCVMEAVG----AQATWDICQR----VIKEGGHL 303
+N D + I++ T+G GVD E +G +A + C + + G
Sbjct: 241 NEFVNPKDHDKPIQEVIVDLTDG-GVDYSFECIGNVSVMRAALECCHKGWGTSVIVGVAA 299
Query: 304 ANVGVHGKPVNFEIDKLWIKNLTITSGLVNTNTTGMLMKSCCSGKLKSERLVTHHCNFGE 363
+ + +P ++W T G + L++ + ++K + +TH+ GE
Sbjct: 300 SGQEISTRPFQLVTGRVW--KGTAFGGFKSRTQVPWLVEKYMNKEIKVDEYITHNLTLGE 357
Query: 364 MSGNYNI 370
++ +++
Sbjct: 358 INKAFDL 364
>Hs20537182 [Q] KOG0022 Alcohol dehydrogenase class III
Length = 375
Score = 95.9 bits (237), Expect = 9e-20
Identities = 80/316 (25%), Positives = 135/316 (42%), Gaps = 31/316 (9%)
Query: 97 ILGHEGIGIIDEVGDAVHNFKKGDRVIVSCISRCGTCENCAKSLYSHCT-NGGGWILGYM 155
ILGHE GI++ VG+ V K GD+VI +CG C C ++C N G G +
Sbjct: 65 ILGHEAAGIVESVGEGVTTVKPGDKVIPLFTPQCGKCRVCKNPESNYCLKNDLGNPRGTL 124
Query: 156 IDGTQAEYVRTP----FADTSLYSVPENLSDEAAVMLSDALP------------TAHEIG 199
DGT+ R F TS +S + + A + A P T +
Sbjct: 125 QDGTRRFTCRGKPIHHFLGTSTFSQYTVVDENAVAKIDAASPLEKVCLIGCGFSTGYGSA 184
Query: 200 VQMGNVKPGDTVAIVGAGPVGMGCVLTSQLYSPSLLIVVDIDDNRLAMAKEMGSTHTINS 259
V + V PG T A+ G G VG+ V+ + + +I VDI+ ++ A AKE+G+T IN
Sbjct: 185 VNVAKVTPGSTCAVFGLGGVGLSAVMGCKAAGAARIIAVDINKDKFAKAKELGATECINP 244
Query: 260 AK-EDAVSKILEYTNGRGVDCVMEAVGAQATW--------DICQRVIKEGGHLANVGVHG 310
+ + ++L+ GVD E +G T + C + G A+ +
Sbjct: 245 QDYKKPIQEVLKEMTDGGVDFSFEVIGRLDTMMASLLCCHEACGTSVIVGVPPASQNLSI 304
Query: 311 KPVNFEIDKLWIKNLTITSGLVNTNTTGMLMKSCCSGKLKSERLVTHHCNFGEMSGNYNI 370
P+ + W + G + L+ + K + L+TH F +++ +++
Sbjct: 305 NPMLLLTGRTW--KGAVYGGFKSKEGIPKLVADFMAKKFSLDALITHVLPFEKINEGFDL 362
Query: 371 FKHAAEEKAMKLLITF 386
K+++ ++TF
Sbjct: 363 LHSG---KSIRTVLTF 375
>Hs4501929 [Q] KOG0022 Alcohol dehydrogenase class III
Length = 375
Score = 95.5 bits (236), Expect = 1e-19
Identities = 90/351 (25%), Positives = 143/351 (40%), Gaps = 38/351 (10%)
Query: 60 IKMTHTSICGTDLGIWKGKNPEIEQTAQTKEGSFNGRILGHEGIGIIDEVGDAVHNFKKG 119
IKM ICGTD + G T T ILGHE GI++ VG+ V K G
Sbjct: 39 IKMVAVGICGTDDHVVSG-------TMVTPLPV----ILGHEAAGIVESVGEGVTTVKPG 87
Query: 120 DRVIVSCISRCGTCENCAKSLYSHCT-NGGGWILGYMIDGTQAEYVRTP----FADTSLY 174
D+VI I +CG C C ++C N G + DGT R F S +
Sbjct: 88 DKVIPLAIPQCGKCRICKNPESNYCLKNDVSNPQGTLQDGTSRFTCRRKPIHHFLGISTF 147
Query: 175 SVPENLSDEAAVMLSDALP------------TAHEIGVQMGNVKPGDTVAIVGAGPVGMG 222
S + + A + A P T + V + V PG T A+ G G VG+
Sbjct: 148 SQYTVVDENAVAKIDAASPLEKVCLIGCGFSTGYGSAVNVAKVTPGSTCAVFGLGGVGLS 207
Query: 223 CVLTSQLYSPSLLIVVDIDDNRLAMAKEMGSTHTINSAK-EDAVSKILEYTNGRGVDCVM 281
++ + + +I VDI+ ++ A AKE+G+T IN + + ++L+ GVD
Sbjct: 208 AIMGCKAAGAARIIAVDINKDKFAKAKELGATECINPQDYKKPIQEVLKEMTDGGVDFSF 267
Query: 282 EAVGAQATWDICQRVIKEG-GHLANVGVHGKPVNFEIDKLWIK-----NLTITSGLVNTN 335
E +G T E G VGV N ++ + + I G +
Sbjct: 268 EVIGRLDTMMASLLCCHEACGTSVIVGVPPDSQNLSMNPMLLLTGRTWKGAILGGFKSKE 327
Query: 336 TTGMLMKSCCSGKLKSERLVTHHCNFGEMSGNYNIFKHAAEEKAMKLLITF 386
L+ + K + L+TH F +++ +++ K+++ ++ F
Sbjct: 328 CVPKLVADFMAKKFSLDALITHVLPFEKINEGFDLLHSG---KSIRTILMF 375
>At1g22430 [Q] KOG0022 Alcohol dehydrogenase class III
Length = 388
Score = 95.1 bits (235), Expect = 2e-19
Identities = 83/354 (23%), Positives = 156/354 (43%), Gaps = 43/354 (12%)
Query: 60 IKMTHTSICGTDLGIWKGKNPEIEQTAQTKEGSFNGRILGHEGIGIIDEVGDAVHNFKKG 119
IK+ TS+C TDL WK I + RILGHE +G+++ +G+ V FK+G
Sbjct: 45 IKILCTSLCHTDLTFWKLSFGPISRFP---------RILGHEAVGVVESIGENVDGFKQG 95
Query: 120 DRVIVSCISRCGTCENCAKSLYSHC---------------------TNGGGWILGYMIDG 158
D V+ C C++C S + C + G I ++
Sbjct: 96 DVVLPVFHPYCEECKDCKSSKTNWCDRYAEDFISNTRRYGMASRFKDSSGEVIHHFLFVS 155
Query: 159 TQAEYVRTPFADTSLYSVPENLSDEAAVMLSDALPTAHEIGVQMGNVKPGDTVAIVGAGP 218
+ +EY A L + + + A +LS + T ++ NV+ G T+AI G G
Sbjct: 156 SFSEYTVVDIA--HLVKISPEIPVDKAALLSCGVSTGIGAAWKVANVEEGSTIAIFGLGA 213
Query: 219 VGMGCVLTSQLYSPSLLIVVDIDDNRLAMAKEMGSTHTINS--AKEDAVSKILEYTNGRG 276
VG+ ++L + +I +D + ++ + K+ G T IN E +S++++ G
Sbjct: 214 VGLAVAEGARLRGAAKIIGIDTNSDKFELGKKFGFTDFINPTLCGEKKISEVIKEMTEGG 273
Query: 277 VDCVMEAVGAQATWDICQRVIKEG-GHLANVGV--HGKPV---NFEIDKLWIKNLTITSG 330
VD E VG + + + G G +G+ H P+ +F++ + + ++ G
Sbjct: 274 VDYSFECVGLASLLNEAFISTRTGTGKTVMLGMEKHAAPISLGSFDLLRGRVICGSLFGG 333
Query: 331 LVNTNTTGMLMKSCCSGKLKSERLVTHHCNFGEMSGNYNIFKHAAEEKAMKLLI 384
L + +L+ +L + +TH NF E++ + + + E K+++ ++
Sbjct: 334 LKSKLDIPILVDHYLKKELNLDSFITHELNFKEINKAFALLE---EGKSLRCIL 384
>At1g77120 [Q] KOG0022 Alcohol dehydrogenase class III
Length = 379
Score = 94.7 bits (234), Expect = 2e-19
Identities = 93/354 (26%), Positives = 150/354 (42%), Gaps = 44/354 (12%)
Query: 60 IKMTHTSICGTDLGIWKGKNPEIEQTAQTKEGSFNGRILGHEGIGIIDEVGDAVHNFKKG 119
IK+ TS+C TD+ W+ K + RI GHE GI++ VG+ V + + G
Sbjct: 39 IKILFTSLCHTDVYFWEAKG----------QTPLFPRIFGHEAGGIVESVGEGVTDLQPG 88
Query: 120 DRVIVSCISRCGTCENCAKSLYSHC------TNGGGWILG------------YMIDGTQA 161
D V+ CG C +C + C T GG I Y GT
Sbjct: 89 DHVLPIFTGECGECRHCHSEESNMCDLLRINTERGGMIHDGESRFSINGKPIYHFLGTST 148
Query: 162 EYVRTPFADTSLYSVPENLSDEAAVMLSDALPTAHEIGVQMGNVKPGDTVAIVGAGPVGM 221
T + + + + ++S L T + + K G +VAI G G VG+
Sbjct: 149 FSEYTVVHSGQVAKINPDAPLDKVCIVSCGLSTGLGATLNVAKPKKGQSVAIFGLGAVGL 208
Query: 222 GCVLTSQLYSPSLLIVVDIDDNRLAMAKEMGSTHTINSAKEDAVSK--ILEYTNGRGVDC 279
G +++ S +I VD + R AKE G T +N D + I E T+G GVD
Sbjct: 209 GAAEGARIAGASRIIGVDFNSKRFDQAKEFGVTECVNPKDHDKPIQQVIAEMTDG-GVDR 267
Query: 280 VMEAVGA-QATWDICQRVIKEGGHLANVGVHGK-------PVNFEIDKLWIKNLTITSGL 331
+E G+ QA + V G VGV K P+NF +++ +K +
Sbjct: 268 SVECTGSVQAMIQAFECVHDGWGVAVLVGVPSKDDAFKTHPMNF-LNERTLKGTFFGNYK 326
Query: 332 VNTNTTGMLMKSCCSGKLKSERLVTHHCNFGEMSGNYNIFKHAAEEKAMKLLIT 385
T+ G++ K + +L+ E+ +TH F E++ F + + ++++ +IT
Sbjct: 327 PKTDIPGVVEK-YMNKELELEKFITHTVPFSEIN---KAFDYMLKGESIRCIIT 376
>YAL061w [Q] KOG0024 Sorbitol dehydrogenase
Length = 417
Score = 94.0 bits (232), Expect = 3e-19
Identities = 80/302 (26%), Positives = 131/302 (42%), Gaps = 29/302 (9%)
Query: 31 MKAMVYYGANDIKFEDR-EQPQILSSTDAIIKMTHTSICGTDLGIWKGKNPEIEQTAQTK 89
M+A+ Y+G +I+F + ++P I++ + +I + ICGTDL + + T
Sbjct: 1 MRALAYFGKGNIRFTNHLKEPHIVAPDELVIDIEWCGICGTDLHEYTDGPIFFPEDGHTH 60
Query: 90 EGSFNG--RILGHEGIGIIDEVGDAVHNFKKGDRVIVSCISRCGT--------------C 133
E S N + +GHE G + EVG V N K GD+V+V C C
Sbjct: 61 EISHNPLPQAMGHEMAGTVLEVGPGVKNLKVGDKVVVEPTGTCRDRYRWPLSPNVDKEWC 120
Query: 134 ENCAKSLYSHCTNGGGWILGYMIDGTQAEYVRTPFADTSLYSVPENLSDEAAVMLSDALP 193
C K Y+ C+ G G G V ++ Y VP+ + + A ++
Sbjct: 121 AACKKGYYNICSYLGLCGAGVQSGGFAERVVMN---ESHCYKVPDFVPLDVAALIQPLAV 177
Query: 194 TAHEIGVQMGNVKPGDTVAIVGAGPVGMGCVLTSQLYSPSLLIVVDIDDNRLAMAKEMGS 253
H I V K G T I+GAGP+G+G +L ++V + R +A++MG+
Sbjct: 178 CWHAIRVC--EFKAGSTALIIGAGPIGLGTILALNAAGCKDIVVSEPAKVRRELAEKMGA 235
Query: 254 ---THTINSAKE--DAVSKILEYTNGRGVDCVMEAVGAQATWDICQRVIKEGGHLANVGV 308
T ++AKE D + I + G G D + G + T + + + G N+ +
Sbjct: 236 RVYDPTAHAAKESIDYLRSIAD--GGDGFDYTFDCSGLEVTLNAAIQCLTFRGTAVNLAM 293
Query: 309 HG 310
G
Sbjct: 294 WG 295
>Hs4501931 [Q] KOG0022 Alcohol dehydrogenase class III
Length = 375
Score = 94.0 bits (232), Expect = 3e-19
Identities = 91/354 (25%), Positives = 145/354 (40%), Gaps = 44/354 (12%)
Query: 60 IKMTHTSICGTDLGIWKGKNPEIEQTAQTKEGSFNGRILGHEGIGIIDEVGDAVHNFKKG 119
IKM IC TD + GK ILGHE GI++ VG+ V K G
Sbjct: 39 IKMVAVGICRTDDHVVSGKLVTPLPV-----------ILGHEAAGIVESVGEGVTTVKPG 87
Query: 120 DRVIVSCISRCGTCENCAKSLYSHCT-NGGGWILGYMIDGTQAEYVRTP----FADTSLY 174
D+VI +CG C C ++C N G G + DGT+ R F TS +
Sbjct: 88 DKVIPLFTPQCGKCRVCKNPESNYCLKNDLGNPRGTLQDGTRRFTCRGKPIHHFLGTSTF 147
Query: 175 SVPENLSDEAAVMLSDA-------------LPTAHEIGVQMGNVKPGDTVAIVGAGPVGM 221
S + DE AV DA T + V + V PG T A+ G G VG+
Sbjct: 148 S-QYTVVDENAVAKIDAASKLEKVCLIGCGFSTGYGSAVNVAKVTPGSTCAVFGLGGVGL 206
