ORF STATUS Function Best COG Functional category Pathways and functional systems
r_klactV0573 good I KOG1888 Lipid transport and metabolism Putative phosphoinositide phosphatase
Only best alignment is shown:
BLASTP 2.2.3 [May-13-2002]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= r_klactV0573 199797 197200 -866
(866 letters)
Database: KOG eukaryal database 04/03
60,738 sequences; 30,389,216 total letters
Searching..................................................done
Color Key for Alignment Scores: 
Score E
Sequences producing significant alignments: (bits) Value
YNL325c [I] KOG1888 Putative phosphoinositide phosphatase 1027 0.0
Hs7662034 [I] KOG1888 Putative phosphoinositide phosphatase 477 e-134
7295697 [I] KOG1888 Putative phosphoinositide phosphatase 413 e-115
CE08566 [I] KOG1888 Putative phosphoinositide phosphatase 376 e-104
At3g43220 [I] KOG1888 Putative phosphoinositide phosphatase 314 3e-85
At1g17340 [I] KOG1888 Putative phosphoinositide phosphatase 298 2e-80
At1g22620 [I] KOG1888 Putative phosphoinositide phosphatase 281 2e-75
At5g20840 [I] KOG1888 Putative phosphoinositide phosphatase 252 2e-66
CE09807 [I] KOG1889 Putative phosphoinositide phosphatase 228 4e-59
7292047 [I] KOG1889 Putative phosphoinositide phosphatase 200 7e-51
SPBC19F5.03 [I] KOG1889 Putative phosphoinositide phosphatase 193 8e-49
Hs7662338 [I] KOG1889 Putative phosphoinositide phosphatase 185 2e-46
YKL212w [I] KOG1889 Putative phosphoinositide phosphatase 180 7e-45
YNL106c [U] KOG0566 Inositol-145-triphosphate 5-phosphatase (syn... 164 4e-40
YOR109w [U] KOG0566 Inositol-145-triphosphate 5-phosphatase (syn... 163 9e-40
At5g66020 [I] KOG1889 Putative phosphoinositide phosphatase 162 3e-39
SPBC2G2.02 [U] KOG0566 Inositol-145-triphosphate 5-phosphatase (... 152 2e-36
At3g51830 [I] KOG1889 Putative phosphoinositide phosphatase 152 2e-36
7300754 [I] KOG1890 Phosphoinositide phosphatase SAC1 152 2e-36
CE20170 [I] KOG1890 Phosphoinositide phosphatase SAC1 142 3e-33
At3g51460 [I] KOG1889 Putative phosphoinositide phosphatase 140 1e-32
Hs4507335 [U] KOG0566 Inositol-145-triphosphate 5-phosphatase (s... 138 3e-32
Hs7662414 [I] KOG1890 Phosphoinositide phosphatase SAC1 135 3e-31
7291368 [U] KOG0566 Inositol-145-triphosphate 5-phosphatase (syn... 135 4e-31
CE29050 [U] KOG0566 Inositol-145-triphosphate 5-phosphatase (syn... 123 1e-27
CE28239 [U] KOG0566 Inositol-145-triphosphate 5-phosphatase (syn... 123 1e-27
ECU03g1160 [I] KOG1889 Putative phosphoinositide phosphatase 120 1e-26
Hs14747866 [U] KOG0566 Inositol-145-triphosphate 5-phosphatase (... 117 8e-26
At3g59770 [I] KOG1888 Putative phosphoinositide phosphatase 94 7e-19
SPBC577.13 [U] KOG0566 Inositol-145-triphosphate 5-phosphatase (... 91 6e-18
ECU08g1420 [U] KOG0566 Inositol-145-triphosphate 5-phosphatase (... 84 7e-16
SPAC3C7.01c [I] KOG1889 Putative phosphoinositide phosphatase 75 3e-13
YIL002c [U] KOG0566 Inositol-145-triphosphate 5-phosphatase (syn... 62 4e-09
>YNL325c [I] KOG1888 Putative phosphoinositide phosphatase
Length = 879
Score = 1027 bits (2655), Expect = 0.0
Identities = 526/852 (61%), Positives = 627/852 (72%), Gaps = 47/852 (5%)
Query: 17 TKQRKTMKFTLSKYTIYETKKSIYIVASNKRETMFRILEIDLNGEEDNLNIAEDNVFFMR 76
+KQRKT KF + KYT+YETK +YIV SNKRETMFRILEIDL L + EDNVFF R
Sbjct: 20 SKQRKTSKFVMGKYTLYETKDRMYIVGSNKRETMFRILEIDLTVPRGELTVLEDNVFFTR 79
Query: 77 NEVMEVLRKIEEADDDAXXXXXXXXXXXXVIRFTACYYLVVITEMSQVAVLGGHSIYHID 136
NE+M VL +EEA +D I+FT YYL+++T+ SQVAV+GGH IYHID
Sbjct: 80 NEIMNVLASLEEATEDGLHKKITGYGLLGFIKFTCWYYLIMVTKYSQVAVIGGHGIYHID 139
Query: 137 DTELVPITKSTKK--RDSTELRFIQSFQNLKLSKTFYFSYTFDITNTLQTNILRQKFLSV 194
+++PIT + KK + S E R + F++L L+KTFYFSYT+DITNTLQTNILR+K +V
Sbjct: 140 GIDIIPITNNYKKPEKSSDEARLLNIFKDLDLTKTFYFSYTYDITNTLQTNILREKLKAV 199
Query: 195 GRSDIEVPPGIPDYNEMFMWNSYLLDPIFSCIDTVYDWFQPIIHGFIDQVNVSLFGKSIY 254
R DI +P GI DYNEMF+WN+ LL PIF+CIDTV+DWFQ IIHGFIDQVNVS+ GKSIY
Sbjct: 200 DRCDITIPCGITDYNEMFVWNNNLLSPIFACIDTVFDWFQCIIHGFIDQVNVSVLGKSIY 259
Query: 255 ITLIGRRSHYFAGARFLKRGVNNKGYVANEVETEQIVADMSLTSFHSPARGFFDSDKYTS 314
ITLI RRSH+FAGARFLKRGVNNKG+VANEVETEQIV DM LT FH P GFFDSD+YTS
Sbjct: 260 ITLIARRSHHFAGARFLKRGVNNKGHVANEVETEQIVTDMILTPFHQPGNGFFDSDRYTS 319
