ORF STATUS Function Best COG Functional category Pathways and functional systems
r_klactV0537 good B KOG1342 Chromatin structure and dynamics Histone deacetylase complex, catalytic component RPD3
Only best alignment is shown:
BLASTP 2.2.3 [May-13-2002]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= r_klactV0537 187475 186180 -432
(432 letters)
Database: KOG eukaryal database 04/03
60,738 sequences; 30,389,216 total letters
Searching..................................................done
Color Key for Alignment Scores: 
Score E
Sequences producing significant alignments: (bits) Value
YNL330c [B] KOG1342 Histone deacetylase complex catalytic compon... 753 0.0
Hs20551695 [B] KOG1342 Histone deacetylase complex catalytic com... 530 e-150
7292522 [B] KOG1342 Histone deacetylase complex catalytic compon... 523 e-148
Hs13128860 [B] KOG1342 Histone deacetylase complex catalytic com... 522 e-148
Hs4557641 [B] KOG1342 Histone deacetylase complex catalytic comp... 521 e-147
SPBC36.05c [B] KOG1342 Histone deacetylase complex catalytic com... 513 e-145
CE08952 [B] KOG1342 Histone deacetylase complex catalytic compon... 495 e-140
Hs13128862 [B] KOG1342 Histone deacetylase complex catalytic com... 485 e-137
CE18116 [B] KOG1342 Histone deacetylase complex catalytic compon... 485 e-137
At4g38130 [B] KOG1342 Histone deacetylase complex catalytic comp... 479 e-135
At5g63110 [B] KOG1342 Histone deacetylase complex catalytic comp... 469 e-132
7296744 [B] KOG1342 Histone deacetylase complex catalytic compon... 461 e-129
ECU03g1370 [B] KOG1342 Histone deacetylase complex catalytic com... 454 e-128
At3g44680 [B] KOG1342 Histone deacetylase complex catalytic comp... 439 e-123
SPAC3G9.07c [B] KOG1342 Histone deacetylase complex catalytic co... 417 e-116
YGL194c [B] KOG1342 Histone deacetylase complex catalytic compon... 404 e-112
CE01472 [B] KOG1342 Histone deacetylase complex catalytic compon... 382 e-106
At5g35600 [B] KOG1342 Histone deacetylase complex catalytic comp... 351 1e-96
ECU09g0670 [B] KOG1342 Histone deacetylase complex catalytic com... 312 7e-85
Hs8923769 [B] KOG1342 Histone deacetylase complex catalytic comp... 299 6e-81
YPR068c [B] KOG1342 Histone deacetylase complex catalytic compon... 168 2e-41
YNL021w [B] KOG1343 Histone deacetylase complex catalytic compon... 127 3e-29
7293057 [B] KOG1343 Histone deacetylase complex catalytic compon... 121 2e-27
At3g18520 [B] KOG1343 Histone deacetylase complex catalytic comp... 114 3e-25
At1g08460 [B] KOG1343 Histone deacetylase complex catalytic comp... 113 6e-25
Hs5174481 [B] KOG1343 Histone deacetylase complex catalytic comp... 109 9e-24
Hs17158039 [B] KOG1343 Histone deacetylase complex catalytic com... 106 6e-23
SPBC800.03 [B] KOG1343 Histone deacetylase complex catalytic com... 105 1e-22
Hs4885531 [B] KOG1343 Histone deacetylase complex catalytic comp... 104 2e-22
Hs13128864 [B] KOG1343 Histone deacetylase complex catalytic com... 101 2e-21
Hs13259524 [B] KOG1343 Histone deacetylase complex catalytic com... 100 3e-21
Hs13259522 [B] KOG1343 Histone deacetylase complex catalytic com... 100 3e-21
CE25887 [B] KOG1343 Histone deacetylase complex catalytic compon... 99 2e-20
CE20772 [B] KOG1343 Histone deacetylase complex catalytic compon... 99 2e-20
Hs21237799 [B] KOG1343 Histone deacetylase complex catalytic com... 96 1e-19
CE08062 [B] KOG1343 Histone deacetylase complex catalytic compon... 95 2e-19
7292853 [B] KOG1343 Histone deacetylase complex catalytic compon... 94 5e-19
CE24411 [B] KOG1343 Histone deacetylase complex catalytic compon... 89 1e-17
At5g61060 [B] KOG1343 Histone deacetylase complex catalytic comp... 89 1e-17
At4g33470 [B] KOG1343 Histone deacetylase complex catalytic comp... 87 4e-17
At3g44490 [B] KOG1342 Histone deacetylase complex catalytic comp... 87 6e-17
Hs20070354 [B] KOG1343 Histone deacetylase complex catalytic com... 86 1e-16
Hs13376228 [B] KOG1344 Predicted histone deacetylase 79 1e-14
Hs17158041 [B] KOG1343 Histone deacetylase complex catalytic com... 77 7e-14
At5g61070 [B] KOG1343 Histone deacetylase complex catalytic comp... 76 9e-14
7301219 [B] KOG1344 Predicted histone deacetylase 72 2e-12
At5g26040 [B] KOG1344 Predicted histone deacetylase 60 8e-09
CE20787 [B] KOG1343 Histone deacetylase complex catalytic compon... 59 1e-08
At3g44660 [B] KOG1342 Histone deacetylase complex catalytic comp... 57 5e-08
>YNL330c [B] KOG1342 Histone deacetylase complex catalytic component RPD3
Length = 433
Score = 753 bits (1943), Expect = 0.0
Identities = 357/432 (82%), Positives = 380/432 (87%)
Query: 1 MVYEAKPFDPITVKANEKKRVAYFYDADVGNYAYGAGHPMKPHRIRMTHSLIMNYGLYKK 60
MVYEA PFDPITVK ++K+RVAYFYDADVGNYAYGAGHPMKPHRIRM HSLIMNYGLYKK
Sbjct: 1 MVYEATPFDPITVKPSDKRRVAYFYDADVGNYAYGAGHPMKPHRIRMAHSLIMNYGLYKK 60
Query: 61 MEIYRAKPATKQEMCQFHTDEYIDFLSRVTPDNLDMFQKESVKFNVGDDCPVFDGLYEYC 120
MEIYRAKPATKQEMCQFHTDEYIDFLSRVTPDNL+MF++ESVKFNVGDDCPVFDGLYEYC
Sbjct: 61 MEIYRAKPATKQEMCQFHTDEYIDFLSRVTPDNLEMFKRESVKFNVGDDCPVFDGLYEYC 120
Query: 121 SISGGGSMEGAARLNRGKCDVAINYAGGLHHAKKSEASGFCYLNDIVLGIIELLRYHPRV 180
SISGGGSMEGAARLNRGKCDVA+NYAGGLHHAKKSEASGFCYLNDIVLGIIELLRYHPRV
Sbjct: 121 SISGGGSMEGAARLNRGKCDVAVNYAGGLHHAKKSEASGFCYLNDIVLGIIELLRYHPRV 180
Query: 181 LYIDIDVHHGDGVEEAFYTTDRVMTCSFHKYGEFFPGTGELRDTGVGKGKYYAVNVPLRD 240
LYIDIDVHHGDGVEEAFYTTDRVMTCSFHKYGEFFPGTGELRD GVG GK YAVNVPLRD
Sbjct: 181 LYIDIDVHHGDGVEEAFYTTDRVMTCSFHKYGEFFPGTGELRDIGVGAGKNYAVNVPLRD 240
Query: 241 GIDDATYKSVFEPVIGKIMEWYQPSAVVLQCGGDSLSGDRLGCFNLSMKGHANCVNYMKS 300
GIDDATY+SVFEPVI KIMEWYQPSAVVLQCGGDSLSGDRLGCFNLSM+GHANCVNY+KS
Sbjct: 241 GIDDATYRSVFEPVIKKIMEWYQPSAVVLQCGGDSLSGDRLGCFNLSMEGHANCVNYVKS 300
Query: 301 FGVPLMIVGGGGYTMRNVARTWAFETGILNNVIXXXXXXXXXXXXXXXXXXXXXVRPSNM 360
FG+P+M+VGGGGYTMRNVARTW FETG+LNNV+ VRPSNM
Sbjct: 301 FGIPMMVVGGGGYTMRNVARTWCFETGLLNNVVLDKDLPYNEYYEYYGPDYKLSVRPSNM 360
Query: 361 YNVNTPEYLDKVLLNIFSNLEHTKYAPSVQLNHVPRXXXXXXXXXXXXXXXXXXRGGSQY 420
+NVNTPEYLDKV+ NIF+NLE+TKYAPSVQLNH PR +GGSQY
Sbjct: 361 FNVNTPEYLDKVMTNIFANLENTKYAPSVQLNHTPRDAEDLGDVEEDSAEAKDTKGGSQY 420
Query: 421 ARDITIENATEF 432
ARD+ +E+ EF
Sbjct: 421 ARDLHVEHDNEF 432
>Hs20551695 [B] KOG1342 Histone deacetylase complex catalytic component RPD3
Length = 488
Score = 530 bits (1365), Expect = e-150
Identities = 238/378 (62%), Positives = 296/378 (77%)
Query: 18 KKRVAYFYDADVGNYAYGAGHPMKPHRIRMTHSLIMNYGLYKKMEIYRAKPATKQEMCQF 77
KK+V Y+YD D+GNY YG GHPMKPHRIRMTH+L++NYGLY+KMEIYR AT +EM ++
Sbjct: 9 KKKVCYYYDGDIGNYYYGQGHPMKPHRIRMTHNLLLNYGLYRKMEIYRPHKATAEEMTKY 68
Query: 78 HTDEYIDFLSRVTPDNLDMFQKESVKFNVGDDCPVFDGLYEYCSISGGGSMEGAARLNRG 137
H+DEYI FL + PDN+ + K+ +FNVG+DCPVFDGL+E+C +S GGS+ GA +LNR
Sbjct: 69 HSDEYIKFLRSIRPDNMSEYSKQMQRFNVGEDCPVFDGLFEFCQLSTGGSVAGAVKLNRQ 128
Query: 138 KCDVAINYAGGLHHAKKSEASGFCYLNDIVLGIIELLRYHPRVLYIDIDVHHGDGVEEAF 197
+ D+A+N+AGGLHHAKKSEASGFCY+NDIVL I+ELL+YH RVLYIDID+HHGDGVEEAF
Sbjct: 129 QTDMAVNWAGGLHHAKKSEASGFCYVNDIVLAILELLKYHQRVLYIDIDIHHGDGVEEAF 188
Query: 198 YTTDRVMTCSFHKYGEFFPGTGELRDTGVGKGKYYAVNVPLRDGIDDATYKSVFEPVIGK 257
YTTDRVMT SFHKYGE+FPGTG+LRD G GKGKYYAVN P+RDGIDD +Y +F+P+I K
Sbjct: 189 YTTDRVMTVSFHKYGEYFPGTGDLRDIGAGKGKYYAVNFPMRDGIDDESYGQIFKPIISK 248
Query: 258 IMEWYQPSAVVLQCGGDSLSGDRLGCFNLSMKGHANCVNYMKSFGVPLMIVGGGGYTMRN 317
+ME YQPSAVVLQCG DSLSGDRLGCFNL++KGHA CV +K+F +PL+++GGGGYT+RN
Sbjct: 249 VMEMYQPSAVVLQCGADSLSGDRLGCFNLTVKGHAKCVEVVKTFNLPLLMLGGGGYTIRN 308
Query: 318 VARTWAFETGILNNVIXXXXXXXXXXXXXXXXXXXXXVRPSNMYNVNTPEYLDKVLLNIF 377
VAR W +ET + + + PSNM N NTPEY++K+ +F
Sbjct: 309 VARCWTYETAVALDCEIPNELPYNDYFEYFGPDFKLHISPSNMTNQNTPEYMEKIKQRLF 368
Query: 378 SNLEHTKYAPSVQLNHVP 395
NL +AP VQ+ +P
Sbjct: 369 ENLRMLPHAPGVQMQAIP 386
>7292522 [B] KOG1342 Histone deacetylase complex catalytic component RPD3
Length = 521
Score = 523 bits (1348), Expect = e-148
Identities = 234/383 (61%), Positives = 295/383 (76%)
Query: 13 VKANEKKRVAYFYDADVGNYAYGAGHPMKPHRIRMTHSLIMNYGLYKKMEIYRAKPATKQ 72
++++ KKRV Y+YD+D+GNY YG GHPMKPHRIRMTH+L++NYGLY+KMEIYR AT
Sbjct: 1 MQSHSKKRVCYYYDSDIGNYYYGQGHPMKPHRIRMTHNLLLNYGLYRKMEIYRPHKATAD 60
Query: 73 EMCQFHTDEYIDFLSRVTPDNLDMFQKESVKFNVGDDCPVFDGLYEYCSISGGGSMEGAA 132
EM +FH+DEY+ FL + PDN+ + K+ +FNVG+DCPVFDGLYE+C +S GGS+ A
Sbjct: 61 EMTKFHSDEYVRFLRSIRPDNMSEYNKQMQRFNVGEDCPVFDGLYEFCQLSAGGSVAAAV 120
Query: 133 RLNRGKCDVAINYAGGLHHAKKSEASGFCYLNDIVLGIIELLRYHPRVLYIDIDVHHGDG 192
+LN+ ++ IN+ GGLHHAKKSEASGFCY+NDIVLGI+ELL+YH RVLYIDIDVHHGDG
Sbjct: 121 KLNKQASEICINWGGGLHHAKKSEASGFCYVNDIVLGILELLKYHQRVLYIDIDVHHGDG 180
Query: 193 VEEAFYTTDRVMTCSFHKYGEFFPGTGELRDTGVGKGKYYAVNVPLRDGIDDATYKSVFE 252
VEEAFYTTDRVMT SFHKYGE+FPGTG+LRD G GKGKYYAVN+PLRDG+DD Y+S+F
Sbjct: 181 VEEAFYTTDRVMTVSFHKYGEYFPGTGDLRDIGAGKGKYYAVNIPLRDGMDDDAYESIFV 240
Query: 253 PVIGKIMEWYQPSAVVLQCGGDSLSGDRLGCFNLSMKGHANCVNYMKSFGVPLMIVGGGG 312
P+I K+ME +QP+AVVLQCG DSL+GDRLGCFNL++KGH CV ++K + +P ++VGGGG
Sbjct: 241 PIISKVMETFQPAAVVLQCGADSLTGDRLGCFNLTVKGHGKCVEFVKKYNLPFLMVGGGG 300