Query: 222 GCVLTSQLYSPSLLIVVDIDDNRLAMAKEMGSTHTINSAK-EDAVSKILEYTNGRGVDCV 280
V+ + + +I VDI+ ++ A AK +G+T IN + + ++L+ GVD
Sbjct: 207 SAVMGCKAAGAARIIAVDINKDKFAKAKVLGATECINPQDYKKPIQEVLKEMTDGGVDFS 266
Query: 281 MEAVGAQATW--------DICQRVIKEGGHLANVGVHGKPVNFEIDKLWIKNLTITSGLV 332
E +G T + C + G A+ + P+ + W + G
Sbjct: 267 FEVIGRLDTMMASLLCCHEACGTSVIVGVPPASQNLSINPMLLLTGRTW--KGAVYGGFK 324
Query: 333 NTNTTGMLMKSCCSGKLKSERLVTHHCNFGEMSGNYNIFKHAAEEKAMKLLITF 386
+ L+ + K + L+TH F +++ +++ K+++ ++TF
Sbjct: 325 SKEGIPKLVADFMAKKFSLDALITHVLPFEKINEGFDLLHSG---KSIRTVLTF 375
>At1g64710 [Q] KOG0022 Alcohol dehydrogenase class III
Length = 380
Score = 94.0 bits (232), Expect = 3e-19
Identities = 96/366 (26%), Positives = 156/366 (42%), Gaps = 46/366 (12%)
Query: 32 KAMVYYGAND-IKFEDR--EQPQILSSTDAIIKMTHTSICGTDLGIWKGKNPEIEQTAQT 88
KA V +GA + + ED + PQ L + I++ TSIC TDL WKG+N Q A
Sbjct: 11 KAAVAWGAGEPLVMEDVKVDPPQRL---EVRIRILFTSICHTDLSAWKGENEA--QRAYP 65
Query: 89 KEGSFNGRILGHEGIGIIDEVGDAVHNFKKGDRVIVSCISRCGTCENCAKSLYSHCTN-G 147
RILGHE GI++ VG+ V GD V+ CG C C + + C
Sbjct: 66 -------RILGHEAAGIVESVGEGVEEMMAGDHVLPIFTGECGDCRVCKRDGANLCERFR 118
Query: 148 GGWILGYMIDGTQAEYVRTP-------FADTSLYSVPENLSDEAAVMLSDALPTAHEI-- 198
+ M+ + + + F +TS +S + D A V+ D L +I
Sbjct: 119 VDPMKKVMVTDGKTRFFTSKDNKPIYHFLNTSTFS-EYTVIDSACVLKVDPLFPLEKISL 177
Query: 199 ---GVQMG--------NVKPGDTVAIVGAGPVGMGCVLTSQLYSPSLLIVVDIDDNRLAM 247
GV G +++P TVAI G G VG+ ++ S +I +DI+ ++ +
Sbjct: 178 LSCGVSTGVGAAWNVADIQPASTVAIFGLGAVGLAVAEGARARGASKIIGIDINPDKFQL 237
Query: 248 AKEMGSTHTINSAKEDAV--SKILEYTNGRGVDCVMEAVGA-QATWDICQRVIKEGGHLA 304
+E G + IN + D +++E T G GV+ E G+ +A + G
Sbjct: 238 GREAGISEFINPKESDKAVHERVMEITEG-GVEYSFECAGSIEALREAFLSTNSGVGVTV 296
Query: 305 NVGVHGKPVNFEIDKLWI---KNLT--ITSGLVNTNTTGMLMKSCCSGKLKSERLVTHHC 359
+GVH P I + + +++T + G + C G L + ++H
Sbjct: 297 MLGVHASPQLLPIHPMELFQGRSITASVFGGFKPKTQLPFFITQCLQGLLNLDLFISHQL 356
Query: 360 NFGEMS 365
F +++
Sbjct: 357 PFHDIN 362
>Hs4507155 [Q] KOG0024 Sorbitol dehydrogenase
Length = 357
Score = 93.6 bits (231), Expect = 4e-19
Identities = 82/353 (23%), Positives = 152/353 (42%), Gaps = 21/353 (5%)
Query: 33 AMVYYGANDIKFEDREQPQILSSTDAIIKMTHTSICGTDLGIWKGKNPEIEQTAQTKEGS 92
++V +G D++ E+ P+ + +++M ICG+D+ W+ + G+
Sbjct: 11 SLVVHGPGDLRLENYPIPEP-GPNEVLLRMHSVGICGSDVHYWE----------YGRIGN 59
Query: 93 F---NGRILGHEGIGIIDEVGDAVHNFKKGDRVIVSCISRCGTCENCAKSLYSHCTNGGG 149
F +LGHE G +++VG +V + K GDRV + + E C Y+ +
Sbjct: 60 FIVKKPMVLGHEASGTVEKVGSSVKHLKPGDRVAIEPGAPRENDEFCKMGRYN-LSPSIF 118
Query: 150 WILGYMIDGTQAEYVRTPFADTSLYSVPENLSDEAAVMLSDALPTAHEIGVQMGNVKPGD 209
+ DG + + A Y +P+N++ E ++ H + G V G
Sbjct: 119 FCATPPDDGNLCRFYKHNAA--FCYKLPDNVTFEEGALIEPLSVGIH--ACRRGGVTLGH 174
Query: 210 TVAIVGAGPVGMGCVLTSQLYSPSLLIVVDIDDNRLAMAKEMGSTHTINSAKE--DAVSK 267
V + GAGP+GM +L ++ + ++V D+ RL+ AKE+G+ + +KE +++
Sbjct: 175 KVLVCGAGPIGMVTLLVAKAMGAAQVVVTDLSATRLSKAKEIGADLVLQISKESPQEIAR 234
Query: 268 ILEYTNGRGVDCVMEAVGAQATWDICQRVIKEGGHLANVGVHGKPVNFEIDKLWIKNLTI 327
+E G + +E GA+A+ + GG L VG+ + + I+ + I
Sbjct: 235 KVEGQLGCKPEVTIECTGAEASIQAGIYATRSGGTLVLVGLGSEMTTVPLLHAAIREVDI 294
Query: 328 TSGLVNTNTTGMLMKSCCSGKLKSERLVTHHCNFGEMSGNYNIFKHAAEEKAM 380
NT + + S + + LVTH + + FK K M
Sbjct: 295 KGVFRYCNTWPVAISMLASKSVNVKPLVTHRFPLEKALEAFETFKKGLGLKIM 347
>Hs4501939 [Q] KOG0022 Alcohol dehydrogenase class III
Length = 368
Score = 93.2 bits (230), Expect = 6e-19
Identities = 65/243 (26%), Positives = 109/243 (44%), Gaps = 27/243 (11%)
Query: 60 IKMTHTSICGTDLGIWKGKNPEIEQTAQTKEGSFNGRILGHEGIGIIDEVGDAVHNFKKG 119
IK+ T +CGT++ + K+ ++ ILGHEG GI++ +G+ V K G
Sbjct: 39 IKVVATGLCGTEMKVLGSKHLDLLYPT----------ILGHEGAGIVESIGEGVSTVKPG 88
Query: 120 DRVIVSCISRCGTCENCAKSLYSHCTNGGGWILGYMIDGTQAEYVRTP----FADTSL-- 173
D+VI + +CG C +C S + C M DGT + F +TS
Sbjct: 89 DKVITLFLPQCGECTSCLNSEGNFCIQFKQSKTQLMSDGTSRFTCKGKSIYHFGNTSTFC 148
Query: 174 -YSVPENLSD---------EAAVMLSDALPTAHEIGVQMGNVKPGDTVAIVGAGPVGMGC 223
Y+V + +S E ++S T + V PG T A+ G G VG+
Sbjct: 149 EYTVIKEISVAKIDAVAPLEKVCLISCGFSTGFGAAINTAKVTPGSTCAVFGLGGVGLSV 208
Query: 224 VLTSQLYSPSLLIVVDIDDNRLAMAKEMGSTHTINSAK-EDAVSKILEYTNGRGVDCVME 282
V+ + + +I VD++ + A+E+G+T +N + + ++L G+D E
Sbjct: 209 VMGCKAAGAARIIGVDVNKEKFKKAQELGATECLNPQDLKKPIQEVLFDMTDAGIDFCFE 268
Query: 283 AVG 285
A+G
Sbjct: 269 AIG 271
>CE22292_2 [Q] KOG0022 Alcohol dehydrogenase class III
Length = 340
Score = 93.2 bits (230), Expect = 6e-19
Identities = 84/342 (24%), Positives = 138/342 (39%), Gaps = 48/342 (14%)
Query: 64 HTSICGTDLGIWKGKNPEIEQTAQTKEGSFNGRILGHEGIGIIDEVGDAVHNFKKGDRVI 123
+TS+C TD G +PE G F +LGHEG GI++ VG V F GD V+
Sbjct: 3 YTSVCHTDAYTLDGHDPE---------GLFPV-VLGHEGSGIVESVGKGVTGFAPGDHVV 52
Query: 124 VSCISRCGTCENCAKSLYSHC-------------------TNGGGWILGYMIDGTQAEYV 164
+ +C CE C + C T G + +M T +EY
Sbjct: 53 PLYVPQCKECEYCKNPKTNMCQKIRVSQGDGFMPDGTSRFTCNGKQLFHFMGCSTFSEY- 111
Query: 165 RTPFADTSLYSVPENLSDEAAVMLSDALPTAHEIGVQMGNVKPGDTVAIVGAGPVGMGCV 224
T AD SL V E +L + T + + V+ G TVA+ G G VG+ +
Sbjct: 112 -TVVADISLCKVNPQAPLEKVSLLGCGISTGYGAVLNTCKVEEGSTVAVWGLGAVGLAVI 170
Query: 225 LTSQLYSPSLLIVVDIDDNRLAMAKEMGSTHTINSAK------EDAVSKILEYTNGRGVD 278
+ ++ ++ +D+ +++ AK G+T IN + S ++E +G G D
Sbjct: 171 MGAKAAGAKKIVGIDLIESKFEKAKMFGATECINPKSVELPEGKSFQSWLVEQFDG-GFD 229
Query: 279 CVMEAVGAQATWDICQRVIKEG-GHLANVGVHG-------KPVNFEIDKLWIKNLTITSG 330
E +G T +G G +GV G +P + W T G
Sbjct: 230 YTFECIGNVHTMRQALEAAHKGWGVSCIIGVAGAGQEIATRPFQLVTGRTW--KGTAFGG 287
Query: 331 LVNTNTTGMLMKSCCSGKLKSERLVTHHCNFGEMSGNYNIFK 372
+ + L+ + KL + +TH CN +++ +++ +
Sbjct: 288 WKSVESVPRLVDDYMNKKLLIDEFITHRCNIDDINAAFDVLR 329
>Hs4501933 [Q] KOG0022 Alcohol dehydrogenase class III
Length = 375
Score = 92.4 bits (228), Expect = 1e-18
Identities = 80/314 (25%), Positives = 135/314 (42%), Gaps = 27/314 (8%)
Query: 97 ILGHEGIGIIDEVGDAVHNFKKGDRVIVSCISRCGTCENCAKSLYSHCT-NGGGWILGYM 155
ILGHE GI++ VG+ V K GD+VI +CG C C ++C N G G +
Sbjct: 65 ILGHEAAGIVESVGEGVTTVKPGDKVIPLFTPQCGKCRICKNPESNYCLKNDLGNPRGTL 124
Query: 156 IDGTQAEYVRTP----FADTSLYSVPENLSDEAAVMLSDALP------------TAHEIG 199
DGT+ F S +S + + A + A P T +
Sbjct: 125 QDGTRRFTCSGKPIHHFVGVSTFSQYTVVDENAVAKIDAASPLEKVCLIGCGFSTGYGSA 184
Query: 200 VQMGNVKPGDTVAIVGAGPVGMGCVLTSQLYSPSLLIVVDIDDNRLAMAKEMGSTHTINS 259
V++ V PG T A+ G G VG+ V+ + + +I VDI+ ++ A AKE+G+T IN
Sbjct: 185 VKVAKVTPGSTCAVFGLGGVGLSVVMGCKAAGAARIIAVDINKDKFAKAKELGATECINP 244
Query: 260 AK-EDAVSKILEYTNGRGVDCVMEAVGAQATWDICQRVIKEG-GHLANVGVHGKPVNFEI 317
+ + ++L+ GVD E +G T E G VGV N I
Sbjct: 245 QDYKKPIQEVLKEMTDGGVDFSFEVIGRLDTMMASLLCCHEACGTSVIVGVPPDSQNLSI 304
Query: 318 DKLWIK-----NLTITSGLVNTNTTGMLMKSCCSGKLKSERLVTHHCNFGEMSGNYNIFK 372
+ + + I G + + L+ + K + L+T+ F +++ +++ +
Sbjct: 305 NPMLLLTGRTWKGAIFGGFKSKESVPKLVADFMAKKFSLDALITNILPFEKINEGFDLLR 364
Query: 373 HAAEEKAMKLLITF 386
K+++ ++TF
Sbjct: 365 SG---KSIRTVLTF 375
>At5g42250 [Q] KOG0022 Alcohol dehydrogenase class III
Length = 390
Score = 91.3 bits (225), Expect = 2e-18
Identities = 75/341 (21%), Positives = 145/341 (41%), Gaps = 42/341 (12%)
Query: 60 IKMTHTSICGTDLGIWKGKNPEIEQTAQTKEGSFNGRILGHEGIGIIDEVGDAVHNFKKG 119
I++ T++C +D+ WK + P + RILGHE IG+++ VG+ V +G
Sbjct: 48 IRIICTALCHSDVTFWKLQVPP----------ACFPRILGHEAIGVVESVGENVKEVVEG 97
Query: 120 DRVIVSCISRCGTCENCAKSLYSHCTN---------------------GGGWILGYMIDG 158
D V+ + + CG C +C + C+ G + ++
Sbjct: 98 DTVLPTFMPDCGDCVDCKSHKSNLCSKFPFKVSPWMPRYDNSSRFTDLNGETLFHFLNVS 157
Query: 159 TQAEYVRTPFADTSLYSVPENLSDEAAVMLSDALPTAHEIGVQMGNVKPGDTVAIVGAGP 218
+ +EY T ++ + ++ A +LS + T + V+ G TV I G G