Query: 315 FVQHRGSIPLFWSQEASNLTAKPPISINITDPFYSAAAKHFDKLFQRYGGGTIQILNLIK 374
FVQHRGSIPL+W+Q+ASNLT KPPI IN+ DPF+S AA HFD LFQRYGGGTIQILNLIK
Sbjct: 320 FVQHRGSIPLYWTQDASNLTTKPPIRINVVDPFFSPAALHFDNLFQRYGGGTIQILNLIK 379
Query: 375 TKEKNPRETKLGEEFERCIKYLNQFLPDIKKLEYKAWDMSKASKSHGQMVIEFLEKYAKE 434
TKEK PRETKL EFE+CI YLN+FLP +KKL+Y +WDMS+ASK GQ VIEFLEKYA
Sbjct: 380 TKEKTPRETKLLWEFEQCIDYLNEFLPTLKKLDYTSWDMSRASKQDGQGVIEFLEKYAVN 439
Query: 435 TVETTGIFHNGKDFQSTSVQEGVCRTNCIDCLDRTNAAQFVIGKRALGEQLHAMGIIEEK 494
TV TTGIFHNG DF ST +QEG+CR+NCIDCLDRTNAAQFVIGKRALG QL ++GII+
Sbjct: 440 TVTTTGIFHNGPDFASTKIQEGICRSNCIDCLDRTNAAQFVIGKRALGCQLKSLGIIDNS 499
Query: 495 FLEYDSDIVNILTELFHDHGDTIALQYGGSHLVNTMETYRKINQWSSHSRDMVESIKRFY 554
+LEYDSDIVNILTELFHD GDTIALQYGGSHLVNTMETYRKINQWSSHSRDM+ESIKRFY
Sbjct: 500 YLEYDSDIVNILTELFHDLGDTIALQYGGSHLVNTMETYRKINQWSSHSRDMIESIKRFY 559
Query: 555 SNSFVDAQRQEAINLFLGHYIWSKDQPMLWDMSTDFYLHNLYEISGLRRSYRHWWLDSNI 614
SNSFVDAQRQ+AINLFLGHY W + P LW+M+TDFYLHN Y ++ +RSY HWW D NI
Sbjct: 560 SNSFVDAQRQDAINLFLGHYSWREGFPSLWEMNTDFYLHNAYSLNMPKRSYIHWWNDYNI 619
Query: 615 KGLHKTIQEEIIDKNNDVTVAKIFKNVRGYPNSYDNYWNEHYTPRIFVSLKDAFTFNMNS 674
K + + I EE+I NDVT KI KNVRGYP ++DNYWNE+Y PR ++D F +NMNS
Sbjct: 620 KSVKELINEELIATGNDVTREKIIKNVRGYPGAFDNYWNEYYLPRSVTWIRDLFAYNMNS 679
Query: 675 TRRYHHG----KQAISPFDSRKQTSINQKLRLLTS----DKKDKHVSETSRKKVEASVSP 726
TRRYH+ +A+SPF SRKQ+ +N KL+++TS +K + V ET+ ++ SP
Sbjct: 680 TRRYHNALSKQDKAMSPFTSRKQSWLNNKLKMITSSKSLEKAEGRVVETT--DLDRDTSP 737
Query: 727 KDELNLYTAQLKEILHQSEKSLKQLDNFPIG-FPVFSS-------------DQPL----- 767
K EL LY L I +S+K +++++F +P+F S +PL
Sbjct: 738 KQELELYEHYLHIISDRSQKLEEKMNSFSYSKYPIFISHESSEIPPMRKVIGEPLVDIAE 797
Query: 768 SYHEFAIDDDDEIPEYGHTTFEC--NEYDRISNLQKNTRYAYAEPSEETLYENVINFENY 825
+ + DDDD E T E D +S +E YE V+N ++Y
Sbjct: 798 DFTDVYDDDDDGDDENDEMTTEALLIAPDHVS-------------VDEKFYEKVLNVDDY 844
Query: 826 K-LLYDYSEYIN 836
K L DYS I+
Sbjct: 845 KPALDDYSAVIH 856
>Hs7662034 [I] KOG1888 Putative phosphoinositide phosphatase
Length = 907
Score = 477 bits (1227), Expect = e-134
Identities = 282/760 (37%), Positives = 417/760 (54%), Gaps = 75/760 (9%)
Query: 26 TLSKYTIYETKKSIYIVASNKRETMFRILEIDLNGEEDNLNIAEDNVFFMRNEVMEVLRK 85
++ K +YET+ ++V SN ET +R+L+ID +D L I +D + + EV E+L +
Sbjct: 11 SVQKLVLYETRARYFLVGSNNAETKYRVLKIDRTEPKD-LVIIDDRHVYTQQEVRELLGR 69
Query: 86 IE--------EADDDAXXXXXXXXXXXXVIRFTACYYLVVITEMSQVAVLGGHSIYHIDD 137
++ + +RF YY+V+IT+ ++A +GGH+IY ++D
Sbjct: 70 LDLGNRTKMGQKGSSGLFRAVSAFGVVGFVRFLEGYYIVLITKRRKMADIGGHAIYKVED 129
Query: 138 TELVPITK-STKKRDSTELRFIQSFQNLKLSKTFYFSYTFDITNTLQTNIL--------- 187
T ++ I S + E R+++ FQN+ LS FYFSY++D++++LQ N+
Sbjct: 130 TNMIYIPNDSVRVTHPDEARYLRIFQNVDLSSNFYFSYSYDLSHSLQYNLTVLRMPLEML 189
Query: 188 -------RQKFLSVGRSDIEVPPG-------IPDYNEMFMWNSYLLDPIFSCIDTVYDWF 233
RQ+ + + + G + ++WN LLD I S + DW
Sbjct: 190 KSEMTQNRQESFDIFEDEGLITQGGSGVFGICSEPYMKYVWNGELLDIIKSTVHR--DWL 247
Query: 234 QPIIHGFIDQVNVSLFGKSIYITLIGRRSHYFAGARFLKRGVNNKGYVANEVETEQIVAD 293
IIHGF Q + ++G+ +Y+TLI RRS FAG RFLKRG N +G VANEVETEQI+ D
Sbjct: 248 LYIIHGFCGQSKLLIYGRPVYVTLIARRSSKFAGTRFLKRGANCEGDVANEVETEQILCD 307
Query: 294 MSLTSFHSPARGFFDSDKYTSFVQHRGSIPLFWSQEASNLTAKPPISINITDPFYSAAAK 353
S+ SF + Y+S+VQ RGS+PL+WSQ+ S + KPPI+++ DPF AA
Sbjct: 308 ASVMSF--------TAGSYSSYVQVRGSVPLYWSQDISTMMPKPPITLDQADPFAHVAAL 359
Query: 354 HFDKLFQRYGGGTIQILNLIKTKEKNPRETKLGEEFERCIKYLNQFLPDIKKLEYKAWDM 413
HFD++FQR+G I ILNL+K +EK E L EE + YLNQFLP + Y WDM
Sbjct: 360 HFDQMFQRFGSPII-ILNLVKEREKRKHERILSEELVAAVTYLNQFLPPEHTIVYIPWDM 418
Query: 414 SKASKSHGQMVIEFLEKYAKETVETTGIFHNGKD-------------------FQSTSVQ 454
+K +KS V++ L A+ V+ TG F N D + +Q
Sbjct: 419 AKYTKSKLCNVLDRLNVIAESVVKKTGFFVNRPDSYCSILRPDEKWNELGGCVIPTGRLQ 478
Query: 455 EGVCRTNCIDCLDRTNAAQFVIGKRALGEQLHAMGIIEEKFLEYDSDIVNILTELFHDHG 514
G+ RTNC+DCLDRTN AQF++GK AL QL+++G+I++ L++D+D V + EL+ DHG
Sbjct: 479 TGILRTNCVDCLDRTNTAQFMVGKCALAYQLYSLGLIDKPNLQFDTDAVRLFEELYEDHG 538
Query: 515 DTIALQYGGSHLVNTMETYRKINQWSSHSRDMVESIKRFYSNSFVDAQRQEAINLFLGHY 574
DT++LQYGGS LV+ ++TYRKI W+ HS+D+++++ R+YSN+F DA RQ++INLFLG +
Sbjct: 539 DTLSLQYGGSQLVHRVKTYRKIAPWTQHSKDIMQTLSRYYSNAFSDADRQDSINLFLGVF 598
Query: 575 IWSKDQPMLWDMSTDFYLH--NLYEISGLRRSYRHWWLDSNIKGLHKTIQEEIIDKNNDV 632
++ +P LW++ TDFYLH N + RRSY +WW IK L E I N
