ORF STATUS Function Best COG Functional category Pathways and functional systems
r_klactV0291 check: MH O KOG1871 Posttranslational modification, protein turnover, chaperones Ubiquitin-specific protease
Only best alignment is shown:
BLASTP 2.2.3 [May-13-2002]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= r_klactV0291 104991 107312 774
(774 letters)
Database: KOG eukaryal database 04/03
60,738 sequences; 30,389,216 total letters
Searching..................................................done
Color Key for Alignment Scores: 
Score E
Sequences producing significant alignments: (bits) Value
YER151c [O] KOG1871 Ubiquitin-specific protease 503 e-142
SPBP8B7.21 [O] KOG1871 Ubiquitin-specific protease 178 3e-44
Hs22067085 [O] KOG1871 Ubiquitin-specific protease 153 8e-37
7292013_2 [O] KOG1871 Ubiquitin-specific protease 111 5e-24
YNL186w [O] KOG1870 Ubiquitin C-terminal hydrolase 70 1e-11
YER098w [O] KOG1864 Ubiquitin-specific protease 67 8e-11
SPAC13A11.04c [O] KOG1867 Ubiquitin-specific protease 64 7e-10
YER144c [O] KOG1868 Ubiquitin C-terminal hydrolase 62 3e-09
Hs4827054 [O] KOG1868 Ubiquitin C-terminal hydrolase 62 4e-09
YDR069c [O] KOG1868 Ubiquitin C-terminal hydrolase 61 7e-09
7295432 [O] KOG1865 Ubiquitin carboxyl-terminal hydrolase 61 7e-09
7295645 [O] KOG1868 Ubiquitin C-terminal hydrolase 60 2e-08
SPBC1703.12 [O] KOG1864 Ubiquitin-specific protease 59 2e-08
At4g39910 [O] KOG1864 Ubiquitin-specific protease 59 2e-08
At4g17890_2 [O] KOG1865 Ubiquitin carboxyl-terminal hydrolase 59 2e-08
At5g46740 [O] KOG1865 Ubiquitin carboxyl-terminal hydrolase 59 3e-08
At3g14400 [O] KOG1865 Ubiquitin carboxyl-terminal hydrolase 59 4e-08
SPBC713.02c [O] KOG1863 Ubiquitin carboxyl-terminal hydrolase 58 5e-08
YBL067c [O] KOG1864 Ubiquitin-specific protease 57 1e-07
7300926 [O] KOG1864 Ubiquitin-specific protease 57 1e-07
Hs18594540 [O] KOG1871 Ubiquitin-specific protease 56 2e-07
Hs18583486 [O] KOG1871 Ubiquitin-specific protease 55 3e-07
At4g24560 [O] KOG1865 Ubiquitin carboxyl-terminal hydrolase 55 4e-07
At2g22310 [O] KOG1864 Ubiquitin-specific protease 55 4e-07
At2g40930 [O] KOG1870 Ubiquitin C-terminal hydrolase 54 7e-07
SPCC188.08c [O] KOG1863 Ubiquitin carboxyl-terminal hydrolase 54 9e-07
YMR223w [O] KOG1867 Ubiquitin-specific protease 54 1e-06
7302097 [O] KOG1866 Ubiquitin carboxyl-terminal hydrolase 54 1e-06
Hs20540195 [O] KOG1865 Ubiquitin carboxyl-terminal hydrolase 53 2e-06
Hs14149817 [O] KOG1867 Ubiquitin-specific protease 53 2e-06
At2g24640 [O] KOG1865 Ubiquitin carboxyl-terminal hydrolase 53 2e-06
7303210 [O] KOG1870 Ubiquitin C-terminal hydrolase 53 2e-06
CE03146 [O] KOG1870 Ubiquitin C-terminal hydrolase 53 2e-06
7300711 [O] KOG1868 Ubiquitin C-terminal hydrolase 53 2e-06
Hs11641425 [O] KOG1866 Ubiquitin carboxyl-terminal hydrolase 52 3e-06
Hs11641423 [O] KOG1866 Ubiquitin carboxyl-terminal hydrolase 52 3e-06
At3g11910 [O] KOG1863 Ubiquitin carboxyl-terminal hydrolase 52 3e-06
YFR010w [O] KOG1872 Ubiquitin-specific protease 52 3e-06
YMR304w [O] KOG1863 Ubiquitin carboxyl-terminal hydrolase 51 6e-06
SPCC1682.12c [O] KOG1865 Ubiquitin carboxyl-terminal hydrolase 51 6e-06
SPCC16A11.12c [O] KOG1870 Ubiquitin C-terminal hydrolase 51 8e-06
>YER151c [O] KOG1871 Ubiquitin-specific protease
Length = 912
Score = 503 bits (1294), Expect = e-142
Identities = 266/527 (50%), Positives = 354/527 (66%), Gaps = 20/527 (3%)
Query: 264 SWSKLAAGSLGKPKQQLAVTNLASKKGKKYVPPSVKSPEPLGSVALRVCFDKNFTNHTLQ 323
S + +AA ++GK L ++ KK KKYVPPS K EPLGS+ALR+CFD +F ++ L+
Sbjct: 386 SSTNMAAATIGKSSSPL-LSKQPQKKDKKYVPPSTKGIEPLGSIALRMCFDPDFISYVLR 444
Query: 324 STKAKKLIT--ELVPRGIYNKGSICFISSVLQLLIHCRSFVNLLNVIHT-TTVSRTNSVS 380
+ + I ++PRGI N+ +ICF+SSVLQ+L++C+ F++++NV+ T T SR + S
Sbjct: 445 NKDVENKIPVHSIIPRGIINRANICFMSSVLQVLLYCKPFIDVINVLSTRNTNSRVGTSS 504
Query: 381 -PLLNACMDVFKRFDRETI----------VNELNXXXXXXXXXXXXXXXXXXIISIDPEP 429
LL+AC+ ++K+FD+ET + ++ P+
Sbjct: 505 CKLLDACLTMYKQFDKETYEKKFLENADDAEKTTESDAKKSSKSKSFQHCATADAVKPDE 564
Query: 430 FYKSISTLPKFKDLTWGRQEDAEEFLTHMLDQLHEEFIGSINTLNSNDILNIFQSLQEDD 489
FYK++ST+PKFKDL WG QEDAEEFLTH+LDQLHEE I +I+ L N+I N+ QS+ ++
Sbjct: 565 FYKTLSTIPKFKDLQWGHQEDAEEFLTHLLDQLHEELISAIDGLTDNEIQNMLQSINDEQ 624
Query: 490 QKVFFLKYISKYKSASFAEKPEQSLKALFEKYKQTNDLSDEEDX--XXXXXXXXXXXXXX 547
KVFF++ +S+Y A F + LK L EKY ND S EE+
Sbjct: 625 LKVFFIRNLSRYGKAEFIKNASPRLKELIEKYGVINDDSTEENGWHEVSGSSKRGKKTKT 684
Query: 548 XXXRITEVESSPISTIFGGQFRSVLDTPQNKESQSITYDPFQTIQLDISSPDVIDLESAF 607
R E+ SPIS +FGGQFRSVLD P NKESQSIT DPFQTIQLDIS V DLE+AF
Sbjct: 685 AAKRTVEIVPSPISKLFGGQFRSVLDIPNNKESQSITLDPFQTIQLDISDAGVNDLETAF 744
Query: 608 KKFSEQESIELKSSSGNDVEAKKHTCIDKLPQALLIQFKRFSFVSQSSK-NDLSNYNSFN 666
KKFSE E + KSSSGNDVEAKK T IDKLPQ LLIQFKRFSF++ +K N ++NYN++N
Sbjct: 745 KKFSEYELLPFKSSSGNDVEAKKQTFIDKLPQVLLIQFKRFSFINNVNKDNAMTNYNAYN 804
Query: 667 GRIEKIRKMVKYNHELTIPKESISP-NLVSTSNSEESFKYYLSGVIYHHGVSPSGGHYTC 725
GRIEKIRK +KY HEL IP+ES+S L + ++ + +Y L+GVIYHHGVS GGHYT
Sbjct: 805 GRIEKIRKKIKYGHELIIPEESMSSITLKNNTSGIDDRRYKLTGVIYHHGVSSDGGHYTA 864
Query: 726 DVYDKDLDKWYRIDDVNVDEIKNKEDILRSGDSASDSRTAYILLYEK 772
DVY + +KWYRIDDVN+ E+++ +D+L+ G+ ASDSRTAYIL+Y+K
Sbjct: 865 DVYHSEHNKWYRIDDVNITELED-DDVLKGGEEASDSRTAYILMYQK 910
>SPBP8B7.21 [O] KOG1871 Ubiquitin-specific protease
Length = 512
Score = 178 bits (451), Expect = 3e-44
Identities = 133/447 (29%), Positives = 196/447 (43%), Gaps = 74/447 (16%)
Query: 336 PRGIYNKGSICFISSVLQLLIHCRSFVNLLNVIHTTTVSRTNSVSPLLNACMDVFKRFDR 395
PRG N G+ICF++S+LQ L++C F NLL I+ +PL+ + + + F
Sbjct: 132 PRGFINTGNICFMNSILQALMYCVPFYNLLKQINRMVPYNFERTTPLIESLTMLSRDFRE 191
Query: 396 ETIVNELNXXXXXXXXXXXXXXXXXXIISIDPEPFYKSISTLPKFKDLTWGRQEDAEEFL 455
+ +L SI PE Y + P+F+ L G QEDAEEFL
Sbjct: 192 YSEKFDLQGD------------------SILPEVVYSATKGNPRFEMLQTGEQEDAEEFL 233
Query: 456 THMLDQLHEEFIGSINTLNSNDILNIFQSLQEDDQKVFFLKYISKYKSASFAEKPEQSLK 515
