ORF STATUS Function Best COG Functional category Pathways and functional systems
r_klactV0101 good Z KOG1735 Cytoskeleton Actin depolymerizing factor
Only best alignment is shown:
BLASTP 2.2.3 [May-13-2002]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= r_klactV0101 Highly similar to YLL050c SP|Q03048 COF1 cofilin,
actin binding and severing protein singleton [INTRON]
(131 letters)
Database: KOG eukaryal database 04/03
60,738 sequences; 30,389,216 total letters
Searching..................................................done
Color Key for Alignment Scores: 
Score E
Sequences producing significant alignments: (bits) Value
YLL050c [Z] KOG1735 Actin depolymerizing factor 231 2e-61
SPAC20G4.06c [Z] KOG1735 Actin depolymerizing factor 169 1e-42
At2g31200 [Z] KOG1735 Actin depolymerizing factor 108 1e-24
At5g52360 [Z] KOG1735 Actin depolymerizing factor 103 5e-23
At1g01750 [Z] KOG1735 Actin depolymerizing factor 103 6e-23
At4g00680 [Z] KOG1735 Actin depolymerizing factor 102 2e-22
At3g46000 [Z] KOG1735 Actin depolymerizing factor 101 3e-22
At4g25590 [Z] KOG1735 Actin depolymerizing factor 100 5e-22
At4g34970 [Z] KOG1735 Actin depolymerizing factor 100 9e-22
At3g46010 [Z] KOG1735 Actin depolymerizing factor 97 6e-21
At5g59890 [Z] KOG1735 Actin depolymerizing factor 97 7e-21
Hs14719392 [Z] KOG1735 Actin depolymerizing factor 94 4e-20
Hs5031635 [Z] KOG1735 Actin depolymerizing factor 94 5e-20
At5g59880 [Z] KOG1735 Actin depolymerizing factor 94 6e-20
At2g16700 [Z] KOG1735 Actin depolymerizing factor 92 2e-19
7291724 [Z] KOG1735 Actin depolymerizing factor 92 2e-19
Hs22042272 [Z] KOG1735 Actin depolymerizing factor 86 2e-17
At3g45990 [Z] KOG1735 Actin depolymerizing factor 85 2e-17
Hs5802966 [Z] KOG1735 Actin depolymerizing factor 82 2e-16
CE20547 [Z] KOG1735 Actin depolymerizing factor 71 3e-13
Hs22057868 [Z] KOG1735 Actin depolymerizing factor 63 1e-10
7293502 [Z] KOG1735 Actin depolymerizing factor 62 2e-10
Hs17439599 [Z] KOG1735 Actin depolymerizing factor 62 3e-10
CE20548 [Z] KOG1735 Actin depolymerizing factor 60 1e-09
CE20549 [Z] KOG1735 Actin depolymerizing factor 57 5e-09
Hs17435363 [Z] KOG1735 Actin depolymerizing factor 49 1e-06
Hs17433952 [Z] KOG1735 Actin depolymerizing factor 47 5e-06
Hs6005846 [W] KOG1747 Protein tyrosine kinase 9/actin monomer-bi... 47 9e-06
7299845 [W] KOG1747 Protein tyrosine kinase 9/actin monomer-bind... 46 1e-05
Hs22044643 [Z] KOG1735 Actin depolymerizing factor 45 2e-05
Hs4506275 [W] KOG1747 Protein tyrosine kinase 9/actin monomer-bi... 42 2e-04
SPCC126.06 [W] KOG1747 Protein tyrosine kinase 9/actin monomer-b... 40 0.001
YCR088w [Z] KOG3655 Drebrins and related actin binding proteins 36 0.015
YGR080w [W] KOG1747 Protein tyrosine kinase 9/actin monomer-bind... 35 0.026
Hs4758442 [W] KOG1736 Glia maturation factor beta 33 0.075
Hs18571222 [Z] KOG1735 Actin depolymerizing factor 33 0.098
Hs20561421 [Z] KOG3655 Drebrins and related actin binding proteins 32 0.17
Hs22057765 [Z] KOG1735 Actin depolymerizing factor 32 0.29
SPAC17H9.11 [W] KOG1736 Glia maturation factor beta 30 1.1
Hs4758440 [W] KOG1736 Glia maturation factor beta 30 1.1
7293631 [OR] KOG0010 Ubiquitin-like protein 30 1.1
SPBC646.03 [J] KOG1211 Amidases 29 1.9
SPAC4F10.21 [R] KOG1128 Uncharacterized conserved protein contai... 28 2.4
HsM7661718 [Z] KOG3655 Drebrins and related actin binding proteins 28 2.4
Hs21361670 [Z] KOG3655 Drebrins and related actin binding proteins 28 2.4
7293118 [R] KOG1721 FOG: Zn-finger 28 2.4
SPCC16C4.07 [R] KOG0118 FOG: RRM domain 28 3.2
Hs20127501 [A] KOG2560 RNA splicing factor - Slu7p 28 3.2
CE26678 [L] KOG0221 Mismatch repair ATPase MSH5 (MutS family) 28 3.2
At1g67250 [O] KOG3061 Proteasome maturation factor 28 3.2
At5g38650 [O] KOG3061 Proteasome maturation factor 28 4.1
At4g25180 [K] KOG3122 DNA-directed RNA polymerase III subunit 28 4.1
7296270 [T] KOG1997 PH domain-containing protein 28 4.1
Hs20544189_1 [TW] KOG1225 Teneurin-1 and related extracellular m... 28 4.1
CE23294 [KL] KOG4439 RNA polymerase II transcription termination... 27 7.0
YOR326w [Z] KOG0160 Myosin class V heavy chain 27 9.2
Hs7661700 [T] KOG4225 Sorbin and SH3 domain-containing protein 27 9.2
CE09014 [T] KOG0789 Protein tyrosine phosphatase 27 9.2
7303332 [S] KOG3528 FOG: PDZ domain 27 9.2
>YLL050c [Z] KOG1735 Actin depolymerizing factor
Length = 143
Score = 231 bits (589), Expect = 2e-61
Identities = 109/131 (83%), Positives = 122/131 (92%)
Query: 1 MNAFNDLKLGKKYKFILYALNDSKTEIIVKETSAEQDYDKFLEQLPENDCLYAVYDFEYE 60