Query: 313 YTMRNVARTWAFETGILNNVIXXXXXXXXXXXXXXXXXXXXXVRPSNMYNVNTPEYLDKV 372
YT+RNV+R W +ET + V + PSNM N NT EYL+K+
Sbjct: 301 YTIRNVSRCWTYETSVALAVEIANELPYNDYFEYFGPDFKLHISPSNMTNQNTSEYLEKI 360
Query: 373 LLNIFSNLEHTKYAPSVQLNHVP 395
+F NL +AP VQ+ +P
Sbjct: 361 KNRLFENLRMLPHAPGVQIQAIP 383
>Hs13128860 [B] KOG1342 Histone deacetylase complex catalytic component RPD3
Length = 482
Score = 522 bits (1344), Expect = e-148
Identities = 233/378 (61%), Positives = 296/378 (77%)
Query: 18 KKRVAYFYDADVGNYAYGAGHPMKPHRIRMTHSLIMNYGLYKKMEIYRAKPATKQEMCQF 77
+++V Y+YD DVGNY YG GHPMKPHRIRMTH+L++NYGLY+KMEIYR A +EM ++
Sbjct: 8 RRKVCYYYDGDVGNYYYGQGHPMKPHRIRMTHNLLLNYGLYRKMEIYRPHKANAEEMTKY 67
Query: 78 HTDEYIDFLSRVTPDNLDMFQKESVKFNVGDDCPVFDGLYEYCSISGGGSMEGAARLNRG 137
H+D+YI FL + PDN+ + K+ +FNVG+DCPVFDGL+E+C +S GGS+ A +LN+
Sbjct: 68 HSDDYIKFLRSIRPDNMSEYSKQMQRFNVGEDCPVFDGLFEFCQLSTGGSVASAVKLNKQ 127
Query: 138 KCDVAINYAGGLHHAKKSEASGFCYLNDIVLGIIELLRYHPRVLYIDIDVHHGDGVEEAF 197
+ D+A+N+AGGLHHAKKSEASGFCY+NDIVL I+ELL+YH RVLYIDID+HHGDGVEEAF
Sbjct: 128 QTDIAVNWAGGLHHAKKSEASGFCYVNDIVLAILELLKYHQRVLYIDIDIHHGDGVEEAF 187
Query: 198 YTTDRVMTCSFHKYGEFFPGTGELRDTGVGKGKYYAVNVPLRDGIDDATYKSVFEPVIGK 257
YTTDRVMT SFHKYGE+FPGTG+LRD G GKGKYYAVN PLRDGIDD +Y+++F+PV+ K
Sbjct: 188 YTTDRVMTVSFHKYGEYFPGTGDLRDIGAGKGKYYAVNYPLRDGIDDESYEAIFKPVMSK 247
Query: 258 IMEWYQPSAVVLQCGGDSLSGDRLGCFNLSMKGHANCVNYMKSFGVPLMIVGGGGYTMRN 317
+ME +QPSAVVLQCG DSLSGDRLGCFNL++KGHA CV ++KSF +P++++GGGGYT+RN
Sbjct: 248 VMEMFQPSAVVLQCGSDSLSGDRLGCFNLTIKGHAKCVEFVKSFNLPMLMLGGGGYTIRN 307
Query: 318 VARTWAFETGILNNVIXXXXXXXXXXXXXXXXXXXXXVRPSNMYNVNTPEYLDKVLLNIF 377
VAR W +ET + + + PSNM N NT EYL+K+ +F
Sbjct: 308 VARCWTYETAVALDTEIPNELPYNDYFEYFGPDFKLHISPSNMTNQNTNEYLEKIKQRLF 367
Query: 378 SNLEHTKYAPSVQLNHVP 395
NL +AP VQ+ +P
Sbjct: 368 ENLRMLPHAPGVQMQAIP 385
>Hs4557641 [B] KOG1342 Histone deacetylase complex catalytic component RPD3
Length = 488
Score = 521 bits (1341), Expect = e-147
Identities = 235/378 (62%), Positives = 292/378 (77%)
Query: 18 KKRVAYFYDADVGNYAYGAGHPMKPHRIRMTHSLIMNYGLYKKMEIYRAKPATKQEMCQF 77
KK+V Y+YD D+GNY YG GHPMKPHRIRMTH+L++NYGLY+KMEIYR AT +EM ++
Sbjct: 9 KKKVCYYYDGDIGNYYYGQGHPMKPHRIRMTHNLLLNYGLYRKMEIYRPHKATAEEMTKY 68
Query: 78 HTDEYIDFLSRVTPDNLDMFQKESVKFNVGDDCPVFDGLYEYCSISGGGSMEGAARLNRG 137
H+DEYI FL + PDN+ + K+ FNVG+DCP FDGL+E+C +S GGS+ GA +LNR
Sbjct: 69 HSDEYIKFLRSIRPDNMSEYSKQMHIFNVGEDCPAFDGLFEFCQLSTGGSVAGAVKLNRQ 128
Query: 138 KCDVAINYAGGLHHAKKSEASGFCYLNDIVLGIIELLRYHPRVLYIDIDVHHGDGVEEAF 197
+ D+A+N+AGGLHHAKK EASGFCY+NDIVL I+ELL+YH RVLYIDID+HHGDGVEEAF
Sbjct: 129 QTDMAVNWAGGLHHAKKYEASGFCYVNDIVLAILELLKYHQRVLYIDIDIHHGDGVEEAF 188
Query: 198 YTTDRVMTCSFHKYGEFFPGTGELRDTGVGKGKYYAVNVPLRDGIDDATYKSVFEPVIGK 257
YTTDRVMT SFHKYGE+FPGTG+LRD G GKGKYYAVN P+ DGIDD +Y +F+P+I K
Sbjct: 189 YTTDRVMTVSFHKYGEYFPGTGDLRDIGAGKGKYYAVNFPMCDGIDDESYGQIFKPIISK 248
Query: 258 IMEWYQPSAVVLQCGGDSLSGDRLGCFNLSMKGHANCVNYMKSFGVPLMIVGGGGYTMRN 317
+ME YQPSAVVLQCG DSLSGDRLGCFNL++KGHA CV +K+F +PL+++GGGGYT+RN
Sbjct: 249 VMEMYQPSAVVLQCGADSLSGDRLGCFNLTVKGHAKCVEVVKTFNLPLLMLGGGGYTIRN 308
Query: 318 VARTWAFETGILNNVIXXXXXXXXXXXXXXXXXXXXXVRPSNMYNVNTPEYLDKVLLNIF 377
VAR W +ET + + + PSNM N NTPEY++K+ +F
Sbjct: 309 VARCWTYETAVALDCEIPNELPYNDYFEYFGPDFKLHISPSNMTNQNTPEYMEKIKQRLF 368
Query: 378 SNLEHTKYAPSVQLNHVP 395
NL +AP VQ+ +P
Sbjct: 369 ENLRMLPHAPGVQMQAIP 386
>SPBC36.05c [B] KOG1342 Histone deacetylase complex catalytic component RPD3
Length = 405
Score = 513 bits (1322), Expect = e-145
Identities = 235/378 (62%), Positives = 289/378 (76%)
Query: 18 KKRVAYFYDADVGNYAYGAGHPMKPHRIRMTHSLIMNYGLYKKMEIYRAKPATKQEMCQF 77
KK+V+YFYD DVGNY YG HPMKPHR+RM H+L++NY LY+K+ + AT+ +M +
Sbjct: 5 KKKVSYFYDEDVGNYHYGPQHPMKPHRVRMVHNLVVNYNLYEKLNVITPVRATRNDMTRC 64
Query: 78 HTDEYIDFLSRVTPDNLDMFQKESVKFNVGDDCPVFDGLYEYCSISGGGSMEGAARLNRG 137
HTDEYI+FL RVTPD ++ FQ +KFNVGDDCPVFDGLYE+CSIS GGS+ A LN G
Sbjct: 65 HTDEYIEFLWRVTPDTMEKFQPHQLKFNVGDDCPVFDGLYEFCSISAGGSIGAAQELNSG 124
Query: 138 KCDVAINYAGGLHHAKKSEASGFCYLNDIVLGIIELLRYHPRVLYIDIDVHHGDGVEEAF 197
++AIN+AGGLHHAKK EASGFCY+NDI L +ELL+YH RVLYIDIDVHHGDGVEE F
Sbjct: 125 NAEIAINWAGGLHHAKKREASGFCYVNDIALAALELLKYHQRVLYIDIDVHHGDGVEEFF 184
Query: 198 YTTDRVMTCSFHKYGEFFPGTGELRDTGVGKGKYYAVNVPLRDGIDDATYKSVFEPVIGK 257
YTTDRVMTCSFHK+GE+FPGTG ++DTG+G GK YAVNVPLRDGIDD +Y+SVF+PVI
Sbjct: 185 YTTDRVMTCSFHKFGEYFPGTGHIKDTGIGTGKNYAVNVPLRDGIDDESYESVFKPVISH 244
Query: 258 IMEWYQPSAVVLQCGGDSLSGDRLGCFNLSMKGHANCVNYMKSFGVPLMIVGGGGYTMRN 317
IM+W++P AV+LQCG DSL+GDRLGCFNLSMKGH+ CV+++KSF +P++ VGGGGYT+RN
Sbjct: 245 IMQWFRPEAVILQCGTDSLAGDRLGCFNLSMKGHSMCVDFVKSFNLPMICVGGGGYTVRN 304
Query: 318 VARTWAFETGILNNVIXXXXXXXXXXXXXXXXXXXXXVRPSNMYNVNTPEYLDKVLLNIF 377
VAR W +ETG+L V +NM N NT +YLD + I
Sbjct: 305 VARVWTYETGLLAGEELDENLPYNDYLQYYGPDYKLNVLSNNMENHNTRQYLDSITSEII 364
Query: 378 SNLEHTKYAPSVQLNHVP 395
NL + +APSVQ++ P
Sbjct: 365 ENLRNLSFAPSVQMHKTP 382
>CE08952 [B] KOG1342 Histone deacetylase complex catalytic component RPD3
Length = 461
Score = 495 bits (1274), Expect = e-140
Identities = 225/378 (59%), Positives = 286/378 (75%)
Query: 18 KKRVAYFYDADVGNYAYGAGHPMKPHRIRMTHSLIMNYGLYKKMEIYRAKPATKQEMCQF 77
K+RVAY+YD+++GNY YG GH MKPHRIRMTH L++NYGLY+ +EI+R PA+ ++M +F
Sbjct: 12 KRRVAYYYDSNIGNYYYGQGHVMKPHRIRMTHHLVLNYGLYRNLEIFRPFPASFEDMTRF 71
Query: 78 HTDEYIDFLSRVTPDNLDMFQKESVKFNVGDDCPVFDGLYEYCSISGGGSMEGAARLNRG 137
H+DEY+ FL PDNL F K+ +KFNVG+DCP+FDGLYE+C +S GGS+ A +LN+
Sbjct: 72 HSDEYMTFLKSANPDNLKSFNKQMLKFNVGEDCPLFDGLYEFCQLSSGGSLAAATKLNKQ 131
Query: 138 KCDVAINYAGGLHHAKKSEASGFCYLNDIVLGIIELLRYHPRVLYIDIDVHHGDGVEEAF 197
K D+AIN+ GGLHHAKKSEASGFCY NDIVLGI+ELL+YH RVLY+DIDVHHGDGVEEAF
Sbjct: 132 KVDIAINWMGGLHHAKKSEASGFCYTNDIVLGILELLKYHKRVLYVDIDVHHGDGVEEAF 191
Query: 198 YTTDRVMTCSFHKYGEFFPGTGELRDTGVGKGKYYAVNVPLRDGIDDATYKSVFEPVIGK 257
YTTDRVMT SFHKYG+FFPGTG+L+D G GKGK Y+VNVPLRDGI D +Y+S+F+P++ K
Sbjct: 192 YTTDRVMTVSFHKYGDFFPGTGDLKDIGAGKGKLYSVNVPLRDGITDVSYQSIFKPIMTK 251
Query: 258 IMEWYQPSAVVLQCGGDSLSGDRLGCFNLSMKGHANCVNYMKSFGVPLMIVGGGGYTMRN 317
+ME + P AVVLQCG DSL+GDRLG FNL++KGH C + +S+ VPLM+VGGGGYT RN
Sbjct: 252 VMERFDPCAVVLQCGADSLNGDRLGPFNLTLKGHGECARFFRSYNVPLMMVGGGGYTPRN 311
Query: 318 VARTWAFETGILNNVIXXXXXXXXXXXXXXXXXXXXXVRPSNMYNVNTPEYLDKVLLNIF 377
VAR W +ET I + + SN N N+ + L K+ ++
Sbjct: 312 VARCWTYETSIAVDKEVPNELPYNDYFEYFGPNYRLHIESSNAANENSSDMLAKLQTDVI 371
Query: 378 SNLEHTKYAPSVQLNHVP 395
+NLE + PSVQ+ +P
Sbjct: 372 ANLEQLTFVPSVQMRPIP 389
>Hs13128862 [B] KOG1342 Histone deacetylase complex catalytic component RPD3
Length = 428
Score = 485 bits (1249), Expect = e-137
Identities = 221/379 (58%), Positives = 287/379 (75%), Gaps = 2/379 (0%)
Query: 19 KRVAYFYDADVGNYAYGAGHPMKPHRIRMTHSLIMNYGLYKKMEIYRAKPATKQEMCQFH 78
K VAYFYD DVGN+ YGAGHPMKPHR+ +THSL+++YGLYKKM +++ A++ +MC+FH
Sbjct: 3 KTVAYFYDPDVGNFHYGAGHPMKPHRLALTHSLVLHYGLYKKMIVFKPYQASQHDMCRFH 62
Query: 79 TDEYIDFLSRVTPDNLDMFQKESVKFNVGDDCPVFDGLYEYCSISGGGSMEGAARLNRGK 138
+++YIDFL RV+P N+ F K FNVGDDCPVF GL+E+CS G S++GA +LN
Sbjct: 63 SEDYIDFLQRVSPTNMQGFTKSLNAFNVGDDCPVFPGLFEFCSRYTGASLQGATQLNNKI 122
Query: 139 CDVAINYAGGLHHAKKSEASGFCYLNDIVLGIIELLRYHPRVLYIDIDVHHGDGVEEAFY 198
CD+AIN+AGGLHHAKK EASGFCY+NDIV+GI+ELL+YHPRVLYIDID+HHGDGV+EAFY
Sbjct: 123 CDIAINWAGGLHHAKKFEASGFCYVNDIVIGILELLKYHPRVLYIDIDIHHGDGVQEAFY 182
Query: 199 TTDRVMTCSFHKYGE-FFPGTGELRDTGVGKGKYYAVNVPLRDGIDDATYKSVFEPVIGK 257
TDRVMT SFHKYG FFPGTG++ + G G+YY +NVPLRDGIDD +YK +F+PVI +
Sbjct: 183 LTDRVMTVSFHKYGNYFFPGTGDMYEVGAESGRYYCLNVPLRDGIDDQSYKHLFQPVINQ 242
Query: 258 IMEWYQPSAVVLQCGGDSLSGDRLGCFNLSMKGHANCVNYMKSFGVPLMIVGGGGYTMRN 317
++++YQP+ +VLQCG DSL DRLGCFNLS++GH CV Y+KSF +PL+++GGGGYT+RN
Sbjct: 243 VVDFYQPTCIVLQCGADSLGCDRLGCFNLSIRGHGECVEYVKSFNIPLLVLGGGGYTVRN 302
Query: 318 VARTWAFETGIL-NNVIXXXXXXXXXXXXXXXXXXXXXVRPSNMYNVNTPEYLDKVLLNI 376
VAR W +ET +L I + + N N+ +YLD++ I
Sbjct: 303 VARCWTYETSLLVEEAISEELPYSEYFEYFAPDFTLHPDVSTRIENQNSRQYLDQIRQTI 362
Query: 377 FSNLEHTKYAPSVQLNHVP 395
F NL+ +APSVQ++ VP
Sbjct: 363 FENLKMLNHAPSVQIHDVP 381
>CE18116 [B] KOG1342 Histone deacetylase complex catalytic component RPD3
Length = 465
Score = 485 bits (1248), Expect = e-137
Identities = 224/421 (53%), Positives = 296/421 (70%), Gaps = 4/421 (0%)
Query: 16 NEKKRVAYFYDADVGNYAYGAGHPMKPHRIRMTHSLIMNYGLYKKMEIYRAKPATKQEMC 75
+ K RV+Y+YD D GN+ YG GHPMKPHR+RMTHSLI+NYGLY+K+ + R A+ E+
Sbjct: 5 HSKSRVSYYYDGDFGNFYYGQGHPMKPHRVRMTHSLIVNYGLYRKLNVMRPARASFSEIT 64
Query: 76 QFHTDEYIDFLSRVTPDNLDMFQKESVKFNVGDDCPVFDGLYEYCSISGGGSMEGAARLN 135
++H+D+YI+FL V DN+ F + +F+VG+DCPVFDG+YE+C +S GGS+ AARLN
Sbjct: 65 RYHSDDYINFLRNVKSDNMSTFTDQMARFSVGEDCPVFDGMYEFCQLSCGGSLAAAARLN 124
Query: 136 RGKCDVAINYAGGLHHAKKSEASGFCYLNDIVLGIIELLRYHPRVLYIDIDVHHGDGVEE 195
R + ++AIN+ GGLHHAKKSEASGFCY NDIVL I+ELL++H RVLYIDIDVHHGDGVEE
Sbjct: 125 RQESEIAINWMGGLHHAKKSEASGFCYSNDIVLAILELLKHHKRVLYIDIDVHHGDGVEE 184
Query: 196 AFYTTDRVMTCSFHKYGEFFPGTGELRDTGVGKGKYYAVNVPLRDGIDDATYKSVFEPVI 255
AFYTTDRVMT SFHK+GE+FPGTG+L+D G G GKYYA+NVPLRDG+DD TY+ +F ++
