ORF STATUS Function Best COG Functional category Pathways and functional systems
r_klactV0363 good R KOG0118 General function prediction only FOG: RRM domain
Only best alignment is shown:
BLASTP 2.2.3 [May-13-2002]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= r_klactV0363 129929 130726 266
(266 letters)
Database: KOG eukaryal database 04/03
60,738 sequences; 30,389,216 total letters
Searching..................................................done
Color Key for Alignment Scores: 
Score E
Sequences producing significant alignments: (bits) Value
YDL051w [R] KOG0118 FOG: RRM domain 219 4e-57
SPAC57A10.10c [R] KOG0118 FOG: RRM domain 114 1e-25
At5g46250 [R] KOG1855 Predicted RNA-binding protein 76 4e-14
ECU09g0680 [R] KOG0118 FOG: RRM domain 76 6e-14
At4g32720 [R] KOG0118 FOG: RRM domain 75 1e-13
CE08718 [A] KOG4213 RNA-binding protein La 73 5e-13
Hs10835067 [A] KOG4213 RNA-binding protein La 65 8e-11
At2g43970 [R] KOG1855 Predicted RNA-binding protein 59 7e-09
At1g79880 [R] KOG0118 FOG: RRM domain 59 7e-09
7298671 [A] KOG4213 RNA-binding protein La 57 4e-08
Hs22043788_2 [A] KOG4213 RNA-binding protein La 55 1e-07
CE28950 [OJ] KOG2590 RNA-binding protein LARP/SRO9 and related L... 54 2e-07
CE28663 [T] KOG2591 c-Mpl binding protein contains La domain 54 2e-07
7291035 [R] KOG0118 FOG: RRM domain 54 3e-07
7301667 [OJ] KOG2590 RNA-binding protein LARP/SRO9 and related L... 50 3e-06
Hs22049862 [OJ] KOG2590 RNA-binding protein LARP/SRO9 and relate... 50 4e-06
>YDL051w [R] KOG0118 FOG: RRM domain
Length = 275
Score = 219 bits (557), Expect = 4e-57
Identities = 119/256 (46%), Positives = 160/256 (62%), Gaps = 16/256 (6%)
Query: 9 RRGSYAPIDFTPEVSQACRKQVEFYFSEYNLPYDKFLRSLCEQNDGWIPITTLASFNRMK 68
RR S+A I+FTPEV C KQVEFYFSE+N PYD+FLR+ E+NDGW+PI+T+A+FNRMK
Sbjct: 16 RRNSFAVIEFTPEVLDRCLKQVEFYFSEFNFPYDRFLRTTAEKNDGWVPISTIATFNRMK 75
Query: 69 KYRPVDKVVDCLKDSTILEVSADGENVRRKSPLETVDFK----DRNERVLVFMNFKKIEN 124
KYRPVDKV++ L+ S ILEVSADGENV+R+ PL+ + ++N+R L MNF E+
Sbjct: 76 KYRPVDKVIEALRSSEILEVSADGENVKRRVPLDLTAARNARIEQNQRTLAVMNFPH-ED 134
Query: 125 XXXXXXXXXXXXXXXXXNGFTTVNQVRLKKDHK-KYFNGVVEVEFKTKEECVKFFEEHKT 183
+NQVRL++DH+ K FNG V VEFKT EC F + +
Sbjct: 135 VEASQIPELQENLEAFFKKLGEINQVRLRRDHRNKKFNGTVLVEFKTIPECEAFLKSYSN 194
