ORF STATUS Function Best COG Functional category Pathways and functional systems
r_klactV0187 good U KOG1809 Intracellular trafficking, secretion, and vesicular transport Vacuolar protein sorting-associated protein
Only best alignment is shown:
BLASTP 2.2.3 [May-13-2002]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= r_klactV0187 68778 59407 -3124
(3124 letters)
Database: KOG eukaryal database 04/03
60,738 sequences; 30,389,216 total letters
Searching..................................................done
Color Key for Alignment Scores: 
Score E
Sequences producing significant alignments: (bits) Value
YLL040c [U] KOG1809 Vacuolar protein sorting-associated protein 2446 0.0
SPBC16C6.02c [U] KOG1809 Vacuolar protein sorting-associated pro... 919 0.0
SPBC21C3.01c [U] KOG1809 Vacuolar protein sorting-associated pro... 391 e-107
SPBC31F10.18c [U] KOG1809 Vacuolar protein sorting-associated pr... 364 1e-99
CE13443 [U] KOG1809 Vacuolar protein sorting-associated protein 315 1e-84
Hs15619010 [U] KOG1809 Vacuolar protein sorting-associated protein 302 7e-81
Hs15619008 [U] KOG1809 Vacuolar protein sorting-associated protein 302 7e-81
Hs20550856 [U] KOG1809 Vacuolar protein sorting-associated protein 280 3e-74
7304192 [U] KOG1809 Vacuolar protein sorting-associated protein 204 2e-51
At1g48090 [U] KOG1809 Vacuolar protein sorting-associated protein 144 3e-33
Hs8923139 [U] KOG1809 Vacuolar protein sorting-associated protein 125 8e-28
Hs22041525 [U] KOG1796 Vacuolar protein sorting-associated protein 100 4e-20
7301869 [U] KOG1809 Vacuolar protein sorting-associated protein 93 8e-18
CE02506 [U] KOG1796 Vacuolar protein sorting-associated protein 86 1e-15
Hs8923545 [U] KOG1809 Vacuolar protein sorting-associated protein 80 5e-14
7294545 [U] KOG1796 Vacuolar protein sorting-associated protein 79 2e-13
ECU04g0690 [U] KOG1809 Vacuolar protein sorting-associated protein 78 3e-13
Hs22048785 [U] KOG1809 Vacuolar protein sorting-associated protein 55 2e-06
CE04771 [U] KOG2993 Cytoplasm to vacuole targeting protein 54 3e-06
CE28285 [S] KOG2955 Uncharacterized conserved protein 53 9e-06
>YLL040c [U] KOG1809 Vacuolar protein sorting-associated protein
Length = 3144
Score = 2446 bits (6339), Expect = 0.0
Identities = 1317/3182 (41%), Positives = 1959/3182 (61%), Gaps = 110/3182 (3%)
Query: 1 MLESLVSALLNRFLGAYVENFDPTQLNVGIWNGDVKLRNLRLRKDSLDALDLPIDVKFGY 60
MLESL + LLNR LG+YVENFDP QLNVGIW+GDVKL+NL+LRKD LD+L+LPIDVK G
Sbjct: 1 MLESLAANLLNRLLGSYVENFDPNQLNVGIWSGDVKLKNLKLRKDCLDSLNLPIDVKSGI 60
Query: 61 LGELTLLIPWSSLKNKPVKIIIEDVYMLCAPRTPESYNVEEQIERELKVKLQRLADFELA 120
LG+L L +PWSSLKNKPVKIIIED Y+LC+PR+ + N EE I+R ++K+++++++EL
Sbjct: 61 LGDLVLTVPWSSLKNKPVKIIIEDCYLLCSPRSEDHENDEEMIKRAFRLKMRKVSEWELT 120
Query: 121 NSS---------KPDINLDSNRNESFTQSLLTKIVDNLQVTVKNIHMRYEDMNSVFSEGP 171
N + K + N F QSL TKI+DNLQVT+KNIH+RYEDM+ +F+ GP
Sbjct: 121 NQARILSTQSENKTSSSSSEKNNAGFMQSLTTKIIDNLQVTIKNIHLRYEDMDGIFTTGP 180
Query: 172 CAFGISLSELSAVSTDESWNPSFISIKQQITHKLATLDSISIYCNTGTESIETDDSEELL 231
+ G++L+ELSAVSTD +W PSFI I Q ITHKL TL+S+ +Y NT + + +DD ++
Sbjct: 181 SSVGLTLNELSAVSTDSNWAPSFIDITQNITHKLLTLNSLCLYWNTDSPPLISDDDQDRS 240
Query: 232 IR-----LRESIAD-NRGAPEYQYLLKPVRGSARLKMNKAGATEDAPHIDVQLMFDEFAL 285
+ ++ IA N AP++QY+LKPV G +L +NK G+TE+ PHID+Q+ +DEF L
Sbjct: 241 LENFVRGFKDMIASKNSTAPKHQYILKPVSGLGKLSINKLGSTEEQPHIDLQMFYDEFGL 300
Query: 286 VLDDCQYKEVLHNLSKYHWFHKTLKYRQHRPTVKPAADPALWFKYAANCVLSEIHEKNYK 345
LDD +Y ++LH LS T K+++ RP+ + +P WFKY A CV++EIHEKN
Sbjct: 301 ELDDTEYNDILHVLSSIQLRQITKKFKKARPSFAVSENPTEWFKYIAACVINEIHEKNKM 360
Query: 346 SSWEYIKERRNKRDEYVSLFKKKLTLPDINDPLPNVEEEKRLHALDVELSFDDIKFFRAF 405
+WE +KE+ +R Y L+ +KL L ++ PL + +E +L L +L++D+I FR+
Sbjct: 361 WTWESMKEKCEQRRLYTKLWVEKLKLKNLEAPLRDPIQEAQLSELHKDLTYDEIILFRSV 420
Query: 406 TRREFCQ-ESKFTQLSET--ISTNANPQ-----------GWFSSWW-APSNAKSDDSLTM 450
+R++ Q + T+ S T S+N PQ W SSWW + D+ L M
Sbjct: 421 AKRQYAQYKLGMTEDSPTPTASSNIEPQTSNKSATKNNGSWLSSWWNGKPTEEVDEDLIM 480
Query: 451 TDEQRKELYDAIEYDDSNDPLKSVDIPKDRTTLRVTNLLQKGSLTVMDRTKGHRMCDFIF 510
T+EQR+ELYDAIE+D++ D + +P++R LRVT+LL+KGS T+ + + + IF
Sbjct: 481 TEEQRQELYDAIEFDENEDKGPVLQVPRERVELRVTSLLKKGSFTIRKKKQNLNLGSIIF 540
Query: 511 EESATEFLNRPDXXXXXXXXXXXXVEDGSPHTLYRHIVSPRT--------------KHEK 556
E +F RPD +EDGSP+ LY+HI+S R + E+
Sbjct: 541 ENCKVDFAQRPDSFLSSFQLNKFSLEDGSPNALYKHIISVRNSSKDQSSIDNHATGEEEE 600
Query: 557 GGDPLLHLYFDSCPMDESADTFLDIKFGSVFVYYHIHFINELIRFFNPPTKHWETVSALM 616
+PLL F+ P+D AD+ L+IK + V+YH+HFI E+ +FF +H ET+ ++
Sbjct: 601 EDEPLLRASFELNPLDGLADSNLNIKLLGMTVFYHVHFITEVHKFFKASNQHMETIGNIV 660
Query: 617 NAAEATVEGWTSQTRMGLEALLNEHKTIDLKLNAASPTIIIPLDAHSWESPCAIIDAGSI 676
NAAEATVEGWT+QTRMG+E+LL +HKT+++ L+ +P II+PLD H W++PCAIIDAG +
Sbjct: 661 NAAEATVEGWTTQTRMGIESLLEDHKTVNVSLDLQAPLIILPLDPHDWDTPCAIIDAGHM 720
Query: 677 KMSSDLVPKQEIKKIKELSVDEYAKIDSDELKRLMFDRFKIKLTDTQLLIGPDMKSSITS 736
+ SDLVPK++IK+IKELS +EY KID +E+ RLMFDRF+I DTQ+ +GPD++S+I
Sbjct: 721 SILSDLVPKEKIKEIKELSPEEYDKIDGNEINRLMFDRFQILSQDTQIFVGPDIQSTIGK 780
Query: 737 INVKQRDNNFTILEKMELDFILDILIFPKALNLPRVAASVTLPSLNIFLNDFQYKIIMQL 796
IN N+F IL+KM+L+ +D+ I PKA LP + LP L++ +ND QYK IM L
Sbjct: 781 INTASSTNDFRILDKMKLELTVDLSILPKAYKLPTIRVFGHLPRLSLSINDIQYKTIMNL 840
Query: 797 VESCVPYVEDDQEEAXXXXXXXXXXQLIPLDNIGGSDEALLKHKETLVLKQTKRMMETLS 856
+ + +P + DD+E N E +K + L LK T + +E +
Sbjct: 841 IANSIPSMIDDEENNGDYV------------NYSSGSEKEMKKQIQLQLKNTLKALENMQ 888
Query: 857 KAELDQTSFQLSLDVSKIEISLLKCLEGPTMNSSKLVKLVGEHLSLRLLKSFVKMDFDLS 916
+++Q +L D+ + +I+ +C++ + NS KLV ++ + L+ K +M+ DL
Sbjct: 889 PLQIEQKFLELHFDIDQAKIAFFQCIKNDSRNSEKLVDILCQRLNFNFDKRAKEMNLDLR 948
Query: 917 LTELRFEDHISKQTSKGCEEYMIFSNGHTK----KEKLFDIRGSRVQQIIEYESNLYEVF 972
+ L ED+I +K E + S+G K ++ LF ++ RVQ+I+ + L E+F
Sbjct: 949 VHSLDVEDYIELTDNK--EFKNLISSGVEKVTRSQKDLFTLKYKRVQRIVPHNDTLIELF 1006
Query: 973 DISVDLRMSELTLSLIPKSILTLMNFVLNTFTDPETPAIPSNVLRQSQQ-QDSTPGNTNV 1031
D + + MSEL L L P+S+LTLMN+ + TFTDP P +P++VLR +++ +D P N+
Sbjct: 1007 DQDIVMHMSELQLVLTPRSVLTLMNYAMLTFTDPNAPEMPADVLRHNKEDRDDAPQKINM 1066
Query: 1032 KIFLDGVNIILNDESSKLATFSIHNSELCMDILPQNXXXXXXXXXXXXVDETSVDLPKDS 1091
KI ++ VN+I ND+S KLAT + E M +LP+ DET+ +DS
Sbjct: 1067 KIKMEAVNVIFNDDSIKLATLVLSAGEFTMVLLPERYNINLKLGGLELTDETNESFSRDS 1126
Query: 1092 VFREIISREDNDLAEVIYETFDPETNTNNYDSYLYYRTGAMRINFIEHSINKIISFFAKF 1151
VFR+II + +L E+ YE+FDP TNT +YDS+L Y TG+M +NFIE ++N++++FFAKF
Sbjct: 1127 VFRKIIQMKGQELVELSYESFDPATNTKDYDSFLKYSTGSMHVNFIESAVNRMVNFFAKF 1186
Query: 1152 QKMKVLFDTAHNNAYSKAPDIDTVNNMKLDIVIRTPSISFPKLIDPRNNVYDELIWNMGD 1211
QK KV FD A AY++AP ID VNNMK+DIVI+ P I FPKL+ + N YD + + +G+
Sbjct: 1187 QKSKVSFDRARLAAYNQAPSIDAVNNMKMDIVIKAPIIQFPKLVGTQENNYDTMRFYLGE 1246
Query: 1212 LYISNTFTG-ELGKLVNNVSAGIKNAHISSIFNFEGRKVQKLSAVSNLDLRFDVSYNQFH 1270
+I N F+ + +N++ G++ +SS NF+G Q+L V N+ L F++ +
Sbjct: 1247 FFIENKFSVIDESHKINHIKLGVREGQLSSNLNFDGSS-QQLYLVENIGLLFNIDRDPLP 1305
Query: 1271 TESDALVTVKGYFAPFYVDLTDLQLQYIYLLSQRIANSFIVSTDDDNME---EVEIAALN 1327
+ + V F F +DLT+ QL Y+ +S +++++F + TD+++ E + EI + +
Sbjct: 1306 QDDTPELKVTSNFESFALDLTENQLTYLLEISNKVSSAFNI-TDENSGESGGKGEIKSPS 1364
Query: 1328 TN-AIIDPQKELHSNQNIFKSEEASSSDNQKNIEIEFEFNAPEFCLSLFNNTSEKITVKD 1386
+ A + + E + + S+ N + ++F F AP+ L+L+N T ++ D
Sbjct: 1365 PDPASLSSESERTATPQSLQGSNKSNIKNPEQKYLDFSFKAPKIALTLYNKTKGVTSLND 1424
Query: 1387 LGIARFTLENFGLSGSAFNTSSANYEMHIKSFTVEDIRYSKTNKHTQLIPKIEGDHHQFM 1446
G+ R ++ G S N + + + H+ +F +ED+R K NKHT+LIPK + +QF+
Sbjct: 1425 CGLTRIMFQDIGCSLGLKNDGTVDGQAHVAAFRIEDVRNIKDNKHTELIPKSKNKEYQFV 1484
Query: 1447 ASVDYKEDKGSSTTTLEVTIDSPKVVLAVEFLLALQSFANSSLNVKQAANFQELSYSKEE 1506
A++ K + + +T+DSPK++LA+++L++L+ F ++ ++ N + ++
Sbjct: 1485 ANISRKNLEVGRLLNISMTMDSPKMILAMDYLVSLKEFFDAIMSKSHENNLYYPENTNQK 1544
Query: 1507 LPNEALPDDLAVASKVENSNKTFNYSVNVVDSAVILLADPSDKQSEAIVFTIGQFLVTDH 1566
N+A+ + + V YSVN++++A+ILLADP D SEAI F IGQFLVTD
Sbjct: 1545 PENKAIVESVQEGGDVTK----IQYSVNIIETALILLADPCDMNSEAISFKIGQFLVTDQ 1600
Query: 1567 NILSIAANNVGLFLSRMGDLNQNRIRILDDFSSTVMIDGRDSTPDILKTQIHSSVGPXXX 1626
NI+++AANNVG+FL +M ++ ++R+LDDFSS++ ID R+STP L T I SV P
Sbjct: 1601 NIMTVAANNVGIFLFKMNS-SEEKLRLLDDFSSSLTIDKRNSTPQTLMTNIQLSVQPLLM 1659
Query: 1627 XXXXXXXXXAMEIFNSSLSLAKDEGLMIVXXXXXXXXXXXXKYGKFSREFKNKIKKYAPS 1686
AM IF +L M K +FS EF+ K+ PS
Sbjct: 1660 RISLRDIRLAMLIFKRVTTLLNK---MTEKEDNGEEEESTDKI-QFSHEFERKLAVLDPS 1715
Query: 1687 MVSSLSEISNVMHRNSISDSTKVITKAEKLHSDFAGLRVVLIGDMHELPIADFNINAFSV 1746
++ S S SI T ++ K E ++D GLR +LIGD+HE+PI D N+N +
Sbjct: 1716 ILGERSRASQSSDSESIEVPTAIL-KNETFNADLGGLRFILIGDVHEMPILDMNVNEITA 1774
Query: 1747 DAKDWSTNIDVISTIEPFASAFNYSRSSWEPLIEVFPMTFHLSK-DDENDNALIFDIITR 1805
AKDWST+ + ++++E + + FNYSRSSWEPL+E+ P+TFHLSK E D A FDI+T+
Sbjct: 1775 SAKDWSTDFEALASLETYVNIFNYSRSSWEPLLEMIPITFHLSKGHSEMDPAFSFDILTQ 1834
Query: 1806 KSVEITLSSRTIALLSQIPASLTKSHNLKPRGAEKPYRIHNDTGHTLNIWIKNSDDDAVN 1865
+ EITLS+R+IA+LS IPASLT+ L R ++KPY++ NDT ++WI+ D +
Sbjct: 1835 RIAEITLSARSIAMLSHIPASLTEELPLASRVSQKPYQLVNDTELDFDVWIQ--DKTTED 1892
Query: 1866 KRANLTKLQSGEIIDWEFEDWRVVRETLDTEKC--MLRASFADDDYSNIIDVDASKEGDV 1923
+ + L++ + WEFEDWR +RE LD +K +L + +Y I+++DA+ EG+
Sbjct: 1893 NKNEVVLLKANTSLPWEFEDWRSIREKLDIDKSKNILGVCVSGQNYKTIMNIDATTEGEN 1952
Query: 1924 IHKLYPPVAGVHNRLLISSNLLENNVKLITFGSTLLLRNLTSTEVE--YGLSDAGKIKSI 1981
+H L PP VHNR++ + ENNVK+ITF STL++ N TSTE+E D K
Sbjct: 1953 LHVLSPPRNNVHNRIVCEARCDENNVKIITFRSTLVIENTTSTEIELLVDSKDPNKPSLK 2012
Query: 1982 GVINPNGTRSIPIDSAYQSSFHIRPLTDNASYKWSGIPIFWKMLSESPLALSCESDLET- 2040
I P+ ++S+P++ AY S IRP +++ Y WS + WK L + +++ C S ++
Sbjct: 2013 YAIKPHQSKSVPVEYAYDSDIRIRPASEDI-YDWSQQTLSWKSLLSNQMSIFCSSKEDSN 2071
Query: 2041 AGFHFEVEGSVDKDDPLSKIYPRMTVTLSAPLVLENSLPQDISFCLKGRKEEARSEIFLQ 2100
FHFE+ D+ +PL+KI+P M + +SA + +EN LP DI+F + ++EE R++ FL+
Sbjct: 2072 QRFHFEIGAKYDEREPLAKIFPHMKIVVSASMTIENLLPADINFSIFDKREEKRTD-FLK 2130
Query: 2101 AGATIPLHNVSLDSYLLLSIKPDDENFNWSNETLVNSPDVSALEEEHRIFITTLDGQKLY 2160
G ++ +H++SLDS+LL+S++P + + S ++VN+P S L E + +T GQ L
Sbjct: 2131 TGESMEVHHISLDSFLLMSVQPLQDEASASKPSIVNTPHKSPLNPEDSLSLTLSGGQNLL 2190
Query: 2161 LSLKY-HANGKRAKTISIYAPYVIMNKTTHDLSVFSDRQWGVVKSDVFMKDGQKLARPKM 2219
L L Y + +G R+K I IY+PY+IMN T +L + S + +S + +++ ++ PKM
Sbjct: 2191 LKLDYKNIDGTRSKVIRIYSPYIIMNSTDRELYIQSS-LLNIAQSKILLENEKRYTIPKM 2249
Query: 2220 FSFQYEDYNRNRAKIKFTETNPSVPVSFDAIGQSVDISLELLNHNQECNLGINVKEGEGK 2279
FSF ED NRA+I+F E+ S +SFDAIGQS D S+ + N QE NLGIN+ EG+GK
Sbjct: 2250 FSFDKEDDKSNRARIRFKESEWSSKLSFDAIGQSFDASVRIKNKEQESNLGINISEGKGK 2309
Query: 2280 YRFTKIVEISPRYIFRNSTSEVIEIMEYGTSSPTILAPKELTPLYFLKRTLSKKFVARFA 2339
Y +K++EI+PRYI N+ IE+ E G+ + PLY ++ + K+ V +F
Sbjct: 2310 YLLSKVIEIAPRYIISNTLDIPIEVCETGSMDVQQIESNITKPLYRMRNIVDKQLVLKFL 2369
Query: 2340 KIPSTWSNPFRLKDVGESFVKMNITDAAQRLIKMDISLEGATVFINAVDSDDNWPFSIRN 2399
S WS PF +K+VG +++K+ + ++ +L+K++I L+ AT+FI D D WPFSIRN
Sbjct: 2370 GGDSNWSQPFFIKNVGVTYLKV-LKNSRHKLLKIEILLDKATIFIRIKDGGDRWPFSIRN 2428
Query: 2400 FSDHEFLFWQRNPRFVXXXXXXXXXXXXXXXXXXXXXPIYYRIPPRSIMPYSWDYPSAKQ 2459
FSDH+F+F+QR+PR V PI+YRIP +SIMPY+WD+P+AK+
Sbjct: 2429 FSDHDFIFYQRDPRKV---SDPYKDDQSNESSSRSFKPIFYRIPSKSIMPYAWDFPTAKE 2485
Query: 2460 KKLYIHTKNRRREIDLNEIGNLRPIRIPSDNPKQPPSIVDINILMDNGVQVLVLSNYNQE 2519
K L + + R RE+ L EIG L P+R+ + +P IV ++++ D+ +Q LV+ NY
Sbjct: 2486 KYLVLESGTRTREVRLAEIGELPPLRLDKRSKDKPAPIVGLHVVADDDMQALVIVNYKAN 2545
Query: 2520 QSLYKLRSQRRFQXXXXXXXXXXXXXDKFEVDESLDSKLNARVVXXXXXXXXXXXNDRLQ 2579
LYKL++ D F V + D K+N ++V N RLQ
Sbjct: 2546 VGLYKLKTAS--ATTTSSVSVNSSVTDGF-VQKDEDEKVNTQIVVSFKGVGISLINGRLQ 2602
Query: 2580 ELCYINILGLEFRFNDSEMYQNLSFKMKWIQIDNQLFGGVYETVLYPTKIPKDSKEIDIH 2639
EL YIN+ G+E R+N+S+ YQ S+KMKW+QIDNQLF G Y +LYPT+IP KEI+ H
Sbjct: 2603 ELLYINMRGIELRYNESKAYQTFSWKMKWMQIDNQLFSGNYSNILYPTEIPYTEKEIENH 2662
Query: 2640 PSLSGAISKVKDESSSLLNFKMATLLLQEMTIQIDEXXXXXXXXXXKIPGASWNQAVDDS 2699
P +SG+ISKV D ++ FK TLL+QE +IQ+DE K PG+ W
Sbjct: 2663 PVISGSISKVNDSLQAVPYFKHVTLLIQEFSIQLDEDMLYAMMDFIKFPGSPWIM----D 2718
Query: 2700 SSEQLFLHPCTVPDFPTTVRSSKVYFEMLHLQPTLLHLSFVRTDRVN--VEEEKSSGNSA 2757
S + + +PD + +YFE+ H+QPT+LHLSF+R+D ++ + EE S+
Sbjct: 2719 SRDYKYDEEIQLPDVSELKTAGDIYFEIFHIQPTVLHLSFIRSDEISPGLAEETEESFSS 2778
Query: 2758 INYFINVLTMALGNIEGAQIKLNSLLLEHVRVSLPTLVGAIESHYAQQFFYQLHKVLGSA 2817
Y++++ M LGNI A +K+NSL +++VRV LP L+ IE HY QF YQ+HK+LGSA
Sbjct: 2779 SLYYVHMFAMTLGNINEAPVKVNSLFMDNVRVPLPILMDHIERHYTTQFVYQIHKILGSA 2838