Sbjct: 158 SFSEY--TVLDVANVVKIDSSIPPSRACLLSCGVSTGVGAAWETAKVEKGSTVVIFGLGS 215
Query: 219 VGMGCVLTSQLYSPSLLIVVDIDDNRLAMAKEMGSTHTINS--AKEDAVSKILEYTNGRG 276
+G+ ++L S +I VDI+ + + ++ G T +NS +++ VS+++ G
Sbjct: 216 IGLAVAEGARLCGASRIIGVDINPTKFQVGQKFGVTEFVNSMTCEKNRVSEVINEMTDGG 275
Query: 277 VDCVMEAVGAQATWDICQRVIKEG-GHLANVGVHGKPVNFEIDKLWIKNL------TITS 329
D E VG+ + ++G G +GV +D + + ++
Sbjct: 276 ADYCFECVGSSSLVQEAYACCRQGWGKTITLGVDKPGSQICLDSFDVLHHGKILMGSLFG 335
Query: 330 GLVNTNTTGMLMKSCCSGKLKSERLVTHHCNFGEMSGNYNI 370
GL +L+K S +L+ ++ VTH F E++ + +
Sbjct: 336 GLKAKTHIPILLKRYLSNELELDKFVTHEMKFEEINDAFQL 376
>At1g22440 [Q] KOG0022 Alcohol dehydrogenase class III
Length = 386
Score = 89.7 bits (221), Expect = 6e-18
Identities = 82/354 (23%), Positives = 152/354 (42%), Gaps = 43/354 (12%)
Query: 60 IKMTHTSICGTDLGIWKGKNPEIEQTAQTKEGSFNGRILGHEGIGIIDEVGDAVHNFKKG 119
IK+ TS+C TD+ WK + + + RILGHE +G+++ +G+ V FK+G
Sbjct: 43 IKILCTSLCHTDVTFWKLDSGPLARFP---------RILGHEAVGVVESIGEKVDGFKQG 93
Query: 120 DRVIVSCISRCGTCENCAKSLYSHCT---------------------NGGGWILGYMIDG 158
D V+ +C C+ C + CT + G I ++
Sbjct: 94 DVVLPVFHPQCEECKECISPKSNWCTKYTNDYLSNTRRYGMTSRFKDSRGEDIHHFIFVS 153
Query: 159 TQAEYVRTPFADTSLYSVPENLSDEAAVMLSDALPTAHEIGVQMGNVKPGDTVAIVGAGP 218
+ EY A L + + + A +LS ++ T ++ +V+ G TV I G G
Sbjct: 154 SFTEYTVVDIA--HLVKISPEIPVDIAALLSCSVATGLGAAWKVADVEEGSTVVIFGLGA 211
Query: 219 VGMGCVLTSQLYSPSLLIVVDIDDNRLAMAKEMGSTHTINSA--KEDAVSKILEYTNGRG 276
VG+ +L + +I VD++ + + K G T +N A E +S+++ G
Sbjct: 212 VGLAVAEGVRLRGAAKIIGVDLNPAKFEIGKRFGITDFVNPALCGEKTISEVIREMTDVG 271
Query: 277 VDCVMEAVGAQATWDICQRVIKEG-GHLANVGVHGKPVNFEI---DKLWIKNL--TITSG 330
D E +G + + + + G G +G+ K + + D L + + T+ G
Sbjct: 272 ADYSFECIGLASLMEEAFKSTRPGSGKTIVLGMEQKALPISLGSYDLLRGRTVCGTLFGG 331
Query: 331 LVNTNTTGMLMKSCCSGKLKSERLVTHHCNFGEMSGNYNIFKHAAEEKAMKLLI 384
L +L+ +L E L+TH +F E++ +++ AE +++ +I
Sbjct: 332 LKPKLDIPILVDRYLKKELNLEDLITHELSFEEINKAFHLL---AEGNSIRCII 382
>CE23822 [Q] KOG0022 Alcohol dehydrogenase class III
Length = 384
Score = 88.6 bits (218), Expect = 1e-17
Identities = 82/344 (23%), Positives = 140/344 (39%), Gaps = 48/344 (13%)
Query: 60 IKMTHTSICGTDLGIWKGKNPEIEQTAQTKEGSFNGRILGHEGIGIIDEVGDAVHNFKKG 119
+K+ +T++C TD G +PE G F +LGHEG GI++ VG+ V F G
Sbjct: 40 VKILYTAVCHTDAYTLDGHDPE---------GLFPV-VLGHEGSGIVESVGEGVTGFAPG 89
Query: 120 DRVIVSCISRCGTCENCAKSLYSHC-------------------TNGGGWILGYMIDGTQ 160
D V+ + +C CE C + C T G + +M T
Sbjct: 90 DHVVPLYVPQCKECEYCKNPKTNLCQKIRISQGNGFMPDGSSRFTCNGKQLFHFMGCSTF 149
Query: 161 AEYVRTPFADTSLYSVPENLSDEAAVMLSDALPTAHEIGVQMGNVKPGDTVAIVGAGPVG 220
+EY T AD SL V E +L + T + + V+ G TVA+ G G VG
Sbjct: 150 SEY--TVVADISLCKVNPEAPLEKVSLLGCGISTGYGAVLNTCKVEEGSTVAVWGLGAVG 207
Query: 221 MGCVLTSQLYSPSLLIVVDIDDNRLAMAKEMGSTHTINSAK------EDAVSKILEYTNG 274
+ ++ ++ ++ +D+ +++ AK G+T IN + + ++E +G
Sbjct: 208 LAVIMGAKAAGAKKIVGIDLIESKFESAKFFGATECINPKSVELPEGKSFQAWLVEQFDG 267
Query: 275 RGVDCVMEAVGAQATWDICQRVIKEG-GHLANVGVHG-------KPVNFEIDKLWIKNLT 326
G D E +G T +G G +GV G +P + W T
Sbjct: 268 -GFDYTFECIGNVHTMRQALEAAHKGWGVSCIIGVAGAGQEIATRPFQLVTGRTW--KGT 324
Query: 327 ITSGLVNTNTTGMLMKSCCSGKLKSERLVTHHCNFGEMSGNYNI 370
G + + L+ + KL + +TH N +++ +++
Sbjct: 325 AFGGWKSVESVPRLVDDYMNKKLLIDEFITHRWNIDDINTAFDV 368
>Hs4501935 [Q] KOG0022 Alcohol dehydrogenase class III
Length = 392
Score = 88.2 bits (217), Expect = 2e-17
Identities = 86/358 (24%), Positives = 146/358 (40%), Gaps = 47/358 (13%)
Query: 60 IKMTHTSICGTDLGIWKGKNPEIEQTAQTKEGSFNGRILGHEGIGIIDEVGDAVHNFKKG 119
I++ TS+C TD + K EG I+GHE GI++ +G V N K G
Sbjct: 39 IQIIATSLCHTDASVIDSKF----------EGLAFPVIVGHEAAGIVESIGPGVTNVKPG 88
Query: 120 DRVIVSCISRCGTCENCAKSLYSHC-----------------------TNGGGWILGYMI 156
D+VI C C+ C L + C T G + +
Sbjct: 89 DKVIPLYAPLCRKCKFCLSPLTNLCGKISNLKSPASDQQLMEDKTSRFTCKGKPVYHFFG 148
Query: 157 DGTQAEYVRTPFADTSLYSVPENLSDEAAVMLSDALPTAHEIGVQMGNVKPGDTVAIVGA 216
T ++Y T +D +L + ++ + E +L T + + V PG T A+ G
Sbjct: 149 TSTFSQY--TVVSDINLAKIDDDANLERVCLLGCGFSTGYGAAINNAKVTPGSTCAVFGL 206
Query: 217 GPVGMGCVLTSQLYSPSLLIVVDIDDNRLAMAKEMGSTHTIN--SAKEDAVSKILEYTNG 274
G VG+ V+ + S +I +DI+ + AK +G+T +N + I+E T G
Sbjct: 207 GGVGLSAVMGCKAAGASRIIGIDINSEKFVKAKALGATDCLNPRDLHKPIQEVIIELTKG 266
Query: 275 RGVDCVMEAVGAQATWDICQRVIKEG-GHLANVGV--HGKPVNFEIDKLWIK---NLTIT 328
GVD ++ G T G G +GV K + ++L I N T
Sbjct: 267 -GVDFALDCAGGSETMKAALDCTTAGWGSCTFIGVAAGSKGLTIFPEELIIGRTINGTFF 325
Query: 329 SGLVNTNTTGMLMKSCCSGKLKSERLVTHHCNFGEMSGNYNIFKHAAEEKAMKLLITF 386
G + ++ L+ + K + LVTH F ++S +++ + K+++ ++ F
Sbjct: 326 GGWKSVDSIPKLVTDYKNKKFNLDALVTHTLPFDKISEAFDLMN---QGKSVRTILIF 380
>SPBC1773.06c [CR] KOG1198 Zinc-binding oxidoreductase
Length = 346
Score = 87.8 bits (216), Expect = 2e-17
Identities = 92/312 (29%), Positives = 136/312 (43%), Gaps = 34/312 (10%)
Query: 38 GANDIKFEDREQPQILSSTDAIIKMTHTSICGTDLGIWKGKNPEIEQTAQTKEGSFNGRI 97
G + +K E+ E PQ L+ + ++K+ S+ DL I KG P Q +
Sbjct: 13 GFDQLKPEEYEVPQKLNPGEVLVKLKAASLNYRDLIITKGLYPLPLQLPV---------V 63
Query: 98 LGHEGIGIIDEVGDAVHNFKKGDRVIVSCISRCGTCENCAKSLYSHCTNGGGWILGYMID 157
G +G GII++VG+ V F+KGD V+ C + +H GG D
Sbjct: 64 PGSDGAGIIEKVGEDVEGFEKGDSVV--CNFFTNYLDGTPTDFATHSALGG------TRD 115
Query: 158 GTQAEYVRTPFADTSLYSVPENLSDEAAVMLSDALPTAHE--IGVQMGNVKPGDTVAIVG 215
G +Y P +L P+NLS E L A TA G + VKPG+ V ++G
Sbjct: 116 GCFQKYAVLP--AHALVHAPKNLSFEEIATLPCAAVTAWNGLFGSKEHQVKPGNNVLVLG 173
Query: 216 AGPVGMGCVLTSQLYSPSLLIVVDIDDNRLAMAKEMGSTHTINSAKEDA-VSKILEYTNG 274
G V L L + + + V D +L AK++G+THTIN K S L+ TNG
Sbjct: 174 TGGVST-FALQFALAAGANVTVTSSSDEKLEFAKKLGATHTINYKKTPQWASPALKMTNG 232
Query: 275 RGVDCVMEAVGAQATWDICQRVIKEGGHLANVGVHGKPVNFEIDKLWIKNLTITSGLV-- 332
G V+E VG + T + + G ++ +G F + NLT G +
Sbjct: 233 VGYHHVIE-VGGEKTLPQSIACLAKDGMISMIG-------FVASEGTTPNLTSIIGQILN 284
Query: 333 -NTNTTGMLMKS 343
N N G+ + S
Sbjct: 285 RNANIRGIFVGS 296
>YLR070c [Q] KOG0024 Sorbitol dehydrogenase
Length = 356
Score = 87.0 bits (214), Expect = 4e-17
Identities = 72/284 (25%), Positives = 127/284 (44%), Gaps = 22/284 (7%)
Query: 50 PQILSSTDAIIKMTHTSICGTDLGIW---KGKNPEIEQTAQTKEGSFNGRILGHEGIGII 106
P+I + II++ T ICG+D+ + + N +E +LGHE GI+
Sbjct: 26 PKISDPNEVIIQIKATGICGSDIHYYTHGRIANYVVESPM----------VLGHESSGIV 75
Query: 107 DEVGDAVHNFKKGDRVIVSCISRCGTCENCAKSLYSHCTNGGGWILGYMIDGTQAEYVRT 166
+G+ V K GDRV + + Y+ N + DGT +Y +T
Sbjct: 76 ALIGENVKTLKVGDRVALEPGIPDRFSPEMKEGRYNLDPNLK-FAATPPFDGTLTKYYKT 134
Query: 167 PFADTSLYSVPENLSDEAAVMLSDALPTAHEIGVQMGNVKPGDTVAIVGAGPVGMGCVLT 226
+Y +P+++S E ++ H ++ +K G + GAGP+G+
Sbjct: 135 --MKDFVYKLPDDVSFEEGALIEPLSVAIH--ANKLAKIKFGARCVVFGAGPIGLLAGKV 190
Query: 227 SQLYSPSLLIVVDIDDNRLAMAKEMGSTHTINSAKED---AVSKILEYTNG-RGVDCVME 282
+ ++ + ++ VD+ +N+L A++ G+TH +NS V +++ G +G D V E
Sbjct: 191 ASVFGAADVVFVDLLENKLETARQFGATHIVNSGDLPHGVTVDSVIKKAIGKKGADVVFE 250
Query: 283 AVGAQATWDICQRVIKEGGHLANVGVHGKPVNFEIDKLWIKNLT 326
GA+ V K GG + VG+ + + F I + K LT
Sbjct: 251 CSGAEPCVRAGIEVCKAGGTIVQVGMGQEEIQFPISIIPTKELT 294
>Hs4501941 [Q] KOG0022 Alcohol dehydrogenase class III
Length = 374
Score = 87.0 bits (214), Expect = 4e-17
Identities = 84/351 (23%), Positives = 146/351 (40%), Gaps = 39/351 (11%)
Query: 60 IKMTHTSICGTDLGIWKGKNPEIEQTAQTKEGSFNGRILGHEGIGIIDEVGDAVHNFKKG 119
IK+ T IC TD + KG T F I+GHE GI++ +G+ V K G
Sbjct: 39 IKILATGICRTDDHVIKG----------TMVSKFPV-IVGHEATGIVESIGEGVTTVKPG 87
Query: 120 DRVIVSCISRCGTCENCAKSLYSHCTNGGGWILGYMIDGTQAEYVRTP----FADTSLYS 175
D+VI + +C C C + C G + DGT + F +TS ++
Sbjct: 88 DKVIPLFLPQCRECNACRNPDGNLCIRSDITGRGVLADGTTRFTCKGKPVHHFMNTSTFT 147
Query: 176 VPENLSDEAAVMLSDALP------------TAHEIGVQMGNVKPGDTVAIVGAGPVGMGC 223