Query: 184 D------FSYQGQPLEVVTKKQYSLAKNATRSKNFGGSGQKTRSLTGY-RKNIPKTNDET 236
D SY+G+ L V+TKKQ+ L + A++SKNF G ++RS G+ +KN+PK
Sbjct: 195 DDESNEILSYEGKKLSVLTKKQFDLQREASKSKNFSG---RSRSFNGHKKKNLPKFPKNK 251
Query: 237 PEASSESKLSEGDANA 252
+ E + A A
Sbjct: 252 KKNGKEESKEDSSAIA 267
>SPAC57A10.10c [R] KOG0118 FOG: RRM domain
Length = 298
Score = 114 bits (286), Expect = 1e-25
Identities = 78/236 (33%), Positives = 119/236 (50%), Gaps = 27/236 (11%)
Query: 28 KQVEFYFSEYNLPYDKFLRSLCEQNDGWIPITTLASFNRMKKYRPVDKVVDCLKDS-TIL 86
KQVEFYFS+ NLP+DKFL + ++NDGW+PI T+A+F RM++++P++ +V+ L+ S +L
Sbjct: 69 KQVEFYFSDTNLPHDKFLWTTSQKNDGWVPIQTIANFKRMRRFQPLEAIVNALRKSPELL 128
Query: 87 EVSADGENVRRKSPLETVDFKDRNERVLVFMNFKKIENXXXXXXXXXXXXXXXXXNGFTT 146
EV GE VRR PL VD K ER + F ++
Sbjct: 129 EVDEAGEKVRRMIPLVRVDNKSVMERSVYCKGFGDEKDDTQIALEKFFEENAG------P 182
Query: 147 VNQVRLKKDHKKYFNGVVEVEFKTKEECVKFFEEHKT-DFSYQGQPLEVVTKKQY----- 200
++ VR+++D K F G V VEFK + KF E+ KT + L +++KK+Y
Sbjct: 183 ISAVRMRRDDDKKFKGSVFVEFKEPDVANKFLEKVKTAPLKWGEDELTIMSKKEYVDMKA 242
Query: 201 SLAKN-----ATRSKNFGGSGQKTRSLTGYRKN---------IPKTNDETPEASSE 242
L KN +++ + F + R G N ++E P A+SE
Sbjct: 243 ELHKNDPPKFSSKRRRFDAFKEMDRQRPGKYSNRGRKFKKQRSSNASEEKPSAASE 298
>At5g46250 [R] KOG1855 Predicted RNA-binding protein
Length = 411
Score = 76.3 bits (186), Expect = 4e-14
Identities = 44/96 (45%), Positives = 65/96 (66%), Gaps = 5/96 (5%)
Query: 11 GSYAPIDFTPEVSQACRKQVEFYFSEYNLPYDKFLRSLCEQN-DGWIPITTLASFNRMKK 69
G PID E++Q +QVE+YFS+ NLP DKFL + ++N G++PI+T+A+F++MKK
Sbjct: 84 GVVVPID---ELNQKIIRQVEYYFSDENLPTDKFLLNAMKRNKKGFVPISTIATFHKMKK 140
Query: 70 Y-RPVDKVVDCLKDSTILEVSADGENVRRKSPLETV 104
R +V LK+S+ L VSAD + V+R SPL +
Sbjct: 141 LTRDHALIVSALKESSFLVVSADEKKVKRLSPLPEI 176
>ECU09g0680 [R] KOG0118 FOG: RRM domain
Length = 296
Score = 75.9 bits (185), Expect = 6e-14
Identities = 51/156 (32%), Positives = 79/156 (49%), Gaps = 11/156 (7%)
Query: 27 RKQVEFYFSEYNLPYDKFLRSLCEQNDGWIPITTLASFNRMKKY-RPVDKVVDCLKDSTI 85
+ QVEFYFS+ N DKFL+ N+G+IPI T+ SFNR+K VD V + LKDS +
Sbjct: 10 KSQVEFYFSDANFRVDKFLKEQSLVNNGYIPIKTVVSFNRLKGLGATVDDVKEALKDSRV 69
Query: 86 LEVSAD-GENVRRKSPLETVDFKDRNERVLVFMNFKKIENXXXXXXXXXXXXXXXXXNGF 144
+E+ D + V + L + KD ++RV+ F + +