Query: 2818 DFLGNPVGFFNNISSGVMDIFYEPYQGYIMNDRPQELGIGIAKGGLSFLKKSIFGFSDSF 2877
D GNPVG FN ISSGV D+FYEPYQGY+MNDRPQE+GI +AKGGLSF KK++FG SDS
Sbjct: 2839 DCFGNPVGLFNTISSGVWDLFYEPYQGYMMNDRPQEIGIHLAKGGLSFAKKTVFGLSDSM 2898
Query: 2878 SKMTGSMAKGLSVAIQDTSF-XXXXXXXXXXXGKFGSVGVGASSFFNNVTSGLTGVALDP 2936
SK TGSMAKGLSV QD F ++ A SF + + SGL+G+ALDP
Sbjct: 2899 SKFTGSMAKGLSVT-QDLEFQRVRRLQQRINKNNRNALANSAQSFASTLGSGLSGIALDP 2957
Query: 2937 YSGGAKEXXXXXXXXXXXXXXXLPAKTAIGVLDLASNVSEGIRNSTTLMDIGQIERVRLP 2996
Y KE LP KTAIG LDL SN+S+G++++TT++D+ + RVRLP
Sbjct: 2958 YKAMQKEGAAGFLKGLGKGIVGLPTKTAIGFLDLTSNLSQGVKSTTTVLDMQKGCRVRLP 3017
Query: 2997 RFVSSDKLIKPYNLRDSQGQYWLKTCNGGEYAKDMYVGHVICETPAGYQIVIVSLQRILR 3056
R+V D++IKPY+LR++QGQYWLKT NGG + D Y+ HVI P VIVS+Q I
Sbjct: 3018 RYVDHDQIIKPYDLREAQGQYWLKTVNGGVFMNDEYLSHVI--LPGKELAVIVSMQHIAE 3075
Query: 3057 MQLSTLTVMEHIPFRMIRNVRVIKTGITI-YTAEREYFFSVPKDEERRYLYKLVHTAVIE 3115
+Q++T +M + I+ + + ++G+ I ++ EYF + EERR LY+ + AV E
Sbjct: 3076 VQMATQELMWSTGYPSIQGITLERSGLQIKLKSQSEYFIPISDPEERRSLYRNIAIAVRE 3135
Query: 3116 FN 3117
+N
Sbjct: 3136 YN 3137
>SPBC16C6.02c [U] KOG1809 Vacuolar protein sorting-associated protein
Length = 3131
Score = 919 bits (2375), Expect = 0.0
Identities = 809/3171 (25%), Positives = 1401/3171 (43%), Gaps = 311/3171 (9%)
Query: 1 MLESLVSALLNRFLGAYVENFDPTQLNVGIWNGDVKLRNLRLRKDSLDALDLPIDVKFGY 60
MLE L++ LNR LG Y+ENFD TQL V +WNGDV LRNL+L++ + L+LPI V++G
Sbjct: 1 MLEGLLANFLNRLLGEYIENFDATQLKVAVWNGDVTLRNLQLKRSAFRKLELPISVQYGL 60
Query: 61 LGELTLLIPWSSLKNKPVKIIIEDVYMLCAPRTPESYNVEEQIERELKVKLQRLADFELA 120
+ ELTL IPWSSLKNKPV+I I + L + E + L+ K +++ +E +
Sbjct: 61 VEELTLKIPWSSLKNKPVEIYIVGIRALASMEENVKSQSEVDPHQVLESKRRQMQLWEAS 120
Query: 121 NSSKPDINLDSNRNESFTQSLLTKIVDNLQVTVKNIHMRYEDMN-SVFSEGPCAFGISLS 179
K + D + ++FT+SL+T+++DN+Q+ +++IH+R+E + S G +FG+ LS
Sbjct: 121 QIGKAETAYDP-KTQTFTESLITRMIDNIQINIRDIHIRFEHLPVSNVVPGGYSFGLLLS 179
Query: 180 ELSAVSTDESWNPSFISIKQQITHKLATLDSISIYCNTGTESIETDDSEELLIRLRESIA 239
E S S +E W +F+ + Q +KL +L IY + E I+ D EL+ + I
Sbjct: 180 EFSIESCNEEWTSTFVETESQTIYKLCSLRGFGIYSDETAECIDKTDINELMNTFQALIT 239
Query: 240 DNRGAPEYQYLLKPVRGSARLKMNKAGATEDAPHIDVQLMFDEFALVLDDCQYKEVLHNL 299
D + + E Y++ PV G A++ +NK T + P Q+ F F + L+D Q +
Sbjct: 240 DFQ-SREKDYIIAPVTGMAKVTINKL-PTPEIPRFLSQISFRGFDVSLNDSQISCGMSLA 297
Query: 300 SKYHWFHKTLKYRQHRPTVKPAADPALWFKYAANCVLSEIHEKNYKSSWEYIKERRNKRD 359
+ L +R+ P + ++ L +I +K+Y SW IK KR
Sbjct: 298 HELQDVMSKLAFRKRIVGNVSLDTPLDYLRFIFQKTLHDIQQKHYARSWPAIKAFCEKRR 357
Query: 360 EYVSLFKKKLTLPDINDPLPNVEEEKRLHALDVELSFDDIKFFRAFTRREFCQESKFTQL 419
Y+ L+KKK + + +E K L L++ L +K FR+ +E E Q
Sbjct: 358 NYIKLYKKKFLAVQL-----SADESKELDVLELNLDISQLKLFRSLAYQEIKNEGFEPQ- 411
Query: 420 SETISTNANPQGWFSSWWAPSNAKSDDSLTMTDEQRKELYDAIEYDDSNDPLKSV-DIPK 478
QGW S W SD++ +TD+QRK + DAI +DS V D+
Sbjct: 412 ------PPKQQGWGSWMWNSFRGASDENGEVTDDQRKTVIDAIGLNDSIIESAHVGDLQS 465
Query: 479 DRTTLRVTNLLQKGSLTVMDRTKGHRMCDFIFEESATEF-LNRPDXXXXXXXXXXXXVED 537
+ + V + G +++ K + ++F N+ D D
Sbjct: 466 NTSLFDVRLEVPSGKFSLLKYPKKENVISLELLNFFSQFKCNKKDYSFVANLGSLKMYND 525
Query: 538 GSPHTLYRHIVSPRTKHEK----GGDPLLHLYFDSCPMDESADTFLDIKFGSVFVYYHIH 593
R+ + PR K + L F+ D++ L I ++ +Y +
Sbjct: 526 D------RNFLYPRETSNKEIETTSPSIFTLSFERSSSDDNDTDTLGINLRALEFFYDPN 579
Query: 594 FINELIRFFNPPTKHWETVSALMNAAEATVEGWTSQTRMGLEALLNEHKTIDLKLNAASP 653
+ ++ F + L+ A V +TSQT L+ LNE + +++ +P
Sbjct: 580 LLLR-VKGFQSSLFANDNGRKLVRLANDAVTDFTSQTVQNLQEYLNEKRKLNVNFQFQTP 638
Query: 654 TIIIPLDAHSWESPCAIIDAGSIKMSSDLVPKQEIKKIKELSVDEYAKIDSDELKRLMFD 713
+I P D ++ ES +DAG I ++S V D+ + +S+ L L++D
Sbjct: 639 LLIFPEDCNNPESFSLFVDAGFISITSQNVETN----------DKESNSESETLYHLIYD 688
Query: 714 RFKIKLTDTQLLIGP--DMKSSITSINVKQRDNNFTILEKMELDFILDILIFPKALNLPR 771
R+++ L +LL+GP ++K+ IN + ++ ++ + + P PR
Sbjct: 689 RYRVSLESARLLLGPLNELKNESNKIN-----EEYYLMNELNTEIFIQAQRVPTP-QYPR 742
Query: 772 VAASVTLPSLNIFLNDFQYKIIMQLVESCVP--YVEDDQEEAXXXXXXXXXXQLIPLDNI 829
+ +P L+ L+D Q++I+ L + + DD + D
Sbjct: 743 IKVEGNMPCLSFILSDAQFRILNNLASTMLKDGKASDDDDNG---------------DWR 787
Query: 830 GGSDEALLKHKETLVLKQTKRMMETLSKAELDQTSFQLSLDVSKIEISLLKCLEGPTMNS 889
S E+L H+ L T + S ++ E++L+ C E
Sbjct: 788 PESSESLDSHESEYKLNNTPSEQSV-------KVSHFFEFNMKLGEVTLILCREDSQTKR 840
Query: 890 SKLVKLVGEHLSLRLLKSFVKMDFDLSLTELRFEDHISKQTSKGCEEYM-IFSNGHTKKE 948
+ +V + L L + +S+ D +SK + + M ++ E
Sbjct: 841 NSMVSVNFAKLLLSFNQFEDNSHLRMSINSFHINDMLSKSSRDNNRQLMRCYAPDSVDAE 900
Query: 949 KLFDIRGSRVQQIIEYESNLYEVFDISVDLRMSELTLSLIPKSILTLMNFVLNTFTDPET 1008
I + + E +S + +VD + L SILTL+ F L +F P
Sbjct: 901 NTPVIVEIKSVKAGENQSET----NTTVDFLCANGDFYLAKFSILTLIEF-LPSFAPP-- 953
Query: 1009 PAIPSNVLRQSQQQDSTPG---NTNVKIFLDGVNIILNDESSKLATFSIHNSELCMDILP 1065
PSN + + Q ++ N KI G+ ++ N ES +C+D+L
Sbjct: 954 ---PSNDKQSTPQVSNSAAGKMELNFKIHKIGLRLLENYES----------KPICIDLLA 1000
Query: 1066 QNXXXXXX---XXXXXXVDETSV---DLPKDSVFREIISREDN--DLAEVIYETF----- 1112
+ VD+ V D KD + I S++D+ DL + E +
Sbjct: 1001 LDLSVNSTKGISEVESRVDKIQVMAWDHEKDEIVTLIDSKQDSLFDLKCKMQEGWFIHSP 1060
Query: 1113 DPETNTNNYDSYLYYRTGAMRINFIEHSINKIISFFAKFQKMKVLFDTAHNNAYSKAPDI 1172
+P T+ N + G+ + + I +I+++ + F K + + A + +
Sbjct: 1061 NPSTDVN-------IKMGSFTMLCHKQPIEEILNYASNFGHYKAIVQSVKYLAETGTHQV 1113
Query: 1173 DTVNNMKLDIVIRTPSISFPKLIDPRNNVYDELIWNMGDLYISNTFTGELGKLVNNVSAG 1232
N+ +++ I P P ++ ++ E++ L + ++ L + + S
Sbjct: 1114 QQGTNVNINLYISNPIFQIPLTLENGSSAMVEILPGSFSLK-TPSWLPNLTLNLESKSTT 1172
Query: 1233 IKNAHISSIFNFEGRKVQKLSAVSNLDLRFDVSYNQFHTESDALVTVKGYFAPFYVDLTD 1292
++ + S F+ +G ++ + + +L++ D S Q D+ +T Y + +++
Sbjct: 1173 LRTIYYSKDFDEKGNQI---TVLDDLNISLDGSIVQ---AVDSAIT--NYAIDLHCGISE 1224
Query: 1293 L-----QLQYIYLLSQRIANSFIVSTDDDNMEEVEIAALNTNAIIDPQKELHSNQNIFKS 1347
L Q QY+ LL ++A++ N + A + ++ +EL+S + +
Sbjct: 1225 LLIHLSQAQYLILL--KLASNLPEMLSIANAFSANVDAPSVMTLL--SEELYSIDTV--N 1278
Query: 1348 EEASSSDNQKNIEIEFEFNAPEFCLSLFNNTSEKITVKDLGIARFTLENFGLSGSAFNTS 1407
+ S+ + +++F + P+ L+L++ T ++ FTL GS +
Sbjct: 1279 DAISNLSQNSSFDMKFGLHFPKISLNLYDGTFITPENSLSPLSNFTLNEIRAEGSYDLKT 1338
Query: 1408 SANYEMHIKSFTVEDIRYSKTNKHTQLIPKIEGDHHQFMASVDYKEDKGSSTTTLEVTID 1467
A+ + + S +ED+R K+ + +I Q S YK D +S+ LE I
Sbjct: 1339 GASALIKMASLAIEDVRSEKSRYFSNVIIPSTDTESQLQVSFQYKPD--TSSILLEGDIF 1396
Query: 1468 SPKVVLAVEFLLALQSFANSSLNVKQAANFQELSYSKEELPNEALPDDLAVASKVENSNK 1527
VL+++ LL++ + L K+ S +++ + ++ + S K
Sbjct: 1397 KSMYVLSLDHLLSIYYWFGQPLMEKKLE-------SPDDVQSLQAESSVSTPAVTAASEK 1449
Query: 1528 TFNYSV--NVVDSAVILLADPSDKQSEAIVFTIGQFLVTDHNILSIAANNVGLFLSRMGD 1585
+ + SV ++ +++++ +AD S S+AIV Q + S+ +G+F++RM
Sbjct: 1450 SISLSVRFDIRNTSLVFVADASKSTSQAIVLRTDQISLVKQLSYSLTVQKMGMFVTRMDK 1509
Query: 1586 LNQNRIRILDD----------------FSSTVMIDG---RDSTPDILKTQIHSSVGPXXX 1626
L+ I+ILDD FS+T+ +D R S D+L Q +
Sbjct: 1510 LDDG-IQILDDFDIGFGLVQDCSENKSFSATLDLDRLLFRISVYDLLLLQSIAQASVSVI 1568
Query: 1627 XXXXXXXXXAMEIFNSSLSLAKDEGLMIVXXXXXXXXXXXXKYGKFSREFKNKIKKYAPS 1686
E NS D G I+ + K ++ A +
Sbjct: 1569 SSYKDKSSSISENMNSG-----DYGQQILNASNIAA-------------VQQKAEQTATT 1610
Query: 1687 MVSSLSEISNVMHRNSISDSTKVITKAEKLHSDFAGLRVVLIGDMHELPIADFNINAFSV 1746
+++ L S + +E+ + AG++++LI D H LP+ DF I F+V
Sbjct: 1611 LLTVLGHDSLI---------------SEEFTINSAGIQLILISDAHCLPVFDFTIENFNV 1655
Query: 1747 DAKDWSTNIDVISTIEPFASAFNYSRSSWEPLIEVFPMTFHLSKDDENDNALIFDIITRK 1806
KDWSTN+ +++ +AFN+++S WEP+IE P TF + I+
Sbjct: 1656 LVKDWSTNLSATTSLTLHCNAFNFAKSHWEPVIE--PWTFSTTA-----------IMKDG 1702
Query: 1807 SVEITLSSRTIALLSQIPASLTKSH------------NLKPRGAEKPYRIHNDTGHTLNI 1854
E+ ++S IA +S P +T H N++ R PY I N TG+ L+I
Sbjct: 1703 MHEVNINSDDIAQISLTPMMVTDVHRLIKFYLTNQENNIEKRPEGYPYVILNQTGYNLSI 1762
Query: 1855 WIKNSDDDAVNKRANLTKLQSGEIIDWEFEDWRVVRETLDTE----KCMLRASFADDDYS 1910
N + + L SG+ + FE V+ + ++ +R SF D +
Sbjct: 1763 QYGNLNSSEMQS----LSLPSGKCVPCRFESKEVLTSRMSSKVQDVATKVRVSF-DSTWY 1817
Query: 1911 NIIDVDASKEGDVIHKLYPPVAGVHNRLLISSNLLENNVKLITFGSTLLLRNLTSTEVEY 1970
+ +V +EG +++L P + LL++ LLE+N+K I S + N T +E
Sbjct: 1818 PVDEVSVHQEGSFLYELKPRI-DQRTFLLVTVVLLESNIKQIILSSPYSIVNRTKEVIEV 1876
Query: 1971 GLSDAG--KIKSIGVINPNGTRSIPIDSAYQSSFHIRPLTDNASYKWSGIPIFWKMLSES 2028
+D + S+ I+PN T +P+D A IRP++ + WS + W L++S
Sbjct: 1877 VCNDRSGHRQSSVIKIDPNETGYVPLDLACLYPLRIRPVS-KLGFLWSNQIVDWHSLNKS 1935
Query: 2029 PLA-LSCESDLETAGFHFEVEGSVDKDDPLSKIYPRMTVTLSAPLVLENSLPQDISFCLK 2087
PL L+CES + + V D L YP + + + L +EN LP +I+ +
Sbjct: 1936 PLQYLTCESTSTSWKHNLLVFARNLMDGSLQNDYPFLQLNILPTLQIENLLPYEINLRII 1995
Query: 2088 GRKEEARSEIFLQAGATIPLHNVSLDSYLLLSIKPDDENFNWSNETLVNSPDVSALEEEH 2147
R L G ++P+ + S+LL+ I D + + ++ +P S + +
Sbjct: 1996 ERSSGNDWRSSLSPGDSLPILHTDSKSFLLMGINVPDLDLQPVDLPIIYTPISSGQDVQT 2055
Query: 2148 RIFITTLDGQ---KLYLSLKYHANGKRAKTISIYAPYVIMNKTTHDLSVFSDRQWGV--- 2201
+T D Q KL L + + IY PYVI N T + V S +
Sbjct: 2056 SALLTASDKQDVVKLILKYEKLPGTNYVSKVMIYPPYVIFNHTDLSIQVTSSSPNSIRYT 2115
Query: 2202 VKSDVFMKDGQKLARPKMFSFQYEDYNRNRAKIKFTE-TNPSVPVSFDAIGQSVDISLEL 2260
+ S + D +P +SF E +NRA I T+ S + FD +G S + +
Sbjct: 2116 IPSGSYSND----IKPYFYSFD-ESGRKNRAMISIDNGTSWSADIGFDTLGSSSQVEVRK 2170
Query: 2261 LNHNQECNLGINVKEGEGKYRFTKIVEISPRYIFRNSTSEVIEIMEYGTSSPTILAPKEL 2320
N + C LG+++ E GK+ TK V +PR++F+N + + E+G+S L EL
Sbjct: 2171 TNESDVCLLGMSISESSGKFCLTKSVTFTPRFVFKNHLDCTVSLREFGSSKVLHLPSNEL 2230
Query: 2321 TPLYFLKRTLSKKFVARFAKIPST---WSNPFRLKDVGESFVKM-----NITDAAQRLIK 2372
P+ + + + +A +PS+ W++PF ++VG +K + + + L++
Sbjct: 2231 IPMMYFS---NPQEIALLLSLPSSNNHWTSPFLAQNVGIVHLKAFEFDDDDNNMSTTLLR 2287
Query: 2373 MDISLEGATVFINAVDSDDNWPFSIRNFSDHEFLFWQRNPRFVXXXXXXXXXXXXXXXXX 2432
+ ++LE AT F+ D WPF ++N + E + Q+ P
Sbjct: 2288 LCVTLEDATFFVTITKEDKAWPFRLKNCTSREICYEQKRP----------DPESVDSRFL 2337
Query: 2433 XXXXPIYYRIPPRSIMPYSWDYPSAKQKKLYIHTKNRRREIDLNEIGNLRPIRIPSDNPK 2492
+ Y + P YSWD+P K K L + ++D++ +G L P
Sbjct: 2338 QGSRSMKYALNPGEEANYSWDFPILKSKLLQVEVGKAIHDLDISSVGQLEPWH------- 2390
Query: 2493 QPPSIVDINILMDNGVQVLVLSNYNQEQSLYKLRSQRRFQXXXXXXXXXXXXXDKFEVDE 2552
P+ +D I + V+V SL L + K + E
Sbjct: 2391 --PTELDQKIRIHPEVKV---------DSLTSLVTFNEIDLSKPKLPSRTNSNVKGSIVE 2439
Query: 2553 SLDSKLNARVVXXXXXXXXXXXNDRLQELCYINILGLEFRFNDSEMYQNLSFKMKWIQID 2612
++V + + +E Y + FRF+DS+ + W+QID
Sbjct: 2440 Q-----KFKLVLQLKGFGISLIDKKYEEFAYATLKNFTFRFDDSKDLNTFGMSLGWLQID 2494
Query: 2613 NQLFGGVYETVLYPTKIPKDSKEIDIHPSLSGAISKVKDESSSLLNFKMATLLLQEMTIQ 2672
NQ+ VY L+PT I ++ K+ D L S +KD S ++L K A+LLLQE++++
Sbjct: 2495 NQMLDSVYPIALFPTMITQEVKQ-DDPQLLQLRFSVLKDSSFNILYIKYASLLLQELSLE 2553
Query: 2673 IDEXXXXXXXXXXKIPGASWNQAVDDSS-SEQLFLHPCTVPDFPTTVRSSKVYFEMLHLQ 2731
+++ ++ S + + D +S S+ F +PD V S V+FE LHLQ
Sbjct: 2554 VED---RLVLTLLQLLYPSSDVSKDSASLSKNAFADKFEIPDLDADVYRSNVFFETLHLQ 2610
Query: 2732 PTLLHLSFVRTDRVNVEEEKSSGNSAINYFINVLTMALGNIEGAQIKLNSLLLEHVRVSL 2791
PT L++SF T + + S N +++ +L LGNI A ++LNS+LLE+ R +L
Sbjct: 2611 PTRLNISF-ETSYESDQPAVKSSNPTLDFMTGILISTLGNIHDAPVQLNSILLENARGTL 2669
Query: 2792 PTLVGAIESHYAQQFFYQLHKVLGSADFLGNPVGFFNNISSGVMDIFYEPYQGYIMNDRP 2851
+ + SHY QQ YQ++K+ G ADFLGNPVG FNN++SGV D+FYEPYQG+++ D
Sbjct: 2670 SEMANRVASHYKQQVGYQIYKIAGRADFLGNPVGLFNNVASGVFDMFYEPYQGFLLQD-S 2728
Query: 2852 QELGIGIAKGGLSFLKKSIFGFSDSFSKMTGSMAKGLSVAIQDTSFXXXXXXXXX----X 2907
Q G A+G SF++K+I+G SDS SK+TG+++KGLS D +
Sbjct: 2729 QSFGDSFARGTSSFMRKTIYGVSDSVSKITGTISKGLSTMTMDPKYQNSRRRFRSRNRPK 2788
Query: 2908 XGKFGSVGVGASSFFNNVTSGLTGVALDPYSGGAKEXXXXXXXXXXXXXXXLPAKTAIGV 2967
+G V GA+SF+++++SG G+ P++ L K AIG+
Sbjct: 2789 EAVYG-VTAGANSFYDSMSSGFKGLK-KPFTDPKNNSAGKFLKGFGKGMLGLATKPAIGL 2846
Query: 2968 LDLASNVSEGIRNSTTLMDIGQIERVRLPRFVSSDKLIKPYNLRDSQGQYWLKTCNGGEY 3027
LD+ SNVSEGIRNST + +I++VR+PR+V LI P+ +S G+Y L + G+Y
Sbjct: 2847 LDMTSNVSEGIRNSTDVRTNPEIDKVRVPRYVEFGGLIVPFKPYESLGKYMLSCLDDGKY 2906
Query: 3028 AKDMYVGHVICETPAGYQIVIVSLQRILRMQLSTLTVMEHIPFRMIRNVRV 3078
A D Y+ H + I+ +S + + + S V +P + I +RV
Sbjct: 2907 AFDEYLYHAEIQ---NVDILYISTKHFI-ITGSNYIVKIAVPVKQISGLRV 2953
>SPBC21C3.01c [U] KOG1809 Vacuolar protein sorting-associated protein
Length = 2503
Score = 391 bits (1004), Expect = e-107
Identities = 399/1652 (24%), Positives = 696/1652 (41%), Gaps = 166/1652 (10%)
Query: 1 MLESLVSALLNRFLGAYVENFDPTQLNVGIWNGDVKLRNLRLRKDSLDALDLPIDVKFGY 60
MLE LV+ LLN+ LG+YV+N D QLN+G+W G V L NLR++ ++LD L +PI++ G
Sbjct: 1 MLEGLVAGLLNKILGSYVDNLDTKQLNIGVWGGHVSLHNLRIKPEALDKLGIPIEITSGL 60
Query: 61 LGELTLLIPWSSLKNKPVKIIIEDVYMLCAPRTPESYNVEEQIERELKVKLQRLADFEL- 119
+G TL IPWS+L+NK + I IED+Y+ P+ S +E + + +K ++L FE+
Sbjct: 61 IGTFTLEIPWSNLRNKSLTINIEDIYLSIHPQAKNSLTRDELEQSQQALKQEQLDSFEIL 120