+ AFNDLKLGKKYKFIL+ LND+KTEI+VKETS + YD FLE+LPENDCLYA+YDFEYE
Sbjct: 13 LTAFNDLKLGKKYKFILFGLNDAKTEIVVKETSTDPSYDAFLEKLPENDCLYAIYDFEYE 72
Query: 61 LGNNEGKRSKIVFFTWSPDTAPVRSKMVYASSKDALRRALNGVSSDIQGTDFSEVAYESV 120
+ NEGKRSKIVFFTWSPDTAPVRSKMVYASSKDALRRALNGVS+D+QGTDFSEV+Y+SV
Sbjct: 73 INGNEGKRSKIVFFTWSPDTAPVRSKMVYASSKDALRRALNGVSTDVQGTDFSEVSYDSV 132
Query: 121 LEKVSRAAGSH 131
LE+VSR AGSH
Sbjct: 133 LERVSRGAGSH 143
>SPAC20G4.06c [Z] KOG1735 Actin depolymerizing factor
Length = 137
Score = 169 bits (427), Expect = 1e-42
Identities = 76/126 (60%), Positives = 103/126 (81%), Gaps = 2/126 (1%)
Query: 1 MNAFNDLKLGKKYKFILYALNDSKTEIIVKETSAEQDYDKFLEQLPENDCLYAVYDFEYE 60
+ AF +LKLGK +++++ +ND+KTEI+V++ S ++D+D FL LPE DC YA+YDFE+
Sbjct: 13 LEAFQELKLGKSLRYVVFKMNDTKTEIVVEKKSTDKDFDTFLGDLPEKDCRYAIYDFEFN 72
Query: 61 LGNNEGKRSKIVFFTWSPDTAPVRSKMVYASSKDALRRALNGVSSDIQGTDFSEVAYESV 120
LG EG R+KI+F +WSPD AP++SKMVY+SSKD LRRA G+ +DIQ TDFSEVAYE+V
Sbjct: 73 LG--EGVRNKIIFISWSPDVAPIKSKMVYSSSKDTLRRAFTGIGTDIQATDFSEVAYETV 130
Query: 121 LEKVSR 126
LEKV+R
Sbjct: 131 LEKVTR 136
>At2g31200 [Z] KOG1735 Actin depolymerizing factor
Length = 132
Score = 108 bits (271), Expect = 1e-24
Identities = 51/123 (41%), Positives = 86/123 (69%), Gaps = 2/123 (1%)
Query: 4 FNDLKLGKKYKFILYALNDSKTEIIVKET-SAEQDYDKFLEQLPENDCLYAVYDFEYELG 62
F +L+ K ++++++ +++SK E++V++T + + YD FL LP+NDC YAVYDF++
Sbjct: 11 FLELQRKKTHRYVVFKIDESKKEVVVEKTGNPTESYDDFLASLPDNDCRYAVYDFDFVTS 70
Query: 63 NNEGKRSKIVFFTWSPDTAPVRSKMVYASSKDALRRALNGVSSDIQGTDFSEVAYESVLE 122
N ++SKI FF WSP T+ +R+K++Y++SKD L R L G+ +IQ TD +EV E + E
Sbjct: 71 EN-CQKSKIFFFAWSPSTSGIRAKVLYSTSKDQLSRELQGIHYEIQATDPTEVDLEVLRE 129
Query: 123 KVS 125
+ +
Sbjct: 130 RAN 132
>At5g52360 [Z] KOG1735 Actin depolymerizing factor
Length = 130
Score = 103 bits (258), Expect = 5e-23
Identities = 51/117 (43%), Positives = 77/117 (65%), Gaps = 2/117 (1%)
Query: 4 FNDLKLGKKYKFILYALNDSKTEIIVKETSAEQDYDKFLEQLPENDCLYAVYDFEYELGN 63
F +LK + Y+FI++ + D + ++ K S +++YD F LP N+C YAVYDF++
Sbjct: 11 FLELKAKRNYRFIIFRI-DGQQVVVEKLGSPQENYDDFTNYLPPNECRYAVYDFDFTTAE 69
Query: 64 NEGKRSKIVFFTWSPDTAPVRSKMVYASSKDALRRALNGVSSDIQGTDFSEVAYESV 120
N K SKI F WSPD++ VR KMVYASSKD +R L+G+ ++Q TD SE++ + +
Sbjct: 70 NIQK-SKIFFIAWSPDSSRVRMKMVYASSKDRFKRELDGIQVELQATDPSEMSLDII 125
>At1g01750 [Z] KOG1735 Actin depolymerizing factor
Length = 140
Score = 103 bits (257), Expect = 6e-23
Identities = 48/123 (39%), Positives = 84/123 (68%), Gaps = 2/123 (1%)
Query: 4 FNDLKLGKKYKFILYALNDSKTEIIV-KETSAEQDYDKFLEQLPENDCLYAVYDFEYELG 62
F +LK + Y+FI++ +++ ++++ K + E+ Y+ F +PE++C YAVYD+++
Sbjct: 18 FLELKAKRNYRFIVFKIDEKAQQVMIDKLGNPEETYEDFTRSIPEDECRYAVYDYDFTTP 77
Query: 63 NNEGKRSKIVFFTWSPDTAPVRSKMVYASSKDALRRALNGVSSDIQGTDFSEVAYESVLE 122
N ++SKI F WSPDT+ VRSKM+YASSKD +R L+G+ ++Q TD SE++ + +
Sbjct: 78 EN-CQKSKIFFIAWSPDTSRVRSKMLYASSKDRFKRELDGIQVELQATDPSEMSLDIIKG 136
Query: 123 KVS 125
+V+
Sbjct: 137 RVN 139
>At4g00680 [Z] KOG1735 Actin depolymerizing factor
Length = 133
Score = 102 bits (253), Expect = 2e-22
Identities = 48/118 (40%), Positives = 80/118 (67%), Gaps = 2/118 (1%)
Query: 4 FNDLKLGKKYKFILYALNDSKTEI-IVKETSAEQDYDKFLEQLPENDCLYAVYDFEYELG 62
F +LK + Y+FI++ +++ ++ I K + E+ YD F +P+++C YAVYDF++
Sbjct: 11 FLELKAKRTYRFIVFKIDEKAQQVQIEKLGNPEETYDDFTSSIPDDECRYAVYDFDFTTE 70
Query: 63 NNEGKRSKIVFFTWSPDTAPVRSKMVYASSKDALRRALNGVSSDIQGTDFSEVAYESV 120
+N ++SKI F WSPDT+ VRSKM+YASSKD +R + G+ ++Q TD SE++ + +
Sbjct: 71 DN-CQKSKIFFIAWSPDTSRVRSKMLYASSKDRFKREMEGIQVELQATDPSEMSLDII 127
>At3g46000 [Z] KOG1735 Actin depolymerizing factor
Length = 130
Score = 101 bits (251), Expect = 3e-22
Identities = 50/115 (43%), Positives = 72/115 (62%), Gaps = 2/115 (1%)
Query: 4 FNDLKLGKKYKFILYALNDSKTEIIVKETSAEQDYDKFLEQLPENDCLYAVYDFEYELGN 63
F +LK + ++ I+Y + D K I+ K EQ YD F LP +DC Y +YDF++
Sbjct: 11 FMELKAKRTFRTIVYKIED-KQVIVEKLGEPEQSYDDFAASLPADDCRYCIYDFDFVTAE 69
Query: 64 NEGKRSKIVFFTWSPDTAPVRSKMVYASSKDALRRALNGVSSDIQGTDFSEVAYE 118
N ++SKI F WSPDTA VR KM+YASSKD +R L+G+ ++Q TD +E+ +
Sbjct: 70 N-CQKSKIFFIAWSPDTAKVRDKMIYASSKDRFKRELDGIQVELQATDPTEMGLD 123
>At4g25590 [Z] KOG1735 Actin depolymerizing factor
Length = 130
Score = 100 bits (249), Expect = 5e-22
Identities = 48/117 (41%), Positives = 78/117 (66%), Gaps = 2/117 (1%)
Query: 4 FNDLKLGKKYKFILYALNDSKTEIIVKETSAEQDYDKFLEQLPENDCLYAVYDFEYELGN 63
F +LK + Y+FI++ + D + ++ K + ++ YD F LP N+C YAV+DF++
Sbjct: 11 FLELKSKRNYRFIIFRI-DGQQVVVEKLGNPDETYDDFTASLPANECRYAVFDFDFITDE 69
Query: 64 NEGKRSKIVFFTWSPDTAPVRSKMVYASSKDALRRALNGVSSDIQGTDFSEVAYESV 120