Sbjct: 599 HPTEGKPHLWELPTDFYLHHKNTMRLLPTRRSYTYWWTPEVIKHLPLPYDEVICAVNLKK 658
Query: 633 TVAKIFKNVRGYPNSYDNYWNEHYTPRIFVSLKDAFTFNMNSTRRYHHGKQA---ISPFD 689
+ K F Y D + NE + P S D F M S+ R K SPF
Sbjct: 659 LIVKKFHK---YEEEIDIH-NEFFRPYELSSFDDTFCLAMTSSARDFMPKTVGIDPSPFT 714
Query: 690 SRKQTSINQKLRLLTSDKKDKHVSETSRKKVEASVSPKDE 729
RK + + +K ++ + RK ++ P E
Sbjct: 715 VRKPDETGKS---VLGNKSNREEAVLQRKTAASAPPPPSE 751
>7295697 [I] KOG1888 Putative phosphoinositide phosphatase
Length = 858
Score = 413 bits (1062), Expect = e-115
Identities = 256/762 (33%), Positives = 398/762 (51%), Gaps = 61/762 (8%)
Query: 26 TLSKYTIYETKKSIYIVASNKRETMFRILEIDLNGEEDNLNIAEDNVFFMRNEVMEVLRK 85
++ K +YET+ +Y+V SN RET FR+L ID + L+I E+ F E+ +
Sbjct: 16 SIQKVVLYETRARLYLVGSNNRETRFRLLTIDRLAH-NRLSIEENANEFNSLEIRRFVAS 74
Query: 86 IEEADDDAXXXXXXXXXXXXVIRFTACYYLVVITEMSQVAVLGGHSIYHIDDTELVPITK 145
+ + +RF YYL+++T+ A +G H +Y I DT +V + +
Sbjct: 75 LSGSPK-----VTSAYGVLGFVRFLEGYYLLLVTKRKCCAHIGRHLVYTIKDTVMVRVNE 129
Query: 146 STKKRDST--ELRFIQSFQNLKLSKTFYFSYTFDITNTLQTNILRQKFLSVGRSDIEVPP 203
T +R E R+ + FQN+ L FYFSY++D+T TLQ N +++ + D++
Sbjct: 130 VTSQRPPHPHEDRYKRMFQNIDLRSNFYFSYSYDLTRTLQYNESAPRYVGA-KVDLDRDE 188
Query: 204 GIPDYNEM----------------------FMWNSYLLDPIFSCIDTVYDWFQPIIHGFI 241
+PD+N + F+WN+YLL P+ + + DW + HGF+
Sbjct: 189 PLPDWNTLTSNVDKAHERVDYAFRSDSRKRFVWNAYLLQPMEGIM--LKDWLLEVTHGFV 246
Query: 242 DQVNVSLFGKSIYITLIGRRSHYFAGARFLKRGVNNKGYVANEVETEQIVADMSLTSFHS 301
Q +S+FG+ + + L+ RRS FAG RFLKRG N +G VANEVETEQIV+D
Sbjct: 247 SQSCISIFGRHVNVCLVARRSSRFAGTRFLKRGANFQGDVANEVETEQIVSD-------- 298
Query: 302 PARGFFDSDKYTSFVQHRGSIPLFWSQEASNLTAKPPISINITDPFYSAAAKHFDKLFQR 361
+ +F Q RGSIP WSQ+ S + KP I ++I DP+ + HF++L
Sbjct: 299 -------GQRICAFTQMRGSIPSHWSQDISKMVPKPQIQLDICDPYAQTPSLHFERLLFH 351
Query: 362 YGGGTIQILNLIKTKEKNPRETKLGEEFERCIKYLNQFLPDIKKLEYKAWDMSKASKSHG 421
YG I +LNL+K +E+ E+ + +E E I+YLNQFLP ++++ +DM++ S+ G
Sbjct: 352 YGAPLI-MLNLVKKRERRKHESIISKELEYSIRYLNQFLPPPHRMKHIHFDMARQSRLSG 410
Query: 422 QMVIEFLEKYAKETVETTGIFHNGKDFQSTSVQEGVCRTNCIDCLDRTNAAQFVIGKRAL 481
V+E L +A+ V+ TG+F + +Q G+ RTNC+DCLDRTN+AQF IGK AL
Sbjct: 411 GNVMEQLAIHAESIVQMTGMFFKAAGSEP-GLQTGIVRTNCVDCLDRTNSAQFAIGKCAL 469
Query: 482 GEQLHAMGIIEEKFLEYDSDIVNILTELFHDHGDTIALQYGGSHLVNTMETYRKINQWSS 541
G QL +G ++ LE+DSD V +L L+ +HGDT+ALQYGGS LV+ ++TYRK W S
Sbjct: 470 GHQLERLGFVKSAKLEFDSDCVTMLENLYEEHGDTLALQYGGSQLVHRIKTYRKTAPWGS 529
Query: 542 HSRDMVESIKRFYSNSFVDAQRQEAINLFLGHY--IWSKDQPMLWDMSTDFYLHNLYEIS 599
D+++++ R+YSN+F D ++Q +INLFLG Y +K P +W++ TD+ +HN +
Sbjct: 530 QGSDVMQTLSRYYSNTFSDTEKQHSINLFLGIYKPSLTKQGPPIWELQTDYDMHNAFVPR 589
Query: 600 GLRRSYRHWWLDSNIKGLHKTIQEEIIDKNNDVTVAKIFKNVRGYPNSYDNYWNEHYTPR 659
++ W + + D N V ++F+ D Y N H + +
Sbjct: 590 ADSKAITDWVRHK----VRACLPYSCADSNK--LVKELFRVHSSGLEMIDAYSNYHQSFK 643
Query: 660 -IFVSLKDAFTFNMNSTRRYHHGKQAISPFDSRKQTSINQKLR-LLTSDKKDKHVSETSR 717
S AF + + R + SPF + QTS + +T ++ S
Sbjct: 644 WTDFSEHIAFEISQLALRYMPTFRTNFSPFQRQIQTSRKARQNPSMTGQSSTGSMNSNSS 703
Query: 718 KKVEASVSPKDELNLYTAQLKEILHQSEKSLKQLDNFPIGFP 759
E S DE L + ++ +Q+E + G P
Sbjct: 704 SSSEGDDSSSDE-ELSASFAEKEANQTESTEPAAATLATGLP 744
>CE08566 [I] KOG1888 Putative phosphoinositide phosphatase
Length = 921
Score = 376 bits (966), Expect = e-104
Identities = 231/630 (36%), Positives = 345/630 (54%), Gaps = 61/630 (9%)
Query: 23 MKFTLSKYTIYETKKSIYIVASNKRETMFRILEIDLNGEEDNLNIAEDNVFFMRNEVMEV 82
M L K T+YETK YI+ + + + +L+ID + L E + R E++E+
Sbjct: 1 MPCRLRKITVYETKSRFYIIGCDSTGSRYNVLKID-RIDPKALITGEPEYDYTREEILEL 59
Query: 83 LRKIEEADDDAXXXXXXXXXXXXVI-------------RFTACYYLVVITEMSQVAVLGG 129
L I + +I RF YYL++IT VA LG
Sbjct: 60 LATISDGSSVVYRSSSKKGTKSGLIERATNAFGILGCVRFVEGYYLIIITRAHAVATLGY 119
Query: 130 HSIYHIDDTELVPITKSTKKRDSTELRFIQSFQNLKLSKTFYFSYTFDITNTLQTNILRQ 189
H +Y I + ++PI S E ++++ FQ++ LS FYFSY++D++ T Q N LR
Sbjct: 120 HPVYKIVEVAMIPIAMDGVSTSSEEQKYVKLFQSVDLSTDFYFSYSYDMSRTFQENSLRS 179
Query: 190 KFLSVGRSDIEVPPGIPDYNEMFMWNSYLLDPIFSCIDTVYDWFQPIIHGFIDQVNVSLF 249
+ + G+ +E +E F+WNS+LL+P+ + + WF I+HG++ Q + L
Sbjct: 180 DWNNHGQRRLEA-------DERFVWNSFLLEPLRKNLISER-WFVEIVHGYVRQEYIFLP 231
Query: 250 GKSIYITLIGRRSHYFAGARFLKRGVNNKGYVANEVETEQIVADMSLTSFHSPARGFFDS 309
I +T+IGRRS +AG RFLKRG N G VAN VETEQIV DM+ + G
Sbjct: 232 IGRISLTIIGRRSTKYAGTRFLKRGANPTGNVANYVETEQIVWDMA-------SSGNVAD 284
