ORF STATUS Function Best COG Functional category Pathways and functional systems
r_klactMIT365 normal C KOG4769 Energy production and conversion Cytochrome c oxidase, subunit I
Only best alignment is shown:
BLASTP 2.2.3 [May-13-2002]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= r_klactMIT365 33733 32030 -568
(568 letters)
Database: KOG eukaryal database 04/03
60,738 sequences; 30,389,216 total letters
Searching..................................................done
Color Key for Alignment Scores: 
Score E
Sequences producing significant alignments: (bits) Value
YMi004 [C] KOG4769 Cytochrome c oxidase subunit I 407 e-113
YMi005_1 [C] KOG4769 Cytochrome c oxidase subunit I 407 e-113
YMi006_1 [C] KOG4769 Cytochrome c oxidase subunit I 376 e-104
AtMi114 [C] KOG4769 Cytochrome c oxidase subunit I 333 5e-91
DmMi003 [C] KOG4769 Cytochrome c oxidase subunit I 303 6e-82
HsMi003 [C] KOG4769 Cytochrome c oxidase subunit I 299 7e-81
SPMi001 [C] KOG4769 Cytochrome c oxidase subunit I 292 1e-78
CEMi002 [C] KOG4769 Cytochrome c oxidase subunit I 269 7e-72
YMi008 [A] KOG4768 Mitochondrial mRNA maturase 119 2e-26
YMi007_1 [C] KOG4769 Cytochrome c oxidase subunit I 113 7e-25
YMi009 [A] KOG4768 Mitochondrial mRNA maturase 97 7e-20
Hs20542158 [C] KOG4769 Cytochrome c oxidase subunit I 53 1e-06
Hs22042472 [C] KOG4664 Cytochrome oxidase subunit III and relate... 52 3e-06
>YMi004 [C] KOG4769 Cytochrome c oxidase subunit I
Length = 534
Score = 407 bits (1047), Expect = e-113
Identities = 201/236 (85%), Positives = 216/236 (91%)
Query: 1 MIERWLYSTNAKDIAVLYFIFAIFCGMAGTAMSLIIRLELAAPGNQVLSGNHQLFNVLVV 60
M++RWLYSTNAKDIAVLYF+ AIF GMAGTAMSLIIRLELAAPG+Q L GN QLFNVLVV
Sbjct: 1 MVQRWLYSTNAKDIAVLYFMLAIFSGMAGTAMSLIIRLELAAPGSQYLHGNSQLFNVLVV 60
Query: 61 GHAVLMIFFLVMPALIGGFGNYMLPLLIGASDMSFARLNNISFWCLPPALVCLVTSTLVE 120
GHAVLMIFFLVMPALIGGFGNY+LPL+IGA+D +F R+NNI+FW LP LVCLVTSTLVE
Sbjct: 61 GHAVLMIFFLVMPALIGGFGNYLLPLMIGATDTAFPRINNIAFWVLPMGLVCLVTSTLVE 120
Query: 121 SGAGTGWTVYPPLSSIQAHSGPSVDLAIFALHLTSISSLLGAINFIVTTLNMRTNGMTMH 180
