ORF STATUS Function Best COG Functional category Pathways and functional systems
r_klactV0336 good UO KOG1373 Intracellular trafficking, secretion, and vesicular transport Transport protein Sec61, alpha subunit
r_klactV0336 good UO KOG1373 Posttranslational modification, protein turnover, chaperones Transport protein Sec61, alpha subunit
Only best alignment is shown:
BLASTP 2.2.3 [May-13-2002]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= r_klactV0336 122633 121194 -480
(480 letters)
Database: KOG eukaryal database 04/03
60,738 sequences; 30,389,216 total letters
Searching..................................................done
Color Key for Alignment Scores: 
Score E
Sequences producing significant alignments: (bits) Value
YLR378c [UO] KOG1373 Transport protein Sec61 alpha subunit 765 0.0
SPBC354.02c [UO] KOG1373 Transport protein Sec61 alpha subunit 538 e-153
Hs7019415 [UO] KOG1373 Transport protein Sec61 alpha subunit 530 e-150
Hs14589847 [UO] KOG1373 Transport protein Sec61 alpha subunit 529 e-150
CE14954 [UO] KOG1373 Transport protein Sec61 alpha subunit 513 e-145
At1g78720 [UO] KOG1373 Transport protein Sec61 alpha subunit 502 e-142
At2g34250 [UO] KOG1373 Transport protein Sec61 alpha subunit 499 e-141
At1g29310 [UO] KOG1373 Transport protein Sec61 alpha subunit 495 e-140
7297121 [UO] KOG1373 Transport protein Sec61 alpha subunit 469 e-132
ECU09g0130 [UO] KOG1373 Transport protein Sec61 alpha subunit 369 e-102
YBR283c [UO] KOG1373 Transport protein Sec61 alpha subunit 234 2e-61
SPBC19G7.17 [UO] KOG1373 Transport protein Sec61 alpha subunit 111 3e-24
Hs17449156 [UO] KOG1373 Transport protein Sec61 alpha subunit 85 2e-16
>YLR378c [UO] KOG1373 Transport protein Sec61 alpha subunit
Length = 480
Score = 765 bits (1976), Expect = 0.0
Identities = 383/479 (79%), Positives = 425/479 (87%), Gaps = 1/479 (0%)
Query: 2 SGRVLDLFKPFEAYLPEVIAPERPVPYKQKLIWTGVSLLVFLVLGQIPLYGIVSSETSDP 61
S RVLDLFKPFE++LPEVIAPER VPY QKLIWTGVSLL+FL+LGQIPLYGIVSSETSDP
Sbjct: 3 SNRVLDLFKPFESFLPEVIAPERKVPYNQKLIWTGVSLLIFLILGQIPLYGIVSSETSDP 62
Query: 62 LYWLRAMLASNRGTLMELGVSPIITSSMIFQFLQGTQLLQVNMENKQDRELYQIAQKVFA 121
LYWLRAMLASNRGTL+ELGVSPIITSSMIFQFLQGTQLLQ+ E+KQDREL+QIAQKV A
Sbjct: 63 LYWLRAMLASNRGTLLELGVSPIITSSMIFQFLQGTQLLQIRPESKQDRELFQIAQKVCA 122
Query: 122 ILLTFGQAIVVVLTGNYGKPSDLGLAISLLLIFQLIFASFTVLLLDELLSKGYGLGSGIS 181
I+L GQA+VVV+TGNYG PSDLGL I LLLIFQL+FAS V+LLDELLSKGYGLGSGIS
Sbjct: 123 IILILGQALVVVMTGNYGAPSDLGLPICLLLIFQLMFASLIVMLLDELLSKGYGLGSGIS 182
Query: 182 LFTATNIAEQITWKAFAPTTVNVGRGQEFEGAVIALFHLLAIRKDKKRALVEAFYRENLP 241
LFTATNIAEQI W+AFAPTTVN GRG+EFEGAVIA FHLLA+RKDKKRALVEAFYR NLP
Sbjct: 183 LFTATNIAEQIFWRAFAPTTVNSGRGKEFEGAVIAFFHLLAVRKDKKRALVEAFYRTNLP 242
Query: 242 NMFQVFSTIGVFLSVLYLQGFRYELPIKSTRTRGQYGSYPIKLFYTSNTPIMLQSALTSN 301
NMFQV T+ +FL VLYLQGFRYELPI+ST+ RGQ G YPIKLFYTSNTPIMLQSALTSN
Sbjct: 243 NMFQVLMTVAIFLFVLYLQGFRYELPIRSTKVRGQIGIYPIKLFYTSNTPIMLQSALTSN 302