Sbjct: 70 VEIKDDMVKKVETEEYLSYLMEKDISKRVVYISGFDR---------NSTLEDIKEMVSPH 120
Query: 145 TTVNQVRLKKDHKKYFNGVVEVEFKTKEECVKFFEE 180
T +R+++D +K F+G V E K++EE + E
Sbjct: 121 ITPVLIRMRRDKEKNFSGSVFAEMKSEEEAQRALSE 156
>At4g32720 [R] KOG0118 FOG: RRM domain
Length = 483
Score = 74.7 bits (182), Expect = 1e-13
Identities = 69/270 (25%), Positives = 117/270 (42%), Gaps = 44/270 (16%)
Query: 19 TPEVSQACRKQVEFYFSEYNLPYDKFL-RSLCEQNDGWIPITTLASFNRMKKY------- 70
T E ++ +QVEFYFS+ NLP D FL +++ E DG + + + SF++M+ Y
Sbjct: 7 TEETAKTVLRQVEFYFSDSNLPIDDFLKKTVTESEDGLVSLALICSFSKMRGYLKLGDSK 66
Query: 71 ------RPVDKVVDCLKDSTILEVSADGENVRRKSPLETVD--FKDRNERVLVFMNF--- 119
+ V D L+ S+ L++S DG+ V R + L ++ + N R + F
Sbjct: 67 GDDIPEDTIKAVADTLRTSSALKISDDGKKVGRSTELLKLEDLIEQLNARTVAASPFSYD 126
Query: 120 ---KKIENXXXXXXXXXXXXXXXXXNGFTTVNQVRLKKD--HKKYFNGVVEVEFKTKEEC 174
+ +E+ VN VR+ + + F+GV VEF T+E+
Sbjct: 127 VKREDVESFFSQYGKIGYTSFWYMYVSSLQVNSVRMPRHVAESRIFSGVALVEFPTEEDA 186
Query: 175 VKFFEEHKTDFSYQGQPLEVVTKKQY--SLAKNATRSKNF----GGSGQKT----RSLTG 224
K + + GQ LE+ KK++ K+ + N+ G + QK ++ +
Sbjct: 187 QNVM---KQNLVFAGQELELKPKKEFDNEREKDEVKFANYQPQKGSANQKNGSDHKNNSA 243
Query: 225 YRKNIPK-------TNDETPEASSESKLSE 247
Y + PK E ++E K SE
Sbjct: 244 YEPDYPKGLIISFTLKRSAEEGTTEQKSSE 273
>CE08718 [A] KOG4213 RNA-binding protein La
Length = 396
Score = 72.8 bits (177), Expect = 5e-13
Identities = 51/179 (28%), Positives = 84/179 (46%), Gaps = 24/179 (13%)
Query: 21 EVSQACRKQVEFYFSEYNLPYDKFLRSLCEQNDGWIPITTLASFNRMKKY-RPVDKVVDC 79
+ Q KQ+E+YF NLP DKFL+ +++DGW+PITT+ +FNR+ + +K+ +
Sbjct: 11 DADQKIIKQLEYYFGNINLPRDKFLQEKLKEDDGWVPITTMLNFNRLASISKDTEKIANA 70
Query: 80 LKD--STILEVSADGENVRRKS----PLETVDFKDRNERVLVFMNFKKIENXXXXXXXXX 133
+K+ S I+ VS D + +RR P ++++ + + V+M
Sbjct: 71 VKNSGSGIISVSEDNQKIRRNEENPVPENSLEYWQKIKHRTVYMK--------GFSTDTQ 122
Query: 134 XXXXXXXXNGFTTVNQVRLK--KDHKKYFNGVVEVEFKTKEEC-------VKFFEEHKT 183
N F V ++ K + F G V + +KT+EE VKF E T
Sbjct: 123 LDDIIQWANQFGETENVLMRRLKPGDRTFKGSVFITYKTREEAEAAQKAEVKFGETELT 181
>Hs10835067 [A] KOG4213 RNA-binding protein La
Length = 408
Score = 65.5 bits (158), Expect = 8e-11
Identities = 50/194 (25%), Positives = 87/194 (44%), Gaps = 25/194 (12%)
Query: 29 QVEFYFSEYNLPYDKFLRSLCEQNDGWIPITTLASFNRMKKY-RPVDKVVDCLKDS--TI 85
Q+E+YF ++NLP DKFL+ + ++GW+P+ + FNR+ + + +V+ L S +