Query: 310 DKYTSFVQHRGSIPLFWSQEASN--LTAKPPISINITDPFYSAAAKHFDKLFQRYGGGTI 367
+++SFVQ RGS+P+ WSQ+ S + KP I I+ +P AA HF + +YG I
Sbjct: 285 GRFSSFVQMRGSVPMRWSQDPSTRGVVGKPLILIDNHEPHAQTAASHFRDVRNKYGN-PI 343
Query: 368 QILNLIKTKEKNPRETKLGEEFERCIKYLNQFLPDIKKLEYKAWDMSKASKSHGQM---- 423
I+NLIK EK E L +F + I+YLNQFLP+ +KL Y ++D+++ +K+ M
Sbjct: 344 VIMNLIKRNEKRRHEGVLHTQFLKNIEYLNQFLPNEEKLCYISFDVARCNKAANSMPSIN 403
Query: 424 VIEFLEKYAKETVETTGIF----------------------HNGKDFQSTSVQEGVCRTN 461
V+ +E + +++ G F H+ KD + +Q G+CRTN
Sbjct: 404 VLNVMEDLSMKSILKNGWFQSFPLSEALKIRPREAFATLDAHHSKDGRFM-IQHGICRTN 462
Query: 462 CIDCLDRTNAAQFVIGKRALGEQLHAMGIIEEKFLEYDSDIVNILTELFHDHGDTIALQY 521
C+DCLDRTN AQFVI K ALG QL AMGI++E L S++ +L ++F +HGDT+ALQY
Sbjct: 463 CVDCLDRTNVAQFVIAKVALGCQLCAMGILDEPNLTLQSEVCRLLEDMFDEHGDTMALQY 522
Query: 522 GGSHLVNTMETYRKINQWSSHSRDMVESIKRFYSNSFVDAQRQEAINLFLGHY-IWSKDQ 580
GS LV++++TY+K + RD+ +++ R+YSN+F D +Q AINLFLG +
Sbjct: 523 AGSQLVHSIKTYKKTAAFQERRRDVFQTLSRYYSNTFNDWDKQMAINLFLGVFRPRITTM 582
Query: 581 PMLWDMSTDFYLHNLYEISGLRRSYRHWWL 610
LWD+++D+ LH Y + + Y W L
Sbjct: 583 KNLWDLTSDYNLHFPYSLK-INTDYCAWTL 611
>At3g43220 [I] KOG1888 Putative phosphoinositide phosphatase
Length = 794
Score = 314 bits (805), Expect = 3e-85
Identities = 206/632 (32%), Positives = 327/632 (51%), Gaps = 97/632 (15%)
Query: 16 ATKQRKTMKFTLSKYTIYETKKSIYIVASNKRETMFRILEIDLNGEEDNLNIAEDNVFFM 75
+T T +L ++ ++ET+ + Y++ + ++R+L+ID + LNI++D+ +
Sbjct: 4 STDDAGTTTHSLQEFKLFETQSNFYMIGWDG-SGVYRVLKID-RLDPSELNISQDSTHYT 61
Query: 76 RNEVMEVLRKIEEADDDAXXXXXXXXXXXXV--IRFTACYYLVVITEMSQVAVLGGHSIY 133
+ E E+L++I E + + ++F YY+++ITE + L GHS+Y
Sbjct: 62 KKECYELLKRIHEGNKATGGLKLVTLCYGIIGFVKFLGPYYMLLITERRHIGDLFGHSVY 121
Query: 134 HIDDTELVPITKSTKKRDSTELRFIQSFQNLKLSKTFYFSYTFDITNTLQTNILRQKFLS 193
+ +E+V + ST + + F N + SY++++ + Q N+ +
Sbjct: 122 AVSKSEIVALHNSTVQCN---------FANSRDEN----SYSYNVMRSYQKNVCNYE--- 165
Query: 194 VGRSDIEVPPGIPDYNEMFMWNSYLLDPIFSCIDTVYDWFQPIIHGFIDQVNVSLFGKSI 253
G Y +MF+WN +L I + W +++GF Q ++S GK
Sbjct: 166 ---------TGHNLYEKMFVWNEFLTRGIRHHLRNTL-WTVALVYGFFKQASLSESGKDF 215
Query: 254 YITLIGRRSHYFAGARFLKRGVNNKGYVANEVETEQIVADMSLTSFHSPARGFFDSDKYT 313
ITLI RRS + AG R+LKRGVN G VAN+VETEQIV++ + H + +
Sbjct: 216 KITLIARRSRHNAGTRYLKRGVNRNGDVANDVETEQIVSE-DVPEDHPM--------QIS 266
Query: 314 SFVQHRGSIPLFWSQEASNLTAKPPISINITDPFYSAAAKHFDKLFQRYGGGTIQILNLI 373
S VQ+RGSIPLFWSQE S L KP I ++ +P Y A HFD L +RYG I ILNLI
Sbjct: 267 SVVQNRGSIPLFWSQETSRLNLKPDIVLSKKEPNYEATRLHFDNLVERYGNPII-ILNLI 325
Query: 374 KTKEKNPRETKLGEEFERCIKYLNQFLPDIKKLEYKAWDMSKASKSHGQMVIEFLEKYAK 433
KTKE+ PRE+ L EEF I ++N+ LP+ +L + WD+ K +S + V+ L K A
Sbjct: 326 KTKERRPRESILREEFVNAIDFINKDLPEENRLRFLHWDLHKHFRSKTKNVLALLCKVAT 385
Query: 434 ETVETTGIFH-----------------------------------NG-------KDFQST 451
+ T +F+ NG K +S
Sbjct: 386 CALMLTDLFYYQVTPAMTIEDSMSLSSSSDADTGDISPHTSSDDDNGDHDSLEKKSSRSK 445
Query: 452 SV------------QEGVCRTNCIDCLDRTNAAQFVIGKRALGEQLHAMGIIEEKFLEYD 499
++ Q GV RTNCIDCLDRTN AQ+ G ALG+QLH +GI + +E D
Sbjct: 446 NIAYGKCDVKPPRLQSGVLRTNCIDCLDRTNVAQYAYGWAALGQQLHVLGIRDVPAIELD 505
Query: 500 SDIVNILTELFHDHGDTIALQYGGSHLVNTMETYRKINQW--SSHSRDMVESIKRFYSNS 557
+ L L+ GDT+A QYGGS N + + R+ QW ++ S++ + +++R+Y+N+
Sbjct: 506 DPLAISLMGLYERMGDTLAHQYGGSAAHNKVFSERR-GQWRAATQSQEFLRTLQRYYNNA 564
Query: 558 FVDAQRQEAINLFLGHYIWSKDQPMLWDMSTD 589
++DA +Q+AIN+FLG + + P +W++ ++
Sbjct: 565 YMDADKQDAINIFLGTFQPEQGMPAIWELRSN 596
>At1g17340 [I] KOG1888 Putative phosphoinositide phosphatase
Length = 802
Score = 298 bits (763), Expect = 2e-80
Identities = 218/682 (31%), Positives = 347/682 (49%), Gaps = 85/682 (12%)
Query: 27 LSKYTIYETKKSI----------YIVASNKRETMFRILEIDLNGEEDNLNIAEDNVFFMR 76
L K+ +Y T I Y++ ++ ++ RIL+ID +++ LN+ ED + +
Sbjct: 19 LQKFKLYATPSVISSSFDLTPNFYLIGRDENKSFRRILKIDRR-DQNELNLFEDPTRYTK 77
Query: 77 NEVMEVLRKIEEADDDAXXXXXXXXXXXXV--IRFTACYYLVVITEMSQVAVLGGHSIYH 134
+E+ E+ R++ ++++ + +RF YY+++IT+ +V + GH++Y
Sbjct: 78 DEMRELKRRMIVGNEESGGFKAITTCYGIIGFVRFLEPYYMLLITKRKKVGEICGHTVYG 137
Query: 135 IDDTELV----PITKSTKKRDSTELRFIQSFQNLKLSKTFYFSYTFDITNTLQTNILRQK 190
I +++++ P +S + ELR+ + + LSK FYFSYT+ + +LQ NI
Sbjct: 138 IAESQMIAIPHPSIQSKVAKSEAELRYKKLLSVVDLSKNFYFSYTYHLMYSLQKNI---- 193