SGAGTGWTVYPPLSSIQAHSGPSVDLAIFALHLTSISSLLGAINFIVTTLNMRTNGMTMH
Sbjct: 121 SGAGTGWTVYPPLSSIQAHSGPSVDLAIFALHLTSISSLLGAINFIVTTLNMRTNGMTMH 180
Query: 181 RLPLFVWSIFITAFXXXXXXXXXXAGVTMLLLDRNFNTSFFEVAGGGDPVLYQHLF 236
+LPLFVWSIFITAF AG+TMLLLDRNFNTSFFEV+GGGDP+LY+HLF
Sbjct: 181 KLPLFVWSIFITAFLLLLSLPVLSAGITMLLLDRNFNTSFFEVSGGGDPILYEHLF 236
>YMi005_1 [C] KOG4769 Cytochrome c oxidase subunit I
Length = 421
Score = 407 bits (1047), Expect = e-113
Identities = 201/236 (85%), Positives = 216/236 (91%)
Query: 1 MIERWLYSTNAKDIAVLYFIFAIFCGMAGTAMSLIIRLELAAPGNQVLSGNHQLFNVLVV 60
M++RWLYSTNAKDIAVLYF+ AIF GMAGTAMSLIIRLELAAPG+Q L GN QLFNVLVV
Sbjct: 1 MVQRWLYSTNAKDIAVLYFMLAIFSGMAGTAMSLIIRLELAAPGSQYLHGNSQLFNVLVV 60
Query: 61 GHAVLMIFFLVMPALIGGFGNYMLPLLIGASDMSFARLNNISFWCLPPALVCLVTSTLVE 120
GHAVLMIFFLVMPALIGGFGNY+LPL+IGA+D +F R+NNI+FW LP LVCLVTSTLVE
Sbjct: 61 GHAVLMIFFLVMPALIGGFGNYLLPLMIGATDTAFPRINNIAFWVLPMGLVCLVTSTLVE 120
Query: 121 SGAGTGWTVYPPLSSIQAHSGPSVDLAIFALHLTSISSLLGAINFIVTTLNMRTNGMTMH 180
SGAGTGWTVYPPLSSIQAHSGPSVDLAIFALHLTSISSLLGAINFIVTTLNMRTNGMTMH
Sbjct: 121 SGAGTGWTVYPPLSSIQAHSGPSVDLAIFALHLTSISSLLGAINFIVTTLNMRTNGMTMH 180
Query: 181 RLPLFVWSIFITAFXXXXXXXXXXAGVTMLLLDRNFNTSFFEVAGGGDPVLYQHLF 236
+LPLFVWSIFITAF AG+TMLLLDRNFNTSFFEV+GGGDP+LY+HLF
Sbjct: 181 KLPLFVWSIFITAFLLLLSLPVLSAGITMLLLDRNFNTSFFEVSGGGDPILYEHLF 236
>YMi006_1 [C] KOG4769 Cytochrome c oxidase subunit I
Length = 257
Score = 376 bits (965), Expect = e-104
Identities = 189/236 (80%), Positives = 204/236 (86%), Gaps = 12/236 (5%)
Query: 1 MIERWLYSTNAKDIAVLYFIFAIFCGMAGTAMSLIIRLELAAPGNQVLSGNHQLFNVLVV 60
M++RWLYSTNAKDIAVLYF+ AIF GMAGTAMSLIIRLELAAPG+Q L GN QLFNVLV
Sbjct: 1 MVQRWLYSTNAKDIAVLYFMLAIFSGMAGTAMSLIIRLELAAPGSQYLHGNSQLFNVLV- 59
Query: 61 GHAVLMIFFLVMPALIGGFGNYMLPLLIGASDMSFARLNNISFWCLPPALVCLVTSTLVE 120
MPALIGGFGNY+LPL+IGA+D +F R+NNI+FW LP LVCLVTSTLVE
Sbjct: 60 -----------MPALIGGFGNYLLPLMIGATDTAFPRINNIAFWVLPMGLVCLVTSTLVE 108
Query: 121 SGAGTGWTVYPPLSSIQAHSGPSVDLAIFALHLTSISSLLGAINFIVTTLNMRTNGMTMH 180
SGAGTGWTVYPPLSSIQAHSGPSVDLAIFALHLTSISSLLGAINFIVTTLNMRTNGMTMH
Sbjct: 109 SGAGTGWTVYPPLSSIQAHSGPSVDLAIFALHLTSISSLLGAINFIVTTLNMRTNGMTMH 168