Query: 120 ---------ANSSKPDINLDSNRNESFTQSLLTKIVDNLQVTVKNIHMRYEDMNSVFSEG 170
+SS P+I +R +SF + L+ K+ DN+Q+ ++ IH+R+ED N E
Sbjct: 121 RKNFRETLEESSSNPNI----SRKQSFIEYLIAKLTDNIQIYIERIHLRFED-NLSDLEK 175
Query: 171 PCAFGISLSELSAVSTDESWNPSFIS---IKQQITHKLATLDSISIYCNTGTESIETDDS 227
P + G++L L STD S+ +S I HK+ T+D SIY + E + +
Sbjct: 176 PYSLGLTLYSLRVTSTDASFTEYLLSTDPIPSSCIHKIITVDYFSIYWISKCEISKCTTT 235
Query: 228 EELLIRLRESIADNRGAPEYQYLLKPVRGSARLKMNKAGATEDAPHIDVQLMFDEFALVL 287
E++ L+ I +P Y Y+LKP+R +A + + + T+ + +L +E ++ L
Sbjct: 236 EDIFSYLKNLIPSAEKSPAYNYILKPLRATAHVVLFR-HPTDQIMQLRGKLSVEEISITL 294
Query: 288 DDCQYKEVLHNLSKYHWFHKTLKYRQHRPTVKPAADPALWFKYAANCVLSEIHEKNYKSS 347
D Y +L + + K Y Q+RP P P WFKYA V +HE Y +
Sbjct: 295 SDHMYYSLLGVIDYFRVVMKQQYYLQYRPKSTPKEKPLEWFKYAILVVKDSVHESRYHWT 354
Query: 348 WEYIKERRNKRDEYVSLFKKKLTLPDINDPLPNVEEEKRLHALDVELSFDDIKFFRAFTR 407
W+Y K RR+ R Y+ + +K+ +N+ + E + + ++D IK +R+
Sbjct: 355 WKYFKRRRDDRIAYMHIIRKRY----LNEQISKEEIDLQKKIEKRNSTYDLIK-YRSRVH 409
Query: 408 REFCQESKFTQLSETISTNANPQGWFSSWWAPSNAKSDDSLT--------MTDEQRKELY 459
+E L S WFS + ++ +D+L +TD+++KE +
Sbjct: 410 TSLIEERNSIYLKPKTSAAHGLYDWFSGYIRKPQSQDEDTLASTDKTAADLTDQEQKEFF 469
Query: 460 DAIEYDDSNDPLKSVDIPKDRTTLRVTNLLQKGSLTVMDRTKGHRMCDFI---FEESATE 516
AIE+ P +V++ D V + KGS + G R+ I FE ATE
Sbjct: 470 SAIEWSGQLYP-DTVNLDPDMCMANVEVSIAKGSFVIQSHING-RVIPLIKQRFESFATE 527
Query: 517 FLNRPDXXXXXXXXXXXXVEDG--SPHTLYRHIVSPRTKHEKGGD----------PLLHL 564
RP + DG +P ++ + E+ L L
Sbjct: 528 CFIRPQSLKLKVSLKDLDMFDGITNPELEPARVIFAKPSVEESESLQKIPEAYRTHLFFL 587
Query: 565 YFDSCPMDESADTFLDIKFGSVFVYYHIHFINELIRFFNPPTKHWETVSALMNAAEATVE 624
D+ P+ +++ T + + ++ + Y+ I L+ FF PP E VS +A A V
Sbjct: 588 LLDTKPVYKASSTLI-VHLRTLVIIYNRVCIESLLAFFVPPRTKIEHVSEWGYSAAAKVM 646
Query: 625 GWTSQTRMGLEALLNEHKTIDLKLNAASPTIIIPLDAHSWESPCAIIDAGSIKMSSDLVP 684
QTR L+ L HKT D+ ++ +P I++ + +SP +D G + + LV
Sbjct: 647 TLARQTRASLDYALEMHKTSDMTIDLQAPLIVVREECTDLKSPTLFLDVGRALVHTQLVD 706
Query: 685 KQEIKKIKELSVDEYAKIDSDELKRLMFDRFKIKLTDTQLLIGPDMKSSITSINVKQRDN 744
I K ++L + +L+ LM+D+F I L + + LIGPD + T +
Sbjct: 707 DAIIDKFRKLQSKKINNEQLKQLENLMYDKFTISLFNVRCLIGPDYE---TGWRCLPKGC 763
Query: 745 NFTILEKMELDFILDILIFPKALNLPRVAASVTLPSLNIFLNDFQYKIIMQLVESCVPYV 804
++ IL++ LD +I I KA NL + S + I +D QYK+ + ++ + +P +
Sbjct: 764 DYHILKECSLDINFEISILQKATNLTKFKVSSHMKHAEIMFSDVQYKVFINMMSNILPTL 823
Query: 805 EDDQEEAXXXXXXXXXXQLIPLDNIGGSDEALLKHKETLVLKQTKRMMETLSKAELDQTS 864
+ + P D + H E + + Q
Sbjct: 824 PVAE---IPFTYQQFLDAVKPPPFFDAPDNFQITHTSL-----GSHANENTAAQFMAQQI 875
Query: 865 FQLSLDVSKIEISLLKCLEGPTMNSSKLVKLVGEHLSLRLLKSFVKMDFDLSLTELRFED 924
F V SL + + + L+ +V + V FD +T + D
Sbjct: 876 FAFYFKVDYAICSLYR------RSENYLIPVVRAFTEFYI--DLVVRKFDYLVTS-KLND 926
Query: 925 HISKQ---TSKGCEEYMIFSNGHTKKEKLFDIRGSRVQQIIEYES----NLYEVFDISVD 977
+ K+ S C+ ++ S+ K FD I+Y+S ++YE ++
Sbjct: 927 LVIKEFTYPSSLCDNVLVRSSPSPKNN--FDDTVFISYTSIDYDSPELDSVYEGVRTTIA 984
Query: 978 LRMSELTLSLIPKSILTLMNFVLNTFTDPETPAI----PSNVLRQSQQQDSTPGNTNVKI 1033
+ +S+L L++ P + +F+ TFT + P + S + P + NV+
Sbjct: 985 VVLSDLILNVEPTGFSFVYDFIRATFTSLNDEYMIGEDPELTRKISPVEGIIPEDANVR- 1043
Query: 1034 FLDGVNIILNDESSKLATFSIHNSELCMDILPQNXXXXXXXXXXXXVDETSVDLPKDSVF 1093
D V+I L D +T ++++ + M+ + S + PK
Sbjct: 1044 -FDNVDIFLYDCDQHFSTVCLYSANMHMEFREKFFLQARFYDLEVKNHMKSNNPPK---- 1098
Query: 1094 REIISREDNDLAEVIYETFD--PETNTNNYDSYLYYRTGAMRINFIEHSINKIISFFAKF 1151
I+ +DNDL YE++D + + D G++ F + N I F K
Sbjct: 1099 -TIVKIDDNDLFIFKYESYDIPKDISKPTCDCVYDISFGSLTFYFQKSYFNAIYDFLLKL 1157
Query: 1152 QKMKVLFDTAHNNAYSKA-PDIDTVNNMKLDIVIRTPSISFPKLIDPRNNVYDELIWNMG 1210
++ + LF + Y K + ++ K ++ I+ P + F ++D N +LI
Sbjct: 1158 KRFQELFSSIRYAIYYKLYGNKVSLTYPKFELRIKHPKVYFDDVLDEERNCRMQLIVKPQ 1217
Query: 1211 DLYISNTFTGELGKLVNNVSAGIKNAHISSIFNFEGRKVQKLSAVS-------------- 1256
Y + KN+ SIF+ E KV+ +AV
Sbjct: 1218 SFY-----------AFSKCPIVEKNSK-KSIFSCEITKVEFHTAVPSSSHHDVLMEENNV 1265
Query: 1257 NLDLRFDVSYNQ----FHTESDALVTVKGYFAPFYV---DLTDLQLQYIYLLSQRIANSF 1309
+LDL +D +Y F D + +V DL D+ + R+ +SF
Sbjct: 1266 HLDLTYDANYTTGAYVFKATGDLDPVILNMCQSHHVIFWDLIDVATTF-----ARVDSSF 1320
Query: 1310 IVSTDDDNMEEVEIAALNTNAIIDPQKELHSNQNIFKSEEASSSDNQKNIEIEFEFNAPE 1369
S +N+ A + + K H + + ++ ++I FN PE
Sbjct: 1321 YTS---ENLRRELDKAFDRSGTAAKLK--HPKKTVVET-----------LDILTTFNLPE 1364
Query: 1370 FCLSLFNNTSEKITVKDLGIARFTLENFGLS-GSAFNTSSANYEMHIKSFTVEDIRYSKT 1428
L++ + I DL L FG S F +S Y F+++ I+
Sbjct: 1365 IRLNV-HTDDFWIHGGDLTQLHSILSFFGFSLDYNFYSSGRCY----AEFSIDSIQLKDC 1419
Query: 1429 NKHTQLI--PKIE-GDHHQFMASVDYKEDKGSSTTTLEVTIDSPKVVLAVEFLLALQSFA 1485
N ++ +E ++H + + + D + L + IDSPK+ + + +L ++ S
Sbjct: 1420 NPQDNVVFLDVLEYSENHNRLVNGCLEYDSQNPRYNLVLDIDSPKIFVNLNYLYSIWSI- 1478
Query: 1486 NSSLNVKQAANFQELSYSKE-ELPNEALPDDLAVASKVENSNKTFNYSVNVVDSAVILLA 1544
A + L Y E E P+ A + + Y + VD ++
Sbjct: 1479 ---FVHWHRAYYSHLDYLTEVEYFIMGNPNQNACGEE-----SYWYYRITFVDMTLLFFR 1530
Query: 1545 DPSDKQSEAIVFTIGQFLVTDHNILSIAANNV 1576
+ SD ++ G+ L+T +I ++ ANN+
Sbjct: 1531 NVSDANLYSLPMFFGELLITQQSIFAVTANNM 1562
Score = 309 bits (791), Expect = 5e-83
Identities = 223/819 (27%), Positives = 413/819 (50%), Gaps = 45/819 (5%)
Query: 1722 GLRVVLIGDMHELPIADFNINAFSVDAKDWSTNIDVISTIEPFASAFNYSRSSWEPLIEV 1781
G+R+++I +H+LP+ + NI F VD DWS+ ++ + +E F + +N+S S WEP +E
Sbjct: 1690 GIRLLVISQLHDLPLLNINIKPFQVDLNDWSSELNSNAHLELFMNFYNFSNSHWEPFLEP 1749
Query: 1782 FPMTFHLSKDDENDNALIFDIITRKSVEITLSSRTIALLSQIPASLTKSHNLKPRGAEKP 1841
+ + H+S+ + N + + +R+ +++ ++ + I L + + + P
Sbjct: 1750 WKVGVHISR-NPNTSKTAVHVFSREKLDLVITPQLIETLHFGFTKVISTPFPIEFKCDAP 1808
Query: 1842 YRIHNDTGHTLNIW--IKNSDDDAVNKRANLTKLQSGEIIDWEFEDWRVVRETL--DTEK 1897
YRIHN TGH +++W +N+ D V L++ E DW+FE+WR +++ + D ++
Sbjct: 1809 YRIHNYTGHAVSVWADFENAADSCVR------HLENNEETDWKFEEWRQMQDVVKQDQDR 1862
Query: 1898 CMLRASFADDDYSNIIDVDASKEGDVIHKLYP-PVAGVHNRLLISSNLLENNVKLITFGS 1956
+ F + + ++ V ++ G+ I+ L + + +++ NL E+ +K IT S
Sbjct: 1863 SYIGFHFENSKWESLRHVRVNRVGEHIYPLISYDQDELKHYMVVDVNLGEDYIKHITLRS 1922
Query: 1957 TLLLRNLTSTEVEYGLSDAGKIK--SIGVINPNGTRSIPIDSAYQSSFHIRPLTDNASYK 2014
LLL N T E++ D+ I+ I ++P + S+PI++AY S HIRP+++ +
Sbjct: 1923 PLLLINETQMEIDVVFCDSDGIQRSQIYHMSPEESCSLPIETAYYYSIHIRPVSE-FKFN 1981
Query: 2015 WSGIPIFWKMLSESPLAL-SC---ESDLETAGFHFEVEGSVDKDDPLSKIYPRMTVTLSA 2070
W+ I WK L ++ +L +C ++ T F + K +S YP M +T+SA
Sbjct: 1982 WTSEAISWKDLVDNKQSLVTCQHSDNTFSTPACRFAANAEL-KSQTISNHYPFMHITISA 2040
Query: 2071 PLVLENSLPQDISFCLKGRKEEARSEIFLQAGATIPLHNVSLDSYLLLSIKPDDENFNWS 2130
L ++N LP D++ + + +E + G +H++++ LLL + + ++ S
Sbjct: 2041 LLEVKNLLPIDLNIRIIDKDQEGVWMSNVGIGECAYVHSINISHVLLLQAESSESHYLPS 2100
Query: 2131 NETLVNSPDVSALEEEHRIFITTLDGQKLYLSLKYHANGKRAKTISIYAPYVIMNKTTHD 2190
+ + + D SA E + + IT G+K L L Y I I++PY+I+NK+
Sbjct: 2101 SLATIITND-SAQERDEYMTITLQGGRKTRLGLSYTEKYPGIYHIEIFSPYIIINKSGSF 2159
Query: 2191 LSVFSDRQWGVVK-SDVFMKDGQK-LARPKMFSFQYEDYNRNRAKIKFTETNPSVPVSFD 2248
L V + + S + G+ P MFS+ + +Y R +++ +N S PVSFD
Sbjct: 2160 LFVGPKNDYNRISFSSASLSSGEDGKVVPCMFSYSH-NYGSRRCRLRADNSNWSEPVSFD 2218
Query: 2249 AIGQSVDISL-ELLNHNQECNLGINVKEGEGKYRFTKIVEISPRYIFRNSTSEVIEIMEY 2307
AIG ++ L +HN+ LGI V+ G Y T IV I+ R+I RN T + I E
Sbjct: 2219 AIGSVFEVELPSKEDHNKVYRLGIFVETGPDGYSKTNIVTITSRFIVRNKTRWSLVIAEP 2278
Query: 2308 GTSSPTILAPKELTPLYFLKRTLSKKFVARFAKIPSTWSNPFRLKDVGESFVKMNITDAA 2367
+AP+ L +L++ S + + WS+ F ++++G + V++ +T
Sbjct: 2279 YNDFIAEIAPEGEEFLTYLRKH-SHPMLKLSSSDCYLWSSSFYIEEIGSTHVRL-MTSEG 2336
Query: 2368 QRLIKMDISLEGATVFINAVDSDDNWPFSIRNFSDHEFLFWQRNPRFVXXXXXXXXXXXX 2427
++L++++I ++ AT+FI+ + +WP+ I+N S FWQ NP
Sbjct: 2337 EKLLRLEIVIKNATIFISIFEETGDWPYYIKNESGVLLKFWQVNP------------IDA 2384
Query: 2428 XXXXXXXXXPIYYRIPPRSIMPYSWDYPSAKQKKLYIHTKNRRREIDLNEIGNLRPIRI- 2486
Y+ IPP S + YSWDYP K++ + +++ L EIG L P +
Sbjct: 2385 SEGKNNTALLKYHDIPPHSEVKYSWDYPCCANKEIALCYGDQKCLTTLAEIGPLSPFKFT 2444
Query: 2487 -PSDNPKQPPSIVDINILMDNGVQVLVLSNYNQEQSLYK 2524
S+N K + +I+ + ++L+L +Y+ +++ K
Sbjct: 2445 DASNNTK----FISRDIVANGLSKILILKDYDPSKAVRK 2479
>SPBC31F10.18c [U] KOG1809 Vacuolar protein sorting-associated protein
Length = 600
Score = 364 bits (935), Expect = 1e-99
Identities = 210/578 (36%), Positives = 319/578 (54%), Gaps = 21/578 (3%)
Query: 2552 ESLDSKLNARVVXXXXXXXXXXXNDRLQELCYINILGLEFRFNDSEMYQNLSFKMKWIQI 2611
E DS ++ V QEL Y+ G+ F DS + + ++WIQI
Sbjct: 25 EQFDSGIDLSVKFLLEGIGISLVERNTQELAYLTFHGINLFFTDSHLIRTFKLDVRWIQI 84
Query: 2612 DNQLFGGVYETVLYPTKIPKDSKEID--IHPSLSGAISKVKDESSSLLNFKMATLLLQEM 2669
DNQL+GG+Y +LYP+ + ++ D + P+ ++ VK+++ + K AT+LLQE+
Sbjct: 85 DNQLYGGIYPIILYPSILSQEDTMNDNSLLPTFHSMVAVVKNDTYGVTYVKYATILLQEL 144
Query: 2670 TIQIDEXXXXXXXXXXK--IPGASWNQAVDDSSSEQLFLHPCTVPDFPTTVRSSKVYFEM 2727
TI+IDE K +P + N S +L VP+ KVYFE+
Sbjct: 145 TIEIDEDFAFAALEYIKDSVPRSKRNTGKMFDDSLEL------VPE--NLGNDLKVYFEV 196
Query: 2728 LHLQPTLLHLSFVRTDRVN-VEEEKSSGNSAINYFINVLTMALGNIEGAQIKLNSLLLEH 2786
L+LQPT +HLSFVRT+R+N + S ++ +F+NVL+MA+GNI A ++LN+LL+++
Sbjct: 197 LNLQPTEMHLSFVRTERINNTDGTVVSSHNPFVFFVNVLSMAIGNINDAPVRLNALLMDN 256
Query: 2787 VRVSLPTLVGAIESHYAQQFFYQLHKVLGSADFLGNPVGFFNNISSGVMDIFYEPYQGYI 2846
VSL L +++HY+Q+ Q+HK++GSADFLGNPVG F I+SG DIFYEP+ G+I
Sbjct: 257 AHVSLRRLFELVKNHYSQELLSQVHKIVGSADFLGNPVGLFTTITSGFADIFYEPFHGFI 316
Query: 2847 MNDRPQELGIGIAKGGLSFLKKSIFGFSDSFSKMTGSMAKGLSVAIQDTSFXXXXXXXXX 2906
+N+ ELGIG AKG SF+KK++FG +DS SK+TG++++ LSV D F
Sbjct: 317 LNEGSYELGIGFAKGTASFIKKAVFGITDSISKVTGTISRSLSVITLDPKFQSRRRAARI 376
Query: 2907 XXGK---FGSVGVGASSFFNNVTSGLTGVALDPYSGGAKEXXXXXXXXXXXXXXXLPAKT 2963
V GA+S + V SG+ G+AL P G + K
Sbjct: 377 RNRPVHILYGVTAGAASLYTGVRSGVRGLALQPIIGARRNGLPGLVKGLGKGLVGFTTKP 436
Query: 2964 AIGVLDLASNVSEGIRNSTTLMDIGQIERVRLPRFVSSDKLIKPYNLRDSQGQYWLKTCN 3023
+G+ D AS++SEG RN+TT+ D IE++RL R +S D ++ P+ LR++ GQYWLK +
Sbjct: 437 LVGLFDFASSISEGARNTTTVFDERHIEKLRLSRLMSDDGVVYPFQLREALGQYWLKHLD 496
Query: 3024 GGEYAKDMYVGHVICETPAGYQIVIVSLQRILRMQLSTLTVMEHIPFRMIRNVRV-IKTG 3082
G Y KD Y H+I E +VI++ RIL +Q L + I ++ V++ K
Sbjct: 497 NGRYFKDFYKAHIIIENKV---LVILTNNRILFVQPQQLNCKKEIHLSKVKTVKLQSKEH 553
Query: 3083 ITIYTAEREYF-FSVPKDEERRYLYKLVHTAVIEFNSK 3119
I + + F FSVP++ R + Y+ + + + K
Sbjct: 554 IFLQLLKGVNFEFSVPENSVRTFFYRKIRDELAAYKHK 591
>CE13443 [U] KOG1809 Vacuolar protein sorting-associated protein
Length = 3212
Score = 315 bits (806), Expect = 1e-84
Identities = 516/2560 (20%), Positives = 1025/2560 (39%), Gaps = 332/2560 (12%)
Query: 1 MLESLVSALLNRFLGAYVENFDPTQLNVGIWNGDVKLRNLRLRKDSLDALDLPIDVKFGY 60
+ ESLV+ LLNRFLG +V+N D +QLN+GIW GDVKL NL++++ +LD DLPI +K+GY
Sbjct: 2 VFESLVADLLNRFLGDFVDNLDSSQLNIGIWGGDVKLDNLQVKETALDDFDLPIKLKYGY 61
Query: 61 LGELTLLIPWSSLKNKPVKIIIEDVYMLCAPRTPESYNVEEQIERELKVKLQRLADFELA 120
L L L IPW +L N+PV ++ + ++ P YN E+ + ++K + LA E A
Sbjct: 62 LSSLVLKIPWKNLYNEPVIATVDGLNLIVVPNKGVVYNEEKVAKNIQEIKQKTLARLEEA 121
Query: 121 NSSKPDINLDSNRNESFTQSLLTKIVDNLQVTVKNIHMRYEDMNSVFSEGPCAFGISLSE 180
+ + ++FT+ ++T+I+ NLQ++V NIH+R+ED P A GI+L +
Sbjct: 122 RKERR--KPKDPQADTFTEKMITQIIKNLQISVSNIHVRFED-RYTNRHRPFAMGITLEK 178
Query: 181 LSAVSTDESWNPSFISIKQQITHKLATLDSISIYCNTGTESI-ETDDSEELLIRLRESIA 239
L+ +TDE+W + +I +KL +L +++IY N+ TE I + DD E + +L+E+I
Sbjct: 179 LNFKTTDENWRETIHKDVVKIIYKLVSLQNLAIYWNSSTEFISDLDDKEAIRKKLQETIH 238
Query: 240 DNRGAPE-YQYLLKPVRGSARLKMNKAGATEDA----PHIDVQLMFDEFALVLDDCQYKE 294
+ + PE Y Y+L+P++ A+LK+N+ T+ + P ID+ + ++ + QY++
Sbjct: 239 NGKNGPEGYNYILEPIQMEAKLKLNQKPETDGSNWKIPKIDLAVDMHALSIAIGKFQYQD 298
Query: 295 VLHNLSKYHWFHKTLKYRQHRPTVKP-AADPALWFKYAANCVLSE-IHEKNYKSSWEYIK 352
VL L F+ +Y ++RP + W+K+A +L E + + SW+ ++
Sbjct: 299 VLLFLEAQERFNAAGQYLKYRPNLNEFKGHYKAWWKFAYTSILEEKVRRRRNNWSWDRMQ 358
Query: 353 ERRNKRDEYVSLFKKKLTLPDINDPLPNVEEEKRLHALDVELSFDDIKFFRAFTRREFCQ 412
+ R +Y + ++ T + P + + + + +L ++ R E +
Sbjct: 359 KHRQLVRKYQKAWVRRQT-----EASPGADVQATIKEAEKKLDVFNVNVARQQAELEIDR 413
Query: 413 ESKFTQLSETISTNANPQGWFSSWWAPSNAK--------SDDSLTMTDEQRKELYDAIEY 464
E Q + A + WF P+ K S MT E++ +L++AI+Y
Sbjct: 414 EGLTRQEDKPTGWVAWGKSWFGGGGGPTPDKKKGAKDIGSQFQEAMTPEEKAKLFEAIDY 473
Query: 465 DDSNDPLKSVDIPKDRTTLRVTNLLQKGSLTVMDRTKGHRMCDFIFEESATEFLNRPDXX 524
++ P + PK+ + L + ++ V+D ++ + RP
Sbjct: 474 QENIPP---TNYPKEFVENKFDFKLGQVAI-VVDGAVSMQLLKLV-----ASVEQRPSAS 524
Query: 525 XXXXXXXXXXVEDGSPHTLYRHIVSPRTKHEKGGDPLLHLYFDSCPMDESADTFLDIKFG 584
+ T + P P + D+ P+ + D + +
Sbjct: 525 AMHVESSIQELRMDGCGTEIIRVRDPSI-------PWMSFLLDTNPLKGNYDQLVKLAVA 577
Query: 585 SVFVYYHIHFINELIRFFNPPTKHWETVSALMNAAEATVEGWTSQTRMGLEALLNEHKT- 643