Query: 191 FLSVGRSDIEVPPGIPDYNEMFMWNSYLLDPIFSCIDTVYDWFQPIIHGFIDQVNVSLFG 250
G ++ G P N MF+WNS+L I + W +I+GF Q S+ G
Sbjct: 194 ----GNTE----RGNPHDNTMFVWNSFLTREIRKILQNSI-WTVALIYGFFQQTKCSVSG 244
Query: 251 KSIYITLIGRRSHYFAGARFLKRGVNNKGYVANEVETEQIVADMSLTSFHSPARGFFDSD 310
+ T+I RRS ++AG R RGVN+ G VAN+VETEQIV+ + P
Sbjct: 245 EKFVFTIIARRSRHYAGTR---RGVNDIGRVANDVETEQIVSKVVPAGQKIPI------- 294
Query: 311 KYTSFVQHRGSIPLFWSQEASNLTAKPPISINITDPFYSAAAKHFDKLFQRYGGGTIQIL 370
TS VQ RGSIPLFWSQEAS +P I +N D Y A HF L QRYG I IL
Sbjct: 295 --TSVVQVRGSIPLFWSQEASVFNPQPEIILNKKDANYEATQHHFQNLRQRYGNRII-IL 351
Query: 371 NLIK--TKEKNPRETKLGEEFERCIKYLNQFLPDIKKLEYKAWDMSKASKSHGQMV---- 424
NL+K T EK RET L EF + I+++N+ + +L+ +D+SK K +
Sbjct: 352 NLLKTVTGEKKHRETILRGEFAKTIRFINKGMDREHRLKAIHFDLSKHYKKYCIYAPYWK 411
Query: 425 -IEFLEKY--------AKETVETTGIFHN---GKDFQSTS------------VQEGVCRT 460
+E + + E V F+N +D +++S +Q GV RT
Sbjct: 412 SLELTDLFYCKAPSGVGAEEVIYDSFFNNPIPSQDEEASSPEKEDMKADIFLLQNGVLRT 471
Query: 461 NCIDCLDRTNAAQFVIGKRALGEQLHAMGIIEEKFLEYDSDIVNILTELFHDHGDTIALQ 520
NCIDCLDRTN AQ+ G +LG QL +GI ++ ++ + L + + G+T+A+Q
Sbjct: 472 NCIDCLDRTNFAQYAHGLVSLGHQLRTLGISGPPVVDLNNPLAIELMDAYQKMGNTLAMQ 531
Query: 521 YGGSHLVNTMETYRKINQWS--SHSRDMVESIKRFYSNSFVDAQRQEAINLFLGHYIWSK 578
YGGS + M + N W+ RD+ +++R+YSN++ D+ +Q AIN+FLGH+
Sbjct: 532 YGGSEAHSKMFCDLRGN-WNMVMRQRDIFTAVRRYYSNAYQDSDKQNAINVFLGHFRPRL 590
Query: 579 DQPMLWDMSTDFYLHNL------YEISGLRRSYRHWWLDSNIKGLHKTIQEEIIDKNNDV 632
+P LW++ +D HN+ +I +R R + D+ I + EE++ +N+
Sbjct: 591 GRPALWELDSD--QHNIGRSGSNLDIENMRPLIRRSFSDNIIMDCDLNL-EELVRENSQP 647
Query: 633 TVAKIFKNVRGYPNSYDNYWNE 654
T + V G + Y E
Sbjct: 648 TYEGLNGGVSGTNLEFPFYETE 669
>At1g22620 [I] KOG1888 Putative phosphoinositide phosphatase
Length = 925
Score = 281 bits (720), Expect = 2e-75
Identities = 164/437 (37%), Positives = 244/437 (55%), Gaps = 40/437 (9%)
Query: 25 FTLSKYTIYETKKSIYIVASNKRETMFRILEIDLNGEEDNLNIAEDNVFFMRNEVMEVLR 84
+ L K+ +YET+ Y+V S++ + FR+L+ID E LNI+ED V + E+ +L+
Sbjct: 32 YALEKFKLYETRARFYLVGSDRNKRFFRVLKID-RSEPSELNISEDPVVYSPQEIKSLLQ 90
Query: 85 KIEEAD--DDAXXXXXXXXXXXXVIRFTACYYLVVITEMSQVAVLGGHSIYHIDDTELVP 142
+I E + +F YYLV++T+ Q+ + GH+IY ID+++++
Sbjct: 91 RIAEGNRATGGLAFVAKVYGIAGCAKFMESYYLVLVTKRRQIGCICGHAIYAIDESQMIS 150
Query: 143 ITKSTKKRD----STELRFIQSFQNLKLSKTFYFSYTFDITNTLQTNILRQKFLSVGRSD 198
+ +T + D TELR+ + ++ L+K F++SYT+ I +LQ N+L S G
Sbjct: 151 VPHATIQSDVANSKTELRYKKLLSSVDLTKDFFYSYTYPIMQSLQKNVL-----SSGEE- 204
Query: 199 IEVPPGIPDYNEMFMWNSYLLDPIFS-CIDTVYDWFQPIIHGFIDQVNVSLFGKSIYITL 257
G+P Y+ +F+WNSYL PI S C +T+ W ++HG Q+ +S++G+ +TL
Sbjct: 205 -----GMP-YDNIFVWNSYLTQPIRSRCNNTI--WTLALVHGHFKQIRLSIYGRDFSVTL 256
Query: 258 IGRRSHYFAGARFLKRGVNNKGYVANEVETEQIVADMSLTSFHSPARGFFDSDKYTSFVQ 317
+ RRS +FAG R+LKRGVN++G VAN+VETEQ+V D S K +S VQ
Sbjct: 257 VSRRSRHFAGTRYLKRGVNDRGRVANDVETEQLVLDDEAGSC---------KGKMSSVVQ 307
Query: 318 HRGSIPLFWSQEASNLTAKPPISINITDPFYSAAAKHFDKLFQRYGGGTIQILNLIKTK- 376
RGSIPLFWSQEAS + KP I + DP Y + HF+ L RYG I +LNLIKT
Sbjct: 308 MRGSIPLFWSQEASRFSPKPDIFLQRYDPTYESTKMHFEDLVNRYGNPII-VLNLIKTNI 366
Query: 377 -------EKNPRETKLGEEFERCIKYLNQFLPDIKKLEYKAWDMSKASKSHGQMVIEFLE 429
EK PRE L EF + YLN + L++ WD K +KS V+ L
Sbjct: 367 HGNIQTVEKRPREMVLRREFANAVGYLNSIFREENHLKFIHWDFHKFAKSKSANVLAVLG 426
Query: 430 KYAKETVETTGIFHNGK 446
A E ++ TG++ +GK
Sbjct: 427 AVASEALDLTGLYFSGK 443
Score = 146 bits (369), Expect = 1e-34
Identities = 76/195 (38%), Positives = 119/195 (60%), Gaps = 5/195 (2%)
Query: 401 PDIKKLEYKAWDMSKASKSHGQMVIEFLEKYAKETVETTGIFHNGKDFQSTSVQEGVCRT 460
P ++ L + ++S+ ++ ++ L KE T G + + Q GV RT
Sbjct: 468 PSLRDLRAYSAELSRGESAND--ILSALANREKEMKLTQQKKDEGTNSSAPRYQSGVLRT 525
Query: 461 NCIDCLDRTNAAQFVIGKRALGEQLHAMGIIEEKFLEYDSDIVNILTELFHDHGDTIALQ 520
NCIDCLDRTN AQ+ G ALG QLHAMG+ + ++ DS I L +++ GD +A Q
Sbjct: 526 NCIDCLDRTNVAQYAYGLAALGRQLHAMGLSDTPKIDPDSSIAAALMDMYQSMGDALAQQ 585
Query: 521 YGGSHLVNTMETYRKINQW--SSHSRDMVESIKRFYSNSFVDAQRQEAINLFLGHYIWSK 578
YGGS NT+ R+ +W ++ SR+ ++SIKR+YSN++ D ++Q+AINLFLG++ +
Sbjct: 586 YGGSAAHNTVFPERQ-GKWKATTQSREFLKSIKRYYSNTYTDGEKQDAINLFLGYFQPQE 644
Query: 579 DQPMLWDMSTDFYLH 593
+P LW++ +D+YLH
Sbjct: 645 GKPALWELDSDYYLH 659
>At5g20840 [I] KOG1888 Putative phosphoinositide phosphatase
Length = 774
Score = 252 bits (643), Expect = 2e-66