Sbjct: 185 AFYTTDRVMTVSFHKHGEYFPGTGDLKDVGAGSGKYYALNVPLRDGVDDVTYERIFRTIM 244
Query: 256 GKIMEWYQPSAVVLQCGGDSLSGDRLGCFNLSMKGHANCVNYMKSFGVPLMIVGGGGYTM 315
G++M +QP AVVLQCG DSL+GDRLG FNL+ GH CV YMKSF VPL++VGGGGYT+
Sbjct: 245 GEVMARFQPEAVVLQCGADSLAGDRLGVFNLTTYGHGKCVEYMKSFNVPLLLVGGGGYTI 304
Query: 316 RNVARTWAFETGILNNVIXXXXXXXXXXXXXXXXXXXXXVRP-SNMYNVNTPEYLDKVLL 374
RNV+R W +ET I N ++P + + N NTPE++D+ ++
Sbjct: 305 RNVSRCWLYETAIALNQEVSDDLPLHDYFDYFIPDYKLHIKPLAALSNFNTPEFIDQTIV 364
Query: 375 NIFSNLEHTKYAPSVQLNHVPRXXXXXXXXXXXXXXXXXXRGG---SQYARDITIENATE 431
+ NL+ + PSVQ+ + +Q+ D+ +E++ E
Sbjct: 365 ALLENLKQLPHVPSVQMQSISTSCDSIVKTFDEKLIRDHQNDDVRVTQFEEDVQVEDSAE 424
Query: 432 F 432
F
Sbjct: 425 F 425
>At4g38130 [B] KOG1342 Histone deacetylase complex catalytic component RPD3
Length = 501
Score = 479 bits (1234), Expect = e-135
Identities = 215/378 (56%), Positives = 281/378 (73%)
Query: 18 KKRVAYFYDADVGNYAYGAGHPMKPHRIRMTHSLIMNYGLYKKMEIYRAKPATKQEMCQF 77
K++V YFYD +VGNY YG GHPMKPHRIRMTH+L+ +YGL + M++ + PA +++C+F
Sbjct: 16 KRKVCYFYDPEVGNYYYGQGHPMKPHRIRMTHALLAHYGLLQHMQVLKPFPARDRDLCRF 75
Query: 78 HTDEYIDFLSRVTPDNLDMFQKESVKFNVGDDCPVFDGLYEYCSISGGGSMEGAARLNRG 137
H D+Y+ FL +TP+ ++ +FNVG+DCPVFDGLY +C GGS+ G+ +LN G
Sbjct: 76 HADDYVSFLRSITPETQQDQIRQLKRFNVGEDCPVFDGLYSFCQTYAGGSVGGSVKLNHG 135
Query: 138 KCDVAINYAGGLHHAKKSEASGFCYLNDIVLGIIELLRYHPRVLYIDIDVHHGDGVEEAF 197
CD+AIN+AGGLHHAKK EASGFCY+NDIVL I+ELL+ H RVLY+DID+HHGDGVEEAF
Sbjct: 136 LCDIAINWAGGLHHAKKCEASGFCYVNDIVLAILELLKQHERVLYVDIDIHHGDGVEEAF 195
Query: 198 YTTDRVMTCSFHKYGEFFPGTGELRDTGVGKGKYYAVNVPLRDGIDDATYKSVFEPVIGK 257
Y TDRVMT SFHK+G++FPGTG ++D G G GKYY++NVPL DGIDD +Y +F+P++GK
Sbjct: 196 YATDRVMTVSFHKFGDYFPGTGHIQDIGYGSGKYYSLNVPLDDGIDDESYHLLFKPIMGK 255
Query: 258 IMEWYQPSAVVLQCGGDSLSGDRLGCFNLSMKGHANCVNYMKSFGVPLMIVGGGGYTMRN 317
+ME ++P AVVLQCG DSLSGDRLGCFNLS+KGHA CV +M+SF VPL+++GGGGYT+RN
Sbjct: 256 VMEIFRPGAVVLQCGADSLSGDRLGCFNLSIKGHAECVKFMRSFNVPLLLLGGGGYTIRN 315
Query: 318 VARTWAFETGILNNVIXXXXXXXXXXXXXXXXXXXXXVRPSNMYNVNTPEYLDKVLLNIF 377
VAR W +ETG+ V V PSNM N N+ + L+++ ++
Sbjct: 316 VARCWCYETGVALGVEVEDKMPEHEYYEYFGPDYTLHVAPSNMENKNSRQMLEEIRNDLL 375
Query: 378 SNLEHTKYAPSVQLNHVP 395
NL ++APSV P
Sbjct: 376 HNLSKLQHAPSVPFQERP 393
>At5g63110 [B] KOG1342 Histone deacetylase complex catalytic component RPD3
Length = 471
Score = 469 bits (1208), Expect = e-132
Identities = 218/380 (57%), Positives = 283/380 (74%), Gaps = 2/380 (0%)
Query: 18 KKRVAYFYDADVGNYAYGAGHPMKPHRIRMTHSLIMNYGLYKKMEIYRAKPATKQEMCQF 77
K+RV+YFY+ +G+Y YG GHPMKPHRIRM HSLI++Y L++++EI R A ++ +F
Sbjct: 18 KRRVSYFYEPTIGDYYYGQGHPMKPHRIRMAHSLIIHYHLHRRLEISRPSLADASDIGRF 77
Query: 78 HTDEYIDFLSRVTPDNLD--MFQKESVKFNVGDDCPVFDGLYEYCSISGGGSMEGAARLN 135
H+ EY+DFL+ V+P+++ + +FNVG+DCPVFDGL+++C S GGS+ A +LN
Sbjct: 78 HSPEYVDFLASVSPESMGDPSAARNLRRFNVGEDCPVFDGLFDFCRASAGGSIGAAVKLN 137
Query: 136 RGKCDVAINYAGGLHHAKKSEASGFCYLNDIVLGIIELLRYHPRVLYIDIDVHHGDGVEE 195
R D+AIN+ GGLHHAKKSEASGFCY+NDIVLGI+ELL+ RVLYIDIDVHHGDGVEE
Sbjct: 138 RQDADIAINWGGGLHHAKKSEASGFCYVNDIVLGILELLKMFKRVLYIDIDVHHGDGVEE 197
Query: 196 AFYTTDRVMTCSFHKYGEFFPGTGELRDTGVGKGKYYAVNVPLRDGIDDATYKSVFEPVI 255
AFYTTDRVMT SFHK+G+FFPGTG +RD G KGKYYA+NVPL DG+DD +++S+F P+I
Sbjct: 198 AFYTTDRVMTVSFHKFGDFFPGTGHIRDVGAEKGKYYALNVPLNDGMDDESFRSLFRPLI 257
Query: 256 GKIMEWYQPSAVVLQCGGDSLSGDRLGCFNLSMKGHANCVNYMKSFGVPLMIVGGGGYTM 315
K+ME YQP AVVLQCG DSLSGDRLGCFNLS+KGHA+C+ +++S+ VPLM++GGGGYT+
Sbjct: 258 QKVMEVYQPEAVVLQCGADSLSGDRLGCFNLSVKGHADCLRFLRSYNVPLMVLGGGGYTI 317
Query: 316 RNVARTWAFETGILNNVIXXXXXXXXXXXXXXXXXXXXXVRPSNMYNVNTPEYLDKVLLN 375
RNVAR W +ET + V V PS M N+NTP+ ++++
Sbjct: 318 RNVARCWCYETAVAVGVEPDNKLPYNEYFEYFGPDYTLHVDPSPMENLNTPKDMERIRNT 377
Query: 376 IFSNLEHTKYAPSVQLNHVP 395
+ L +APSVQ H P
Sbjct: 378 LLEQLSGLIHAPSVQFQHTP 397
>7296744 [B] KOG1342 Histone deacetylase complex catalytic component RPD3
Length = 438
Score = 461 bits (1185), Expect = e-129
Identities = 213/383 (55%), Positives = 284/383 (73%), Gaps = 6/383 (1%)
Query: 19 KRVAYFYDADVGNYAYGAGHPMKPHRIRMTHSLIMNYGLYKKMEIYRAKPATKQEMCQFH 78
+RV+YFY+ADVGN+ YGAGHPMKP R+ +THSL+MNYGL+KKM+IYR A+ Q+M +FH
Sbjct: 4 RRVSYFYNADVGNFHYGAGHPMKPQRLAVTHSLVMNYGLHKKMKIYRPYKASAQDMLRFH 63
Query: 79 TDEYIDFLSRVTPDNLDM----FQKESVKFNVGDDCPVFDGLYEYCSISGGGSMEGAARL 134
+DEYI +L +VTP N+ + K F+VG+DCPVFDGL+++C++ G S+EGA +L
Sbjct: 64 SDEYIAYLQQVTPQNIQCNSVAYTKYLAHFSVGEDCPVFDGLFDFCAMYTGASLEGAQKL 123
Query: 135 NRGKCDVAINYAGGLHHAKKSEASGFCYLNDIVLGIIELLRYHPRVLYIDIDVHHGDGVE 194
N D+ IN++GGLHHAKK EASGFCY+NDIV+GI+ELL+YHPRVLYIDIDVHHGDGV+
Sbjct: 124 NHNHSDICINWSGGLHHAKKFEASGFCYVNDIVIGILELLKYHPRVLYIDIDVHHGDGVQ 183
Query: 195 EAFYTTDRVMTCSFHKYGE-FFPGTGELRDTGVGKGKYYAVNVPLRDGIDDATYKSVFEP 253
EAFY TDRVMT SFHKYG FFPGTG++ + G G+YY+VNVPL++GIDD +Y VF+P
Sbjct: 184 EAFYLTDRVMTASFHKYGNYFFPGTGDMYEIGAESGRYYSVNVPLKEGIDDQSYFQVFKP 243
Query: 254 VIGKIMEWYQPSAVVLQCGGDSLSGDRLGCFNLSMKGHANCVNYMKSFGVPLMIVGGGGY 313
+I IM++Y+P+A+VLQCG DSL+GDRLGCF+LS KGH CV ++K VP ++VGGGGY
Sbjct: 244 IISAIMDFYRPTAIVLQCGADSLAGDRLGCFSLSTKGHGECVKFVKELNVPTLVVGGGGY 303
Query: 314 TMRNVARTWAFETGIL-NNVIXXXXXXXXXXXXXXXXXXXXXVRPSNMYNVNTPEYLDKV 372
T+RNVAR W ET +L + I S N N+ +YL+ +
Sbjct: 304 TLRNVARCWTHETSLLVDQDIENDLPATEYYDFFAPDFTLHPEINSRQDNANSKQYLELI 363
Query: 373 LLNIFSNLEHTKYAPSVQLNHVP 395
+ +++ NL+ +++PSVQ+ P
Sbjct: 364 VKHVYENLKMCQHSPSVQMVQTP 386
>ECU03g1370 [B] KOG1342 Histone deacetylase complex catalytic component RPD3
Length = 416
Score = 454 bits (1169), Expect = e-128
Identities = 205/377 (54%), Positives = 281/377 (74%)
Query: 19 KRVAYFYDADVGNYAYGAGHPMKPHRIRMTHSLIMNYGLYKKMEIYRAKPATKQEMCQFH 78
KRV YFYD ++G ++Y GHPMKP R++MTH+L++ Y LYK M++ R A+ + + FH
Sbjct: 4 KRVVYFYDPEIGCFSYAMGHPMKPLRVKMTHTLLVGYELYKYMDVLRPFQASYENLTNFH 63
Query: 79 TDEYIDFLSRVTPDNLDMFQKESVKFNVGDDCPVFDGLYEYCSISGGGSMEGAARLNRGK 138
+YI+FLS V+ +N++ K+ KFN+ DDCPVF GLY+YC ++ GGS+ A ++N GK
Sbjct: 64 AVDYINFLSSVSSENMEEMIKDLHKFNIRDDCPVFPGLYDYCRLTSGGSIYAAQKINSGK 123
Query: 139 CDVAINYAGGLHHAKKSEASGFCYLNDIVLGIIELLRYHPRVLYIDIDVHHGDGVEEAFY 198
DVAIN+AGGLHHAK+ EASGFCY+NDIVLGI+ELL+Y+ R+LYIDID+HHGDGVEEAFY
Sbjct: 124 YDVAINWAGGLHHAKRGEASGFCYVNDIVLGILELLKYNKRILYIDIDIHHGDGVEEAFY 183
Query: 199 TTDRVMTCSFHKYGEFFPGTGELRDTGVGKGKYYAVNVPLRDGIDDATYKSVFEPVIGKI 258
TTDRVMT SFHKYG++FPGTG + DTG+ KGK Y+VNVPL+DGIDD +Y S+F+P++ K+
Sbjct: 184 TTDRVMTVSFHKYGDYFPGTGMVTDTGLAKGKGYSVNVPLKDGIDDESYFSIFKPIVSKV 243
Query: 259 MEWYQPSAVVLQCGGDSLSGDRLGCFNLSMKGHANCVNYMKSFGVPLMIVGGGGYTMRNV 318
+E YQP+A+VLQ G DSLSGD+LGCFNLS GH+ C+ +++SF +PL+++GGGGYT+ NV
Sbjct: 244 IETYQPNAIVLQSGADSLSGDKLGCFNLSHLGHSRCIKFVQSFNIPLILLGGGGYTIGNV 303
Query: 319 ARTWAFETGILNNVIXXXXXXXXXXXXXXXXXXXXXVRPSNMYNVNTPEYLDKVLLNIFS 378
++ WA+ T ++ +V V SNM N NT E L+ ++ ++
Sbjct: 304 SKAWAYGTSVVLDVDIPREIPYNEYFDYYAPTYRIDVPTSNMANQNTREGLEDIIAKVYE 363
Query: 379 NLEHTKYAPSVQLNHVP 395
NL +APSVQ+ +P
Sbjct: 364 NLRSLSHAPSVQMVSIP 380
>At3g44680 [B] KOG1342 Histone deacetylase complex catalytic component RPD3
Length = 419
Score = 439 bits (1128), Expect = e-123
Identities = 200/376 (53%), Positives = 270/376 (71%), Gaps = 5/376 (1%)
Query: 21 VAYFYDADVGNYAYGAGHPMKPHRIRMTHSLIMNYGLYKKMEIYRAKPATKQEMCQFHTD 80
V ++ DVG+ +G HPMKPHR+ MTH LI+ YGL+ KME+YR A EM QFH+
Sbjct: 4 VFFWVAGDVGSVYFGPNHPMKPHRLCMTHHLILAYGLHSKMEVYRPHKAYPIEMAQFHSP 63
Query: 81 EYIDFLSRVTPDNLDMFQKESVKFNVGDDCPVFDGLYEYCSISGGGSMEGAARLNRGKCD 140
+Y++FL R+ P+N ++F E ++N+G+DCPVF+ L+E+C + GG+++ A RLN CD
Sbjct: 64 DYVEFLQRINPENQNLFPNEMARYNLGEDCPVFEDLFEFCQLYAGGTIDAARRLNNKLCD 123
Query: 141 VAINYAGGLHHAKKSEASGFCYLNDIVLGIIELLRYHPRVLYIDIDVHHGDGVEEAFYTT 200
+AIN+AGGLHHAKK +ASGFCY+ND+VLGI+ELL++HPRVLYIDIDVHHGDGVEEAFY T
Sbjct: 124 IAINWAGGLHHAKKCDASGFCYINDLVLGILELLKHHPRVLYIDIDVHHGDGVEEAFYFT 183
Query: 201 DRVMTCSFHKYGE-FFPGTGELRDTGVGKGKYYAVNVPLRDGIDDATYKSVFEPVIGKIM 259
DRVMT SFHK+G+ FFPGTG++++ G +GK+YA+NVPL+DGIDD+++ +F V+
Sbjct: 184 DRVMTVSFHKFGDKFFPGTGDVKEIGEREGKFYAINVPLKDGIDDSSFNRLFRTVV---- 239
Query: 260 EWYQPSAVVLQCGGDSLSGDRLGCFNLSMKGHANCVNYMKSFGVPLMIVGGGGYTMRNVA 319
E YQP A+VLQCG DSL+ DRLGCFNLS+ GHA CV ++K F +PL++ GGGGYT NVA
Sbjct: 240 EIYQPGAIVLQCGADSLARDRLGCFNLSIDGHAECVKFVKKFNLPLLVTGGGGYTKENVA 299
Query: 320 RTWAFETGILNNVIXXXXXXXXXXXXXXXXXXXXXVRPSNMYNVNTPEYLDKVLLNIFSN 379
R W ETGIL + + ++ N+NT Y+ + + I N
Sbjct: 300 RCWTVETGILLDTELPNEIPENDYIKYFAPDFSLKIPGGHIENLNTKSYISSIKVQILEN 359
Query: 380 LEHTKYAPSVQLNHVP 395
L + ++APSVQ+ VP
Sbjct: 360 LRYIQHAPSVQMQEVP 375
>SPAC3G9.07c [B] KOG1342 Histone deacetylase complex catalytic component RPD3
Length = 434
Score = 417 bits (1073), Expect = e-116
Identities = 197/382 (51%), Positives = 262/382 (68%), Gaps = 3/382 (0%)
Query: 17 EKKRVAYFYDADVGNYAYGAGHPMKPHRIRMTHSLIMNYGLYKKMEIYRAKPATKQEMCQ 76
+KKRV Y D VGNY YG HPMKPHRI +T+ L+M YGL+ KM ++ + AT EM +
Sbjct: 24 QKKRVTYHLDEQVGNYHYGDKHPMKPHRITITNHLVMGYGLHNKMSVFSPRMATFGEMSE 83
Query: 77 FHTDEYIDFLSRVTPDNLDMFQKESVKFNVGDDCPVFDGLYEYCSISGGGSMEGAARLNR 136
FH ++Y+DFL RVTPDN + F + +FN+GDDCPVFDG YE+ S G S++ + +L +