+ + + + DA P T + V+ G VKPG T + G G VG+
Sbjct: 148 EYTVVDESSVAKIDDAAPPEKVCLIGCGFSTGYGAAVKTGKVKPGSTCVVFGLGGVGLSV 207
Query: 224 VLTSQLYSPSLLIVVDIDDNRLAMAKEMGSTHTINSAKEDA--VSKILEYTNGRGVDCVM 281
++ + S +I +D++ ++ A +G+T I S K+ +S++L G V
Sbjct: 208 IMGCKSAGASRIIGIDLNKDKFEKAMAVGATECI-SPKDSTKPISEVLSEMTGNNVGYTF 266
Query: 282 EAVGAQATW-DICQRVIKEGGHLANVGV--HGKPVNFEIDKLWIKNL---TITSGLVNTN 335
E +G T D G VGV K + ++ L+ + GL + +
Sbjct: 267 EVIGHLETMIDALASCHMNYGTSVVVGVPPSAKMLTYDPMLLFTGRTWKGCVFGGLKSRD 326
Query: 336 TTGMLMKSCCSGKLKSERLVTHHCNFGEMSGNYNIFKHAAEEKAMKLLITF 386
L+ + K ++L+TH F ++S + + ++++ ++TF
Sbjct: 327 DVPKLVTEFLAKKFDLDQLITHVLPFKKISEGFELLNSG---QSIRTVLTF 374
>At1g32780 [Q] KOG0022 Alcohol dehydrogenase class III
Length = 362
Score = 84.3 bits (207), Expect = 3e-16
Identities = 66/226 (29%), Positives = 98/226 (43%), Gaps = 36/226 (15%)
Query: 60 IKMTHTSICGTDLGIWKGKNPEIEQTAQTKEGSFNGRILGHEGIGIIDEVGDAVHNFKKG 119
+K+ ++SIC TDLG W G N E E+ RILGHE +GI++ VG+ V + K+G
Sbjct: 40 VKILYSSICHTDLGCWNGTN-EAERAFP--------RILGHEAVGIVESVGEGVKDVKEG 90
Query: 120 DRVIVSCISRCGTCENCAKSLYSHC------------TNGGGWILGYMID---GTQAEYV 164
D VI + CG C+ C + + C N GG I+ G+
Sbjct: 91 DYVIPTFNGECGECKVCKREESNLCERYHVDPMKRVMVNDGGTRFSTTINKDGGSSQSQP 150
Query: 165 RTPFADTSLYSVPENLSDEAAV------------MLSDALPTAHEIGVQMGNVKPGDTVA 212
F +TS ++ L V +LS + T + NVK G + A
Sbjct: 151 IYHFLNTSTFTEYTVLDSACVVKIDPNSPLKQMSLLSCGVSTGVGAAWNIANVKEGKSTA 210
Query: 213 IVGAGPVGMGCVLTSQLYSPSLLIVVDIDDNRLAMAKEMGSTHTIN 258
+ G G VG+ ++ S +I VD + ++ K MG T IN
Sbjct: 211 VFGLGSVGLAVAEGARARGASRIIGVDANASKFEKGKLMGVTDFIN 256
>SPCC13B11.04c [Q] KOG0022 Alcohol dehydrogenase class III
Length = 380
Score = 82.4 bits (202), Expect = 1e-15
Identities = 77/326 (23%), Positives = 133/326 (40%), Gaps = 42/326 (12%)
Query: 60 IKMTHTSICGTDLGIWKGKNPEIEQTAQTKEGSFNGRILGHEGIGIIDEVGDAVHNFKKG 119
IK+ ++ +C TD GK+PE G F ILGHEG GI++ VG V + G
Sbjct: 42 IKIVNSGVCHTDAYTLSGKDPE---------GLFPV-ILGHEGAGIVESVGPQVTTVQVG 91
Query: 120 DRVIVSCISRCGTCENCAKSLYSHC-----TNG--------------GGWILGYMIDGTQ 160
D VI C TC+ C + C T G G +L +M T
Sbjct: 92 DPVIALYTPECKTCKFCKSGKTNLCGRIRTTQGKGLMPDGTSRFSCNGNTLLHFMGCSTF 151
Query: 161 AEYVRTPFADTSLYSVPENLSDEAAVMLSDALPTAHEIGVQMGNVKPGDTVAIVGAGPVG 220
+EY T AD S+ ++ ++ +L + T + ++K GD+VA+ G G VG
Sbjct: 152 SEY--TVVADISVVAIERLAPLDSVCLLGCGITTGYGAATITADIKEGDSVAVFGLGSVG 209
Query: 221 MGCVLTSQLYSPSLLIVVDIDDNRLAMAKEMGSTHTIN-SAKEDAVSKILEYTNGRGVDC 279
+ + + + +D++ + A G+T IN + + + +L + G+D
Sbjct: 210 LAVIQGAVKKRAGRIFGIDVNPEKKNWAMSFGATDFINPNDLQSPIQDVLIHETDGGLDW 269
Query: 280 VMEAVG----AQATWDICQR----VIKEGGHLANVGVHGKPVNFEIDKLWIKNLTITSGL 331
+ G ++ + C + I G A + +P ++W G+
Sbjct: 270 TFDCTGNVHVMRSALEACHKGWGQSIVIGVAAAGQEISTRPFQLVTGRVW--RGCAFGGV 327
Query: 332 VNTNTTGMLMKSCCSGKLKSERLVTH 357
+ L+K KL+ ++ +TH
Sbjct: 328 KGRSQLPDLVKEYLDHKLEIDKYITH 353
>At4g22110 [Q] KOG0022 Alcohol dehydrogenase class III
Length = 378
Score = 80.9 bits (198), Expect = 3e-15
Identities = 79/340 (23%), Positives = 143/340 (41%), Gaps = 51/340 (15%)
Query: 60 IKMTHTSICGTDLGIWKGKNPEIEQTAQTKEGSFNGRILGHEGIGIIDEVGDAVHNFKKG 119
IK+ TS+C TD+ K I HE +G+I+ +G+ V+ F++G
Sbjct: 46 IKIICTSLCHTDVSFSK--------------------IDRHEAVGVIESIGEHVNGFQQG 85
Query: 120 DRVIVSCISRCGTCENCAKSLYSHCT---------------------NGGGWILGYMIDG 158
D V+ C C +C S + C + G I ++
Sbjct: 86 DVVLPVFHPHCEECRDCKSSKSNWCARFADDFLSNTRRYGMTSRFKDSFGEDIYHFLFVS 145
Query: 159 TQAEYVRTPFADTSLYSVPENLSDEAAVMLSDALPTAHEIGVQMGNVKPGDTVAIVGAGP 218
+ +EY A L + ++ + A +LS + T ++ NV+ G TVA+ G G
Sbjct: 146 SFSEYTVVDIAH--LVKISPDIPVDKAALLSCGVSTGIGAAWKVANVEKGSTVAVFGLGA 203
Query: 219 VGMGCVLTSQLYSPSLLIVVDIDDNRLAMAKEMGSTHTINS--AKEDAVSKILEYTNGRG 276
VG+ ++L +I VD++ + + K+ G T INS E+ +S++++ G G
Sbjct: 204 VGLAVGEGARLRGAGKIIGVDLNPEKFELGKKFGFTDFINSTLCGENKISEVIKEMTGGG 263
Query: 277 VDCVMEAVGAQATWDICQRVIKEG-GHLANVGV--HGKPVNF-EIDKLWIKNL--TITSG 330
VD E VG + + G G +G+ H PV+ D L +++ ++ G
Sbjct: 264 VDYSFECVGLPSLLTEAFSSTRTGSGKTVVLGIDKHLTPVSLGSFDLLRGRHVCGSLFGG 323
Query: 331 LVNTNTTGMLMKSCCSGKLKSERLVTHHCNFGEMSGNYNI 370
L +L+ +L + +TH F E++ +++
Sbjct: 324 LKPKLDIPILVDHYLKKELNLDSFITHELKFEEINKAFDL 363
>YBR046c [CR] KOG1197 Predicted quinone oxidoreductase
Length = 334
Score = 78.6 bits (192), Expect = 1e-14
Identities = 80/295 (27%), Positives = 128/295 (43%), Gaps = 50/295 (16%)
Query: 38 GANDIKFEDREQPQILSSTDAIIKMTHTSICGTDLGIWKGKNPEIEQTAQTKEGSFNGRI 97
G + IK+ED P I S + +IK +T + + KG P +
Sbjct: 19 GYDVIKYEDYPVPSI-SEEELLIKNKYTGVNYIESYFRKGIYP-----------CEKPYV 66
Query: 98 LGHEGIGIIDEVGDAVHNFKKGDRVIVSCISRCGTCENCAKSLYSHCTNGGGWILGYMID 157
LG E G + G V NF+ GD+V Y+ +
Sbjct: 67 LGREASGTVVAKGKGVTNFEVGDQV------------------------------AYISN 96
Query: 158 GTQAEYVRTPFADTSLYSVPENLSDEAAVMLSDALP---TAHEIGVQMGNVKPGDTVAIV 214
T A+Y + + + +P+ SDE + + L TA + +VK GD V +
Sbjct: 97 STFAQYSKIS-SQGPVMKLPKGTSDEELKLYAAGLLQVLTALSFTNEAYHVKKGDYVLLF 155
Query: 215 GAGPVGMGCVLTSQLYSPSL-LIVVDIDDNRLAMAKEMGSTHTINSAKEDAVSKILEYTN 273
A G+G +L L I V D +L +AKE G+ + IN++KED + ++L++TN
Sbjct: 156 AAAG-GVGLILNQLLKMKGAHTIAVASTDEKLKIAKEYGAEYLINASKEDILRQVLKFTN 214
Query: 274 GRGVDCVMEAVGAQATWDICQRVIKEGGHLANVG-VHGKPVNFEIDKLWIKNLTI 327
G+GVD ++VG + T++I +K G + G G F I +L KN+T+
Sbjct: 215 GKGVDASFDSVG-KDTFEISLAALKRKGVFVSFGNASGLIPPFSITRLSPKNITL 268
>SPBC1773.05c [Q] KOG0024 Sorbitol dehydrogenase
Length = 360
Score = 78.6 bits (192), Expect = 1e-14
Identities = 90/375 (24%), Positives = 146/375 (38%), Gaps = 47/375 (12%)
Query: 32 KAMVYYGANDIKFEDREQPQILSSTDAIIKMTHTSICGTDLGIWKGKNPEIEQTAQTKEG 91
KA V D EDR + + + T ICG+D+ WK + G
Sbjct: 6 KAFVLRKKMDTAIEDRPGQTLTDDHQVKVAIKATGICGSDVHYWK----------EGGIG 55
Query: 92 SF---NGRILGHEGIGIIDEVGDAVHNFKKGDRVIVSCISRCGTCENCAKSLYSHCTNGG 148
F ILGHE G++ EVG V + K GD V V C C+ C Y+ C +
Sbjct: 56 DFILKKPMILGHESAGVVVEVGKGVSSLKPGDPVAVEPGCVCRLCDYCRSGRYNLCPH-M 114
Query: 149 GWILGYMIDGTQAEYVRTPFADTSLYSVPENLSDEAAVMLSDALPTAHEIGVQMGNVKPG 208
+ DGT Y T + +P+ +S E + H + GN+K G
Sbjct: 115 EFAATPPYDGTLRTYYIT--TEDFCTKLPKQISVEEGALFEPMSVAVH--AMTRGNLKCG 170
Query: 209 DTVAIVGAGPVGMGCVLTSQLYSPSLLIVVDIDDNRLAMAKEM--GSTHTINSAKED--- 263
V ++G G VG+ + ++ Y ++ VD +R+ A++ T +AKE+
Sbjct: 171 SRVLVMGCGTVGLLMMAVAKAYGAIDIVAVDASPSRVEFAQKYVGAKPFTPIAAKENESL 230
Query: 264 ----------AVSKILEYTNGRGVDCVMEAVGAQATWDICQRVIKEGGHLANVGVHGKPV 313
+ K E+ D ++A G +K GG G +GKPV
Sbjct: 231 PDYAQRYKQAIIEKYGEF------DFAVDATGVGICIHTAVLALKRGGTFVQAG-NGKPV 283
Query: 314 -NFEIDKLWIKNLTITSGLVNTNTTGMLMKS---CCSGKLKSERLVTHHCNFGEMSGNYN 369
+F I+ + + + + G +S +G + + L+TH F + Y
Sbjct: 284 IDFPINHIINYEINVLGSFRYAH--GCYKQSLFLVSNGLVDVKPLITHRFAFKDALKAYE 341
Query: 370 IFKHAAEEKAMKLLI 384
+ EE +K++I
Sbjct: 342 TVA-SGEEGVLKVII 355
>SPCC13B11.01 [Q] KOG0023 Alcohol dehydrogenase class V
Length = 350
Score = 78.2 bits (191), Expect = 2e-14
Identities = 66/240 (27%), Positives = 113/240 (46%), Gaps = 19/240 (7%)
Query: 38 GANDIKFEDREQPQILSSTDAIIKMTHTSICGTDLGIWKGKNPEIEQTAQTKEGSFNGRI 97
G ++KFE+ + + ++ + +T +C TDL +G P + I
Sbjct: 17 GPENVKFEEVPVAEP-GQDEVLVNIKYTGVCHTDLHALQGDWPLPAKMPL---------I 66
Query: 98 LGHEGIGIIDEVGDAVHNFKKGDRVIVSCI-SRCGTCENCAKSLYSHCTNGGGWILGYMI 156
GHEG G++ +VG V K GDRV V + S CG CE C K+ + C + + GY +
Sbjct: 67 GGHEGAGVVVKVGAGVTRLKIGDRVGVKWMNSSCGNCEYCMKAEETICPH--IQLSGYTV 124
Query: 157 DGTQAEYVRTPFADTSLYSVPENLSDEAAVMLSDALPTAHEIGVQMGNVKPGDTVAIVGA 216
DGT Y ++ +PE++ E A + A T + ++ V PG+ + I GA
Sbjct: 125 DGTFQHYCIANATHATI--IPESVPLEVAAPIMCAGITCYR-ALKESKVGPGEWICIPGA 181
Query: 217 GPVGMGCVLTSQLYSPSLLIV-VDIDDNRLAMAKEMGSTHTINSAKE-DAVSKILEYTNG 274
G G+G + + ++ +V +D D++ + K G+ ++ KE D + + TNG