Query: 302 IFLISQILYQRFSTNPLVKLLGVWGTRAGAPAGQQVALSGLSYYIQPPFSVTDALLDPIK 361
IFLISQIL+Q++ TNPL++L+GVWG R G G Q+ALSGL+YYIQP S+++ALLDPIK
Sbjct: 303 IFLISQILFQKYPTNPLIRLIGVWGIRPGT-QGPQMALSGLAYYIQPLMSLSEALLDPIK 361
Query: 362 TVVYVGFVLGACALFSKTWIEISGTSPRDVAKQFKDQGLTINGKRETNVYKELKKIIPTA 421
T+VY+ FVLG+CA+FSKTWIEISGTSPRD+AKQFKDQG+ INGKRET++Y+ELKKIIPTA
Sbjct: 362 TIVYITFVLGSCAVFSKTWIEISGTSPRDIAKQFKDQGMVINGKRETSIYRELKKIIPTA 421
Query: 422 AAFGGAVIGAXXXXXXXXXXXXXXXXILMATTTIYGYYEVAAKEGGFTKNLVSGFSEMM 480
AAFGGA IGA ILMATTTIYGYYE AAKEGGFTKNLV GFS++M
Sbjct: 422 AAFGGATIGALSVGSDLLGTLGSGASILMATTTIYGYYEAAAKEGGFTKNLVPGFSDLM 480
>SPBC354.02c [UO] KOG1373 Transport protein Sec61 alpha subunit
Length = 479
Score = 538 bits (1385), Expect = e-153
Identities = 275/469 (58%), Positives = 339/469 (71%), Gaps = 16/469 (3%)
Query: 4 RVLDLFKPFEAYLPEVIAPERPVPYKQKLIWTGVSLLVFLVLGQIPLYGIVSSETSDPLY 63
R LDL KPF +LPE+ APER VP+KQK++WTGV+LL+FLV+ Q+PLYGIVSS++SDPL
Sbjct: 5 RFLDLVKPFAPFLPEIAAPERKVPFKQKMLWTGVTLLIFLVMSQVPLYGIVSSDSSDPLL 64
Query: 64 WLRAMLASNRGTLMELGVSPIITSSMIFQFLQGTQLLQVNMENKQDRELYQIAQKVFAIL 123
WLR +LA+NRGTLMELG+SPI+TSSM+ Q L G+QL++VNME K DRE+YQ+ QK AI+
Sbjct: 65 WLRMILAANRGTLMELGISPIVTSSMLVQLLVGSQLIEVNMELKSDREMYQLVQKFLAII 124
Query: 124 LTFGQAIVVVLTGNYGKPSDLGLAISLLLIFQLIFASFTVLLLDELLSKGYGLGSGISLF 183
+ FGQA VLTG YG+P DLG I LLLI QL AS VLLLDELL KGYGLGSGISLF
Sbjct: 125 IAFGQATAYVLTGMYGRPQDLGAGICLLLILQLAAASLIVLLLDELLQKGYGLGSGISLF 184
Query: 184 TATNIAEQITWKAFAPTTVNVGRGQEFEGAVIALFHLLAIRKDKKRALVEAFYRE----- 238
AT E I WKAF+PTT ++ G +FEGAVI +++ +K AL +AF+R
Sbjct: 185 IATINCENIFWKAFSPTTYHIANGVQFEGAVINFVYVMFTWDNKAAALYQAFFRSGLTSS 244
Query: 239 --NLPNMFQVFSTIGVFLSVLYLQGFRYELPIKSTRTRGQYGSYPIKLFYTSNTPIMLQS 296
LPN++ F+T+ VF V+YLQ FR E+PI+S + RG ++P+KL YTSNTPIMLQS
Sbjct: 245 QIQLPNLWNFFATLLVFGVVIYLQDFRVEIPIRSQKFRGYRSTFPVKLLYTSNTPIMLQS 304
Query: 297 ALTSNIFLISQILYQRFSTNPLVKLLGVWGTRAGAPAGQQVALSGLSYYIQPPFSVTDAL 356
ALTSN+F S++L+ RFS+N LV+ LGVW +Q A SGLSYY+ PP S DAL
Sbjct: 305 ALTSNLFFASRLLFNRFSSNFLVRFLGVW---------EQTATSGLSYYLSPPASFQDAL 355
Query: 357 LDPIKTVVYVGFVLGACALFSKTWIEISGTSPRDVAKQFKDQGLTINGKRETNVYKELKK 416
+DPI T+VYV F + ACALFSK WIE+SG SPRDVAKQ K Q L + G RE ++YKELK+
Sbjct: 356 IDPIHTLVYVFFTMFACALFSKLWIEVSGASPRDVAKQLKSQQLVMAGHREGSMYKELKR 415
Query: 417 IIPTAAAFGGAVIGAXXXXXXXXXXXXXXXXILMATTTIYGYYEVAAKE 465
IIPTAA GAV+GA +L+ TTTIYGYYE KE
Sbjct: 416 IIPTAAWLSGAVVGALAVASDLLGALGSGTAVLLCTTTIYGYYEQLQKE 464
>Hs7019415 [UO] KOG1373 Transport protein Sec61 alpha subunit
Length = 476
Score = 530 bits (1366), Expect = e-150
Identities = 266/466 (57%), Positives = 339/466 (72%), Gaps = 3/466 (0%)
Query: 1 MSGRVLDLFKPFEAYLPEVIAPERPVPYKQKLIWTGVSLLVFLVLGQIPLYGIVSSETSD 60
M+ + L++ KPF LPE+ PER + +K+K++WT ++L +FLV QIPL+GI+SS+++D
Sbjct: 1 MAIKFLEVIKPFCVILPEIQKPERKIQFKEKVLWTAITLFIFLVCCQIPLFGIMSSDSAD 60
Query: 61 PLYWLRAMLASNRGTLMELGVSPIITSSMIFQFLQGTQLLQVNMENKQDRELYQIAQKVF 120