LD+LHEEF+ +++ + LK + P+ +K
Sbjct: 234 NLFLDELHEEFVR--------------------ERRHYLLKNDER--------NPKSDIK 265
Query: 516 ALFEKYKQTNDLSDEEDXXXXXXXXXXXXXXXXXXRITEVESSPISTIFGGQFRSVLDTP 575
+ D+ R VE SPIS IFGGQ RS L P
Sbjct: 266 ISNGIKSGLDSFDDQSSVEASGWTEVGKNKKPVIARSATVERSPISQIFGGQLRSTLRVP 325
Query: 576 QNKESQSITYDPFQTIQLDISSPDVIDLESAFKKFSEQESIELKSSSGNDVEAKKHTCID 635
++S + +PFQ +QLDI + D+ + A + + E + SS +V A K I+
Sbjct: 326 SARDS--VLLEPFQPLQLDIQAEDIHSVIDALEHMTAPEILPEWHSSKGNVTATKQMYIE 383
Query: 636 KLPQALLIQFKRFSFVSQSSKNDLSNYNSFNGRIEKIRKMVKYNHELTIPKESISPNLVS 695
LP L++ KRF + + +G +K K + Y L+IP+ SP++
Sbjct: 384 SLPPVLILHLKRFFYEA-------------SGGTQKNYKPIAYPARLSIPQNVFSPSVRG 430
Query: 696 TSNSEESFKYYLSGVIYHHGVSPSGGHYTCDVYDKDLDKWYRIDDVNVDEIKNKEDILRS 755
+ + E Y L+ V+YHHG S SGGHYT DV D W+RIDD ++ + D+ S
Sbjct: 431 SIHPE----YDLNAVVYHHGTSASGGHYTVDVQQLDKSGWFRIDDTHIHRVP-IHDVENS 485
Query: 756 GDSASDS--------RTAYILLYEKSS 774
SA S R AY+L Y + S
Sbjct: 486 ELSADPSLSKLGHGDRVAYLLFYTRRS 512
>Hs22067085 [O] KOG1871 Ubiquitin-specific protease
Length = 798
Score = 153 bits (387), Expect = 8e-37
Identities = 145/553 (26%), Positives = 237/553 (42%), Gaps = 84/553 (15%)
Query: 233 DPTAPPRSNTAXXXXXXXXXXXXXAQTLPV---KSWSKLAAGSLGKPKQQLAVTNLASKK 289
DPT P ++ TLPV KSW+ L S KP V + +K
Sbjct: 313 DPTKPESASPPADGTGSASG------TLPVSQPKSWASLFHDS--KPSSSSPVAYVETKY 364
Query: 290 GKKYVPPSVKSPE--------PLGSVALRVCFDKNFTNHTLQSTKAKKLITELVPRGIYN 341
+ P V + P+ + + + N TL L PRG+ N
Sbjct: 365 SPPAISPLVSEKQVEVKEGLVPVSEDPVAIKIAELLENVTLIHKPVS-----LQPRGLIN 419
Query: 342 KGSICFISSVLQLLIHCRSFVNLLNVIHT-TTVSRTNSVSPLLNACMDVFKRFDRETIVN 400
KG+ C+I++ LQ L+ C +L+ I + V R + +P++++ + + F +
Sbjct: 420 KGNWCYINATLQALVACPPMYHLMKFIPLYSKVQRPCTSTPMIDSFVRLMNEFTNMPVPP 479
Query: 401 ELNXXXXXXXXXXXXXXXXXXIISIDPEPFYKSISTLPKFKDLTWGRQEDAEEFLTHMLD 460
+ + +P Y+ + T+ K GRQEDAEE+L +L+
Sbjct: 480 KPRQALGDKIVRDIRPGA-----AFEPTYIYRLL-TVNKSSLSEKGRQEDAEEYLGFILN 533
Query: 461 QLHEEFIGSINTLNSNDILNIFQSLQEDDQKVFFLKYISKYKSASFAEKPEQSLKALFEK 520
LHEE +LN+ + L ++K+ + K S + E+ EQ + ++
Sbjct: 534 GLHEE------------MLNLKKLLSPSNEKLT-ISNGPKNHSVNEEEQEEQG-EGSEDE 579
Query: 521 YKQTNDLSDEEDXXXXXXXXXXXXXXXXXXRITEVESSPISTIFGGQFRSVLDTPQNKES 580
++Q + R + +PI+ IFGG RSV+ +KES
Sbjct: 580 WEQVGPRNK-----------------TSVTRQADFVQTPITGIFGGHIRSVVYQQSSKES 622
Query: 581 QSITYDPFQTIQLDISSPDVIDLESAFKKFSEQESIE-LKSSSGNDVEAKKHTCIDKLPQ 639
T PF T+QLDI S + ++ A + +ES++ + + +VE + ++KLP
Sbjct: 623 A--TLQPFFTLQLDIQSDKIRTVQDALESLVARESVQGYTTKTKQEVEISRRVTLEKLPP 680
Query: 640 ALLIQFKRFSFVSQSSKNDLSNYNSFNGRIEKIRKMVKYNHELTIPKESISPNLVSTSNS 699
L++ KRF + G +K+ K ++Y +L I KE +SP V N
Sbjct: 681 VLVLHLKRFVYEK-------------TGGCQKLIKNIEYPVDLEISKELLSPG-VKNKNF 726
Query: 700 EESFKYYLSGVIYHHGVSPSGGHYTCDVYDKDLDKWYRIDDVNVDEIKNKEDILRSGDSA 759
+ Y L V+YHHG S +GGHYT DV+ L+ W RIDD V I + + + +
Sbjct: 727 KCHRTYRLFAVVYHHGNSATGGHYTTDVFQIGLNGWLRIDDQTVKVINQYQVVKPTAE-- 784
Query: 760 SDSRTAYILLYEK 772
RTAY+L Y +
Sbjct: 785 ---RTAYLLYYRR 794
>7292013_2 [O] KOG1871 Ubiquitin-specific protease
Length = 414
Score = 111 bits (277), Expect = 5e-24
Identities = 109/447 (24%), Positives = 171/447 (37%), Gaps = 78/447 (17%)
Query: 334 LVPRGIYNKGSICFISSVLQLLIHCRSFVNLLNVIHTTTVSRTNSVSPLLNACMDVFKRF 393
L PRG+ N+ + C+I+S+LQ L+ C F NLL I + +P +NA M F
Sbjct: 4 LRPRGLTNRSNYCYINSILQALLGCSPFYNLLRSIPKQAAVLSEVKTPTVNAMMSFMTNF 63
Query: 394 DR-----ETIVNELNXXXXXXXXXXXXXXXXXXIISIDPEPFYKSISTLPKFKDLTWGRQ 448
+N LN ++ +P YK + ++ GRQ
Sbjct: 64 SSLPSGLRLRLNNLNKGSQSKGKDDFVGSDLQCDMAFEPTEIYKLWND--SREEHVEGRQ 121
Query: 449 EDAEEFLTHMLDQLHEEFIGSINTLNSNDILNIFQSLQEDDQKVFFLKYISKYKSASFAE 508
EDAEEFL ++L++L++E + I K I K +
Sbjct: 122 EDAEEFLGYVLNKLNDEMLEVI-------------------------KLIDKPTPQQNGQ 156
Query: 509 KPEQSLKALFEKYKQTNDLSDEEDXXXXXXXXXXXXXXXXXXRITEVESSPISTIFGGQF 568
+P ++ ED R T+ +P+S IF G+
Sbjct: 157 EP-----------------AEPEDGGDVWQMICNNRNKGSVTRQTDFGRTPVSDIFRGEL 199
Query: 569 RSVLDTPQNKESQSITYDPFQTIQLDISSPDVIDLESAFKKFSEQESIE--LKSSSGNDV 626
RS L + E + PF T+QL+I ++ A + ++ +E S + +V
Sbjct: 200 RSRLQ--REGEHSTDVIQPFFTLQLNIEK--AASVKEALEILVGRDQLEGVTGSKTKQEV 255
Query: 627 EAKKHTCIDKLPQALLIQFKRFSFVSQSSKNDLSNYNSFNGRIEKIRKMVKYNHELTIPK 686
A + ++KLP L++ K F + S KI K V + EL I
Sbjct: 256 VAWQQMTLEKLPVVLILHLKYFDYRSDGCT--------------KILKKVDFPVELKIDA 301
Query: 687 ESISPNLVSTSNSEESFKYYLSGVIYHHGVSPSGGHYTCDVYDKDLDKWYRIDDVNVDEI 746
+ + S S++ Y L V+YH G S GHY DV+ W R DD +V +
Sbjct: 302 KILG----SKKTSQKQRAYRLFAVVYHDGKEASKGHYITDVFHTGYSSWLRYDDSSVKPV 357
Query: 747 KNKEDILRSGDSASDSRTAYILLYEKS 773
K + R Y+L Y +S
Sbjct: 358 SEKHVL-----QPHTPRVPYLLYYRRS 379
>YNL186w [O] KOG1870 Ubiquitin C-terminal hydrolase
Length = 792
Score = 70.1 bits (170), Expect = 1e-11
Identities = 112/496 (22%), Positives = 188/496 (37%), Gaps = 90/496 (18%)
Query: 292 KYVPPSVKSPEPLGSVALRVCFDKNFTNH-TLQSTKAKK----LITELVPRGIYNKGSIC 346
K+ S+ P + +++ F++N + +L ST+ K T L PRG+ N G C
Sbjct: 312 KHKSRSITPPVTISNLSNFYQFNENINDRGSLNSTRIVKNWGDKFTNLKPRGLLNHGVTC 371
Query: 347 FISSVLQLLIHCRSFVNLLNVI----HTTTVSRTNSVSPLLNACMDVFKRFDRETIVNEL 402
+ ++ +Q ++H S + L I + +T+S+ NSVS L + K+ N
Sbjct: 372 YTNAAVQAMLHIPSIQHYLFDILMGKYDSTISK-NSVSYTL---AETSKKMWLPVSKNPR 427
Query: 403 NXXXXXXXXXXXXXXXXXXIISIDPEPFYKSISTLPKFKDLTWGRQEDAEEFLTHMLDQL 462
I+P+ + + W +QED+ E+ ++ +L
Sbjct: 428 KNVSASY---------------INPKHLISRLDDINCMMS-EW-QQEDSHEYFMSLMSRL 470
Query: 463 HEEFIGSINTLNSNDILNIFQSLQEDDQKVFFLKYISKYKSASFAEKPEQSLKALF---- 518
E+ + + L + I +IF L LK I KS K EQ L
Sbjct: 471 QEDSVPKGHKLIESIIYDIFGGL---------LKQIVTCKSCGSISKTEQPFYDLSLHLK 521
Query: 519 --EKYKQTNDLSDEEDXXXXXXXXXXXXXXXXXXRITEVESSPISTIFGGQFRSVLDTPQ 576
+K +DLS D + + SS ++ G F + D
Sbjct: 522 GKKKLDPNSDLSS--DSINGTSATTSTTTSNAATKPSLSSSSSVNLNNGSPFAAASDLSS 579
Query: 577 NKESQSITYDPFQTIQLDISSPDVIDLESAFKKFSEQESIELKSSSGNDVEAKKHTCIDK 636
SI ++I+ D +P++I ++ K + + A KH+ I +