N ++SKI F WSPD++ VR KMVYASSKD +R L+G+ ++Q TD SE++++ +
Sbjct: 70 N-CQKSKIFFIAWSPDSSRVRMKMVYASSKDRFKRELDGIQVELQATDPSEMSFDII 125
>At4g34970 [Z] KOG1735 Actin depolymerizing factor
Length = 130
Score = 99.8 bits (247), Expect = 9e-22
Identities = 47/122 (38%), Positives = 80/122 (65%), Gaps = 2/122 (1%)
Query: 3 AFNDLKLGKKYKFILYALNDSKTEIIV-KETSAEQDYDKFLEQLPENDCLYAVYDFEYEL 61
+F ++K K +++++Y L + ++ V K +A + YD LPE+DC YAV+DF+Y
Sbjct: 8 SFMEMKWKKVHRYVVYKLEEKSRKVTVDKVGAAGESYDDLAASLPEDDCRYAVFDFDYVT 67
Query: 62 GNNEGKRSKIVFFTWSPDTAPVRSKMVYASSKDALRRALNGVSSDIQGTDFSEVAYESVL 121
+N + SKI F TWSP+ + +R KM+YA+SK LRR L+GV ++Q TD +E+ ++ +
Sbjct: 68 VDN-CRMSKIFFITWSPEASRIREKMMYATSKSGLRRVLDGVHYELQATDPTEMGFDKIQ 126
Query: 122 EK 123
++
Sbjct: 127 DR 128
>At3g46010 [Z] KOG1735 Actin depolymerizing factor
Length = 139
Score = 97.1 bits (240), Expect = 6e-21
Identities = 45/113 (39%), Positives = 75/113 (65%), Gaps = 2/113 (1%)
Query: 4 FNDLKLGKKYKFILYALNDSKTEIIVKETSAE-QDYDKFLEQLPENDCLYAVYDFEYELG 62
F +LK + ++FI+Y + + + +++V++ Q Y++F LP ++C YA+YDF++
Sbjct: 18 FLELKAKRTHRFIVYKIEEKQKQVVVEKVGQPIQTYEEFAACLPADECRYAIYDFDFVTA 77
Query: 63 NNEGKRSKIVFFTWSPDTAPVRSKMVYASSKDALRRALNGVSSDIQGTDFSEV 115
N ++SKI F W PD A VRSKM+YASSKD +R L+G+ ++Q TD +E+
Sbjct: 78 EN-CQKSKIFFIAWCPDIAKVRSKMIYASSKDRFKRELDGIQVELQATDPTEM 129
>At5g59890 [Z] KOG1735 Actin depolymerizing factor
Length = 132
Score = 96.7 bits (239), Expect = 7e-21
Identities = 46/123 (37%), Positives = 78/123 (63%), Gaps = 2/123 (1%)
Query: 4 FNDLKLGKKYKFILYALNDSKTEIIVKETSAE-QDYDKFLEQLPENDCLYAVYDFEYELG 62
F +LK + ++FI+Y + + + ++IV++ Y+ F LP ++C YA+YDF++
Sbjct: 11 FLELKAKRTHRFIVYKIEEKQKQVIVEKVGEPILTYEDFAASLPADECRYAIYDFDFVTA 70
Query: 63 NNEGKRSKIVFFTWSPDTAPVRSKMVYASSKDALRRALNGVSSDIQGTDFSEVAYESVLE 122
N ++SKI F W PD A VRSKM+YASSKD +R L+G+ ++Q TD +E+ + +
Sbjct: 71 EN-CQKSKIFFIAWCPDVAKVRSKMIYASSKDRFKRELDGIQVELQATDPTEMDLDVLKS 129
Query: 123 KVS 125
+V+
Sbjct: 130 RVN 132
>Hs14719392 [Z] KOG1735 Actin depolymerizing factor
Length = 166
Score = 94.4 bits (233), Expect = 4e-20
Identities = 50/140 (35%), Positives = 78/140 (55%), Gaps = 21/140 (15%)
Query: 1 MNAFNDLK---------LGKKYKFILYALNDSKTEIIVKET----------SAEQDYDKF 41
+ FND+K + K+ K +L+ L+D K +IIV+E + E Y F
Sbjct: 12 IKVFNDMKVRKSSTQEEIKKRKKAVLFCLSDDKRQIIVEEAKQILVGDIGDTVEDPYTSF 71
Query: 42 LEQLPENDCLYAVYDFEYELGNNEGKRSKIVFFTWSPDTAPVRSKMVYASSKDALRRALN 101
++ LP NDC YA+YD YE E K+ +VF W+P++AP++SKM+YASSKDA+++
Sbjct: 72 VKLLPLNDCRYALYDATYE--TKESKKEDLVFIFWAPESAPLKSKMIYASSKDAIKKKFT 129
Query: 102 GVSSDIQGTDFSEVAYESVL 121
G+ + Q ++ S L
Sbjct: 130 GIKHEWQVNGLDDIKDRSTL 149
>Hs5031635 [Z] KOG1735 Actin depolymerizing factor
Length = 166
Score = 94.0 bits (232), Expect = 5e-20
Identities = 51/148 (34%), Positives = 84/148 (56%), Gaps = 22/148 (14%)
Query: 1 MNAFNDLKLGK---------KYKFILYALNDSKTEIIVKE----------TSAEQDYDKF 41
+ FND+K+ K + K +L+ L++ K II++E + + Y F
Sbjct: 12 IKVFNDMKVRKSSTPEEVKKRKKAVLFCLSEDKKNIILEEGKEILVGDVGQTVDDPYATF 71
Query: 42 LEQLPENDCLYAVYDFEYELGNNEGKRSKIVFFTWSPDTAPVRSKMVYASSKDALRRALN 101
++ LP+ DC YA+YD YE E K+ +VF W+P++AP++SKM+YASSKDA+++ L
Sbjct: 72 VKMLPDKDCRYALYDATYE--TKESKKEDLVFIFWAPESAPLKSKMIYASSKDAIKKKLT 129
Query: 102 GVSSDIQGTDFSEVAYESVL-EKVSRAA 128
G+ ++Q + EV L EK+ +A
Sbjct: 130 GIKHELQANCYEEVKDRCTLAEKLGGSA 157
>At5g59880 [Z] KOG1735 Actin depolymerizing factor
Length = 132
Score = 93.6 bits (231), Expect = 6e-20
Identities = 46/114 (40%), Positives = 77/114 (67%), Gaps = 4/114 (3%)
Query: 4 FNDLKLGKKYKFILYALNDSKTEIIVKETSAE-QDYDKFLEQLPENDCLYAVYDFEYELG 62
F +LK + ++FI+Y + + + ++IV++ Q ++ LP ++C YA++DF++
Sbjct: 11 FMELKTKRTHRFIIYKIEELQKQVIVEKIGEPGQTHEDLAASLPADECRYAIFDFDFV-- 68
Query: 63 NNEG-KRSKIVFFTWSPDTAPVRSKMVYASSKDALRRALNGVSSDIQGTDFSEV 115
++EG RS+I F WSPDTA VRSKM+YASSKD +R L+G+ ++Q TD +E+
Sbjct: 69 SSEGVPRSRIFFVAWSPDTARVRSKMIYASSKDRFKRELDGIQVELQATDPTEM 122
>At2g16700 [Z] KOG1735 Actin depolymerizing factor
Length = 132
Score = 92.0 bits (227), Expect = 2e-19
Identities = 42/123 (34%), Positives = 80/123 (64%), Gaps = 2/123 (1%)
Query: 2 NAFNDLKLGKKYKFILYALNDSKTEIIV-KETSAEQDYDKFLEQLPENDCLYAVYDFEYE 60
++F D+K K +++I++ + + ++ V K A + Y + LP +DC YAV+DF++
Sbjct: 9 SSFMDMKWKKVHRYIVFKIEEKSRKVTVDKVGGAGESYHDLEDSLPVDDCRYAVFDFDFV 68
Query: 61 LGNNEGKRSKIVFFTWSPDTAPVRSKMVYASSKDALRRALNGVSSDIQGTDFSEVAYESV 120
+N ++SKI F WSP+ + +R+K++YA+SKD LRR L G+ ++Q TD +E+ ++ +
Sbjct: 69 TVDN-CRKSKIFFIAWSPEASKIRAKILYATSKDGLRRVLEGIHYELQATDPTEMGFDII 127
Query: 121 LEK 123
++
Sbjct: 128 QDR 130
>7291724 [Z] KOG1735 Actin depolymerizing factor
Length = 148