P YW+R +LASNRGTLMELG+SPI+TS +I Q L G ++++V + +DR L+ AQK+F
Sbjct: 61 PFYWMRVILASNRGTLMELGISPIVTSGLIMQLLAGAKIIEVG-DTPKDRALFNGAQKLF 119
Query: 121 AILLTFGQAIVVVLTGNYGKPSDLGLAISLLLIFQLIFASFTVLLLDELLSKGYGLGSGI 180
+++T GQ+IV V+TG YG PS++G I LL+ QL A VLLLDELL KGYGLGSGI
Sbjct: 120 GMIITIGQSIVYVMTGMYGDPSEMGAGICLLITIQLFVAGLIVLLLDELLQKGYGLGSGI 179
Query: 181 SLFTATNIAEQITWKAFAPTTVNVGRGQEFEGAVIALFHLLAIRKDKKRALVEAFYRENL 240
SLF ATNI E I WKAF+PTTVN GRG EFEGA+IALFHLLA R DK RAL EAFYR+NL
Sbjct: 180 SLFIATNICETIVWKAFSPTTVNTGRGMEFEGAIIALFHLLATRTDKVRALREAFYRQNL 239
Query: 241 PNMFQVFSTIGVFLSVLYLQGFRYELPIKSTRTRGQYGSYPIKLFYTSNTPIMLQSALTS 300
PN+ + +TI VF V+Y QGFR +LPIKS R RGQY +YPIKLFYTSN PI+LQSAL S
Sbjct: 240 PNLMNLIATIFVFAVVIYFQGFRVDLPIKSARYRGQYNTYPIKLFYTSNIPIILQSALVS 299
Query: 301 NIFLISQILYQRFSTNPLVKLLGVWG-TRAGAPAGQQVALSGLSYYIQPPFSVTDALLDP 359
N+++ISQ+L RFS N LV LLG W T +G PA + + GL YY+ PP S L DP
Sbjct: 300 NLYVISQMLSARFSGNLLVSLLGTWSDTSSGGPA-RAYPVGGLCYYLSPPESFGSVLEDP 358
Query: 360 IKTVVYVGFVLGACALFSKTWIEISGTSPRDVAKQFKDQGLTINGKRETNVYKELKKIIP 419
+ VVY+ F+LG+CA FSKTWIE+SG+S +DVAKQ K+Q + + G RET++ EL + IP
Sbjct: 359 VHAVVYIVFMLGSCAFFSKTWIEVSGSSAKDVAKQLKEQQMVMRGHRETSMVHELNRYIP 418
Query: 420 TAAAFGGAVIGAXXXXXXXXXXXXXXXXILMATTTIYGYYEVAAKE 465
TAAAFGG IGA IL+A T IY Y+E+ KE
Sbjct: 419 TAAAFGGLCIGALSVLADFLGAIGSGTGILLAVTIIYQYFEIFVKE 464
>Hs14589847 [UO] KOG1373 Transport protein Sec61 alpha subunit
Length = 476
Score = 529 bits (1362), Expect = e-150
Identities = 262/465 (56%), Positives = 337/465 (72%), Gaps = 1/465 (0%)
Query: 1 MSGRVLDLFKPFEAYLPEVIAPERPVPYKQKLIWTGVSLLVFLVLGQIPLYGIVSSETSD 60
M + L++ KPF A LPE+ PER + +++K++WT ++L +FLV QIPL+GI+SS+++D
Sbjct: 1 MGIKFLEVIKPFCAVLPEIQKPERKIQFREKVLWTAITLFIFLVCCQIPLFGIMSSDSAD 60
Query: 61 PLYWLRAMLASNRGTLMELGVSPIITSSMIFQFLQGTQLLQVNMENKQDRELYQIAQKVF 120
P YW+R +LASNRGTLMELG+SPI+TS +I Q L G ++++V + +DR L+ AQK+F
Sbjct: 61 PFYWMRVILASNRGTLMELGISPIVTSGLIMQLLAGAKIIEVG-DTPKDRALFNGAQKLF 119
Query: 121 AILLTFGQAIVVVLTGNYGKPSDLGLAISLLLIFQLIFASFTVLLLDELLSKGYGLGSGI 180
+++T GQAIV V+TG YG P+++G I LL+I QL A VLLLDELL KGYGLGSGI
Sbjct: 120 GMIITIGQAIVYVMTGMYGDPAEMGAGICLLIIIQLFVAGLIVLLLDELLQKGYGLGSGI 179
Query: 181 SLFTATNIAEQITWKAFAPTTVNVGRGQEFEGAVIALFHLLAIRKDKKRALVEAFYRENL 240
SLF ATNI E I WKAF+PTT+N GRG EFEGAVIALFHLLA R DK RAL EAFYR+NL
Sbjct: 180 SLFIATNICETIVWKAFSPTTINTGRGTEFEGAVIALFHLLATRTDKVRALREAFYRQNL 239
Query: 241 PNMFQVFSTIGVFLSVLYLQGFRYELPIKSTRTRGQYGSYPIKLFYTSNTPIMLQSALTS 300
PN+ + +T+ VF V+Y QGFR +LPIKS R RGQY SYPIKLFYTSN PI+LQSAL S
Sbjct: 240 PNLMNLIATVFVFAVVIYFQGFRVDLPIKSARYRGQYSSYPIKLFYTSNIPIILQSALVS 299
Query: 301 NIFLISQILYQRFSTNPLVKLLGVWGTRAGAPAGQQVALSGLSYYIQPPFSVTDALLDPI 360
N+++ISQ+L RFS N LV LLG W +G + + GL YY+ PP S+ DP+
Sbjct: 300 NLYVISQMLSVRFSGNFLVNLLGQWADVSGGGPARSYPVGGLCYYLSPPESMGAIFEDPV 359
Query: 361 KTVVYVGFVLGACALFSKTWIEISGTSPRDVAKQFKDQGLTINGKRETNVYKELKKIIPT 420