Sbjct: 84 FHREDYLDFLKRVTPDNAEQFADKFQQFNIGDDCPVFDGTYEFSQRSAGASLDASRKLVQ 143
Query: 137 GKCDVAINYAGGLHHAKKSEASGFCYLNDIVLGIIELLRYHPRVLYIDIDVHHGDGVEEA 196
G+ D+AIN++GGLHHAK+ EASGFCY+NDIVL I+ +LR+ PRVLYIDID+HHGDGV++A
Sbjct: 144 GQTDIAINWSGGLHHAKRGEASGFCYVNDIVLAILNMLRFFPRVLYIDIDIHHGDGVQQA 203
Query: 197 FYTTDRVMTCSFHKY-GEFFPGTGELRDTGVGKGKYYAVNVPLRDGIDDATYKSVFEPVI 255
FY +DRV+T SFHKY G+FFP TG + GV GKY+A+NVPL DGI D Y S+F+ +I
Sbjct: 204 FYESDRVLTVSFHKYNGDFFPATGNFDENGVKGGKYFALNVPLEDGIGDEQYTSLFKSII 263
Query: 256 GKIMEWYQPSAVVLQCGGDSLSGDRLGCFNLSMKGHANCVNYMKSFGVPLMIVGGGGYTM 315
+ +QPSA+VLQCG DSL DRLG FNLS+ H CV + +SF +P+++VGGGGYT+
Sbjct: 264 EPTINTFQPSAIVLQCGADSLGYDRLGVFNLSIHAHGECVRFTRSFNIPMLVVGGGGYTL 323
Query: 316 RNVARTWAFETGI-LNNVIXXXXXXXXXXXXXXXXXXXXXVR-PSNMYNVNTPEYLDKVL 373
RNVAR W +ET I +N I R + + N NTP+ L+ +
Sbjct: 324 RNVARAWCYETSICVNEQIPSELPRETLYYEFFAPDYTLHPRLTTKIENKNTPKALEDLR 383
Query: 374 LNIFSNLEHTKYAPSVQLNHVP 395
+ L + APSVQ+ +P
Sbjct: 384 IRALEQLRYLGGAPSVQMQQIP 405
>YGL194c [B] KOG1342 Histone deacetylase complex catalytic component RPD3
Length = 452
Score = 404 bits (1038), Expect = e-112
Identities = 183/377 (48%), Positives = 271/377 (71%), Gaps = 4/377 (1%)
Query: 20 RVAYFYDADVGNYAYGAGHPMKPHRIRMTHSLIMNYGLYKKMEIYRAKPATKQEMCQFHT 79
RV+Y +++ V +Y YG HPMKP R+ +T L+ +YGL+K M++Y + AT+ E+ QFH+
Sbjct: 27 RVSYHFNSKVSHYHYGVKHPMKPFRLMLTDHLVSSYGLHKIMDLYETRSATRDELLQFHS 86
Query: 80 DEYIDFLSRVTPDNLDMFQKESVK-FNVGDDCPVFDGLYEYCSISGGGSMEGAARLNRGK 138
++Y++FLS+V+P+N + + +++ FN+GDDCP+F LY+Y ++ G S++ +L +
Sbjct: 87 EDYVNFLSKVSPENANKLPRGTLENFNIGDDCPIFQNLYDYTTLYTGASLDATRKLINNQ 146
Query: 139 CDVAINYAGGLHHAKKSEASGFCYLNDIVLGIIELLRYHPRVLYIDIDVHHGDGVEEAFY 198
D+AIN++GGLHHAKK+ SGFCY+NDIVL I+ LLRYHPR+LYIDID+HHGDGV+EAFY
Sbjct: 147 SDIAINWSGGLHHAKKNSPSGFCYVNDIVLSILNLLRYHPRILYIDIDLHHGDGVQEAFY 206
Query: 199 TTDRVMTCSFHKY-GEFFPGTGELRDTGVGKGKYYAVNVPLRDGIDDATYKSVFEPVIGK 257
TTDRV T SFHKY GEFFPGTG+L + G KGK++A+NVPL DGIDD +Y ++F+ ++
Sbjct: 207 TTDRVFTLSFHKYNGEFFPGTGDLTEIGCDKGKHFALNVPLEDGIDDDSYINLFKSIVDP 266
Query: 258 IMEWYQPSAVVLQCGGDSLSGDRLGCFNLSMKGHANCVNYMKSFGVPLMIVGGGGYTMRN 317
++ ++P+ +V QCG DSL DRLGCFNL++K H CV ++KSFG+P+++VGGGGYT RN
Sbjct: 267 LIMTFKPTLIVQQCGADSLGHDRLGCFNLNIKAHGECVKFVKSFGLPMLVVGGGGYTPRN 326
Query: 318 VARTWAFETGILNNVIX-XXXXXXXXXXXXXXXXXXXXVRPSNMY-NVNTPEYLDKVLLN 375
V+R W +ETGILN+V+ ++Y N N+ + L+ + +
Sbjct: 327 VSRLWTYETGILNDVLLPEDIPEDIPFRDSFGPDYSLYPMLDDLYENKNSKKLLEDIRIR 386
Query: 376 IFSNLEHTKYAPSVQLN 392
N+ + + APSV+++
Sbjct: 387 CLENIRYLQGAPSVRMD 403
>CE01472 [B] KOG1342 Histone deacetylase complex catalytic component RPD3
Length = 507
Score = 382 bits (982), Expect = e-106
Identities = 187/382 (48%), Positives = 253/382 (65%), Gaps = 6/382 (1%)
Query: 17 EKKRVAYFYDADVGNYAYGAGHPMKPHRIRMTHSLIMNYGLYKKMEIYRAKPATKQEMCQ 76
+K+ VAY+Y DVG++ YG HPMKP R+ + + L+++Y + K M + + ++
Sbjct: 27 KKRNVAYYYHKDVGHFHYGQLHPMKPQRLVVCNDLVVSYEMPKYMTVVESPKLDAADISV 86
Query: 77 FHTDEYIDFLSRVTPD-NLDMFQKESVKFNVGDDCPVFDGLYEYCSISGGGSMEGAARLN 135
FHT++Y++FL VTP L M +FN+G+DCP+F GL++YC++ GGS+EGA RLN
Sbjct: 87 FHTEDYVNFLQTVTPKLGLTMPDDVLRQFNIGEDCPIFAGLWDYCTLYAGGSVEGARRLN 146
Query: 136 RGKCDVAINYAGGLHHAKKSEASGFCYLNDIVLGIIELLRYHPRVLYIDIDVHHGDGVEE 195
D+ IN+ GGLHHAKKSEASGFCY+NDIVLGI+ELL+YH RVLYIDID+HHGDGV+E
Sbjct: 147 HKMNDIVINWPGGLHHAKKSEASGFCYVNDIVLGILELLKYHKRVLYIDIDIHHGDGVQE 206
Query: 196 AFYTTDRVMTCSFHKYGEFFPGTGELRDTGVGKGKYYAVNVPLRDGIDDATYKSVFEPVI 255
AF +DRVMT SFH++G++FPG+G + D GVG GKY+A+NVPL I D Y +FE VI
Sbjct: 207 AFNNSDRVMTVSFHRFGQYFPGSGSIMDKGVGPGKYFAINVPLMAAIRDEPYLKLFESVI 266
Query: 256 GKIMEWYQPSAVVLQCGGDSLSGDRLGCFNLSMKGHANCVNYMKSFGVPLMIVGGGGYTM 315
+ E + P A+VLQCG DSL DRLG F LS HA V Y+KS G PLM++GGGGYT+
Sbjct: 267 SGVEENFNPEAIVLQCGSDSLCEDRLGQFALSFNAHARAVKYVKSLGKPLMVLGGGGYTL 326
Query: 316 RNVARTWAFETGILNNVIXXXXXXXXXXXXXXXXXXXXXVRPS---NMYNVNTPEYLDKV 372
RNVAR WA ETG++ + +RP+ M + N+ YL +
Sbjct: 327 RNVARCWALETGVILGL--RMDDEIPGTSLYSHYFTPRLLRPNLVPKMNDANSAAYLASI 384
Query: 373 LLNIFSNLEHTKYAPSVQLNHV 394
+ L + APSVQ+ ++
Sbjct: 385 EKETLACLRMIRGAPSVQMQNI 406
>At5g35600 [B] KOG1342 Histone deacetylase complex catalytic component RPD3
Length = 409
Score = 351 bits (900), Expect = 1e-96
Identities = 179/384 (46%), Positives = 243/384 (62%), Gaps = 10/384 (2%)
Query: 18 KKRVAYFYDADVGNYAYGAGHPMKPHRIRMTHSLIMNYGLYKKMEIYRAKPATKQEMCQF 77
K+RV+YFY+ +G+Y YG P KP RIR+TH+LI++Y L++ MEI A + +F
Sbjct: 9 KRRVSYFYEPMIGDYYYGVNQPTKPQRIRVTHNLILSYNLHRHMEINHPDLADASDFEKF 68
Query: 78 HTDEYIDFLSRVTPDNLD----MFQKESVKFNVGDDC--PVFDGLYEYCSISGGGSMEGA 131
H+ EYI+FL VTP+ + + +FNV D PVF L++YC GGS+ A
Sbjct: 69 HSLEYINFLKSVTPETVTDPHPSVSENLKRFNVDVDWDGPVFHNLFDYCRAYAGGSISAA 128
Query: 132 ARLNRGKCDVAINYAGGLHHAKKSEASGFCYLNDIVLGIIELLRYHPRVLYIDIDVHHGD 191
A+LNR + D+AIN+AGG+HH KK +ASGF Y+ND+VL I+ELL+ RVLYI+I HGD
Sbjct: 129 AKLNRQEADIAINWAGGMHHVKKDKASGFGYVNDVVLAILELLKSFKRVLYIEIGFPHGD 188
Query: 192 GVEEAFYTTDRVMTCSFHKYGEFFPGTGELRDTGVGKGKYYAVNVPLRDGIDDATYKSVF 251
VEEAF TDRVMT SFHK G+ TG++ D G GKG+YY++N PL+DG+DD + + +F
Sbjct: 189 EVEEAFKDTDRVMTVSFHKVGD----TGDISDYGEGKGQYYSLNAPLKDGLDDFSLRGLF 244
Query: 252 EPVIGKIMEWYQPSAVVLQCGGDSLSGDRLGCFNLSMKGHANCVNYMKSFGVPLMIVGGG 311
PVI + ME Y+P +VLQCG DSL+GD G FNLS+KGH +C+ Y++SF VPLMI+GGG
Sbjct: 245 IPVIHRAMEIYEPEVIVLQCGADSLAGDPFGTFNLSIKGHGDCLQYVRSFNVPLMILGGG 304
Query: 312 GYTMRNVARTWAFETGILNNVIXXXXXXXXXXXXXXXXXXXXXVRPSNMYNVNTPEYLDK 371
GYT+ NVAR W +ET I + P+N N+NT +
Sbjct: 305 GYTLPNVARCWCYETAIAVGEQLDNDLPGNDYMKYFRPDYKLHILPTNRQNLNTRLDIIT 364
Query: 372 VLLNIFSNLEHTKYAPSVQLNHVP 395
+ + + L +APSV P
Sbjct: 365 MRETLLAQLSLVMHAPSVPFQDTP 388
>ECU09g0670 [B] KOG1342 Histone deacetylase complex catalytic component RPD3
Length = 344
Score = 312 bits (799), Expect = 7e-85
Identities = 156/310 (50%), Positives = 205/310 (65%), Gaps = 25/310 (8%)
Query: 21 VAYFYDADVGNYAYGAGHPMKPHRIRMTHSLIMNYGLYKKMEIYRAKPATKQEMCQFHTD 80
VAY +D +VG + YG HPMKP R +THSL+ ++GL KKM I + + + +HT+
Sbjct: 3 VAYMFDEEVGLFHYGPRHPMKPFRTVVTHSLVKSFGLDKKMTIVKPEVFP---LSSYHTE 59
Query: 81 EYIDFLSRVTPDNLDMFQKESVKFNVGDDCPVFDGLYEYCSISGGGSMEGAARLNRGKCD 140
EY+ L + N DCP F GL +C + G S+ A L+ G
Sbjct: 60 EYLGNLGK----------------NETPDCPNFIGLPRFCELYGSASINSAMILSEGAYS 103
Query: 141 VAINYAGGLHHAKKSEASGFCYLNDIVLGIIELLRYHPRVLYIDIDVHHGDGVEEAFYTT 200
IN++GGLHHA K+ SGFC++NDIVL I+ELL+ + RV+YIDIDVHHGDGVEEAF
Sbjct: 104 TVINWSGGLHHAHKAIPSGFCHVNDIVLAILELLKTYRRVMYIDIDVHHGDGVEEAFLEC 163
Query: 201 DRVMTCSFHKYGE-FFPGTGELRDTGVGKGKYYAVNVPLRDGIDDATYKSVFEPVIGKIM 259
DRV+T S HKYG+ FFP TG L TG + AVNVPL GIDD +Y+ +FEP++ +
Sbjct: 164 DRVLTLSLHKYGDGFFPETGTLITTG-----HRAVNVPLLSGIDDPSYRYIFEPIVESCV 218
Query: 260 EWYQPSAVVLQCGGDSLSGDRLGCFNLSMKGHANCVNYMKSFGVPLMIVGGGGYTMRNVA 319
+ P A+VLQCG DSL DRLGCFNLS++GHA+CV ++ S G+PL+ +GGGGYT+ NVA
Sbjct: 219 RRFSPDAIVLQCGADSLGEDRLGCFNLSIEGHASCVRFVSSLGIPLLCLGGGGYTLTNVA 278
Query: 320 RTWAFETGIL 329
R WA+ET +L
Sbjct: 279 RCWAYETAVL 288
>Hs8923769 [B] KOG1342 Histone deacetylase complex catalytic component RPD3
Length = 377
Score = 299 bits (765), Expect = 6e-81
Identities = 145/342 (42%), Positives = 211/342 (61%), Gaps = 2/342 (0%)
Query: 42 PHRIRMTHSLIMNYGLYKKMEIYRAKPATKQEMCQFHTDEYIDFLSRVTPDNLDMFQKES 101
P R M HSLI Y L+K+M I + K A+ +EM FHTD Y+ L +V+ + D +S
Sbjct: 35 PKRASMVHSLIEAYALHKQMRIVKPKVASMEEMATFHTDAYLQHLQKVSQEG-DDDHPDS 93
Query: 102 VKFNVGDDCPVFDGLYEYCSISGGGSMEGAARLNRGKCDVAINYAGGLHHAKKSEASGFC 161
+++ +G DCP +G+++Y + GG ++ A L G C VAIN++GG HHAKK EASGFC
Sbjct: 94 IEYGLGYDCPATEGIFDYAAAIGGATITAAQCLIDGMCKVAINWSGGWHHAKKDEASGFC 153
Query: 162 YLNDIVLGIIELLRYHPRVLYIDIDVHHGDGVEEAFYTTDRVMTCSFHKYGE-FFPGTGE 220
YLND VLGI+ L R R+LY+D+D+HHGDGVE+AF T +VMT S HK+ FFPGTG+
Sbjct: 154 YLNDAVLGILRLRRKFERILYVDLDLHHGDGVEDAFSFTSKVMTVSLHKFSPGFFPGTGD 213
Query: 221 LRDTGVGKGKYYAVNVPLRDGIDDATYKSVFEPVIGKIMEWYQPSAVVLQCGGDSLSGDR 280
+ D G+GKG+YY+VNVP++DGI D Y + E V+ ++ + + P AVVLQ G D+++GD
Sbjct: 214 VSDVGLGKGRYYSVNVPIQDGIQDEKYYQICESVLKEVYQAFNPKAVVLQLGADTIAGDP 273
Query: 281 LGCFNLSMKGHANCVNYMKSFGVPLMIVGGGGYTMRNVARTWAFETGILNNVIXXXXXXX 340
+ FN++ G C+ Y+ + + +I+GGGGY + N AR W + TG++
Sbjct: 274 MCSFNMTPVGIGKCLKYILQWQLATLILGGGGYNLANTARCWTYLTGVILGKTLSSEIPD 333
Query: 341 XXXXXXXXXXXXXXVRPSNMYNVNTPEYLDKVLLNIFSNLEH 382
+ PS + N P + ++L I NL+H
Sbjct: 334 HEFFTAYGPDYVLEITPSCRPDRNEPHRIQQILNYIKGNLKH 375
>YPR068c [B] KOG1342 Histone deacetylase complex catalytic component RPD3
Length = 470
Score = 168 bits (425), Expect = 2e-41
Identities = 89/241 (36%), Positives = 144/241 (58%), Gaps = 9/241 (3%)
Query: 91 PDNLDMFQKESVKFNVGDDCPVFDGLYEYCSISGGGSMEGAARLNRGKCDVAINYAGGLH 150
P + + E+ ++N+ DCP+F L YC + G ++ L+ + + IN+ GG H
Sbjct: 151 PTDTYILNSETKQYNLEGDCPIFSYLPMYCQVITGATLNLLDHLSPTERLIGINWDGGRH 210
Query: 151 HAKKSEASGFCYLNDIVLGIIELLRYHP--RVLYIDIDVHHGDGVEEAFYTTDRVMTCSF 208
HA K ASGFCY+ND+VL +I+ LR ++ Y+D D+HHGDGVE+AF + ++ T S
Sbjct: 211 HAFKQRASGFCYINDVVL-LIQRLRKAKLNKITYVDFDLHHGDGVEKAFQYSKQIQTISV 269