Identities = 175/550 (31%), Positives = 262/550 (46%), Gaps = 108/550 (19%)
Query: 27 LSKYTIYETKKSIYIVASNKRETMFRILEIDLNGEEDNLNIAEDNVFFMRNEVMEVLRKI 86
+ ++ ++ET+ + Y++ N ++RIL+ID E LN+ ED+ + + E E+L++I
Sbjct: 24 MQQFKLFETQANFYMIGWNG-SGVYRILKID-RLEASELNLREDSTAYTKKECYELLKRI 81
Query: 87 EEADDDAXXXXXXXXXXXXV--IRFTACYYLVVITEMSQVAVLGGHSIYHIDDTELVPIT 144
E + + I+F YY+++ITE ++ + GH +Y + ++++ +
Sbjct: 82 HEGNKATGGLKLVTVCYGIIGFIKFLGPYYMLLITERREIGEICGHIVYEVSKSDMIALQ 141
Query: 145 KSTKKRDSTELRFIQSFQNLKLSKTFYFSYTFDITNTLQTNILRQKFLSVGRSDIEVPPG 204
S+ ++ LR SFQ NI + G
Sbjct: 142 HSSVLCNTANLRDENSFQK---------------------NICDHE------------SG 168
Query: 205 IPDYNEMFMWNSYLLDPIFSCIDTVYDWFQPIIHGFIDQVNVSLFGKSIYITLIGRRSHY 264
Y +MF+WN +L + W +++GF Q +S G++ +TLI RRS +
Sbjct: 169 GTLYKKMFVWNEFLTRGTRHHLRNTL-WTVALVYGFFKQTILSEAGRNFKLTLIARRSRH 227
Query: 265 FAGARFLKRGVNNKGYVANEVETEQIVADMSLTSFHSPARGFFDSDKYTSFVQHRGSIPL 324
AG R+LKRG+N G VAN+VETEQIV++ P + +S VQ+RGSIPL
Sbjct: 228 NAGTRYLKRGINESGNVANDVETEQIVSED--VPVDRPM-------QISSVVQNRGSIPL 278
Query: 325 FWSQEASNLTAKPPISINITDPFYSAAAKHFDKLFQRYGGGTIQILNLIKTKEKNPRETK 384
FWSQE S + KP I+ + HF+ L +RYG I ILNLIKT E+ PRE+
Sbjct: 279 FWSQETSRMKVKPDIATRV----------HFENLVERYGVPII-ILNLIKTNERKPRESI 327
Query: 385 LGEEFERCIKYLNQFLPDIKKLEYKAWDMSKASKSHGQMVIEFLEKYAKETVETTGIF-- 442
L EF I ++N+ LP+ +L + WD+ K S + V+ L K A + TG F
Sbjct: 328 LRAEFANAIDFINKDLPEENRLRFLHWDLHKHFHSKTENVLALLGKVAACALMLTGFFYY 387
Query: 443 -----------------------HNGKDFQS-------------------------TSVQ 454
HN D S + +Q
Sbjct: 388 QLTPAMKLEGYMSLSSSDADTSPHNSSDDDSRDYDSLEKNCRPSKNVANGDYDVKPSRLQ 447
Query: 455 EGVCRTNCIDCLDRTNAAQFVIGKRALGEQLHAMGIIEEKFLEYDSDIVNILTELFHDHG 514
GV RTNCIDCLDRTN AQ+ G ALG+QLHA+GI + +E D + + L L+ G
Sbjct: 448 SGVLRTNCIDCLDRTNVAQYAYGWAALGQQLHALGIRDAPTIELDDPLSSTLMGLYERMG 507
Query: 515 DTIALQYGGS 524
DT+A QYGGS
Sbjct: 508 DTLAYQYGGS 517
>CE09807 [I] KOG1889 Putative phosphoinositide phosphatase
Length = 591
Score = 228 bits (580), Expect = 4e-59
Identities = 164/489 (33%), Positives = 254/489 (51%), Gaps = 38/489 (7%)
Query: 107 IRFTACYYLVVITEMSQVAVLGGHSIYHIDDTELVPITKSTKKRDSTELRFIQSFQNLKL 166
I+ + Y L+VIT+ S + + H+I+ I D E++P K+T ++R+ + F ++
Sbjct: 69 IKLVSGYALIVITKASLIGQVNNHNIWTIQDAEIIPYKKTTLHLTEKQIRYNRLFTDMLT 128
Query: 167 SKT----FYFSYTFDITNTLQTNILRQKFLSVGRSDIEVPPGIPDYNEMFMWNSYLLDPI 222
FY+S T DI+ T Q L RS ++ +E F+WN +LL I
Sbjct: 129 HVLSIGGFYYSTTLDISRTFQWLQENAVPLFKTRSMLDRA------SERFIWNGHLLSQI 182
Query: 223 FSCIDTVYDWFQPIIHGFIDQVNVSLFGKSIYITLIGRRSHYFAGARFLKRGVNNKGYVA 282
+ + P+IHGFI Q V++ GK I +T+I RRS Y AG RF KRGV+ G+ A
Sbjct: 183 RQ-VPGAERYTLPVIHGFIGQNRVNVNGKEIKLTIISRRSIYRAGVRFYKRGVDVDGHAA 241
Query: 283 NEVETEQIVADMSLTSFHSPARGFFDSDKY-TSFVQHRGSIPLFWSQEASNLTAKPPISI 341
N VETEQIV + + DK+ TSFVQ RGSIPL W+Q+ NL +P ++
Sbjct: 242 NFVETEQIVE-------------YTNPDKHLTSFVQLRGSIPLLWTQK-PNLRWQPMPTL 287
Query: 342 NITDPFYSAAAKHFDKLFQRYGGGTIQILNLIKTKEKNPRETKLGEEFERCIKYLNQFLP 401
TD +A + F Q YGG + I+NL+ K RE K+G E ER + N
Sbjct: 288 KPTDDQLAAFNRAFSWHKQHYGGKHV-IVNLVNQK---GREKKVGGELERISRQAN---- 339
Query: 402 DIKKLEYKAWDMSKASKSHGQMVIEFLEKYAKETVETTGIFHNGKDFQSTS-VQEGVCRT 460
I+ + Y +D K S I+ L + + + + G F+ + TS Q G RT
Sbjct: 340 -IEFVRYHQFDFHKECHSMQWHRIDLLREQLSQEISSFGYFYLSPNSMETSRFQRGFFRT 398
Query: 461 NCIDCLDRTNAAQFVIGKRALGEQLHAMGIIEEKFLEYDSDIV-NILTELFHDHGDTIAL 519
NC+DCLDRTN Q ++ + +L EQL +GI+ + D ++ + +++ D+GD +
Sbjct: 399 NCMDCLDRTNVVQSMLARESLTEQLRMLGILYSEQKVQDIPLLEDAFKQMWADNGDECSR 458
Query: 520 QYGGSHLVNTMETYRKINQWSSHSRDMVESIKRFYSNSFVDAQRQEAINLFLGHY-IWSK 578
QY G+ + T + +D V ++ R+ N+F D RQ++I+LFLG++ + S
Sbjct: 459 QYAGTGALKADFTRHGRRTYVGAMKDGVNAVSRYVRNNFGDGYRQDSIDLFLGNFLVDSS 518
Query: 579 DQPMLWDMS 587
D P+ + S
Sbjct: 519 DLPVSLESS 527
>7292047 [I] KOG1889 Putative phosphoinositide phosphatase
Length = 592
Score = 200 bits (509), Expect = 7e-51
Identities = 150/473 (31%), Positives = 245/473 (51%), Gaps = 41/473 (8%)
Query: 107 IRFTACYYLVVITEMSQVAVLGGHSIYHIDDTELVPITKSTKKRDSTELRFIQSFQNLKL 166
I +C YL+V T V VL G ++ + +++P ++ +R E +++ +
Sbjct: 68 IHLLSCDYLLVATHRLFVGVLNGAVVWRLAGYDIIPYIPNSFQRKENE-NYLRLLRQTLD 126
Query: 167 SKTFYFSYTFDITNTLQTNILRQKFLSVGRSDIEVPPGIPDYNEMFMWNSYLLDPIFSCI 226
+K FYFSY +D+TN+LQ RQ+ V +S EV + + F+WN Y+L F+C