VVY+ F+LG+CA FSKTWIE+SG+S +DVAKQ K+Q + + G R+T++ EL + IPT
Sbjct: 360 HVVVYIIFMLGSCAFFSKTWIEVSGSSAKDVAKQLKEQQMVMRGHRDTSMVHELNRYIPT 419
Query: 421 AAAFGGAVIGAXXXXXXXXXXXXXXXXILMATTTIYGYYEVAAKE 465
AAAFGG IGA IL+A T IY Y+E+ KE
Sbjct: 420 AAAFGGLCIGALSVLADFLGAIGSGTGILLAVTIIYQYFEIFVKE 464
>CE14954 [UO] KOG1373 Transport protein Sec61 alpha subunit
Length = 473
Score = 513 bits (1320), Expect = e-145
Identities = 253/465 (54%), Positives = 331/465 (70%), Gaps = 4/465 (0%)
Query: 1 MSGRVLDLFKPFEAYLPEVIAPERPVPYKQKLIWTGVSLLVFLVLGQIPLYGIVSSETSD 60
M + L+ KPF ++PEV PER + +++K++WT ++L VFLV QIPL+GI+S++++D
Sbjct: 1 MGIKFLEFVKPFCGFVPEVSKPERKIQFREKMLWTAITLFVFLVCCQIPLFGIMSTDSAD 60
Query: 61 PLYWLRAMLASNRGTLMELGVSPIITSSMIFQFLQGTQLLQVNMENKQDRELYQIAQKVF 120
P YWLR ++ASNRGTLMELG+SPI+TS +I Q L G ++++V + +DR L+ AQK+F
Sbjct: 61 PFYWLRVIMASNRGTLMELGISPIVTSGLIMQLLAGAKIIEVG-DTPKDRALFNGAQKLF 119
Query: 121 AILLTFGQAIVVVLTGNYGKPSDLGLAISLLLIFQLIFASFTVLLLDELLSKGYGLGSGI 180
+++T GQAIV V++G YG+PS++G I LL++ QL+ A VLLLDELL KGYGLGSGI
Sbjct: 120 GMVITVGQAIVYVMSGLYGEPSEIGAGICLLIVVQLVIAGLIVLLLDELLQKGYGLGSGI 179
Query: 181 SLFTATNIAEQITWKAFAPTTVNVGRGQEFEGAVIALFHLLAIRKDKKRALVEAFYRENL 240
SLF ATNI E I WKAF+P T+N GRG EFEGAVIALFHLLA R DK RAL EAFYR+NL
Sbjct: 180 SLFIATNICETIVWKAFSPATMNTGRGTEFEGAVIALFHLLATRSDKVRALREAFYRQNL 239
Query: 241 PNMFQVFSTIGVFLSVLYLQGFRYELPIKSTRTRGQYGSYPIKLFYTSNTPIMLQSALTS 300
PN+ + +T VF V+Y QGFR +LPIKS R RGQY SYPIKLFYTSN PI+LQSAL S
Sbjct: 240 PNLMNLMATFLVFAVVIYFQGFRVDLPIKSARYRGQYSSYPIKLFYTSNIPIILQSALVS 299
Query: 301 NIFLISQILYQRFSTNPLVKLLGVWGTRAGAPAGQQVALSGLSYYIQPPFSVTDALLDPI 360
N+++ISQ+L +F N + LLG W G + GL YY+ PP S+ DPI
Sbjct: 300 NLYVISQMLAGKFGGNFFINLLGTWSDNTGY---RSYPTGGLCYYLSPPESLGHIFEDPI 356
Query: 361 KTVVYVGFVLGACALFSKTWIEISGTSPRDVAKQFKDQGLTINGKRETNVYKELKKIIPT 420
++Y+ F+LG+CA FSKTWI++SG+S +DVAKQ K+Q + + G RE ++ EL + IPT
Sbjct: 357 HCIIYIVFMLGSCAFFSKTWIDVSGSSAKDVAKQLKEQQMVMRGHREKSMIHELNRYIPT 416
Query: 421 AAAFGGAVIGAXXXXXXXXXXXXXXXXILMATTTIYGYYEVAAKE 465
AAAFGG IGA IL+A T IY Y+E+ KE
Sbjct: 417 AAAFGGLCIGALSVTADFMGAIGSGTGILLAVTIIYQYFEIFVKE 461
>At1g78720 [UO] KOG1373 Transport protein Sec61 alpha subunit
Length = 475
Score = 502 bits (1292), Expect = e-142
Identities = 247/462 (53%), Positives = 332/462 (71%), Gaps = 2/462 (0%)
Query: 4 RVLDLFKPFEAYLPEVIAPERPVPYKQKLIWTGVSLLVFLVLGQIPLYGIVSSETSDPLY 63
RV+ L +PF A+LPEV +PER +P+++K+I+T +SL +FLV Q+PLYGI S+ +DP Y
Sbjct: 6 RVIHLVRPFLAFLPEVQSPERKIPFREKVIYTVISLFIFLVCSQLPLYGIHSTTGADPFY 65
Query: 64 WLRAMLASNRGTLMELGVSPIITSSMIFQFLQGTQLLQVNMENKQDRELYQIAQKVFAIL 123
W+R +LAS+RGT+MELG++PI+TS M+ Q L G+++++++ ++DR L AQK+ IL
Sbjct: 66 WMRVILASSRGTVMELGITPIVTSGMVMQLLAGSKIIEIDNNVREDRALLNGAQKLLGIL 125
Query: 124 LTFGQAIVVVLTGNYGKPSDLGLAISLLLIFQLIFASFTVLLLDELLSKGYGLGSGISLF 183
+ GQA+ VL+G YG +LG+ ++L+I QL FA+ VL LDELL KGYGLGSGISLF
Sbjct: 126 IAVGQAVAYVLSGMYGSVGELGVGNAILIIVQLCFAAIIVLCLDELLQKGYGLGSGISLF 185