Query: 209 HKYGE-FFPGTGELRDTGVGKGKYYAVNVPLRDGIDDATYKSVFEPVIGKIMEWYQPSAV 267
H Y FFPGTG L D+ K VN+PL+ G DD + + ++ ++E ++P A+
Sbjct: 270 HLYEPGFFPGTGSLSDSRKDKN---VVNIPLKHGCDDNYLELIASKIVNPLIERHEPEAL 326
Query: 268 VLQCGGDSLSGDRLGCFNLSMKGHAN-CVNYMKSF-GVPLMIVGGGGYTMRNVARTWAFE 325
+++CGGD L GDR + L+++G + +N MKS+ + ++GGGGY ++R + +
Sbjct: 327 IIECGGDGLLGDRFNEWQLTIRGLSRIIINIMKSYPRAHIFLLGGGGYNDLLMSRFYTYL 386
Query: 326 T 326
T
Sbjct: 387 T 387
>YNL021w [B] KOG1343 Histone deacetylase complex catalytic component HDA1
Length = 706
Score = 127 bits (319), Expect = 3e-29
Identities = 87/327 (26%), Positives = 159/327 (48%), Gaps = 30/327 (9%)
Query: 20 RVAYFYDADVGNYAYGAGHPMKPHRIRMTHSLIMNYGLYKKMEI------------YRAK 67
R+ Y + Y HP P RI + ++ GL + +
Sbjct: 65 RMRYHAKIFTSYFEYIDPHPEDPRRIYRIYKILAENGLINDPTLSGVDDLGDLMLKIPVR 124
Query: 68 PATKQEMCQFHTDEYIDFLSRVTPDNLDMFQKESVKFNVGDDCPVFDGLYEYCSISGGGS 127
AT +E+ + HT E+++F+ + + KE+ K GD + Y + GG+
Sbjct: 125 AATSEEILEVHTKEHLEFIESTEKMSREELLKETEK---GDSVYFNNDSYASARLPCGGA 181
Query: 128 MEGAARLNRG--KCDVAINYAGGLHHAKKSEASGFCYLNDIVLGIIELLRYHP----RVL 181
+E + G K +A+ G HHA+ A GFC +++ + +L+ +P R++
Sbjct: 182 IEACKAVVEGRVKNSLAVVRPPG-HHAEPQAAGGFCLFSNVAVAAKNILKNYPESVRRIM 240
Query: 182 YIDIDVHHGDGVEEAFYTTDRVMTCSFHKY--GEFFPGT--GELRDTGVGKGKYYAVNV- 236
+D D+HHG+G +++FY D+V+ S H++ G+++PGT G+ TG GKG+ + N+
Sbjct: 241 ILDWDIHHGNGTQKSFYQDDQVLYVSLHRFEMGKYYPGTIQGQYDQTGEGKGEGFNCNIT 300
Query: 237 -PLRDGIDDATYKSVFEPVIGKIMEWYQPSAVVLQCGGDSLSGDRLGCFNLSMKGHANCV 295
P+ G+ DA Y FE V+ + ++P V++ G D+ GD +G +++ + +
Sbjct: 301 WPV-GGVGDAEYMWAFEQVVMPMGREFKPDLVIISSGFDAADGDTIGQCHVTPSCYGHMT 359
Query: 296 NYMKSFG-VPLMIVGGGGYTMRNVART 321
+ +KS L +V GGY + +AR+
Sbjct: 360 HMLKSLARGNLCVVLEGGYNLDAIARS 386
>7293057 [B] KOG1343 Histone deacetylase complex catalytic component HDA1
Length = 883
Score = 121 bits (304), Expect = 2e-27
Identities = 88/317 (27%), Positives = 154/317 (47%), Gaps = 26/317 (8%)
Query: 20 RVAYFYDADVGNYAY--GAGHPMKPHRIRMTHSLIMNYGLYKKMEIYRAKPATKQEMCQF 77
+V Y YDA + + GHP +P RI+ H + +YGL K+M+ + AT E+C
Sbjct: 458 KVCYAYDAQMLLHCNLNDTGHPEQPSRIQHIHKMHDDYGLLKQMKQLSPRAATTDEVCLA 517
Query: 78 HTDEYIDFLSRVTPDNLDMFQKESVKFNVGDDCPVFDGLY------EYCSISGGGSMEGA 131
HT +++ + R+ L KE + D +++ +Y + +++ G ++
Sbjct: 518 HTRAHVNTVRRL----LGREPKE-----LHDAAGIYNSVYLHPRTFDCATLAAGLVLQAV 568
Query: 132 ARLNRGKCDVAI-NYAGGLHHAKKSEASGFCYLNDIVLGIIELLRYH--PRVLYIDIDVH 188
+ RG+ I N HHA++ GFC N++ + +R RVL +D DVH
Sbjct: 569 DSVLRGESRSGICNVRPPGHHAEQDHPHGFCIFNNVAIAAQYAIRDFGLERVLIVDWDVH 628
Query: 189 HGDGVEEAFYTTDRVMTCSFHKY--GEFFP--GTGELRDTGVGKGKYYAVNVPL-RDGID 243
HG+G + F + +V+ S H+Y G FFP G G G G+ + VN+P + G+
Sbjct: 629 HGNGTQHIFESNPKVLYISLHRYEHGSFFPKGPDGNFDVVGKGAGRGFNVNIPWNKKGMG 688
Query: 244 DATYKSVFEPVIGKIMEWYQPSAVVLQCGGDSLSGDRLGCFNLSMKGHANCVNYMKSFGV 303
D Y F+ +I I + P V++ G D+ GD LG ++ +G+ +++ +
Sbjct: 689 DLEYALAFQQLIMPIAYEFNPQLVLVSAGFDAAIGDPLGGCKVTAEGYGMLTHWLSALAS 748
Query: 304 PLMIVG-GGGYTMRNVA 319
+IV GGY + +++
Sbjct: 749 GRIIVCLEGGYNVNSIS 765
Score = 104 bits (259), Expect = 3e-22
Identities = 84/322 (26%), Positives = 147/322 (45%), Gaps = 17/322 (5%)
Query: 11 ITVKANEKKRVAYFYDADVGNYA--YGAGHPMKPHRIRMTHSLIMNYGLYKKMEIYRAKP 68
+ K+ +K A YD + + + H P R L ++ ++
Sbjct: 21 VNSKSLVRKPTALIYDESMSQHCCLWDKEHYECPERFTRVLERCRELNLTERCLELPSRS 80
Query: 69 ATKQEMCQFHTDEYIDFLSRVTPDNLDMFQKE-SVKFNVGDDCPVFDGLYEYCSISGGGS 127
ATK E+ + HT+E+ + L + D +E S ++ D + +E ++ G +
Sbjct: 81 ATKDEILRLHTEEHFERLKETSGIRDDERMEELSSRY---DSIYIHPSTFELSLLASGST 137
Query: 128 MEGAARLNRGKCD--VAINYAGGLHHAKKSEASGFCYLNDIVLGIIELLRYHP--RVLYI 183
+E L GK +AI G HHA K+E +G+C+ N++ L L H R+L I
Sbjct: 138 IELVDHLVAGKAQNGMAIIRPPG-HHAMKAEYNGYCFFNNVALATQHALDVHKLQRILII 196
Query: 184 DIDVHHGDGVEEAFYTTDRVMTCSFHKY--GEFFPGTGE--LRDTGVGKGKYYAVNVPLR 239
D DVHHG G + FY RV+ S H++ G F+P E G G G Y NVPL
Sbjct: 197 DYDVHHGQGTQRFFYNDPRVVYFSIHRFEHGSFWPHLHESDYHAIGSGAGTGYNFNVPLN 256
Query: 240 -DGIDDATYKSVFEPVIGKIMEWYQPSAVVLQCGGDSLSGDRLGCFNLSMKGHANCVN-Y 297
G+ + Y ++F+ ++ + +QP +++ G D+ G G ++ + + +N
Sbjct: 257 ATGMTNGDYLAIFQQLLLPVALEFQPELIIVSAGYDAALGCPEGEMEVTPACYPHLLNPL 316
Query: 298 MKSFGVPLMIVGGGGYTMRNVA 319
++ + +V GGY + ++A
Sbjct: 317 LRLADARVAVVLEGGYCLDSLA 338
>At3g18520 [B] KOG1343 Histone deacetylase complex catalytic component HDA1
Length = 561
Score = 114 bits (285), Expect = 3e-25
Identities = 84/301 (27%), Positives = 136/301 (44%), Gaps = 40/301 (13%)
Query: 38 HPMKPHRIRMTHSLIMNYGLYKKMEI-YRAKPATKQEMCQFHTDEYIDFLSRVTPDNLDM 96
HP +P R+R + + G++ + A+ TKQE+ HT E++D + +
Sbjct: 180 HPERPDRLRAIAASLATAGVFPGRCLPINAREITKQELQMVHTSEHVDAVDTTSQLLYSY 239
Query: 97 FQKESVKFNVGDDCPVFDGLYEYCSISGGGSMEGAARLNRGKC-DVAINYAGGL------ 149
F ++ EY + AARL G C D+A + G
Sbjct: 240 FTSDTYA-------------NEYSA--------RAARLAAGLCADLATDIFTGRVKNGFA 278
Query: 150 ------HHAKKSEASGFCYLNDI-VLGIIELLRYHPRVLYIDIDVHHGDGVEEAFYTTDR 202
HHA A GFC N+ V ++ +VL +D DVHHG+G +E F
Sbjct: 279 LVRPPGHHAGVRHAMGFCLHNNAAVAALVAQAAGAKKVLIVDWDVHHGNGTQEIFEQNKS 338
Query: 203 VMTCSFHKY--GEFFPGTGELRDTGVGKGKYYAVNVPLR-DGIDDATYKSVFEPVIGKIM 259
V+ S H++ G F+PGTG + G G+ Y VNVP G+ D Y F+ V+ I
Sbjct: 339 VLYISLHRHEGGNFYPGTGAADEVGSNGGEGYCVNVPWSCGGVGDKDYIFAFQHVVLPIA 398
Query: 260 EWYQPSAVVLQCGGDSLSGDRLGCFNLSMKGHANCVNYMKSF-GVPLMIVGGGGYTMRNV 318
+ P V++ G D+ GD LGC +++ G++ + G ++++ GGY +R++
Sbjct: 399 SAFSPDFVIISAGFDAARGDPLGCCDVTPAGYSRMTQMLGDLCGGKMLVILEGGYNLRSI 458
Query: 319 A 319
+
Sbjct: 459 S 459
>At1g08460 [B] KOG1343 Histone deacetylase complex catalytic component HDA1
Length = 377
Score = 113 bits (282), Expect = 6e-25
Identities = 83/288 (28%), Positives = 130/288 (44%), Gaps = 23/288 (7%)
Query: 38 HPMKPHRIRMTHSLIMNYGLYKKMEIYRAKPATKQEMCQFHTDEYIDFLSRVTPDNLDMF 97
HP R+R S++ + + + PA E+ FHT EYI+ L
Sbjct: 39 HPENADRVRNMLSILRRGPIAPHVNWFTGLPAIVSELLMFHTSEYIEKLVEA-------- 90
Query: 98 QKESVKFNVGDDCPVFDGLYEYCSISGGGSMEGAARLN--RGKCDVAINYAGGLHHAKKS 155
K + + + G +E ++ G ++ + GK A+ G HH++ +
Sbjct: 91 DKSGERCEIAAGTFMSPGSWEAALLAAGTTLSAMQHILDCHGKIAYALVRPPG-HHSQPT 149
Query: 156 EASGFCYLNDIVLGIIELLRYHP--RVLYIDIDVHHGDGVEEAFYTTDRVMTCSFH---- 209
+A G+C+LN+ L + L RV IDIDVH+G+G E FYT+D+V+T S H
Sbjct: 150 QADGYCFLNNAALAVKLALNSGSCSRVAVIDIDVHYGNGTAEGFYTSDKVLTVSLHMNHG 209
Query: 210 KYGEFFPGTGELRDTGVGKGKYYAVNVPLRDGIDDATYKSVFEPVIGKIMEWYQPSAVVL 269
+G P G + + G G Y +NVPL +G D Y+ ++ + + P VVL
Sbjct: 210 SWGSSHPQKGSIDELGEDVGLGYNLNVPLPNGTGDRGYEYAMNELVVPAVRRFGPDMVVL 269
Query: 270 QCGGDSLSGDRLGCFNLSMKGHANCVNYMK------SFGVPLMIVGGG 311
G DS + D G +L+M G+ M+ S G LM+ GG
Sbjct: 270 VVGQDSSAFDPNGRQSLTMNGYRRIGQIMRGVAEEHSHGRLLMVQEGG 317
>Hs5174481 [B] KOG1343 Histone deacetylase complex catalytic component HDA1
Length = 1084
Score = 109 bits (272), Expect = 9e-24
Identities = 97/307 (31%), Positives = 141/307 (45%), Gaps = 44/307 (14%)
Query: 36 AGHPMKPHRIRMTHSLIMNYGLYKKMEIYRAKPATKQEMCQFHTDEYIDFLSRVTPDNLD 95
+ HP RI+ S + GL K E R + AT +E+ H++ + L P N
Sbjct: 673 SSHPEHAGRIQSIWSRLQETGLRGKCECIRGRKATLEELQTVHSEAHT-LLYGTNPLNR- 730
Query: 96 MFQKESVKFNVGDDCPVFDGL------YEYCSISGGGSMEGAARLNRGKCDVAINY---A 146
QK K +G VF L + +I GAARL G C V + +
Sbjct: 731 --QKLDSKKLLGSLASVFVRLPCGGVGVDSDTIWNEVHSAGAARLAVG-CVVELVFKVAT 787
Query: 147 GGL-----------HHAKKSEASGFCYLNDIVLGIIELLRYH---PRVLYIDIDVHHGDG 192
G L HHA++S GFCY N + + +LL+ ++L +D DVHHG+G
Sbjct: 788 GELKNGFAVVRPPGHHAEESTPMGFCYFNSVAVAA-KLLQQRLSVSKILIVDWDVHHGNG 846
Query: 193 VEEAFYTTDRVMTCSFHKY--GEFFPGTGELRDTGVGKGKYYAVNVPLRDGID----DAT 246
++AFY+ V+ S H+Y G FFPG+G + G G G + VN+ G+D DA
Sbjct: 847 TQQAFYSDPSVLYMSLHRYDDGNFFPGSGAPDEVGTGPGVGFNVNMAFTGGLDPPMGDAE 906
Query: 247 YKSVFEPVIGKIMEWYQPSAVVLQCGGDSLSG--DRLGCFNLSMKGHANCVNYMKSFGVP 304
Y + F V+ I + P V++ G D++ G LG +NLS A C Y+
Sbjct: 907 YLAAFRTVVMPIASEFAPDVVLVSSGFDAVEGHPTPLGGYNLS----ARCFGYLTK---Q 959
Query: 305 LMIVGGG 311
LM + GG
Sbjct: 960 LMGLAGG 966
>Hs17158039 [B] KOG1343 Histone deacetylase complex catalytic component HDA1
Length = 1011
Score = 106 bits (265), Expect = 6e-23
Identities = 85/292 (29%), Positives = 135/292 (46%), Gaps = 48/292 (16%)
Query: 38 HPMKPHRIRMTHSLIMNYGLYKKMEIYRAKPATKQEMCQFHTDEYIDFLSRVTPDNLDMF 97
HP RI+ S + GL K E + + A+ +E+ H++ + L P LD
Sbjct: 654 HPEHAGRIQSIWSRLQETGLLNKCERIQGRKASLEEIQLVHSEHH-SLLYGTNP--LDG- 709
Query: 98 QKESVKFNVGDDCPVFDGLYEYCSISGGG------------SMEGAARLNRG-KCDVAIN 144
QK + +GDD F + S+ GG GAAR+ G ++A
Sbjct: 710 QKLDPRILLGDDSQKF-----FSSLPCGGLGVDSDTIWNELHSSGAARMAVGCVIELASK 764
Query: 145 YAGGL------------HHAKKSEASGFCYLNDIVLGIIELLRYH---PRVLYIDIDVHH 189
A G HHA++S A GFC+ N + + + LR ++L +D+DVHH
Sbjct: 765 VASGELKNGFAVVRPPGHHAEESTAMGFCFFNSVAI-TAKYLRDQLNISKILIVDLDVHH 823
Query: 190 GDGVEEAFYTTDRVMTCSFHKY--GEFFPGTGELRDTGVGKGKYYAVNVPLRDGID---- 243
G+G ++AFY ++ S H+Y G FFPG+G + G G G+ Y +N+ G+D
Sbjct: 824 GNGTQQAFYADPSILYISLHRYDEGNFFPGSGAPNEVGTGLGEGYNINIAWTGGLDPPMG 883
Query: 244 DATYKSVFEPVIGKIMEWYQPSAVVLQCGGDSLSGDR--LGCFNLSMK--GH 291
D Y F ++ + + + P V++ G D+L G LG + ++ K GH