Score = 92.0 bits (227), Expect = 2e-19
Identities = 47/128 (36%), Positives = 78/128 (60%), Gaps = 7/128 (5%)
Query: 4 FNDLKLGKKYKFILYALNDSKTEIIVKETSAEQDYDKFLEQLPE---NDCLYAVYDFEYE 60
+ ++K KK++++++ + D K + +YD+FLE + + +C Y ++DFEY
Sbjct: 15 YEEIKKDKKHRYVIFYIRDEKQIDVETVADRNAEYDQFLEDIQKCGPGECRYGLFDFEYM 74
Query: 61 ---LGNNEG-KRSKIVFFTWSPDTAPVRSKMVYASSKDALRRALNGVSSDIQGTDFSEVA 116
G +E K+ K+ +W PDTA V+ KM+Y+SS DAL+++L GV IQ TD SE +
Sbjct: 75 HQCQGTSESSKKQKLFLMSWCPDTAKVKKKMLYSSSFDALKKSLVGVQKYIQATDLSEAS 134
Query: 117 YESVLEKV 124
E+V EK+
Sbjct: 135 REAVEEKL 142
>Hs22042272 [Z] KOG1735 Actin depolymerizing factor
Length = 154
Score = 85.5 bits (210), Expect = 2e-17
Identities = 52/148 (35%), Positives = 79/148 (53%), Gaps = 23/148 (15%)
Query: 1 MNAFNDLKLGKKY---------KFILYALNDSKTEIIVKET----------SAEQDYDKF 41
MN FND+KL K K +L+ L++ K II++ET + + Y F
Sbjct: 1 MNMFNDMKLHKSSMPEEVKKLKKVVLFCLSEDKKNIILEETKKILVGDVSQTIDDPYTTF 60
Query: 42 LEQLPENDCLYAVYDFEYELGNNEGKRSKIVFFTWSPDTAPVRSKMVYASSKDALRRALN 101
+ LP+ DC Y + D YE E K +VF W P++AP++SKM+YASSKDA+++ L
Sbjct: 61 VRMLPDKDCHYTLCDTTYE--TKESKEEDLVFIFWVPESAPLKSKMIYASSKDAVKK-LT 117
Query: 102 GVSSDIQGTDFSEVAYESVL-EKVSRAA 128
G+ ++ + EV L EK+ +A
Sbjct: 118 GIKHELHTNCYKEVKDRCTLAEKLGGSA 145
>At3g45990 [Z] KOG1735 Actin depolymerizing factor
Length = 133
Score = 85.1 bits (209), Expect = 2e-17
Identities = 40/128 (31%), Positives = 72/128 (56%), Gaps = 11/128 (8%)
Query: 4 FNDLKLGKKYKFILYALNDSKTEIIVKET------SAEQDYDKFLEQLPENDCLYAVYDF 57
F +LK + ++ I+Y + D+ I+ K EQ Y++F LP ++C YA+ D
Sbjct: 11 FLELKERRTFRSIVYKIEDNMQVIVEKHHYKKMHGEREQSYEEFANSLPADECRYAILDI 70
Query: 58 EYELGNNEGKRSKIVFFTWSPDTAPVRSKMVYASSKDALRRALNGVSSDIQGTDFSEVAY 117
E+ G KI F WSP TA +R KM+Y+S+KD +R L+G+ + TD ++++
Sbjct: 71 EFVPGER-----KICFIAWSPSTAKMRKKMIYSSTKDRFKRELDGIQVEFHATDLTDISL 125
Query: 118 ESVLEKVS 125
+++ +++
Sbjct: 126 DAIRRRIN 133
>Hs5802966 [Z] KOG1735 Actin depolymerizing factor
Length = 165
Score = 82.0 bits (201), Expect = 2e-16
Identities = 40/127 (31%), Positives = 72/127 (56%), Gaps = 12/127 (9%)
Query: 8 KLGKKYKFILYALNDSKTEIIVKE----------TSAEQDYDKFLEQLPENDCLYAVYDF 57
++ K+ K +++ L+ K IIV+E + + F+ LPE DC YA+YD
Sbjct: 28 EIKKRKKAVIFCLSADKKCIIVEEGKEILVGDVGVTITDPFKHFVGMLPEKDCRYALYDA 87
Query: 58 EYELGNNEGKRSKIVFFTWSPDTAPVRSKMVYASSKDALRRALNGVSSDIQGTDFSEVAY 117
+E E ++ +++FF W+P+ AP++SKM+YASSKDA+++ G+ + Q ++
Sbjct: 88 SFE--TKESRKEELMFFLWAPELAPLKSKMIYASSKDAIKKKFQGIKHECQANGPEDLNR 145
Query: 118 ESVLEKV 124
+ EK+
Sbjct: 146 ACIAEKL 152
>CE20547 [Z] KOG1735 Actin depolymerizing factor
Length = 165
Score = 71.2 bits (173), Expect = 3e-13
Identities = 47/155 (30%), Positives = 80/155 (51%), Gaps = 29/155 (18%)
Query: 3 AFNDLKLGKK-YKFILYALNDSKTEIIVKETSAEQD----------------YDKFLEQL 45
+F L G+K Y++I++ ++++K ++ E + QD +DKF+E +
Sbjct: 14 SFQKLSEGRKEYRYIIFKIDENK---VIVEAAVTQDQLGITGDDYDDSSKAAFDKFVEDV 70
Query: 46 PEN-----DCLYAVYDFEY---ELGNNEGKRSKIVFFTWSPDTAPVRSKMVYASSKDALR 97
DC YAV+DF++ +G K KI+F PD A ++ KMVYASS A++
Sbjct: 71 KSRTDNLTDCRYAVFDFKFTCSRVGAGTSKMDKIIFLQICPDGASIKKKMVYASSAAAIK 130
Query: 98 RAL-NGVSSDIQGTDFSEVAYESVLEKVSRAAGSH 131
+L G Q +D SE++++ +L K+ G H
Sbjct: 131 TSLGTGKILQFQVSDESEMSHKELLNKLGEKYGDH 165
>Hs22057868 [Z] KOG1735 Actin depolymerizing factor
Length = 135
Score = 62.8 bits (151), Expect = 1e-10
Identities = 31/85 (36%), Positives = 50/85 (58%), Gaps = 6/85 (7%)
Query: 26 EIIVKETSA--EQDYDKFLEQLPENDCLYAVYDFEYELGNNEGKRSKIVFFTWSPDTAPV 83
EI+V + + + F+ LPE DC YA+YD +E E +R + F W+ + AP+
Sbjct: 36 EILVGDVGVTISEPFKHFVGMLPEKDCCYALYDASFE--TKESRRIDV--FLWASELAPL 91
Query: 84 RSKMVYASSKDALRRALNGVSSDIQ 108
+SKM+Y SSKDA+++ G+ + Q
Sbjct: 92 KSKMIYTSSKDAIKKKFQGIKHEWQ 116
>7293502 [Z] KOG1735 Actin depolymerizing factor
Length = 148
Score = 62.0 bits (149), Expect = 2e-10
Identities = 37/131 (28%), Positives = 66/131 (50%), Gaps = 9/131 (6%)
Query: 2 NAFNDLKLGKKYKFILYALNDSKTEIIVKETSAEQDYDKFLEQLPE---NDCLYAVYDFE 58
+ F ++ K++++ ++ + D + + E +YD FL L N C +AVYD+E
Sbjct: 13 HVFEQIRKLKQHRYAVFVIQDEREIKVEVLGVREANYDDFLADLQRAGSNQCRFAVYDYE 72
Query: 59 YELGNNEGKRS-----KIVFFTWSPDTAPVRSKMVYASSKDALRRALNGVSSDIQGTDFS 113
Y+ +G S K++ W P A ++ KM+Y+S+ L+R GV IQ T+
Sbjct: 73 YQ-HQCQGTLSTCLKEKLILMLWCPTLARIKDKMLYSSTFAVLKREFPGVQKCIQATEPE 131
Query: 114 EVAYESVLEKV 124
E +V E++
Sbjct: 132 EACRNAVEEQL 142
>Hs17439599 [Z] KOG1735 Actin depolymerizing factor
Length = 181
Score = 61.6 bits (148), Expect = 3e-10
Identities = 34/101 (33%), Positives = 56/101 (54%), Gaps = 11/101 (10%)
Query: 8 KLGKKYKFILYALNDSKTEIIV---KETSAEQ-------DYDKFLEQLPENDCLYAVYDF 57