Query: 184 TATNIAEQITWKAFAPTTVNVGRGQEFEGAVIALFHLLAIRKDKKRALVEAFYRENLPNM 243
ATNI E I WKAF+PTT+N GRG +FEGAVIALFHLL R DK RAL EAF+R+NLPN+
Sbjct: 186 IATNICESIIWKAFSPTTINSGRGAQFEGAVIALFHLLITRTDKVRALREAFFRQNLPNV 245
Query: 244 FQVFSTIGVFLSVLYLQGFRYELPIKSTRTRGQYGSYPIKLFYTSNTPIMLQSALTSNIF 303
+ +T+ +FL V+Y QGFR LP++S RGQ GSYPIKLFYTSN PI+LQSAL SNI+
Sbjct: 246 TNLHATVLIFLIVIYFQGFRVVLPVRSKNARGQRGSYPIKLFYTSNMPIILQSALVSNIY 305
Query: 304 LISQILYQRFSTNPLVKLLGVWGTRAGAPAGQQVALSGLSYYIQPPFSVTDALLDPIKTV 363
ISQILY++F N LV L+G W + +GQ + + G++YYI P S+ + P +
Sbjct: 306 FISQILYRKFGGNFLVNLIGTW--KESEYSGQSIPVGGIAYYITAPSSLAEMATHPFHAL 363
Query: 364 VYVGFVLGACALFSKTWIEISGTSPRDVAKQFKDQGLTINGKRETNVYKELKKIIPTAAA 423
Y+ F+L ACALFSKTWIE+SG+S +DVA+Q ++Q + + G R++N+ KEL + IPTAAA
Sbjct: 364 FYLVFMLAACALFSKTWIEVSGSSAKDVARQLREQQMVMPGHRDSNLQKELNRYIPTAAA 423
Query: 424 FGGAVIGAXXXXXXXXXXXXXXXXILMATTTIYGYYEVAAKE 465
FGG IGA IL+A T IY Y+E KE
Sbjct: 424 FGGLCIGALTVLADLMGAIGSGTGILLAVTIIYQYFETFEKE 465
>At2g34250 [UO] KOG1373 Transport protein Sec61 alpha subunit
Length = 475
Score = 499 bits (1284), Expect = e-141
Identities = 248/462 (53%), Positives = 328/462 (70%), Gaps = 2/462 (0%)
Query: 4 RVLDLFKPFEAYLPEVIAPERPVPYKQKLIWTGVSLLVFLVLGQIPLYGIVSSETSDPLY 63
RVL L +PF A+LPEV + +R VP+++K+I+T +SL +FLV Q+PLYGI S+ +DP Y
Sbjct: 6 RVLHLVRPFLAFLPEVQSADRKVPFREKVIYTVISLFIFLVCSQLPLYGIHSTTGADPFY 65
Query: 64 WLRAMLASNRGTLMELGVSPIITSSMIFQFLQGTQLLQVNMENKQDRELYQIAQKVFAIL 123
W+R +LASNRGT+MELG++PI+TS ++ Q L G+++++V+ ++DR L AQK+ IL
Sbjct: 66 WMRVILASNRGTVMELGITPIVTSGLVMQLLAGSKIIEVDNNVREDRALLNGAQKLLGIL 125
Query: 124 LTFGQAIVVVLTGNYGKPSDLGLAISLLLIFQLIFASFTVLLLDELLSKGYGLGSGISLF 183
+ G+A+ VL+G YG LG+ ++L+I QL FA V+ LDELL KGYGLGSGISLF
Sbjct: 126 IAIGEAVAYVLSGMYGPVGQLGVGNAILIILQLFFAGIIVICLDELLQKGYGLGSGISLF 185
Query: 184 TATNIAEQITWKAFAPTTVNVGRGQEFEGAVIALFHLLAIRKDKKRALVEAFYRENLPNM 243
ATNI E I WKAF+PTT+N GRG EFEGAVIALFH+L + +K AL +AFYR+NLPN+
Sbjct: 186 IATNICESIIWKAFSPTTINTGRGAEFEGAVIALFHMLITKSNKVAALRQAFYRQNLPNV 245
Query: 244 FQVFSTIGVFLSVLYLQGFRYELPIKSTRTRGQYGSYPIKLFYTSNTPIMLQSALTSNIF 303
+ +T+ +FL V+Y QGFR LP++S RGQ GSYPIKLFYTSN PI+LQSAL SN++
Sbjct: 246 TNLLATVLIFLIVIYFQGFRVVLPVRSKNARGQQGSYPIKLFYTSNMPIILQSALVSNLY 305
Query: 304 LISQILYQRFSTNPLVKLLGVWGTRAGAPAGQQVALSGLSYYIQPPFSVTDALLDPIKTV 363
ISQ+LY++FS N V LLG W + +GQ + +SGL+Y I P S +D P +
Sbjct: 306 FISQLLYRKFSGNFFVNLLGQW--KESEYSGQSIPVSGLAYLITAPASFSDMAAHPFHAL 363
Query: 364 VYVGFVLGACALFSKTWIEISGTSPRDVAKQFKDQGLTINGKRETNVYKELKKIIPTAAA 423
Y+ F+L ACALFSKTWIE+SG+S RDVAKQ K+Q + + G RE+N+ KEL + IPTAAA
Sbjct: 364 FYIVFMLTACALFSKTWIEVSGSSARDVAKQLKEQQMVMPGHRESNLQKELNRYIPTAAA 423
Query: 424 FGGAVIGAXXXXXXXXXXXXXXXXILMATTTIYGYYEVAAKE 465
FGG IGA IL+A T IY Y+E KE
Sbjct: 424 FGGVCIGALTVLADFMGAIGSGTGILLAVTIIYQYFETFEKE 465
>At1g29310 [UO] KOG1373 Transport protein Sec61 alpha subunit
Length = 475
Score = 495 bits (1274), Expect = e-140