Sbjct: 580 ANRRFSIE----KSIK-DFFNPELIKVDKEQKGY-------VCEKCHKTTNAVKHSSILR 627
Query: 637 LPQALLIQFKRFSFVSQSSKNDLSNYNSFNGRIEKIRKMVKYNHELTIPKESISPNLVST 696
P+ LL+ K+F F SS K+++ V Y L + + S L
Sbjct: 628 APETLLVHLKKFRFNGTSS--------------SKMKQAVSYPMFLDLTEYCESKEL--- 670
Query: 697 SNSEESFKYYLSGVIYHHGVSPSGGHYTCDVYDKDLDKWYRIDDVNVDEIKNKEDILRSG 756
KY L V+ H G S S GHY D W DD ++ I ++ D+L+
Sbjct: 671 -----PVKYQLLSVVVHEGRSLSSGHYIAHCKQPD-GSWATYDDEYIN-IISERDVLKEP 723
Query: 757 DSASDSRTAYILLYEK 772
+ AY LLY +
Sbjct: 724 N-------AYYLLYTR 732
>YER098w [O] KOG1864 Ubiquitin-specific protease
Length = 754
Score = 67.4 bits (163), Expect = 8e-11
Identities = 51/193 (26%), Positives = 86/193 (44%), Gaps = 28/193 (14%)
Query: 586 DPFQTIQLDISSPDVIDLESAFKKFSEQESIE-----LKSSSGNDVEAKKHTCIDKLPQA 640
+PF +++ + D++ K + ++E + + EA++ + +LP
Sbjct: 498 EPFLDFPIEVQGDEETDIQKMLKSYHQREMLNGVNKFYCNKCYGLQEAERMVGLKQLPHI 557
Query: 641 LLIQFKRFSFVSQSSKNDLSNYNSFNGRIEKIRKMVKYNHELTIPKESISPNLVSTSNSE 700
L + KRF + S+ SN FN K + LT+ ++ ST N+
Sbjct: 558 LSLHLKRFKY----SEEQKSNIKLFN----------KILYPLTL-------DVSSTFNTS 596
Query: 701 ESFKYYLSGVIYHHGVSPSGGHYTCDVYDKDLDKWYRIDDVNVDEIKNKEDILRSGDSAS 760
KY LSGV+ H G P GHY C + + W DD V+ IK +E +L+
Sbjct: 597 VYKKYELSGVVIHMGSGPQHGHYVC-ICRNEKFGWLLYDDETVESIK-EETVLQFTGHPG 654
Query: 761 DSRTAYILLYEKS 773
D TAY+L Y+++
Sbjct: 655 DQTTAYVLFYKET 667
>SPAC13A11.04c [O] KOG1867 Ubiquitin-specific protease
Length = 449
Score = 64.3 bits (155), Expect = 7e-10
Identities = 57/214 (26%), Positives = 91/214 (41%), Gaps = 39/214 (18%)
Query: 559 PISTIFGGQFRSVLDTPQNKESQSITYDPFQTIQLDISSPDVIDLESAFKKFSEQESIEL 618
PI IF G ++V+ T + + + + DP I LDI+ P L+ ++F +E ++
Sbjct: 260 PIHRIFSGSLKNVV-TCLDCKKERVAVDPLMDISLDINEPT---LQGCLERFVSKEKVQY 315
Query: 619 KSSSGNDVEAKKHTCIDKLPQALLIQFKRFSFVSQSSKNDLSNYNSFNGRIEKIRKMVKY 678
S A K DKLP + +Q KRF N+F KI K V Y
Sbjct: 316 SCHSCGSKNAIKQLVFDKLPPTICMQLKRF------------EQNNF-AMSTKIDKQVSY 362
Query: 679 NHELTIPKESISPNLVSTSNSEESFKYYLSGVIYHHGVSPSGGHYTCDVYDKDLDKWYRI 738
L + + +++ Y L V+ H G + GHY Y + ++W+ +
Sbjct: 363 PAFLR----------MRYNFNQDDVDYQLYSVVCHKGTLDT-GHYIAYTYYQ--NQWFLL 409
Query: 739 DDVNVDEIKNKEDILRSGDSASDSRTAYILLYEK 772
DD + E+K E +L S AY+L Y +
Sbjct: 410 DDTTIVEVKESE-VLNS--------QAYLLFYHE 434
>YER144c [O] KOG1868 Ubiquitin C-terminal hydrolase
Length = 805
Score = 62.4 bits (150), Expect = 3e-09
Identities = 65/256 (25%), Positives = 102/256 (39%), Gaps = 25/256 (9%)
Query: 522 KQTNDLSDEEDXXXXXXXXXXXXXXXXXXRITEVESSPISTIFGGQFRSVLDTPQNKESQ 581
K LSDEE+ R + S I +F GQ+ S L Q E
Sbjct: 568 KHLKQLSDEEERMREKMSIRKASALEWE-RFLLTDFSAIIDLFQGQYASRLQC-QVCEHT 625
Query: 582 SITYDPFQTIQLDISSPDVIDLESAFKKFSEQESIELKSSSGNDVEAKKHTC-----IDK 636
S TY F + + + ++ F++F++ E + + KK I +
Sbjct: 626 STTYQTFSVLSVPVPRVKTCNILDCFREFTKCERLGVDEQWSCPKCLKKQPSTKQLKITR 685
Query: 637 LPQALLIQFKRFSFVSQSSKNDLSNYNSFNGRIEKIRKMVKYNHELTIPKESISPNLVST 696
LP+ L+I KRF +Q +KN++ ++ + +NHE + ++ + T
Sbjct: 686 LPKKLIINLKRFD--NQMNKNNVFVQYPYSLDLTPYWAR-DFNHEAIVNED------IPT 736
Query: 697 SNSEESFKYYLSGVIYHHGVSPSGGHYTCDVYDKDLDKWYRIDDVNVDEIKNKEDILRSG 756
F+Y L GV H G S GGHYT VY WY DD I + +
Sbjct: 737 RGQVPPFRYRLYGVACHSG-SLYGGHYTSYVYKGPKKGWYFFDDSLYRPITFSTEFI--- 792
Query: 757 DSASDSRTAYILLYEK 772
+ +AY+L YE+
Sbjct: 793 -----TPSAYVLFYER 803
>Hs4827054 [O] KOG1868 Ubiquitin C-terminal hydrolase
Length = 1118
Score = 61.6 bits (148), Expect = 4e-09
Identities = 99/440 (22%), Positives = 164/440 (36%), Gaps = 118/440 (26%)
Query: 338 GIYNKGSICFISSVLQLLIHCRSFVNLLNV-IHTTTVSRTNSVSPLLNACMDVFKRFDRE 396
G+ N G+ C+++S+LQ L + + N + ++R+N LL +V + F
Sbjct: 778 GLRNLGNTCYMNSILQCLCNAPHLADYFNRNCYQDDINRSN----LLGHKGEVAEEFG-- 831
Query: 397 TIVNELNXXXXXXXXXXXXXXXXXXIISIDPEPFYKSISTLPKFKDLTWG-RQEDAEEFL 455
I+ L I P+ F T+ K D G Q+D++E L
Sbjct: 832 IIMKALWTGQYRY---------------ISPKDFK---ITIGKINDQFAGYSQQDSQELL 873
Query: 456 THMLDQLHEEFIGSINTLNSNDILNIFQSLQEDDQKVFFLKYISKYKSASFAEKPEQSLK 515
++D LHE+ LN D ++ D ++ +K+A A
Sbjct: 874 LFLMDGLHED-------LNKADNRKRYKEENND--------HLDDFKAAEHA-------- 910
Query: 516 ALFEKYKQTNDLSDEEDXXXXXXXXXXXXXXXXXXRITEVESSPISTIFGGQFRSVLDTP 575
++K+KQ N+ S I +F GQF+S +
Sbjct: 911 --WQKHKQLNE-------------------------------SIIVALFQGQFKSTVQC- 936
Query: 576 QNKESQSITYDPFQTIQLDISSPDVIDLESAFKKFSEQESIELK-----SSSGNDVEAKK 630
+S T++ F + L ++S L+ + FS++E + S ++ K
Sbjct: 937 LTCHKKSRTFEAFMYLSLPLASTSKCTLQDCLRLFSKEEKLTDNNRFYCSHCRARRDSLK 996
Query: 631 HTCIDKLPQALLIQFKRFSFVSQSSKNDLSNYNSFNGRIEKIRKMVKYNHELTIPKESIS 690
I KLP LL+ KRFS+ +GR ++ K + P E++
Sbjct: 997 KIEIWKLPPVLLVHLKRFSY---------------DGRWKQ-----KLQTSVDFPLENLD 1036
Query: 691 PNLVSTSNSEESFKYYLSGVIYHHGVSPSGGHYTCDVYDKDLDKWYRIDDVNVDEIKNKE 750
+ KY L V H+G GGHYT + +W++ DD V +I
Sbjct: 1037 LSQYVIGPKNNLKKYNLFSVSNHYG-GLDGGHYTAYCKNAARQRWFKFDDHEVSDI---- 1091
Query: 751 DILRSGDSASDSRTAYILLY 770
S+ S AYIL Y
Sbjct: 1092 -----SVSSVKSSAAYILFY 1106
>YDR069c [O] KOG1868 Ubiquitin C-terminal hydrolase
Length = 926
Score = 60.8 bits (146), Expect = 7e-09
Identities = 65/241 (26%), Positives = 98/241 (39%), Gaps = 46/241 (19%)
Query: 551 RITEVESSPISTIFGGQFRSVLDTPQNKESQSITYDPFQTIQLDI---SSPDVIDLESAF 607
R + S I +F GQ+ S L + S TY PF + + I +S + I +E F
Sbjct: 709 RFLTTDFSVIVDLFQGQYASRLKCKVCSHT-STTYQPFTVLSIPIPKKNSRNNITIEDCF 767
Query: 608 KKFSEQESIELKSS-----SGNDVEAKKHTCIDKLPQALLIQFKRFS--------FVSQS 654
++F++ E++E+ + K I +LP+ L++ KRF FV
Sbjct: 768 REFTKCENLEVDEQWLCPHCEKRQPSTKQLTITRLPRNLIVHLKRFDNLLNKNNDFVIYP 827
Query: 655 SKNDLSNY--NSFNGRIEKIRKMVKYNHELTIPKESISPNLVSTSNSEESFKYYLSGVIY 712
DL+ + N F+G + ++ + + FKY L GV
Sbjct: 828 FLLDLTPFWANDFDG----------------VFPPGVNDDELPIRGQIPPFKYELYGVAC 871
Query: 713 HHGVSPSGGHYTCDVYDKDLDK-WYRIDDVNVDEIKNKEDILRSGDSASDSRTAYILLYE 771
H G GGHYT V K L K W DD +KNK D + S AY+L Y
Sbjct: 872 HFGTL-YGGHYTAYV-KKGLKKGWLYFDDTKYKPVKNKADAINS--------NAYVLFYH 921
Query: 772 K 772
+
