ORF STATUS Function Best COG Functional category Pathways and functional systems
r_klactV0111 good E KOG1287 Amino acid transport and metabolism Amino acid transporters
Only best alignment is shown:
BLASTP 2.2.3 [May-13-2002]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= r_klactV0111 37469 39073 535
(535 letters)
Database: KOG eukaryal database 04/03
60,738 sequences; 30,389,216 total letters
Searching..................................................done
Color Key for Alignment Scores: 
Score E
Sequences producing significant alignments: (bits) Value
YHL036w [E] KOG1287 Amino acid transporters 430 e-120
YGR055w [E] KOG1287 Amino acid transporters 157 4e-38
Hs7657591 [E] KOG1287 Amino acid transporters 107 6e-23
7292991 [E] KOG1287 Amino acid transporters 94 7e-19
Hs9790235 [E] KOG1287 Amino acid transporters 85 3e-16
CE03266 [E] KOG1287 Amino acid transporters 84 4e-16
7294339 [E] KOG1287 Amino acid transporters 84 5e-16
7302046 [E] KOG1287 Amino acid transporters 82 2e-15
CE22438 [E] KOG1287 Amino acid transporters 79 2e-14
CE07028 [E] KOG1287 Amino acid transporters 78 3e-14
CE28440 [E] KOG1287 Amino acid transporters 78 4e-14
Hs7657683 [E] KOG1287 Amino acid transporters 77 5e-14
Hs6912670 [E] KOG1287 Amino acid transporters 77 7e-14
Hs21361563 [E] KOG1287 Amino acid transporters 74 4e-13
Hs19923170 [E] KOG1287 Amino acid transporters 74 6e-13
HsM4507055 [E] KOG1287 Amino acid transporters 74 7e-13
CE07491 [E] KOG1287 Amino acid transporters 69 1e-11
7301546 [E] KOG1287 Amino acid transporters 69 2e-11
CE17028 [E] KOG1287 Amino acid transporters 61 4e-09
CE17868 [E] KOG1287 Amino acid transporters 55 3e-07
>YHL036w [E] KOG1287 Amino acid transporters
Length = 546
Score = 430 bits (1106), Expect = e-120
Identities = 207/495 (41%), Positives = 307/495 (61%), Gaps = 9/495 (1%)
Query: 39 EVPQGRHLGIFSTVILFVSRIVGGGIYSVPSSVFVNCGGNVSLFLFVWLCAAVMAFIGMS 98
EVPQGRHLG+FSTV+LFVSRI+G GI++VPS + +N GGN ++ +W+ +A +AF G+
Sbjct: 58 EVPQGRHLGVFSTVVLFVSRIMGSGIFAVPSVILLNTGGNKLIYFAIWVFSAAIAFAGLY 117
Query: 99 MFLELGTILPKSGGRKNFLEFLYDKPPMMTTVILCTYCLMTCFAMSPAMILGKYILYALG 158
+FLE G+ +PKSGGRKNFLE +++P ++ +V+ Y ++T +A++ +++ GKY+L A G
Sbjct: 118 LFLEFGSWIPKSGGRKNFLERSFERPRLLISVVFSCYSVLTGYALTGSIVFGKYVLSAFG 177
Query: 159 YGEDFVNKESYASNYIGIAAIMVIVFVHGLSLNHGLIIQNXXXXXXXXXXXXMSLAGMYV 218
+D +K Y+ I+ I+ V +HG+S+ HG+ IQN M AG+Y
Sbjct: 178 VTDDSWSK------YVSISFIIFAVLIHGVSVRHGVFIQNALGGLKLIMIVLMCFAGLY- 230
Query: 219 TLFYHNASYDITQPSLLFXXXXXXXXXXXXXXXXXXFIQCFYCFAGWDTVHTVTSEIKDP 278
TLF++ ++ + L FI F+CF+GWDTVHTVTSEIK+P
Sbjct: 231 TLFFYKSTGQVAWD--LPVTQVEKDSLLSVSSIATAFISSFFCFSGWDTVHTVTSEIKNP 288
Query: 279 NRTLKLAGPLSLLMALICYLSLNIAYIKVLTYEEIKNAGPLLGSVLFSKIFGKAVGAQFX 338
+TLK++GPLSL++ +CY +N+AY+KVLTYEEI +AGPL+GSVLF+K+FG VG +F
Sbjct: 289 VKTLKVSGPLSLIICFVCYTMMNVAYLKVLTYEEIVSAGPLVGSVLFTKLFGPRVGGKFI 348
Query: 339 XXXXXXXXXXXXFVTVYGISRMNQEIFREGLFPFSAQLARNWPCNSPLPSLLICGIVSSF 398
V +Y ISR+NQEIF+EG PFS +++NWP ++PLPS+ +CG ++
Sbjct: 349 AFSIAISAASNILVVIYSISRVNQEIFKEGYLPFSIHMSKNWPFDAPLPSISLCGFITIA 408
Query: 399 WLYLLPGTGAAFDYLINFEGYGNQIMXXXXXXXXXXXXXXXKRYQFPSRTPIVGVVAFLL 458
W+ +LP G +F+YL++ +GYGNQ K R GV+A +
Sbjct: 409 WILILPKEGESFNYLVSMDGYGNQFFLLLVAIGLFIWRFKHKNEVPEIRASTFGVLAIIT 468
Query: 459 LSVYLSVGPFFGNGTGNSVGKFPSYQYAAIFLFALSVGFWFMKFVLLPRLFKYTLRSTVV 518
LS+Y+ + PFF + + N VG P YQ ++ + FW +KFVLLP+ F Y L +
Sbjct: 469 LSLYMLMAPFFADPSLNRVGFLPPYQIMSLLVIVACFFFWLVKFVLLPKFFHYKLLPKIT 528
Query: 519 VQNDGLTVVDWRRHP 533
+DGL V +W + P
Sbjct: 529 YLHDGLIVTEWVKKP 543
>YGR055w [E] KOG1287 Amino acid transporters
Length = 574
Score = 157 bits (397), Expect = 4e-38
Identities = 131/500 (26%), Positives = 217/500 (43%), Gaps = 24/500 (4%)
Query: 39 EVPQG-RHLGIFSTVILFVSRIVGGGIYSVPSSVFVNCGGNVSLFLFVWLCAAVMAFIGM 97
E+ QG + LGI S + L +R++G G+++V S+++ CG +V L L +W A++A G+
Sbjct: 53 ELDQGEKQLGILSCIGLICNRMLGTGVFAVSSTIYTLCG-SVGLALIMWAVGAIIAISGL 111
Query: 98 SMFLELGTILPKSGGRKNFLEFLYDKPPMMTTVILCTYCLMTCFAMSPAMILGKYILYAL 157
+++E GT +PK+GG KN+LE ++ KP T + Y +A ++ L A