Identities = 247/462 (53%), Positives = 326/462 (70%), Gaps = 2/462 (0%)
Query: 4 RVLDLFKPFEAYLPEVIAPERPVPYKQKLIWTGVSLLVFLVLGQIPLYGIVSSETSDPLY 63
RVL L +PF A+LPEV + +R +P+++K+I+T +SL +FLV Q+PLYGI S+ +DP Y
Sbjct: 6 RVLHLVRPFLAFLPEVQSADRKIPFREKVIYTVISLFIFLVCSQLPLYGIHSTTGADPFY 65
Query: 64 WLRAMLASNRGTLMELGVSPIITSSMIFQFLQGTQLLQVNMENKQDRELYQIAQKVFAIL 123
W+R +LASNRGT+MELG++PI+TS ++ Q L G+++++V+ ++DR L AQK+ IL
Sbjct: 66 WMRVILASNRGTVMELGITPIVTSGLVMQLLAGSKIIEVDNNVREDRALLNGAQKLLWIL 125
Query: 124 LTFGQAIVVVLTGNYGKPSDLGLAISLLLIFQLIFASFTVLLLDELLSKGYGLGSGISLF 183
G+A+ VL+G YG LG+ ++L+I QL FA V+ LDELL KGYGLGSGISLF
Sbjct: 126 SAIGEAVAYVLSGMYGPVGQLGVGNAILIILQLFFAGIIVICLDELLQKGYGLGSGISLF 185
Query: 184 TATNIAEQITWKAFAPTTVNVGRGQEFEGAVIALFHLLAIRKDKKRALVEAFYRENLPNM 243
ATNI E I WKAF+PTT+N GRG EFEGAVIALFH+L + +K AL +AFYR+NLPN+
Sbjct: 186 IATNICESIIWKAFSPTTINTGRGAEFEGAVIALFHMLITKSNKVAALRQAFYRQNLPNV 245
Query: 244 FQVFSTIGVFLSVLYLQGFRYELPIKSTRTRGQYGSYPIKLFYTSNTPIMLQSALTSNIF 303
+ +T+ +FL V+Y QGFR LP++S RGQ GSYPIKLFYTSN PI+LQSAL SN++
Sbjct: 246 TNLLATVLIFLIVIYFQGFRVVLPVRSKSARGQQGSYPIKLFYTSNMPIILQSALVSNLY 305
Query: 304 LISQILYQRFSTNPLVKLLGVWGTRAGAPAGQQVALSGLSYYIQPPFSVTDALLDPIKTV 363
ISQ+LY++FS N V LLG W + +GQ + +SGL+Y I P S D P +
Sbjct: 306 FISQLLYRKFSGNFFVNLLGQW--KESEYSGQSIPVSGLAYLITAPASFADMAAHPFHAL 363
Query: 364 VYVGFVLGACALFSKTWIEISGTSPRDVAKQFKDQGLTINGKRETNVYKELKKIIPTAAA 423
Y+ F+L ACALFSKTWIE+SG+S RDVAKQ K+Q + + G RE+N+ KEL + IPTAAA
Sbjct: 364 FYIVFMLTACALFSKTWIEVSGSSARDVAKQLKEQQMVMPGHRESNLQKELNRYIPTAAA 423
Query: 424 FGGAVIGAXXXXXXXXXXXXXXXXILMATTTIYGYYEVAAKE 465
FGG IGA IL+A T IY Y+E KE
Sbjct: 424 FGGVCIGALTVLADFMGAIGSGTGILLAVTIIYQYFETFEKE 465
>7297121 [UO] KOG1373 Transport protein Sec61 alpha subunit
Length = 423
Score = 469 bits (1206), Expect = e-132
Identities = 233/412 (56%), Positives = 295/412 (71%), Gaps = 1/412 (0%)
Query: 54 VSSETSDPLYWLRAMLASNRGTLMELGVSPIITSSMIFQFLQGTQLLQVNMENKQDRELY 113
+SS+++DP YW+R +LASNRGTLMELG+SPI+TS +I Q L G ++++V + +DR L+
Sbjct: 1 MSSDSADPFYWIRVILASNRGTLMELGISPIVTSGLIMQLLAGAKIIEVG-DTPKDRALF 59
Query: 114 QIAQKVFAILLTFGQAIVVVLTGNYGKPSDLGLAISLLLIFQLIFASFTVLLLDELLSKG 173
AQK+F +++T GQAIV V+TG YG PS++G + LL+I QL A VLLLDELL KG
Sbjct: 60 NGAQKLFGMVITIGQAIVYVMTGMYGDPSEIGAGVCLLIIIQLFAAGLIVLLLDELLQKG 119
Query: 174 YGLGSGISLFTATNIAEQITWKAFAPTTVNVGRGQEFEGAVIALFHLLAIRKDKKRALVE 233
YGLGSGISLF ATNI E I WKAF+PTTV GRG EFEGAVIALFHL+A R DK RAL E
Sbjct: 120 YGLGSGISLFIATNICETIVWKAFSPTTVTTGRGTEFEGAVIALFHLMATRNDKVRALRE 179
Query: 234 AFYRENLPNMFQVFSTIGVFLSVLYLQGFRYELPIKSTRTRGQYGSYPIKLFYTSNTPIM 293
AFYR+NLPN+ + +T+ VF V+Y QGFR +LPIKS R RGQY SYPIKLFYTSN PI+
Sbjct: 180 AFYRQNLPNLMNLLATVLVFAVVIYFQGFRVDLPIKSARYRGQYSSYPIKLFYTSNIPII 239
Query: 294 LQSALTSNIFLISQILYQRFSTNPLVKLLGVWGTRAGAPAGQQVALSGLSYYIQPPFSVT 353
LQSAL SN+++ISQ+L +F N + LLGVW G + + GL YY+ PP SV
Sbjct: 240 LQSALVSNLYVISQMLAVKFQGNFFINLLGVWADVGGGGPARSYPIGGLCYYLSPPESVG 299