++ K+ K +++ L+ K IIV KE SA + F+ LPE DC YA+YD
Sbjct: 50 EIKKRKKTVIFCLSADKKCIIVEEGKEISAGDIGVTITGPFKHFVGMLPEKDCCYALYDA 109
Query: 58 EYELGNNEGKRSKIVFFTWSPDTAPVRSKMVYASSKDALRR 98
+E G+ + F W+P+ P++SKM++ S KDA+++
Sbjct: 110 SFET-KKSGRVLFVCLFLWAPELPPLKSKMIFTSCKDAIKK 149
>CE20548 [Z] KOG1735 Actin depolymerizing factor
Length = 293
Score = 59.7 bits (143), Expect = 1e-09
Identities = 38/123 (30%), Positives = 64/123 (51%), Gaps = 28/123 (22%)
Query: 3 AFNDLKLGKK-YKFILYALNDSKTEIIVKETSAEQD----------------YDKFLEQL 45
+F L G+K Y++I++ ++++K ++ E + QD +DKF+E +
Sbjct: 14 SFQKLSEGRKEYRYIIFKIDENK---VIVEAAVTQDQLGITGDDYDDSSKAAFDKFVEDV 70
Query: 46 PEN-----DCLYAVYDFEY---ELGNNEGKRSKIVFFTWSPDTAPVRSKMVYASSKDALR 97
DC YAV+DF++ +G K KI+F PD A ++ KMVYASS A++
Sbjct: 71 KSRTDNLTDCRYAVFDFKFTCSRVGAGTSKMDKIIFLQICPDGASIKKKMVYASSAAAIK 130
Query: 98 RAL 100
+L
Sbjct: 131 TSL 133
Score = 57.4 bits (137), Expect = 5e-09
Identities = 39/131 (29%), Positives = 75/131 (56%), Gaps = 13/131 (9%)
Query: 2 NAFNDLKLGKKYKFILYALNDSKTEIIVKETSAEQ-DYDKFLEQLPE-----NDCLYAVY 55
NA++ L ++ +I++ ++ + T I+V++ + Y +F+E++ + +C YA
Sbjct: 154 NAYDLLHNKHQHSYIIFKIDKNDTAIVVEKVGEKNAPYAEFVEEMKKLVEDGKECRYAAV 213
Query: 56 DFEYELGNN--EGKRS--KIVFFTWSPDTAPVRSKMVYASSKDALRRALNGVSS--DIQG 109
D E + EG + K++F + PD APVR +M+YASS AL+ +L G+ S +Q
Sbjct: 214 DVEVTVQRQGAEGTSTLNKVIFVQYCPDNAPVRRRMLYASSVRALKASL-GLESLFQVQA 272
Query: 110 TDFSEVAYESV 120
++ S++ +SV
Sbjct: 273 SEMSDLDEKSV 283
>CE20549 [Z] KOG1735 Actin depolymerizing factor
Length = 152
Score = 57.4 bits (137), Expect = 5e-09
Identities = 39/131 (29%), Positives = 75/131 (56%), Gaps = 13/131 (9%)
Query: 2 NAFNDLKLGKKYKFILYALNDSKTEIIVKETSAEQ-DYDKFLEQLPE-----NDCLYAVY 55
NA++ L ++ +I++ ++ + T I+V++ + Y +F+E++ + +C YA
Sbjct: 13 NAYDLLHNKHQHSYIIFKIDKNDTAIVVEKVGEKNAPYAEFVEEMKKLVEDGKECRYAAV 72
Query: 56 DFEYELGNN--EGKRS--KIVFFTWSPDTAPVRSKMVYASSKDALRRALNGVSS--DIQG 109
D E + EG + K++F + PD APVR +M+YASS AL+ +L G+ S +Q
Sbjct: 73 DVEVTVQRQGAEGTSTLNKVIFVQYCPDNAPVRRRMLYASSVRALKASL-GLESLFQVQA 131
Query: 110 TDFSEVAYESV 120
++ S++ +SV
Sbjct: 132 SEMSDLDEKSV 142
>Hs17435363 [Z] KOG1735 Actin depolymerizing factor
Length = 153
Score = 49.3 bits (116), Expect = 1e-06
Identities = 35/134 (26%), Positives = 58/134 (43%), Gaps = 34/134 (25%)
Query: 1 MNAFNDLKLGKKY---------KFILYALNDSKTEIIVKE----------TSAEQDYDKF 41
+ F D+K+ K K + + L++ K II++E + Y F
Sbjct: 12 IKVFKDMKMHKSSMPEEVKKCKKVVFFCLSEDKKNIILEEGKEILVGDVGQTVNNLYATF 71
Query: 42 LEQLPENDCLYAVYDFEYELGNNEGKRSKIVFFTWSPDTAPVRSKMVYASSKDALRRALN 101
++ LP D Y +YD YE E K + SK++YASSKDA+++ L
Sbjct: 72 VKMLPYKDYRYTLYDTTYE--TKESKEEDL-------------SKIIYASSKDAIKKKLT 116
Query: 102 GVSSDIQGTDFSEV 115
G+ +Q + +V
Sbjct: 117 GIKHALQANCYEDV 130
>Hs17433952 [Z] KOG1735 Actin depolymerizing factor
Length = 108
Score = 47.4 bits (111), Expect = 5e-06
Identities = 25/66 (37%), Positives = 35/66 (52%), Gaps = 7/66 (10%)
Query: 38 YDKFLEQLPENDCLYAVYDFEYELGNNEGKR-------SKIVFFTWSPDTAPVRSKMVYA 90
+ F+ LPENDC YA+YD +E + + KI F P++SK+ YA
Sbjct: 43 FKHFVGMLPENDCCYALYDAHFETKESRKEELMGFCGVFKIFFVCVGTQLEPMKSKLSYA 102
Query: 91 SSKDAL 96
SSKDA+
Sbjct: 103 SSKDAI 108
>Hs6005846 [W] KOG1747 Protein tyrosine kinase 9/actin monomer-binding protein
Length = 349
Score = 46.6 bits (109), Expect = 9e-06
Identities = 27/96 (28%), Positives = 51/96 (53%), Gaps = 5/96 (5%)
Query: 35 EQDYDKFLEQLPENDCLYAVYDFEYELGNNEGKRSKIVFFTWSPDTAPVRSKMVYASSKD 94
+QDYD+ + LP D Y Y L + + + +F WSPD +PVR KM+YA+++
Sbjct: 50 DQDYDRAV--LPLLDAQQPCY-LLYRLDSQNAQGFEWLFLAWSPDNSPVRLKMLYAATRA 106
Query: 95 ALRRALNG--VSSDIQGTDFSEVAYESVLEKVSRAA 128
+++ G + ++ GT ++++ + +S A
Sbjct: 107 TVKKEFGGGHIKDELFGTVKDDLSFAGYQKHLSSCA 142
>7299845 [W] KOG1747 Protein tyrosine kinase 9/actin monomer-binding protein
Length = 343
Score = 45.8 bits (107), Expect = 1e-05
Identities = 30/89 (33%), Positives = 45/89 (49%), Gaps = 11/89 (12%)
Query: 35 EQDYDKFLEQLPENDC-LYAVY--DFEYELGNNEGKRSKIVFFTWSPDTAPVRSKMVYAS 91
E+DYDK + L E D Y +Y D + LG + + +W+PDTA +R KMVYAS
Sbjct: 50 ERDYDKLIGPLLEKDVPCYILYRLDAKIPLGYSW------LLISWTPDTASIRQKMVYAS 103
Query: 92 SKDALRRALNG--VSSDIQGTDFSEVAYE 118
+K L+ ++ ++ T E E
Sbjct: 104 TKATLKTEFGSAYITEELHATTLDECTLE 132
>Hs22044643 [Z] KOG1735 Actin depolymerizing factor
Length = 180
Score = 45.1 bits (105), Expect = 2e-05
Identities = 18/45 (40%), Positives = 32/45 (71%), Gaps = 4/45 (8%)
Query: 75 TW----SPDTAPVRSKMVYASSKDALRRALNGVSSDIQGTDFSEV 115
TW P++AP++SKM+YA+SKD +++ L G+ ++Q ++EV
Sbjct: 113 TWCSASGPESAPLKSKMIYANSKDTIKKKLTGIKHELQANCYAEV 157