Sbjct: 182 GG-GLGHLAVQYAKAMAMRVVAIDTGDDKAELVKSFGAEVFLDFKKEADMIEAVKAATNG 240
>7300579 [Q] KOG0024 Sorbitol dehydrogenase
Length = 1139
Score = 71.6 bits (174), Expect = 2e-12
Identities = 65/306 (21%), Positives = 126/306 (40%), Gaps = 31/306 (10%)
Query: 57 DAIIKMTHTSICGTDLGIWKGKNPEIEQTAQTKEGSFNGRILGHEGIGIIDEVGDAVHNF 116
D +I+ ++ +D+ +++ N ++E + LGH+ GI++E+G V +
Sbjct: 823 DVLIRTGSVAVSNSDIHVYENGNRDMEAMS-----------LGHDATGIVEELGRCVQHL 871
Query: 117 KKGDRVIVSCISRCGTCENCAKSLYSHCTNGGGWILGYMIDGTQAEYVRTPFADTSLYSV 176
GDRV++ CG C+ C K LY+ C+ G + +G + Y P AD + +
Sbjct: 872 HVGDRVVMESALSCGICDLCKKGLYNMCS-------GLVYNGFLSTYQTHP-ADL-CHRL 922
Query: 177 PENLSDEAAVMLSDALPTAHEIGVQ---MGNVKPGDTVAIVGAGPVGMGCVLTSQLYSPS 233
PE++S EA AL +G Q NV P V I+GA P + + ++
Sbjct: 923 PESISMEAG-----ALTQTLALGCQACFKANVTPTSNVLILGACPTAVAAGICAKAIGAK 977
Query: 234 LLIVVDIDDNRLAMAKEMGSTHTINSAKEDAVSKILE--YTNGRG-VDCVMEAVGAQATW 290
+ + L + + ++LE Y+ R DCV+ + T
Sbjct: 978 RVAIAGCMAPALDVVARDFGFQAVEFDSNALFGEVLEAIYSKFRDWPDCVINCSISAMTM 1037
Query: 291 DICQRVIKEGGHLANVGVHGKPVNFEIDKLWIKNLTITSGLVNTNTTGMLMKSCCSGKLK 350
++ ++ G + +F + +KN+ + + N ++ SG+
Sbjct: 1038 NLAVMALQPCGVCVLAECDSECASFNALDVLMKNIRLVPSFRSANMYPTALQLMQSGRAH 1097
Query: 351 SERLVT 356
++ +T
Sbjct: 1098 MQKFIT 1103
>CE12212 [Q] KOG0023 Alcohol dehydrogenase class V
Length = 349
Score = 68.6 bits (166), Expect = 2e-11
Identities = 67/284 (23%), Positives = 125/284 (43%), Gaps = 25/284 (8%)
Query: 57 DAIIKMTHTSICGTDLGIWKGKNPEIEQTAQTKEGSFNGRILGHEGIGIIDEVGDAVHNF 116
+ ++K+ ++ IC +DL +W G K+ S + GHEG G + ++G V +
Sbjct: 35 EILVKIEYSGICHSDLHVWLG---------DLKDMSVCPLVGGHEGAGSVVQIGKNVTGW 85
Query: 117 KKGDRVIVSCIS-RCGTCENCAKS---LYSHCTNGGGWILGYMIDGTQAEYVRTPFADTS 172
+ GD+ V ++ C CE C K L H N G+ GT EY+ D +
Sbjct: 86 QLGDKAGVKLMNFNCLNCEFCKKGHEPLCHHIQN-----YGFDRSGTFQEYLTIRGVDAA 140
Query: 173 LYSVPENLSDEAAVMLSDALPTAHEIGVQMGNVKPGDTVAIVGAGPVGMGCVLTSQLYSP 232
+ NL+ A ++ + T ++ ++ NV PG + + GAG G+G + +
Sbjct: 141 KINKDTNLAAAAPILCAGV--TVYK-ALKESNVAPGQIIVLTGAGG-GLGSLAIQYACAM 196
Query: 233 SLLIVVDIDDNRLAMAKEMGSTHTINSAK-EDAVSKILEYTNGRGVDCVMEAVGAQATWD 291
+ +V ++ A K +G+ +++ + D VS I + T G G V+ A+ +
Sbjct: 197 GMRVVAMDHGSKEAHCKGLGAEWFVDAFETPDIVSHITKLTEG-GPHGVINFAVARKPME 255
Query: 292 ICQRVIKEGGHLANVGV-HGKPVNFEIDKLWIKNLTITSGLVNT 334
+++ G + VG+ V F+ +TI +V +
Sbjct: 256 QAVEYVRKRGTVVFVGLPKDSKVTFDTTPFIFNAITIKGSIVGS 299
>CE12214 [Q] KOG0023 Alcohol dehydrogenase class V
Length = 351
Score = 68.2 bits (165), Expect = 2e-11
Identities = 71/277 (25%), Positives = 119/277 (42%), Gaps = 25/277 (9%)
Query: 36 YYGANDIKFEDREQPQILSSTDAIIKMTHTSICGTDLGIWKGKNPEIEQTAQTKEGSFNG 95
Y G +++ QPQ + ++K+ ++ IC +DL W+G + S
Sbjct: 18 YGGPLEVRQVSVPQPQ---ENELLVKIEYSGICHSDLHTWEG---------DFEYASICP 65
Query: 96 RILGHEGIGIIDEVGDAVHNFKKGDRVIVSCI-SRCGTCENCAKSLYSHCTNGGGWILGY 154
I GHEG G + +G V + GDR + I + C CE C C + I Y
Sbjct: 66 LIGGHEGAGTVVTIGSKVKGWNIGDRAGIKLINANCLNCEYCKTGHEPLCDH----IQNY 121
Query: 155 MID--GTQAEYVRTPFADTSLYSVPENLSDEAAVMLSDALPTAHEIGVQMGNVKPGDTVA 212
ID GT EY+ D S NL+ A V+ TA++ ++ NVKPG V
Sbjct: 122 GIDRHGTFQEYLTIRDIDAIKVSNDTNLAAAAPVLCGGV--TAYK-SLKATNVKPGQIVV 178
Query: 213 IVGAGPVGMGCVLTSQLYSPSLLIVVDIDDNRLAMAKEMGSTHTINS-AKEDAVSKILEY 271
+ GAG G+G + + +V ++ + +G+ +++ D V+ I +
Sbjct: 179 LTGAGG-GLGSFGIQYAKAMGMRVVAVDHISKEDHCRNLGAEWFVDAFDTPDIVAHIRKL 237
Query: 272 TNGRGVDCVMEAVGAQATWDICQRVIKEGGHLANVGV 308
TNG G V+ A+ + +++ G + VG+
Sbjct: 238 TNG-GAHGVVSFAAAKKPMEYALEYVRKRGTVVFVGL 273
>CE20628 [Q] KOG0023 Alcohol dehydrogenase class V
Length = 408
Score = 67.8 bits (164), Expect = 3e-11
Identities = 70/291 (24%), Positives = 120/291 (41%), Gaps = 37/291 (12%)
Query: 36 YYGANDIKFEDREQPQILSSTDAIIKMTHTSICGTDLGIWKGKNPEIEQTAQTKEGSFNG 95
Y G +IK QP + + ++KM ++ IC +D+ W G + +
Sbjct: 18 YGGPLEIKQLPIPQP---NEDELLVKMEYSGICHSDVHTWLGDFHYVSKCPM-------- 66
Query: 96 RILGHEGIGIIDEVGDAVHNFKKGDRVIVSCI-----------------SRCGTCENCAK 138
I GHEG G + VG V N++ GD+V + C CE C
Sbjct: 67 -IGGHEGAGSVISVGSKVKNWQIGDKVGIKVSQTLNSSSLNFNIFQLVQGNCLNCEYCQT 125
Query: 139 SLYSHCTNGGGWILGYMIDGTQAEYVRTPFADTSLYSVPENLSDEAAVMLSDALPTAHEI 198
C + W +G GT EY D +P++++ AA + TA++
Sbjct: 126 GHEPLCPH--VWNIGVQKYGTFQEY--ATIRDVDAIKIPKSMNMAAAAPVLCGGVTAYK- 180
Query: 199 GVQMGNVKPGDTVAIVGAGPVGMGCVLTSQLYSPSLLIVVDIDDNRLAMAKEMGSTHTIN 258
++ VK G VA+ GAG G+G + + +V ++ A K +G+ ++
Sbjct: 181 ALKESEVKSGQIVAVTGAGG-GLGSFAIQYARAMGMRVVAIDHPSKEAHCKSLGAEWFVD 239
Query: 259 S-AKEDAVSKILEYTNGRGVDCVMEAVGAQATWDICQRVIKEGGHLANVGV 308
+ ED V+ I E T+G G V+ A+ + +++ G + VG+
Sbjct: 240 AFGTEDIVAHIREITDG-GAHGVVNFAAAKVPMEKALEYVRKRGTVVFVGL 289
>YMR303c [Q] KOG0023 Alcohol dehydrogenase class V
Length = 348
Score = 66.6 bits (161), Expect = 6e-11
Identities = 69/306 (22%), Positives = 136/306 (43%), Gaps = 22/306 (7%)
Query: 32 KAMVYYGANDIKFEDREQPQILSS-TDAIIKMTHTSICGTDLGIWKGKNPEIEQTAQTKE 90
KA+++Y +N K E ++ P + +I + ++ +C TDL W G P +
Sbjct: 8 KAIIFYESNG-KLEHKDIPVPKPKPNELLINVKYSGVCHTDLHAWHGDWPLPTKLPL--- 63
Query: 91 GSFNGRILGHEGIGIIDEVGDAVHNFKKGDRVIVSCIS-RCGTCENCAKSLYSHCTNGGG 149
+ GHEG G++ +G+ V +K GD + ++ C CE C S+C +
Sbjct: 64 ------VGGHEGAGVVVGMGENVKGWKIGDYAGIKWLNGSCMACEYCELGNESNCPHAD- 116
Query: 150 WILGYMIDGTQAEYVRTPFADTSLYSVPENLSDEAAVMLSDALPTAHEIGVQMGNVKPGD 209
+ GY DG+ EY + +L++ A ++ + T ++ ++ N++ G
Sbjct: 117 -LSGYTHDGSFQEYATADAVQAAHIPQGTDLAEVAPILCAGI--TVYK-ALKSANLRAGH 172
Query: 210 TVAIVGAGPVGMGCVLTSQLYSPSLLIV-VDIDDNRLAMAKEMGSTHTINSAKE-DAVSK 267
AI GA G+G + + ++ +D + + +G I+ KE D VS
Sbjct: 173 WAAISGAAG-GLGSLAVQYAKAMGYRVLGIDGGPGKEELFTSLGGEVFIDFTKEKDIVSA 231
Query: 268 ILEYTNGRGVDCVMEAVGAQATWDICQRVIKEGGHLANVGV-HGKPVNFEIDKLWIKNLT 326
+++ TNG G ++ ++A + R + G + VG+ G + ++ +K+++
Sbjct: 232 VVKATNG-GAHGIINVSVSEAAIEASTRYCRANGTVVLVGLPAGAKCSSDVFNHVVKSIS 290
Query: 327 ITSGLV 332
I V
Sbjct: 291 IVGSYV 296
>YBR145w [Q] KOG0023 Alcohol dehydrogenase class V
Length = 351
Score = 66.6 bits (161), Expect = 6e-11
Identities = 77/326 (23%), Positives = 144/326 (43%), Gaps = 23/326 (7%)
Query: 32 KAMVYYGAND-IKFEDREQPQILSSTDAIIKMTHTSICGTDLGIWKGKNPEIEQTAQTKE 90
KA+V+Y + ++++D P+ + ++ + ++ +C +DL W G P Q K
Sbjct: 11 KAIVFYETDGKLEYKDVTVPEP-KPNEILVHVKYSGVCHSDLHAWHGDWP-----FQLKF 64
Query: 91 GSFNGRILGHEGIGIIDEVGDAVHNFKKGDRVIVSCIS-RCGTCENCAKSLYSHCTNGGG 149
G HEG G++ ++G V +K GD + ++ C +CE C S C G
Sbjct: 65 PLIGG----HEGAGVVVKLGSNVKGWKVGDFAGIKWLNGTCMSCEYCEVGNESQCPYLDG 120
Query: 150 WILGYMIDGTQAEYVRTPFADTSLYSVPENLSDEAAVMLSDALPTAHEIGVQMGNVKPGD 209
G+ DGT EY + NL++ A ++ + T ++ ++ NV PG
Sbjct: 121 --TGFTHDGTFQEYATADAVQAAHIPPNVNLAEVAPILCAGI--TVYK-ALKRANVIPGQ 175
Query: 210 TVAIVGAGPVGMGCVLTSQLYSPSLLIV-VDIDDNRLAMAKEMGSTHTINSAKE-DAVSK 267
V I GA G+G + + ++ +D + + + +++G I+ +E D V
Sbjct: 176 WVTISGACG-GLGSLAIQYALAMGYRVIGIDGGNAKRKLFEQLGGEIFIDFTEEKDIVGA 234
Query: 268 ILEYTNGRGVDCVMEAVGAQATWDICQRVIKEGGHLANVGVHGKP-VNFEIDKLWIKNLT 326
I++ TNG G V+ ++A + R + G + VG+ N ++ +K+++
Sbjct: 235 IIKATNG-GSHGVINVSVSEAAIEASTRYCRPNGTVVLVGMPAHAYCNSDVFNQVVKSIS 293
Query: 327 ITSGLV-NTNTTGMLMKSCCSGKLKS 351
I V N T + G +KS
Sbjct: 294 IVGSCVGNRADTREALDFFARGLIKS 319
>At4g37990 [Q] KOG0023 Alcohol dehydrogenase class V
Length = 359
Score = 66.2 bits (160), Expect = 8e-11
Identities = 54/240 (22%), Positives = 106/240 (43%), Gaps = 13/240 (5%)
Query: 99 GHEGIGIIDEVGDAVHNFKKGDRVIVSC-ISRCGTCENCAKSLYSHC-----TNGGGWIL 152
GHE +G++ EVG V FK G++V V C +S CG+C++C + + ++C T G +
Sbjct: 67 GHEIVGVVTEVGAKVTKFKTGEKVGVGCLVSSCGSCDSCTEGMENYCPKSIQTYGFPYYD 126
Query: 153 GYMIDGTQAEYVRTPFADTSLYSVPENLSDEAAVMLSDALPTAHEIGVQMGNVKPGDTVA 212