Sbjct: 112 YVYMEFGTAIPKNGGEKNYLEAIFRKPKFFITCMYAAYIFFLGWAAGNSINTAIMFLTA- 170
Query: 158 GYGEDFVNKESYASNYIGIAAIMVIVFVHGLSLNHGLIIQNXXXXXXXXXXXXMSLAGMY 217
+ V K + IG+A + ++ L++ GL +QN +S+ G +
Sbjct: 171 --ADTEVTK--WNQRGIGVAVVFFAFLINSLNVKIGLYLQNILGIFKIGIVLFISITG-W 225
Query: 218 VTLFYHNASYDITQPSLLFXXXXXXXXXXXXXXXXXXFIQCFYCFAGWDTVHTVTSEIKD 277
V L S F + F G+ V+ E+K+
Sbjct: 226 VAL---GGGLKDGYQSHNFRNAFEGTETATAYGIVNALYSVIWSFVGYSNVNYALGEVKN 282
Query: 278 PNRTLKLAGPLSLLMALICYLSLNIAYIKVLTYEEIKNAGPLLGSVLFSKIFGKAVGAQF 337
P RTLK+AGP S++ I Y+ +NIAY V+ +++ ++ +L + F +FG +
Sbjct: 283 PVRTLKIAGPTSMVFLAIIYIFVNIAYFAVVPKDKLISSKLILAADFFDIVFG-GQAKRA 341
Query: 338 XXXXXXXXXXXXXFVTVYGISRMNQEIFREGLFPFSAQLARNWPCNSPLPSLLICGIVSS 397
++ R+ Q++ REG+ PFS A + P NSP+ L IV +
Sbjct: 342 AAALVGLSALGNVLSVIFSQGRIIQQLGREGVLPFSNFFASSKPFNSPMVGLFQHFIVCT 401
Query: 398 FWLYLLPGTGAAFDYLINFEGYGNQIMXXXXXXXXXXXXXXXKRYQFPSRTPI---VGVV 454
+ L P G A+ + N Y I+ ++ + PI V V
Sbjct: 402 VTI-LAPPPGDAYLLVQNLISYPMNIINFAISAGLLWIYWQRRQGKIEWNPPIKAGVFVT 460
Query: 455 AFLLLS-VYLSVGPFFGNGTGNSVGKFPSYQYAAIF---LFALSVGFWFMKFVLLPRLFK 510
F LS +YL + P+ G SV Y + +F ++ + LLPR
Sbjct: 461 GFFTLSNLYLIIAPYVPPSNGESVYSSMPYWIHCVIAWGIFFFGGVYYVVWAQLLPRWGH 520
Query: 511 YTLRSTVVVQNDGLTVVDWR 530
Y L S V+ DG WR
Sbjct: 521 YKLVSKDVLGEDGF----WR 536
>Hs7657591 [E] KOG1287 Amino acid transporters
Length = 487
Score = 107 bits (266), Expect = 6e-23
Identities = 106/471 (22%), Positives = 182/471 (38%), Gaps = 54/471 (11%)
Query: 44 RHLGIFSTVILFVSRIVGGGIYSVPSSVFVNCGGNVSLFLFVWLCAAVMAFIGMSMFLEL 103
+ LG+ S + + V I+G GI+ P SV N V L +W V+A +G F EL
Sbjct: 28 KELGLISGISIIVGTIIGSGIFVSPKSVLSNTEA-VGPCLIIWAACGVLATLGALCFAEL 86
Query: 104 GTILPKSGGRKNFLEFLYDKPPMMT------TVILCTYCLMTCFAMSPAMILGKYILYAL 157
GT++ KSGG +L Y P VI T + C + S + Y+
Sbjct: 87 GTMITKSGGEYPYLMEAYGPIPAYLFSWASLIVIKPTSFAIICLSFSEYVCAPFYV---- 142
Query: 158 GYGEDFVNKESYASNYIGIAAIMVIVFVHGLSLNHGLIIQNXXXXXXXXXXXXMSLAGMY 217
+ AAI+ I V+ LS+ G +QN + ++G+
Sbjct: 143 -----GCKPPQIVVKCLAAAAILFISTVNSLSVRLGSYVQNIFTAAKLVIVAIIIISGLV 197
Query: 218 VTLFYHNASYDITQPSLLFXXXXXXXXXXXXXXXXXXFIQCFYCFAGWDTVHTVTSEIKD 277
+ + ++D F + + GW+ ++ +T E+++
Sbjct: 198 LLAQGNTKNFD----------NSFEGAQLSVGAISLAFYNGLWAYDGWNQLNYITEELRN 247
Query: 278 PNRTLKLAGPLSLLMALICYLSLNIAYIKVLTYEEIKNAGPLLGSVLFSKIFGKAV---G 334
P R L LA + + + CY+ +N++Y V+T E LL S + FG V
Sbjct: 248 PYRNLPLAIIIGIPLVTACYILMNVSYFTVMTATE------LLQSQAVAVTFGDRVLYPA 301
Query: 335 AQFXXXXXXXXXXXXXFVTVYGISRMNQEIFREG--LFPFSAQLARNWPCNSPLPSLLIC 392
+ T + R+ REG L S R +P P+++
Sbjct: 302 SWIVPLFVAFSTIGAANGTCFTAGRLIYVAGREGHMLKVLSYISVRRL---TPAPAIIFY 358
Query: 393 GIVSSFWLYLLPGTGAAFDYLINFEGYGNQIMXXXXXXXXXXXXXXXKRYQFPSRTPIVG 452
GI+++ +Y++PG + L+N+ + + K + P + P+V
Sbjct: 359 GIIAT--IYIIPGD---INSLVNYFSFAAWLFYGLTILGLIVMRFTRKELERPIKVPVVI 413
Query: 453 VVAFLLLSVYLSVGPFFGNGTGNSVGKFPSYQYAAIFLFALSVGFWFMKFV 503
V L+SV+L + P P+++Y LF LS ++ FV
Sbjct: 414 PVLMTLISVFLVLAPIISK---------PTWEYLYCVLFILSGLLFYFLFV 455
>7292991 [E] KOG1287 Amino acid transporters
Length = 445
Score = 93.6 bits (231), Expect = 7e-19
Identities = 104/460 (22%), Positives = 182/460 (38%), Gaps = 38/460 (8%)
Query: 59 IVGGGIYSVPSSVFVNCGGNVSLFLFVWLCAAVMAFIGMSMFLELGTILPKSGGRKNFLE 118
++G GI+ PS + V G +V + +WL V++ +G + ELGT+ SG +
Sbjct: 1 MIGSGIFVSPSGLLVRTG-SVGVSFIIWLACGVLSLLGALAYAELGTMNTSSGAEWAYFM 59
Query: 119 FLYDKPPMMTTVILCTYCLMTCFAMSPAMILGKYILYALGYGEDFVNKESYASNYIGIAA 178
Y P + T L A+I + YA+ + + + A
Sbjct: 60 DAYGPAPAFLFSWVSTLVLKPS---QMAIICLSFAQYAVEAFVTECDPPRGVVKMVALVA 116
Query: 179 IMVIVFVHGLSLNHGLIIQNXXXXXXXXXXXXMSLAGMYVTLFYHNASYDITQPSLLFXX 238
I++I+FV+ S+N G+ +QN + G ++ + Q +
Sbjct: 117 IVMILFVNCYSVNLGMAVQNVFTAAKLVAVVVVICGG----------AWKLMQGNTQHLS 166
Query: 239 XXXXXXXXXXXXXXXXFIQCFYCFAGWDTVHTVTSEIKDPNRTLKLAGPLSLLMALICYL 298
F + + GW+ ++ VT EIK+P++ L + + + + +CY
Sbjct: 167 NAFNGPMPNVGAIATAFYTGLWAYDGWNNLNYVTEEIKNPSKNLPRSIIIGIPLVTLCYA 226
Query: 299 SLNIAYIKVLTYEEIKNAGPLLGSVLF-SKIFGKAVGAQFXXXXXXXXXXXXXFVTVYGI 357
+NI+Y+ ++ +E+ + + +V F ++I G A T++
Sbjct: 227 LINISYLAAMSPQEMIESEAV--AVTFGNRILGAL--AWLMPLSVTISTFGSANGTLFAA 282