>Hs4506275 [W] KOG1747 Protein tyrosine kinase 9/actin monomer-binding protein
Length = 350
Score = 42.0 bits (97), Expect = 2e-04
Identities = 25/87 (28%), Positives = 46/87 (52%), Gaps = 7/87 (8%)
Query: 33 SAEQDYDKF-LEQLPENDCLYAVYDFEYELGNNEGKRSKIVFFTWSPDTAPVRSKMVYAS 91
S ++DYD F L L + Y ++ L + + + +F WSPD + VR KM+YA+
Sbjct: 48 SWDKDYDSFVLPLLEDKQPCYILF----RLDSQNAQGYEWIFIAWSPDHSHVRQKMLYAA 103
Query: 92 SKDALRRALNG--VSSDIQGTDFSEVA 116
++ L++ G + ++ GT +V+
Sbjct: 104 TRATLKKEFGGGHIKDEVFGTVKEDVS 130
>SPCC126.06 [W] KOG1747 Protein tyrosine kinase 9/actin monomer-binding protein
Length = 328
Score = 39.7 bits (91), Expect = 0.001
Identities = 29/107 (27%), Positives = 53/107 (49%), Gaps = 9/107 (8%)
Query: 22 DSKTEIIVKETSAEQDYDKFLEQLPENDCLYAVYDFEYELGNNEGKRSKIVFFTWSPDTA 81
D KT ++ K S E D+ K E CL + + L ++ K++ + ++ P+ A
Sbjct: 39 DVKT-MVEKSESIESDFKKVRE------CLLGSEEPAFVLVYDDSKKNLLQLISYVPENA 91
Query: 82 PVRSKMVYASSKDALRRALNGVSSDIQ--GTDFSEVAYESVLEKVSR 126
VR KM+YASS+ A R + D + E+ Y+ +++ +S+
Sbjct: 92 NVRRKMLYASSRAAFVRCVTLAKLDESYFASTPEELDYQQIMKSLSK 138
Score = 31.2 bits (69), Expect = 0.37
Identities = 27/127 (21%), Positives = 54/127 (42%), Gaps = 15/127 (11%)
Query: 1 MNAFNDLKLGKKYKFILYALNDSKTEIIV-KETSAEQDYDKFLEQLPENDCLYAVYDFEY 59
+ A +DLK + ++ +++ + K+ D F N Y++
Sbjct: 183 LKALSDLKSSTENNLVILSIDKEVISLSQEKQNIPPSDVKSFFSSTEPNFAFYSL----- 237
Query: 60 ELGNNEGKRSKIVFFTWSPDTAPVRSKMVYASSK----DALRRALN-GVSSDIQGTDFSE 114
+ SKI+F P A V+ +MVY+SSK D+++ L + I+ D ++
Sbjct: 238 ----PKDGSSKILFIYICPMQATVKHRMVYSSSKLGLLDSIKAELGIVIDGKIESNDAAD 293
Query: 115 VAYESVL 121
+ + +L
Sbjct: 294 ITEKEIL 300
>YCR088w [Z] KOG3655 Drebrins and related actin binding proteins
Length = 592
Score = 35.8 bits (81), Expect = 0.015
Identities = 18/62 (29%), Positives = 34/62 (54%), Gaps = 1/62 (1%)
Query: 70 KIVFFTWSPDTAPVRSKMVYASSKDALRRAL-NGVSSDIQGTDFSEVAYESVLEKVSRAA 128
KI+ W PD+AP++++ +A++ A+ L G + D ++ +L K+S AA
Sbjct: 80 KIIIIGWCPDSAPLKTRASFAANFAAVANNLFKGYHVQVTARDEDDLDENELLMKISNAA 139
Query: 129 GS 130
G+
Sbjct: 140 GA 141
>YGR080w [W] KOG1747 Protein tyrosine kinase 9/actin monomer-binding protein
Length = 332
Score = 35.0 bits (79), Expect = 0.026
Identities = 16/35 (45%), Positives = 24/35 (67%)
Query: 70 KIVFFTWSPDTAPVRSKMVYASSKDALRRALNGVS 104
K F ++ PD +PVRS+M+YAS+K+ L R + S
Sbjct: 74 KYFFVSFIPDGSPVRSRMLYASTKNTLARQVGSNS 108
>Hs4758442 [W] KOG1736 Glia maturation factor beta
Length = 142
Score = 33.5 bits (75), Expect = 0.075
Identities = 21/82 (25%), Positives = 42/82 (50%), Gaps = 3/82 (3%)
Query: 16 ILYALNDSKTEIIVKETSAEQDYDKFLEQLPENDCLYAVYDFEYELGNNEGKRS-KIVFF 74
I+ ++ K +++ E D+ ++LPE + VY ++Y+ +++G+ S + F
Sbjct: 32 IIMKIDKDKRLVVLDEELEGISPDELKDELPERQPRFIVYSYKYQ--HDDGRVSYPLCFI 89
Query: 75 TWSPDTAPVRSKMVYASSKDAL 96
SP +M+YA SK+ L
Sbjct: 90 FSSPVGCKPEQQMMYAGSKNKL 111
>Hs18571222 [Z] KOG1735 Actin depolymerizing factor
Length = 103
Score = 33.1 bits (74), Expect = 0.098
Identities = 20/77 (25%), Positives = 36/77 (45%), Gaps = 12/77 (15%)
Query: 8 KLGKKYKFILYALNDSKTEIIVKE----------TSAEQDYDKFLEQLPENDCLYAVYDF 57
++ K+ K +++ L + IIV+E + + F+ LPE DC A+YD
Sbjct: 28 EIKKRKKAVIFCLGADEKCIIVEEGKEILVGDVGVTITGPFKHFVGMLPEKDCRCALYDA 87
Query: 58 EYELGNNEGKRSKIVFF 74
+E E +++FF
Sbjct: 88 SFE--TKESSTEELIFF 102
>Hs20561421 [Z] KOG3655 Drebrins and related actin binding proteins
Length = 142
Score = 32.3 bits (72), Expect = 0.17
Identities = 22/105 (20%), Positives = 46/105 (42%), Gaps = 4/105 (3%)
Query: 27 IIVKETSAEQDYDKFLEQLPENDCLYAVYDFEYELGNNEGKRSKIVFFTWSPDTAPVRSK 86
I+ E AE Y F++Q ++ L+A F G+ KRSK TW + +
Sbjct: 36 IVPGEQGAE--YQHFIQQCTDDVRLFAFVRFT--TGDAMSKRSKFALITWIGENVSGLQR 91
Query: 87 MVYASSKDALRRALNGVSSDIQGTDFSEVAYESVLEKVSRAAGSH 131
+ K ++ + + + +D E+ + + ++ +A G++
Sbjct: 92 AKTGTDKTLVKEVVQNFAKEFVISDRKELEEDFIKSELKKAGGAN 136
>Hs22057765 [Z] KOG1735 Actin depolymerizing factor
Length = 577
Score = 31.6 bits (70), Expect = 0.29
Identities = 13/36 (36%), Positives = 20/36 (55%), Gaps = 2/36 (5%)
Query: 46 PENDCLYAVYDFEYELGNNEGKRSKIVFFTWSPDTA 81
P+ DC Y +YD E E + +VF W+P++A
Sbjct: 370 PDKDCHYVLYDAALE--TKESTKRDLVFIFWAPESA 403
>SPAC17H9.11 [W] KOG1736 Glia maturation factor beta
Length = 141
Score = 29.6 bits (65), Expect = 1.1
Identities = 28/117 (23%), Positives = 49/117 (40%), Gaps = 4/117 (3%)
Query: 7 LKLGKKYKFILYALNDSKTEIIVKETSAEQDYDKFLEQLPENDCLYAVYDFEYELGNNEG 66
LK Y FIL +K + E Q ++ ++L E + + + Y +G
Sbjct: 25 LKKSVMYAFILKVDKATKEIVPDGEIMDLQSIEEVADELSETNPRFILVS--YPTKTTDG 82
Query: 67 KRSKIVFFT-WSPDTAPVRSKMVYASSKDALRRALNGVSSDIQGTDFSEVAYESVLE 122