Query: 181 RLPLFVWSIFITAFXXXXXXXXXXAGVTMLLLDRNFNTSFFEVAGGGDPVLYQHLF 236
+LPLFVWSIFITAF AG+TMLLLDRNFNTSFFEV+GGGDP+LY+HLF
Sbjct: 169 KLPLFVWSIFITAFLLLLSLPVLSAGITMLLLDRNFNTSFFEVSGGGDPILYEHLF 224
>AtMi114 [C] KOG4769 Cytochrome c oxidase subunit I
Length = 527
Score = 333 bits (853), Expect = 5e-91
Identities = 154/233 (66%), Positives = 187/233 (80%)
Query: 4 RWLYSTNAKDIAVLYFIFAIFCGMAGTAMSLIIRLELAAPGNQVLSGNHQLFNVLVVGHA 63
RWL+STN KDI LYFIF G+ GT S++IR+ELA PG+Q+L GNHQL+NVL+ HA
Sbjct: 6 RWLFSTNHKDIGTLYFIFGAIAGVMGTCFSVLIRMELARPGDQILGGNHQLYNVLITAHA 65
Query: 64 VLMIFFLVMPALIGGFGNYMLPLLIGASDMSFARLNNISFWCLPPALVCLVTSTLVESGA 123
LMIFF+VMPA+IGGFGN+ +P+LIGA DM+F RLNNISFW LPP+L+ L++S LVE G+
Sbjct: 66 FLMIFFMVMPAMIGGFGNWFVPILIGAPDMAFPRLNNISFWLLPPSLLLLLSSALVEVGS 125
Query: 124 GTGWTVYPPLSSIQAHSGPSVDLAIFALHLTSISSLLGAINFIVTTLNMRTNGMTMHRLP 183
GTGWTVYPPLS I +HSG +VDLAIF+LHL+ +SS+LG+INFI T NMR GMTMHRLP
Sbjct: 126 GTGWTVYPPLSGITSHSGGAVDLAIFSLHLSGVSSILGSINFITTIFNMRGPGMTMHRLP 185
Query: 184 LFVWSIFITAFXXXXXXXXXXAGVTMLLLDRNFNTSFFEVAGGGDPVLYQHLF 236
LFVWS+ +TAF +TMLL DRNFNT+FF+ AGGGDP+LYQHLF
Sbjct: 186 LFVWSVLVTAFLLLLSLPVLAGAITMLLTDRNFNTTFFDPAGGGDPILYQHLF 238
>DmMi003 [C] KOG4769 Cytochrome c oxidase subunit I
Length = 511
Score = 303 bits (775), Expect = 6e-82
Identities = 141/233 (60%), Positives = 181/233 (77%), Gaps = 2/233 (0%)
Query: 4 RWLYSTNAKDIAVLYFIFAIFCGMAGTAMSLIIRLELAAPGNQVLSGNHQLFNVLVVGHA 63
+WL+STN KDI LYFIF + GM GT++S++IR EL PG L G+ Q++NV+V HA
Sbjct: 3 QWLFSTNHKDIGTLYFIFGAWAGMVGTSLSILIRAELGHPG--ALIGDDQIYNVIVTAHA 60
Query: 64 VLMIFFLVMPALIGGFGNYMLPLLIGASDMSFARLNNISFWCLPPALVCLVTSTLVESGA 123
+MIFF+VMP +IGGFGN+++PL++GA DM+F R+NN+SFW LPPAL L+ S++VE+GA
Sbjct: 61 FIMIFFMVMPIMIGGFGNWLVPLMLGAPDMAFPRMNNMSFWLLPPALSLLLVSSMVENGA 120
Query: 124 GTGWTVYPPLSSIQAHSGPSVDLAIFALHLTSISSLLGAINFIVTTLNMRTNGMTMHRLP 183
GTGWTVYPPLS+ AH G SVDLAIF+LHL ISS+LGA+NFI T +NMR+ G+++ R+P
Sbjct: 121 GTGWTVYPPLSAGIAHGGASVDLAIFSLHLAGISSILGAVNFITTVINMRSTGISLDRMP 180
Query: 184 LFVWSIFITAFXXXXXXXXXXAGVTMLLLDRNFNTSFFEVAGGGDPVLYQHLF 236