+ G ++++ + + +P+NL +AA L A T + G KPG +
Sbjct: 127 NTITYGGYSDHM--VCEEGFVIRIPDNLPLDAAAPLLCAGITVYSPMKYHGLDKPGMHIG 184
Query: 213 IVGAGPVGMGCVLTSQLYSPSLLIVVDIDDNRLAMAKEMGSTHTINSAKEDAVSKILEYT 272
+VG G +G V ++ + ++ + R +G+ + S + +
Sbjct: 185 VVGLGGLGHVGVKFAKAMGTKVTVISTSEKKRDEAINRLGADAFLVSRDPKQIKDAMGTM 244
Query: 273 NGRGVDCVMEAVGAQATWDICQRVIKEGGHLANVGVHGKPVNFEIDKLWIKNLTITSGLV 332
+G +++ V A + ++K G L VG KP+ + L + + ++
Sbjct: 245 DG-----IIDTVSATHSLLPLLGLLKHKGKLVMVGAPEKPLELPVMPLIFERKMVMGSMI 299
>At4g34230 [Q] KOG0023 Alcohol dehydrogenase class V
Length = 357
Score = 66.2 bits (160), Expect = 8e-11
Identities = 70/296 (23%), Positives = 116/296 (38%), Gaps = 19/296 (6%)
Query: 57 DAIIKMTHTSICGTDLGIWKGKNPEIEQTAQTKEGSFNGRILGHEGIGIIDEVGDAVHNF 116
D I++ IC TDL QT S + GHE +G + EVG V F
Sbjct: 36 DVNIRIICCGICHTDL----------HQTKNDLGMSNYPMVPGHEVVGEVVEVGSDVSKF 85
Query: 117 KKGDRVIVSC-ISRCGTCENCAKSLYSHCTNGGGWILGYMIDG--TQAEYVR-TPFADTS 172
GD V V C + CG C C + L +C I+G TQ + + T
Sbjct: 86 TVGDIVGVGCLVGCCGGCSPCERDLEQYCPKKIWSYNDVYINGQPTQGGFAKATVVHQKF 145
Query: 173 LYSVPENLSDEAAVMLSDALPTAHEIGVQMGNVKPGDTVAIVGAGPVGMGCVLTSQLYSP 232
+ +PE ++ E A L A T + G +PG I+G G VG V ++
Sbjct: 146 VVKIPEGMAVEQAAPLLCAGVTVYSPLSHFGLKQPGLRGGILGLGGVGHMGVKIAKAMGH 205
Query: 233 SLLIVVDIDDNRLAMAKEMGSTHTINSAKEDAVSKILEYTNGRGVDCVMEAVGAQATWDI 292
+ ++ + R +++G+ + + + +S++ + +D V++ V +
Sbjct: 206 HVTVISSSNKKREEALQDLGADDYVIGSDQAKMSELAD-----SLDYVIDTVPVHHALEP 260
Query: 293 CQRVIKEGGHLANVGVHGKPVNFEIDKLWIKNLTITSGLVNTNTTGMLMKSCCSGK 348
++K G L +GV P+ F L + IT + + M C K
Sbjct: 261 YLSLLKLDGKLILMGVINNPLQFLTPLLMLGRKVITGSFIGSMKETEEMLEFCKEK 316
>Hs20549232 [Q] KOG0024 Sorbitol dehydrogenase
Length = 240
Score = 65.9 bits (159), Expect = 1e-10
Identities = 51/204 (25%), Positives = 92/204 (45%), Gaps = 18/204 (8%)
Query: 62 MTHTSICGTDLGIWKGKNPEIEQTAQTKEGSF---NGRILGHEGIGIIDEVGDAVHNFKK 118
M ICG+D+ W+ + G+F +LGHE G +++VG +V + K
Sbjct: 1 MHSVGICGSDVHYWE----------YGRIGNFIVKKPMVLGHEASGTVEKVGSSVKHLKP 50
Query: 119 GDRVIVSCISRCGTCENCAKSLYSHCTNGGGWILGYMIDGTQAEYVRTPFADTSLYSVPE 178
GDRV + + E C Y+ + + DG ++ + A Y +P+
Sbjct: 51 GDRVAIESGAPRENDEFCKMGRYN-LSPSIFFCATPPDDGNLCQFYKHNAA--FCYKLPD 107
Query: 179 NLSDEAAVMLSDALPTAHEIGVQMGNVKPGDTVAIVGAGPVGMGCVLTSQLYSPSLLIVV 238
N++ E ++ H + G V G V + GAG +G+ +L ++ + ++V
Sbjct: 108 NVTFEEGALIDPLSVGIH--ACRRGGVTLGHKVLVCGAGAIGVVTLLVAKAMGAAQVVVT 165
Query: 239 DIDDNRLAMAKEMGSTHTINSAKE 262
D+ RL+ AKE+G+ + +KE
Sbjct: 166 DLSATRLSKAKEIGADLVLQISKE 189
>YMR083w [Q] KOG0023 Alcohol dehydrogenase class V
Length = 375
Score = 65.5 bits (158), Expect = 1e-10
Identities = 68/306 (22%), Positives = 136/306 (44%), Gaps = 22/306 (7%)
Query: 32 KAMVYY-GANDIKFEDREQPQILSSTDAIIKMTHTSICGTDLGIWKGKNPEIEQTAQTKE 90
K +++Y + ++D P+ + +I + ++ +C TDL W G P +
Sbjct: 35 KGVIFYENKGKLHYKDIPVPEP-KPNEILINVKYSGVCHTDLHAWHGDWPLPVKLPL--- 90
Query: 91 GSFNGRILGHEGIGIIDEVGDAVHNFKKGDRVIVSCIS-RCGTCENCAKSLYSHCTNGGG 149
+ GHEG G++ ++G V +K GD + ++ C TCE C S+C +
Sbjct: 91 ------VGGHEGAGVVVKLGSNVKGWKVGDLAGIKWLNGSCMTCEFCESGHESNCPDAD- 143
Query: 150 WILGYMIDGTQAEYVRTPFADTSLYSVPENLSDEAAVMLSDALPTAHEIGVQMGNVKPGD 209
+ GY DG+ ++ + +L++ A ++ + T ++ ++ ++K GD
Sbjct: 144 -LSGYTHDGSFQQFATADAIQAAKIQQGTDLAEVAPILCAGV--TVYK-ALKEADLKAGD 199
Query: 210 TVAIVGAGPVGMGCVLTSQLYSPSLLIV-VDIDDNRLAMAKEMGSTHTINSAK-EDAVSK 267
VAI GA G+G + + ++ +D + + + K++G I+ K ++ VS
Sbjct: 200 WVAISGAAG-GLGSLAVQYATAMGYRVLGIDAGEEKEKLFKKLGGEVFIDFTKTKNMVSD 258
Query: 268 ILEYTNGRGVDCVMEAVGAQATWDICQRVIKEGGHLANVGVHGKP-VNFEIDKLWIKNLT 326
I E T G G V+ ++A + ++ G + VG+ V E+ +K++
Sbjct: 259 IQEATKG-GPHGVINVSVSEAAISLSTEYVRPCGTVVLVGLPANAYVKSEVFSHVVKSIN 317
Query: 327 ITSGLV 332
I V
Sbjct: 318 IKGSYV 323
>Hs22052673 [Q] KOG0022 Alcohol dehydrogenase class III
Length = 468
Score = 64.3 bits (155), Expect = 3e-10
Identities = 54/229 (23%), Positives = 98/229 (42%), Gaps = 13/229 (5%)
Query: 151 ILGYMIDGTQAEYVRTPFADTSLYSVPENLSDEAAVMLSDALPTAHEIGVQMGNVKPGDT 210
I YM T +EY T A+ SL + + E +L + T V+ GD+
Sbjct: 15 IYHYMGCSTFSEY--TVVAEVSLAKINPEANHEHVCLLGCGVTTGIGAVHNTAKVQEGDS 72
Query: 211 VAIVGAGPVGMGCVLTSQLYSPSLLIVVDIDDNRLAMAKEMGSTHTINSAKED-AVSKIL 269
VA+ G G +G+ V ++ +IVVD++ ++ A+AKE G+T +N D + +++
Sbjct: 73 VAVFGLGGIGLAVVQAARQAKAGRIIVVDMNPDKFALAKEFGATDFLNPKDYDKPIQQVI 132
Query: 270 EYTNGRGVDCVMEAVGAQATWDICQRVIKEG-GHLANVGVHG-------KPVNFEIDKLW 321
G GVD E +G G G +GV G +P + W
Sbjct: 133 VEMTGWGVDHSFECIGNVNVMRAALESAHRGWGQSVIIGVAGAGQEISTRPFQLVTGRKW 192
Query: 322 IKNLTITSGLVNTNTTGMLMKSCCSGKLKSERLVTHHCNFGEMSGNYNI 370
+ + G+ +++ +GK++ E VTH +++ +++
Sbjct: 193 LG--SAFGGVKGRTQLPGMVEDAMNGKIQLEPFVTHTMGLDQINEAFDL 239
>Hs18583841 [Q] KOG0024 Sorbitol dehydrogenase
Length = 240
Score = 63.5 bits (153), Expect = 5e-10
Identities = 50/204 (24%), Positives = 90/204 (43%), Gaps = 18/204 (8%)
Query: 62 MTHTSICGTDLGIWKGKNPEIEQTAQTKEGSF---NGRILGHEGIGIIDEVGDAVHNFKK 118
M ICG+D+ W+ + G+F +LGHE G +++VG + + K
Sbjct: 1 MHSVGICGSDVHYWE----------YGRIGNFIVKKPMVLGHEASGTVEKVGSSAKHLKP 50
Query: 119 GDRVIVSCISRCGTCENCAKSLYSHCTNGGGWILGYMIDGTQAEYVRTPFADTSLYSVPE 178
GDRV + + E C Y+ + + DG + + A Y +P+
Sbjct: 51 GDRVAIESGAPRENDEFCKMGRYN-LSPSIFFCATPPDDGNLCRFYKHNAA--FCYKLPD 107
Query: 179 NLSDEAAVMLSDALPTAHEIGVQMGNVKPGDTVAIVGAGPVGMGCVLTSQLYSPSLLIVV 238
N++ E ++ H + G V G V + GAG +G+ +L ++ + ++V
Sbjct: 108 NVTFEEGALIDPLSVGIH--ACRRGGVTLGHKVLVCGAGAIGVVTLLVAKAMGAAQVVVT 165
Query: 239 DIDDNRLAMAKEMGSTHTINSAKE 262
D+ RL+ AKE+G+ + +KE
Sbjct: 166 DLSATRLSKAKEIGADLVLQISKE 189
>At4g37970 [Q] KOG0023 Alcohol dehydrogenase class V
Length = 363
Score = 63.5 bits (153), Expect = 5e-10
Identities = 68/300 (22%), Positives = 118/300 (38%), Gaps = 24/300 (8%)
Query: 60 IKMTHTSICGTDLGIWKGKNPEIEQTAQTKEGSFNGRILGHEGIGIIDEVGDAVHNFKKG 119
+K+ + IC +DL K + S + GHE IG + E+G+ V F G
Sbjct: 43 VKVLYCGICHSDLHCLKNE----------WHSSIYPLVPGHEIIGEVSEIGNKVSKFNLG 92
Query: 120 DRVIVSCI-SRCGTCENCAKSLYSHCTNGGGWILGYMIDGT-----QAEYVRTPFADTSL 173
D+V V CI C TCE+C + ++CT G DGT ++++ +
Sbjct: 93 DKVGVGCIVDSCRTCESCREDQENYCTKAIATYNGVHHDGTINYGGYSDHIVVD--ERYA 150
Query: 174 YSVPENLSDEAAVMLSDALPTAHEIGVQMGNVKPGDTVAIVGAGPVGMGCVLTSQLYSPS 233
+P L +A L A + + G P V IVG G +G V ++ +
Sbjct: 151 VKIPHTLPLVSAAPLLCAGISMYSPMKYFGLTGPDKHVGIVGLGGLGHIGVRFAKAFGTK 210
Query: 234 LLIVVDIDDNRLAMAKEMGSTHTINSAKEDAVSKILEYTNGRGVDCVMEAVGAQATWDIC 293
+ +V +G+ + S ED + + +G +++ V A +
Sbjct: 211 VTVVSSTTGKSKDALDTLGADGFLVSTDEDQMKAAMGTMDG-----IIDTVSASHSISPL 265
Query: 294 QRVIKEGGHLANVGVHGKPVNFEIDKLWIKNLTIT-SGLVNTNTTGMLMKSCCSGKLKSE 352
++K G L +G KP + L + +I SG+ T ++ +K+E
Sbjct: 266 IGLLKSNGKLVLLGATEKPFDISAFSLILGRKSIAGSGIGGMQETQEMIDFAAEHGIKAE 325
>YOL086c [Q] KOG0023 Alcohol dehydrogenase class V
Length = 348
Score = 62.4 bits (150), Expect = 1e-09
Identities = 62/281 (22%), Positives = 127/281 (45%), Gaps = 21/281 (7%)
Query: 32 KAMVYYGAND-IKFEDREQPQILSSTDAIIKMTHTSICGTDLGIWKGKNPEIEQTAQTKE 90
K +++Y ++ ++++D P+ + + +I + ++ +C TDL W G P +
Sbjct: 8 KGVIFYESHGKLEYKDIPVPKP-KANELLINVKYSGVCHTDLHAWHGDWPLPVKLPL--- 63
Query: 91 GSFNGRILGHEGIGIIDEVGDAVHNFKKGDRVIVSCIS-RCGTCENCAKSLYSHCTNGGG 149
+ GHEG G++ +G+ V +K GD + ++ C CE C S+C +
Sbjct: 64 ------VGGHEGAGVVVGMGENVKGWKIGDYAGIKWLNGSCMACEYCELGNESNCPHAD- 116
Query: 150 WILGYMIDGTQAEYVRTPFADTSLYSVPENLSDEAAVMLSDALPTAHEIGVQMGNVKPGD 209
+ GY DG+ +Y + +L+ A ++ + T ++ ++ N+ G
Sbjct: 117 -LSGYTHDGSFQQYATADAVQAAHIPQGTDLAQVAPILCAGI--TVYK-ALKSANLMAGH 172
Query: 210 TVAIVGAGPVGMGCVLTSQLYSPSLLIV-VDIDDNRLAMAKEMGSTHTINSAKE-DAVSK 267
VAI GA G+G + + ++ +D + + + + +G I+ KE D V
Sbjct: 173 WVAISGAAG-GLGSLAVQYAKAMGYRVLGIDGGEGKEELFRSIGGEVFIDFTKEKDIVGA 231