+ S +F W P P M+YAS+K + ++ V + D ++ E+V E
Sbjct: 83 RLSTPLFMIYWRPSATPNDLSMIYASAK-VWFQDVSQVHKVFEARDSEDITSEAVDE 138
>Hs4758440 [W] KOG1736 Glia maturation factor beta
Length = 142
Score = 29.6 bits (65), Expect = 1.1
Identities = 19/82 (23%), Positives = 41/82 (49%), Gaps = 3/82 (3%)
Query: 16 ILYALNDSKTEIIVKETSAEQDYDKFLEQLPENDCLYAVYDFEYELGNNEGKRS-KIVFF 74
I+ ++ + ++++E ++ +LPE + VY ++Y +++G+ S + F
Sbjct: 32 IIMKVDKDRQMVVLEEEFQNISPEELKMELPERQPRFVVYSYKYV--HDDGRVSYPLCFI 89
Query: 75 TWSPDTAPVRSKMVYASSKDAL 96
SP +M+YA SK+ L
Sbjct: 90 FSSPVGCKPEQQMMYAGSKNRL 111
>7293631 [OR] KOG0010 Ubiquitin-like protein
Length = 547
Score = 29.6 bits (65), Expect = 1.1
Identities = 20/63 (31%), Positives = 32/63 (50%), Gaps = 1/63 (1%)
Query: 63 NNEGKRSKIVFFTWSPDTAPVRSKMVYASSKDALRRALNGVSSDIQGTDFSEVAYESVLE 122
NN S + T +P+ AP + D + R LNG+S++ T EV Y+S LE
Sbjct: 449 NNVSPSSGLNAGTGTPNLAPGGGPNAQLFN-DFMMRMLNGMSNNADNTQPPEVRYQSQLE 507
Query: 123 KVS 125
+++
Sbjct: 508 QLN 510
>SPBC646.03 [J] KOG1211 Amidases
Length = 471
Score = 28.9 bits (63), Expect = 1.9
Identities = 15/42 (35%), Positives = 22/42 (51%)
Query: 2 NAFNDLKLGKKYKFILYALNDSKTEIIVKETSAEQDYDKFLE 43
N +N+L K+ LND+K + + SAE YD F+E
Sbjct: 3 NKYNNLLKEVAAKYASIILNDAKIKSLTSINSAEYLYDSFVE 44
>SPAC4F10.21 [R] KOG1128 Uncharacterized conserved protein contains TPR repeats
Length = 276
Score = 28.5 bits (62), Expect = 2.4
Identities = 23/72 (31%), Positives = 37/72 (50%), Gaps = 8/72 (11%)
Query: 54 VYDFEYELGNNEGKRSKIVFFTWSPDTAPVRSKMVYASSKDALRRALNGVSSDIQGTDFS 113
V DF +EL G+R+K F DT+ + +V A S+D + S+ Q F
Sbjct: 209 VMDFHFELTGALGRRTKFQTF----DTSQL---VVLAKSRDRCKDTEQNKSTSTQPITF- 260
Query: 114 EVAYESVLEKVS 125
E+ +++LEK+S
Sbjct: 261 ELNDDTLLEKIS 272
>HsM7661718 [Z] KOG3655 Drebrins and related actin binding proteins
Length = 430
Score = 28.5 bits (62), Expect = 2.4
Identities = 28/115 (24%), Positives = 47/115 (40%), Gaps = 5/115 (4%)
Query: 17 LYALNDSKTEIIVKETSAEQDYDKFLEQLPENDCLYAVYDFEYELGNNEGKRSKIVFFTW 76
L+ + +I V T E ++ +E+L +YA F N G K V W
Sbjct: 30 LFTYEGNSNDIRVAGTG-EGGLEEMVEELNSGKVMYA---FCRVKDPNSGL-PKFVLINW 84
Query: 77 SPDTAPVRSKMVYASSKDALRRALNGVSSDIQGTDFSEVAYESVLEKVSRAAGSH 131
+ + K AS + L G I +V E ++EKV++A+G++
Sbjct: 85 TGEGVNDVRKGACASHVSTMASFLKGAHVTINARAEEDVEPECIMEKVAKASGAN 139
>Hs21361670 [Z] KOG3655 Drebrins and related actin binding proteins
Length = 431
Score = 28.5 bits (62), Expect = 2.4
Identities = 28/115 (24%), Positives = 47/115 (40%), Gaps = 5/115 (4%)
Query: 17 LYALNDSKTEIIVKETSAEQDYDKFLEQLPENDCLYAVYDFEYELGNNEGKRSKIVFFTW 76
L+ + +I V T E ++ +E+L +YA F N G K V W
Sbjct: 30 LFTYEGNSNDIRVAGTG-EGGLEEMVEELNSGKVMYA---FCRVKDPNSGL-PKFVLINW 84
Query: 77 SPDTAPVRSKMVYASSKDALRRALNGVSSDIQGTDFSEVAYESVLEKVSRAAGSH 131
+ + K AS + L G I +V E ++EKV++A+G++
Sbjct: 85 TGEGVNDVRKGACASHVSTMASFLKGAHVTINARAEEDVEPECIMEKVAKASGAN 139
>7293118 [R] KOG1721 FOG: Zn-finger
Length = 762
Score = 28.5 bits (62), Expect = 2.4
Identities = 15/60 (25%), Positives = 26/60 (43%), Gaps = 9/60 (15%)
Query: 17 LYALNDSKTEIIVKETSAEQDYD---------KFLEQLPENDCLYAVYDFEYELGNNEGK 67
+Y+ ND ++ +VKETS + + K L + C Y +D +Y G+
Sbjct: 347 VYSYNDKMSDAVVKETSYRRRFSAIWNDTSTAKLLSMVKRYQCFYNRFDPDYRSKERRGE 406
>SPCC16C4.07 [R] KOG0118 FOG: RRM domain
Length = 561
Score = 28.1 bits (61), Expect = 3.2
Identities = 17/53 (32%), Positives = 27/53 (50%), Gaps = 3/53 (5%)
Query: 65 EGKRSKIVFFTWSPDTAPVRSKMVYASSKDALRRALNGVSSDIQGTDFSEVAY 117
EG S + F S + +P R + ++D RR+ N VS+ + + SE AY
Sbjct: 200 EGSESSVSFNRLSRNHSPTRPLL---GNRDLFRRSSNHVSASMPTANHSESAY 249
>Hs20127501 [A] KOG2560 RNA splicing factor - Slu7p
Length = 586
Score = 28.1 bits (61), Expect = 3.2
Identities = 32/124 (25%), Positives = 46/124 (36%), Gaps = 25/124 (20%)
Query: 22 DSKTEIIVKETSAEQDYDKFLEQLPENDCLY-----AVYDFEYELGNNEGKRSKIV---- 72
DSK I V+ +D K+L L N Y A+ + Y N GK V
Sbjct: 255 DSKRRITVRNLRIREDIAKYLRNLDPNSAYYDPKTRAMRENPYA---NAGKNPDEVSYAG 311
Query: 73 --FFTWSPDTAPVRSKMVYA-----------SSKDALRRALNGVSSDIQGTDFSEVAYES 119
F ++ DT + ++A D + L S ++ DF E ES
Sbjct: 312 DNFVRYTGDTISMAQTQLFAWEAYDKGSEVHLQADPTKLELLYKSFKVKKEDFKEQQKES 371
Query: 120 VLEK 123
+LEK
Sbjct: 372 ILEK 375
>CE26678 [L] KOG0221 Mismatch repair ATPase MSH5 (MutS family)
Length = 1369
Score = 28.1 bits (61), Expect = 3.2
Identities = 19/81 (23%), Positives = 34/81 (41%), Gaps = 6/81 (7%)
Query: 1 MNAFNDLKLGKKYKFILYALNDSKTEIIVKETSAEQDYDKFLEQLPENDCLYAVYDFEYE 60
+ ND+ +++F+ ++D K +I+ S + ++ KFL Y + YE
Sbjct: 87 LKIMNDISEDLEFRFLKRLIDDVKPTLIIANRSQDLEFIKFL------TTRYDPQEKIYE 140
Query: 61 LGNNEGKRSKIVFFTWSPDTA 81