Query: 358 SRMNQEIFREG--LFPFSAQLARNWPCNSPLPSLLICGIVSSFWLYLLPGTGAAFDYLIN 415
R+ REG L S R +P P L+ +++S +L GT D LI+
Sbjct: 283 GRLCFAASREGHLLDILSYVHVRRL---TPAPGLIFHSLIAS--AMVLHGT---IDSLID 334
Query: 416 FEGYGNQIMXXXXXXXXXXXXXXXKRYQFPSRTPIVGVVAFLLLSVYLSVGPFFGNGTGN 475
F + I Y P + PI+ V L++SVYL P F
Sbjct: 335 FFSFTAWIFYGGAMLALIVMRYTKPNYPRPYKVPIIIPVVVLVISVYLVAAPIFETPR-- 392
Query: 476 SVGKFPSYQYAAIFLFALSVGFW-FMKFVLLPRLF-KYTL 513
Y YA +F+FA + + F+K + PR K TL
Sbjct: 393 -----VEYLYALLFIFAGLIFYVPFVKLGMTPRFMNKVTL 427
>Hs9790235 [E] KOG1287 Amino acid transporters
Length = 523
Score = 84.7 bits (208), Expect = 3e-16
Identities = 86/384 (22%), Positives = 162/384 (41%), Gaps = 20/384 (5%)
Query: 44 RHLGIFSTVILFVSRIVGGGIYSVPSSVFVNCGGNVSLFLFVWLCAAVMAFIGMSMFLEL 103
+ +G+ S + + I+G GI+ P V + G+V L LFVW+ + +G + EL
Sbjct: 38 KEIGLLSACTIIIGNIIGSGIFISPKGVLEH-SGSVGLALFVWVLGGGVTALGSLCYAEL 96
Query: 104 GTILPKSGGRKNFLEFLYDKPPMMTTVILCTYCLMTCFAMSPAMILGKYILYALGYGEDF 163
G +PKSGG ++ ++ + +L ++ + S A+I + Y L
Sbjct: 97 GVAIPKSGGDYAYVTEIFGG---LAGFLLLWSAVLIMYPTSLAVISMTFSNYVLQPVFPN 153
Query: 164 VNKESYASNYIGIAAIMVIVFVHGLSLNHGLIIQNXXXXXXXXXXXXMSLAGMYVTLFYH 223
+ AS + +A +M++ +V+ S+ IQ+ + G+ H
Sbjct: 154 CIPPTTASRVLSMACLMLLTWVNSSSVRWATRIQDMFTGGKLLALSLIIGVGLLQIFQGH 213
Query: 224 NASYDITQPSLLFXXXXXXXXXXXXXXXXXXFIQCFYCFAGWDTVHTVTSEIKDPNRTLK 283
++ +PS F F+Q + F+GW+ ++ VT E+ D + L
Sbjct: 214 ---FEELRPSNAFAFWMTPSVGHLALA----FLQGSFAFSGWNFLNYVTEEMVDARKNLP 266
Query: 284 LAGPLSLLMALICYLSLNIAYIKVLTYEEIKNAGPLLGSVLF-SKIFGKAVGAQFXXXXX 342
A +S+ + Y NIAY ++ +E+ ++ + +V F K+ G
Sbjct: 267 RAIFISIPLVTFVYTFTNIAYFTAMSPQELLSSNAV--AVTFGEKLLGYFSWVMPVSVAL 324
Query: 343 XXXXXXXXFVTVYGISRMNQEIFREGLFPFSAQLARNWPCNSPLPSLLICGIVSSFWLYL 402
++ Y SR+ REG P + C +P+P+LL+C ++ + L
Sbjct: 325 STFGGINGYLFTY--SRLCFSGAREGHLPSLLAMIHVRHC-TPIPALLVCCGATAV-IML 380
Query: 403 LPGTGAAFDYL--INFEGYGNQIM 424
+ T +Y+ IN+ YG I+
Sbjct: 381 VGDTYTLINYVSFINYLCYGVTIL 404
>CE03266 [E] KOG1287 Amino acid transporters
Length = 493
Score = 84.3 bits (207), Expect = 4e-16
Identities = 95/483 (19%), Positives = 189/483 (38%), Gaps = 62/483 (12%)
Query: 44 RHLGIFSTVILFVSRIVGGGIYSVPSSVFVNCGGNVSLFLFVWLCAAVMAFIGMSMFLEL 103
+ L +F+ V + V I+G GI+ P+ V G +V L L VWL + + IG + EL
Sbjct: 30 KSLTLFNGVSMIVGCIIGSGIFVSPTGVQEQAG-SVGLSLIVWLISGIFTAIGAYCYAEL 88
Query: 104 GTILPKSGGRKNFLEFLYDKPPMMTTV------ILCTYCLMTCFAMSPAMILGKYILYAL 157
GT++ KSGG ++ + P + + I+ C +T A++ + +Y L
Sbjct: 89 GTLIKKSGGDYAYIMEAFG--PFVAFIRLWIEAIVVRPCTVTIVALT-------FAIYGL 139
Query: 158 GYGEDFVNKESYASNYIGIAAIMVIVFVHGLSLNHGLIIQNXXXXXXXXXXXXMSLAGMY 217
+ + I I+++ ++ +S+ I+Q+ + L G+
Sbjct: 140 RPFFPDCAPPDVVAELLAILLIVLMTAINCISVRLATIVQDWFTIAKVVALCLIILTGLG 199
Query: 218 VTLF------------YHNASYDITQPSLLFXXXXXXXXXXXXXXXXXXFIQCFYCFAGW 265
+ F + N S D T+ SL F + ++GW
Sbjct: 200 LLFFGESQYKDSFENIFENTSQDFTKVSLAFYSG-------------------LFAYSGW 240
Query: 266 DTVHTVTSEIKDPNRTLKLAGPLSLLMALICYLSLNIAYIKVLTYEEIKNAGPLLGSVLF 325
+ ++ + E+++P R L LA +S+ + Y+ N+A ++ +E+ + P + +
Sbjct: 241 NFLNFIVEELQNPKRNLPLAIAISITSCTVIYVLTNVALYTAISPDEMLES-PAVAVLFA 299
Query: 326 SKIFGKAVGAQFXXXXXXXXXXXXXFVTVYGISRMNQEIFREGLFPFSAQLARNWPCNSP 385
+K++GK A ++ +R+ REG P + N +P
Sbjct: 300 NKLYGKF--AFIMPLCVACSTIGSANGVIFTSARLFYSGAREGQMPAVLTMI-NKKTKTP 356
Query: 386 LPSLLICGIVSSFWLYLLPGTGAAFDYLINFEGYGNQIMXXXXXXXXXXXXXXXKRYQFP 445
+P++++ G +S YLL LIN+ + P
Sbjct: 357 IPAVILTGALSI--AYLLASKDVY--QLINYIQISYWLAIGTAIAALFWLRRTMPDASRP 412
Query: 446 SRTPIVGVVAFLLLSVYLSVGPFFGNGTGNSVGKFPSYQYAAIFLFALSVGF-----WFM 500
+ P++ FL + L + P +G +A+ ++ + +G+ WF
Sbjct: 413 IKVPLIWPAIFLAGCIALVLIPMVAAPRDTGIGLL--IMLSAVPVYGIFIGWKNKPKWFN 470
Query: 501 KFV 503
+F+
Sbjct: 471 EFI 473
>7294339 [E] KOG1287 Amino acid transporters
Length = 499
Score = 84.0 bits (206), Expect = 5e-16
Identities = 88/427 (20%), Positives = 169/427 (38%), Gaps = 33/427 (7%)
Query: 44 RHLGIFSTVILFVSRIVGGGIYSVPSSVFVNCGGNVSLFLFVWLCAAVMAFIGMSMFLEL 103
+ +G+ V + V IVG GI+ P V + G++ L VW+ + V++ +G + EL
Sbjct: 41 KQIGLLDGVAIIVGVIVGSGIFVSPKGV-LKFSGSIGQSLIVWVLSGVLSMVGALCYAEL 99