Query: 268 ILEYTNGRGVDCVMEAVGAQATWDICQRVIKEGGHLANVGV 308
+L+ T+G G V+ ++A + R ++ G VG+
Sbjct: 232 VLKATDG-GAHGVINVSVSEAAIEASTRYVRANGTTVLVGM 271
>YCR105w [Q] KOG0023 Alcohol dehydrogenase class V
Length = 361
Score = 62.4 bits (150), Expect = 1e-09
Identities = 68/294 (23%), Positives = 123/294 (41%), Gaps = 26/294 (8%)
Query: 50 PQILSSTDAIIKMTHTSICGTDLGIWKGKNPEIEQTAQTKEGSFNGRILGHEGIGIIDEV 109
P+ D +++ ICG+D I G + + +ILGHE IG + +V
Sbjct: 28 PKPFGDHDVDVEIEACGICGSDFHIAVGNWGPVPEN----------QILGHEIIGRVVKV 77
Query: 110 GDAVH-NFKKGDRVIVSCIS-RCGTCENCAKSLYSHCTNGGGWIL------GYMIDGTQA 161
G H K GDRV V + C CE C +CTN + GY+ G A
Sbjct: 78 GSKCHTGVKIGDRVGVGAQALACFECERCKSDNEQYCTNDHVLTMWTPYKDGYISQGGFA 137
Query: 162 EYVRTPFADTSLYSVPENLSDEAAVMLSDALPTAHEIGVQMGNVKPGDTVAIVGAGPVG- 220
+VR + +PEN+ A L T ++ G PG V IVG G +G
Sbjct: 138 SHVR--LHEHFAIQIPENIPSPLAAPLLCGGITVFSPLLRNG-CGPGKRVGIVGIGGIGH 194
Query: 221 MGCVLTSQLYSPSLLIVVDIDDNRLAMAKEMGSTHTINSAKEDAVSKILEYTNGRGVDCV 280
MG +L + + + ++ + ++G+ H I ++ ++ +Y+N + V
Sbjct: 195 MGILLAKAMGAE--VYAFSRGHSKREDSMKLGADHYIAMLEDKGWTE--QYSNALDLLVV 250
Query: 281 MEAVGAQATWDICQRVIKEGGHLANVGVHGKPVNFEIDKLWIKNLTITSGLVNT 334
+ ++ +D +++K GG + ++ + L + ++I+S + +
Sbjct: 251 CSSSLSKVNFDSIVKIMKIGGSIVSIAAPEVNEKLVLKPLGLMGVSISSSAIGS 304
>At3g56460 [CR] KOG1198 Zinc-binding oxidoreductase
Length = 348
Score = 62.0 bits (149), Expect = 1e-09
Identities = 61/235 (25%), Positives = 101/235 (42%), Gaps = 44/235 (18%)
Query: 97 ILGHEGIGIIDEVGDAVHNFKKGDRVIVSCISRCGTCENCAKSLYSHCTNGGGWILGYMI 156
I G + GI+D +G AV F+ GDRV C +
Sbjct: 71 IPGSDYSGIVDAIGPAVTKFRVGDRV-------CSFADL--------------------- 102
Query: 157 DGTQAEYVRTPFADTS-LYSVPENLSDEAAVMLSDALPTAHEIGVQMGNVKPGDTVAIVG 215
G+ A+++ AD S L+ VPE AA L A T+H V + G + ++G
Sbjct: 103 -GSFAQFI---VADQSRLFLVPERCDMVAAAALPVAFGTSHVALVHRARLTSGQVLLVLG 158
Query: 216 A-GPVGMGCVLTSQLYSPSLLIVVDIDDNRLAMAKEMGSTHTINSAKEDAVSKILEYTNG 274
A G VG+ V ++ +++I V ++ + K MG H ++ E+ +S + E+
Sbjct: 159 AAGGVGLAAVQIGKVCG-AIVIAVARGTEKIQLLKSMGVDHVVDLGTENVISSVKEFIKT 217
Query: 275 R---GVDCVMEAVGAQATWDICQRVIKEGGHLANVG-----VHGKPVNFEIDKLW 321
R GVD + + VG + T + +V+K G + +G + P N + K W
Sbjct: 218 RKLKGVDVLYDPVGGKLTKE-SMKVLKWGAQILVIGFASGEIPVIPANIALVKNW 271
>Hs4758912 [CR] KOG1198 Zinc-binding oxidoreductase
Length = 322
Score = 60.5 bits (145), Expect = 4e-09
Identities = 40/139 (28%), Positives = 72/139 (51%), Gaps = 4/139 (2%)
Query: 148 GGWILGYMIDGTQAEYVRTPFADTSLYSVPENLSDEAAVMLSDALPTAHEIGVQMGNVKP 207
G + + G QA+YV P + L +PE L+ A + +A TA ++ +GNV+
Sbjct: 83 GDTAMALLPGGGQAQYVTVP--EGLLMPIPEGLTLTQAAAIPEAWLTAFQLLHLVGNVQA 140
Query: 208 GDTVAI-VGAGPVGMGCVLTSQLYSPSLLIVVDIDDNRLAMAKEMGSTHTINSAKEDAVS 266
GD V I G VG + +++ + ++ +V +L MA+++G+ N KED
Sbjct: 141 GDYVLIHAGLSGVGTAAIQLTRM-AGAIPLVTAGSQKKLQMAEKLGAAAGFNYKKEDFSE 199
Query: 267 KILEYTNGRGVDCVMEAVG 285
L++T G GV+ +++ +G
Sbjct: 200 ATLKFTKGAGVNLILDCIG 218
>Hs13236495 [CR] KOG1198 Zinc-binding oxidoreductase
Length = 329
Score = 60.5 bits (145), Expect = 4e-09
Identities = 52/213 (24%), Positives = 87/213 (40%), Gaps = 33/213 (15%)
Query: 99 GHEGIGIIDEVGDAVHNFKKGDRVIVSCISRCGTCENCAKSLYSHCTNGGGWILGYMIDG 158
G + G+I+ VGD FKKGDRV S I G
Sbjct: 70 GSDVAGVIEAVGDNASAFKKGDRVFTSS----------------------------TISG 101
Query: 159 TQAEYVRTPFADTSLYSVPENLSDEAAVMLSDALPTAHEIGVQMGNVKPGDTVAIVGA-G 217
AEY AD ++Y +PE L + + TA+ + VK G++V + GA G
Sbjct: 102 GYAEYALA--ADHTVYKLPEKLDFKQGAAIGIPYFTAYRALIHSACVKAGESVLVHGASG 159
Query: 218 PVGMGCVLTSQLYSPSLLIVVDIDDNRLAMAKEMGSTHTINSAKEDAVSKILEYTNGRGV 277
VG+ ++ Y +L ++ + + + G+ N + + + KI +Y +G+
Sbjct: 160 GVGLAACQIARAYGLKILGTAGTEEGQ-KIVLQNGAHEVFNHREVNYIDKIKKYVGEKGI 218
Query: 278 DCVMEAVGAQATWDICQRVIKEGGHLANVGVHG 310
D ++E + A ++ GG + VG G
Sbjct: 219 DIIIEML-ANVNLSKDLSLLSHGGRVIVVGSRG 250
>At3g19450 [Q] KOG0023 Alcohol dehydrogenase class V
Length = 365
Score = 59.3 bits (142), Expect = 9e-09
Identities = 69/284 (24%), Positives = 112/284 (39%), Gaps = 32/284 (11%)
Query: 57 DAIIKMTHTSICGTDLGIWKGKNPEIEQTAQTKEGSFNGRILGHEGIGIIDEVGDAVHNF 116
D IK+ IC TD I Q S + GHE +G + EVG V F
Sbjct: 37 DVYIKVICCGICHTD----------IHQIKNDLGMSNYPMVPGHEVVGEVLEVGSDVSKF 86
Query: 117 KKGD----RVIVSCISRCGTCENCAKSLYSHCTNGGGWILGYMIDGTQAEYVRTPFADTS 172
GD V+V C CG+C+ C+ L +C I Y T + + FADT
Sbjct: 87 TVGDVVGVGVVVGC---CGSCKPCSSELEQYCNKR---IWSYNDVYTDGKPTQGGFADTM 140
Query: 173 LYS------VPENLSDEAAVMLSDALPTAHEIGVQMGNVKPGDTVAIVGAGPVGMGCVLT 226
+ + +PE ++ E A L A T + G + G I+G G VG V
Sbjct: 141 IVNQKFVVKIPEGMAVEQAAPLLCAGVTVYSPLSHFGLMASGLKGGILGLGGVGHMGVKI 200
Query: 227 SQLYSPSLLIVVDIDDNRLAMAKEMGSTHTINSAKEDAVSKILEYTNGRGVDCVMEAVGA 286
++ + ++ D + + +G+ + S+ + ++ + +D +++ V
Sbjct: 201 AKAMGHHVTVISSSDKKKEEAIEHLGADDYVVSSDPAEMQRLAD-----SLDYIIDTVPV 255
Query: 287 QATWDICQRVIKEGGHLANVGVHGKPVNFEIDKLWIKNLTITSG 330
D +K G L +GV P+ F + L I + SG
Sbjct: 256 FHPLDPYLACLKLDGKLILMGVINTPLQF-VTPLVILGRKVISG 298
>At1g72680 [Q] KOG0023 Alcohol dehydrogenase class V
Length = 355
Score = 59.3 bits (142), Expect = 9e-09
Identities = 66/306 (21%), Positives = 128/306 (41%), Gaps = 29/306 (9%)
Query: 53 LSSTDAIIKMTHTSICGTDLGIWKGKNPEIEQTAQTKEGSFNGRIL-GHEGIGIIDEVGD 111
+++ D + +TH +C D+ IW ++ + G ++ GHE GI+ +VG
Sbjct: 33 VTTDDVSLTITHCGVCYADV-IW----------SRNQHGDSKYPLVPGHEIAGIVTKVGP 81
Query: 112 AVHNFKKGDRV-IVSCISRCGTCENCAKSLYSHCTNGGGWILGYMIDG--TQAEY-VRTP 167
V FK GD V + + ++ C CE C + +C G G DG T+ Y
Sbjct: 82 NVQRFKVGDHVGVGTYVNSCRECEYCNEGQEVNCAKGVFTFNGIDHDGSVTKGGYSSHIV 141
Query: 168 FADTSLYSVPENLSDEAAVMLSDALPTAHEIGVQMGNVKPGDTVAIVGAGPVGMGCVLTS 227
+ Y +P + E+A L A T + ++ +PG ++ ++G G +G V
Sbjct: 142 VHERYCYKIPVDYPLESAAPLLCAGITVYAPMMRHNMNQPGKSLGVIGLGGLGHMAVKFG 201
Query: 228 QLYSPSLLIVVDIDDNRLAMAKEMGSTHTINSAKEDAVSKILEYTNGRGVDCVMEAVGAQ 287
+ + S+ + + +G+ + + S+ D + K LE + +D +++
Sbjct: 202 KAFGLSVTVFSTSISKKEEALNLLGAENFVISSDHDQM-KALE----KSLDFLVDTASGD 256
Query: 288 ATWDICQRVIKEGGHLANVG----VHGKPVNFEIDKLWIKNLTITSGLVNTNTTGMLMKS 343
+D ++K G VG + P N + + ++T G T T ++
Sbjct: 257 HAFDPYMSLLKIAGTYVLVGFPSEIKISPANLNLGMRMLAG-SVTGG---TKITQQMLDF 312
Query: 344 CCSGKL 349
C + K+
Sbjct: 313 CAAHKI 318
>At4g21580 [CR] KOG1198 Zinc-binding oxidoreductase
Length = 325
Score = 58.9 bits (141), Expect = 1e-08
Identities = 53/190 (27%), Positives = 81/190 (41%), Gaps = 33/190 (17%)
Query: 98 LGHEGIGIIDEVGDAVHNFKKGDRVIVSCISRCGTCENCAKSLYSHCTNGGGWILGYMID 157
LG E G I+ VG V +K GD+V CA +GGG+
Sbjct: 61 LGLECSGTIESVGKGVSRWKVGDQV-------------CA------LLSGGGY------- 94
Query: 158 GTQAEYVRTPFADTSLYSVPENLSDEAAVMLSDALPTAHEIGVQMGNVKPGDTVAIVGAG 217
AE V P ++ +P +S + A + T MG + G++ I G G
Sbjct: 95 ---AEKVSVPAGQ--IFPIPAGISLKDAAAFPEVACTVWSTVFMMGRLSVGESFLIHG-G 148
Query: 218 PVGMGCVLTSQLYSPSLLIVVDI-DDNRLAMAKEMGSTHTINSAKEDAVSKILEYTNGRG 276
G+G + + V D +LA KE+G+ IN ED V+K+ T+G+G
Sbjct: 149 SSGIGTFAIQIAKHLGVRVFVTAGSDEKLAACKELGADVCINYKTEDFVAKVKAETDGKG 208
Query: 277 VDCVMEAVGA 286
VD +++ +GA
Sbjct: 209 VDVILDCIGA 218
>At4g39330 [Q] KOG0023 Alcohol dehydrogenase class V
Length = 360
Score = 57.8 bits (138), Expect = 3e-08
Identities = 62/265 (23%), Positives = 104/265 (38%), Gaps = 27/265 (10%)
Query: 57 DAIIKMTHTSICGTDLGIWKGKNPEIEQTAQTKEG-SFNGRILGHEGIGIIDEVGDAVHN 115
D +K+ +C TDL T + G S+ + GHE +GI +VG V
Sbjct: 39 DVTVKILFCGVCHTDL-----------HTIKNDWGYSYYPVVPGHEIVGIATKVGKNVTK 87
Query: 116 FKKGDRVIVSCIS-RCGTCENCAKSLYSHCTNGGGWILGYMIDGTQ--AEYVRTPFADTS 172
FK+GDRV V IS C +CE+C + L ++C DGT+ Y D
Sbjct: 88 FKEGDRVGVGVISGSCQSCESCDQDLENYCPQMSFTYNAIGSDGTKNYGGYSENIVVDQR 147
Query: 173 -LYSVPENLSDEAAVMLSDALPTAHEIGVQMGNVKPGDTVAIVGAGPVGMGCVLTSQLYS 231