Sbjct: 127 TKFFYFSYRYDLTNSLQ----RQR--EVAQSRPEVSGLLQRAEQRFVWNGYVLRQ-FNC- 178
Query: 227 DTVYDWFQPIIHGFIDQVNVSLFGKSIYITLIGRRSHYFAGARFLKRGVNNKGYVANEVE 286
D + + P++ GF+ V + G++ + ++I RRS AG R RG + +G+VAN VE
Sbjct: 179 DKMEKFQLPLVLGFVSINQVQINGQTFFWSIITRRSVQRAGTRLFCRGSDEQGHVANFVE 238
Query: 287 TEQIVADMSLTSFHSPARGFFDSDKYTSFVQHRGSIPLFWSQEASNLTAKP-PISINITD 345
TEQIV + + T FVQ RGS+P W Q NL KP P+ + D
Sbjct: 239 TEQIVEF---------------NGQLTGFVQTRGSMPFHWHQ-LPNLRYKPRPVLVPGKD 282
Query: 346 PFYSAAAKHFDKLFQRYGGGTIQILNLIKTKEKNPRETKLGEEFERCIKYLNQFLPDIKK 405
+A HF + + YG +NL+ K E +L + R ++ + +
Sbjct: 283 HL-AACGLHFKEQIRLYGNNVA--VNLVDHKGA---EGELEATYARLVREMGN-----PQ 331
Query: 406 LEYKAWDM-SKASKSHGQMVIEFLEKYAKETVETTGIFHNGKDFQSTSVQEGVCRTNCID 464
+ Y+++D S+ K + +++ A E + G++H D + S Q GV RTNCID
Sbjct: 332 VRYESFDFHSECRKMRWDRLNILIDRLAHEQ-DQFGVYHVFDDGKLVSTQTGVFRTNCID 390
Query: 465 CLDRTNAAQFVIGKRALGEQLHAMGIIE-EKFLEYDSDIV-NILTELFHDHGDTIALQYG 522
CLDRTN Q ++ +R+L L +G++ + +E+ SDI +I ++ D+ D ++LQY
Sbjct: 391 CLDRTNVVQSMLARRSLTAVLQKLGVLHVGQKVEHASDIFESIFKGVWADNADLVSLQYS 450
Query: 523 GSHLVNTMETYRKINQWSSHSRDMVESIKRFYSNSFVDAQRQEAINLFLGHYI 575
G+ + T T S +D S+ R+Y N+F D QRQ++I+LFLG Y+
Sbjct: 451 GTCALKTDFTRTGKRTKSGAMQDGKNSLMRYYLNNFADGQRQDSIDLFLGKYL 503
>SPBC19F5.03 [I] KOG1889 Putative phosphoinositide phosphatase
Length = 598
Score = 193 bits (491), Expect = 8e-49
Identities = 153/469 (32%), Positives = 218/469 (45%), Gaps = 44/469 (9%)
Query: 114 YLVVITEMSQVAVLGGHSIYHIDDTELVPITKSTKKRDSTELRFIQSFQNLKLSKTFYFS 173
YL++ TE S A + GH IY + E++P ++ D EL QN + FYFS
Sbjct: 60 YLILATEKSSAAQILGHKIYRVHKFEVIPY-RNLLADDQDELDLYNLLQNHLKTGPFYFS 118
Query: 174 YTFDITNTLQTNILRQ-KFLSVGRSDIEVPPGIPDYNEMFMWNSYLLDPIFSCIDT---V 229
YT+D+TN+LQ + + K + RSD + F WN + I V
Sbjct: 119 YTWDLTNSLQRSCTDEGKASPILRSD-----------KRFFWNEFASKDFIDLIGAHSEV 167
Query: 230 YDWFQPIIHGFIDQVNVSLFGKSIYITLIGRRSHYFAGARFLKRGVNNKGYVANEVETEQ 289
+ P+I+GFI + + G++I + LI RRS AG R+ RG++ G AN ETEQ
Sbjct: 168 SLFITPMIYGFITSASTIVKGRTITLALISRRSKQRAGTRYFTRGLDENGNPANFNETEQ 227
Query: 290 --IVADMSLTSFHSPARGFFDSDKYTSFVQHRGSIPLFWSQEASNLTAKPPISINITDPF 347
IV+D S+ S VQ RGS+P FW+ E +NL KP + N
Sbjct: 228 ITIVSDEK-------------SEVTYSHVQTRGSVPAFWA-EVNNLRYKPLMVANSASMA 273
Query: 348 YSAAAKHFDKLFQRYGGGTIQILNLIKTKEKNPRETKLGEEFERCIKYLNQFLPDIKKLE 407
+AA KHFD+ YG ++NL+ K E + + +E I+ L D +
Sbjct: 274 AAAAKKHFDEQISIYGDQV--VVNLVNCK---GHELPIKQLYENVIRRL-----DNPHIH 323
Query: 408 YKAWDMSK-ASKSHGQMVIEFLEKYAKETVETTGIFHNGKDFQSTSVQEGVCRTNCIDCL 466
Y +D K S V L + E E + + ++ S Q GV R+NC+DCL
Sbjct: 324 YHYFDFHKECSHMRWDRVSLLLNEIQPELEEQGYTTLDTQKYRVLSRQNGVVRSNCMDCL 383
Query: 467 DRTNAAQFVIGKRALGEQLHAMGIIEEKF-LEYDSDIVNILTELFHDHGDTIALQYGGSH 525
DRTN Q IG+ L QL GII L + NI ++ D+ D I+L Y G+
Sbjct: 384 DRTNVVQSCIGRWVLTNQLRKCGIIGATHPLRSVIPLDNIFCNIWSDNADYISLSYSGTG 443
Query: 526 LVNTMETYRKINQWSSHSRDMVESIKRFYSNSFVDAQRQEAINLFLGHY 574
+ T T I D V S KR+ N+F D RQ+A +L LG +
Sbjct: 444 ALKTDFTRTGIRTRKGAFNDFVNSAKRYILNNFYDGARQDAYDLVLGQF 492
>Hs7662338 [I] KOG1889 Putative phosphoinositide phosphatase
Length = 587
Score = 185 bits (470), Expect = 2e-46
Identities = 147/473 (31%), Positives = 223/473 (47%), Gaps = 39/473 (8%)
Query: 107 IRFTACYYLVVITEMSQVAVLGGHSIYHIDDTELVPITKSTKKRDSTELR----FIQSFQ 162
I A YL+VIT+ +V H ++ D +++ K+ +L+ F+
Sbjct: 64 IHLVAGNYLIVITKKIKVGEFFSHVVWKATDFDVLSYKKTMLHLTDIQLQDNKTFLAMLN 123
Query: 163 NLKLSKTFYFSYTFDITNTLQTNILRQKFLSVGRSDIEVPPGIPDYNEMFMWNSYLLDPI 222
++ FYFS T+D+T+TLQ LS + + + ++ F+WN +LL +
Sbjct: 124 HVLNVDGFYFSTTYDLTHTLQR-------LSNTSPEFQEMSLLERADQRFVWNGHLLREL 176
Query: 223 FSCIDTVYDWFQPIIHGFIDQVNVSLFGKSIYITLIGRRSHYFAGARFLKRGVNNKGYVA 282
S V+ + P++HGFI + S+ GK LI RRS + AG R+ RG++++G+ A
Sbjct: 177 -SAQPEVHRFALPVLHGFITMHSCSINGKYFDWILISRRSCFRAGVRYYVRGIDSEGHAA 235
Query: 283 NEVETEQIVADMSLTSFHSPARGFFDSDKYTSFVQHRGSIPLFWSQEASNLTAKPPISIN 342
N VETEQIV ++ K SFVQ RGSIP+FWSQ NL KP I+
Sbjct: 236 NFVETEQIV--------------HYNGSK-ASFVQTRGSIPVFWSQR-PNLKYKPLPQIS 279
Query: 343 ITDPFYSAAAKHFDKLFQRYGGGTIQILNLIKTKEKNPRETKLGEEFERCIKYLNQFLPD 402
+HFD YG I+NLI K E L + F + L +
Sbjct: 280 KVANHMDGFQRHFDSQVIIYGKQV--IINLINQKGS---EKPLEQTFATMVSSLGSGM-- 332
Query: 403 IKKLEYKAWDMSKASKSHGQMVIEFLEKYAKETVETTGIFHNGKDFQSTSVQEGVCRTNC 462
+ Y A+D K K+ + L E + F Q + QEGV R+NC