Query: 104 GTILPKSGGRKNFLEFLYDKPPMMTTVILCTYCLMTCFAMSPAMILGKYILYALGYGEDF 163
GT++PKSGG ++ + P + + L+ A+ Y+L D
Sbjct: 100 GTMIPKSGGDYAYIGTAFGPLPAFLYLWVALLILVPTGNAITALTFAIYLLKPFWPSCDA 159
Query: 164 VNKESYASNYIGIAAIMVIVFVHGLSLNHGLIIQNXXXXXXXXXXXXMSLAGMYVTLFYH 223
+ A + A I V+ ++ ++ + + + AG++ +
Sbjct: 160 PIE---AVQLLAAAMICVLTLINCYNVKWVTRVTDIFTGTKVVALLVIVGAGVWWLFDGN 216
Query: 224 NASYDITQPSLLFXXXXXXXXXXXXXXXXXXFIQCFYCFAGWDTVHTVTSEIKDPNRTLK 283
+D F + ++GW+ ++ VT E+KDP R L
Sbjct: 217 TEHWD----------NPFSGGLQDPGYIALAFYSGLFSYSGWNYLNFVTEELKDPYRNLP 266
Query: 284 LAGPLSLLMALICYLSLNIAYIKVLTYEEIKNAGPLLGSVLFSKIFG-KAVGAQFXXXXX 342
A +S+ + + Y+ NIAY VL+ +EI L S + FG K +G +
Sbjct: 267 KAICISMPVVTVIYMITNIAYFSVLSPDEI------LSSDAVAVTFGDKMLG--YMSWIM 318
Query: 343 XXXXXXXXFVTVYGISRMNQEIF----REGLFPFSAQLARNWPCNSPLPSLLICGIVSSF 398
F ++ G + +F R G P + L N C +P+PSL+ G+++
Sbjct: 319 PFAVACSTFGSLNGAIFASSRLFFVGARNGHLPAAISLI-NVNCLTPVPSLIFLGVLTLL 377
Query: 399 WLYLLPGTGAAFDYLINFEGYGNQIMXXXXXXXXXXXXXXXKRYQFPSRTPIVGVVAFLL 458
L++ LIN+ Y + + + P + + + +L+
Sbjct: 378 LLFI-----EDVYVLINYVSYVEALFTLISVSGLLWMRYKQPKTERPIKVNLALPIIYLI 432
Query: 459 LSVYLSV 465
+ ++L +
Sbjct: 433 VCLFLVI 439
>7302046 [E] KOG1287 Amino acid transporters
Length = 505
Score = 82.0 bits (201), Expect = 2e-15
Identities = 91/475 (19%), Positives = 185/475 (38%), Gaps = 46/475 (9%)
Query: 39 EVPQGRHLGIFSTVILFVSRIVGGGIYSVPSSVFVNCGGNVSLFLFVWLCAAVMAFIGMS 98
EV + + + + V I+G GI+ P+ V + G +V+L L VW+ + + + +G
Sbjct: 42 EVTLKAKMSLLNGCTVIVGSIIGSGIFVSPTGVLMYTG-SVNLALIVWVISGLFSMVGAY 100
Query: 99 MFLELGTILPKSGGRKNFLEFLYDKPPMMTTVILCTYCLMT--CFAMSPAMILGKYILYA 156
+ ELGT++ KSG ++ + P M + L C++ C A+ Y+L
Sbjct: 101 CYAELGTMITKSGADYAYIMETFG--PFMAFIRLWIECMIVRPCSQAIVALTFSTYVLKP 158
Query: 157 LGYGEDFVNKESYASNYIGIAAIMVIVFVHGLSLNHGLIIQNXXXXXXXXXXXXMSLAGM 216
+ E ++S + + + I+V+ ++ + +Q+ + G+
Sbjct: 159 F-FPECTPPEDS--ARLLAVCCILVLTLINCWDVKWATAVQDIFTYAKLLALFIIIATGV 215
Query: 217 YVTLFYHNASYDITQPSLLFXXXXXXXXXXXXXXXXXXFIQCFYCFAGWDTVHTVTSEIK 276
Y L+ N Y F + + GW+ ++ + E+K
Sbjct: 216 Y-QLYLGNTQY-----------FTFENTDTKVTSIALSFYSGLFAYNGWNYLNFIIEELK 263
Query: 277 DPNRTLKLAGPLSLLMALICYLSLNIAYIKVLTYEEIKNAGPLLGSVLFSKIFGKAVGAQ 336
DP + L A +S + I Y+ N+++ +L+ +E+ + + +V +++ +A G
Sbjct: 264 DPVKNLPRAIAISCTLVTIVYVMANVSFYTILSPDEVMGSSAV--AVTYAE---RAFG-- 316
Query: 337 FXXXXXXXXXXXXXFVTVYGISRMNQEIF----REGLFP---FSAQLARNWPCNSPLPSL 389
F V GI + +F G P Q+ R +P P++
Sbjct: 317 MLAWTIPVFVALSTFGAVNGILLTSSRLFYAGANNGQMPEILTMIQIQR----FTPTPAV 372
Query: 390 LICGIVSSFWLYLLPGTGAAFDYLINFEGYGNQIMXXXXXXXXXXXXXXXKRYQFPSRTP 449
L ++S +L T + LIN+ G+ + P R P
Sbjct: 373 LAMALLSMLYL-----TVSDIFALINYVGFATWLSIGVAVLCLPWLRWAQPNLPRPIRVP 427
Query: 450 IVGVVAFLLLSVYLSVGPFFGNGTGNSVG---KFPSYQYAAIFLFALSVGFWFMK 501
+V + +L+ +++++V P + + G S +F+ + WF K
Sbjct: 428 MVFPIVYLIATIFVTVVPMYASPVETGYGILMILSSIPVYLVFIAWKNKPIWFQK 482
>CE22438 [E] KOG1287 Amino acid transporters
Length = 541
Score = 78.6 bits (192), Expect = 2e-14
Identities = 119/538 (22%), Positives = 206/538 (38%), Gaps = 108/538 (20%)
Query: 30 NVSSLISDNEVPQGRH-LGIFSTVILFVSRIVGGGIYSVPSSVFVNCGGNVSLFLFVWLC 88
++ L + +V RH +G++S + ++ I+G GI+ P +V N + L VWL
Sbjct: 3 SIEDLPTVGDVAATRHQMGLWSCMSYVIANIIGAGIFITPGTVLKLALTN-GMALVVWLG 61
Query: 89 AAVMAFIGMSMFLELGTILPKSGGRKNFLEFLYDKPPMMTTVILCTYCLMTCFAMSPAMI 148
+++ IG ++ELGT + G + ++ + + + + A A
Sbjct: 62 CGLISLIGGICYIELGTSIRDPGCDFAYNVYVGWEGIAFSFMWVGVIMSFPASAAVQAQT 121
Query: 149 LGKYI------LYALGYGEDFVNKESYASNYIGIAAIMVIVFVHGLSLNHGLIIQNXXXX 202
G+YI ++ LG D + + +G A I+++ ++ +++
Sbjct: 122 FGQYIVAGLSPIWHLGSPYDVILERG-----LGFALIIILTVLNLYAIDK----YASKFQ 172
Query: 203 XXXXXXXXMSLAGMYVTLFYH------------------NASYDITQPSLLFXXXXXXXX 244
+SLA + VT F++ N YDI Q SL F
Sbjct: 173 IFVTIAKLLSLAIIIVTGFWYLIVKGETEHFKDAFTPLPNEKYDIGQISLAFYGA----- 227
Query: 245 XXXXXXXXXXFIQCFYCFAGWDTVHTVTSEIKDPNRTLKLAGPLSLLMALICYLSLNIAY 304
+ FAGWD ++ T EIK+P RT+ +A + + Y+++N++Y
Sbjct: 228 --------------LWSFAGWDILNYGTPEIKNPRRTMPIALLGGISAVTLVYMAMNVSY 273
Query: 305 IKVLTYEEIKNAGPLLGSVLFSKIFGKAVGAQFXXXXXXXXXXXXXF-VTVYGISRMNQE 363