LFVWS+ ITA +TMLL DRN NTSFF+ AGGGDP+LYQHLF
Sbjct: 181 LFVWSVVITALLLLLSLPVLAGAITMLLTDRNLNTSFFDPAGGGDPILYQHLF 233
>HsMi003 [C] KOG4769 Cytochrome c oxidase subunit I
Length = 513
Score = 299 bits (766), Expect = 7e-81
Identities = 139/234 (59%), Positives = 178/234 (75%), Gaps = 2/234 (0%)
Query: 3 ERWLYSTNAKDIAVLYFIFAIFCGMAGTAMSLIIRLELAAPGNQVLSGNHQLFNVLVVGH 62
+RWL+STN KDI LY +F + G+ GTA+SL+IR EL PGN L GN ++NV+V H
Sbjct: 4 DRWLFSTNHKDIGTLYLLFGAWAGVLGTALSLLIRAELGQPGN--LLGNDHIYNVIVTAH 61
Query: 63 AVLMIFFLVMPALIGGFGNYMLPLLIGASDMSFARLNNISFWCLPPALVCLVTSTLVESG 122
A +MIFF+VMP +IGGFGN+++PL+IGA DM+F R+NN+SFW LPP+L+ L+ S +VE+G
Sbjct: 62 AFVMIFFMVMPIMIGGFGNWLVPLMIGAPDMAFPRMNNMSFWLLPPSLLLLLASAMVEAG 121
Query: 123 AGTGWTVYPPLSSIQAHSGPSVDLAIFALHLTSISSLLGAINFIVTTLNMRTNGMTMHRL 182
AGTGWTVYPPL+ +H G SVDL IF+LHL +SS+LGAINFI T +NM+ MT ++
Sbjct: 122 AGTGWTVYPPLAGNYSHPGASVDLTIFSLHLAGVSSILGAINFITTIINMKPPAMTQYQT 181
Query: 183 PLFVWSIFITAFXXXXXXXXXXAGVTMLLLDRNFNTSFFEVAGGGDPVLYQHLF 236
PLFVWS+ ITA AG+TMLL DRN NT+FF+ AGGGDP+LYQHLF
Sbjct: 182 PLFVWSVLITAVLLLLSLPVLAAGITMLLTDRNLNTTFFDPAGGGDPILYQHLF 235
>SPMi001 [C] KOG4769 Cytochrome c oxidase subunit I
Length = 537
Score = 292 bits (747), Expect = 1e-78
Identities = 132/235 (56%), Positives = 175/235 (74%)
Query: 2 IERWLYSTNAKDIAVLYFIFAIFCGMAGTAMSLIIRLELAAPGNQVLSGNHQLFNVLVVG 61
+ RW++STNAKDIA+LY +F + G+ G+ S IIR+EL+APG+Q LSGN QL+NV +
Sbjct: 8 VNRWIFSTNAKDIAILYLLFGLVSGIIGSVFSFIIRMELSAPGSQFLSGNGQLYNVAISA 67
Query: 62 HAVLMIFFLVMPALIGGFGNYMLPLLIGASDMSFARLNNISFWCLPPALVCLVTSTLVES 121
H +LMIFF ++PAL G FGNY++PL+IGA D+++ R+NN +FW LPPAL+ L+ S L E
Sbjct: 68 HGILMIFFFIIPALFGAFGNYLVPLMIGAPDVAYPRVNNFTFWLLPPALMLLLISALTEE 127
Query: 122 GAGTGWTVYPPLSSIQAHSGPSVDLAIFALHLTSISSLLGAINFIVTTLNMRTNGMTMHR 181
G G GWTVYPPLSSI +HSGP++DLAI +L LT ISS LG++N I T +NMR G+++++
Sbjct: 128 GPGGGWTVYPPLSSITSHSGPAIDLAILSLQLTGISSTLGSVNLIATMINMRAPGLSLYQ 187
Query: 182 LPLFVWSIFITAFXXXXXXXXXXAGVTMLLLDRNFNTSFFEVAGGGDPVLYQHLF 236
+PLF W+I IT+ G+ ML DRN NTSF+ GGGDPVLYQHLF
Sbjct: 188 MPLFAWAIMITSILLLLTLPVLAGGLFMLFSDRNLNTSFYAPEGGGDPVLYQHLF 242