G E S+ TW A
Sbjct: 141 DGTTEEGTSEDTVPTWDSSLA 161
>At1g67250 [O] KOG3061 Proteasome maturation factor
Length = 141
Score = 28.1 bits (61), Expect = 3.2
Identities = 18/35 (51%), Positives = 23/35 (65%), Gaps = 2/35 (5%)
Query: 94 DALRRALNGVSSDIQGTDFSEVAYESVLEKVSRAA 128
DALR L+GV S+I G+ E +YES EK S+ A
Sbjct: 17 DALRFGLHGVKSNIIGSHPLESSYES--EKKSKEA 49
>At5g38650 [O] KOG3061 Proteasome maturation factor
Length = 141
Score = 27.7 bits (60), Expect = 4.1
Identities = 15/26 (57%), Positives = 17/26 (64%)
Query: 94 DALRRALNGVSSDIQGTDFSEVAYES 119
DALR L+GV SDI + E AYES
Sbjct: 17 DALRFGLHGVKSDILRSHPLETAYES 42
>At4g25180 [K] KOG3122 DNA-directed RNA polymerase III subunit
Length = 295
Score = 27.7 bits (60), Expect = 4.1
Identities = 20/74 (27%), Positives = 34/74 (45%), Gaps = 1/74 (1%)
Query: 37 DYDKFLEQLPENDCLYAVYDFEYELGNNEGKRSKIVFFTWS-PDTAPVRSKMVYASSKDA 95
D ++F E D + ELG + SK F + PD PV + A++K +
Sbjct: 117 DQEEFGEVAKNRDYDENTINSAEELGLTSVQHSKKQMFIFKIPDCLPVVKQTTGATTKRS 176
Query: 96 LRRALNGVSSDIQG 109
+R +G+S+ +G
Sbjct: 177 VREYSSGISNPFEG 190
>7296270 [T] KOG1997 PH domain-containing protein
Length = 1782
Score = 27.7 bits (60), Expect = 4.1
Identities = 20/68 (29%), Positives = 28/68 (40%), Gaps = 3/68 (4%)
Query: 49 DCLYAVYDFEYELGNNEGKRSKIVFFTWSPDTAPVRSKMVYASSKDALRRALNGVSSDIQ 108
+C+ Y+L N R+ F W D P RS+ A K L S I+
Sbjct: 1349 ECIRGTNSARYDLINRRKDRNSTEKFRWRKDQMPYRSQYADAVGKSEHELEL---SHFIE 1405
Query: 109 GTDFSEVA 116
G+ +EVA
Sbjct: 1406 GSLATEVA 1413
>Hs20544189_1 [TW] KOG1225 Teneurin-1 and related extracellular matrix proteins
contain EGF-like repeats
Length = 4057
Score = 27.7 bits (60), Expect = 4.1
Identities = 12/19 (63%), Positives = 14/19 (73%)
Query: 6 DLKLGKKYKFILYALNDSK 24
DL+ GKKYKF+LY L K
Sbjct: 3551 DLEPGKKYKFLLYGLLGGK 3569
>CE23294 [KL] KOG4439 RNA polymerase II transcription termination factor
TTF2/lodestar DEAD-box superfamily
Length = 540
Score = 26.9 bits (58), Expect = 7.0
Identities = 22/70 (31%), Positives = 35/70 (49%), Gaps = 8/70 (11%)
Query: 23 SKTEIIVKETSAEQDYDKFLEQLPEND-CLYAVYDFEY-----ELGNNEGKRSKIVFFTW 76
S T IIV + Q YD+F ++L EN +Y YD E+ + +E ++ +V T+
Sbjct: 102 SPTLIIVPKRIIYQWYDEFKDRLEENALSVYLYYDDEFSEARKNISASELQKYDVVLTTY 161
Query: 77 SPDTAPVRSK 86
PV+ K
Sbjct: 162 R--NVPVKEK 169
>YOR326w [Z] KOG0160 Myosin class V heavy chain
Length = 1574
Score = 26.6 bits (57), Expect = 9.2
Identities = 10/35 (28%), Positives = 20/35 (56%)
Query: 13 YKFILYALNDSKTEIIVKETSAEQDYDKFLEQLPE 47
Y F+++ALN TE K +++Y +++ + E
Sbjct: 1259 YSFVVFALNSILTEETFKNGMTDEEYKEYVSLVTE 1293
>Hs7661700 [T] KOG4225 Sorbin and SH3 domain-containing protein
Length = 816
Score = 26.6 bits (57), Expect = 9.2
Identities = 19/71 (26%), Positives = 34/71 (47%), Gaps = 8/71 (11%)
Query: 57 FEYELGN-----NEGKRSKIVFFTWSPDTAPVRSKMVYASSKDALRRALNGVSSDIQGTD 111
+EY+ G NE S I + +P+ + +Y+S+ A++R +G D+ +
Sbjct: 458 YEYQPGKSSVLTNEKMSSAI---SPTPEISSETPGYIYSSNFHAVKRESDGAPGDLTSLE 514
Query: 112 FSEVAYESVLE 122
Y+SVLE
Sbjct: 515 NERQIYKSVLE 525
>CE09014 [T] KOG0789 Protein tyrosine phosphatase
Length = 346
Score = 26.6 bits (57), Expect = 9.2
Identities = 13/41 (31%), Positives = 24/41 (57%), Gaps = 1/41 (2%)
Query: 5 NDLKLGKKYKFILYA-LNDSKTEIIVKETSAEQDYDKFLEQ 44
N ++ +Y F+ LN + + +++ET ++ YD FLEQ
Sbjct: 300 NSIQTDAQYLFVHQVILNYFRKKKLMEETGVQEAYDAFLEQ 340
>7303332 [S] KOG3528 FOG: PDZ domain
Length = 251
Score = 26.6 bits (57), Expect = 9.2
Identities = 13/53 (24%), Positives = 30/53 (56%), Gaps = 1/53 (1%)
Query: 20 LNDSKTEIIVKETSAEQDYDKFLEQLPENDCLYAVYDFEYELGNNEGKRSKIV 72
L+D E+++ E S ++ D+ ++LP + + + F E+G+N+ R+ +
Sbjct: 186 LDDEGNEVVI-ELSEDESSDEEEQELPHHRIIRNIRRFFAEVGDNQELRTNTI 237
Database: KOG eukaryal database 04/03
Posted date: Apr 14, 2003 1:07 PM
Number of letters in database: 30,389,216
Number of sequences in database: 60,738
Lambda K H
0.314 0.131 0.365
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 7,376,893
Number of Sequences: 60738
Number of extensions: 290849
Number of successful extensions: 691
Number of sequences better than 10.0: 59
Number of HSP's better than 10.0 without gapping: 43
Number of HSP's successfully gapped in prelim test: 16
Number of HSP's that attempted gapping in prelim test: 601
Number of HSP's gapped (non-prelim): 71
length of query: 131
length of database: 30,389,216
effective HSP length: 94
effective length of query: 37
effective length of database: 24,679,844
effective search space: 913154228
effective search space used: 913154228
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.9 bits)