+ + Y IN I F PP ++ L A + E +++ GL A EH++
Sbjct: 578 PINIKYQAPAINNAIDVFKPPES--VRLNQLTALAMSRYEEVKARSATGL-AYAVEHRSR 634
Query: 644 --IDLKLNAASPTIIIPLDAHSWESPCAIIDAGSIKMSSDLVPKQEIKKIKELSVDEYAK 701
+D+++ A + +S E P + D G + + + SVD
Sbjct: 635 LVLDVQIQPAR-IYVSEGGTYSSEKPTLLADMGLL----------SVVTVDNSSVDTSGM 683
Query: 702 IDSDELKRLMFDRFKIKLTDTQLLIGPDMKSSITSINVKQRDNNFTILEKMELDFILDIL 761
L +DRF +KL++ + +++++ V ++++ +L+ LD +
Sbjct: 684 NKMAALMEKAYDRFHVKLSNVVIAFAENVETAENC--VFEKESPLHVLKPTGLDIQIHKS 741
Query: 762 IFPKALNLPRVAASVTLPSLNIFLNDFQYKIIMQLVESCVPYVEDDQEEAXXXXXXXXXX 821
L L ++ LP++ I ++D + +M+L S +P + D++
Sbjct: 742 SIDD-LKLAKMRVIGDLPNIVIGISDDRLIGLMKLGLS-IPTPKADEKTKAEKELEVPVA 799
Query: 822 QLIPLDNIGGSDEALLKHKETLVLKQTKRMMETLSKAELDQTSFQLSLDVSKIEISLLKC 881
++ + E ++ ++ E K + + Q+ LD+ +I ++
Sbjct: 800 KIKDRAKMRTIMEVEEMEEDVTQKEEGGDDDEKEKKKKTSEQQVQIELDLRLNQIGVVVY 859
Query: 882 LEGPTMNSSKLVKLVGEHLSLRLLKSFVKMDFDLSLTELRFEDHISKQTSKGCE---EYM 938
+ ++K+ + L +R FD+ +T IS K + E++
Sbjct: 860 RKDAVFCDVSILKMACK-LQMR--------TFDMVVTAELGSIKISMPEFKSLDEKREHL 910
Query: 939 IFSNGHTKKEKLFDIRGSRVQQIIEYESNLYEVFDISVDLRMSELTLSLIPKSILTLMNF 998
+ + L ++ + + + Y + + SVD R ++L +SL + +L L F
Sbjct: 911 YLIDNDELQGALMTLKFVQANPESPFFATEYALTEQSVDFRFTKLAVSLHQEGVLELKAF 970
Query: 999 ------VLNTF--TDPETPAIPSNVL----------------------RQSQQQDSTPGN 1028
LN PE + ++ +Q+ T G+
Sbjct: 971 GEALQAQLNELQKNTPEEKKVEETARKISRKLSDSVMSIASMSRTPSGKEKRQRKKTVGS 1030
Query: 1029 T------------NVKIFLDGVNIILNDESSKLATFSIHNSELCMDILPQNXXXXXXXXX 1076
+K + +++ + + +I N + I +
Sbjct: 1031 ATQEMDVSRNIKQRIKASFGSLALMIGTQKHLETSLAIENINANVKITEKAMEVVATLRA 1090
Query: 1077 XXXVDETSVDLPKDSVFREIIS---REDNDLAEVI-YETFDPE---TNTNNYDSYLYYRT 1129
D T +V+++++S +ED + + Y+ D + +++ D + R
Sbjct: 1091 ISMKDRT-----PGAVYKKLLSVTGKEDMLRFDFVQYQRTDEQRALMKSSDVDMVVKMRL 1145
Query: 1130 GAMRINFIEHSINKIISFFAKFQKMKVLFDTAHNNAYSKAPDIDTVN----------NMK 1179
MR F+ + +++++ A FQ VL A A ++ N ++
Sbjct: 1146 AQMRFVFLNLWLARLMAWLAPFQNEAVLAAQAAQAAAAEKAATAAQNVKQIMEQSPPRIQ 1205
Query: 1180 LDIVIRTPSISFPKLIDPRNNVYDELIWNMGDLYISNTFTGE----------LGKLVNNV 1229
LD+++ P I P+L R D ++ ++G L + N G+ + L+ +
Sbjct: 1206 LDVILEAPFIVVPRLSTSR----DVIVLHLGRLALKNEIRGDSEYPKAIIDRMDILMTDC 1261
Query: 1230 S--AGIKNAHISSIFNFEGRKVQKLSAVSNLDLRFDVSYNQFHTESDAL--VTVKGYFAP 1285
S G+ N +S++ + + + + + N + L + V +
Sbjct: 1262 SFGMGVMNEDVSAVSS-------SCLILKPISFKLALQRNLTFAVAKELPEIVVDAHIHS 1314
Query: 1286 FYVDLTDLQLQYIYLLSQRIANSFIVSTD--------DDNMEEVEIAALNTNAIIDPQKE 1337
+++D + L Q ++ + D ++E AA A+ P KE
Sbjct: 1315 IEAEMSDADYK---TLMQTLSGNLAEGADLAIPPPPPPSSLESSNTAA----ALTSPGKE 1367
Query: 1338 LHSNQNIFKSEEASSSD---NQKNIEIEFEFNAPEFCLSLFNNTSEKITVKDL-GIARFT 1393
K EA++ + + I F+F + L+ + K+ A
Sbjct: 1368 KEK-----KDREANAGPPVIEKSHTRIVFQFVLDKISAVLYEGEAVNGERKESDAFAALR 1422
Query: 1394 LENFGLSGSAFNTSSANYEMHIKSFTVEDIRYSKTNKHTQLIPKIEGDHHQFMASVDYKE 1453
L+N SG +S + M + +FT++D R KT K ++L+ K +G + + +
Sbjct: 1423 LKNVKTSGKIGEDNSIVFAMSLDAFTMDDERKEKT-KISKLMDK-KGSKDDRFLDMSFNQ 1480
Query: 1454 DKGSSTTTLEVTIDSPKVVLAVEFLLALQSFANSSLNVKQAANFQELSYSKEELPNEALP 1513
D + + + + + + L EFL L F NV Q+ E +P +A+
Sbjct: 1481 D-AEANKQIRLKMSAFFICLCPEFLGCLTRF----FNVPQSEEQLEKQAVTANVPTKAVS 1535
Query: 1514 DDLAVASKVENSNKTFNYSVNVVDS----------AVILLADPSDKQS-EAIVFTIGQFL 1562
+ +S KT + V + VIL+ D +S +A++ +
Sbjct: 1536 ASPSASSTFTGGTKTSSGPPQPVGTLAIDCDMHGVEVILVEDSMHPESTQALILSFNVTA 1595
Query: 1563 VTDHN------ILSIAANNVGLFLSRMGDLNQNRI--RILDDFSSTVMID---GRDSTPD 1611
+ N +++A N+ +F S +N + ++L +++ R +T
Sbjct: 1596 ASHPNEQTKDTKMNVAVENLTIFSSYYQSSRRNEVTYQVLTPVRIEALVNMNTERKTTDA 1655
Query: 1612 ILK-TQIHSSVGPXXXXXXXXXXXXAMEIFNSSLSLAKDEGLMIVXXXXXXXXXXXXKYG 1670
+LK + + + P + ++ S + G K
Sbjct: 1656 VLKMSALDIKMSP--------SIIRLLSAVSAEFSKSSAPG------ETGSISQKAAKLR 1701
Query: 1671 KFSREFKNK---IKKY----APSMVSSLSEISNVMHRNSISDSTKVITKAEKLHSDFAGL 1723
K+ F +K +KY AP ++ E +V + + + ++ K+ D +
Sbjct: 1702 KWPNYFDSKPIDHRKYWFFAAPVAQEAVEEELDVTQEDKSRTDSMIGKESAKV--DIERI 1759
Query: 1724 RVVLIGDMHELPI----ADFNINAFSVDAKDWSTNIDVISTIEPFASAFNYSRSSWEPLI 1779
L +P+ D +NA +A DWS+ + V S + S +N S S WEP+I
Sbjct: 1760 SFTLEAGTGAIPVPLIFLDMLVNA---EAYDWSSAMRVSSGVSVQMSYYNESVSVWEPII 1816
Query: 1780 E------------VFPMTF-HLSKDDENDNA--LIFDIITRKSVEITLSSRTIALLSQI- 1823
E MT +K D +D++ I K + +T++ ++LL+++
Sbjct: 1817 EPVENEKGEFERWKLAMTMKSRNKQDSSDSSPQTEVKIEADKMLNVTVTKSLLSLLNKLS 1876
Query: 1824 PASLTKSHNLKPRGAE-----KPYRIHNDTGHTLNIWIKNSDDDAVNKRANLTKLQSGEI 1878
T + + P P+ + N+TG +++ + +++ V++ GE
Sbjct: 1877 EVFATAAKQITPTKTRHLPGISPFVVLNETG--ISVKVLDTETIRVSENGQAVDATHGEF 1934
Query: 1879 IDWEFEDWR--VVRETLDTEKCMLRASFADDDYSNIIDVDASK-EGDVIHKLYPPVA-GV 1934
+D ++ + V L E+ + + + + + E VIH P V+ G
Sbjct: 1935 VDVFLKNRKSDVEDRRLSIEQEEITGDLKFELAGTVRETKIGRAEKRVIH--LPRVSDGG 1992
Query: 1935 HNRLLISSNLLENNVKLITFGSTLLLRNLTSTEVEYGLSDAGKIKSIGVINPNGT--RSI 1992
H L+++ +EN+ +L+T S + N S VE + G + T ++
Sbjct: 1993 HKWLIVAETTVENSRRLVTLNSHVKFTNHLSYAVEIYSKRDTTLDLFGTVEHGETIPLAV 2052
Query: 1993 PIDSAYQSSFHIRPLTDNASYKWSGIPIFWKMLSES-PLALSCESDLETAGFH-FEVEGS 2050
P+ + +++P+ D Y+ S + W + A+ CE+D F ++
Sbjct: 2053 PLLFSPSGDIYLKPVDD--KYEVSFESLCWHNFEHNRRQAVRCEADSTDGSFSGIYIDSV 2110
Query: 2051 VDK-------DDPLSKIYPRMTVTLSAPLVLENSLPQDISFCLKGRKEEARSEIFLQAGA 2103
V + DD + IY V L PL N+LP DI+ L +K L AG
Sbjct: 2111 VHEEKIQDGIDDQTTSIY---HVHLHPPLEFHNNLPFDINIELPEQK-------VLGAGM 2160
Query: 2104 TIPLHNVSLDSYLLLSIKPDDENFNWSNETLVNSPDVSALEEEHRIFI--TTLDGQKLYL 2161
+ L+ +++ P + E V + ++++ + T +L L
Sbjct: 2161 STLLN--------VVAGSPVKAWLTYLGEKYVLDMSIPEIKKDVEVVALNTETGSDELLL 2212
Query: 2162 SLKYHANGKRAKTISIYAPYVIMNKTTHDL-------SVFSDRQWGVV----KSDVFMKD 2210
L + + K + +YAP+ ++N T L ++ S+ G V KS V ++
Sbjct: 2213 GLHWTSEYGDQK-VYLYAPFWLVNNTDKMLRHVESSGNMLSNTARGCVPCGKKSVVTSQE 2271
Query: 2211 GQKLAR------PKMFSFQYEDYN-RNRAKIKFTETNP-SVPVSFDAIGQSVDISLELLN 2262
+ P + F D + + +A+++ + S D +G + I+ +
Sbjct: 2272 NDDAVQHLPTENPIILPFPAIDLSKKKKARVRIENLSEWSEEFPLDTVGNAARITCKGSE 2331
Query: 2263 HNQECNLGINVKEGEGKYRFTKIVEISPRYIFRNSTSEVIEIMEYGTSSPTILAPKELTP 2322
H+ + + I + + TKIV +P Y+ N +EI E G + +
Sbjct: 2332 HDFDLTVDIKLCQS----GLTKIVTFAPFYLVSNLGKNPMEIREEGQKGWVDIPAETCVG 2387
Query: 2323 LYFLKRTLSKKFVARFAKIPSTWSNPFRLKDVGESFVKMN 2362
++ ++R K R+ + P S F + + E+ M+
Sbjct: 2388 IWPVERKKRKLMCVRYKEEPEAESLLFPITENYETLCHMD 2427
Score = 139 bits (351), Expect = 6e-32
Identities = 118/455 (25%), Positives = 201/455 (43%), Gaps = 22/455 (4%)
Query: 2588 GLEFRFNDSEMYQNLSFKMKWIQIDNQLFGGVYETVLYPTKIPKDSKEIDIHPS--LSGA 2645
GL + S L K+ IQIDNQL ++ VL PK S +D P + +
Sbjct: 2667 GLWACYGKSSQRTRLHAKINHIQIDNQLDACIFPRVLSVVPPPK-SVIVDNTPKPFIELS 2725
Query: 2646 ISKVKDESSSLLNFKMATLLLQEMTIQIDEXXXXXXXX--XXKIPGASWNQAVDDSSSEQ 2703
+ + + E SS+ + +L+QE ++Q+D+ ++ + + + D E
Sbjct: 2726 LLQRQPEFSSIAEIEYGHVLIQEFSVQVDQGLINALLLLISGEVTRKPYGKEMFD---ED 2782
Query: 2704 LFLHPCTVPDFPTTVRSS--KVYFEMLHLQPTLLHLSFVRTDRVNVEEEKSSGNSAINYF 2761
+ + T+ + +T RS K ++ LH+ P ++HLSF + +
Sbjct: 2783 IKICHVTLSETASTYRSQRPKSFYNDLHISPIMMHLSFSQGGTSGDVAASGVSMPIQSEM 2842
Query: 2762 INVLTMALG----NIEGAQIKLNSLLLEHVRVSLPTLVGAIESHYAQQFFYQLHKVLGSA 2817
INVL ++G ++ KL + V S L I SHYA+QF Q++ ++
Sbjct: 2843 INVLLRSVGVTLTELQDVVFKLAYFERKCVFYSPEQLNSEIISHYAKQFIKQVYVLVLGL 2902
Query: 2818 DFLGNPVGFFNNISSGVMDIFYEPYQGYIMNDRPQELGIGIAKGGLSFLKKSIFGFSDSF 2877
D +GNP G ++S+GV D+FY+P+QG I P+E G+A G S ++ G + +
Sbjct: 2903 DIIGNPFGLVRDLSAGVEDLFYQPFQGAIQG--PEEFAAGVALGVQSMFGHAVGGAAGAV 2960
Query: 2878 SKMTGSMAKGLSVAIQDTSFXXXXXXXXXXXGKFGSVGV--GASSFFNNVTSGLTGVALD 2935
++TG++ KG++ D + + G+ G V G+TGV
Sbjct: 2961 GRITGTVGKGVAALTFDDDYMKKRQEDLNRKPQSFGEGMARGLKGLGMGVVGGITGVVTK 3020
Query: 2936 PYSGGAKEXXXXXXXXXXXXXXXLPAKTAIGVLDLASNVSEGIRN-STTLMDIGQIERVR 2994
P G +E + + GV+D AS +R + T + G + R
Sbjct: 3021 PIEGAKQEGGFGFVKGVGKGLIGVVTRPVSGVVDFASGTMNSVRAVAGTNREAGPL---R 3077
Query: 2995 LPRFVSSDKLIKPYNLRDSQGQYWLKTCNGGEYAK 3029
PR + DK++KPY+ D+ G K + GE A+
Sbjct: 3078 PPRVLREDKIVKPYSSGDAYGFKVFKDTDRGELAE 3112
>Hs15619010 [U] KOG1809 Vacuolar protein sorting-associated protein
Length = 3174
Score = 302 bits (773), Expect = 7e-81
Identities = 303/1291 (23%), Positives = 563/1291 (43%), Gaps = 122/1291 (9%)
Query: 1 MLESLVSALLNRFLGAYVENFDPTQLNVGIWNGDVKLRNLRLRKDSLDALDLPIDVKFGY 60
+ ES+V +LNRFLG YV + D +QL++GIW G V L+NL++++++L LD+P VK G+
Sbjct: 2 VFESVVVDVLNRFLGDYVVDLDTSQLSLGIWKGAVALKNLQIKENALSQLDVPFKVKVGH 61
Query: 61 LGELTLLIPWSSLKNKPVKIIIEDVYMLCAPRTPESYNVEEQIERELKVKLQRLADFELA 120
+G L L+IPW +L +PV+ ++E++Y+L P + Y+ ++ ++ ++ K Q L E A
Sbjct: 62 IGNLKLIIPWKNLYTQPVEAVLEEIYLLIVPSSRIKYDPLKEEKQLMEAKQQELKRIEEA 121
Query: 121 NSSKPDINLD-SNRNESFTQSLLTKIVDNLQVTVKNIHMRYEDMNSVFSEGPCAFGISLS 179
D + ++F + L+T+I+ NLQV + +IH+RYED + + P +FGISL
Sbjct: 122 KQKVVDQEQHLPEKQDTFAEKLVTQIIKNLQVKISSIHIRYED-DITNRDKPLSFGISLQ 180
Query: 180 ELSAVSTDESWNPSFISIKQQITHKLATLDSISIYCNTGTESIETDDSEELLIRLRESIA 239
LS +TD+ W P +++ KL LD++ Y N ++ D + L L+ I
Sbjct: 181 NLSMQTTDQYWVPCLHDETEKLVRKLIRLDNLFAYWNVKSQMFYLSDYDNSLDDLKNGIV 240
Query: 240 DNRGAPE-YQYLLKPVRGSARLKMNKAGATE-DAPHIDVQLMFDEFALVLDDCQYKEVLH 297
+ PE Y ++ +P+ +A+L MN+ + AP I++++ A+ + QY ++
Sbjct: 241 NENIVPEGYDFVFRPISANAKLVMNRRSDFDFSAPKINLEIELHNIAIEFNKPQYFSIME 300
Query: 298 NLSKYHWFHKTLKYRQHRPTVKPAADPALWFKYAANCVLS-EIHEKNYKSSWEYIKERRN 356
L + L YR+ +P V W+ YA + VL + + + SW++I++ R
Sbjct: 301 LLESVDMMAQNLPYRKFKPDVPLHHHAREWWAYAIHGVLEVNVCPRLWMWSWKHIRKHRQ 360
Query: 357 KRDEYVSLFKKKLTLPDINDPLPNVEEEKRLHALDVELSFDDIKFFRAFTRREFCQESKF 416
K +Y L+KKKLT P E L L+ L +I R E +++ +
Sbjct: 361 KVKQYKELYKKKLT-----SKKPPGELLVSLEELEKTLDVFNITIARQTAEVE-VKKAGY 414
Query: 417 TQLSETISTNANPQGWFSSWWAPSNAKSDDSL----------TMTDEQRKELYDAIEYDD 466
E + + +GWFS W+ S +++ +T E++ LY+AI Y +
Sbjct: 415 KIYKEGVKDPEDNKGWFSWLWSWSEQNTNEQQPDVQPETLEEMLTPEEKALLYEAIGYSE 474
Query: 467 SN-DPLKSVDIPKDRTTLRVTNLLQKGSLTVMDRTKGHRMCDFIFEESATEFLNRPDXXX 525
+ DP + K L+ L+ S+ + + + + D + EE +T + RP
Sbjct: 475 TAVDP----TLLKTFEALKFFVHLKSMSIVLRENHQKPELVDIVIEEFSTLIVQRPGAQA 530
Query: 526 XXXXXXXXXVE-DGSPHTLYRHIVSPRTKHE-KGGDPLLHLYFDSCPMDESADTFLDIKF 583
G P + PR L + F+ P+DE+ I+
Sbjct: 531 IKFETKIDSFHITGLPDNSEK----PRLLSSLDDAMSLFQITFEINPLDETVSQRCIIEA 586
Query: 584 GSVFVYYHIHFINELIRFFNPPTKHWETVSALMNAAEAT-VEGWTSQTRMGLEALLNEHK 642
+ + Y +N ++ FF PP E A + AA T +E + S+T GL ++ K
Sbjct: 587 EPLEIIYDARTVNSIVEFFRPPK---EVHLAQLTAATLTKLEEFRSKTATGLLYIIETQK 643
Query: 643 TIDLKLNAASPTIIIPLDA-HSWESPCAIIDAGSIKMSSDLVPKQEIKKIKELSVDEYAK 701
+DLK+N + II+P D S S ++D G +K++S K EL + +
Sbjct: 644 VLDLKINLKASYIIVPQDGIFSPTSNLLLLDLGHLKVTS--------KSRSELPDVKQGE 695
Query: 702 IDSDELKRLMFDRFKIKLTDTQLL---IGPDMKSSITSINVKQRDNNFTILEKMELDFIL 758
+ E+ +D F I+LT QLL +G + + + ++V + IL M + L
Sbjct: 696 ANLKEIMDRAYDSFDIQLTSVQLLYSRVGDNWREA-RKLSVSTQH----ILVPMHFNLEL 750
Query: 759 DILIFPKALNLPRVAASVTLPSLNIFLNDFQYKIIMQLVES----------CVPYVEDDQ 808
+ + +P+ LP +++ ++D + + IM+L+ES P
Sbjct: 751 SKAMVFMDVRMPKFKIYGKLPLISLRISDKKLQGIMELIESIPKPEPVTEVSAPVKSFQI 810
Query: 809 EEAXXXXXXXXXXQLIP---LDNIGGSD-------------EALLKHKETLVLKQTKRMM 852
+ + ++IP L ++ D E L+ + +T+++
Sbjct: 811 QTSTSLGTSQISQKIIPLLELPSVSEDDSEEEFFDAPCSPLEEPLQFPTGVKSIRTRKLQ 870
Query: 853 ETLSKAELDQTSFQLSLDVSKIEISLLKCLEGPTMNSSKLVKL-VGEHLSLRL----LKS 907
+ ++ T+F++ +V K+ I + ++ +++ L +G + +R +
Sbjct: 871 K--QDCSVNMTTFKIRFEVPKVLIEFYHLVGDCELSVVEILVLGLGAEIEIRTYDLKANA 928
Query: 908 FVKMDFDLSLTELRFEDHISKQTSKGCEEYMIFSNGHTKKEKLFDIRGSRVQQIIEYESN 967
F+K +F L E + D K Y++ + +T ++ L + + + +S
Sbjct: 929 FLK-EFCLKCPE--YLDENKKPV------YLVTTLDNTMEDLLTLEYVKAEKNVPDLKST 979
Query: 968 LYEVFDISVDLRMSELTLSLIPKSILTLMNFVLNTFTDPETPAIPSNVLRQSQQQD---- 1023
V + + + S L + L +++L +N++ N E + P + + D
Sbjct: 980 YNNVLQL-IKVNFSSLDIHLHTEALLNTINYLHNILPQSEEKSAPVSTTETEDKGDVIKK 1038
Query: 1024 -STPGNTNVKIF-------LDGVNIILNDESSKLATFSIHNSELCMDILPQNXXXXXXXX 1075
+ +TN I L + I + D+ ++ I + M + P
Sbjct: 1039 LALKLSTNEDIITLQILAELSCLQIFIQDQKCNISEIKIEGLDSEMIMRPSETEINAKLR 1098
Query: 1076 XXXXVDETSVDLPKDSVFREIISREDNDLAEVIY---ETFDPETNTNNYDSYLYYRTGAM 1132
+D + K +V+ I +E V Y T+ N D + G +
Sbjct: 1099 NIIVLDSDITAIYKKAVY--ITGKEVFSFKMVSYMDATAGSAYTDMNVVDIQVNLIVGCI 1156
Query: 1133 RINFIEHSINKIISFFAKFQKMKVLFDTAHNNAYSKAPD-----IDTVNNMKLDIVIRTP 1187
+ F+ + I++F FQ K A A A + M LDI I+ P
Sbjct: 1157 EVVFVTKFLYSILAFIDNFQAAKQALAEATVQAAGMAATGVRELAQRSSRMALDINIKAP 1216
Query: 1188 SISFPKLIDPRNNVYDELIWNMGDLYISNTF 1218