Sbjct: 20 QIEYYFGDFNLPRDKFLKEQIKLDEGWVPLEIMIKFNRLNRLTTDFNVIVEALSKSKAEL 79
Query: 86 LEVSADGENVRR--KSPLETV------DFKDRNERVLVFMNFKKIENXXXXXXXXXXXXX 137
+E+S D +RR PL V D K+R+ + F +++
Sbjct: 80 MEISEDKTKIRRSPSKPLPEVTDEYKNDVKNRSVYIKGFPTDATLDDIKEWLEDKG---- 135
Query: 138 XXXXNGFTTVNQVRLKKDHKKYFNGVVEVEFKTKEECVKFFEEHKTDFSYQGQPLEVVTK 197
V +++++ K F G + V F + E KF E Y+ L ++ K
Sbjct: 136 --------QVLNIQMRRTLHKAFKGSIFVVFDSIESAKKFVE--TPGQKYKETDLLILFK 185
Query: 198 KQYSLAKNATRSKN 211
Y KN R +N
Sbjct: 186 DDYFAKKNEERKQN 199
>At2g43970 [R] KOG1855 Predicted RNA-binding protein
Length = 529
Score = 58.9 bits (141), Expect = 7e-09
Identities = 41/123 (33%), Positives = 66/123 (53%), Gaps = 6/123 (4%)
Query: 2 SFSQEIRRRGSYAPIDFT---PEVS-QACRKQVEFYFSEYNLPY-DKFLRSLCEQNDGWI 56
S + ++ G+ ID PE S Q QVE+YFS+ NL D +R +C+ +G++
Sbjct: 169 SKNDQVTETGASVSIDSKTGLPEDSIQKIVNQVEYYFSDLNLATTDHLMRFICKDPEGYV 228
Query: 57 PITTLASFNRMKK-YRPVDKVVDCLKDSTILEVSADGENVRRKSPLETVDFKDRNERVLV 115
PI +ASF ++K ++ L++S L VS DG+ VRR SP+ ++ R++V
Sbjct: 229 PIHVVASFKKIKAVINNNSQLAAVLQNSAKLFVSEDGKKVRRISPITESAIEELQSRIIV 288
Query: 116 FMN 118
N
Sbjct: 289 AEN 291
>At1g79880 [R] KOG0118 FOG: RRM domain
Length = 384
Score = 58.9 bits (141), Expect = 7e-09
Identities = 53/204 (25%), Positives = 90/204 (43%), Gaps = 36/204 (17%)
Query: 18 FTPEVSQACRKQVEFYFSEYNLPYDKFL-RSLCEQNDGWIPITTLASFNRMKKY------ 70
F E ++ QVEFYFS+ NLP D FL R + + DG + + + SF+RM+
Sbjct: 5 FNEETAKKLLTQVEFYFSDSNLPTDGFLNREVTKSKDGLVSLPLVCSFSRMRNLLGLGNI 64
Query: 71 -------RPVDKVVDCLKDSTILEVSADGENVRRKSPLETVD--FKDRNERVLVFMNFK- 120
R V++V + L+ S L+VS +G+ + R + L + + + R L F+
Sbjct: 65 NREDIPPRIVEEVANLLRTSDFLKVSNNGQRIGRGTKLSKPEEVLEQVHRRTLAASPFEY 124
Query: 121 --KIENXXXXXXXXXXXXXXXXXNGFTTVNQVRLKKD--HKKYFNGVVEVEFKTKEECVK 176
K+E+ + + VN VRL + K+ F G VEF ++++
Sbjct: 125 SIKMED------------VSSFFSQYAKVNSVRLPPNIADKRRFCGTALVEFSSEQDTQD 172
Query: 177 FFEEHKTDFSYQGQPLEVVTKKQY 200
+ Y G L ++ K +
Sbjct: 173 ILRQ---SLVYAGADLVLIPKSDF 193
>7298671 [A] KOG4213 RNA-binding protein La
Length = 390
Score = 56.6 bits (135), Expect = 4e-08
Identities = 53/237 (22%), Positives = 99/237 (41%), Gaps = 19/237 (8%)
Query: 24 QACRKQVEFYFSEYNLPYDKFLRSLCEQN-DGWIPITTLASFNRMKKY-RPVDKVVDCLK 81