Sbjct: 922 R 922
>7295432 [O] KOG1865 Ubiquitin carboxyl-terminal hydrolase
Length = 577
Score = 60.8 bits (146), Expect = 7e-09
Identities = 56/195 (28%), Positives = 80/195 (40%), Gaps = 29/195 (14%)
Query: 556 ESSPISTIFGGQFRSVLDTPQNKESQSITYDPFQTIQLDISSPDVIDLESAFKKFSEQES 615
E++P+ IFGG RS + + SIT+ FQ + LDI D LE AF+ +E
Sbjct: 293 ETTPLGQIFGGYLRSEVRC-LSCNHVSITFQHFQDLLLDIRKAD--SLEDAFEGHFSRER 349
Query: 616 IELKS----SSGNDVEAKKHTCIDKLPQALLIQFKRFSFVSQSSKNDLSNYNSFNGRIEK 671
+E V A K +++ P L IQ KRFS + N L+ SF RI+
Sbjct: 350 LEDMGYKCEGCKKKVSATKQFSLERAPITLCIQLKRFSMIG----NKLTKQISFKSRIDL 405
Query: 672 IRKMVKYNHELTIPKESISPNLVSTSNSEESFKYYLSGVIYHHGVSPSGGHYTCDVYDKD 731
+ + S + + Y L ++ H G S GHYT + D
Sbjct: 406 SKYAAR-----------------SQAAQAQPLTYRLVSMVTHLGASQHCGHYTA-IGSTD 447
Query: 732 LDKWYRIDDVNVDEI 746
+Y DD V I
Sbjct: 448 TGSFYNFDDSYVRPI 462
>7295645 [O] KOG1868 Ubiquitin C-terminal hydrolase
Length = 857
Score = 59.7 bits (143), Expect = 2e-08
Identities = 96/441 (21%), Positives = 160/441 (35%), Gaps = 121/441 (27%)
Query: 338 GIYNKGSICFISSVLQLLIHCRSFVNLLNVIHTTTVSRTNSVSPLLNACMDVFKRFDRET 397
G+ N G+ CF++SV+Q L H + L H + T + F +
Sbjct: 533 GLRNIGNTCFMNSVIQCLSHTQELTRFLRSHHGSRSLSTKD--------QQILHEFAK-- 582
Query: 398 IVNELNXXXXXXXXXXXXXXXXXXIISIDPEPFYKSISTLPKFKDLTWGRQEDAEEFLTH 457
++ E+ + ++ P ++ ST K + + Q+DA+EFL
Sbjct: 583 LIQEM---------------WTANVHTVTPMELKRAFST--KHRMYSDYNQQDAQEFLRF 625
Query: 458 MLDQLHEEFIGSINTLNSNDILNIFQSLQEDDQKVFFLKYISKYKSASFAEKPEQSLKAL 517
LD LH ++N+ + LNI DD +S K A
Sbjct: 626 FLDSLHS----ALNSGVKGETLNI------DDN-------LSDNKKADLT---------- 658
Query: 518 FEKYKQTNDLSDEEDXXXXXXXXXXXXXXXXXXRITEVESSPISTIFGGQFRSVLDTPQN 577
+E Y T E+S + +F GQ +S L
Sbjct: 659 WEWY-------------------------------TRHENSLVRDLFVGQLKSTLKCTTC 687
Query: 578 KESQSITYDPFQTIQLDISSPDVIDLESAFKKFSEQESI---ELKSSSGNDVEAK--KHT 632
+ S+T+DPF + + + S LE+ F +E + E+ + + K K
Sbjct: 688 GNT-SVTFDPFWDLSVPLPSSSRCKLEACLDLFIREEVLDGDEMPTCAKCKTRRKCTKSF 746
Query: 633 CIDKLPQALLIQFKRFSFVSQSSKNDLSNYNSFNGRIEKIRKMVKYNHELTIPKESISPN 692
I + P+ L+I KRF S++ + LSN F P N
Sbjct: 747 TIQRFPKYLVIHLKRF---SETRWSKLSNIVEF-------------------PTSDSELN 784
Query: 693 LVSTSNSEESFKYYLSGVIYHHGVSPSGGHYTCDVYDKDLDKWYRIDDVNVDEIKNKEDI 752
+ S + S +Y I +H S +GGHY KW+ +D V + ++ +
Sbjct: 785 MGSYGANSNSNVHYSLYAISNHMGSTAGGHYVALCKHPVSRKWHEFNDNIVSDALSENHL 844
Query: 753 LRSGDSASDSRTAYILLYEKS 773
+ S +AYIL YE++
Sbjct: 845 V--------SSSAYILFYERT 857
>SPBC1703.12 [O] KOG1864 Ubiquitin-specific protease
Length = 585
Score = 59.3 bits (142), Expect = 2e-08
Identities = 54/196 (27%), Positives = 81/196 (40%), Gaps = 28/196 (14%)
Query: 581 QSITYDPFQTIQLDISSPDVIDLESAFKKFSEQESIELKSSSGNDV-----EAKKHTCID 635
++IT + L I + + S + FS E + K+ DV EA+K I
Sbjct: 248 ENITSRDESFLDLSIDIENHTSVTSCLRSFSASEMLSSKNKFHCDVCKSLQEAEKRMKIK 307
Query: 636 KLPQALLIQFKRFSFVSQSSKNDLSNYNSFNGRIEKIRKMVKYNHELTIPKESISPNLVS 695
KLP+ L + KRF YN +K+ + + +E+ + +
Sbjct: 308 KLPKILSLHLKRFK------------YNETQEGHDKLFYTIVFTNEMRL--------FTT 347
Query: 696 TSNSEESFK-YYLSGVIYHHGVSPSGGHYTCDVYDKDLDKWYRIDDVNVDEIKNKEDILR 754
T ++E + + YYLS VI H G P GHY V K W DD NV + N+ + R
Sbjct: 348 TEDAENAERMYYLSSVIVHVGGGPHRGHYVSIVRTKTYG-WVLFDDENVTPV-NENYLQR 405
Query: 755 SGDSASDSRTAYILLY 770
TAY+L Y
Sbjct: 406 FFGDQPGQATAYVLFY 421
>At4g39910 [O] KOG1864 Ubiquitin-specific protease
Length = 371
Score = 59.3 bits (142), Expect = 2e-08
Identities = 102/446 (22%), Positives = 154/446 (33%), Gaps = 116/446 (26%)
Query: 338 GIYNKGSICFISSVLQLLIHCRSFVNLLNVIHTTTVSRTNSVSPLLNACMDVFKRFDRET 397
G N G+ C+ +SVLQ L C F L +T+ S ++ L+ D+F + +
Sbjct: 24 GFENFGNTCYCNSVLQALYFCVPFREQLLEYYTSNKSVADAEENLMTCLADLFSQISSQK 83
Query: 398 IVNELNXXXXXXXXXXXXXXXXXXIISIDPEPFYKSISTLPKFKDLTWG-RQEDAEEFLT 456
+ I P+ F + L K +L +DA EFL
Sbjct: 84 KKTGV----------------------IAPKRF---VQRLKKQNELFRSYMHQDAHEFLN 118
Query: 457 HMLDQLHEEFIGSINTLNSNDILNIFQSLQEDDQKVFFLKYISKYKSASFAEKPEQSLKA 516
++L N++++I + K S + PE+
Sbjct: 119 YLL----------------NEVVDILEKEA---------KATKTEHETSSSSSPEKIANG 153
Query: 517 LFEKYKQTNDLSDEEDXXXXXXXXXXXXXXXXXXRITEVESSPISTIFGGQFRSVLDTPQ 576
L K Q N + V PI T F+ +L
Sbjct: 154 L--KVPQANGV---------------------------VHKEPIVTWVHNIFQGILTNET 184
Query: 577 NK---ESQSITYDPFQTIQLDISSPDVIDLESAFKKFSEQESIELKSSSGNDV-----EA 628
E+ + + F + LDI I S K FS E++ + D EA
Sbjct: 185 RCLRCETVTARDETFLDLSLDIEQNSSIT--SCLKNFSSTETLHAEDKFFCDKCCSLQEA 242
Query: 629 KKHTCIDKLPQALLIQFKRFSFVSQSSKNDLSNYNSFNGRIEKIRKMVKYNHELTIPKES 688
+K I K P L+I KRF ++ Q GR +K+ V + EL
Sbjct: 243 QKRMKIKKPPHILVIHLKRFKYIEQL------------GRYKKLSYRVVFPLEL------ 284
Query: 689 ISPNLVSTSNSEESFKYYLSGVIYHHGVSPSGGHYTCDVYDKDLDKWYRIDDVNVDEIKN 748
L +T +Y L V+ H G P+ GHY V K + W DD NV+ I+
Sbjct: 285 ---KLSNTVEPYADVEYSLFAVVVHVGSGPNHGHYVSLV--KSHNHWLFFDDENVEMIEE 339
Query: 749 KEDILRSGDS---ASDSRTAYILLYE 771
G S +S++ YIL YE
Sbjct: 340 SAVQTFFGSSQEYSSNTDHGYILFYE 365
>At4g17890_2 [O] KOG1865 Ubiquitin carboxyl-terminal hydrolase
Length = 544
Score = 59.3 bits (142), Expect = 2e-08
Identities = 61/201 (30%), Positives = 91/201 (44%), Gaps = 38/201 (18%)
Query: 577 NKESQSITYDPFQTIQLDISSPDVIDLESAFKKFSEQESIELKSSSGN---DVEAKKHTC 633
N + S TY+ +++ L + DV L SA + F+ E ++ + + N V +K
Sbjct: 157 NCDYVSETYE--KSVGLSLEIEDVDTLGSALESFTRVEKLDEQLTCDNCNEKVSKEKQLL 214
Query: 634 IDKLPQALLIQFKRFSFVSQSSKNDLSNYNSFNGR-IEKIRKMVKYNHELTIPKESISPN 692
+DKLP KRF KN NG +EKI K VK E+ + P
Sbjct: 215 LDKLPLVATFHLKRF-------KN--------NGLYMEKIYKHVKIPLEI-----DLQPY 254
Query: 693 LVSTSNSEESFKYYLSGVIYHHGVSPSGGHYTCDVYDKDLDK-WYRIDDVNVDEIKNKED 751
+ + +E S KY+L ++ H G S + GHY+ Y + K W+ DD V I ED
Sbjct: 255 MRNIQENEVSTKYHLYALVEHFGYSVAYGHYSS--YVRSAPKIWHHFDDSKVTRI--DED 310
Query: 752 ILRSGDSASDSRTAYILLYEK 772
++ S DS YIL Y +
Sbjct: 311 MVLSQDS-------YILFYAR 324
>At5g46740 [O] KOG1865 Ubiquitin carboxyl-terminal hydrolase
Length = 732
Score = 58.9 bits (141), Expect = 3e-08