+ VL E +KN+ AV A F F +++ I +N
Sbjct: 274 MTVLDTETLKNS--------------SAVAADFARITLGDFSYAIPFMISILLIGTLNSN 319
Query: 364 IF----------REGLFPFSAQLARNWPCNSPLPSL---LICGIVSSFWLYLLPGTGAAF 410
IF REG P N NSP +L LIC I +F T +
Sbjct: 320 IFCGSRFTHAAAREGHLPTFLSCI-NAESNSPRAALLFQLICTIAVTF-----VDTESLI 373
Query: 411 DYLINFEGYGNQIMXXXXXXXXXXXXXXXKRYQFPSRTPIVGVVAFLLLSVYLSVGPFFG 470
Y + F +G ++ + R P++ + F ++++ L V PF
Sbjct: 374 TY-VTFVMFGQRVFTMAALLWIRYRNIPV--HPDAIRVPLIFSILFFMITIALVVTPFIE 430
Query: 471 NGTGNSVGKFPSYQYAAIFLFALSVGFWFMKFVLLPR-LFKYTLRSTVVVQNDGLTVV 527
+ T VG + L + FMK LP L+++ NDG+T V
Sbjct: 431 DFTTTIVG-------VGLVLMGFLLYMIFMKPKQLPGFLYRF---------NDGITRV 472
>CE07028 [E] KOG1287 Amino acid transporters
Length = 464
Score = 78.2 bits (191), Expect = 3e-14
Identities = 91/440 (20%), Positives = 164/440 (36%), Gaps = 46/440 (10%)
Query: 35 ISDNEVPQGRHLGIFSTVILFVSRIVGGGIYSVPSSVFVNCGGNVSLFLFVWLCAAVMAF 94
+S N++ + +F+ + + I+G GI+ P V + G + + L +WL + V A
Sbjct: 8 VSLNQIKLKPRISLFNGCTIIIGVIIGSGIFVSPKGVLLEAG-SAGMSLLIWLLSGVFAM 66
Query: 95 IGMSMFLELGTILPKSGGRKNFLEFLYDKPPMMTTVILCTYCLMTCFAMSPAMILGKYIL 154
IG + ELGT++PKSGG ++Y+ + + + L+ S A+I
Sbjct: 67 IGAVCYSELGTLIPKSGGD---YAYIYEAFGPLPSFLFLWVALVIINPTSLAIIAITCAT 123
Query: 155 YALGYGEDFVN--KESYASNYIGIAAIMVIVFVHGLSLNHGLIIQNXXXXXXXXXXXXMS 212
YAL + F + N I V+ F++ + + +
Sbjct: 124 YAL---QPFYSCPVPDVVVNLFAGCIIAVLTFINCWDVRMATRTNDFFTITKLIALTLII 180
Query: 213 LAGMYVTLFYHNASYDITQPSLLFXXXXXXXXXXXXXXXXXXFIQCFYCFAGWDTVHTVT 272
G Y H ++ P + F + F+G+ ++ VT
Sbjct: 181 TCGGYWLSLGH--IDNLVMPDV------AEGSQTKLSAIAMAFYSGVFSFSGFSYLNFVT 232
Query: 273 SEIKDPNRTLKLAGPLSLLMALICYLSLNIAYIKVLTYEEIKNAGPLLGSVLFSKIFGKA 332
E+K+P R L A +S+ + I Y+ +NIAY VLT +EI ++ A
Sbjct: 233 EELKNPFRNLPRAIYISIPIVTIVYMLVNIAYFSVLTVDEILDS--------------DA 278
Query: 333 VGAQFXXXXXXXXXXXXXFVTVYGISRMNQEIFREGLFPFSAQLARNWPCNSPLPSLLIC 392
V F ++ N ++ QL +P+PSL+
Sbjct: 279 VAITFADKILGTFGSKILMPLMFFSGARNSQLPELFAMISIRQL-------TPIPSLIFL 331
Query: 393 GIVSSFWLYLLPGTGAAFDYLINFEGYGNQIMXXXXXXXXXXXXXXXKRYQF---PSRTP 449
G S L++ G F LIN+ + ++ P +
Sbjct: 332 GGTSIVMLFI----GNVFQ-LINYLSFAESLVVFSSVAGLLKLRFTMPENVLNARPIKIS 386
Query: 450 IVGVVAFLLLSVYLSVGPFF 469
++ + F L+ ++L + PFF
Sbjct: 387 LLWPILFFLMCLFLLILPFF 406
>CE28440 [E] KOG1287 Amino acid transporters
Length = 493
Score = 77.8 bits (190), Expect = 4e-14
Identities = 89/466 (19%), Positives = 183/466 (39%), Gaps = 30/466 (6%)
Query: 20 ERDSTEDLSKNVSSLISDNEVPQG---RHLGIFSTVILFVSRIVGGGIYSVPSSVFVNCG 76
+++ +E L++ S+ D EV + + +F+ V + V I+G GI+ P+ + G
Sbjct: 3 KQEQSEPLNQEPSNEHHDEEVGDKGLEKTMTLFNGVSIIVGCIIGSGIFISPTGIQAQAG 62
Query: 77 GNVSLFLFVWLCAAVMAFIGMSMFLELGTILPKSGGRKNFLEFLYDKPPMMTTVILCTYC 136
+V L L VW+ + + A IG + ELGT++ KSGG ++ + + + +
Sbjct: 63 -SVGLSLIVWVLSGLFAGIGAFCYAELGTLIRKSGGDYAYIMEAFGPFLAFLRLWIESIV 121
Query: 137 LMTCFAMSPAMILGKYILYALGYGEDFVNKESYASNYIGIAAIMVIVFVHGLSLNHGLII 196
+ C A A+ Y+L Y + + ++ I ++++ V+ +S+ +
Sbjct: 122 VRPCTATIVALTFAIYMLKPF-YPD--CDSPPLSTELIAALLLVLLTAVNCISVKWASKV 178
Query: 197 QNXXXXXXXXXXXXMSLAGMYVTLFYHNASYDITQPSLLFXXXXXXXXXXXXXXXXXXFI 256
Q+ + G++ + ++D + F
Sbjct: 179 QDFFFVTKTAALVLIIFTGLWNMVSGKPEAFDSFE-------NIFENTAKDLETASLAFY 231
Query: 257 QCFYCFAGWDTVHTVTSEIKDPNRTLKLAGPLSLLMALICYLSLNIAYIKVLTYEEIKNA 316
+ + GW+ ++ + E+++P R L L+ +S + I Y N+A +T +E+ A
Sbjct: 232 SGLFAYQGWNYLNFIVEELQNPKRNLPLSIAISCSLCTIIYTLTNVALYTSITPDEML-A 290
Query: 317 GPLLGSVLFSKIFGKAVGAQFXXXXXXXXXXXXXFVTVYGISRMNQEIF----REGLFPF 372
P + + K +G + + G+ + +F REG P
Sbjct: 291 SPAVAVLFAEKNYG------WFAFCMPIFVACSTIGSANGVILTSSRLFYCGAREGQMPN 344
Query: 373 SAQLARNWPCNSPLPSLLICGIVSSFWLYLLPGTGAAFDYLINFEGYGNQIMXXXXXXXX 432
+ N +P+P++++ G++S +L L + LIN+ I
Sbjct: 345 VLTMV-NKTTKTPIPAVILTGLLSLLYLLLSNNIYS----LINYIQVSYWIAIGGAILAL 399
Query: 433 XXXXXXXKRYQFPSRTPIVGVVAFLLLSVYLSVGPFFGNGTGNSVG 478
+ PIV + F + V L + P GN ++G
Sbjct: 400 FYFRKTMPDAPRAVKAPIVFPIIFFIGCVLLVLVPVLGNPKDTAIG 445
>Hs7657683 [E] KOG1287 Amino acid transporters
Length = 501
Score = 77.4 bits (189), Expect = 5e-14