Query: 354 DALLDPIKTVVYVGFVLGACALFSKTWIEISGTSPRDVAKQFKDQGLTINGKRETNVYKE 413
L DPI ++Y+ F+LG+CA FSKTWI++SG+S +DVAKQ K+Q + + G RE ++ E
Sbjct: 300 HILTDPIHALLYIVFMLGSCAFFSKTWIDVSGSSAKDVAKQLKEQHMVMRGHRENSMIHE 359
Query: 414 LKKIIPTAAAFGGAVIGAXXXXXXXXXXXXXXXXILMATTTIYGYYEVAAKE 465
L + IPTAAAFGG IGA IL+A T IY Y+E+ KE
Sbjct: 360 LNRYIPTAAAFGGLCIGALSVMADFLGAIGSGTGILLAVTIIYQYFEIFVKE 411
>ECU09g0130 [UO] KOG1373 Transport protein Sec61 alpha subunit
Length = 410
Score = 369 bits (948), Expect = e-102
Identities = 187/414 (45%), Positives = 268/414 (64%), Gaps = 4/414 (0%)
Query: 65 LRAMLASNRGTLMELGVSPIITSSMIFQFLQGTQLLQVNMENKQDRELYQIAQKVFAILL 124
+RAM+ASNRGTLM+LG SP++TSS+I QFL +++L+V+ K+D+ L+ Q++ ++++
Sbjct: 1 MRAMMASNRGTLMDLGTSPVVTSSLIMQFLTMSEILKVDWSIKEDKNLHNATQRLISLIM 60
Query: 125 TFGQAIVVVLTGNYGKPSDLGLAISLLLIFQLIFASFTVLLLDELLSKGYGLGSGISLFT 184
T GQA+V V TG YG P LG LLL+ QLIF+ ++LLDELL KGYGLG+G++LF
Sbjct: 61 TVGQALVQVYTGFYGSPKSLGTIYCLLLVVQLIFSGIIIILLDELLQKGYGLGNGVNLFI 120
Query: 185 ATNIAEQITWKAFAPTTVNVGRGQEFEGAVIALFHLLAIRKDKKRALVEAFYRENLPNMF 244
A N+ E I WKAF+P + GRG EFEG+VIALFHLL +RK+K A+ EAF+R+NLPN+F
Sbjct: 121 AANVCESIIWKAFSPKVLFTGRGIEFEGSVIALFHLLVVRKNKFAAIYEAFFRQNLPNLF 180
Query: 245 QVFSTIGVFLSVLYLQGFRYELPIKSTRTRGQYGSYPIKLFYTSNTPIMLQSALTSNIFL 304
+ STI +F+ V+YLQG R ELP +S++ RG G +PIKL YTS PI+ QS + +I
Sbjct: 181 SLLSTILLFVFVIYLQGMRVELPTESSQVRGHVGKFPIKLLYTSTMPIIAQSYIVGHISS 240
Query: 305 ISQILYQRFSTNPLVKLLGVWGTRAGAPAGQQVALSGLSYYIQPPFSVTDALLDPIKTVV 364
IS LY+R+ +V++LGVW T G G+ + +SG+SYYI P S+ + DP++ V+
Sbjct: 241 ISSFLYKRWPQYLVVRILGVWNTSKG---GRYMPVSGVSYYITSPESIFEGFRDPLRFVI 297
Query: 365 YVGFVLGACALFSKTWIEISGTSPRDVAKQFKDQGLTINGKRETNVYKELKKIIPTAAAF 424
Y+ + A+ S +W+E++ SP A++ K+ + + G RE N L + IPTAA
Sbjct: 298 YLAIMFLTSAILSTSWLELNELSPEKAAQKLKESRMRLKGVREANTANVLSRYIPTAAFL 357
Query: 425 GGAVIGAXXXXXXXXXXXXXXXXILMATTTIYGYYEVAAKEGGFTKNLVSGFSE 478
GG + I +AT+ + Y E+ AKE KN GF E
Sbjct: 358 GGMLTSMVVIMSNLFDTIGSGTNIFLATSIVSQYLEMFAKE-SMQKNSEIGFIE 410
>YBR283c [UO] KOG1373 Transport protein Sec61 alpha subunit
Length = 490
Score = 234 bits (598), Expect = 2e-61
Identities = 154/441 (34%), Positives = 234/441 (52%), Gaps = 19/441 (4%)
Query: 1 MSG-RVLDLFKPFEAYLPEVIAPERPVPYKQKLIWTGVSLLVFLVLGQIPLYGIVSSET- 58
MSG R++D+ KP LPEV P +P+ K+++T + L++L Q PL G+ + T
Sbjct: 1 MSGFRLIDIVKPILPILPEVELPFEKLPFDDKIVYTIFAGLIYL-FAQFPLVGLPKATTP 59
Query: 59 --SDPLYWLRAMLASNRGTLMELGVSPIITSSMIFQFLQGTQLLQVNMENKQDRELYQIA 116
+DP+Y+LR + TL+E G+ P I+S +I Q L G ++++VN + + DREL+Q
Sbjct: 60 NVNDPIYFLRGVFGCEPRTLLEFGLFPNISSGLILQLLAGLKVIKVNFKIQSDRELFQSL 119
Query: 117 QKVFAILLTFGQAIVVVLTGNYGKPSDLGLAISLLLIFQLIFASFTVLLLDELLSKGYGL 176
KVFAI+ + + G +G DL + L+ FQL+ A LL E++ KG+G
Sbjct: 120 TKVFAIVQYVILTNIFIFAGYFG--DDLSVVQIGLINFQLVGAGIFTTLLAEVIDKGFGF 177
Query: 177 GSGISLFTATNIAEQITWKAFAPTTVNVGRGQEFE--GAVIALFH-LLAIRKDKKRALVE 233