Sbjct: 884 DVEYLEAFRTIVKPVAKEFDPDMVLVSAGFDALEGHTPPLGGYKVTAKCFGH 935
>SPBC800.03 [B] KOG1343 Histone deacetylase complex catalytic component HDA1
Length = 687
Score = 105 bits (263), Expect = 1e-22
Identities = 82/302 (27%), Positives = 140/302 (46%), Gaps = 25/302 (8%)
Query: 38 HPMKPHRIRMTHSLIMNYGLYKKM----EIYR---AKPATKQEMCQFHTDEYIDFLSRVT 90
HP P R+ I G + +++ A+ AT +E+ Q H+ E D RVT
Sbjct: 77 HPEDPRRVLRVFEAIKKAGYVSNVPSPSDVFLRIPAREATLEELLQVHSQEMYD---RVT 133
Query: 91 PDNLDMFQKESVKFNVGDDCPVFDGLYEYCS-ISGGGSMEGAARLNRG--KCDVAINYAG 147
+ M ++ D ++ +C+ ++ G ++E + G K A+
Sbjct: 134 -NTEKMSHEDLANLEKISDSLYYNNESAFCARLACGSAIETCTAVVTGQVKNAFAVVRPP 192
Query: 148 GLHHAKKSEASGFCYLNDIVLGIIELLRYHP----RVLYIDIDVHHGDGVEEAFYTTDRV 203
G HHA+ + GFC N++ + +L+ P RVL +D D+HHG+G + AFY V
Sbjct: 193 G-HHAEPHKPGGFCLFNNVSVTARSMLQRFPDKIKRVLIVDWDIHHGNGTQMAFYDDPNV 251
Query: 204 MTCSFHKY--GEFFPGT--GELRDTGVGKGKYYAVNVPLR-DGIDDATYKSVFEPVIGKI 258
+ S H+Y G F+PGT G + G G G VN+P G+ D Y F+ V+ +
Sbjct: 252 LYVSLHRYENGRFYPGTNYGCAENCGEGPGLGRTVNIPWSCAGMGDGDYIYAFQRVVMPV 311
Query: 259 MEWYQPSAVVLQCGGDSLSGDRLGCFNLSMKGHANCVNYMKSFGVPLMIVG-GGGYTMRN 317
+ P V++ CG D+ +GD +G F L+ +A+ + + + GGY + +
Sbjct: 312 AYEFDPDLVIVSCGFDAAAGDHIGQFLLTPAAYAHMTQMLMGLADGKVFISLEGGYNLDS 371
Query: 318 VA 319
++
Sbjct: 372 IS 373
>Hs4885531 [B] KOG1343 Histone deacetylase complex catalytic component HDA1
Length = 1122
Score = 104 bits (260), Expect = 2e-22
Identities = 90/307 (29%), Positives = 135/307 (43%), Gaps = 47/307 (15%)
Query: 38 HPMKPHRIRMTHSLIMNYGLYKKMEIYRAKPATKQEMCQFHTDEYIDFLSRVTPDNLDMF 97
HP RI+ S + GL K E R + AT E+ H+ EY L +P N
Sbjct: 704 HPEHAGRIQSIWSRLQETGLLSKCERIRGRKATLDEIQTVHS-EYHTLLYGTSPLNR--- 759
Query: 98 QKESVKFNVGDDCPVFDGLYEYCSISGGG----------SMEGAARLNRG-KCDVAINYA 146
QK K +G P+ +Y G G A R+ G ++A A
Sbjct: 760 QKLDSKKLLG---PISQKMYAVLPCGGIGVDSDTVWNEMHSSSAVRMAVGCLLELAFKVA 816
Query: 147 GGL------------HHAKKSEASGFCYLNDIVLG--IIELLRYHPRVLYIDIDVHHGDG 192
G HHA++S A GFC+ N + + +++ +VL +D D+HHG+G
Sbjct: 817 AGELKNGFAIIRPPGHHAEESTAMGFCFFNSVAITAKLLQQKLNVGKVLIVDWDIHHGNG 876
Query: 193 VEEAFYTTDRVMTCSFHKY--GEFFPGTGELRDTGVGKGKYYAVNVPLRDGID----DAT 246
++AFY V+ S H+Y G FFPG+G + G G G Y VNV G+D D
Sbjct: 877 TQQAFYNDPSVLYISLHRYDNGNFFPGSGAPEEVGGGPGVGYNVNVAWTGGVDPPIGDVE 936
Query: 247 YKSVFEPVIGKIMEWYQPSAVVLQCGGDSLSG--DRLGCFNLSMKGHANCVNYMKSFGVP 304
Y + F V+ I + P V++ G D++ G LG ++++ A C ++
Sbjct: 937 YLTAFRTVVMPIAHEFSPDVVLVSAGFDAVEGHLSPLGGYSVT----ARCFGHLTR---Q 989
Query: 305 LMIVGGG 311
LM + GG
Sbjct: 990 LMTLAGG 996
>Hs13128864 [B] KOG1343 Histone deacetylase complex catalytic component HDA1
Length = 1215
Score = 101 bits (252), Expect = 2e-21
Identities = 83/330 (25%), Positives = 146/330 (44%), Gaps = 17/330 (5%)
Query: 7 PFDPITVKANEKKRVAYFYDADVGNYA--YGAGHPMKPHRIRMTHSLIMNYGLYKKMEIY 64
P PI + R YD ++ N+ + + HP P RI + GL +
Sbjct: 467 PVLPILTWPVLQSRTGLVYDQNMMNHCNLWDSHHPEVPQRILRIMCRLEELGLAGRCLTL 526
Query: 65 RAKPATKQEMCQFHTDEYIDFLSRVTPDNLDMFQKESVKFNVGDDCPVFDGLYEYCSISG 124
+PAT+ E+ H+ EY+ L +ES F+ CP + ++
Sbjct: 527 TPRPATEAELLTCHSAEYVGHLRATEKMKTRELHRESSNFDSIYICP---STFACAQLAT 583
Query: 125 GGSMEGAARLNRGKC--DVAINYAGGLHHAKKSEASGFCYLNDIVLGI--IELLRYHP-R 179
G + + G+ A+ G HHA++ A GFC+ N + + + + H R
Sbjct: 584 GAACRLVEAVLSGEVLNGAAVVRPPG-HHAEQDAACGFCFFNSVAVAARHAQTISGHALR 642
Query: 180 VLYIDIDVHHGDGVEEAFYTTDRVMTCSFHKY--GEFFPGTGELRDTGVGK--GKYYAVN 235
+L +D DVHHG+G + F V+ S H+Y G FFP E + +G+ G + VN
Sbjct: 643 ILIVDWDVHHGNGTQHMFEDDPSVLYVSLHRYDHGTFFPMGDEGASSQIGRAAGTGFTVN 702
Query: 236 VPLR-DGIDDATYKSVFEPVIGKIMEWYQPSAVVLQCGGDSLSGDRLGCFNLSMKGHANC 294
V + DA Y + + ++ I + P V++ G D+ GD LG +S +G+A+
Sbjct: 703 VAWNGPRMGDADYLAAWHRLVLPIAYEFNPELVLVSAGFDAARGDPLGGCQVSPEGYAHL 762
Query: 295 VNYMKSFGV-PLMIVGGGGYTMRNVARTWA 323
+ + ++++ GGY + +++ + A
Sbjct: 763 THLLMGLASGRIILILEGGYNLTSISESMA 792
Score = 96.3 bits (238), Expect = 8e-20
Identities = 82/294 (27%), Positives = 129/294 (42%), Gaps = 20/294 (6%)
Query: 39 PMKPHRIRMTHSLIMNYGLYKKMEIYRAKPATKQEMCQFHTDEYIDFLSRVTPDNLDMFQ 98
P P R+ ++ GL + ++A+ A K+E+ H+ EYID + N +
Sbjct: 106 PEGPERLHAIKEQLIQEGLLDRCVSFQARFAEKEELMLVHSLEYIDLMETTQYMNEGELR 165
Query: 99 KESVKFNVGDDCPVFDGLYEYCSISGGGSMEGA-----ARLNRGKCDVAINYAGGLHHAK 153
V + D + Y ++ G + A + G +AI G HHA+
Sbjct: 166 ---VLADTYDSVYLHPNSYSCACLASGSVLRLVDAVLGAEIRNG---MAIIRPPG-HHAQ 218
Query: 154 KSEASGFCYLNDIVLGIIELLRYHP--RVLYIDIDVHHGDGVEEAFYTTDRVMTCSFHKY 211
S G+C N + + + H RVL +D DVHHG G + F V+ S H+Y
Sbjct: 219 HSLMDGYCMFNHVAVAARYAQQKHRIRRVLIVDWDVHHGQGTQFTFDQDPSVLYFSIHRY 278
Query: 212 --GEFFP--GTGELRDTGVGKGKYYAVNVPLRD-GIDDATYKSVFEPVIGKIMEWYQPSA 266
G F+P TG G+G+ Y +NVP G+ DA Y + F V+ + +QP
Sbjct: 279 EQGRFWPHLKASNWSTTGFGQGQGYTINVPWNQVGMRDADYIAAFLHVLLPVALEFQPQL 338
Query: 267 VVLQCGGDSLSGDRLGCFNLSMKGHANCVNYMKSF-GVPLMIVGGGGYTMRNVA 319
V++ G D+L GD G + G A + + G L++ GGY +R +A
Sbjct: 339 VLVAAGFDALQGDPKGEMAATPAGFAQLTHLLMGLAGGKLILSLEGGYNLRALA 392
>Hs13259524 [B] KOG1343 Histone deacetylase complex catalytic component HDA1
Length = 912
Score = 100 bits (250), Expect = 3e-21
Identities = 87/310 (28%), Positives = 136/310 (43%), Gaps = 45/310 (14%)
Query: 38 HPMKPHRIRMTHSLIMNYGLYKKMEIYRAKPATKQEMCQFHTDEYI-----DFLSRVTPD 92
HP RI+ S + GL + E R + A+ +E+ H++ ++ + LSR+ D
Sbjct: 501 HPEHAGRIQSIWSRLQERGLRSQCECLRGRKASLEELQSVHSERHVLLYGTNPLSRLKLD 560
Query: 93 NLDMF----QKESVKFNVGDDCPVFDGLYEYCSISGGGSMEGAARLNRGKC-DVAINYAG 147
N + Q+ V G D ++ S AAR G D+A A
Sbjct: 561 NGKLAGLLAQRMFVMLPCGGVGVDTDTIWNELHSSN------AARWAAGSVTDLAFKVAS 614
Query: 148 GL------------HHAKKSEASGFCYLNDIVLGIIELLRYHP--RVLYIDIDVHHGDGV 193
HHA S A GFC+ N + + +L + ++L +D DVHHG+G
Sbjct: 615 RELKNGFAVVRPPGHHADHSTAMGFCFFNSVAIACRQLQQQSKASKILIVDWDVHHGNGT 674
Query: 194 EEAFYTTDRVMTCSFHKY--GEFFPGTGELRDTGVGKGKYYAVNVPLRDGID----DATY 247
++ FY V+ S H++ G FFPG+G + + G G G+ + VNV G+D D Y
Sbjct: 675 QQTFYQDPSVLYISLHRHDDGNFFPGSGAVDEVGAGSGEGFNVNVAWAGGLDPPMGDPEY 734
Query: 248 KSVFEPVIGKIMEWYQPSAVVLQCGGDSLSGD--RLGCFNLSMKGHANCVNYMKSFGVPL 305
+ F V+ I + P V++ G D+ G LG +++S A C YM L
Sbjct: 735 LAAFRIVVMPIAREFSPDLVLVSAGFDAAEGHPAPLGGYHVS----AKCFGYMTQ---QL 787
Query: 306 MIVGGGGYTM 315
M + GG +
Sbjct: 788 MNLAGGAVVL 797
>Hs13259522 [B] KOG1343 Histone deacetylase complex catalytic component HDA1
Length = 952
Score = 100 bits (250), Expect = 3e-21
Identities = 87/310 (28%), Positives = 136/310 (43%), Gaps = 45/310 (14%)
Query: 38 HPMKPHRIRMTHSLIMNYGLYKKMEIYRAKPATKQEMCQFHTDEYI-----DFLSRVTPD 92
HP RI+ S + GL + E R + A+ +E+ H++ ++ + LSR+ D
Sbjct: 541 HPEHAGRIQSIWSRLQERGLRSQCECLRGRKASLEELQSVHSERHVLLYGTNPLSRLKLD 600
Query: 93 NLDMF----QKESVKFNVGDDCPVFDGLYEYCSISGGGSMEGAARLNRGKC-DVAINYAG 147
N + Q+ V G D ++ S AAR G D+A A
Sbjct: 601 NGKLAGLLAQRMFVMLPCGGVGVDTDTIWNELHSSN------AARWAAGSVTDLAFKVAS 654
Query: 148 GL------------HHAKKSEASGFCYLNDIVLGIIELLRYHP--RVLYIDIDVHHGDGV 193
HHA S A GFC+ N + + +L + ++L +D DVHHG+G
Sbjct: 655 RELKNGFAVVRPPGHHADHSTAMGFCFFNSVAIACRQLQQQSKASKILIVDWDVHHGNGT 714
Query: 194 EEAFYTTDRVMTCSFHKY--GEFFPGTGELRDTGVGKGKYYAVNVPLRDGID----DATY 247
++ FY V+ S H++ G FFPG+G + + G G G+ + VNV G+D D Y
Sbjct: 715 QQTFYQDPSVLYISLHRHDDGNFFPGSGAVDEVGAGSGEGFNVNVAWAGGLDPPMGDPEY 774
Query: 248 KSVFEPVIGKIMEWYQPSAVVLQCGGDSLSGD--RLGCFNLSMKGHANCVNYMKSFGVPL 305
+ F V+ I + P V++ G D+ G LG +++S A C YM L
Sbjct: 775 LAAFRIVVMPIAREFSPDLVLVSAGFDAAEGHPAPLGGYHVS----AKCFGYMTQ---QL 827
Query: 306 MIVGGGGYTM 315
M + GG +
Sbjct: 828 MNLAGGAVVL 837
>CE25887 [B] KOG1343 Histone deacetylase complex catalytic component HDA1
Length = 955
Score = 98.6 bits (244), Expect = 2e-20
Identities = 89/332 (26%), Positives = 147/332 (43%), Gaps = 15/332 (4%)
Query: 13 VKANEKKRVAYFYDADVGNYAYGA-GHPMKPHRIRMTHSLIMNYGLYKK-MEIYRAKPAT 70
+ + + YF + D ++ HP KP R R + G+ +K ++ + AT
Sbjct: 420 IPTENMETLIYFNEGDDAHFDLEEDNHPEKPARTRRILKTLRESGVLEKCVDRNCERIAT 479
Query: 71 KQEMCQFHTDEYIDFLSRVTPDNLDMFQKESVKFNVGDDCPVFDGLYEYCSISGG--GSM 128
+E+ HT + ++ L R T D E + D L G S+
Sbjct: 480 NEEIRLVHTKKMLEHL-RTTETMKDEELMEEAEKEFNSIYLTRDTLKVARKAVGAVLQSV 538
Query: 129 EGAARLNRGKCDVAINYAGGLHHAKKSEASGFCYLNDIVLGIIELLRYHP--RVLYIDID 186
+ + G+ + + HHA S++SGFC N++ + R H RVL +D D
Sbjct: 539 DEIFEKDAGQRNALVIVRPPGHHASASKSSGFCIFNNVAVAAKYAQRRHKAKRVLILDWD 598
Query: 187 VHHGDGVEEAFYTTDRVMTCSFHKY--GEFFPGTGELR---DTGVGKGKYYAVNVPLRD- 240
VHHG+G +E FY VM S H++ G F+P GE + D G G G+ +VNVP
Sbjct: 599 VHHGNGTQEIFYEDSNVMYMSIHRHDKGNFYP-IGEPKDYSDVGEGAGEGMSVNVPFSGV 657
Query: 241 GIDDATYKSVFEPVIGKIMEWYQPSAVVLQCGGDSLSGDRLGCFNLSMKGHANCVNYMKS 300
+ D Y+ F+ VI I + P V++ G D+ D LG + ++ + A + S
Sbjct: 658 QMGDNEYQMAFQRVIMPIAYQFNPDLVLISAGFDAAVDDPLGEYKVTPETFALMTYQLSS 717
Query: 301 F-GVPLMIVGGGGYTMRNVARTWAFETGILNN 331
G ++ V GGY + +++ + +L N
Sbjct: 718 LAGGRIITVLEGGYNLTSISNSAQAVCEVLQN 749
Score = 87.4 bits (215), Expect = 4e-17
Identities = 56/171 (32%), Positives = 86/171 (49%), Gaps = 7/171 (4%)
Query: 150 HHAKKSEASGFCYLNDIVLGIIE-LLRYHPRVLYIDIDVHHGDGVEEAFYTTDRVMTCSF 208
HHA GFC N++ E R+L +D+DVHHG G + FY RV+ S