Identities = 80/377 (21%), Positives = 147/377 (38%), Gaps = 31/377 (8%)
Query: 44 RHLGIFSTVILFVSRIVGGGIYSVPSSVFVNCGGNVSLFLFVWLCAAVMAFIGMSMFLEL 103
R + + V + + I+G GI+ P V N G +V + L +W V++ G + EL
Sbjct: 42 RKVTLLRGVSIIIGTIIGAGIFISPKGVLQNTG-SVGMSLTIWTVCGVLSLFGALSYAEL 100
Query: 104 GTILPKSGGRKNFLEFLYDKPPMMTTVILCTYCLMTCFAMSPAMILGKYILYALGYGEDF 163
GT + KSGG ++ ++ P V + + ++ G+YIL F
Sbjct: 101 GTTIKKSGGHYTYILEVFGPLPAFVRVWVELLIIRPAATAVISLAFGRYILEPF-----F 155
Query: 164 VNKE--SYASNYIGIAAIMVIVFVHGLSLNHGLIIQNXXXXXXXXXXXXMSLAGMYVTLF 221
+ E A I I V++ ++ +S++ IQ + + G+ +
Sbjct: 156 IQCEIPELAIKLITAVGITVVMVLNSMSVSWSARIQIFLTFCKLTAILIIIVPGVMQLIK 215
Query: 222 YHNASYDITQPSLLFXXXXXXXXXXXXXXXXXXFIQCFYCFAGWDTVHTVTSEIKDPNRT 281
++ F Y +AGW ++ VT E+++P +T
Sbjct: 216 GQTQNF----------KDAFSGRDSSITRLPLAFYYGMYAYAGWFYLNFVTEEVENPEKT 265
Query: 282 LKLAGPLSLLMALICYLSLNIAYIKVLTYEE--IKNAGPLLGSVLFSKIFGKAVGAQFXX 339
+ LA +S+ + I Y+ N+AY + EE + NA + S F AV
Sbjct: 266 IPLAICISMAIVTIGYVLTNVAYFTTINAEELLLSNAVAVTFSERLLGNFSLAVPIFVAL 325
Query: 340 XXXXXXXXXXXFVTVYGISRMNQEIFREGLFPFSAQLARNWPCNSPLPSLLICGIVSSFW 399
V+ +SR+ REG P + + ++PLP++++ ++
Sbjct: 326 SCFGSMNGG-----VFAVSRLFYVASREGHLPEILSMI-HVRKHTPLPAVIVLHPLTMIM 379
Query: 400 LYLLPGTGAAFDYLINF 416
L+ D L+NF
Sbjct: 380 LF-----SGDLDSLLNF 391
>Hs6912670 [E] KOG1287 Amino acid transporters
Length = 535
Score = 77.0 bits (188), Expect = 7e-14
Identities = 83/390 (21%), Positives = 155/390 (39%), Gaps = 40/390 (10%)
Query: 44 RHLGIFSTVILFVSRIVGGGIYSVPSSVFVNCGGNVSLFLFVWLCAAVMAFIGMSMFLEL 103
+ +G+ S + V I+G GI+ P V N G +V L L VW+ + +G + EL
Sbjct: 38 KEIGLVSACGIIVGNIIGSGIFVSPKGVLENAG-SVGLALIVWIVTGFITVVGALCYAEL 96
Query: 104 GTILPKSGGRKNFLEFLYDKPPMMTTVILCTYCLMTCFAMSPAMILGKYILYALGYGEDF 163
G +PKSGG ++++ ++ + + + A+ Y+L L + F
Sbjct: 97 GVTIPKSGGDYSYVKDIFGGLAGFLRLWIAVLVIYPTNQAVIALTFSNYVLQPL-FPTCF 155
Query: 164 VNKESYASNYIGIAAIMVIVFVHGLSLNHGLIIQNXXXXXXXXXXXXMSLAGM------- 216
+ + ++++ +V+ S+ +Q+ + + G+
Sbjct: 156 PPESGL--RLLAAICLLLLTWVNCSSVRWATRVQDIFTAGKLLALALIIIMGIVQICKGE 213
Query: 217 YVTLFYHNASYDITQPSLLFXXXXXXXXXXXXXXXXXXFIQCFYCFAGWDTVHTVTSEIK 276
Y L NA D +P + F+Q + + GW+ ++ VT E+
Sbjct: 214 YFWLEPKNAFEDFQEPDI--------------GLVALAFLQGSFAYGGWNFLNYVTEELV 259
Query: 277 DPNRTLKLAGPLSLLMALICYLSLNIAYIKVLTYEEIKNAGPLLGSVLFSKIFGK---AV 333
DP + L A +S+ + Y+ N+AY+ ++ +E LL S + FG+ V
Sbjct: 260 DPYKNLPRAIFISIPLVTFVYVFANVAYVTAMSPQE------LLASNAVAVTFGEKLLGV 313
Query: 334 GAQFXXXXXXXXXXXXXFVTVYGISRMNQEIFREGLFPFSAQLARNWPCNSPLPSLLICG 393
A +++ SR+ REG P + C +P+P+LL
Sbjct: 314 MAWIMPISVALSTFGGVNGSLFTSSRLFFAGAREGHLPSVLAMIHVKRC-TPIPALLFTC 372
Query: 394 IVSSFWLYLLPGTGAAFDYLINFEGYGNQI 423
I + LL + LIN+ G+ N +
Sbjct: 373 IST-----LLMLVTSDMYTLINYVGFINYL 397
>Hs21361563 [E] KOG1287 Amino acid transporters
Length = 511
Score = 74.3 bits (181), Expect = 4e-13
Identities = 88/440 (20%), Positives = 164/440 (37%), Gaps = 23/440 (5%)
Query: 39 EVPQGRHLGIFSTVILFVSRIVGGGIYSVPSSVFVNCGGNVSLFLFVWLCAAVMAFIGMS 98
+V + + + + V L V ++G GI+ P V + + L L +W + + G
Sbjct: 30 QVKLKKEISLLNGVCLIVGNMIGSGIFVSPKGVLIY-SASFGLSLVIWAVGGLFSVFGAL 88
Query: 99 MFLELGTILPKSGGRKNFLEFLYDKPPMMTTVILCTYCLMTCFAMSPAMILGKYILYALG 158
++ELGT + KSG ++ L + + L T L+ S A+I + Y +
Sbjct: 89 CYVELGTTIKKSGA--SYAYILEAFGGFLAFIRLWT-SLLIIEPTSQAIIAITFANYMVQ 145
Query: 159 YGEDFVNKESYASNYIGIAAIMVIVFVHGLSLNHGLIIQNXXXXXXXXXXXXMSLAGMYV 218
AS + A I ++ F++ + G ++Q+ + +AG+
Sbjct: 146 PLFPSCFAPYAASRLLAAACICLLTFINCAYVKWGTLVQDIFTYAKVLALIAVIVAGIV- 204
Query: 219 TLFYHNASYDITQPSLLFXXXXXXXXXXXXXXXXXXFIQCFYCFAGWDTVHTVTSEIKDP 278
+ Q + + ++GWDT++ VT EIK+P
Sbjct: 205 ---------RLGQGASTHFENSFEGSSFAVGDIALALYSALFSYSGWDTLNYVTEEIKNP 255
Query: 279 NRTLKLAGPLSLLMALICYLSLNIAYIKVLTYEEIKNAGPLLGSVLFSKIFGKAVGAQFX 338
R L L+ +S+ + I Y+ N+AY VL +I A + +IFG +
Sbjct: 256 ERNLPLSIGISMPIVTIIYILTNVAYYTVLDMRDIL-ASDAVAVTFADQIFG--IFNWII 312
Query: 339 XXXXXXXXXXXXFVTVYGISRMNQEIFREGLFPFSAQLARNWPCNSPLPSLLICGIVSSF 398
++ SR+ REG P A + +P+PSLL GI++
Sbjct: 313 PLSVALSCFGGLNASIVAASRLFFVGSREGHLP-DAICMIHVERFTPVPSLLFNGIMALI 371
Query: 399 WLYLLPGTGAAFDYLINFEGYGNQIMXXXXXXXXXXXXXXXKRYQFPSRTPIVGVVAFLL 458