SG + IA + F + + VG + E GA+I L L + K ++
Sbjct: 178 SSGAMIINTVVIATNLVADTFGVSQIKVGEDDQTEAQGALINLIQGLRSKHKTFIGGIIS 237
Query: 234 AFYRENLPNMFQVFSTIGVFLSVLYLQGFRYELPIKSTRTRGQYGSYPIKLFYTSNTPIM 293
AF R+ LPN+ + + + V YLQ R ELPI+STR RG YPIKL YT ++
Sbjct: 238 AFNRDYLPNLTTTIIVLAIAIIVCYLQSVRVELPIRSTRARGTNNVYPIKLLYTGCLSVL 297
Query: 294 LQSALTSNI----FLISQILYQRFSTNPLVKLLGVWGTRAGAPAGQQVALSGLSYYIQPP 349
+ I F++ Q++ + T+ + K++G + A LS L+ PP
Sbjct: 298 FSYTILFYIHIFAFVLIQLVAKNEPTHIICKIMGHYENANNLLAVPTFPLSLLA----PP 353
Query: 350 FSVTDALLD-PIKTVVYVGFVLGACALFSKTWIEISGTSPRDVAKQFKDQGLTINGKRET 408
S + P+ + Y F+L F+ W ISG+S RDVA +FKDQG+T+ G+RE
Sbjct: 354 TSFFKGVTQQPLTFITYSAFILVTGIWFADKWQAISGSSARDVALEFKDQGITLMGRREQ 413
Query: 409 NVYKELKKIIPTAAAFGGAVI 429
NV KEL K+IP AA G +V+
Sbjct: 414 NVAKELNKVIPIAAVTGASVL 434
>SPBC19G7.17 [UO] KOG1373 Transport protein Sec61 alpha subunit
Length = 179
Score = 111 bits (277), Expect = 3e-24
Identities = 63/175 (36%), Positives = 96/175 (54%)
Query: 4 RVLDLFKPFEAYLPEVIAPERPVPYKQKLIWTGVSLLVFLVLGQIPLYGIVSSETSDPLY 63
R ++ KP + LPEV P+ + +KL W ++V+ +L IP+YG ++T DP+
Sbjct: 5 RFINFIKPLSSLLPEVEGPKTHLELVEKLGWMAGCVVVYQILSIIPVYGAEKTDTLDPIN 64
Query: 64 WLRAMLASNRGTLMELGVSPIITSSMIFQFLQGTQLLQVNMENKQDRELYQIAQKVFAIL 123
R + S+ LM G++PI SS + Q L + + VN DR L+Q AQKV + L
Sbjct: 65 NFRVLDGSSASGLMITGLAPIYLSSFLLQILASKKKIAVNFNLIIDRVLFQNAQKVVSAL 124
Query: 124 LTFGQAIVVVLTGNYGKPSDLGLAISLLLIFQLIFASFTVLLLDELLSKGYGLGS 178
L A+ V +G YG SDLG+ ++LI Q+ + L E++ KG+GLGS
Sbjct: 125 LYLILAVTYVSSGYYGSFSDLGIFRFIMLILQIFLPGIVCIYLCEIIEKGHGLGS 179
>Hs17449156 [UO] KOG1373 Transport protein Sec61 alpha subunit
Length = 114
Score = 85.1 bits (209), Expect = 2e-16
Identities = 43/86 (50%), Positives = 62/86 (72%), Gaps = 3/86 (3%)
Query: 47 QIPLYGIVSSETSDPLYWLRAMLASNRGTLM--ELGVSPIITSSMIFQFLQGTQLLQVNM 104
QIPL+GI+SS++ DP YW+R +LASNRGTLM ELG+SPI+ S +I Q L G ++++V
Sbjct: 28 QIPLFGIMSSDSVDPFYWMRVILASNRGTLMELELGISPIVMSGLIMQLLAGAKIIEVGG 87
Query: 105 ENKQDRELYQIAQKVFAILLTFGQAI 130
K D+ L AQK+ +++T GQ +
Sbjct: 88 TPK-DQVLINEAQKLLHMIITIGQLL 112
Database: KOG eukaryal database 04/03
Posted date: Apr 14, 2003 1:07 PM
Number of letters in database: 30,389,216
Number of sequences in database: 60,738
Lambda K H
0.323 0.140 0.402
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 25,350,048
Number of Sequences: 60738
Number of extensions: 1000562
Number of successful extensions: 2082
Number of sequences better than 1.0e-05: 13
Number of HSP's better than 0.0 without gapping: 13
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 2049
Number of HSP's gapped (non-prelim): 13
length of query: 480
length of database: 30,389,216
effective HSP length: 110
effective length of query: 370
effective length of database: 23,708,036
effective search space: 8771973320
effective search space used: 8771973320
T: 11
A: 40
X1: 16 ( 7.5 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.9 bits)