Identities = 63/216 (29%), Positives = 94/216 (43%), Gaps = 35/216 (16%)
Query: 560 ISTIFGGQFRSVLDTPQNKESQSITYDPFQTIQLDISSPDVIDLESAFKKFSEQESIELK 619
+ +FGG S L N S S T++P L+I DV L A + F+ E +E +
Sbjct: 285 VDNVFGGGLMSTLCCC-NCNSVSNTFEPSLGWSLEIE--DVNTLWKALESFTCVEKLEDQ 341
Query: 620 SSSGN---DVEAKKHTCIDKLPQALLIQFKRFSFVSQSSKNDLSNYNSFNGRIEKIRKMV 676
+ N V +K DKLP KRF+ ND +EKI +
Sbjct: 342 LTCDNCKEKVTKEKQLRFDKLPPVATFHLKRFT-------ND-------GVTMEKIFDHI 387
Query: 677 KYNHELTIPKESISPNLVSTSNSEESFKYYLSGVIYHHGVSPSGGHYTCDVYDKDLDKWY 736
++ EL +SP + S + E S +Y+L + H G+ + GHY+ V + W+
Sbjct: 388 EFPLEL-----DLSPFMSSNHDPEVSTRYHLYAFVEHIGIRATFGHYSSYVRSAP-ETWH 441
Query: 737 RIDDVNVDEIKNKEDILRSGDSASDSRTAYILLYEK 772
DD V I ++E +L SR AYIL Y +
Sbjct: 442 NFDDSKVTRI-SEERVL--------SRPAYILFYAR 468
>At3g14400 [O] KOG1865 Ubiquitin carboxyl-terminal hydrolase
Length = 661
Score = 58.5 bits (140), Expect = 4e-08
Identities = 60/228 (26%), Positives = 99/228 (43%), Gaps = 50/228 (21%)
Query: 557 SSPISTIFGGQFRSVLDTPQNKESQSITYDPFQTIQLDISSPDVIDLESAFKKFSEQESI 616
+S + IFGG +S + + ++S D I L+I L+S+ K S Q+
Sbjct: 133 NSVVKEIFGGALQSQVKC-LSCGAESNKADEIMDISLEI-------LQSSSVKESLQKFF 184
Query: 617 ELKSSSGND----------VEAKKHTCIDKLPQALLIQFKRFSFVSQSSKNDLSNYNSFN 666
+ + GN+ V A+K I + P L+IQ KRF + F
Sbjct: 185 QSEILDGNNKYRCESCEKLVTARKQMSILQAPNILVIQLKRFGGI-------------FG 231
Query: 667 GRIEKIRKMVKYNHELTIPKESISPNLVSTSNSEESFKYYLSGVIYHHGVSPSGGHYTCD 726
G+I+K ++ + + N +S ++ + +Y L G+I H G SP GHY
Sbjct: 232 GKIDKA---------ISFGEILVLSNFMSKASKDPQPEYKLFGIIVHSGFSPESGHYYAY 282
Query: 727 VYDKDLDKWYRIDDVNVDEIKNKEDILRSGDSASDSRTAYILLYEKSS 774
V D L +WY +D V + +++L S AYIL + +S+
Sbjct: 283 VKD-SLGRWYCCNDSFV-SLSTLQEVL--------SEKAYILFFSRSN 320
>SPBC713.02c [O] KOG1863 Ubiquitin carboxyl-terminal hydrolase
Length = 1129
Score = 58.2 bits (139), Expect = 5e-08
Identities = 58/210 (27%), Positives = 94/210 (44%), Gaps = 42/210 (20%)
Query: 553 TEVESSPISTIFGGQFRSVLDTPQ-NKESQSITYDPFQTIQLDISSPDVIDLESAFKKFS 611
TEVE++ ++ IF G+ +S + N ES + + F IQL++ D LE +F+
Sbjct: 330 TEVENA-LNDIFVGKMKSYVKCIDVNYESSRV--EDFWDIQLNVKGMDT--LEDSFR--- 381
Query: 612 EQESIELKSSSGNDV---------EAKKHTCIDKLPQALLIQFKRFSFVSQSSKNDLSNY 662
++I++++ +G++ +A K + LP L +Q KRF +
Sbjct: 382 --DAIQVETLTGDNKYYAEGHGLQDAHKGIIFESLPNVLQLQLKRFDY------------ 427
Query: 663 NSFNGRIEKIRKM-VKYNHELTIPKE-SISPNLVSTSNSEESFKYYLSGVIYHHGVSPSG 720
+ +R M VK N P E + P L T++ ES Y L GV+ H G G
Sbjct: 428 -------DMLRDMMVKINDRHEFPLEIDLEPYLSETADKSESHVYVLHGVLVHGG-DLHG 479
Query: 721 GHYTCDVYDKDLDKWYRIDDVNVDEIKNKE 750
GHY + + W++ DD V KE
Sbjct: 480 GHYYALIKPEKDSNWFKFDDDRVTRATIKE 509
>YBL067c [O] KOG1864 Ubiquitin-specific protease
Length = 688
Score = 56.6 bits (135), Expect = 1e-07
Identities = 44/192 (22%), Positives = 83/192 (42%), Gaps = 28/192 (14%)
Query: 586 DPFQTIQLDISSPDVIDLESAFKKFSEQESIELKSSSGNDV-----EAKKHTCIDKLPQA 640
+PF +++ + D++ K + ++E + + D EA++ + +LP
Sbjct: 499 EPFLDFPIEVQGDEETDIQEILKSYHQREMLNGSNKFYCDECCGLQEAERLVGLKQLPDT 558
Query: 641 LLIQFKRFSFVSQSSKNDLSNYNSFNGRIEKIRKMVKYNHELTIPKESISPNLVSTSNSE 700
L + KRF + S+ N FN ++ LT+ N+ S+ NS+
Sbjct: 559 LTLHLKRFKY----SEKQNCNIKLFNN----------IHYPLTL-------NVCSSINSK 597
Query: 701 ESFKYYLSGVIYHHGVSPSGGHYTCDVYDKDLDKWYRIDDVNVDEIKNKEDILRSGDSAS 760
KY L+G++ H G P GHY + + W DD V+ +K +E +L +
Sbjct: 598 VCQKYELAGIVVHMGGGPQHGHYV-SLCKHEKFGWLLFDDETVEAVK-EETVLEFTGESP 655
Query: 761 DSRTAYILLYEK 772
+ TAY+ ++
Sbjct: 656 NMATAYVCFIKR 667
>7300926 [O] KOG1864 Ubiquitin-specific protease
Length = 424
Score = 56.6 bits (135), Expect = 1e-07
Identities = 104/451 (23%), Positives = 157/451 (34%), Gaps = 73/451 (16%)
Query: 338 GIYNKGSICFISSVLQLLIHCRSFVNLLNVIHTTTVSRTNSVSPLLNACMDVFKRFDRET 397
G+ N G+ C+ +SVLQ L C+ F + LL+ D+F
Sbjct: 25 GLVNFGNTCYSNSVLQALYFCKPF---REKVLEYKAKNKRPKETLLSCLADLF------- 74
Query: 398 IVNELNXXXXXXXXXXXXXXXXXXIISIDPEPFYKSISTLPKFKD-LTWGRQEDAEEFLT 456
+ SI P+ F I+ L K K+ Q+DA EFL
Sbjct: 75 ---------------YSIATQKKKVGSIAPKKF---ITRLRKEKEEFDNYMQQDAHEFLN 116
Query: 457 HMLDQLHEEFIGSINTLNSNDILNIFQSLQEDDQKVFFLKYISKYKSASFAEKPEQSL-K 515
+++ ++E + N SN N + Q SK S S + S
Sbjct: 117 FLINHINEIILAERNAGPSNG--NPKATNQGGSTSAMASSIASKSSSTSNSNSNSNSTTN 174
Query: 516 ALFEKYKQTNDLSDEE---DXXXXXXXXXXXXXXXXXXRITEVESSP--ISTIFGGQFRS 570
+ T L+ D S P + IF G S
Sbjct: 175 SNGNSSNSTGSLNANTSVLDASGSLTATTTPIISGNGTGTNGANSEPTWVHEIFQGILTS 234
Query: 571 VLDTPQNKESQSITYDPFQTIQLDISSPDVIDLESAFKKFSEQESIELKSSSGND----- 625
N E+ S + F +Q+D+ I + FS E++ + D
Sbjct: 235 ETRC-LNCETVSSKDENFFDLQVDVDQNTSIT--HCLRCFSNTETLCSDNKFKCDNCCSY 291
Query: 626 VEAKKHTCIDKLPQALLIQFKRFSFVSQSSKNDLSNYNSFNGRIEKIRKMVKYNHELTIP 685
EA+K + KLP L + KRF ++ Q +++ +K +H + P
Sbjct: 292 QEAQKRMRVKKLPMILALHLKRFKYMEQFNRH------------------IKVSHRVVFP 333
Query: 686 KESISPNLVSTSNS--EESFKYYLSGVIYHHGVSPSGGHYTCDVYDKDLDKWYRIDDVNV 743
E L +TS+ Y L+ V+ H G P+ GHY V L W DD V
Sbjct: 334 LEL---RLFNTSDDAVNPDRLYDLTAVVIHCGSGPNRGHYISIVKSHGL--WLLFDDDMV 388
Query: 744 DEIKNK--EDIL-RSGDSASDSRTAYILLYE 771
D+I+ ED + D S T YIL Y+
Sbjct: 389 DKIEASTIEDFYGLTSDIHKSSETGYILFYQ 419
>Hs18594540 [O] KOG1871 Ubiquitin-specific protease
Length = 176
Score = 56.2 bits (134), Expect = 2e-07
Identities = 33/100 (33%), Positives = 51/100 (51%), Gaps = 3/100 (3%)
Query: 563 IFGGQFRSVLDTPQNKESQSITYDPFQTIQLDISSPDVIDLESAFKKFSEQESIE-LKSS 621
IFGG RSV+ KES T PF T+QLDI S + ++ A + +ES++ +
Sbjct: 26 IFGGHIRSVVYQQSAKESA--TLQPFFTLQLDIQSDKIRTVQDALESLVARESVQGYTTK 83
Query: 622 SGNDVEAKKHTCIDKLPQALLIQFKRFSFVSQSSKNDLSN 661
+ +VE + ++KLP L++ KRF + L N
Sbjct: 84 TEQEVEKSRRVTLEKLPPVLVLHLKRFVYEKTGGARSLLN 123
>Hs18583486 [O] KOG1871 Ubiquitin-specific protease
Length = 179
Score = 55.5 bits (132), Expect = 3e-07
Identities = 33/99 (33%), Positives = 51/99 (51%), Gaps = 3/99 (3%)
Query: 563 IFGGQFRSVLDTPQNKESQSITYDPFQTIQLDISSPDVIDLESAFKKFSEQESIE-LKSS 621
IFGG RSV+ KES T PF T+QLDI S + ++ A + +ES++ +