+L + LIN+ + P + + + F L
Sbjct: 372 YLCV-----EDIFQLINYYSFSYWFFVGLSIVGQLYLRWKEPDRPRPLKLSVFFPIVFCL 426
Query: 459 LSVYLSVGPFFGNGTGNSVG 478
+++L P + + + +G
Sbjct: 427 CTIFLVAVPLYSDTINSLIG 446
>Hs19923170 [E] KOG1287 Amino acid transporters
Length = 507
Score = 73.9 bits (180), Expect = 6e-13
Identities = 68/315 (21%), Positives = 126/315 (39%), Gaps = 24/315 (7%)
Query: 9 GSKAPLYIIESERDSTEDLSKNVSSLISDNEVPQG--------RHLGIFSTVILFVSRIV 60
G K + + E K +++ +D P G R++ + + V + V I+
Sbjct: 5 GPKRRALAAPAAEEKEEAREKMLAAKSADGSAPAGEGEGVTLQRNITLLNGVAIIVGTII 64
Query: 61 GGGIYSVPSSVFVNCGGNVSLFLFVWLCAAVMAFIGMSMFLELGTILPKSGGRKNFLEFL 120
G GI+ P+ V G + L L VW V + +G + ELGT + KSGG ++ +
Sbjct: 65 GSGIFVTPTGVLKEAG-SPGLALVVWAACGVFSIVGALCYAELGTTISKSGGDYAYMLEV 123
Query: 121 YDKPPMMTTVILCTYCLMTCFAMSPAMILGKYILYALGYGEDFVNKESYASNYIGIAAIM 180
Y P + + + A++ Y+L L + V +E A+ + ++
Sbjct: 124 YGSLPAFLKLWIELLIIRPSSQYIVALVFATYLLKPL-FPTCPVPEE--AAKLVACLCVL 180
Query: 181 VIVFVHGLSLNHGLIIQNXXXXXXXXXXXXMSLAGMYVTLFYHNASYDITQ--PSLLFXX 238
++ V+ S+ +Q+ + L G F D++ P+ F
Sbjct: 181 LLTAVNCYSVKAATRVQDAFAAAKLLALALIILLG-----FVQIGKGDVSNLDPNFSFEG 235
Query: 239 XXXXXXXXXXXXXXXXFIQCFYCFAGWDTVHTVTSEIKDPNRTLKLAGPLSLLMALICYL 298
F + GW+ ++ VT E+ +P R L LA +SL + + Y+
Sbjct: 236 TKLDVGNIVLALYSGLF-----AYGGWNYLNFVTEEMINPYRNLPLAIIISLPIVTLVYV 290
Query: 299 SLNIAYIKVLTYEEI 313
N+AY L+ E++
Sbjct: 291 LTNLAYFTTLSTEQM 305
>HsM4507055 [E] KOG1287 Amino acid transporters
Length = 511
Score = 73.6 bits (179), Expect = 7e-13
Identities = 88/440 (20%), Positives = 163/440 (37%), Gaps = 23/440 (5%)
Query: 39 EVPQGRHLGIFSTVILFVSRIVGGGIYSVPSSVFVNCGGNVSLFLFVWLCAAVMAFIGMS 98
+V + + + + V L V ++G GI+ P V + + L L +W + + G
Sbjct: 30 QVKLKKEISLLNGVCLIVGNMIGSGIFVSPKGVLIY-SASFGLSLVIWAVGGLFSVFGAL 88
Query: 99 MFLELGTILPKSGGRKNFLEFLYDKPPMMTTVILCTYCLMTCFAMSPAMILGKYILYALG 158
+ ELGT + KSG ++ L + + L T L+ S A+I + Y +
Sbjct: 89 CYAELGTTIKKSGA--SYAYILEAFGGFLAFIRLWT-SLLIIEPTSQAIIAITFANYMVQ 145
Query: 159 YGEDFVNKESYASNYIGIAAIMVIVFVHGLSLNHGLIIQNXXXXXXXXXXXXMSLAGMYV 218
AS + A I ++ F++ + G ++Q+ + +AG+
Sbjct: 146 PLFPSCFAPYAASRLLAAACICLLTFINCAYVKWGTLVQDIFTYAKVLALIAVIVAGIV- 204
Query: 219 TLFYHNASYDITQPSLLFXXXXXXXXXXXXXXXXXXFIQCFYCFAGWDTVHTVTSEIKDP 278
+ Q + + ++GWDT++ VT EIK+P
Sbjct: 205 ---------RLGQGASTHFENSFEGSSFAVGDIALALYSALFSYSGWDTLNYVTEEIKNP 255
Query: 279 NRTLKLAGPLSLLMALICYLSLNIAYIKVLTYEEIKNAGPLLGSVLFSKIFGKAVGAQFX 338
R L L+ +S+ + I Y+ N+AY VL +I A + +IFG +
Sbjct: 256 ERNLPLSIGISMPIVTIIYILTNVAYYTVLDMRDIL-ASDAVAVTFADQIFG--IFNWII 312
Query: 339 XXXXXXXXXXXXFVTVYGISRMNQEIFREGLFPFSAQLARNWPCNSPLPSLLICGIVSSF 398
++ SR+ REG P A + +P+PSLL GI++
Sbjct: 313 PLSVALSCFGGLNASIVAASRLFFVGSREGHLP-DAICMIHVERFTPVPSLLFNGIMALI 371
Query: 399 WLYLLPGTGAAFDYLINFEGYGNQIMXXXXXXXXXXXXXXXKRYQFPSRTPIVGVVAFLL 458
+L + LIN+ + P + + + F L
Sbjct: 372 YLCV-----EDIFQLINYYSFSYWFFVGLSIVGQLYLRWKEPDRPRPLKLSVFFPIVFCL 426
Query: 459 LSVYLSVGPFFGNGTGNSVG 478
+++L P + + + +G
Sbjct: 427 CTIFLVAVPLYSDTINSLIG 446
>CE07491 [E] KOG1287 Amino acid transporters
Length = 562
Score = 69.3 bits (168), Expect = 1e-11
Identities = 97/430 (22%), Positives = 174/430 (39%), Gaps = 41/430 (9%)
Query: 49 FSTVILFVSRIVGGGIYSVPSSVFVNCGGNVSLFLFVWLCAAVMAFIGMSMFLELGTILP 108
FS + F + I+G GI+ P + N L L VW+ +++ IG ++ELGT +
Sbjct: 40 FSMYMRFSANIIGAGIFITPGPILQYTFSN-GLALLVWIGCGLISLIGGICYIELGTSIH 98
Query: 109 KSGGRKNFLEFLYDKPPMMTTVILCTYCLMTCFAMSPAM-----ILGKYILYALGYGEDF 163
G +F +Y + + +M+ F S A+ + G ++ L + D
Sbjct: 99 DPGC--DFAYTVYVGWEGIAFSFMWVGVIMS-FPASAAVQALTFVAGMAPIWPLEHPWDG 155
Query: 164 VNKESYASNYIGIAAIMVIVFVHGLSLNHGLIIQNXXXXXXXXXXXXMSLAGMYVTLFYH 223
+ ++ +G A I+V+ ++ +++ +SLA + VT FY
Sbjct: 156 IIEKG-----LGFALIIVLTILNLYAIDK----YASKFQIVVTIAKMLSLAIIIVTGFY- 205
Query: 224 NASYDITQPSLLFXXXXXXXXXXXXXXXXXXFIQCFYCFAGWDTVHTVTSEIKDPNRTLK 283
Y I + + F + FAGWD ++ T EI++P RT+
Sbjct: 206 ---YLIFKGQTEYLEHPFEGSNTNPGQISLAFYGALWSFAGWDILNFGTPEIRNPRRTMP 262
Query: 284 LA--GPLSLLMALICYLSLNIAYIKVLTYEEIKNAGPLLGSVLFSKIFGKAVGAQFXXXX 341
+A G +S++ A+ YL++NI+Y+ VLT +I N+ + + G + F