Sbjct: 145 HHADSVSPCGFCLFNNVAQAAEEAFFSGAERILIVDLDVHHGHGTQRIFYDDKRVLYFSI 204
Query: 209 HK--YGEFFPGTGE--LRDTGVGKGKYYAVNVPLRD-GIDDATYKSVFEPVIGKIMEWYQ 263
H+ +G F+P E G GKG Y N+ L + G D+ Y S+ V+ + +
Sbjct: 205 HRHEHGLFWPHLPESDFDHIGSGKGLGYNANLALNETGCTDSDYLSIIFHVLLPLATQFD 264
Query: 264 PSAVVLQCGGDSLSGDRLGCFNLSMKGHANCVNYMKSFGV-PLMIVGGGGY 313
P V++ G D+L GD LG L+ G+++ + ++KS +++V GGY
Sbjct: 265 PHFVIISAGFDALLGDPLGGMCLTPDGYSHILYHLKSLAQGRMLVVLEGGY 315
>CE20772 [B] KOG1343 Histone deacetylase complex catalytic component HDA1
Length = 863
Score = 98.6 bits (244), Expect = 2e-20
Identities = 89/332 (26%), Positives = 147/332 (43%), Gaps = 15/332 (4%)
Query: 13 VKANEKKRVAYFYDADVGNYAYGA-GHPMKPHRIRMTHSLIMNYGLYKK-MEIYRAKPAT 70
+ + + YF + D ++ HP KP R R + G+ +K ++ + AT
Sbjct: 420 IPTENMETLIYFNEGDDAHFDLEEDNHPEKPARTRRILKTLRESGVLEKCVDRNCERIAT 479
Query: 71 KQEMCQFHTDEYIDFLSRVTPDNLDMFQKESVKFNVGDDCPVFDGLYEYCSISGG--GSM 128
+E+ HT + ++ L R T D E + D L G S+
Sbjct: 480 NEEIRLVHTKKMLEHL-RTTETMKDEELMEEAEKEFNSIYLTRDTLKVARKAVGAVLQSV 538
Query: 129 EGAARLNRGKCDVAINYAGGLHHAKKSEASGFCYLNDIVLGIIELLRYHP--RVLYIDID 186
+ + G+ + + HHA S++SGFC N++ + R H RVL +D D
Sbjct: 539 DEIFEKDAGQRNALVIVRPPGHHASASKSSGFCIFNNVAVAAKYAQRRHKAKRVLILDWD 598
Query: 187 VHHGDGVEEAFYTTDRVMTCSFHKY--GEFFPGTGELR---DTGVGKGKYYAVNVPLRD- 240
VHHG+G +E FY VM S H++ G F+P GE + D G G G+ +VNVP
Sbjct: 599 VHHGNGTQEIFYEDSNVMYMSIHRHDKGNFYP-IGEPKDYSDVGEGAGEGMSVNVPFSGV 657
Query: 241 GIDDATYKSVFEPVIGKIMEWYQPSAVVLQCGGDSLSGDRLGCFNLSMKGHANCVNYMKS 300
+ D Y+ F+ VI I + P V++ G D+ D LG + ++ + A + S
Sbjct: 658 QMGDNEYQMAFQRVIMPIAYQFNPDLVLISAGFDAAVDDPLGEYKVTPETFALMTYQLSS 717
Query: 301 F-GVPLMIVGGGGYTMRNVARTWAFETGILNN 331
G ++ V GGY + +++ + +L N
Sbjct: 718 LAGGRIITVLEGGYNLTSISNSAQAVCEVLQN 749
Score = 87.4 bits (215), Expect = 4e-17
Identities = 56/171 (32%), Positives = 86/171 (49%), Gaps = 7/171 (4%)
Query: 150 HHAKKSEASGFCYLNDIVLGIIE-LLRYHPRVLYIDIDVHHGDGVEEAFYTTDRVMTCSF 208
HHA GFC N++ E R+L +D+DVHHG G + FY RV+ S
Sbjct: 145 HHADSVSPCGFCLFNNVAQAAEEAFFSGAERILIVDLDVHHGHGTQRIFYDDKRVLYFSI 204
Query: 209 HK--YGEFFPGTGE--LRDTGVGKGKYYAVNVPLRD-GIDDATYKSVFEPVIGKIMEWYQ 263
H+ +G F+P E G GKG Y N+ L + G D+ Y S+ V+ + +
Sbjct: 205 HRHEHGLFWPHLPESDFDHIGSGKGLGYNANLALNETGCTDSDYLSIIFHVLLPLATQFD 264
Query: 264 PSAVVLQCGGDSLSGDRLGCFNLSMKGHANCVNYMKSFGV-PLMIVGGGGY 313
P V++ G D+L GD LG L+ G+++ + ++KS +++V GGY
Sbjct: 265 PHFVIISAGFDALLGDPLGGMCLTPDGYSHILYHLKSLAQGRMLVVLEGGY 315
>Hs21237799 [B] KOG1343 Histone deacetylase complex catalytic component HDA1
Length = 1037
Score = 95.9 bits (237), Expect = 1e-19
Identities = 57/172 (33%), Positives = 90/172 (52%), Gaps = 17/172 (9%)
Query: 150 HHAKKSEASGFCYLNDIVLG--IIELLRYHPRVLYIDIDVHHGDGVEEAFYTTDRVMTCS 207
HHA++S A GFC+ N + + +++ +VL +D D+HHG+G ++AFY V+ S
Sbjct: 747 HHAEESTAMGFCFFNSVAITAKLLQQKLNVGKVLIVDWDIHHGNGTQQAFYNDPSVLYIS 806
Query: 208 FHKY--GEFFPGTGELRDTGVGKGKYYAVNVPLRDGID----DATYKSVFEPVIGKIMEW 261
H+Y G FFPG+G + G G G Y VNV G+D D Y + F V+ I
Sbjct: 807 LHRYDNGNFFPGSGAPEEVGGGPGVGYNVNVAWTGGVDPPIGDVEYLTAFRTVVMPIAHE 866
Query: 262 YQPSAVVLQCGGDSLSG--DRLGCFNLSMKGHANCVNYMKSFGVPLMIVGGG 311
+ P V++ G D++ G LG ++++ A C ++ LM + GG
Sbjct: 867 FSPDVVLVSAGFDAVEGHLSPLGGYSVT----ARCFGHLTR---QLMTLAGG 911
>CE08062 [B] KOG1343 Histone deacetylase complex catalytic component HDA1
Length = 796
Score = 94.7 bits (234), Expect = 2e-19
Identities = 80/310 (25%), Positives = 141/310 (44%), Gaps = 30/310 (9%)
Query: 36 AGHPMKPHRIRMTHSLIMNYGLYKKMEIYRAKPATKQEMCQFHTDEYIDFLSRVTPDNLD 95
A H RI+ S ++ +G +K E AK A+ +++ H+ Y F + V+P
Sbjct: 411 ASHVENGGRIQSIWSKLIEHGHVQKCEKVTAKKASLEQLQLVHSQTYTTFFA-VSPTACL 469
Query: 96 MFQKESVKFNVGDDCPVFDGLYEYCSISGGGSMEGAARLNRGKC-DVAINYAGGL----- 149
S+ P + + S + AARL G +++ A G
Sbjct: 470 KIDANSLPLKRFLQLPCGGIGVDSDTYFNDASTQTAARLAAGTLIELSSQVAEGRLKNGF 529
Query: 150 -------HHAKKSEASGFCYLNDIVLGIIELLRYHP----RVLYIDIDVHHGDGVEEAFY 198
HHA+ +A GFC+ N++ + + L +P ++ ID DVHHG+G + +F
Sbjct: 530 ACIRPPGHHAEHEQAMGFCFFNNVAVAVKVLQTKYPAQCAKIAIIDWDVHHGNGTQLSFE 589
Query: 199 TTDRVMTCSFHKY--GEFFPGTGELRDTGVGKGKYYAVNVPLR-DGIDDATYKSVFEPVI 255
V+ S H++ G FFPGTG + + G K VNVP D + D Y + + VI
Sbjct: 590 NDPNVLYMSLHRHDKGNFFPGTGSVTEVGKNDAKGLTVNVPFSGDVMRDPEYLAAWRTVI 649
Query: 256 GKIMEWYQPSAVVLQCGGDSLSG--DRLGCFNLS--MKGH--ANCVNYMKSFGVPLMIVG 309
+M + P +++ G D+ G + LG + ++ M G+ + +NY +++
Sbjct: 650 EPVMASFCPDFIIVSAGFDACHGHPNALGGYEVTPEMFGYMTKSLLNYASG---KVVLAL 706
Query: 310 GGGYTMRNVA 319
GGY +++++
Sbjct: 707 EGGYDLKSIS 716
>7292853 [B] KOG1343 Histone deacetylase complex catalytic component HDA1
Length = 1235
Score = 93.6 bits (231), Expect = 5e-19
Identities = 74/266 (27%), Positives = 119/266 (43%), Gaps = 25/266 (9%)
Query: 36 AGHPMKPHRIRMTHSLIMNYGLYKKMEIYRAKPATKQEMCQFHTDEYIDF-------LSR 88
A HP R++ + + L K+ + RA+ AT++E+ HT+ + LSR
Sbjct: 841 AQHPEHSGRLQSVWARLNETDLVKRCDRLRARKATQEELQTVHTEAHAMLFGSNQCQLSR 900
Query: 89 VTPDNLDMFQKESVKFNVGDDCPVFDGLYEYCSISGGGSMEGAA----RLNRGKCDVAIN 144
+N V+ + G D + + M L K D+
Sbjct: 901 PKLENT--LSASFVRLSCGGLGVDLDTTWNEHHTATAARMAAGCVIDLALKTAKGDLRNG 958
Query: 145 YAGGL---HHAKKSEASGFCYLNDIVLGIIELLRYHP---RVLYIDIDVHHGDGVEEAFY 198
+A HHA+ + A GFC+ N I + L + P R+L +D DVHHG+G ++AFY
Sbjct: 959 FAVVRPPGHHAEANLAMGFCFFNSIAIAAKLLRQRMPEVRRILIVDWDVHHGNGTQQAFY 1018
Query: 199 TTDRVMTCSFHKY--GEFFPGTGELRDTGVGKGKYYAVNV----PLRDGIDDATYKSVFE 252
+ ++ S H++ G FFPGTG + G G G + VN+ L + DA Y + F
Sbjct: 1019 QSPDILYLSIHRHDDGNFFPGTGGPTECGSGAGLGFNVNISWSGALNPPLGDAEYIAAFR 1078
Query: 253 PVIGKIMEWYQPSAVVLQCGGDSLSG 278
V+ I + P V++ G D+ +G
Sbjct: 1079 TVVMPIARSFNPDIVLVSSGFDAATG 1104
>CE24411 [B] KOG1343 Histone deacetylase complex catalytic component HDA1
Length = 517
Score = 89.4 bits (220), Expect = 1e-17
Identities = 63/265 (23%), Positives = 115/265 (42%), Gaps = 11/265 (4%)
Query: 60 KMEIYRAKPATKQEMCQFHTDEYIDFLSRVTPDNLDMFQKESVKFNVGDDCPVFDGLYEY 119
++E + A + E+ HT Y+D + ++ + K+ +D V +
Sbjct: 50 RIEHIPRREAEESEILAVHTKRYVDDVKSTETMTVEQQESFCTKY---EDIYVNSATWHR 106
Query: 120 CSISGGGSMEGAARLNRGKCDVAINYAGGLHHAKKSEASGFCYLNDIVLGIIELLRYHPR 179
++ G S++ + K HHA E GFC N++ + ++ +
Sbjct: 107 AKLAAGASIDLMTSVMAAKRPGIAFIRPPGHHAMPDEGCGFCIFNNVAIAAKAAIQNGQK 166
Query: 180 VLYIDIDVHHGDGVEEAF--YTTDRVMTCSFHKY--GEFFPGTGELRDTGVGKGKYYAVN 235
VL +D DVH G+G +E V S H+Y G F+P + TG+ +N
Sbjct: 167 VLIVDYDVHAGNGTQECVEQMGEGNVQLISIHRYENGHFWP---NMPQTGIYHNYKNTIN 223
Query: 236 VPLRD-GIDDATYKSVFEPVIGKIMEWYQPSAVVLQCGGDSLSGDRLGCFNLSMKGHANC 294
+PL G+ DA Y ++F +I + +QP +++ G D+ GD G ++ G A
Sbjct: 224 LPLNTIGLTDADYHALFTHIILPTIHAFQPDLLLVSSGFDASIGDPEGSMQVTPAGFATM 283
Query: 295 VNYMKSFGVPLMIVGGGGYTMRNVA 319
+ + G+P+ + GGY + +A
Sbjct: 284 IRMLIDTGIPVAALLEGGYFLDALA 308
>At5g61060 [B] KOG1343 Histone deacetylase complex catalytic component HDA1
Length = 717
Score = 89.0 bits (219), Expect = 1e-17
Identities = 72/301 (23%), Positives = 127/301 (41%), Gaps = 47/301 (15%)
Query: 13 VKANEKKRVAYFYDADVGNYAY--GAGHPMKPHRIRMTHSLIMNYGLYKKMEIYRAKPAT 70
V N +++V YD + + G HP P RIR+ + G+ ++ + + A
Sbjct: 19 VAGNRQRKVGLIYDETMCKHDTPDGEDHPECPDRIRVIWEKLQLAGVSQRCVVLGSSKAE 78
Query: 71 KQEMCQFHTDEYIDFLSRVTPDNLDM------FQKESVKFNVGDDCPVFDGLYEYCSISG 124
+ + HT ++++ + ++ D Q S+ N G E ++
Sbjct: 79 DKHLQLVHTKDHVNLVKSISTKQKDYRRNRIASQLNSIYLNGGSS--------EAAYLAA 130
Query: 125 GGSMEGAARLNRGK--CDVAINYAGGLHHAKKSEASGFCYLNDIVLGIIELLRYHP---- 178
G ++ A ++ G+ C AI G HHA+ EA GFC N++ + LL P
Sbjct: 131 GSVVKLAEKVAEGELDCGFAIVRPPG-HHAEADEAMGFCLFNNVAVAASFLLNERPDLGV 189
Query: 179 -RVLYIDIDVHHGDGVEEAFYTTDRVMT--------------------CSFHKYGEFFPG 217
++L +D DVHHG+G ++ F+ R T H+YG F+P
Sbjct: 190 KKILIVDWDVHHGNGTQKMFWKDPREPTFYSITPLLDFYAWKVTGNAFLVRHEYGGFYPA 249
Query: 218 --TGELRDTGVGKGKYYAVNVPLRDG-IDDATYKSVFEPVIGKIMEWYQPSAVVLQCGGD 274
G+ G G G+ + +NVP G DA Y + ++ ++ + + P + L G D
Sbjct: 250 GDDGDYNMVGEGPGEGFNINVPWDQGRCGDADYLAAWDHILIPVAREFNPDVIFLSAGFD 309
Query: 275 S 275
+
Sbjct: 310 A 310
>At4g33470 [B] KOG1343 Histone deacetylase complex catalytic component HDA1
Length = 359
Score = 87.4 bits (215), Expect = 4e-17
Identities = 63/226 (27%), Positives = 101/226 (43%), Gaps = 17/226 (7%)
Query: 61 MEIYRAKPATKQEMCQFHTDEYIDFLSRVTPDNLDMFQKESVKFNVGDDCPVF--DGLYE 118
+E+ K AT +++ H Y+ L + +D + F G P + +
Sbjct: 44 LELANFKTATVEDIANVHDKAYVFGLEKA----MDEASDSGLIFIEGSG-PTYATSTVTA 98
Query: 119 YCSISGGG----SMEGAARLNRGKCDVAINYA---GGLHHAKKSEASGFCYLNDIVLGII 171
CS +G G +RL D I +A HHA GFC ++ +
Sbjct: 99 LCSSAGAGMALVDSVVMSRLTINSVDPPIGFALIRPPGHHAVPKGPMGFCVFGNVAIAAR 158
Query: 172 ELLRYH--PRVLYIDIDVHHGDGVEEAFYTTDRVMTCSFHKYGEFFPGTGELRDTGVGKG 229
R H R+ ID DVHHG+G +AF + S H+ G + PGTG++ D G GKG
Sbjct: 159 HAQRTHGLKRIFIIDFDVHHGNGTNDAFTEDPDIFFLSTHQDGSY-PGTGKISDIGKGKG 217
Query: 230 KYYAVNVPLRDGIDDATYKSVFEPVIGKIMEWYQPSAVVLQCGGDS 275
+ +N+PL G D ++VFE +I + ++P +++ G D+
Sbjct: 218 EGTTLNLPLPGGSGDIAMRTVFEEIIVPCAQRFKPDIILVSAGYDA 263
>At3g44490 [B] KOG1342 Histone deacetylase complex catalytic component RPD3
Length = 158