>CEMi002 [C] KOG4769 Cytochrome c oxidase subunit I
Length = 525
Score = 269 bits (688), Expect = 7e-72
Identities = 125/232 (53%), Positives = 170/232 (72%), Gaps = 3/232 (1%)
Query: 5 WLYSTNAKDIAVLYFIFAIFCGMAGTAMSLIIRLELAAPGNQVLSGNHQLFNVLVVGHAV 64
WL S+N KDI LYFIF ++ GM GT+ SL+IRLELA PG N QL+N ++ HA+
Sbjct: 14 WLESSNHKDIGTLYFIFGLWSGMVGTSFSLLIRLELAKPG--FFLSNGQLYNSVITAHAI 71
Query: 65 LMIFFLVMPALIGGFGNYMLPLLIGASDMSFARLNNISFWCLPPALVCLVTSTLVESGAG 124
LMIFF+VMP +IGGFGN++LPL++GA DMSF RLNN+SFW LP +++ ++ + V+ G G
Sbjct: 72 LMIFFMVMPTMIGGFGNWLLPLMLGAPDMSFPRLNNLSFWLLPTSMLLILDACFVDMGCG 131
Query: 125 TGWTVYPPLSSIQAHSGPSVDLAIFALHLTSISSLLGAINFIVTTLNMRTNGMTMHRLPL 184
T WTVYPPLS++ H G SVDLAIF+LH +SS+LG INF+ TT N+R++ +++ + L
Sbjct: 132 TSWTVYPPLSTM-GHPGSSVDLAIFSLHAAGLSSILGGINFMCTTKNLRSSSISLEHMTL 190
Query: 185 FVWSIFITAFXXXXXXXXXXAGVTMLLLDRNFNTSFFEVAGGGDPVLYQHLF 236
FVW++F+T F +TMLL DRN NTSFF+ + GG+P++YQHLF
Sbjct: 191 FVWTVFVTVFLLVLSLPVLAGAITMLLTDRNLNTSFFDPSTGGNPLIYQHLF 242
>YMi008 [A] KOG4768 Mitochondrial mRNA maturase
Length = 854
Score = 119 bits (297), Expect = 2e-26
Identities = 59/68 (86%), Positives = 63/68 (91%)
Query: 1 MIERWLYSTNAKDIAVLYFIFAIFCGMAGTAMSLIIRLELAAPGNQVLSGNHQLFNVLVV 60
M++RWLYSTNAKDIAVLYF+ AIF GMAGTAMSLIIRLELAAPG+Q L GN QLFNVLVV
Sbjct: 1 MVQRWLYSTNAKDIAVLYFMLAIFSGMAGTAMSLIIRLELAAPGSQYLHGNSQLFNVLVV 60
Query: 61 GHAVLMIF 68
GHAVLMIF
Sbjct: 61 GHAVLMIF 68
>YMi007_1 [C] KOG4769 Cytochrome c oxidase subunit I
Length = 69
Score = 113 bits (283), Expect = 7e-25
Identities = 60/81 (74%), Positives = 64/81 (78%), Gaps = 12/81 (14%)
Query: 1 MIERWLYSTNAKDIAVLYFIFAIFCGMAGTAMSLIIRLELAAPGNQVLSGNHQLFNVLVV 60
M++RWLYSTNAKDIAVLYF+ AIF GMAGTAMSLIIRLELAAPG+Q L GN QLFNV
Sbjct: 1 MVQRWLYSTNAKDIAVLYFMLAIFSGMAGTAMSLIIRLELAAPGSQYLHGNSQLFNV--- 57
Query: 61 GHAVLMIFFLVMPALIGGFGN 81
LVMPALIGGFGN
Sbjct: 58 ---------LVMPALIGGFGN 69
>YMi009 [A] KOG4768 Mitochondrial mRNA maturase
Length = 834
Score = 97.1 bits (240), Expect = 7e-20
Identities = 47/56 (83%), Positives = 51/56 (90%)
Query: 1 MIERWLYSTNAKDIAVLYFIFAIFCGMAGTAMSLIIRLELAAPGNQVLSGNHQLFN 56