+A +QVE+YF + NL DKFLR +N DGW+P++ L +F R+ + ++V L
Sbjct: 52 RAIIRQVEYYFGDANLNRDKFLREQIGKNEDGWVPLSVLVTFKRLASLSTDLSEIVAALN 111
Query: 82 DST--ILEVSADGENVRRKSPLETVDFKDRNERVLVFMNFKKIENXXXXXXXXXXXXXXX 139
S ++E+S D ++RR + + + + ++
Sbjct: 112 KSEEGLVEISEDKLSLRRHPERPIPEHNEERRKEIQ----ERTAYAKGFPLDSQISELLD 167
Query: 140 XXNGFTTVNQVRLKKDHKK-----YFNGVVEVEFKTKEECVKFFEEHKTDFS----YQGQ 190
+ V + ++K + K F G + + F+TK++ F E+ K + +
Sbjct: 168 FAANYDKVVNLTMRKHYDKPTKSYKFKGSIFLTFETKDQAKAFLEQEKIVYKERELLRKW 227
Query: 191 PLEVVTKKQYSLAKNATRSKNFGGSGQKTRSLTGYRKNIPKTNDETPEASSESKLSE 247
++ + +KQ A+ + KN K KN + PE SS ++ E
Sbjct: 228 QVDYLKEKQEEYAQKNEKRKN--KKEAKPEPAFELPKNAIVVFEGAPETSSREEIRE 282
>Hs22043788_2 [A] KOG4213 RNA-binding protein La
Length = 116
Score = 55.1 bits (131), Expect = 1e-07
Identities = 29/88 (32%), Positives = 51/88 (57%), Gaps = 5/88 (5%)
Query: 29 QVEFYFSEYNLPYDKFLRSLCEQNDGWIPITTLASFNRMKKY-RPVDKVVDCLKDS--TI 85
Q+E+YF ++NLP DKFLR + ++GW+ + + FNR+ + +V+ L S +
Sbjct: 21 QIEYYFGDFNLPGDKFLREQIKLDEGWVSLEIMIKFNRLNHLTTDFNVIVEALSKSKAEL 80
Query: 86 LEVSADGENVRRKS--PLETVDFKDRNE 111
+++S D +RR S PL V + +N+
Sbjct: 81 MKISEDKTKIRRSSSKPLPEVTDEYKND 108
>CE28950 [OJ] KOG2590 RNA-binding protein LARP/SRO9 and related La domain
proteins
Length = 1109
Score = 54.3 bits (129), Expect = 2e-07
Identities = 29/71 (40%), Positives = 45/71 (62%), Gaps = 2/71 (2%)
Query: 27 RKQVEFYFSEYNLPYDKFLRSLCEQNDGWIPITTLASFNRMKKY-RPVDKVVDCLKDSTI 85
RKQ+E+YFSE NL D FLR +G++P+ +ASF R++ +++ LKDST
Sbjct: 525 RKQIEYYFSEENLQKDFFLRRKMGP-EGYLPVALIASFPRVRSLTEDYSLILEALKDSTK 583
Query: 86 LEVSADGENVR 96
+++S DG +R
Sbjct: 584 VDMSPDGLQIR 594
>CE28663 [T] KOG2591 c-Mpl binding protein contains La domain
Length = 692
Score = 53.9 bits (128), Expect = 2e-07
Identities = 30/78 (38%), Positives = 48/78 (61%), Gaps = 4/78 (5%)
Query: 21 EVSQACRKQVEFYFSEYNLPYDKFLRSLCE-QNDGWIPITTLASFNR-MKKYRPVDKVVD 78
E+ Q + Q+E+YFS NL D++L+ C+ +D ++PI LA F + M+ VD +V+
Sbjct: 100 EIKQLLKNQLEYYFSRENLSSDRYLK--CQMDSDNYVPINVLAGFPKIMRLTTDVDLIVE 157
Query: 79 CLKDSTILEVSADGENVR 96
LK+ST +E+ E VR
Sbjct: 158 ALKESTNVELDEKFEKVR 175
>7291035 [R] KOG0118 FOG: RRM domain
Length = 595
Score = 53.5 bits (127), Expect = 3e-07
Identities = 36/113 (31%), Positives = 59/113 (51%), Gaps = 15/113 (13%)