+ P+ NV+ + + G + ++NTF
Sbjct: 1217 VVVIPQ-SPVSENVF---VADFGLITMTNTF 1243
Score = 163 bits (412), Expect = 5e-39
Identities = 125/463 (26%), Positives = 208/463 (43%), Gaps = 26/463 (5%)
Query: 2589 LEFRFNDSEMYQNLSFKMKWIQIDNQLFGGVYETVLYPTKIPKDSKEIDIHPSLSGAISK 2648
L+ +N S + ++ IQI NQ+ G V+ V YP K PK S +D P +S
Sbjct: 2630 LKVEYNTSAHQSSFRIQIYRIQIQNQIHGAVFPFVFYPVKPPK-SVTMDSAPKPFTDVSI 2688
Query: 2649 VKDES--SSLLNFKMATLLLQEMTIQIDEXXXXXXXXXXKIPGASWNQAVDDSSSEQLFL 2706
V + S + K +L+QEM +++D + V +++ +LF
Sbjct: 2689 VMRSAGHSQISRIKYFKVLIQEMDLRLD------LGFIYALTDLMTEAEVTENTEVELFH 2742
Query: 2707 HPCTV--PDFPTT--VRSSKV-YFEMLHLQPTLLHLSF-VRTDRVNVEEEKSSGNSAINY 2760
++ T V S+V +E H+ P LHLS + + R ++ K +G +
Sbjct: 2743 KDIEAFKEEYKTASLVDQSQVSLYEYFHISPIKLHLSVSLSSGREEAKDSKQNGGLIPVH 2802
Query: 2761 FINVLTMALG----NIEGAQIKLNSLLLEHVRVSLPTLVGAIESHYAQQFFYQLHKVLGS 2816
+N+L ++G +++ KL L + + L + HY++Q Q++ ++
Sbjct: 2803 SLNLLLKSIGATLTDVQDVVFKLAFFELNYQFHTTSDLQSEVIRHYSKQAIKQMYVLILG 2862
Query: 2817 ADFLGNPVGFFNNISSGVMDIFYEPYQGYIMNDRPQELGIGIAKGGLSFLKKSIFGFSDS 2876
D LGNP G S GV FYEPYQG I P+E G+A G + + ++ G + +
Sbjct: 2863 LDVLGNPFGLIREFSEGVEAFFYEPYQGAIQG--PEEFVEGMALGLKALVGGAVGGLAGA 2920
Query: 2877 FSKMTGSMAKGLSVAIQDTSFXXXXXXXXXX--XGKFGSVGVGASSFFNNVTSGLTGVAL 2934
SK+TG+MAKG++ D + G + G + SG+TG+
Sbjct: 2921 ASKITGAMAKGVAAMTMDEDYQQKRREAMNKQPAGFREGITRGGKGLVSGFVSGITGIVT 2980
Query: 2935 DPYSGGAKEXXXXXXXXXXXXXXXLPAKTAIGVLDLASNVSEGIRNSTTLMDIGQIERVR 2994
P G K A+ G++D+AS+ +GI+ +T + ++E +R
Sbjct: 2981 KPIKGAQKGGAAGFFKGVGKGLVGAVARPTGGIIDMASSTFQGIKRAT---ETSEVESLR 3037
Query: 2995 LPRFVSSDKLIKPYNLRDSQGQYWLKTCNGGEYAKDMYVGHVI 3037
PRF + D +I+PY LRD G L+ G +AK Y HV+
Sbjct: 3038 PPRFFNEDGVIRPYRLRDGTGNQMLQVMENGRFAKYKYFTHVM 3080
Score = 82.0 bits (201), Expect = 1e-14
Identities = 132/672 (19%), Positives = 262/672 (38%), Gaps = 83/672 (12%)
Query: 1703 ISDSTKVITKAEKLHSDFAGLRVVL-IGDMHELPIADFNINAFSVDAKDWSTNIDVISTI 1761
I+ +T+++ K E + + + +VL G H + FS + K+WS+ I++ +
Sbjct: 1709 IAPTTELVPKGEMIKMNIDSIFIVLEAGIGHRTVPMLLAKSRFSGEGKNWSSLINLHCQL 1768
Query: 1762 EPFASAFNYSRSSWEPLIEVFPMTFH--------------------LSKDDENDN----- 1796
E +N WEPL+E + + D E +N
Sbjct: 1769 ELEVHYYNEMFGVWEPLLEPLEIDQTEDFRPWNLGIKMKKKAKMAIVESDPEEENYKVPE 1828
Query: 1797 -ALIFDIITRKSVEITLSSRTIALLSQIPASLTKSHNLKPRGAEK---PYRIHNDTGHTL 1852
+ ++ + ITLS + +L+ + + T++ K P+ I N G T+
Sbjct: 1829 YKTVISFHSKDQLNITLSKCGLVMLNNLVKAFTEAATGSSADFVKDLAPFMILNSLGLTI 1888
Query: 1853 NIWIKNSDDDAVNKRANLTKLQSGEIIDWEFEDWRVVRETLDTEKCMLRASFADD----- 1907
++ +S A L++GE + ++ T D + S +
Sbjct: 1889 SVSPSDSFSVLNIPMAKSYVLKNGESLSMDYI------RTKDNDHFNAMTSLSSKLFFIL 1942
Query: 1908 ----DYSNIIDVDASKEGDVIHKLYPPVAGVHNRLLISSNLLENNVKLITFGSTLLLRNL 1963
++S + +K G ++ + +GV ++ + +E + K +T S + +RN
Sbjct: 1943 LTPVNHSTADKIPLTKVGRRLYTVRHRESGVERSIVCQIDTVEGSKK-VTIRSPVQIRNH 2001
Query: 1964 TSTEVEYGLSDAGKIKSIGVINPNGTRSIPIDSAYQSSFHIRPLTDNASYKWSGIPIFWK 2023
S + D +G +P +IP+ S Y+S ++P +N GI
Sbjct: 2002 FSVPLSVYEGDT----LLGTASPENEFNIPLGS-YRSFIFLKPEDENYQM-CEGIDFEEI 2055
Query: 2024 MLSESPLALSCESDLETAGFHFEVEGSVDKDDPLS-KIYPR------MTVTLSAPLVLEN 2076
+ ++ L + F + +KD+ S +Y + L P++L N
Sbjct: 2056 IKNDGALLKKKCRSKNPSKESFLINIVPEKDNLTSLSVYSEDGWDLPYIMHLWPPILLRN 2115
Query: 2077 SLPQDISFCLKGRKEEARSEIFLQAGATIPLHNVSLDSYLLLSIKPDDENFNWSNETLV- 2135
LP I++ ++G + S L G + + L L D N +W +E +
Sbjct: 2116 LLPYKIAYYIEGIEN---SVFTLSEGHSAQICTAQLGKARLHLKLLDYLNHDWKSEYHIK 2172
Query: 2136 -NSPDVSALEEEHRIFITTLDGQKLYLSLKYHANGKRAKTI-SIYAPYVIMNKTTHDLSV 2193
N D+S + F + +K L + H +T+ + ++PY ++NKT L
Sbjct: 2173 PNQQDISFVS-----FTCVTEMEKTDLDIAVHMTYNTGQTVVAFHSPYWMVNKTGRMLQY 2227
Query: 2194 FSDRQWGVVKSDVFMKDGQKLARPKMFSFQYEDY-NRNRAKIKFTETNPSVPVSFDAIGQ 2252
+D + K +P +FSFQ + N N+ ++ T++ S S D +G
Sbjct: 2228 KAD--------GIHRKHPPNYKKPVLFSFQPNHFFNNNKVQLMVTDSELSNQFSIDTVGS 2279
Query: 2253 SVDISLELLNHNQECNLGINVKEGEGKYRFTKIVEISPRYIFRNSTSEVIEIMEYGTSSP 2312
+ + L + + + I++ + T+IV +P Y+ +N + I + E G
Sbjct: 2280 HGAVKCKGLKMDYQVGVTIDLSS----FNITRIVTFTPFYMIKNKSKYHISVAEEGNDKW 2335
Query: 2313 TILAPKELTPLY 2324
L ++ P +
Sbjct: 2336 LSLDLEQCIPFW 2347
>Hs15619008 [U] KOG1809 Vacuolar protein sorting-associated protein
Length = 3095
Score = 302 bits (773), Expect = 7e-81
Identities = 303/1291 (23%), Positives = 563/1291 (43%), Gaps = 122/1291 (9%)
Query: 1 MLESLVSALLNRFLGAYVENFDPTQLNVGIWNGDVKLRNLRLRKDSLDALDLPIDVKFGY 60
+ ES+V +LNRFLG YV + D +QL++GIW G V L+NL++++++L LD+P VK G+
Sbjct: 2 VFESVVVDVLNRFLGDYVVDLDTSQLSLGIWKGAVALKNLQIKENALSQLDVPFKVKVGH 61
Query: 61 LGELTLLIPWSSLKNKPVKIIIEDVYMLCAPRTPESYNVEEQIERELKVKLQRLADFELA 120
+G L L+IPW +L +PV+ ++E++Y+L P + Y+ ++ ++ ++ K Q L E A
Sbjct: 62 IGNLKLIIPWKNLYTQPVEAVLEEIYLLIVPSSRIKYDPLKEEKQLMEAKQQELKRIEEA 121
Query: 121 NSSKPDINLD-SNRNESFTQSLLTKIVDNLQVTVKNIHMRYEDMNSVFSEGPCAFGISLS 179
D + ++F + L+T+I+ NLQV + +IH+RYED + + P +FGISL
Sbjct: 122 KQKVVDQEQHLPEKQDTFAEKLVTQIIKNLQVKISSIHIRYED-DITNRDKPLSFGISLQ 180
Query: 180 ELSAVSTDESWNPSFISIKQQITHKLATLDSISIYCNTGTESIETDDSEELLIRLRESIA 239
LS +TD+ W P +++ KL LD++ Y N ++ D + L L+ I
Sbjct: 181 NLSMQTTDQYWVPCLHDETEKLVRKLIRLDNLFAYWNVKSQMFYLSDYDNSLDDLKNGIV 240
Query: 240 DNRGAPE-YQYLLKPVRGSARLKMNKAGATE-DAPHIDVQLMFDEFALVLDDCQYKEVLH 297
+ PE Y ++ +P+ +A+L MN+ + AP I++++ A+ + QY ++
Sbjct: 241 NENIVPEGYDFVFRPISANAKLVMNRRSDFDFSAPKINLEIELHNIAIEFNKPQYFSIME 300
Query: 298 NLSKYHWFHKTLKYRQHRPTVKPAADPALWFKYAANCVLS-EIHEKNYKSSWEYIKERRN 356
L + L YR+ +P V W+ YA + VL + + + SW++I++ R
Sbjct: 301 LLESVDMMAQNLPYRKFKPDVPLHHHAREWWAYAIHGVLEVNVCPRLWMWSWKHIRKHRQ 360
Query: 357 KRDEYVSLFKKKLTLPDINDPLPNVEEEKRLHALDVELSFDDIKFFRAFTRREFCQESKF 416
K +Y L+KKKLT P E L L+ L +I R E +++ +
Sbjct: 361 KVKQYKELYKKKLT-----SKKPPGELLVSLEELEKTLDVFNITIARQTAEVE-VKKAGY 414
Query: 417 TQLSETISTNANPQGWFSSWWAPSNAKSDDSL----------TMTDEQRKELYDAIEYDD 466
E + + +GWFS W+ S +++ +T E++ LY+AI Y +
Sbjct: 415 KIYKEGVKDPEDNKGWFSWLWSWSEQNTNEQQPDVQPETLEEMLTPEEKALLYEAIGYSE 474
Query: 467 SN-DPLKSVDIPKDRTTLRVTNLLQKGSLTVMDRTKGHRMCDFIFEESATEFLNRPDXXX 525
+ DP + K L+ L+ S+ + + + + D + EE +T + RP
Sbjct: 475 TAVDP----TLLKTFEALKFFVHLKSMSIVLRENHQKPELVDIVIEEFSTLIVQRPGAQA 530
Query: 526 XXXXXXXXXVE-DGSPHTLYRHIVSPRTKHE-KGGDPLLHLYFDSCPMDESADTFLDIKF 583
G P + PR L + F+ P+DE+ I+
Sbjct: 531 IKFETKIDSFHITGLPDNSEK----PRLLSSLDDAMSLFQITFEINPLDETVSQRCIIEA 586
Query: 584 GSVFVYYHIHFINELIRFFNPPTKHWETVSALMNAAEAT-VEGWTSQTRMGLEALLNEHK 642
+ + Y +N ++ FF PP E A + AA T +E + S+T GL ++ K
Sbjct: 587 EPLEIIYDARTVNSIVEFFRPPK---EVHLAQLTAATLTKLEEFRSKTATGLLYIIETQK 643
Query: 643 TIDLKLNAASPTIIIPLDA-HSWESPCAIIDAGSIKMSSDLVPKQEIKKIKELSVDEYAK 701
+DLK+N + II+P D S S ++D G +K++S K EL + +
Sbjct: 644 VLDLKINLKASYIIVPQDGIFSPTSNLLLLDLGHLKVTS--------KSRSELPDVKQGE 695
Query: 702 IDSDELKRLMFDRFKIKLTDTQLL---IGPDMKSSITSINVKQRDNNFTILEKMELDFIL 758
+ E+ +D F I+LT QLL +G + + + ++V + IL M + L
Sbjct: 696 ANLKEIMDRAYDSFDIQLTSVQLLYSRVGDNWREA-RKLSVSTQH----ILVPMHFNLEL 750
Query: 759 DILIFPKALNLPRVAASVTLPSLNIFLNDFQYKIIMQLVES----------CVPYVEDDQ 808
+ + +P+ LP +++ ++D + + IM+L+ES P
Sbjct: 751 SKAMVFMDVRMPKFKIYGKLPLISLRISDKKLQGIMELIESIPKPEPVTEVSAPVKSFQI 810
Query: 809 EEAXXXXXXXXXXQLIP---LDNIGGSD-------------EALLKHKETLVLKQTKRMM 852
+ + ++IP L ++ D E L+ + +T+++
Sbjct: 811 QTSTSLGTSQISQKIIPLLELPSVSEDDSEEEFFDAPCSPLEEPLQFPTGVKSIRTRKLQ 870
Query: 853 ETLSKAELDQTSFQLSLDVSKIEISLLKCLEGPTMNSSKLVKL-VGEHLSLRL----LKS 907
+ ++ T+F++ +V K+ I + ++ +++ L +G + +R +
Sbjct: 871 K--QDCSVNMTTFKIRFEVPKVLIEFYHLVGDCELSVVEILVLGLGAEIEIRTYDLKANA 928
Query: 908 FVKMDFDLSLTELRFEDHISKQTSKGCEEYMIFSNGHTKKEKLFDIRGSRVQQIIEYESN 967
F+K +F L E + D K Y++ + +T ++ L + + + +S
Sbjct: 929 FLK-EFCLKCPE--YLDENKKPV------YLVTTLDNTMEDLLTLEYVKAEKNVPDLKST 979
Query: 968 LYEVFDISVDLRMSELTLSLIPKSILTLMNFVLNTFTDPETPAIPSNVLRQSQQQD---- 1023
V + + + S L + L +++L +N++ N E + P + + D
Sbjct: 980 YNNVLQL-IKVNFSSLDIHLHTEALLNTINYLHNILPQSEEKSAPVSTTETEDKGDVIKK 1038
Query: 1024 -STPGNTNVKIF-------LDGVNIILNDESSKLATFSIHNSELCMDILPQNXXXXXXXX 1075
+ +TN I L + I + D+ ++ I + M + P
Sbjct: 1039 LALKLSTNEDIITLQILAELSCLQIFIQDQKCNISEIKIEGLDSEMIMRPSETEINAKLR 1098
Query: 1076 XXXXVDETSVDLPKDSVFREIISREDNDLAEVIY---ETFDPETNTNNYDSYLYYRTGAM 1132
+D + K +V+ I +E V Y T+ N D + G +
Sbjct: 1099 NIIVLDSDITAIYKKAVY--ITGKEVFSFKMVSYMDATAGSAYTDMNVVDIQVNLIVGCI 1156
Query: 1133 RINFIEHSINKIISFFAKFQKMKVLFDTAHNNAYSKAPD-----IDTVNNMKLDIVIRTP 1187
+ F+ + I++F FQ K A A A + M LDI I+ P
Sbjct: 1157 EVVFVTKFLYSILAFIDNFQAAKQALAEATVQAAGMAATGVKELAQRSSRMALDINIKAP 1216
Query: 1188 SISFPKLIDPRNNVYDELIWNMGDLYISNTF 1218
+ P+ NV+ + + G + ++NTF
Sbjct: 1217 VVVIPQ-SPVSENVF---VADFGLITMTNTF 1243
Score = 151 bits (382), Expect = 1e-35
Identities = 119/446 (26%), Positives = 200/446 (44%), Gaps = 26/446 (5%)
Query: 2589 LEFRFNDSEMYQNLSFKMKWIQIDNQLFGGVYETVLYPTKIPKDSKEIDIHPSLSGAISK 2648
L+ +N S + ++ IQI NQ+ G V+ V YP K PK S +D P +S
Sbjct: 2630 LKVEYNTSAHQSSFRIQIYRIQIQNQIHGAVFPFVFYPVKPPK-SVTMDSAPKPFTDVSI 2688
Query: 2649 VKDES--SSLLNFKMATLLLQEMTIQIDEXXXXXXXXXXKIPGASWNQAVDDSSSEQLFL 2706
V + S + K +L+QEM +++D + V +++ +LF
Sbjct: 2689 VMRSAGHSQISRIKYFKVLIQEMDLRLD------LGFIYALTDLMTEAEVTENTEVELFH 2742
Query: 2707 HPCTV--PDFPTT--VRSSKV-YFEMLHLQPTLLHLSF-VRTDRVNVEEEKSSGNSAINY 2760
++ T V S+V +E H+ P LHLS + + R ++ K +G +
Sbjct: 2743 KDIEAFKEEYKTASLVDQSQVSLYEYFHISPIKLHLSVSLSSGREEAKDSKQNGGLIPVH 2802
Query: 2761 FINVLTMALG----NIEGAQIKLNSLLLEHVRVSLPTLVGAIESHYAQQFFYQLHKVLGS 2816
+N+L ++G +++ KL L + + L + HY++Q Q++ ++
Sbjct: 2803 SLNLLLKSIGATLTDVQDVVFKLAFFELNYQFHTTSDLQSEVIRHYSKQAIKQMYVLILG 2862
Query: 2817 ADFLGNPVGFFNNISSGVMDIFYEPYQGYIMNDRPQELGIGIAKGGLSFLKKSIFGFSDS 2876
D LGNP G S GV FYEPYQG I P+E G+A G + + ++ G + +
Sbjct: 2863 LDVLGNPFGLIREFSEGVEAFFYEPYQGAIQG--PEEFVEGMALGLKALVGGAVGGLAGA 2920
Query: 2877 FSKMTGSMAKGLSVAIQDTSFXXXXXXXXXX--XGKFGSVGVGASSFFNNVTSGLTGVAL 2934
SK+TG+MAKG++ D + G + G + SG+TG+
Sbjct: 2921 ASKITGAMAKGVAAMTMDEDYQQKRREAMNKQPAGFREGITRGGKGLVSGFVSGITGIVT 2980
Query: 2935 DPYSGGAKEXXXXXXXXXXXXXXXLPAKTAIGVLDLASNVSEGIRNSTTLMDIGQIERVR 2994
P G K A+ G++D+AS+ +GI+ +T + ++E +R
Sbjct: 2981 KPIKGAQKGGAAGFFKGVGKGLVGAVARPTGGIIDMASSTFQGIKRAT---ETSEVESLR 3037
Query: 2995 LPRFVSSDKLIKPYNLRDSQGQYWLK 3020
PRF + D +I+PY LRD G L+
Sbjct: 3038 PPRFFNEDGVIRPYRLRDGTGNQMLQ 3063
Score = 82.0 bits (201), Expect = 1e-14
Identities = 132/672 (19%), Positives = 262/672 (38%), Gaps = 83/672 (12%)
Query: 1703 ISDSTKVITKAEKLHSDFAGLRVVL-IGDMHELPIADFNINAFSVDAKDWSTNIDVISTI 1761
I+ +T+++ K E + + + +VL G H + FS + K+WS+ I++ +
Sbjct: 1709 IAPTTELVPKGEMIKMNIDSIFIVLEAGIGHRTVPMLLAKSRFSGEGKNWSSLINLHCQL 1768
Query: 1762 EPFASAFNYSRSSWEPLIEVFPMTFH--------------------LSKDDENDN----- 1796
E +N WEPL+E + + D E +N
Sbjct: 1769 ELEVHYYNEMFGVWEPLLEPLEIDQTEDFRPWNLGIKMKKKAKMAIVESDPEEENYKVPE 1828
Query: 1797 -ALIFDIITRKSVEITLSSRTIALLSQIPASLTKSHNLKPRGAEK---PYRIHNDTGHTL 1852
+ ++ + ITLS + +L+ + + T++ K P+ I N G T+
Sbjct: 1829 YKTVISFHSKDQLNITLSKCGLVMLNNLVKAFTEAATGSSADFVKDLAPFMILNSLGLTI 1888
Query: 1853 NIWIKNSDDDAVNKRANLTKLQSGEIIDWEFEDWRVVRETLDTEKCMLRASFADD----- 1907
++ +S A L++GE + ++ T D + S +
Sbjct: 1889 SVSPSDSFSVLNIPMAKSYVLKNGESLSMDYI------RTKDNDHFNAMTSLSSKLFFIL 1942
Query: 1908 ----DYSNIIDVDASKEGDVIHKLYPPVAGVHNRLLISSNLLENNVKLITFGSTLLLRNL 1963
++S + +K G ++ + +GV ++ + +E + K +T S + +RN
Sbjct: 1943 LTPVNHSTADKIPLTKVGRRLYTVRHRESGVERSIVCQIDTVEGSKK-VTIRSPVQIRNH 2001
Query: 1964 TSTEVEYGLSDAGKIKSIGVINPNGTRSIPIDSAYQSSFHIRPLTDNASYKWSGIPIFWK 2023
S + D +G +P +IP+ S Y+S ++P +N GI
Sbjct: 2002 FSVPLSVYEGDT----LLGTASPENEFNIPLGS-YRSFIFLKPEDENYQM-CEGIDFEEI 2055
Query: 2024 MLSESPLALSCESDLETAGFHFEVEGSVDKDDPLS-KIYPR------MTVTLSAPLVLEN 2076
+ ++ L + F + +KD+ S +Y + L P++L N
Sbjct: 2056 IKNDGALLKKKCRSKNPSKESFLINIVPEKDNLTSLSVYSEDGWDLPYIMHLWPPILLRN 2115
Query: 2077 SLPQDISFCLKGRKEEARSEIFLQAGATIPLHNVSLDSYLLLSIKPDDENFNWSNETLV- 2135
LP I++ ++G + S L G + + L L D N +W +E +
Sbjct: 2116 LLPYKIAYYIEGIEN---SVFTLSEGHSAQICTAQLGKARLHLKLLDYLNHDWKSEYHIK 2172
Query: 2136 -NSPDVSALEEEHRIFITTLDGQKLYLSLKYHANGKRAKTI-SIYAPYVIMNKTTHDLSV 2193
N D+S + F + +K L + H +T+ + ++PY ++NKT L
Sbjct: 2173 PNQQDISFVS-----FTCVTEMEKTDLDIAVHMTYNTGQTVVAFHSPYWMVNKTGRMLQY 2227
Query: 2194 FSDRQWGVVKSDVFMKDGQKLARPKMFSFQYEDY-NRNRAKIKFTETNPSVPVSFDAIGQ 2252
+D + K +P +FSFQ + N N+ ++ T++ S S D +G
Sbjct: 2228 KAD--------GIHRKHPPNYKKPVLFSFQPNHFFNNNKVQLMVTDSELSNQFSIDTVGS 2279
Query: 2253 SVDISLELLNHNQECNLGINVKEGEGKYRFTKIVEISPRYIFRNSTSEVIEIMEYGTSSP 2312
+ + L + + + I++ + T+IV +P Y+ +N + I + E G