Sbjct: 26 IFGGHIRSVVYQQSAKESA--TLQPFFTLQLDIQSDKIRTVQDALESLVARESVQGYTTK 83
Query: 622 SGNDVEAKKHTCIDKLPQALLIQFKRFSFVSQSSKNDLS 660
+ +VE + ++KLP L++ KRF + LS
Sbjct: 84 TEQEVEISRRVTLEKLPPLLVLHLKRFVYEKTGGVRSLS 122
>At4g24560 [O] KOG1865 Ubiquitin carboxyl-terminal hydrolase
Length = 1008
Score = 55.1 bits (131), Expect = 4e-07
Identities = 58/225 (25%), Positives = 98/225 (42%), Gaps = 45/225 (20%)
Query: 556 ESSPISTIFGGQFRSVLDTPQNKESQSITYDPFQ-TIQLDISSPDVIDLESAFKKFSEQE 614
+++ I FGG RS + + + + T+++D D+ L+ A ++F+ E
Sbjct: 659 DTTLIGLTFGGYLRSKIKCMKCQVKSELREKMMDLTVEID---GDISTLDDALRRFTRTE 715
Query: 615 SIELKS-----SSGNDVEAKKHTCIDKLPQALLIQFKRFSFVSQSSKNDLSNYNSFNGRI 669
++ ++ S + AKK I + P L I KRF G+
Sbjct: 716 ILDGENKYRCGSCKSYERAKKKLKITEPPNVLTIALKRFQA----------------GKF 759
Query: 670 EKIRKMVKYNHELTIPKESISPNLVSTSNSEESFKYYLSGVIYHHGVSPSG--GHYTCDV 727
K+ K++++ L ++P + + SE+S Y L GVI H V + GHY C
Sbjct: 760 GKLNKLIRFPETL-----DLAPYV--SGGSEKSHDYKLYGVIVHLDVMNAAFSGHYVC-- 810
Query: 728 YDKDLDKWYRIDDVNVDEIKNKEDILRSGDSASDSRTAYILLYEK 772
Y ++ +KWY+ DD V + E IL G AY+L Y +
Sbjct: 811 YIRNQNKWYKADDSTV-VTSDVERILTKG--------AYMLFYAR 846
>At2g22310 [O] KOG1864 Ubiquitin-specific protease
Length = 365
Score = 55.1 bits (131), Expect = 4e-07
Identities = 63/228 (27%), Positives = 91/228 (39%), Gaps = 36/228 (15%)
Query: 555 VESSPISTIFGGQFRSVLDTPQNK---ESQSITYDPFQTIQLDISSPDVIDLESAFKKFS 611
V PI T F+ +L E+ + + F + LDI I S K FS
Sbjct: 158 VHKEPIVTWVHKIFQGILTNETRCLRCETVTARDETFLDLSLDIEQNSSIT--SCLKNFS 215
Query: 612 EQESIELKSSSGNDV-----EAKKHTCIDKLPQALLIQFKRFSFVSQSSKNDLSNYNSFN 666
E++ + D EA+K I K P L+I KRF ++ Q
Sbjct: 216 STETLHAEDKFFCDKCCSLQEAQKRMKIKKPPHILVIHLKRFKYMEQL------------ 263
Query: 667 GRIEKIRKMVKYNHELTIPKESISPNLVSTSNSEESFKYYLSGVIYHHGVSPSGGHYTCD 726
GR +K+ V + EL L +T + +Y L V+ H G P+ GHY
Sbjct: 264 GRYKKLSYRVVFPLEL---------KLSNTVDEYVDIEYSLFAVVVHVGSGPNHGHYVSL 314
Query: 727 VYDKDLDKWYRIDDVNVDEIKNKEDILRSGDS---ASDSRTAYILLYE 771
V K + W DD +V+ I+ G S +S++ YILLYE
Sbjct: 315 V--KSHNHWLFFDDESVEIIEESAVQTFFGSSQEYSSNTDHGYILLYE 360
>At2g40930 [O] KOG1870 Ubiquitin C-terminal hydrolase
Length = 914
Score = 54.3 bits (129), Expect = 7e-07
Identities = 44/148 (29%), Positives = 68/148 (45%), Gaps = 29/148 (19%)
Query: 627 EAKKHTCIDKLPQALLIQFKRFSFVSQSSKNDLSNYNSFNGRIEKIRKMVKYNHELTIPK 686
+A K + +LP+ L+I KRFS+ S+S K+ L + +F H+L + K
Sbjct: 789 QASKKLDLWRLPEVLVIHLKRFSY-SRSMKHKLETFVNFP------------IHDLDLTK 835
Query: 687 ESISPNLVSTSNSEESFKYYLSGVIYHHGVSPSGGHYTCDVYDKDLDKWYRIDDVNVDEI 746
V+ N + Y L + H+G SG HYT + D +WY DD ++ I
Sbjct: 836 ------YVANKNLSQPQLYELYALTNHYGGMGSG-HYTAHIKLLDDSRWYNFDDSHISHI 888
Query: 747 KNKEDILRSGDSASDSRTAYILLYEKSS 774
ED ++SG AY+L Y + S
Sbjct: 889 --NEDDVKSG-------AAYVLFYRRKS 907
>SPCC188.08c [O] KOG1863 Ubiquitin carboxyl-terminal hydrolase
Length = 1108
Score = 53.9 bits (128), Expect = 9e-07
Identities = 58/238 (24%), Positives = 103/238 (42%), Gaps = 41/238 (17%)
Query: 551 RITEVESSPISTIFGGQFRSVLDTPQNKESQSITYDPFQTIQLDISSPDVIDLESAFKKF 610
R T+VE++ ++ +F G+ +S + N +S + + IQL++ + +LE +F+ +
Sbjct: 311 RDTKVENA-LTNLFVGKMKSYIACV-NVNFESARSEDYWDIQLNVKG--MKNLEDSFRSY 366
Query: 611 SEQESIELKSSSGNDV----EAKKHTCIDKLPQALLIQFKRFSFVSQSSKNDLSNYNSFN 666
+ E++E + D EAKK + P L +Q KRF + + D+
Sbjct: 367 IQVETLEGDNCYFADTYGFQEAKKGVIFESFPPILHLQLKRFEY---DFERDM------- 416
Query: 667 GRIEKIRKMVKYNHELTIPKESISPNLVST-SNSEESFKYYLSGVIYHHGVSPSGGHYTC 725
M+K N P E + +S ++ ++ +Y L GV+ H G +G +Y
Sbjct: 417 --------MIKINDRYEFPLEFDAKAFLSPEADQSQNCEYVLYGVLVHSGDLHNGHYYAL 468
Query: 726 DVYDKDLDKWYRIDDVNVDEIKNKEDI-------------LRSGDSASDSRTAYILLY 770
+KD WY+ DD V +E + RS +AY+LLY
Sbjct: 469 LKTEKD-GPWYKYDDTRVTRATLREVLEENYGGDYIMHPPFRSPVKLKRFMSAYMLLY 525
>YMR223w [O] KOG1867 Ubiquitin-specific protease
Length = 471
Score = 53.5 bits (127), Expect = 1e-06
Identities = 54/215 (25%), Positives = 89/215 (41%), Gaps = 28/215 (13%)
Query: 560 ISTIFGGQFRSVLDTPQNKESQSITYDPFQTIQLDISSPDVI-DLESAFKKFSEQESIEL 618
+ T+F G S + P + + T DPF + LDI + + +F K + +
Sbjct: 275 VHTVFEGSLESSIVCPGCQNNSKTTIDPFLDLSLDIKDKKKLYECLDSFHKKEQLKDFNY 334
Query: 619 KSSSGNDVE-AKKHTCIDKLPQALLIQFKRFSFVSQSSKNDLSNYNSFNGRIEKIRKMVK 677
N + A K I KLP L++Q KRF + S L ++ IE +
Sbjct: 335 HCGECNSTQDAIKQLGIHKLPSVLVLQLKRFEHLLNGSNRKLDDF------IEFPTYLNM 388
Query: 678 YNHELTIPKESISPNLVSTSNSEESFKYYLSGVIYHHGVSPSGGHYT--CDVYDKDLDKW 735
N+ T K+ S N Y L G++ H G + + GHY C + +W
Sbjct: 389 KNYCSTKEKDKHSEN-----GKVPDIIYELIGIVSHKG-TVNEGHYIAFCKISG---GQW 439
Query: 736 YRIDDVNVDEIKNKEDILRSGDSASDSRTAYILLY 770
++ +D V I ++E++L+ AY+L Y
Sbjct: 440 FKFNDSMVSSI-SQEEVLK--------EQAYLLFY 465
>7302097 [O] KOG1866 Ubiquitin carboxyl-terminal hydrolase
Length = 2778
Score = 53.5 bits (127), Expect = 1e-06
Identities = 47/180 (26%), Positives = 78/180 (43%), Gaps = 24/180 (13%)
Query: 586 DPFQTIQLDISSPDVIDLESAFKKFSEQESIELKSSSGND-----VEAKKHTCIDKLPQA 640
+PF +DI + L + +++ + E +E + D V K C+ KLP
Sbjct: 1850 EPFSVFSVDIRNHS--SLTESLEQYVKGELLEGADAYHCDKCDKKVVTVKRVCVKKLPPV 1907
Query: 641 LLIQFKRFSF-VSQSSKNDLSNYNSFNGRIE----KIRKMVKYNHELTIPKESISPNLVS 695
L IQ KRF + + ++Y F ++ + + K E+ ++ N+
Sbjct: 1908 LAIQLKRFEYDYERVCAIKFNDYFEFPRILDMEPYTVSGLAKLEGEVVEVGDNCQTNV-- 1965
Query: 696 TSNSEESFKYYLSGVIYHHGVSPSGGHYTCDVYDKD----LDKWYRIDDVNVDEIKNKED 751
E+ KY L+G++ H G SGGHY + K+ +WY+ DD V E K ED
Sbjct: 1966 -----ETTKYELTGIVVHSG-QASGGHYFSYILSKNPANGKCQWYKFDDGEVTECKMHED 2019
>Hs20540195 [O] KOG1865 Ubiquitin carboxyl-terminal hydrolase
Length = 823
Score = 53.1 bits (126), Expect = 2e-06
Identities = 60/215 (27%), Positives = 92/215 (41%), Gaps = 33/215 (15%)
Query: 560 ISTIFGGQFRSVLDTPQNKESQSITYDPFQTIQLDISSPDVIDLESAFKKFSEQESIELK 619
+ IFGG RS + N + S T+DP+ I L+I + ++ A ++F + E ++ +
Sbjct: 230 VCQIFGGYLRSRVKC-LNCKGVSDTFDPYLDITLEIKAAQSVN--KALEQFVKPEQLDGE 286
Query: 620 SSSGNDVEAKKHTCIDKLPQALLIQFKRFSFVSQSSKNDLSNYNSFNGRIEKIRKMVKYN 679