Query: 14 APIDFTPEVSQACRK-----------QVEFYFSEYNLPYDKFLRSLCEQNDGWIPITTLA 62
AP D +P+ RK Q+EFYF + NL D+FLR EQ D ++P+
Sbjct: 40 APEDASPDKKDGGRKRKRHLFNSIRGQMEFYFGDANLSKDRFLRRYVEQ-DPYVPLEIFL 98
Query: 63 SFNRMKKY-RPVDKVVDCLKDSTILEVSADGENVRRKSPLETVDFKDRNERVL 114
+FN++K + V ++ L +S +LE+ V+R++ L D +D N++ L
Sbjct: 99 TFNKIKTLTQDVQQIAKALSNSQLLELDETELKVKRRTKLP--DQRDVNDKTL 149
>7301667 [OJ] KOG2590 RNA-binding protein LARP/SRO9 and related La domain
proteins
Length = 1184
Score = 50.4 bits (119), Expect = 3e-06
Identities = 32/79 (40%), Positives = 50/79 (62%), Gaps = 3/79 (3%)
Query: 22 VSQACRKQVEFYFSEYNLPYDKFLRSLCEQNDGWIPITTLASFNR-MKKYRPVDKVVDCL 80
+ +A +KQVE+YFS NL D FLR + +G+IP+T +ASF+R + V +V+ +
Sbjct: 473 IKEAIKKQVEYYFSVDNLTGDFFLRRKMDP-EGYIPVTLIASFHRVLALTTDVAVIVNAI 531
Query: 81 KDSTILEVSADGENVRRKS 99
K+S LE+ +G VR K+
Sbjct: 532 KESDKLEL-FEGYKVRTKT 549
>Hs22049862 [OJ] KOG2590 RNA-binding protein LARP/SRO9 and related La domain
proteins
Length = 891
Score = 49.7 bits (117), Expect = 4e-06
Identities = 30/77 (38%), Positives = 47/77 (60%), Gaps = 4/77 (5%)
Query: 27 RKQVEFYFSEYNLPYDKFLRSLCEQNDGWIPITTLASFNRMKKY-RPVDKVVDCLKDSTI 85
++Q+E+YFS NL D FLR + DG++PIT +ASF+R++ + + LKDS +
Sbjct: 203 KRQIEYYFSVDNLERDFFLRRKMDA-DGFLPITLIASFHRVQALTTDISLIFAALKDSKV 261
Query: 86 LEVSADGENVRRKSPLE 102
+E+ E VRR+ E
Sbjct: 262 VEIV--DEKVRRREEPE 276
Database: KOG eukaryal database 04/03
Posted date: Apr 14, 2003 1:07 PM
Number of letters in database: 30,389,216
Number of sequences in database: 60,738
Lambda K H
0.314 0.132 0.375
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 14,699,619
Number of Sequences: 60738
Number of extensions: 600176
Number of successful extensions: 1333
Number of sequences better than 1.0e-05: 16
Number of HSP's better than 0.0 without gapping: 5
Number of HSP's successfully gapped in prelim test: 11
Number of HSP's that attempted gapping in prelim test: 1306
Number of HSP's gapped (non-prelim): 20
length of query: 266
length of database: 30,389,216
effective HSP length: 104
effective length of query: 162
effective length of database: 24,072,464
effective search space: 3899739168
effective search space used: 3899739168
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (22.0 bits)