Score = 86.7 bits (213), Expect = 6e-17
Identities = 40/112 (35%), Positives = 59/112 (51%)
Query: 284 FNLSMKGHANCVNYMKSFGVPLMIVGGGGYTMRNVARTWAFETGILNNVIXXXXXXXXXX 343
F++ GHA CV ++K F +PL++ GGGGYT NVAR W ETGIL +
Sbjct: 3 FSMLFTGHAECVKFVKKFNLPLLVTGGGGYTKENVARCWTVETGILLDTELPNEISENDY 62
Query: 344 XXXXXXXXXXXVRPSNMYNVNTPEYLDKVLLNIFSNLEHTKYAPSVQLNHVP 395
+ ++ N+NT Y+ + + I NL + ++APSVQ+ VP
Sbjct: 63 IKYFAPDFSLKIPGGHIENLNTKSYISSIKVQILENLRYIQHAPSVQMQEVP 114
>Hs20070354 [B] KOG1343 Histone deacetylase complex catalytic component HDA1
Length = 669
Score = 85.5 bits (210), Expect = 1e-16
Identities = 72/296 (24%), Positives = 131/296 (43%), Gaps = 24/296 (8%)
Query: 41 KPHRIRMTHSLIMNYGLYKKMEIYRAKPATKQEMCQFHTDEYIDFLSRVTPDNLDMFQKE 100
+P R+ + GL ++ A+ A+++E+ H+ EY+ + + KE
Sbjct: 27 RPERLTAALDRLRQRGLEQRCLRLSAREASEEELGLVHSPEYVSLVRET-----QVLGKE 81
Query: 101 SVKFNVGDDCPVFDGLYEYCSISGGGSMEGAARLNRGKCDVAINYAGGL-------HHAK 153
++ G FD +Y + S + A L + GL HH +
Sbjct: 82 ELQALSGQ----FDAIYFHPSTFHCARLAAGAGLQLVDAVLTGAVQNGLALVRPPGHHGQ 137
Query: 154 KSEASGFCYLNDIVLGIIELLRYHP--RVLYIDIDVHHGDGVEEAFYTTDRVMTCSFHKY 211
++ A+GFC N++ + + H R+L +D DVHHG G++ F V+ S+H+Y
Sbjct: 138 RAAANGFCVFNNVAIAAAHAKQKHGLHRILVVDWDVHHGQGIQYLFEDDPSVLYFSWHRY 197
Query: 212 --GEFFPGTGELRDTGVGKGK--YYAVNVPLRD-GIDDATYKSVFEPVIGKIMEWYQPSA 266
G F+P E VG+G+ + VN+P G+ +A Y + F ++ + + P
Sbjct: 198 EHGRFWPFLRESDADAVGRGQGLGFTVNLPWNQVGMGNADYVAAFLHLLLPLAFEFDPEL 257
Query: 267 VVLQCGGDSLSGDRLGCFNLSMKGHANCVNYMKSF-GVPLMIVGGGGYTMRNVART 321
V++ G DS GD G + + A+ ++ G + V GGY + ++A +
Sbjct: 258 VLVSAGFDSAIGDPEGQMQATPECFAHLTQLLQVLAGGRVCAVLEGGYHLESLAES 313
>Hs13376228 [B] KOG1344 Predicted histone deacetylase
Length = 347
Score = 79.0 bits (193), Expect = 1e-14
Identities = 63/201 (31%), Positives = 82/201 (40%), Gaps = 18/201 (8%)
Query: 123 SGGGSMEGAARLNRGKCDVAINYAGGLHHAKKSEASGFCYLNDIVLGI---IELLRYHPR 179
+GG M G + RG AIN GG HH GFC DI L I E + R
Sbjct: 118 TGGTIMAGKLAVERGW---AINVGGGFHHCSSDRGGGFCAYADITLAIKFLFERVEGISR 174
Query: 180 VLYIDIDVHHGDGVEEAFYTTDRVMTCSFHKYGEFFPGTGELRDTGVGKGKYYAVNVPLR 239
ID+D H G+G E F RV + +PG + K V L
Sbjct: 175 ATIIDLDAHQGNGHERDFMDDKRVYIMDVYNR-HIYPGDRFAKQAIRRK-------VELE 226
Query: 240 DGIDDATYKSVFEPVIGKIMEWYQPSAVVLQCGGDSLSGDRLGCFNLSMKGHAN----CV 295
G +D Y E I K ++ + P VV G D L GDRLG ++S G
Sbjct: 227 WGTEDDEYLDKVERNIKKSLQEHLPDVVVYNAGTDILEGDRLGGLSISPAGIVKRDELVF 286
Query: 296 NYMKSFGVPLMIVGGGGYTMR 316
++ VP+++V GGY R
Sbjct: 287 RMVRGRRVPILMVTSGGYQKR 307
>Hs17158041 [B] KOG1343 Histone deacetylase complex catalytic component HDA1
Length = 879
Score = 76.6 bits (187), Expect = 7e-14
Identities = 64/212 (30%), Positives = 98/212 (46%), Gaps = 40/212 (18%)
Query: 38 HPMKPHRIRMTHSLIMNYGLYKKMEIYRAKPATKQEMCQFHTDEYIDFLSRVTPDNLDMF 97
HP RI+ S + GL K E + + A+ +E+ H++ + L P LD
Sbjct: 654 HPEHAGRIQSIWSRLQETGLLNKCERIQGRKASLEEIQLVHSEHH-SLLYGTNP--LDG- 709
Query: 98 QKESVKFNVGDDCPVFDGLYEYCSISGGG------------SMEGAARLNRG-KCDVAIN 144
QK + +GDD F + S+ GG GAAR+ G ++A
Sbjct: 710 QKLDPRILLGDDSQKF-----FSSLPCGGLGVDSDTIWNELHSSGAARMAVGCVIELASK 764
Query: 145 YAGGL------------HHAKKSEASGFCYLNDIVLGIIELLRYH---PRVLYIDIDVHH 189
A G HHA++S A GFC+ N + + + LR ++L +D+DVHH
Sbjct: 765 VASGELKNGFAVVRPPGHHAEESTAMGFCFFNSVAI-TAKYLRDQLNISKILIVDLDVHH 823
Query: 190 GDGVEEAFYTTDRVMTCSFHKY--GEFFPGTG 219
G+G ++AFY ++ S H+Y G FFPG+G
Sbjct: 824 GNGTQQAFYADPSILYISLHRYDEGNFFPGSG 855
>At5g61070 [B] KOG1343 Histone deacetylase complex catalytic component HDA1
Length = 714
Score = 76.3 bits (186), Expect = 9e-14
Identities = 70/332 (21%), Positives = 138/332 (41%), Gaps = 63/332 (18%)
Query: 42 PHRIRMTHSLIMNYGLYKKMEIYRAKPATKQEMCQFHTDEYIDFLSRVTPDNLDMFQKES 101
P RIR+ + G+ ++ + A + + HT ++++ + ++ D ++
Sbjct: 83 PDRIRVIWEKLQLAGVTQRCVVLGGSKAEDKHLKLVHTKKHVNLVKSISTKKKDS-RRNK 141
Query: 102 VKFNVGDDCPVFDGLYEYCSISGGGSMEGAARLNRGK--CDVAINYAGGLHHAKKSEASG 159
+ + D + G E ++ G ++ A ++ G+ C AI G HHA+ EA G
Sbjct: 142 IASQL-DSIYLNGGSSEAAYLAAGSVVKVAEKVAEGELDCGFAIVRPPG-HHAESDEAMG 199
Query: 160 FCYLNDIVLGIIELL-----------------------------------------RYHP 178
FC N++ + LL R P
Sbjct: 200 FCLFNNVAVAASFLLNERVMTSFDFCDAFSISYLLSNFFGHIPLVRTFVLMLCGINRMQP 259
Query: 179 -----RVLYIDIDVHHGDGVEEAFYTTDRVMTCSFHKYGEFFP--GTGELRDTGVGKGKY 231
++L +D D+HHG+ AF T H +G F+P G+ G G G+
Sbjct: 260 DLDVKKILIVDWDIHHGNVTGNAFVTR--------HDHGSFYPFGDDGDFNMVGEGPGEG 311
Query: 232 YAVNVPL-RDGIDDATYKSVFEPVIGKIMEWYQPSAVVLQCGGDSLSGDRLGCFNLSMKG 290
+ +NVP + G DA Y +V+ ++ + + ++P ++L G D+ GD LG ++ G
Sbjct: 312 FNINVPWEQGGCGDADYLAVWNHILIPVTKEFKPDIILLSAGFDAAIGDPLGGCCVTPYG 371
Query: 291 HANCVNYMKSFGVPLMIVG-GGGYTMRNVART 321
++ + + F +++ GGY + ++ ++
Sbjct: 372 YSVMLKKLMEFAHGKIVLALEGGYNLESLGKS 403
>7301219 [B] KOG1344 Predicted histone deacetylase
Length = 343
Score = 72.0 bits (175), Expect = 2e-12
Identities = 74/297 (24%), Positives = 116/297 (38%), Gaps = 28/297 (9%)
Query: 31 NYAYGAG-----HPMKPHRIRMTHSLIMNYGLYKKMEIYRAKPATKQEMCQFHTDEYIDF 85
NYA G HP + + H L+ Y TK ++ + HT EY+
Sbjct: 39 NYAVRFGGLERLHPFDAAKGKHIHKLLCAQLQLDDGSFYEPTELTKDQLRRIHTREYLKS 98
Query: 86 LSRVTPDNLDMFQKESVKFNVGDDCPVFDGLYEYCSISGGGSMEGAARLNRGKCDVAINY 145
L N+ + + V + L + G + G L+ G AIN
Sbjct: 99 LRWSM--NVACIAEVPLMAFVPNRYIQRSYLRPMRFQAAGSILAGKLALDYGW---AINL 153
Query: 146 AGGLHHAKKSEASGFCYLNDIVLGIIELLRYHP----RVLYIDIDVHHGDGVEEAFYTTD 201
GG HH GFC DI L I+ L P R++ +D+D H G+G E F
Sbjct: 154 GGGFHHCCSYRGGGFCPYADISLLIVRLFEQEPFRVRRIMIVDLDAHQGNGHERDFNNVA 213
Query: 202 RVMTCSFHKYGEF-FPGTGELRDTGVGKGKYYAVNVPLRDGIDDATYKSVFEPVIGKIME 260
V F Y F +P +++ V LR+ +D Y + + + +
Sbjct: 214 AVYI--FDMYNAFVYPRDHVAKES-------IRCAVELRNYTEDGFYLRQLKRCLMQSLA 264
Query: 261 WYQPSAVVLQCGGDSLSGDRLGCFNLSMKGHAN----CVNYMKSFGVPLMIVGGGGY 313
++P VV G D L GD LG +S +G + ++ G+P++++ GGY
Sbjct: 265 EFRPDMVVYNAGTDVLEGDPLGNLAISAEGVIERDRLVFSTFRALGIPVVMLLSGGY 321
>At5g26040 [B] KOG1344 Predicted histone deacetylase
Length = 316
Score = 59.7 bits (143), Expect = 8e-09
Identities = 52/188 (27%), Positives = 75/188 (39%), Gaps = 16/188 (8%)
Query: 142 AINYAGGLHHAKKSEASGFCYLNDIVLGI-IELLRYH-PRVLYIDIDVHHGDGVEEAFYT 199
AIN GG HH GFC DI L I LR RV+ ID+D H G+G E
Sbjct: 122 AINIGGGFHHCTAERGGGFCAFADISLCIHFAFLRLRISRVMIIDLDAHQGNGHETDL-- 179
Query: 200 TDRVMTCSFHKYGEFFPGTGELRDTGVGKGKYYAVNVPLRDGIDDATYKSVFEPVIGKIM 259
D +++ + F R ++ V + G Y + +
Sbjct: 180 GDDILSMLAFEVRCIFLQDYRAR-------RFIDQKVEVMSGTTTDEYLRKLDEALEVAS 232
Query: 260 EWYQPSAVVLQCGGDSLSGDRLGCFNLSMKG----HANCVNYMKSFGVPLMIVGGGGYTM 315
+QP V+ G D L GD LG +S G + + +PL+++ GGY M
Sbjct: 233 RNFQPELVIYNAGTDILDGDPLGLLKISPDGITSRDEKVFRFAREKNIPLVMLTSGGY-M 291
Query: 316 RNVARTWA 323
++ AR A
Sbjct: 292 KSSARVIA 299
>CE20787 [B] KOG1343 Histone deacetylase complex catalytic component HDA1
Length = 782
Score = 59.3 bits (142), Expect = 1e-08
Identities = 50/183 (27%), Positives = 81/183 (43%), Gaps = 15/183 (8%)
Query: 118 EYCSISGGGSMEGAARLNRGKCD---VAINYAGGLHHAKKSEASGFCYLNDIVLGI---I 171
E ++ GGS+E GK + G HH+ A G+C N++ + I
Sbjct: 374 EAARVAIGGSIELVKAAMEGKIHNGFAMVRPPG--HHSYGKVAQGYCIFNNVAIAAKYAI 431
Query: 172 ELLRYHPRVLYIDIDVHHGDGVEEAFYTTDRVMTCSFH--KYGEFFPGTGELRDTGVGKG 229
E L +V +D D H G+G ++ R+ SFH +G F+P + RD
Sbjct: 432 EKLEVK-KVAIVDFDYHAGNGTYQSVKDESRIHLTSFHGHHFGAFWPFS---RDYDYATN 487
Query: 230 KYYAVNVPLRDGID-DATYKSVFEPVIGKIMEWYQPSAVVLQCGGDSLSGDRLGCFNLSM 288
+ VPL ++ + Y SVF V+ ++E +QP +++ G DS D + F +
Sbjct: 488 SQNTLFVPLNGTMNSEGDYVSVFHHVLLPMLEQFQPELILISAGFDSGYYDVMMEFGQGV 547
Query: 289 KGH 291
K H
Sbjct: 548 KAH 550
>At3g44660 [B] KOG1342 Histone deacetylase complex catalytic component RPD3
Length = 142
Score = 57.0 bits (136), Expect = 5e-08
Identities = 33/112 (29%), Positives = 47/112 (41%), Gaps = 16/112 (14%)
Query: 284 FNLSMKGHANCVNYMKSFGVPLMIVGGGGYTMRNVARTWAFETGILNNVIXXXXXXXXXX 343
F++ GHA C GGYT NVAR W ETGIL +
Sbjct: 3 FSMLFTGHAEC----------------GGYTKENVARCWTVETGILLDTELPNEIPENDY 46
Query: 344 XXXXXXXXXXXVRPSNMYNVNTPEYLDKVLLNIFSNLEHTKYAPSVQLNHVP 395
+ ++ N+NT Y+ + + I NL + ++APSVQ+ VP
Sbjct: 47 IKYFAPDFSLKIPGGHIENLNTKSYISSIKVQILENLRYIQHAPSVQMQEVP 98
Database: KOG eukaryal database 04/03
Posted date: Apr 14, 2003 1:07 PM
Number of letters in database: 30,389,216
Number of sequences in database: 60,738
Lambda K H
0.321 0.140 0.431
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 25,674,559
Number of Sequences: 60738
Number of extensions: 1117259
Number of successful extensions: 2030
Number of sequences better than 1.0e-05: 49
Number of HSP's better than 0.0 without gapping: 22
Number of HSP's successfully gapped in prelim test: 27
Number of HSP's that attempted gapping in prelim test: 1891
Number of HSP's gapped (non-prelim): 63
length of query: 432
length of database: 30,389,216
effective HSP length: 109
effective length of query: 323
effective length of database: 23,768,774
effective search space: 7677314002
effective search space used: 7677314002
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)