Sbjct: 2280 HGAVKCKGLKMDYQVGVTIDLSS----FNITRIVTFTPFYMIKNKSKYHISVAEEGNDKW 2335
Query: 2313 TILAPKELTPLY 2324
L ++ P +
Sbjct: 2336 LSLDLEQCIPFW 2347
>Hs20550856 [U] KOG1809 Vacuolar protein sorting-associated protein
Length = 1422
Score = 280 bits (716), Expect = 3e-74
Identities = 306/1332 (22%), Positives = 574/1332 (42%), Gaps = 170/1332 (12%)
Query: 1 MLESLVSALLNRFLGAYVENFDPTQLNVGIWNGDVKLRNLRLRKDSLDALDLPIDVKFGY 60
+LES+V+ LLNRFLG YVEN + +QL +GIW G+V L NL++++++L LD+P VK G
Sbjct: 2 VLESVVADLLNRFLGDYVENLNKSQLKLGIWGGNVALDNLQIKENALSELDVPFKVKAGQ 61
Query: 61 LGELTLLIPWSSLKNKPVKIIIEDVYMLCAPRTPESYNV--EEQIERELKVK-------- 110
+ +LTL IPW +L + V +E +Y+L P Y+ EE+ +++K K
Sbjct: 62 IDKLTLKIPWKNLYGEAVVATLEGLYLLVVPGASIKYDAVKEEKSLQDVKQKELSRIEEA 121
Query: 111 LQRLAD---------FELANS------------------SKPDINLDSNRN-------ES 136
LQ+ A+ + L N KP LD +++ ++
Sbjct: 122 LQKAAEKGTHSGEFIYGLENFVYKDIKPGRKRKKHKKHFKKPFKGLDRSKDKPKEAKKDT 181
Query: 137 FTQSLLTKIVDNLQVTVKNIHMRYEDMNSVFSEGPCAFGISLSELSAVSTDESWNPSFIS 196
F + L T+++ N+QV + +IH++YED + + P +FG++L ELS ++ +E W P ++
Sbjct: 182 FVEKLATQVIKNVQVKITDIHIKYED-DVTDPKRPLSFGVTLGELSLLTANEHWTPCILN 240
Query: 197 IKQQITHKLATLDSISIYCNTGTESIETDDSEELLIRLR-ESIADNRGAPEYQYLLKPVR 255
+I +KL LDS+S Y N E++L +L+ E + P YQY+ +P+
Sbjct: 241 EADKIIYKLIRLDSLSAYWNVNCSMSYQRSREQILDQLKNEILTSGNIPPNYQYIFQPIS 300
Query: 256 GSARLKMNKAGATE-DAPHIDVQLMFDEFALVLDDCQYKEVLHNLSKYHWFHKTLKYRQH 314
SA+L MN +E P +D + A+ L QY ++ L + + YR++
Sbjct: 301 ASAKLYMNPYAESELKTPKLDCNIEIQNIAIELTKPQYLSMIDLLESVDYMVRNAPYRKY 360
Query: 315 RPTVKPAADPALWFKYAANCVLSEIHEKNYKS--SWEYIKERRNKRDEYVSLFKKKLTLP 372
+P + + W+KYA + VL E+H + Y SW IK+ R Y +K KLT
Sbjct: 361 KPYLPLHTNGRRWWKYAIDSVL-EVHIRRYTQMWSWSNIKKHRQLLKSYKIAYKNKLTQS 419
Query: 373 DINDPLPNVEEEKRLHALDVELSFDDIKFFRAFTRREFCQESKFTQLSETISTNANPQGW 432
+++ E +K + L+ L +I R + E + + + ++ T GW
Sbjct: 420 KVSE-----EIQKEIQDLEKTLDVFNIILARQQAQVEVIRSGQKLR-KKSADTGEKRGGW 473
Query: 433 FSSWWAPSNAKSDDSLT---------MTDEQRKELYDAIEYDDSNDPLKSVDIPKDRTTL 483
FS W +K D + MT E++ +L+ AI Y +S ++ +PK
Sbjct: 474 FSGLWGKKESKKKDEESLIPETIDDLMTPEEKDKLFTAIGYSEST---HNLTLPKQYVAH 530
Query: 484 RVTNLLQKGSLTVMDRTKGHRMCDFIFEESATEFLNRPDXXXXXXXXXXXXVEDGSPHTL 543
+T L S+T+ + + T+ RP +E L
Sbjct: 531 IMTLKLVSTSVTIRENKNIPEILKIQIIGLGTQVSQRP---GAQALKVEAKLEHWYITGL 587
Query: 544 YRHIVSPRTKHEKGG--DPLLHLYFDSCPMDESADTFLDIKFGSVFVYYHIHFINELIRF 601
+ + P G LL + F++ P D AD L ++ V V Y +N ++ F
Sbjct: 588 RQQDIVPSLVASIGDTTSSLLKIKFETNPEDSPADQTLIVQSQPVEVIYDAKTVNAVVEF 647
Query: 602 FNPPTKHWETVSALMNAAEATVEGWTSQTRMGLEALLNEHKTIDLKLNAASPTIIIPLDA 661
F + + + +A +E +T GL ++ K +DL++N +++P
Sbjct: 648 FQ--SNKGLDLEQITSATLMKLEEIKERTATGLTHIIETRKVLDLRINLKPSYLVVPQTG 705
Query: 662 -HSWESPCAIIDAGSIKMSSDLVPKQEIKKIKELSVDEYAKIDSDELKRLMFDRFKIKLT 720
H +S I+D G+ +++S K+ + + +E+ +D+F +++
Sbjct: 706 FHHEKSDLLILDFGTFQLNS-----------KDQGLQKTTNSSLEEIMDKAYDKFDVEIK 754
Query: 721 DTQLLIGPDMKSSITSINVK-QRDNNFTILEKMELDFILDILIFPKALNLPRVAASVTLP 779
+ QLL ++ T + Q + IL+ M++ L + K + + R S LP
Sbjct: 755 NVQLLFA---RAEETWKKCRFQHPSTMHILQPMDIHVELAKAMVEKDIRMARFKVSGGLP 811
Query: 780 SLNIFLNDFQYKIIMQLVESCVPYVEDDQEEAXXXXXXXXXXQLIPLDNIGGSDEALLKH 839
+++ ++D + K ++ L+ S +P + ++ Q+ + I G + LL
Sbjct: 812 LMHVRISDQKMKDVLYLMNS-IPLPQKSSAQS-------PERQVSSIPIISGGTKGLL-- 861
Query: 840 KETLVLKQTKRMMETLSKAELDQTSFQLSLDVSKIEISLLKCLEGPTMNSSKLVKLVGEH 899
T +++T+ ++E D F D E K ++G + K ++ E
Sbjct: 862 -------GTSLLLDTV-ESESDDEYF----DAEDGEPQTCKSMKGSEL--KKAAEVPNEE 907
Query: 900 LSLRLLKSFVKMDFDLSLTELRFEDH---ISKQTSKGCEEYM----IFSNGHTKKEKL-- 950
L LLK +K + L T+ + E+ + T G E M + + KK L
Sbjct: 908 LINLLLKFEIK-EVILEFTKQQKEEDTILVFNVTQLGTEATMRTFDLTVVSYLKKISLDY 966
Query: 951 FDIRGSRVQQI---------------IEY---------ESNLYEVFDISVDLRMSELTLS 986
+I GS+ + + +EY + + +V + S L L
Sbjct: 967 HEIEGSKRKPLHLISSSDKPGLDLLKVEYIKADKNGPSFQTAFGKTEQTVKVAFSSLNLL 1026
Query: 987 LIPKSILTLMNFVLNTF-TDPETPAIPSNV--LRQSQQQDSTPGNTNV----------KI 1033
L ++++ +N++ +D ++ ++ V + QQ++ST V ++
Sbjct: 1027 LQTQALVASINYLTTIIPSDDQSISVAKEVQISTEKQQKNSTLPKAIVSSRDSDIIDFRL 1086
Query: 1034 F--LDGVNIILNDESSKLATFSIH--NSELCMDILPQNXXXXXXXXXXXXVDETSVDLPK 1089
F L+ +I+ +E + +A I +S L + Q+ VD +V
Sbjct: 1087 FAKLNAFCVIVCNEKNNIAEIKIQGLDSSLSLQSRKQSLFARLENIIVTDVDPKTVHKKA 1146
Query: 1090 DSVFREIISREDNDLAEVIYETFDPETNTNNYDSYLYYRTGAMRINFIEHSINKIISFFA 1149
S+ + R + DL E D T+ + D L G ++I ++ + +++F
Sbjct: 1147 VSIMGNEVFRFNLDLYPDATEG-DLYTDMSKVDGVLSLNVGCIQIVYLHKFLMSLLNFLN 1205
Query: 1150 KFQKMKVLFDTAHNNAYSK-APDIDTVNNMKLDIVIRTPSISFPKLIDPRNNV-YDELIW 1207
FQ K A A + A + + + I + P ++ P++++ + ++
Sbjct: 1206 NFQTAKESLSAATAQAAERAATSVKDLAQRSFRVSINI-DLKAPVIVIPQSSISTNAVVV 1264
Query: 1208 NMGDLYISNTFT 1219
++G + + N F+
Sbjct: 1265 DLGLIRVHNQFS 1276
>7304192 [U] KOG1809 Vacuolar protein sorting-associated protein
Length = 3242
Score = 204 bits (519), Expect = 2e-51
Identities = 112/321 (34%), Positives = 189/321 (57%), Gaps = 10/321 (3%)
Query: 1 MLESLVSALLNRFLGAYVENFDPTQLNVGIWNGDVKLRNLRLRKDSLDALDLPIDVKFGY 60
+ E++V+ +LN+ LG Y+EN D QL +GIW GDV L+NL++R+++LD LDLP+ + +GY
Sbjct: 2 VFEAVVADVLNKVLGDYIENLDRNQLKIGIWGGDVVLQNLKIRENALDELDLPVQLIYGY 61
Query: 61 LGELTLLIPWSSLKNKPVKIIIEDVYMLCAPRTPESYNVEEQIERELKVKLQRLADFELA 120
LG+L L IPW +L ++PV + IED+Y+L +P YN E++ + E+ +K L E A
Sbjct: 62 LGKLVLKIPWKNLYSQPVIVNIEDLYVLVSPNNNVQYNAEKEAKYEMDLKKAALDALEAA 121
Query: 121 NSSKPDINLDSNRNES-FTQSLLTKIVDNLQVTVKNIHMRYEDMNSVFSEGPCAFGISLS 179
K ++ +D + ++ F + L +IV+NLQV + N+H+RYED + S P +FGISL
Sbjct: 122 R--KKELEMDQPKADAGFAEKLTAQIVNNLQVQITNVHLRYEDTTTTGS--PFSFGISLH 177
Query: 180 ELSAVSTDESWNPSFISIKQQITHKLATLDSISIYCNTGTESIETDDSEELLIRLRESIA 239
EL +TD W +++ + K+A L +S Y N G + + ++ +L + + +IA
Sbjct: 178 ELELYTTDCDWEKCYMAQQASQVFKIANLSCLSAYLNCGGQ-LYANNKSDLSQQFKTNIA 236
Query: 240 DNRGAPEYQYLLKPVRGSARLKMNKAGATED----APHIDVQLMFDEFALVLDDCQYKEV 295
P Y Y+L P+ +A+LK+N +D P ID+ L ++ + L + Q+ +
Sbjct: 237 CKETKPNYNYVLGPISCNAKLKLNMNPELDDPPFEKPKIDLTLEMEKLNVGLTNTQFDNL 296
Query: 296 LHNLSKYHWFHKTLKYRQHRP 316
+ + + YR++RP
Sbjct: 297 MKLGDAMNRQQLGIPYRKYRP 317
Score = 139 bits (349), Expect = 1e-31
Identities = 112/447 (25%), Positives = 186/447 (41%), Gaps = 34/447 (7%)
Query: 2596 SEMYQNLSFKMKWIQIDNQLFGGVYETVLYPTKIPKD-SKEIDIHPSLSGAISKVKDESS 2654
S L K+ IQ+DNQ ++ VL P PK + + P + ++ + +S
Sbjct: 2698 SPFQSQLHVKINRIQVDNQFLDPIFPVVLAPIPPPKSVASTTSLKPFIECSMVQRIMPNS 2757
Query: 2655 SLLNFKMATLLLQEMTIQIDEXXXXXXXXXXKIPGASWNQAVDDSSSEQLFLHPCTVPDF 2714
++ FK A +L+QE ++D + + V D ++ + F +
Sbjct: 2758 TVRQFKYARILIQEFLFKVDLNFLTAIAEM-------FAKEVSDEAAAKQFRQDVESIEL 2810
Query: 2715 PTT-------VRSSKVYFEMLHLQPTLLHLSFVRTDRVNVEEEKSSGNSAINYFINVLTM 2767
P + + K +++ LHL P +H+SF S A+ F+ L
Sbjct: 2811 PLSAFFEEHSLEEQKSFYDNLHLGPLKIHVSFSMA---------GSDTKALPGFLGSLVQ 2861
Query: 2768 ALG----NIEGAQIKLNSLLLEHVRVSLPTLVGAIESHYAQQFFYQLHKVLGSADFLGNP 2823
+G ++ +L E+ S L+ I SHY Q QL+ ++ D LGNP
Sbjct: 2862 GVGVTLTDVNDVVFRLAFFEREYQFFSQKQLINEITSHYTGQALKQLYVLVLGLDVLGNP 2921
Query: 2824 VGFFNNISSGVMDIFYEPYQGYIMNDRPQELGIGIAKGGLSFLKKSIFGFSDSFSKMTGS 2883
G + GV D+FYEP+QG I P E G+ G S ++ G + + SK+TG+
Sbjct: 2922 YGLVVGLKKGVEDLFYEPFQGAIQG--PGEFAEGLVLGVKSLFGHTVGGAAGAVSKITGA 2979
Query: 2884 MAKGLSVAIQDTSFXXXXXXXXXXXGKFGSVGVGASS--FFNNVTSGLTGVALDPYSGGA 2941
M KGL+ D + K G+ SS G+TGV P +G
Sbjct: 2980 MGKGLAALTFDEDYQKKRRQGIQNKPKNFHEGLARSSKGLVMGFVDGVTGVVTKPVTGAR 3039
Query: 2942 KEXXXXXXXXXXXXXXXLPAKTAIGVLDLASNVSEGIRNSTTLMDIGQIERVRLPRFVSS 3001
L A+ GV+D AS E ++ + + ++R+R PRF
Sbjct: 3040 DNGVEGFFKGLGKGAIGLVARPTAGVVDFASGSFEAVKRAADASE--DVKRMRPPRFQHY 3097
Query: 3002 DKLIKPYNLRDSQGQYWLKTCNGGEYA 3028
D +++PY L ++ G +K + G++A
Sbjct: 3098 DFVLRPYCLMEATGNKIMKETDKGKFA 3124
Score = 73.2 bits (178), Expect = 6e-12
Identities = 134/667 (20%), Positives = 255/667 (38%), Gaps = 142/667 (21%)
Query: 431 GWFSSWWAPSNAKSDDSLT-----------MTDEQRKELYDAIEYDDSNDPLKSVDIPKD 479
GWFS W AK DD T MT E+++++Y AI Y ++ P D+P+
Sbjct: 353 GWFSGWGWGGGAKKDDQTTSQKLVEKFEAAMTSEEKEKMYRAIGYQENAKP---TDLPES 409
Query: 480 RTTLRVTNLL-----------QKGSLTVMDRTKGHRMCDFIFEESATEFLNRPDXXXXXX 528
+R+ L + S D + + F + RP
Sbjct: 410 YEAIRMNFKLIALEVGLYKDERNSSAATKDFHELPSLVLLNFSMATALITQRPAAEAISI 469
Query: 529 XXXXXXVEDGSPHTLYRHIVSPRTKHEKGGDP--LLHLYFDSCPMDESADTFLDIKFGSV 586
++ L R+ +P K D LL ++F++ P+D+ D + + +
Sbjct: 470 IAGMREIKVTG---LTRNDYTPLLVESKITDEFNLLEVFFETNPLDKLCDQRVKVVARPL 526
Query: 587 FVYYHIHFINELIRFFNPPTKHWETVSALMNAAEATVEGWTSQTRMGLEALLNEHKTIDL 646
+ Y I LI F P T+S +AA + + ++ G++ ++++ +D+
Sbjct: 527 QITYDAPTILALINAFQTPGD--VTLSKFEDAASTKISNFKERSATGMQYMIDKKAVLDV 584
Query: 647 KLNAASPTIIIPLDA--HSWESPCAIIDAGSIKMSSDLVPKQEIKKIKELSVDEYAKIDS 704
+ +++P + ++ G + +SS P++E K++ L A D
Sbjct: 585 DILLMPNILVVPHKGVYDAGNVSLLVVSMGQVHLSSQ--PRRESNKLQHLF---SAGEDK 639
Query: 705 DE-LKRLM---FDRFKIKLTDTQLLI---GPDMKSSITSINVKQRDNNFTILEKMELDFI 757
DE LK +M +DRF + + D Q+L+ G ++++ N +L + L
Sbjct: 640 DEILKTVMENAYDRFTVAVDDVQMLVVRAGEPWQNALAEAN----STEMHVLRPVSLKVT 695
Query: 758 LDILIFPKALNLPRVAASVTLPSLNIFLNDFQYKIIMQLVESCVPYVEDDQEEAXXXXXX 817
+ + LP + + LP++ + +++ + + +++ S
Sbjct: 696 AALCVVDNDPRLPNIKVDIDLPAILVNVSEDRIFLAIKVATS------------------ 737
Query: 818 XXXXQLIPLDNIGGSDEALLKHKETLVLKQTKRMMETLSKAELDQTSFQLSLDVSKIEIS 877
IPL + KE R+ +T S++ + ++F ++ +V KI
Sbjct: 738 ------IPLP----------EQKE-----PASRLTQTNSRSSMSISNF-INKEVKKI--- 772
Query: 878 LLKCLEGPTMNSSKLVK--LVGEHLSLRLLKSFVKMDFDLSLTELRFEDHISKQTSKGCE 935
GP+ + S K L+ E + + +D + SL E+ F + Q+S+ CE
Sbjct: 773 ------GPSASGSSASKDPLLDE------IIQYTSLDVNFSLGEINF---VLFQSSRKCE 817
Query: 936 E------YMIFSNGHTKKEKLFDIRGSRVQQIIEYESNLYEVFDISVDLRMSELTLSLIP 989
+ +G +L + +Q+ IE +S+D+R E
Sbjct: 818 TSPDVSIEFLTPDGDVLPSQLTE----NIQEPIEELPPTPPQQILSIDIRRLE------- 866
Query: 990 KSILTLMNFVLNTFTDPETPAIPSNVLRQSQQQDS---------TPGNTNVKIFLDGVNI 1040
+FV T+ T + LRQ QDS TP N +L V+
Sbjct: 867 ------AHFVSKTYESVATVKLGDINLRQYDCQDSDMDVLDVIYTPKQENSSNYLFTVSC 920
Query: 1041 ILNDESS 1047
+ D+SS
Sbjct: 921 TIADKSS 927
Score = 71.2 bits (173), Expect = 2e-11
Identities = 276/1470 (18%), Positives = 547/1470 (36%), Gaps = 243/1470 (16%)
Query: 1085 VDLPKDSVFREIISREDNDL--AEVIYETFDPETNTNNYDSYLYYRTGAMRINFIEHSIN 1142
+DL ++ + I+S D +++ + + N+ D + G M+I F+ +
Sbjct: 1081 LDLNPYTIHKNILSIVGKDAFNCQIVIYNKEETQDYNSDDMKITVDIGCMKIIFLNWFVA 1140
Query: 1143 KIISFFAKFQKMKVLFD----TAHNNAYSKAPDI-DTVNNMKLDIVIRTPSISFPKLIDP 1197
+++F F + A +A KA D +T MKL+I I+ P I P
Sbjct: 1141 GVMNFLNNFTAAQATISQAGAAAAESARQKAMDAYETATRMKLNIRIKAPIIIVPIGSQD 1200
Query: 1198 RNNVYDELIWNMGDLYISNTFTG------ELGKLVNNVSAGIKNAHISSIFNFEGRKVQK 1251
RN L+ ++G L ++N E +++ + I + IS I +G +
Sbjct: 1201 RN----ALLLDLGLLELTNNTVEVAVAEEERLAVIDEIKLQICDVKISKIVLLDGNE--- 1253
Query: 1252 LSAVSNLDLR--FDVSYNQFHTESDALVTVKGYFAPFYVDLTDLQLQYIYLLSQRIANSF 1309
S V +D F +N + S L + +Y D+ +L L S R+ +
Sbjct: 1254 -STVDEVDAEVGFLSKFNMMNPMSCTLSITRNLSYTWYRDVPELNL------SGRLKSIE 1306
Query: 1310 IVSTDDDNMEEVEIAALNTN---------------AIIDPQKELHSNQNIFKSEEASSSD 1354
+ DD + + N N A + P++ + ++ + S
Sbjct: 1307 LTLFADDYALVMLVLNRNLNEGLEEFPPSEEAPQEAQVRPERRNSRAGRLSRTVQVSPIR 1366
Query: 1355 NQKNIEIEFEFNAPEFCLSLFNNTSEKITVKDLGIARFTLENFGLSGSAFNTSSANYEMH 1414
+ + I+F F ++L + G+ARF + + G+ + + + +
Sbjct: 1367 EKIHESIKFNFQFDGVVINLMEG-------EGAGLARFGIYFLSVKGTKLDNGTLSTSVV 1419
Query: 1415 IKSFTVEDIRYSKTNKHTQLI-------PKIEGDH--------HQFMASVD--YKEDKGS 1457
+ + ++D+R + ++ Q + PK++ D FM V KED
Sbjct: 1420 LCNIQMDDMRSNSKSQIRQYLSRKDWVQPKLDTDEIIDACYNERNFMVDVTAIIKEDD-- 1477
Query: 1458 STTTLEVTIDSPKVVLAVEFLLALQSFAN--------SSLNVKQAANFQELSYSKEELPN 1509
T EV + +++ ++FLL L +F S+ +K A + +K + +
Sbjct: 1478 --TFAEVRVRGFDLIVCIDFLLKLTTFLTLPPEENPRESVYIKPAPVSETARDTKHSIRS 1535
Query: 1510 EAL--PDDLAV--ASKVENSNKTFNYSVNVVDSAVILLADPSDKQSEAIVFTIGQFL--- 1562
A+ +L +S E N+ N +++ + +IL+ + D + I+F L
Sbjct: 1536 SAILAAQELVPVESSSHEVPNRKMNLILHIDEPDIILVENLEDLNTSCIIFNAQVHLNYR 1595
Query: 1563 -VTDHNILSIAANNVGLFLSRMGDLNQNRIRILDDFSSTVMIDGRDSTPDILKTQIHSSV 1621
+ D I++ + + +++ L + R +I + STP+ + +H S+
Sbjct: 1596 SINDKQIVNGQIDALKMYMCAF--LPERREMTRHYILHPCVISLQGSTPE--EEGMHISL 1651
Query: 1622 GPXXXXXXXXXXXXAMEIFNSSLSLAKDEGLMIVXXXXXXXXXXXXKYGKFSREFKNKIK 1681
+E+ N ++ L+ G M Y + +
Sbjct: 1652 --KLSDIIINVSPATIELLNKAM-LSVSSGTM----TKCAIAEESRNYSNLWHQHHFHSR 1704
Query: 1682 KYAPSMVSSLSEISNVMHRNSISDSTKVITKAEKLHSDFAGLRVVLIGDM--HELPIADF 1739
Y + V + R+ +D+ K K EK + + +V+ + + P+