M++RWLYSTNAKDIAVLYF+ AIF GMAGTAMSLIIRLELAAPG+Q L GN QLFN
Sbjct: 1 MVQRWLYSTNAKDIAVLYFMLAIFSGMAGTAMSLIIRLELAAPGSQYLHGNSQLFN 56
>Hs20542158 [C] KOG4769 Cytochrome c oxidase subunit I
Length = 105
Score = 53.1 bits (126), Expect = 1e-06
Identities = 26/52 (50%), Positives = 34/52 (65%)
Query: 119 VESGAGTGWTVYPPLSSIQAHSGPSVDLAIFALHLTSISSLLGAINFIVTTL 170
VE+GAGT WTVYP L+ +H+G SVDL I +LHL L A+ I+ T+
Sbjct: 54 VEAGAGTRWTVYPSLAGNPSHAGASVDLIIISLHLAGPFISLTAVMLIIFTI 105
>Hs22042472 [C] KOG4664 Cytochrome oxidase subunit III and related proteins
Length = 144
Score = 51.6 bits (122), Expect = 3e-06
Identities = 51/150 (34%), Positives = 73/150 (48%), Gaps = 22/150 (14%)
Query: 31 AMSLIIRLELAAPGNQVLSGNHQLFNVLVVGHAVLMIFFLVMPALIGGFGNYMLPL--LI 88
A+SL+IR EL G L G++Q++NV+V ++IFF+++P + GFGN P L
Sbjct: 2 ALSLLIRAELGQTGT--LPGHYQIYNVIVTADTFVIIFFILIPIINEGFGNCPAPTPELG 59
Query: 89 GASDMSFARLNNISFWCLPPALV---CLVTSTLVESGAGTGWTVYPPLSSIQAHSGP--- 142
G + +IS PP+L+ L TS L+ SG W S I+ S P
Sbjct: 60 GCWPPT-----SIS----PPSLLEVPFLNTSVLLASGVSITWA---HQSLIEEKSSPYEC 107
Query: 143 SVDLAIFALHLTSISSLLGAINFIVTTLNM 172
DL A SI L AI F++ L +
Sbjct: 108 GFDLIGSACLSFSIKCFLVAITFLLFDLEI 137
Database: KOG eukaryal database 04/03
Posted date: Apr 14, 2003 1:07 PM
Number of letters in database: 30,389,216
Number of sequences in database: 60,738
Lambda K H
0.325 0.141 0.432
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 33,972,237
Number of Sequences: 60738
Number of extensions: 1480198
Number of successful extensions: 4360
Number of sequences better than 1.0e-05: 13
Number of HSP's better than 0.0 without gapping: 12
Number of HSP's successfully gapped in prelim test: 1
Number of HSP's that attempted gapping in prelim test: 4341
Number of HSP's gapped (non-prelim): 13
length of query: 568
length of database: 30,389,216
effective HSP length: 112
effective length of query: 456
effective length of database: 23,586,560
effective search space: 10755471360
effective search space used: 10755471360
T: 11
A: 40
X1: 15 ( 7.0 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 40 (21.6 bits)