+S K C +P + KRF+ S+ LS N KI K VKY
Sbjct: 287 NSY------KCSKCKKMVPAS-----KRFTIHRSSNVLTLSLKRFANFTGGKIAKDVKYP 335
Query: 680 HELTIPKESISPNLVSTSNSEESFKYYLSGVIYHHGVSPSGGHYTCDVYDKDLDKWYRID 739
L I PN E Y L V+ H G + GHY C + + WY+++
Sbjct: 336 EYLDIRPYMSQPN-------GEPIVYVLYAVLVHTGFNCHAGHYFCYIKASN-GLWYQMN 387
Query: 740 DVNVDEIKNKEDILRSGDSASD-SRTAYILLYEKS 773
D I+ + D S S+ AY+L Y +S
Sbjct: 388 D----------SIVSTSDIRSVLSQQAYVLFYIRS 412
>Hs14149817 [O] KOG1867 Ubiquitin-specific protease
Length = 712
Score = 53.1 bits (126), Expect = 2e-06
Identities = 55/206 (26%), Positives = 86/206 (41%), Gaps = 41/206 (19%)
Query: 560 ISTIFGGQFRSVLDTPQNKESQSITYDPFQTIQLDI------SSPDVID----LESAFKK 609
++ IF GQ S + T +++S T +PF + L+ S D+ + K
Sbjct: 465 VNNIFHGQLLSQV-TCLACDNKSNTIEPFWDLSLEFPERYQCSGKDIASQPCLVTEMLAK 523
Query: 610 FSEQESIELK---------------SSSGNDVEAKKHTCIDKLPQALLIQFKRFSFVSQS 654
F+E E++E K S EA+K I LPQ L + KRF + ++
Sbjct: 524 FTETEALEGKIYVCDQCNSKRRRFSSKPVVLTEAQKQLMICHLPQVLRLHLKRFRWSGRN 583
Query: 655 SKNDLSNYNSFNGRIEKIRKMVKYNHELTIPKESISPNLVSTSNSEESFKYYLSGVIYHH 714
++ + + F E+I M Y T+ +S+ P E F Y LS V+ HH
Sbjct: 584 NREKIGVHVGF----EEILNMEPYCCRETL--KSLRP---------ECFIYDLSAVVMHH 628
Query: 715 GVSPSGGHYTCDVYDKDLDKWYRIDD 740
G GHYT Y+ + W +D
Sbjct: 629 GKGFGSGHYTAYCYNSEGGFWVHCND 654
>At2g24640 [O] KOG1865 Ubiquitin carboxyl-terminal hydrolase
Length = 743
Score = 53.1 bits (126), Expect = 2e-06
Identities = 62/226 (27%), Positives = 95/226 (41%), Gaps = 44/226 (19%)
Query: 556 ESSPISTIFGGQFRSVLDTPQNKESQSITYDPFQTIQLDISSPDVIDLESAFKKFSEQES 615
E++ I IFGG +S + + S Y+ + ++I D + LE +F+ +E
Sbjct: 344 ETTLIQYIFGGLLQSQVQCTACS-NVSDQYENMMDLTVEIHG-DAVSLEECLDQFTAKEW 401
Query: 616 IE----LKSSSGND-VEAKKHTCIDKLPQALLIQFKRFSFVSQSSKNDLSNYNSFNGRIE 670
++ K +D V+A K I P L I KRF GR
Sbjct: 402 LQGDNLYKCDRCDDYVKACKRLSIRCAPNILTIALKRFQ----------------GGRFG 445
Query: 671 KIRKMVKYNHELTIPKESISPNLVSTSNSEESFKYYLSGVIYHHGVSPSG--GHYTCDVY 728
K+ K + + E+ + E S Y L VI H + + GHY C Y
Sbjct: 446 KLNKRISF-------PETFDLGPYMSGGGEGSDVYKLYAVIVHLDMLNASFFGHYIC--Y 496
Query: 729 DKDL-DKWYRIDDVNVDEIKNKEDILRSGDSASDSRTAYILLYEKS 773
KD WYRIDD V++++ ED+L S+ AY+LLY ++
Sbjct: 497 VKDFRGNWYRIDDSEVEKVE-LEDVL--------SQRAYMLLYSRT 533
>7303210 [O] KOG1870 Ubiquitin C-terminal hydrolase
Length = 857
Score = 53.1 bits (126), Expect = 2e-06
Identities = 47/145 (32%), Positives = 64/145 (43%), Gaps = 33/145 (22%)
Query: 630 KHTCIDKLPQALLIQFKRFSFVSQSSKNDLSNYNSFNGRIEKIRKMVKYNHELTIPKESI 689
K++ + LP+ L I KRF +NDLS Y+S K + ++ P E
Sbjct: 309 KYSRVLTLPEVLCIHLKRF-------RNDLS-YSS------------KISSDVYFPLEGF 348
Query: 690 S--PNLVSTSNSEESFKYYLSGVIYHHGVSPSGGHYTCDVYDKDLDKWYRIDDVNVDEIK 747
P + SE + Y LS VI HHG + GGHYTC + KWY DD V E+
Sbjct: 349 DMRPYIHKDCKSEVAI-YNLSSVICHHG-TVGGGHYTCFARNTLNGKWYEFDDQFVTEVS 406
Query: 748 NKEDILRSGDSASDSRTAYILLYEK 772
++ S AY+L Y K
Sbjct: 407 SE---------LVQSCQAYVLFYHK 422
>CE03146 [O] KOG1870 Ubiquitin C-terminal hydrolase
Length = 1095
Score = 52.8 bits (125), Expect = 2e-06
Identities = 54/180 (30%), Positives = 75/180 (41%), Gaps = 32/180 (17%)
Query: 600 VIDLESAFKKFSEQESIELKSSSGNDVEAKKHTCIDKLPQALLIQFKRFSFVSQSSKNDL 659
++DL S ++ +ES + N VEA K + +LP L+IQ KRF + +
Sbjct: 913 MLDLFSETERLKPEESWYCSTCKEN-VEATKKLQLYRLPPVLIIQLKRFVYTA------- 964
Query: 660 SNYNSFNGRIEKIRKMVKYNHELTIPKESI--SPNLVSTSNSEESFKYYLSGVIYHHGVS 717
Y S R K + V+Y P ES+ SP L TS S Y L+GV+ H G S
Sbjct: 965 FTYQSSMARRSKDTRSVEY------PLESLDMSPFLAETSPHPNSTMYDLTGVVCHSGNS 1018
Query: 718 PSGGHYTCDVYDKDLD------KWYRIDDVNVDEIKNKEDILRSGDSASDSRTAYILLYE 771
GHY D D +W DD + R S + AY+L Y+
Sbjct: 1019 -YFGHYISMGRLADFDSSKTKIEWRNFDD---------STVARQSTSTLQTEDAYLLFYK 1068
>7300711 [O] KOG1868 Ubiquitin C-terminal hydrolase
Length = 888
Score = 52.8 bits (125), Expect = 2e-06
Identities = 60/224 (26%), Positives = 91/224 (39%), Gaps = 34/224 (15%)
Query: 553 TEVESSPISTIFGGQFRSVLDTPQNKESQSITYDPFQTIQLDIS-SPDVIDLESAFKKFS 611
T+ + S I +F GQ +S + + +S TY+ F + L++ + +V L +
Sbjct: 683 TKAKESMILHLFYGQMKSTVKCVACHK-ESATYESFSNLSLELPPNSNVCQLNQCMDMYF 741
Query: 612 EQESIELKS--SSGNDVEAKKHTCIDKLPQALLIQFKRFSFVSQSSKNDLSNYNSFNGRI 669
E I + S +A K I KLP L++ KRF D SN S+
Sbjct: 742 SGERIHGWNCPSCKTKRDAIKKLDISKLPPVLVVHLKRFYA-------DPSNSGSY---- 790
Query: 670 EKIRKMVKYNHELTIPKESISPNLV---STSNSEESFKYYLSGVIYHHGVSPSGGHYTCD 726
M K N+ L P E++ N + S + Y L V H+G GGHYT
Sbjct: 791 -----MKKQNY-LRFPLENLDMNPYIARAESRAVTPKTYQLYAVSNHYGTM-EGGHYTAF 843
Query: 727 VYDKDLDKWYRIDDVNVDEIKNKEDILRSGDSASDSRTAYILLY 770
+ KW++ DD V + + + S AYIL Y
Sbjct: 844 CKSANYGKWFKFDDQVVSALDSSNVV---------SSAAYILFY 878
>Hs11641425 [O] KOG1866 Ubiquitin carboxyl-terminal hydrolase
Length = 2563
Score = 52.4 bits (124), Expect = 3e-06
Identities = 53/211 (25%), Positives = 93/211 (43%), Gaps = 26/211 (12%)
Query: 560 ISTIFGGQF---RSVLDTPQNKESQSITYDPFQTIQLDISSPDVIDLESAFKKFSEQESI 616
+S + GG F + P E + + F T+ +DI + +L + +++ + + +
Sbjct: 1703 LSKVLGGSFADQKICQGCPHRYECE----ESFTTLNVDIRNHQ--NLLDSLEQYVKGDLL 1756
Query: 617 ELKSS-----SGNDVEAKKHTCIDKLPQALLIQFKRFSF-VSQSSKNDLSNYNSFNGRIE 670
E ++ V+ K I KLP L IQ KRF + + ++Y F ++
Sbjct: 1757 EGANAYHCEKCNKKVDTVKRLLIKKLPPVLAIQLKRFDYDWERECAIKFNDYFEFPRELD 1816
Query: 671 ----KIRKMVKYNHELTIPK-ESISPNLVSTSNSEESFKYYLSGVIYHHGVSPSGGHYTC 725
+ + K + P+ + I + S S + S KY L GV+ H G SGGHY
Sbjct: 1817 MEPYTVAGVAKLEGDNVNPESQLIQQSEQSESETAGSTKYRLVGVLVHSG-QASGGHYYS 1875
Query: 726 DVY-----DKDLDKWYRIDDVNVDEIKNKED 751
+ D + ++WY+ DD +V E K +D
Sbjct: 1876 YIIQRNGGDGERNRWYKFDDGDVTECKMDDD 1906
>Hs11641423 [O] KOG1866 Ubiquitin carboxyl-terminal hydrolase
Length = 2547
Score = 52.4 bits (124), Expect = 3e-06
Identities = 53/211 (25%), Positives = 93/211 (43%), Gaps = 26/211 (12%)
Query: 560 ISTIFGGQF---RSVLDTPQNKESQSITYDPFQTIQLDISSPDVIDLESAFKKFSEQESI 616
+S + GG F + P E + + F T+ +DI + +L + +++ + + +