Sbjct: 1705 TYWFTKVEQGVDALEAEQRSVSTDNEK--QKTEKCVIEIPSITLVIESGVGYYTKPLISL 1762
Query: 1740 NINAFSVDAKDWS----------TNIDVISTIEPFASAFNYSRSSWEPLIEV-FPMTFHL 1788
+ +V +WS N+ +I E + WE E+
Sbjct: 1763 DTRITAV-FNNWSRSLTAHGSLTLNMPIIELNEVIGRNGVREYTPWELKFEMGMEKVQSE 1821
Query: 1789 SKDDENDNALIFDIITRKSVEITLSSRTIALLSQIPASLTKS---HNLKPRGAEKPYRIH 1845
+DD A+ +I + +++EITLS + LLS++ + +++ + L PY +
Sbjct: 1822 LEDDAEQQAMHMNIHSAETLEITLSKTCLGLLSELAEAFSQAIDQNGLTKPDIVAPYVLE 1881
Query: 1846 NDTGHTLNIWIK---------NSDDDAVNKRANLTKLQSGEIIDWEFEDWRVV----RET 1892
NDTG +N+ ++ + V + L + E +D + R
Sbjct: 1882 NDTGFDVNLNLRKGIFTLHEVHRGGTPVGANSTLLMVAQSEEVDPSVIKTCTISTGGRAY 1941
Query: 1893 LDTEKCMLRASFADDDYSNIIDVDASKEGDVIHKLYPPVAGVHNRL-------------L 1939
L T+ + +DY+ + + GD+ ++ PV+ R +
Sbjct: 1942 LQTKDLSTLSEEDSEDYTLYVTI-----GDINKEIALPVSKSDTRFFNLMRSTSHEPWGI 1996
Query: 1940 ISSNLLENNVKLITFGSTLLLRNLTSTEVE-YGLSDAGKIKS-----IGVINPNGTRSIP 1993
IS E + + + N +T + Y + A + +G + P +P
Sbjct: 1997 ISEVKQEYGTTKVNIHGVVSVHNHFTTGLNIYRRNPAPTAQCFEDIFVGRVRPGEVFHVP 2056
Query: 1994 IDSAYQSS----FHIRPLTDNA-SYKWSGIPIFWKMLSE---------SPLALSCESDLE 2039
+ + Y S F +R + W+ P + PL ++
Sbjct: 2057 LHAIYAESKDLFFSMRGYRRSVQGISWASNPSDLNYSHQLHCDPTNTFEPLIMNARRSKS 2116
Query: 2040 TAGFHFEVEGSVDKDDPLSKIYPRMTVTLSAPLVLENSLPQDISFCLKG---RKEEA--- 2093
F + +K LS Y T+ L PL L NSLP +I + G RKE+
Sbjct: 2117 EVYFE-----NTNKYTLLSAFY---TIHLRPPLYLRNSLPINIQVSVAGCSVRKEDGLDA 2168
Query: 2094 -----------RSEIFLQAGATIPLHN---VSLDSYLLLSIKPDDENF-----------N 2128
R E FL G P+++ + L + L S + ++F +
Sbjct: 2169 QSSQRFVDRGYRKEDFLDYGEK-PVNSGDVLHLPTVRLASKGKESKSFLVVRLVQYLEKD 2227
Query: 2129 WSNETLV--NSPDV-----SALEEEHRIFITTLDGQKLYLSLKYHANGKRAKTISIYAPY 2181
WS T + + DV S+ + E ++ LY+ + N + +++++P+
Sbjct: 2228 WSCATEIWDYTDDVITWTFSSYDSEMKV------DMDLYVKTE---NRHGSLMLTLFSPF 2278
Query: 2182 VIMNKTTHDLSVFSDRQWGVVKSDVFMKDGQKLARPKMFSFQYE-DYNRNRAKIKFTETN 2240
++NKT L+ S+ S + + + P +F+F+ + +++ +A I+
Sbjct: 2279 WMINKTGMMLTYKSE-----TTSVEVLYHPPEYSGPILFTFRDKLFFDKKKASIRIDNGQ 2333
Query: 2241 PSVPVSFDAIGQSVDISLELLNHNQECNLGINVKEGEGKYRFTKIVEISPRYIFRNSTSE 2300
S + D G ++ +NQ+ +G++ + TK + P YI N
Sbjct: 2334 WSEKIPLDVAGSVGEVI--CFANNQKYPVGVHNHLTQNS--LTKQITFIPFYIVCNKCHF 2389
Query: 2301 VIEIMEYG-TSSPTI-LAPKELTPLYFLKRTLSKKFVARFAKIPSTWSNPFRLKDVGESF 2358
IE+ E + P + L P E+ PL+ T + V KI + F +V +
Sbjct: 2390 DIELQEQSRPADPWLHLEPNEMEPLWPRNDTKNNLVVRVDGKI----TPAFDFTEVICTL 2445
Query: 2359 VKMNITDAAQRLIKMDISLEGATVFINAVD 2388
+K+ D+ I +D+ V+I D
Sbjct: 2446 LKLE--DSKYGGINVDVQTTEGGVYITFTD 2473
>At1g48090 [U] KOG1809 Vacuolar protein sorting-associated protein
Length = 4099
Score = 144 bits (362), Expect = 3e-33
Identities = 191/893 (21%), Positives = 364/893 (40%), Gaps = 165/893 (18%)
Query: 9 LLNRFLGAYVENFDPTQLNVGIWNGDVKLRNLRLRKDSLDALDLPIDVKFGYLGELTLLI 68
LL R+LG YV L + +W GDV L++L+L+ ++L++L LP+ VK G++G +TL +
Sbjct: 11 LLRRYLGEYVHGLSTEALRISVWKGDVVLKDLKLKAEALNSLKLPVAVKSGFVGTITLKV 70
Query: 69 PWSSLKNKPVKIIIEDVYMLCAPR-------------TPESYNVEEQIERELKV-KLQRL 114
PW SL +PV ++I+ V++L P T +Y R+ K + Q
Sbjct: 71 PWKSLGKEPVIVLIDRVFVLAYPAPDDRTLKFFTLVGTEFAYTNYIPGGRQGKASRNQAS 130
Query: 115 AD--------FELANSSKPDINLDSN---------RNESFTQSLLTKIVDNLQVTVKNIH 157
AD EL L++ + S+ S++ I+ NL+V++ N+H
Sbjct: 131 ADRGTSYFWLMELHGYEAETATLEARAKSKLGSPPQGNSWLGSIIATIIGNLKVSISNVH 190
Query: 158 MRYED---------------MNSVFSEG---PCAFGISLSELSAVSTDESWNPSF-ISIK 198
+RYED N++ S P A GI+L++L+AV+ DE N +F S
Sbjct: 191 IRYEDSTRDSSEILASFFSYFNNICSSNPGHPFAAGITLAKLAAVTMDEEGNETFDTSGA 250
Query: 199 QQITHKLATLDSISIYCNTGTESIETDDS------EELLIRLRESIAD-------NRGAP 245
K L+ +++Y ++ + E + EE + + I + ++ A
Sbjct: 251 LDKLRKSLQLERLALYHDSNSFPWEIEKQWDNITPEEWIEMFEDGIKEQTEHKIKSKWAL 310
Query: 246 EYQYLLKPVRGSARLKMNKAGATE----DAPHIDVQLMFDEFALVLDDCQYKEVLHNLSK 301
YLL P+ GS LK ++ G E + P ++ ++ + + + QY + + +
Sbjct: 311 NRHYLLSPINGS--LKYHRLGNQERNNPEIPFERASVILNDVNVTITEEQYHDWIKLVEV 368
Query: 302 YHWFHKTLKYRQHRPTVKPAADPALWFKYAANCVLSEIHEKNYKSSWEYIKERRNKRDEY 361
+ ++ RP V + P LW+++AA L +++R Y
Sbjct: 369 VSRYKTYIEISHLRPMVPVSEAPRLWWRFAAQASL---------------QQKRLWYTRY 413
Query: 362 VSLFKKKL-TLPDINDPLPNVEEEKRLHALDVELSFDDIKFFRAFTRREFCQESKFTQLS 420
+ L+ L D+N P + ++ +L I +R + + K + +
Sbjct: 414 IQLYANFLQQSSDVNYP--------EMREIEKDLDSKVILLWRLLAHAK-VESVKSKEAA 464
Query: 421 ETISTNANPQGWFSSWWAPS-------NAKSDDSLTMTDEQRKELYDAIEYDDSNDPLKS 473
E GWFS W ++ + S M + K+ + AI S+ P +
Sbjct: 465 E--QRKLKKGGWFSFNWRTEAEDDPEVDSVAGGSKLMEERLTKDEWKAINKLLSHQPDEE 522
Query: 474 VDI-----PKDRTTLRVTNLLQKGSLTVMDRTKGHRMCD-FIFEESATEFLNRPDXXXXX 527
+++ ++ T VT + +G+ ++D + +C F + T+F +R
Sbjct: 523 MNLYSGKDMQNMTHFLVTVSIGQGAARIVDINQTEVLCGRFEQLDVTTKFRHRSTQCDVS 582
Query: 528 XXXXXXXVEDGSPHTLYRHIVSPRTKHEKGGDPLLHLYFDSCPMDESADTFLDIKFGSVF 587
+GS L + + S R + L F + P+ E+ D L
Sbjct: 583 LRFYGLSAPEGS---LAQSVSSERKTN------ALMASFVNAPIGENIDWRLSATISPCH 633
Query: 588 VYYHIHFINELIRFFN-----PPTKHWETVSALMNAAEATVEGWTSQTRMGLEALLNEHK 642
+ ++ F PT ET + L + +E T + + L+ +L E
Sbjct: 634 ATIWTESYDRVLEFVKRSNAVSPTVALETAAVL----QMKLEEVTRRAQEQLQIVLEEQS 689
Query: 643 TIDLKLNAASPTIIIPLDAHSWESPCA---IIDAGSIKMSSDLVPKQEIKKIKELSVDEY 699
L ++ +P + IPL A S S C+ ++D G+ +++
Sbjct: 690 RFALDIDIDAPKVRIPLRA-SGSSKCSSHFLLDFGNFTLTT------------------- 729
Query: 700 AKIDSDELKRLMFDRFKIKLTD--------------TQLLIGPDMKSSITSINVKQRDNN 745
S+E ++ ++ RF I D L++ I S +++ DN
Sbjct: 730 MDTRSEEQRQNLYSRFCISGRDIAAFFTDCGSDNQGCSLVMEDFTNQPILSPILEKADNV 789
Query: 746 FTILEKMELDFILDILIFPKALNLPRVAASVTLPSLNIFLNDFQYKIIMQLVE 798
++++++ + I+D + P + P S+ +P++ + + +Y IMQL +
Sbjct: 790 YSLIDRCGMAVIVDQIKVPHP-SYPSTRISIQVPNIGVHFSPTRYMRIMQLFD 841
Score = 67.0 bits (162), Expect = 5e-10
Identities = 80/352 (22%), Positives = 133/352 (37%), Gaps = 74/352 (21%)
Query: 2730 LQPTLLHLSFVRTDRVNVEEEKSSGNSAINYFINVLTMALGNIEGAQIKLNSLLLEHVRV 2789
+Q +L+ S VR RV++ S + F + L ALGN E ++++ E++ +
Sbjct: 3685 IQIGVLNFSEVRF-RVSMAMSPSQRPRGVLGFWSSLMTALGNTENMPVRISERFHENISM 3743
Query: 2790 SLPTLVGAIESHYAQQFFYQLHKVLGSADFLGNPVGFFNNISSGVMDIFYEPYQGYIMND 2849
T++ + + Q ++L D LGN ++S G+ + + + +I +
Sbjct: 3744 RQSTMINNAIRNVKKDLLGQPLQLLSGVDILGNASSALGHMSQGIAALSMD--KKFIQSR 3801
Query: 2850 RPQELGIGIAKGGLSFLKKSIFGFSDSFSKMTGSMAKGLSVAIQDTSFXXXXXXXXXXXG 2909
+ QE K + F D + G++AKGL +
Sbjct: 3802 QRQE-------------NKGVEDFGDIIREGGGALAKGLFRGV----------TGILTKP 3838
Query: 2910 KFGSVGVGASSFFNNVTSGLTGVALDPYSGGAKEXXXXXXXXXXXXXXXLPAKTAIGVLD 2969
G+ G F + G+ G A P SG VLD
Sbjct: 3839 LEGAKSSGVEGFVSGFGKGIIGAAAQPVSG---------------------------VLD 3871
Query: 2970 LASNVSEG-----IRNSTTLMDIGQIERVRLPRFVSSDKLIKPYNLRDSQGQYWLKTCNG 3024
L S +EG ++ + + Q+ R RLPR V +D L++PYN +QGQ L+
Sbjct: 3872 LLSKTTEGANAMRMKIAAAITSDEQLLRRRLPRAVGADSLLRPYNDYRAQGQVILQLAES 3931
Query: 3025 GEY--------------AKDMYVGHVICETPAGYQIVIVSLQRILRMQLSTL 3062
G + D Y H I P G ++I + IL Q S +
Sbjct: 3932 GSFLGQVDLFKVRGKFALTDAYESHFI--LPKGKVLMITHRRVILLQQPSNI 3981
>Hs8923139 [U] KOG1809 Vacuolar protein sorting-associated protein
Length = 442
Score = 125 bits (315), Expect = 8e-28
Identities = 77/297 (25%), Positives = 139/297 (45%), Gaps = 9/297 (3%)
Query: 2724 YFEMLHLQPTLLHLSFVRT---DRVNVEEEKSSGNSAINYFINVLTMALGNIEGAQIKLN 2780
+FE H+ P LHLS + + E+++ ++N + + L +++ KL
Sbjct: 13 FFEHFHISPVKLHLSLSLGSGGEESDKEKQEMFAVHSVNLLLKSIGATLTDVDDLIFKLA 72
Query: 2781 SLLLEHVRVSLPTLVGAIESHYAQQFFYQLHKVLGSADFLGNPVGFFNNISSGVMDIFYE 2840
+ + L+ ++ HY++QF Q++ ++ D LGNP G +S GV +FYE
Sbjct: 73 YYEIRYQFYKRDQLIWSVVRHYSEQFLKQMYVLVLGLDVLGNPFGLIRGLSEGVEALFYE 132
Query: 2841 PYQGYIMNDRPQELGIGIAKGGLSFLKKSIFGFSDSFSKMTGSMAKGLSVAIQDTSFXXX 2900
P+QG + P+E G+ G S ++ G + S++TGS+ KGL+ D +
Sbjct: 133 PFQGAVQG--PEEFAEGLVIGVRSLFGHTVGGAAGVVSRITGSVGKGLAAITMDKEYQQK 190
Query: 2901 XXXXXXXXGK-FG-SVGVGASSFFNNVTSGLTGVALDPYSGGAKEXXXXXXXXXXXXXXX 2958
+ FG S+ G F V G+TG+ P G KE
Sbjct: 191 RREELSRQPRDFGDSLARGGKGFLRGVVGGVTGIITKPVEGAKKEGAAGFFKGIGKGLVG 250
Query: 2959 LPAKTAIGVLDLASNVSEGIRNSTTLMDIGQIERVRLPRFVSSDKLIKPYNLRDSQG 3015
A+ G++D+AS+ +GI+ + + ++ +R PR + D +I+PY+ ++S+G
Sbjct: 251 AVARPTGGIVDMASSTFQGIQRAAESTE--EVSSLRPPRLIHEDGIIRPYDRQESEG 305
>Hs22041525 [U] KOG1796 Vacuolar protein sorting-associated protein
Length = 1231
Score = 100 bits (249), Expect = 4e-20
Identities = 100/443 (22%), Positives = 176/443 (39%), Gaps = 43/443 (9%)
Query: 2579 QELCYINILGLEFRFNDSEMYQNLSFKMKWIQIDNQLFGGVYETVLYPTKIPKDSKEIDI 2638
+EL + ++ G+ + L ++ +Q+DNQL G +LY T + +++ I+
Sbjct: 690 EELVFASLTGINVHYTQLATSHMLELSIQDVQVDNQLIGTTQPFMLYVTPLSNENEVIET 749
Query: 2639 HPSLSGAISKVKDESSSLLN--FKMATLLLQEMTIQIDEXXXXXXXXXXKIPGASWNQAV 2696
P++ ++ VK S S L +K + Q T+QI+E ++QA
Sbjct: 750 GPAVQ--VNAVKFPSKSALTNIYKHLMITAQRFTVQIEEKLLLKLLSFF-----GYDQAE 802
Query: 2697 DDSSSEQLFLHPCTVPDFPTTVRSSKVYFEMLHLQPTLLHLSFVRTDRVNVEEEKSSGNS 2756
+ LH T T +R YFE L + + LS ++++ ++
Sbjct: 803 SEVEKYDENLHEKTAEQGGTPIR---YYFENLKISIPQIKLSVFTSNKLPLD-------- 851
Query: 2757 AINYFINVLTMALGNIEGAQIKLNSLLLEHVRVSLPTLVGAIESHYAQQFFYQLHKVLGS 2816
+ + L L E A I L+ H + ++ I H+ ++ Q ++LGS
Sbjct: 852 -LKALKSTLGFPLIRFEDAVINLDPFTRVHPYETKEFIINDILKHFQEELLSQAARILGS 910
Query: 2817 ADFLGNPVGFFNNISSGVMDIFYEPYQGYIMNDRPQELGIGIAKGGLSFLKKSIFGFSDS 2876
DFLGNP+G N++S GV + G + GGL ++ G S+S
Sbjct: 911 VDFLGNPMGLLNDVSEGVTGLI---KYGNV--------------GGL--IRNVTHGVSNS 951
Query: 2877 FSKMTGSMAKGLSVAIQDTSFXXXXXXXXXXXGKFGSVGVGASSFFNNVTSGLTGVALDP 2936
+K G+++ GL + + + G + + GLT V
Sbjct: 952 AAKFAGTLSDGLGKTMDNRHQSEREYIRYHAATSGEHLVAGIHGLAHGIIGGLTSVITST 1011
Query: 2937 YSGGAKE-XXXXXXXXXXXXXXXLPAKTAIGVLDLASNVSEGIRNSTTLM-DIGQIERVR 2994
G E K G LD AS ++ +R++ TL Q +RVR
Sbjct: 1012 VEGVKTEGGVSGFISGLGKGLVGTVTKPVAGALDFASETAQAVRDTATLSGPRTQAQRVR 1071
Query: 2995 LPRFVSSDK-LIKPYNLRDSQGQ 3016
PR + + L+ Y+ ++GQ
Sbjct: 1072 KPRCCTGPQGLLPRYSESQAEGQ 1094
Score = 69.3 bits (168), Expect = 9e-11
Identities = 92/371 (24%), Positives = 154/371 (40%), Gaps = 36/371 (9%)
Query: 2062 PRMTVTLSAPLVLENSLPQDISFCLKGRKEEARSEIFLQAGATIPLHNVSLDSYLLLSIK 2121
P T+ L +V+ N LP ++ F +KG L+ G LH + L +
Sbjct: 17 PGHTIYLLPTVVICNLLPCELDFYVKGMPINGT----LKPGKEAALHTADTSQNIELGVS 72
Query: 2122 PDDENFNWSNETLVNSPDVSALEEEHRIFITTLDGQKLYLSLKYHANGKRAKTISIYAPY 2181
ENF E L+ P R++ ++ ++L L+++ + + I I APY
Sbjct: 73 L--ENFPLCKELLI-PPGTQNYMVRMRLY--DVNRRQLNLTIRIVCRAEGSLKIFISAPY 127
Query: 2182 VIMNKTTHDLSVFSDRQWGVVKSDVFMK-DGQKLAR---PKMFSF-QYEDYNRNRAKIK- 2235
++NKT L D K+D + + +LAR P +F + E N +I
Sbjct: 128 WLINKTGLPLIFRQDN----AKTDAAGQFEEHELARSLSPLLFCYADKEQPNLCTMRIGR 183
Query: 2236 --FTETNPSVPVSFDAIGQSVDISLELLNHNQE----CNLGINVKEGEGKYRFTKIVEIS 2289
E P F G S +L+++ N+GI+VK+G G+Y T +V +
Sbjct: 184 GIHPEGMPGWCQGFSLDGGSGVRALKVIQQGNRPGLIYNIGIDVKKGRGRYIDTCMVIFA 243
Query: 2290 PRYIFRNSTSEVIEIME------YGTSSP---TILAPKELTPLYFLKRTLSKKFVARFAK 2340
PRY+ N +S + + GT++P P ++ + + R
Sbjct: 244 PRYLLDNKSSHKLAFAQREFARGQGTANPEGYISTLPGSSVVFHWPRNDYDQLLCVRLMD 303
Query: 2341 IPS-TWSNPFRLKDVGESFVKMNITDAAQRLIKMDISLEGATVFINAVDSDD-NWPFSIR 2398
+P+ WS F + + M T ++++I+L GAT I+ D+D PF I
Sbjct: 304 VPNCIWSGGFEVNKNNSFHINMRDTLGKCFFLRVEITLRGATYRISFSDTDQLPPPFRID 363
Query: 2399 NFSDHEFLFWQ 2409
NFS +F Q
Sbjct: 364 NFSKVPVVFTQ 374
>7301869 [U] KOG1809 Vacuolar protein sorting-associated protein
Length = 2757
Score = 92.8 bits (229), Expect = 8e-18
Identities = 58/215 (26%), Positives = 112/215 (51%), Gaps = 18/215 (8%)
Query: 2 LESLVSALLNRFLGAYVENFDPTQLNVGIWNGDVKLRNLRLRKDSLDA-LDLPIDVKFGY 60
LES ++ +L ++ YV+NF V +W G+V +NL LR + L+ L+LP+++ G+
Sbjct: 4 LESYITPILLSYVAKYVKNFRDEDAQVSLWEGEVTFQNLDLRLEVLEEELNLPVELVSGH 63
Query: 61 LGELTLLIPWSSLKNKPVKIIIEDVYMLCAPRTPESYNVEEQIERELKVKLQRLADFELA 120
+ EL++L+PW+ L ++PVKI+I + + ES +RE + K +R
Sbjct: 64 IHELSILVPWTKLMSEPVKIVINTIEFVAKLPDSESKQRRASFQREQRRKSKR------E 117
Query: 121 NSSKPDINLDSNRNESFTQSLLTKIVDNLQVTVKNIHMRYEDMNSVFSEGPCAFGISLSE 180
+ +PD + + + S++ KI++N+ + NI ++Y + + V S +++
Sbjct: 118 SVEQPD--QTKSPGPASSSSVVNKIINNINLQCHNIILKYVEDDIVVS-------MNVQT 168
Query: 181 LSAVSTDESWNPSFISIK--QQITHKLATLDSISI 213
L+ S E W P+ + I + KL + ++I
Sbjct: 169 LNFSSAGEDWKPTMVDIHPVSVVMRKLLQVSDLTI 203
>CE02506 [U] KOG1796 Vacuolar protein sorting-associated protein
Length = 2102
Score = 85.5 bits (210), Expect = 1e-15
Identities = 144/702 (20%), Positives = 286/702 (40%), Gaps = 71/702 (10%)
Query: 1757 VISTIEPFASAFNYSRSSWEPLIEVFPMT--FHLSKDDENDNALIFDIITRKSVEIT--L 1812
+I++ FN WEP+IE + + H KD + + + + ++ +T L