Sbjct: 263 IALLGGVSIVTAV--YLAMNISYMTVLTPGQIMNSTAVAADFAQITLGGFSYAIPFMIAL 320
Query: 342 XXXXXXXXXFVTVYGISRMNQEIFREGLFPFSAQLARNWPCNSPLPSL---LICGIVSSF 398
++ SR REG P N NSP +L L+C +V +F
Sbjct: 321 LLIGTLNS---NIFCGSRFTHAAAREGHLPTFLSCI-NEESNSPRAALLFQLVCTVVVTF 376
Query: 399 WLYLLPGTGAAFDYLINFEGYGNQIMXXXXXXXXXXXXXXXKRYQFPSRTPIVGVVAFLL 458
T + +Y ++F +G ++ + R P++ F L
Sbjct: 377 -----IDTNSLINY-VSFVMFGQRVFTMTALMWIRYRNIPV--HPDAIRVPLIFSFLFWL 428
Query: 459 LSVYLSVGPF 468
+++ L V PF
Sbjct: 429 ITIALVVVPF 438
>7301546 [E] KOG1287 Amino acid transporters
Length = 517
Score = 68.9 bits (167), Expect = 2e-11
Identities = 64/274 (23%), Positives = 111/274 (40%), Gaps = 21/274 (7%)
Query: 44 RHLGIFSTVILFVSRIVGGGIYSVPSSVFVNCGGNVSLFLFVWLCAAVMAFIGMSMFLEL 103
+ LG+ V + + I G GI+ P V +V L +W+ +++ IG + EL
Sbjct: 57 KQLGLLEGVAIILGIIFGSGIFVSPKGVIREVE-SVGASLVIWVLCGLLSMIGALCYAEL 115
Query: 104 GTILPKSGGRKNFLEFLYDKPPMMTTVILCTYCLMTCFAMSPAMILG----KYILYALGY 159
GT +PKSGG ++ Y P L + M F + I+G Y+L
Sbjct: 116 GTAIPKSGGDYAYIFEAYGSLP----AFLYLWDAMMIFVPTTNAIMGLTFASYVLEPFFG 171
Query: 160 GEDFVNKESYASNYIGIAAIMVIVFVHGLSLNHGLIIQNXXXXXXXXXXXXMSLAGMYVT 219
G + K A + I + +++ + +QN + L G+ V
Sbjct: 172 GACEIPK--IALQLLAAITICFLTYLNSYYMKVTTKMQNVIMFTKIAALVLIILVGL-VW 228
Query: 220 LFYHNASYDITQPSLLFXXXXXXXXXXXXXXXXXXFIQCFYCFAGWDTVHTVTSEIKDPN 279
+ N + T+P F + +AGW+ ++ +T E++DP
Sbjct: 229 MMMGNVE-NFTRP--------FDNTETDPGKMSVAFYSGIFSYAGWNYLNFMTEELRDPY 279
Query: 280 RTLKLAGPLSLLMALICYLSLNIAYIKVLTYEEI 313
R L A +SL + Y+ N+AY+ VL+ E+
Sbjct: 280 RNLPRAIYISLPLVTGIYVLANVAYLAVLSPSEM 313
>CE17028 [E] KOG1287 Amino acid transporters
Length = 521
Score = 61.2 bits (147), Expect = 4e-09
Identities = 60/297 (20%), Positives = 117/297 (39%), Gaps = 36/297 (12%)
Query: 46 LGIFSTVILFVSRIVGGGIYSVPSSVFVNCGGNVSLFLFVWLCAAVMAFIGMSMFLELGT 105
+G+ V I+G GI+ P + V G+V L L +W+ A++ I ++ELGT
Sbjct: 9 IGLIGATSYIVGSIIGSGIFIAPKGI-VEHAGSVGLSLIIWVFCALLNMITAINYIELGT 67
Query: 106 ILPKSGGRKNFLEFLYDKPPMMTTVILCTYCLMTCFAMSPAMILGKYILYAL-------- 157
+P+SG +++++ P + + L + A + GKY++ AL
Sbjct: 68 SIPESGADLAYIDYMGWTPIAFSLLWLSLLIQSSSSAAVLYLTFGKYLVQALEPIVCFTS 127
Query: 158 ----------GYG---EDFVNKESYASNYIGIAAIMVIVFVHGLSLNHGLIIQNXXXXXX 204
G+G + F N++ ++I+F L+L + +
Sbjct: 128 SGADNCAKLFGFGLLCKFFWKLRKPLDNFLIRKPFLIIIFTVFLTLTNMFSLNKFAARVQ 187
Query: 205 XXXXXXMSLAGMYVT------LFYHNASYDITQPSLLFXXXXXXXXXXXXXXXXXXFIQC 258
A + + + + A+ ++ Q
Sbjct: 188 IISMCSKIFATLIIIGIGFFFIIFRGATSHYRSSEIM------KGSDWNAGAIALAIYQG 241
Query: 259 FYCFAGWDTVHTVTSEIKDPN--RTLKLAGPLSLLMALICYLSLNIAYIKVLTYEEI 313
+ F G+ T++ T EI+ N +TL A LL++ + Y+ +N++Y +LT +EI
Sbjct: 242 NWAFGGFTTLNYGTEEIQIENFRKTLPRACLGGLLISAVIYVLVNVSYFAILTPQEI 298
>CE17868 [E] KOG1287 Amino acid transporters
Length = 662
Score = 55.1 bits (131), Expect = 3e-07
Identities = 28/76 (36%), Positives = 45/76 (58%), Gaps = 1/76 (1%)
Query: 36 SDNEVPQGRHLGIFSTVILFVSRIVGGGIYSVPSSVFVNCGGNVSLFLFVWLCAAVMAFI 95
S +E+PQ +G+ + + V IVG GI+ P+S+ +N G+V L L +W A ++
Sbjct: 4 SSSEIPQKHTIGLITAISYTVGDIVGSGIFISPTSI-LNHAGSVGLSLCLWALCACISLF 62
Query: 96 GMSMFLELGTILPKSG 111
G ++ELGT + KSG
Sbjct: 63 GALSYVELGTSIRKSG 78
Database: KOG eukaryal database 04/03
Posted date: Apr 14, 2003 1:07 PM
Number of letters in database: 30,389,216
Number of sequences in database: 60,738
Lambda K H
0.327 0.143 0.442
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 27,831,186
Number of Sequences: 60738
Number of extensions: 1068617
Number of successful extensions: 2825
Number of sequences better than 1.0e-05: 20
Number of HSP's better than 0.0 without gapping: 2
Number of HSP's successfully gapped in prelim test: 18
Number of HSP's that attempted gapping in prelim test: 2776
Number of HSP's gapped (non-prelim): 33
length of query: 535
length of database: 30,389,216
effective HSP length: 111
effective length of query: 424
effective length of database: 23,647,298
effective search space: 10026454352
effective search space used: 10026454352
T: 11
A: 40
X1: 15 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 40 (21.7 bits)