+ PENL ++ L A T + G + G + + G G +G V + +
Sbjct: 148 FVLRFPENLPSDSGAPLLCAGITVYSPMKYYGMTEAGKHLGVAGLGGLGHVAVKIGKAFG 207
Query: 232 PSLLIVVDIDDNRLAMAKEMGSTH---TINSAKEDAVSKILEYTNGRGVDCVMEAVGAQA 288
+ ++ +G+ T + K A ++Y +++ + A
Sbjct: 208 LKVTVISSSSTKAEEAINHLGADSFLVTTDPQKMKAAIGTMDY--------IIDTISAVH 259
Query: 289 TWDICQRVIKEGGHLANVGVHGKPV 313
++K G L +G+ KP+
Sbjct: 260 ALYPLLGLLKVNGKLIALGLPEKPL 284
>At4g37980 [Q] KOG0023 Alcohol dehydrogenase class V
Length = 357
Score = 55.8 bits (133), Expect = 1e-07
Identities = 62/282 (21%), Positives = 112/282 (38%), Gaps = 23/282 (8%)
Query: 57 DAIIKMTHTSICGTDLGIWKGKNPEIEQTAQTKEGSFNGRILGHEGIGIIDEVGDAVHNF 116
D K+ IC TDL + K E T + GHE +G++ EVG V F
Sbjct: 35 DVRFKVLFCGICHTDLSMAKN-----EWGLTTYP-----LVPGHEIVGVVTEVGAKVKKF 84
Query: 117 KKGDRVIVSCIS-RCGTCENCAKSLYSHC-----TNGGGWILGYMIDGTQAEYVRTPFAD 170
GD+V V ++ C +C++C ++C T+G M G ++++ A+
Sbjct: 85 NAGDKVGVGYMAGSCRSCDSCNDGDENYCPKMILTSGAKNFDDTMTHGGYSDHM--VCAE 142
Query: 171 TSLYSVPENLSDEAAVMLSDALPTAHEIGVQMGNVKPGDTVAIVGAGPVGMGCVLTSQLY 230
+ +P+NL + A L A T + G KPG + +VG G +G V ++
Sbjct: 143 DFIIRIPDNLPLDGAAPLLCAGVTVYSPMKYHGLDKPGMHIGVVGLGGLGHVAVKFAKAM 202
Query: 231 SPSLLIVVDIDDNRLAMAKEMGSTHTINSAKEDAVSKILEYTNGRGVDCVMEAVGAQATW 290
+ ++ + R +G+ + S + + +G +++ V A
Sbjct: 203 GTKVTVISTSERKRDEAVTRLGADAFLVSRDPKQMKDAMGTMDG-----IIDTVSATHPL 257
Query: 291 DICQRVIKEGGHLANVGVHGKPVNFEIDKLWIKNLTITSGLV 332
++K G L VG +P+ + L + +V
Sbjct: 258 LPLLGLLKNKGKLVMVGAPAEPLELPVFPLIFGRKMVVGSMV 299
>At2g21730 [Q] KOG0023 Alcohol dehydrogenase class V
Length = 376
Score = 55.5 bits (132), Expect = 1e-07
Identities = 65/304 (21%), Positives = 122/304 (39%), Gaps = 24/304 (7%)
Query: 57 DAIIKMTHTSICGTDLGIWKGKNPEIEQTAQTKEGSFNGRIL-GHEGIGIIDEVGDAVHN 115
D +K+ +C +DL T + G I+ GHE +GI +VG V
Sbjct: 33 DVTVKILFCGVCHSDL-----------HTIKNHWGFSRYPIIPGHEIVGIATKVGKNVTK 81
Query: 116 FKKGDRVIVS-CISRCGTCENCAKSLYSHCTNGGGWILGYMIDGT---QAEYVRTPFAD- 170
FK+GDRV V I C +CE+C + L ++C DGT Q Y D
Sbjct: 82 FKEGDRVGVGVIIGSCQSCESCNQDLENYCPKVVFTYNSRSSDGTSRNQGGYSDVIVVDH 141
Query: 171 TSLYSVPENL-SDEAAVMLSDALPTAHEIGVQMGNVKPGDTVAIVGAGPVGMGCVLTSQL 229
+ S+P+ L SD A +L + + + G + + G G +G V +
Sbjct: 142 RFVLSIPDGLPSDSGAPLLCAGITVYSPMKYYGMTKESGKRLGVNGLGGLGHIAVKIGKA 201
Query: 230 YSPSLLIVVDIDDNRLAMAKEMGSTHTINSAKEDAVSKILEYTNGRGVDCVMEAVGAQAT 289
+ + ++ + +G+ + + + + + +D +++ V A+
Sbjct: 202 FGLRVTVISRSSEKEREAIDRLGADSFLVTTDSQKMKEAV-----GTMDFIIDTVSAEHA 256
Query: 290 WDICQRVIKEGGHLANVGVHGKPVNFEIDKLWI-KNLTITSGLVNTNTTGMLMKSCCSGK 348
++K G L +G+ KP++ I L + + + S + T +++ C K
Sbjct: 257 LLPLFSLLKVNGKLVALGLPEKPLDLPIFSLVLGRKMVGGSQIGGMKETQEMLEFCAKHK 316
Query: 349 LKSE 352
+ S+
Sbjct: 317 IVSD 320
>YMR318c [Q] KOG0023 Alcohol dehydrogenase class V
Length = 360
Score = 55.1 bits (131), Expect = 2e-07
Identities = 67/302 (22%), Positives = 127/302 (41%), Gaps = 26/302 (8%)
Query: 50 PQILSSTDAIIKMTHTSICGTDLGIWKGKNPEIEQTAQTKEGSFNGRILGHEGIGIIDEV 109
P+ D IK+ +CG+D+ G ++ ++GHE +G + ++
Sbjct: 28 PKPFYDHDIDIKIEACGVCGSDIHCAAGHWGNMKMPL----------VVGHEIVGKVVKL 77
Query: 110 GDAVHN-FKKGDRVIVSC-ISRCGTCENCAKSLYSHCTN-----GGGWILGYMIDGTQAE 162
G ++ K G RV V + C C+ C +CT + GY+ G A
Sbjct: 78 GPKSNSGLKVGQRVGVGAQVFSCLECDRCKNDNEPYCTKFVTTYSQPYEDGYVSQGGYAN 137
Query: 163 YVRTPFADTSLYSVPENLSDEAAVMLSDALPTAHEIGVQMGNVKPGDTVAIVGAGPVG-M 221
YVR + + +PEN+ A L T + V+ G PG V IVG G +G M
Sbjct: 138 YVRVH--EHFVVPIPENIPSHLAAPLLCGGLTVYSPLVRNG-CGPGKKVGIVGLGGIGSM 194
Query: 222 GCVLTSQLYSPSLLIVVDIDDNRLAMAKEMGSTHTINSAKEDAVSKILEYTNGRGVDCVM 281
G +++ + + + V+ + A +MG+ H I + +E + +Y + + V
Sbjct: 195 GTLISKAMGAET--YVISRSSRKREDAMKMGADHYIATLEEGDWGE--KYFDTFDLIVVC 250
Query: 282 EAVGAQATWDICQRVIKEGGHLANVGVHGKPVNFEIDKLWIKNLTIT-SGLVNTNTTGML 340
+ ++I + +K GG + ++ + + + +K ++I+ S L + L
Sbjct: 251 ASSLTDIDFNIMPKAMKVGGRIVSISIPEQHEMLSLKPYGLKAVSISYSALGSIKELNQL 310
Query: 341 MK 342
+K
Sbjct: 311 LK 312
>At2g21890 [Q] KOG0023 Alcohol dehydrogenase class V
Length = 375
Score = 55.1 bits (131), Expect = 2e-07
Identities = 65/303 (21%), Positives = 122/303 (39%), Gaps = 23/303 (7%)
Query: 57 DAIIKMTHTSICGTDLGIWKGKNPEIEQTAQTKEGSFNGRIL-GHEGIGIIDEVGDAVHN 115
D +K+ +C +DL T + G I+ GHE +GI +VG V
Sbjct: 33 DVTVKILFCGVCHSDL-----------HTIKNHWGFSRYPIIPGHEIVGIATKVGKNVTK 81
Query: 116 FKKGDRVIVS-CISRCGTCENCAKSLYSHCTNGGGWILGYMIDGT--QAEYVRTPFAD-T 171
FK+GDRV V I C +CE+C + L ++C DGT Q Y D
Sbjct: 82 FKEGDRVGVGVIIGSCQSCESCNQDLENYCPKVVFTYNSRSSDGTRNQGGYSDVIVVDHR 141
Query: 172 SLYSVPENL-SDEAAVMLSDALPTAHEIGVQMGNVKPGDTVAIVGAGPVGMGCVLTSQLY 230
+ S+P+ L SD A +L + + + G + + G G +G V + +
Sbjct: 142 FVLSIPDGLPSDSGAPLLCAGITVYSPMKYYGMTKESGKRLGVNGLGGLGHIAVKIGKAF 201
Query: 231 SPSLLIVVDIDDNRLAMAKEMGSTHTINSAKEDAVSKILEYTNGRGVDCVMEAVGAQATW 290
+ ++ + +G+ + + + + + +D +++ V A+
Sbjct: 202 GLRVTVISRSSEKEREAIDRLGADSFLVTTDSQKMKEAV-----GTMDFIIDTVSAEHAL 256
Query: 291 DICQRVIKEGGHLANVGVHGKPVNFEIDKLWI-KNLTITSGLVNTNTTGMLMKSCCSGKL 349
++K G L +G+ KP++ I L + + + S + T +++ C K+
Sbjct: 257 LPLFSLLKVSGKLVALGLLEKPLDLPIFPLVLGRKMVGGSQIGGMKETQEMLEFCAKHKI 316
Query: 350 KSE 352
S+
Sbjct: 317 VSD 319
>At5g61510 [CR] KOG1197 Predicted quinone oxidoreductase
Length = 324
Score = 51.6 bits (122), Expect = 2e-06
Identities = 51/204 (25%), Positives = 90/204 (44%), Gaps = 21/204 (10%)
Query: 176 VPENLSDEAAVMLSDALPTAHEIGVQMGNVKPGDTVAIVGAGPVGMGCVLTSQLYSPSLL 235
VP ++ A + TA + + V+PG T+ +V A G+G +L +
Sbjct: 109 VPSSIDPIVAASIMLKGMTAQFLLRRCFKVEPGHTI-LVHAAAGGVGSLLCQWANALGAT 167
Query: 236 IVVDIDDN-RLAMAKEMGSTHTINSAKEDAVSKILEYTNGRGVDCVMEAVGAQATWDICQ 294
++ + N + A AKE G H I ED VS++ + T+G+GV+ V ++VG + T+
Sbjct: 168 VIGTVSTNEKAAQAKEDGCHHVIMYKNEDFVSRVNDITSGKGVNVVYDSVG-KDTFKGSL 226
Query: 295 RVIKEGGHLANVG-VHGKPVNFEIDKLWIKNLTIT-----------------SGLVNTNT 336
+K G++ + G G P + L K+L +T +G V N
Sbjct: 227 ACLKSRGYMVSFGQSSGSPDPIPLSDLAPKSLFLTRPSMMHYNETRDELLECAGEVFANV 286
Query: 337 TGMLMKSCCSGKLKSERLVTHHCN 360
T ++K+ + K R+ H +
Sbjct: 287 TSGILKARVNHKYPLSRVADAHAD 310
>Hs22044912 [Q] KOG0022 Alcohol dehydrogenase class III
Length = 165
Score = 50.1 bits (118), Expect = 6e-06
Identities = 43/149 (28%), Positives = 69/149 (45%), Gaps = 9/149 (6%)
Query: 142 SHCTNGGGWILGYMIDGTQAEYVRTPFADTSLYSVPENLSDEAAVMLSDALPTAHEIGVQ 201
S T G IL YM T +EY T AD S+ + + +L + T + V
Sbjct: 6 SRFTCKGKIILHYMGISTFSEY--TVVADISVSKIDPLARLDKVGLLGCGISTGYGPAVN 63
Query: 202 MGNVKPGDTVAIVGAGPVGMGCVLTSQLYSPSLLIVVDIDDNRLAMAKEMGSTHTI---- 257
++PG AI G G G G + ++ S +I VDI+ ++ + AKE+G+ I
Sbjct: 64 TAKLEPGSVCAIFGLGGFGSGVTMGCKVTGASQIIGVDINKDKFSRAKELGAAECISPQD 123
Query: 258 -NSAKEDAVSKILEYTNGRGVDCVMEAVG 285
+ ++ + +I+ T+G GVD E G
Sbjct: 124 FSKPTQEVLIEIMS-TDG-GVDYSFECTG 150
Database: KOG eukaryal database 04/03
Posted date: Apr 14, 2003 1:07 PM
Number of letters in database: 30,389,216
Number of sequences in database: 60,738
Lambda K H
0.318 0.135 0.402
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 22,891,705
Number of Sequences: 60738
Number of extensions: 1003424
Number of successful extensions: 2534
Number of sequences better than 1.0e-05: 67
Number of HSP's better than 0.0 without gapping: 18
Number of HSP's successfully gapped in prelim test: 49
Number of HSP's that attempted gapping in prelim test: 2396
Number of HSP's gapped (non-prelim): 71
length of query: 386
length of database: 30,389,216
effective HSP length: 108
effective length of query: 278
effective length of database: 23,829,512
effective search space: 6624604336
effective search space used: 6624604336
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)