Sbjct: 692 IIASFHVSMDYFNQRIFGWEPVIEEWKILRFLHNKKDLKQTIEWVAETKSTLNINVTEQL 751
Query: 1813 SSRTIALLSQIPASLT-------KSHNLKPRGAEKPYRIHNDTGHTLNIWIKNSDDDAVN 1865
++I +++PA L ++ + PY + N TG + + +D +
Sbjct: 752 IQQSIQWNTKLPAILASFERDDFRNQCTRSSSDHLPYVMKNTTG--CEVHFTTAVEDVLT 809
Query: 1866 KRANLTKLQS-------GEIIDWEFEDWRVVRETLDTE---KCMLRASFADDDYSNIIDV 1915
R+ K + G+ ++EF ++ L+ E + ++R S D+ I V
Sbjct: 810 ARSEQRKSTTRWMTVGRGQEKNFEFPARLLLYSHLEREPPRQLIVRVSGWDE----ISPV 865
Query: 1916 DASKEGD---VIHKLYPPVAGVHNRLLISSNLLENNVKLITFGSTLLLRNLTSTEVEYGL 1972
+ G VI L P + RLLIS + + K++T S++ + N +
Sbjct: 866 NVDSCGTYFRVIKALRPQLKNA--RLLISVTMENDGKKVVTLKSSIDITNHLPHPIAVQ- 922
Query: 1973 SDAGKIKSIGVINPNGTRSIPIDSAY--QSSFHIRPLT--DNASYKWSGIPIFWKMLSES 2028
++ K + + PNG S+P++ A+ +++ + P+ ++A W + I ++ +++
Sbjct: 923 TEGTKGGEVMSVEPNGVVSVPLEFAHCTLTAYPVGPMPVIEHAELSWKSVRISGEVCNQT 982
Query: 2029 PLALSCESDLETAGFHFEVEGSVDKDDPLSKI--YPRMTVTLSAPLVLENSLPQDISFCL 2086
L SD F++ + P P ++ L APL L+N LP D+
Sbjct: 983 Q-RLKTRSDSNLNRFYWVCTAIRREYYPEHDFESLPGHSIHLVAPLSLQNLLPIDVEI-- 1039
Query: 2087 KGRKEEARSEIFLQAGATIPLHNVSLDSYLLLSIKPDDENFNWSNETLVNSPDVSALEEE 2146
+ + +F A A+ + S+D LSI + L+N +++ E
Sbjct: 1040 -----KIQDNVFAIA-ASKSMLITSVDITKELSITVSTDRLQSQAPLLINK---ASIGEG 1090
Query: 2147 HRIFITTLDGQKLYLSLKYHA--NGKRAKTISIYAPYVIMNKTTHDLSVFSDRQWGVVKS 2204
+F D + L + H +A ++S++ PY I+NK+ L + +
Sbjct: 1091 TLLFTKMADSKGHLLDMYCHVRLGVAQAISVSLWVPYWIVNKSGIPLIIQQEAVKWEAAG 1150
Query: 2205 DVFMKDGQKLARPKMFSFQYEDYNR------NRAKIKFTETNPSVPVSFDAIGQSVDISL 2258
+ + K P MFSF E+ + A I+ + F + L
Sbjct: 1151 QMEEHEKAKDRHPLMFSFADENCPKACRVRVGNAYIRENGYRSILSEKFTLTPGVQALKL 1210
Query: 2259 ELLNHNQEC---NLGINVKEGEGKYRFTKIVEISPRYIFRNSTSEVI-----EIMEYGTS 2310
+ + + NLG+ V+ G G+Y+ T++V ++ R++ +N ++ + +++E
Sbjct: 1211 RVEHKTKPTFYYNLGVEVRPGTGRYKDTQVVLLTSRFLLQNQSTVALSVCHHDLVEMEKD 1270
Query: 2311 SPTILAPKELTPLYFLKRTLSKKFVARFAKIPSTWSNPFRLKDVGESFVKMNITDAAQRL 2370
+ A T + + ++ + WS PF + +G V M D R
Sbjct: 1271 HVHLAAQSSTT---WNENYAGRRMLCVRRADVKHWSCPFLIDRIGSFHVTMRDADETPRF 1327
Query: 2371 IKMDISLEGATVFINAVDSD-DNWPFSIRNFSDHEFLFWQRN 2411
I+++I L A I ++D P I N +D L+ Q +
Sbjct: 1328 IRVEIILTSAVFQITFTNADLYPPPIRIENLTDVPVLYQQES 1369
>Hs8923545 [U] KOG1809 Vacuolar protein sorting-associated protein
Length = 412
Score = 80.1 bits (196), Expect = 5e-14
Identities = 53/203 (26%), Positives = 99/203 (48%), Gaps = 17/203 (8%)
Query: 1 MLESLVSALLNRFLGAYVENFDPTQLNVGIWNGDVKLRNLRLRKDSLD-ALDLPIDVKFG 59
MLES V+ +L ++ Y++N P+ L + +W GDV L L L+ D L+ L LP G
Sbjct: 1 MLESYVTPILMSYVNRYIKNLKPSDLQLSLWGGDVVLSKLELKLDVLEQELKLPFTFLSG 60
Query: 60 YLGELTLLIPWSSLKNKPVKIIIEDVYMLCAPRTPESYNVEEQIERELKVKLQRLADFEL 119
++ EL + +PW+ L ++PV I I M C + + +++ E R
Sbjct: 61 HIHELRIHVPWTKLGSEPVVITINT--MECILKLKD--GIQDDHESCGSNSTNRSTAEST 116
Query: 120 ANSSKP-----DINLDSNRNESFTQSLLTKIVDNLQVTVKNIHMRYEDMNSVFSEGPCAF 174
+S KP D + + QSL+ ++V+N+ + + N+ ++Y + + V S
Sbjct: 117 KSSIKPRRMQQAAPTDPDLPPGYVQSLIRRVVNNVNIVINNLILKYVEDDIVLS------ 170
Query: 175 GISLSELSAVSTDESWNPSFISI 197
++++ + E W+ +F+ I
Sbjct: 171 -VNITSAECYTVGELWDRAFMDI 192
>7294545 [U] KOG1796 Vacuolar protein sorting-associated protein
Length = 1902
Score = 78.6 bits (192), Expect = 2e-13
Identities = 88/402 (21%), Positives = 151/402 (36%), Gaps = 40/402 (9%)
Query: 2579 QELCYINILGLEFRFNDSEMYQNLSFKMKWIQIDNQLFGGVYETVLYPTKIPKDSKEIDI 2638
+E+ +I++ + S + +L + +IQIDNQL V L+ T+ D +E
Sbjct: 1474 EEIMFISLDHINCDIVQSALENSLDLNIAYIQIDNQLLDAVSPIALH-TQTSNDLEETQN 1532
Query: 2639 HPSLSGAISKVKDESSSLLNFKMATLLLQEMTIQIDEXXXXXXXXXXKIPGASWNQAVDD 2698
L + + + + + FK TL L+ T ++E + +
Sbjct: 1533 AVVLK--LKMLPSPNKNAIIFKYLTLDLKPSTASLEEKLILKVASFL-----GYGKINRQ 1585
Query: 2699 SSSEQLFLHPCTVPDFPTTVRSSKVYFEMLHLQPTLLHLSFVRTDRVNVEEEKSSGNSAI 2758
+ S Q D P + YFE L + T + LS + ++ VE ++
Sbjct: 1586 NLSVQYQFE--NTDDKPFLQDMKRYYFENLSIGATQVRLSAFTSSKLPVELHETK----- 1638
Query: 2759 NYFINVLTMALGNIEGAQIKLNSLLLEHVRVSLPTLVGAIESHYAQQFFYQLHKVLGSAD 2818
L + L E A I+L+ + ++ ++ HY Q + +LGS D
Sbjct: 1639 ----KALGLTLIKFEDALIELDRYSDKLHFETMDVYRKELKKHYINQVKWHAAAILGSVD 1694
Query: 2819 FLGNPVGFFNNISSGVMDIFYEPYQGYIMNDRPQELGIGIAKGGLSFLKKSIFGFSDSFS 2878
FLGNP+GF N++S GV + +E G K S +K G S+S +
Sbjct: 1695 FLGNPLGFANDLSEGVSGLIFE----------------GSVK---SLVKNVTHGISNSTA 1735
Query: 2879 KMTGSMAKGLSVAIQD--TSFXXXXXXXXXXXGKFGSVGVGASSFFNNVTSGLTGVALDP 2936
K+T +++ L + D + G + G + G+T +
Sbjct: 1736 KLTETLSDSLGKVVLDDHDNETRQRILELQSNTSGGHLAAGLKGLGFGLLGGVTSIVRHT 1795
Query: 2937 YSGGAKEXXXXXXXXXXXXXXXLPAKTAIGVLDLASNVSEGI 2978
Y G + K IGVLDLAS + +
Sbjct: 1796 YDGATSDGVPGFLSGLGKGLVGTVTKPIIGVLDLASETASAV 1837
Score = 72.0 bits (175), Expect = 1e-11
Identities = 194/943 (20%), Positives = 360/943 (37%), Gaps = 127/943 (13%)
Query: 1501 SYSKEELPNEAL---PDDLAVASKVENSNKTFNYSVNVVDSAVILLADPSDKQSEAIVFT 1557
SY +E+ P + + +A +++ S T Y VN+ DS +I + S S AI+
Sbjct: 277 SYLQEDSPAPVVNNAANQIAQKPQIDTSIST-EYVVNITDSEIIFAEECSRLDSNAIILK 335
Query: 1558 IGQFLVTDHNI----LSIAANNVGLFLSRMGDLNQNRIRILDDFSSTVMIDGRDSTPDIL 1613
+ N LS+ N++ +F + ++ + I+D F T++I+ R + +IL
Sbjct: 336 STTVICYKPNSNIVPLSLDINHLEIFSCTLDAEEESALSIIDPF--TLIIELRSNCLNIL 393
Query: 1614 KTQIHSSVGPXXXXXXXXXXXXAMEIFNSSLSLAKDEGLMIVXXXXXXXXXXXXKYGKFS 1673
Q H ++ +++F+ L + +
Sbjct: 394 -IQKHLNI---------RLSYVDVKLFSRMARLLPTQ---------------TSRPKNVI 428
Query: 1674 REFKNKIKKYAPSMVSSLSEISNVMHRNSISD----STKVITKAEKLHS----------- 1718
+ + ++K AP +V+ EIS+ ++ I++ + +K ++
Sbjct: 429 SKADSDLEKAAP-LVAMGFEISDCLYAMQINNWRINDAAIWLSQQKQNTYRNPALEMKTA 487
Query: 1719 --DFAGLRVVLIGDMHE--LPIADFNINAFSV-------DAKDWSTNIDVIS--TIEPFA 1765
D + + V +I D + +P+ + +++ F + D TNI S I+
Sbjct: 488 VVDASLISVFIIDDCMDADVPLLEVSLSKFLLNFTFQTQDPNPKETNIRHYSLGNIDTEV 547
Query: 1766 SAFNYSR--SSWEPLIEVFPMTFHLSKDDEN-DNALIFDI--ITRKSVEITLSSRTIALL 1820
S Y+R S WEP+ E + + + DN F+I +++ +++ ++S I L
Sbjct: 548 SVNYYNRRLSGWEPVAETWESNLNWKYTKGHLDNKKRFEIGISSKQMLKLNVTSTFIELF 607
Query: 1821 SQIPASLTK------SHNLKPRGAEKPYRIHNDTGHTLNIW--------IKNSDDDAVNK 1866
+ + T + N + R P+ + N +G L + SD V
Sbjct: 608 HMVLKNWTNDFNDNGAKNFRQRSPFIPFALQNLSGTPLLFKPIYAPLGDLTRSDLQQVEL 667
Query: 1867 RANLTKLQSGEIIDWEFEDWRVVRETLDTEKCMLRASFADDDYSNIIDVDASKEGDVIH- 1925
N +Q E ++F +R + + + ++ I + K G
Sbjct: 668 IKNWYSVQPNETKTFDFSQKSKLRHVHSHQLNLHQIFVQIHGWTLIGPISVDKVGMFFRT 727
Query: 1926 -KLYPPVAGVHNRLLISSNLLENNVKLITFGSTLLLRNLTSTEVEYGLSDAGK----IKS 1980
KL +R++ +L+ + KLI S+L + N V ++ G + S
Sbjct: 728 TKLDSQFL-TKSRIVFDISLIGSAQKLIKVKSSLGVINKLDRNVFLKMTLKGTHSDGLSS 786
Query: 1981 IGVINPNGTRSIPIDSAYQSSFHIRPLTDNASYKWSGIP---IFWKMLSESPLA-LSCES 2036
I VI PN S+P+ S + +++ +Y+ +G I WK + L
Sbjct: 787 ISVIKPNDELSVPLKFIDASLYVAHNTSESDAYEDTGFSNEEILWKACGKDDTRQLLAGY 846
Query: 2037 DLETAGFHFEVEGSVDKDDPLSKIYPRMTVTLSAPLVLENSLPQDISFCLKGRKEEARSE 2096
D + + V S + + P +TL PL + N L D+ F + E A
Sbjct: 847 DTNKSILYTFVNISREIYHCKEQNLPGHKITLLPPLKINNMLCCDLMFKIH---EHATGR 903
Query: 2097 IFLQAGATIPLHNVSLDSYLLLSIKPDDENFNWSNETLVNSPDVSALEEEHRIFITTLDG 2156
I + ++ ++NV++ L LSI D NF S + + +E + ++ +D
Sbjct: 904 I--NSSESVNIYNVNICQPLNLSITLD--NFQLSGQLKIPVSHRGVIEPKLKL----IDI 955
Query: 2157 QKLYLSLKYHANGKRAKTISIY--APYVIMNKTTHDLSVFSDRQWGVVKSDVFMKDGQKL 2214
QK L ++ K + +Y AP I+NKT L + + +
Sbjct: 956 QKRELHVRVSIQSVPGKGMELYISAPVWIINKTGLPLIYKQEGTSHTAAGQFEEHETARQ 1015
Query: 2215 ARPKMFSFQYEDYNRNRAKI----KFTETNPSVPVSFDAIGQSVDISLELLNHNQECNLG 2270
P MFSF D + A + K +N SF D L N +G
Sbjct: 1016 VAPLMFSFS--DQEGSPALVLRLGKAYGSNNMWCKSFSTHKDLADRDLRAENTKGSYAIG 1073
Query: 2271 INVKEGEGKYRFTKIVEISPRYIFRNSTSEVIEIME------YGTSSP--TILAPKELTP 2322
I+V+ G G Y T V +SPR+ N + +E M+ Y P I AP +
Sbjct: 1074 ISVRRGRGLYACTTFVTLSPRFHLHNRSGYKLEFMQLCDIVNYDRPDPRKIISAPVDCNF 1133
Query: 2323 LYFLKRTLSKKFVARFAKIPS----TWSNPFRLKDVGESFVKM 2361
+ ++ + +IP WS +KDV ++ +
Sbjct: 1134 AFHWPNWDQEQIIC--VRIPEIECCCWSKGIPIKDVQSLYINL 1174
>ECU04g0690 [U] KOG1809 Vacuolar protein sorting-associated protein
Length = 2371
Score = 77.8 bits (190), Expect = 3e-13
Identities = 75/311 (24%), Positives = 127/311 (40%), Gaps = 34/311 (10%)
Query: 2709 CTVPDFPTTVRSSKV-----YFEMLHLQPTLLHLSFVRTDRVNVEEEKSSGNSA----IN 2759
C V DF + S FE+ P H +R + +E ++ N +
Sbjct: 1965 CRVQDFALNIEESLAKKVSKMFEVKEHAPRG-HGRNIRIQNLKMERLRAKVNFLKDVESD 2023
Query: 2760 YFINVLTMALGNIEGAQIKLNSLLLEHVRVSLPTLVGAIESHYAQQFFYQLHKVLGSADF 2819
+ +V + NI ++++ + + + L + S Y QF L+KVL D
Sbjct: 2024 FISSVTGFLINNISDFSLEMDGMKESCLYTTAEELRSLLASFYLSQFRRNLYKVLTHFDL 2083
Query: 2820 LGNPVGFFNNISSGVMDIFYEPYQGYIMNDRPQELGIGIAKGGLSFLKKSIFGFSDSFSK 2879
+GN F ++S G+ D+F EP + GIAKGG SFLK +I+G S++ K
Sbjct: 2084 IGNIGSFTESVSVGIKDLFVEPTLS------RTNVARGIAKGGKSFLKNTIYGVSNTVGK 2137
Query: 2880 M-----TGSMAKGLSVAIQDTSFXXXXX--------XXXXXXGKFGSVGVGASSFFNNVT 2926
TG+ G ++ ++ G S+ G F+++T
Sbjct: 2138 FSKSIGTGARLVGCNIELRHAKGHHSYACDVHLLVPRSKHSKGSVVSILRGTGDLFDSIT 2197
Query: 2927 SGLTGVALDPYSGGAKEXXXXXXXXXXXXXXXLPAKTAIGVLDLASNVSEGIRNSTTLMD 2986
G+ G+A P GA + + + V DL + +S+ I+ S MD
Sbjct: 2198 RGIAGIATSPIE-GASQGVTGVVKGLGKGILGAFTRPIVEVADLVTGISDTIKVS---MD 2253
Query: 2987 IGQIERVRLPR 2997
G+I+R++ PR
Sbjct: 2254 -GRIKRLQYPR 2263
Score = 69.3 bits (168), Expect = 9e-11
Identities = 38/85 (44%), Positives = 51/85 (59%), Gaps = 1/85 (1%)
Query: 1 MLESLVSALLNRFLGAYVENFDPTQLNVGIWNGDVKLRNLRLRKDSLDALDLPIDVKFGY 60
ML+ ++ LNRFLG YVEN D QL +GI+ G V + NLR++ + L V
Sbjct: 1 MLKRILLKTLNRFLGNYVENIDKHQLELGIFKGYVSVSNLRIKSSVISRL-FDGRVVSNR 59
Query: 61 LGELTLLIPWSSLKNKPVKIIIEDV 85
+G L +L+PW SL KPV+I I DV
Sbjct: 60 IGTLRVLVPWKSLARKPVEIYIRDV 84
>Hs22048785 [U] KOG1809 Vacuolar protein sorting-associated protein
Length = 1687
Score = 54.7 bits (130), Expect = 2e-06
Identities = 31/95 (32%), Positives = 49/95 (50%), Gaps = 2/95 (2%)
Query: 2794 LVGAIESHYAQQFFYQLHKVLGSADFLGNPVGFFNNISSGVMDIFYEPYQGYIMNDRPQE 2853
LV A+ HYA ++ V+GS D LG+P +I +GV D F PY+G + P
Sbjct: 1296 LVHALAMHYAAGALFRAGWVVGSLDILGSPASLVRSIGNGVADFFRLPYEG--LTRGPGA 1353
Query: 2854 LGIGIAKGGLSFLKKSIFGFSDSFSKMTGSMAKGL 2888
G+++G SF+K G S + + S+A+ +
Sbjct: 1354 FVSGVSRGTTSFVKHISKGTLTSITNLATSLARNM 1388
>CE04771 [U] KOG2993 Cytoplasm to vacuole targeting protein
Length = 2247
Score = 54.3 bits (129), Expect = 3e-06
Identities = 33/129 (25%), Positives = 69/129 (52%), Gaps = 5/129 (3%)
Query: 9 LLNRFLGAYVEN-FDPTQLNVGIWNGDVKLRNLRLRKDSLD----ALDLPIDVKFGYLGE 63
+L R++GA+++N QL++ + NG ++L NL + ++ ++P+ + GYLG+
Sbjct: 14 MLQRYMGAWLDNNLSVDQLSLELANGCLELDNLDINTKAVSNGFLQCNIPLKLIDGYLGK 73
Query: 64 LTLLIPWSSLKNKPVKIIIEDVYMLCAPRTPESYNVEEQIERELKVKLQRLADFELANSS 123
+ + IPW SL P ++ IED+ + N E + ++ L L+ ++A S
Sbjct: 74 IKIEIPWLSLMTDPTRMCIEDLQLTFRGAEVMKINDIETLTSMIESVLMGLSTDDMARSV 133
Query: 124 KPDINLDSN 132
+++ ++N
Sbjct: 134 YEEVSKENN 142
>CE28285 [S] KOG2955 Uncharacterized conserved protein
Length = 745
Score = 52.8 bits (125), Expect = 9e-06
Identities = 39/192 (20%), Positives = 87/192 (45%), Gaps = 36/192 (18%)
Query: 2 LESLVSALLNRFLGAYVENFDPTQLNVGIWNGDVKLRNLRLRKDSL-DALDLP--IDVKF 58
+ S++ L + L + +N P Q+++ + G+ KL+ + + +D L + L+LP + +K
Sbjct: 1 MTSIIKNQLVKHLSKFTKNLKPEQISLDVLKGNSKLQFIEINEDVLTEILELPSWLKIKR 60
Query: 59 GYLGELTLLIPWSSLKNKPVKIIIEDVYMLCAPRTPESYNVEEQIERELKVKLQRLADFE 118
+ + + +PW+ LK P++I I+++ NV+ ++ E K + +
Sbjct: 61 AFCTGVAVNVPWTKLKTCPIQIFIDEI------------NVDVELTNEHKKQAKS----- 103
Query: 119 LANSSKPDINLDSNRNESFTQSLLTKIVDNLQVTVKNIHMRYEDMNSVFSEGPCAFGISL 178
N N +S + + KI++N+ + + ++ + ++ + VF L
Sbjct: 104 ---------NPLGNLGDSSSYGFMNKIIENMSLYISSVEINFD--SDVFGG-----SFML 147
Query: 179 SELSAVSTDESW 190
LS S W
Sbjct: 148 QRLSVESRSPGW 159
Database: KOG eukaryal database 04/03
Posted date: Apr 14, 2003 1:07 PM
Number of letters in database: 30,389,216
Number of sequences in database: 60,738
Lambda K H
0.317 0.134 0.383
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 174,914,098
Number of Sequences: 60738
Number of extensions: 7471104
Number of successful extensions: 19211
Number of sequences better than 1.0e-05: 20
Number of HSP's better than 0.0 without gapping: 11
Number of HSP's successfully gapped in prelim test: 9
Number of HSP's that attempted gapping in prelim test: 18947
Number of HSP's gapped (non-prelim): 97
length of query: 3124
length of database: 30,389,216
effective HSP length: 125
effective length of query: 2999
effective length of database: 22,796,966
effective search space: 68368101034
effective search space used: 68368101034
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)