Sbjct: 1703 LSKVLGGSFADQKICQGCPHRYECE----ESFTTLNVDIRNHQ--NLLDSLEQYVKGDLL 1756
Query: 617 ELKSS-----SGNDVEAKKHTCIDKLPQALLIQFKRFSF-VSQSSKNDLSNYNSFNGRIE 670
E ++ V+ K I KLP L IQ KRF + + ++Y F ++
Sbjct: 1757 EGANAYHCEKCNKKVDTVKRLLIKKLPPVLAIQLKRFDYDWERECAIKFNDYFEFPRELD 1816
Query: 671 ----KIRKMVKYNHELTIPK-ESISPNLVSTSNSEESFKYYLSGVIYHHGVSPSGGHYTC 725
+ + K + P+ + I + S S + S KY L GV+ H G SGGHY
Sbjct: 1817 MEPYTVAGVAKLEGDNVNPESQLIQQSEQSESETAGSTKYRLVGVLVHSG-QASGGHYYS 1875
Query: 726 DVY-----DKDLDKWYRIDDVNVDEIKNKED 751
+ D + ++WY+ DD +V E K +D
Sbjct: 1876 YIIQRNGGDGERNRWYKFDDGDVTECKMDDD 1906
>At3g11910 [O] KOG1863 Ubiquitin carboxyl-terminal hydrolase
Length = 1124
Score = 52.4 bits (124), Expect = 3e-06
Identities = 53/208 (25%), Positives = 90/208 (42%), Gaps = 31/208 (14%)
Query: 555 VESSPISTIFGGQFRSVLDTPQNKESQSITYDPFQTIQLDISSPDVIDLESAFKKFSEQE 614
V I +F G + ++ N + +S + F +QLD+ D+ ++F K+ E E
Sbjct: 309 VVEGTIQKLFEGHHMNYIECI-NVDYKSTRKESFYDLQLDVKGCK--DVYASFDKYVEVE 365
Query: 615 SIELKS---SSGNDVE-AKKHTCIDKLPQALLIQFKRFSFVSQSSKNDLSNYNSFNGRIE 670
+E + + G+D++ AKK P L +Q KRF Y+ +
Sbjct: 366 RLEGDNKYHAEGHDLQDAKKGVLFIDFPPVLQLQLKRFE------------YDFMRDTMV 413
Query: 671 KIRKMVKYNHELTIPKES---ISPNLVSTSNSEESFKYYLSGVIYHHGVSPSGGHYTCDV 727
KI ++ +L + +E +SP+ + + Y L V+ H G GGHY +
Sbjct: 414 KINDRYEFPLQLDLDREDGRYLSPDADKSVRN----LYTLHSVLVHSG-GVHGGHYYAFI 468
Query: 728 YDKDLDKWYRIDDVNVDEIKNKEDILRS 755
D+WY+ DD V KED+ R+
Sbjct: 469 RPTLSDQWYKFDDERV----TKEDVKRA 492
>YFR010w [O] KOG1872 Ubiquitin-specific protease
Length = 499
Score = 52.0 bits (123), Expect = 3e-06
Identities = 53/201 (26%), Positives = 89/201 (43%), Gaps = 35/201 (17%)
Query: 577 NKESQSITYDPFQTIQLDISSPDVIDLESAFKKFSEQESIELKSSSGNDVEAKKHTCIDK 636
NK+S+ + F QLD++ D++ E A +K ++ + N+ E
Sbjct: 324 NKKSKILRKVVFP-FQLDVA--DMLTPEYAAEKVKVRDELRKVEKEKNEKER-------- 372
Query: 637 LPQALLIQFKRFSFVSQSSKNDLSNYNSFNGRI-----EKIRKMVKYNHELTIPKESISP 691
+ KR F SS+N ++ + ++ EK + + +Y K+ P
Sbjct: 373 -------EIKRRKFDPSSSENVMTPREQYETQVALNESEKDQWLEEY-------KKHFPP 418
Query: 692 NLVSTSNSEESFKYYLSGVIYHHGVSPSGGHYTCDVYDK-DLDKWYRIDDVNVDEIKNKE 750
NL N S Y L GVI H G + GHY + D+ D +KWY+ +D V ++ ++
Sbjct: 419 NLEKGENP--SCVYNLIGVITHQGANSESGHYQAFIRDELDENKWYKFNDDKVSVVEKEK 476
Query: 751 DILRSGDSASDSRTAYILLYE 771
+G SDS A IL+Y+
Sbjct: 477 IESLAGGGESDS--ALILMYK 495
>YMR304w [O] KOG1863 Ubiquitin carboxyl-terminal hydrolase
Length = 1230
Score = 51.2 bits (121), Expect = 6e-06
Identities = 53/212 (25%), Positives = 91/212 (42%), Gaps = 37/212 (17%)
Query: 553 TEVESSPISTIFGGQFRSVLDTPQNKESQSITYDPFQTIQLDISSPDVIDLESAFKKFSE 612
T VE ++ IF G+ +S + N + +S + F +QL++ + +L+ +F + E
Sbjct: 305 TPVEGK-LNEIFVGKMKSYIKCI-NVDYESARVEDFWDLQLNVKN--FKNLQESFDNYIE 360
Query: 613 QESIELKSS-SGNDV---EAKKHTCIDKLPQALLIQFKRFSFVSQSSKNDLSNYNSFNGR 668
E + ++ + D +A+K + P L +Q KRF + NY+
Sbjct: 361 MELMNGENQYAAQDYGLQDAQKGVIFESFPPVLHLQLKRFEYDF--------NYD----- 407
Query: 669 IEKIRKMVKYNHELTIP----------KESISPNLVSTSNSEESFKYYLSGVIYHHGVSP 718
+MVK N + P K+ + L S + + + Y L GV+ H G
Sbjct: 408 -----QMVKVNDKYEFPETIDLSPFVDKDVLKKTLDSENKDKNPYVYNLHGVLVHSG-DI 461
Query: 719 SGGHYTCDVYDKDLDKWYRIDDVNVDEIKNKE 750
S GHY + D+WYR DD V + K+
Sbjct: 462 STGHYYTLIKPGVEDQWYRFDDERVWRVTKKQ 493
>SPCC1682.12c [O] KOG1865 Ubiquitin carboxyl-terminal hydrolase
Length = 457
Score = 51.2 bits (121), Expect = 6e-06
Identities = 60/232 (25%), Positives = 85/232 (35%), Gaps = 57/232 (24%)
Query: 556 ESSPISTIFGGQFR-----SVLDTPQNKESQSITYDPFQTIQLDISSPDVIDLESAF--- 607
E+S + IFGG R SV P N TY + +D + D F
Sbjct: 243 ETSVVHRIFGGYLRQQILCSVCKKPSN------TYQALLDLSVDAKGSSLADSLKHFVHA 296
Query: 608 KKFSEQESIELKSSSGNDVEAKKHTCIDKLPQALLIQFKRFSFVSQSSKNDLSNYNSFNG 667
+K ++Q ++ V+A K I + P L I FKRF+F N F
Sbjct: 297 EKLTKQNKYRCENCK-QLVDASKQMTIYRAPNILTIHFKRFTF------------NGFQS 343
Query: 668 RIEKIRKMVKYNHELTIPKESISPNLVSTSNSEESFKYYLSGVIYHHGVSPSGGHYTCDV 727
KI K + Y + PN S Y L GV+ H G S GHY
Sbjct: 344 --SKISKQISYPESFNLGPYMSDPNC--------SCWYELIGVLVHAGGSTRSGHYYSFC 393
Query: 728 YDKDLDKWYRIDD-----VNVDEIKNKEDILRSGDSASDSRTAYILLYEKSS 774
+ W + DD ++D + N++ AYIL Y++ S
Sbjct: 394 KSSN-GVWLKFDDDFVSNSSIDRVLNQQ--------------AYILQYKRKS 430
>SPCC16A11.12c [O] KOG1870 Ubiquitin C-terminal hydrolase
Length = 849
Score = 50.8 bits (120), Expect = 8e-06
Identities = 59/190 (31%), Positives = 84/190 (44%), Gaps = 31/190 (16%)
Query: 588 FQTIQLDISSPDVIDLESAFKKFSEQESIELKSS---SGNDV--EAKKHTCIDKLPQALL 642
F+ IQ + S I LE +FS+ E ++L+ S G A K I +LP+ L+
Sbjct: 680 FEKIQFHMES---ITLEDCLLEFSKPEQLDLQDSWYCPGCKAFRPATKRLEIWRLPKILV 736
Query: 643 IQFKRFSFVSQSSKNDLSNYNSFNGRIEKIRKMVKYNHELTIPKESISPNLVSTS--NSE 700
I RFS DL R K R +V Y K+ +SP + +S+
Sbjct: 737 IHLNRFS----GHGGDLR-------RRRKRRDLVVYPVFDLNLKQFLSPFIKDHEWLSSQ 785
Query: 701 ESFKYYLSGVIYHHGVSPSGGHYTCDVYDKDLDKWYRIDDVNVDEIKNKEDILRSGDSAS 760
+S Y L V HHG S GHYT D +++ DD + EI + EDI+ S
Sbjct: 786 KSMLYDLYAVDNHHGFM-SNGHYTAYARDASSQTFFKFDDTAICEI-DPEDIVTS----- 838
Query: 761 DSRTAYILLY 770
+AY+L Y
Sbjct: 839 ---SAYVLFY 845
Database: KOG eukaryal database 04/03
Posted date: Apr 14, 2003 1:07 PM
Number of letters in database: 30,389,216
Number of sequences in database: 60,738
Lambda K H
0.312 0.130 0.364
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 41,426,321
Number of Sequences: 60738
Number of extensions: 1656093
Number of successful extensions: 4614
Number of sequences better than 1.0e-05: 41
Number of HSP's better than 0.0 without gapping: 3
Number of HSP's successfully gapped in prelim test: 38
Number of HSP's that attempted gapping in prelim test: 4518
Number of HSP's gapped (non-prelim): 99
length of query: 774
length of database: 30,389,216
effective HSP length: 114
effective length of query: 660
effective length of database: 23,465,084
effective search space: 15486955440
effective search space used: 15486955440
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.9 bits)