Sbjct: 333 ---MRYIAFDFHKECKNMRWDRLSILLDQVAEMQDELSYFLVDSAGQVVANQEGVFRSNC 389
Query: 463 IDCLDRTNAAQFVIGKRALGEQLHAMGIIE-EKFLEYDSDIVNILTELFHDHGDTIALQY 521
+DCLDRTN Q ++ +R+L QL +G++ + LE + I + D+ + A QY
Sbjct: 390 MDCLDRTNVIQSLLARRSLQAQLQRLGVLHVGQKLEEQDEFEKIYKNAWADNANACAKQY 449
Query: 522 GGSHLVNTMETYRKINQWSSHSRDMVESIKRFYSNSFVDAQRQEAINLFLGHY 574
G+ + T T D S+ R+Y N+F D RQ++I+LFLG+Y
Sbjct: 450 AGTGALKTDFTRTGKRTHLGLIMDGWNSMIRYYKNNFSDGFRQDSIDLFLGNY 502
>YKL212w [I] KOG1889 Putative phosphoinositide phosphatase
Length = 623
Score = 180 bits (457), Expect = 7e-45
Identities = 139/474 (29%), Positives = 223/474 (46%), Gaps = 50/474 (10%)
Query: 114 YLVVITEMSQVAVLGGHSIYHIDDTELVPITKSTKKRDSTELRFIQSFQNLKLSKTFYFS 173
Y ++ + + GH Y + +V TK + DS E +I+ + + TFYFS
Sbjct: 69 YAIIANTVEETGRFNGHVFYRVLQHSIVS-TKFNSRIDSEEAEYIKLLELHLKNSTFYFS 127
Query: 174 YTFDITNTLQTNILRQKFLSVGRSDIEVPPGIPDYNEMFMWNSYLLDPI--FSCIDTVYD 231
YT+D+TN+LQ N S +D E F WN YL + + F+ D D
Sbjct: 128 YTYDLTNSLQRNEKVGPAASWKTAD-----------ERFFWNHYLTEDLRNFAHQDPRID 176
Query: 232 WF-QPIIHGFIDQVNVSLFGKSIYITLIGRRSHYFAGARFLKRGVNNKGYVANEVETEQI 290
F QP+I+G+ V+ L I + LI RRS + AG R+ +RGV+ G V N ETEQI
Sbjct: 177 SFIQPVIYGYAKTVDAVLNATPIVLGLITRRSIFRAGTRYFRRGVDKDGNVGNFNETEQI 236
Query: 291 VADMSLTSFHSPARGFFDSDKYTSFVQHRGSIPLFWSQEASNLTAKPPISINITDPFYSA 350
+ + S + SF+Q RGS+P++W+ E +NL KP ++ + + A
Sbjct: 237 LLAENPES---------EKIHVFSFLQTRGSVPIYWA-EINNLKYKP--NLVLGENSLDA 284
Query: 351 AAKHFDKLFQRYGGGTIQILNLIKTKEKNPRETKLGEEFERCIKYLNQFLPDIKKLEYKA 410
KHFD+ + YG ++NL+ K E + E +E + LN K+ Y
Sbjct: 285 TKKHFDQQKELYGDN--YLVNLVNQK---GHELPVKEGYESVVHALND-----PKIHYVY 334
Query: 411 WDM----SKASKSHGQMVIEFLEKYAKETVETTGIFH-----NGKDFQSTSVQEGVCRTN 461
+D K +++I+ LEK + FH NG + + Q V RTN
Sbjct: 335 FDFHHECRKMQWHRVKLLIDHLEKLG---LSNEDFFHKVIDSNGNTVEIVNEQHSVVRTN 391
Query: 462 CIDCLDRTNAAQFVIGKRALGEQLHAMGIIEE-KFLEYDSDIVNILTELFHDHGDTIALQ 520
C+DCLDRTN Q V+ + L ++ + ++ E ++ ++ L+ D+ D +++
Sbjct: 392 CMDCLDRTNVVQSVLAQWVLQKEFESADVVATGSTWEDNAPLLTSYQNLWADNADAVSVA 451
Query: 521 YGGSHLVNTMETYRKINQWSSHSRDMVESIKRFYSNSFVDAQRQEAINLFLGHY 574
Y G+ + T T D + S R+Y N++ D RQ++ +LFLG +
Sbjct: 452 YSGTGALKTDFTRTGKRTRLGAFNDFLNSASRYYQNNWTDGPRQDSYDLFLGGF 505
>YNL106c [U] KOG0566 Inositol-145-triphosphate 5-phosphatase (synaptojanin)
INP51/INP52/INP53 family
Length = 1183
Score = 164 bits (416), Expect = 4e-40
Identities = 119/417 (28%), Positives = 203/417 (48%), Gaps = 48/417 (11%)
Query: 169 TFYFSYTFDITNTLQTNILRQKFLSVGRSDIEVPPGIPDYNEMFMWNSYLLDPIFSCIDT 228
+FY+S FD+T TLQ + LS D++ FMWNS+L+D I + D
Sbjct: 175 SFYYSTDFDLTCTLQKRGFTEHSLS-----------FDDFDREFMWNSFLMDEIITYRDR 223
Query: 229 V----------YDWFQPIIHGFIDQVNVSLFGKSIYITLIGRRSHYFAGARFLKRGVNNK 278
+ + +I GF + + + + +T+I R+S AG RF RG+++
Sbjct: 224 LDVTAKELLDQRGFLTTVIRGFAETIFSYINRLKVGLTIISRQSWKRAGTRFNARGIDDD 283
Query: 279 GYVANEVETEQIVADMSLTSFHSPARGFFDSDKYTSFVQHRGSIPLFWSQEASNLTAKPP 338
G+VAN VETE I+ + S +F Q RGS+P+FW Q+ S ++ K
Sbjct: 284 GHVANFVETEMIM---------------YSSQYCYAFTQIRGSLPIFWEQDTSLISPKIQ 328
Query: 339 I--SINITDPFYSAAAKHFDKLFQRYGGGTIQILNLIKTKEKNPRETKLGEEFERCIKYL 396
I S+ T P + +HF +LF++YG + I+NL+ TK E +L ++ +K
Sbjct: 329 ITRSVEATQPTFD---EHFIRLFKKYG--PVHIINLLSTKSS---EIQLSRRYKEQLKN- 379
Query: 397 NQFLPDIKKLEYKAWDMSKASKSHGQMVIEFLEKYAKETVETTGIF-HNGKDFQSTSVQE 455
++ + + + ++D + + G + + T+ G F ++ K+ + S Q+
Sbjct: 380 SEKMKIGRDVFLTSFDFHRETSQDGFAAASRIIPKIRNTILDAGYFSYDVKEGRLISEQD 439
Query: 456 GVCRTNCIDCLDRTNAAQFVIGKRALGEQLHAMGIIEEKFLEYDSDIVNILTELFHDHGD 515
GV RTNC+DCLDRTN Q I L +++ D++ V + L+ D+GD
Sbjct: 440 GVFRTNCLDCLDRTNLIQQTISLAVFKLFLEDFRLVKPSSFIDDNEFVQKVNALWADNGD 499
Query: 516 TIALQYGGSHLVNTMETYRKINQWSSHSRDMVESIKRFYSNSFVDAQRQEAINLFLG 572
I+ Y G++ + + + + +S D +S+ R Y N+FVD +Q+ I+ LG
Sbjct: 500 QISQIYTGTNALKSSYSRKGKMSFSGALSDATKSVSRMYINNFVDKGKQQNIDTLLG 556
>YOR109w [U] KOG0566 Inositol-145-triphosphate 5-phosphatase (synaptojanin)
INP51/INP52/INP53 family
Length = 1107
Score = 163 bits (413), Expect = 9e-40
Identities = 133/473 (28%), Positives = 219/473 (46%), Gaps = 49/473 (10%)
Query: 140 LVPITKSTKKRDSTELRFIQSFQNLKLSKTFYFSYTFDITNTLQTNILRQKFLSVGRSDI 199
++P T ST+ +D+ + L + +FY+S FD+T+TLQ Q LS
Sbjct: 121 VLPETASTEYQDALPKHPCYELKKLLSNGSFYYSSDFDLTSTLQHRGYGQHSLSTDT--- 177
Query: 200 EVPPGIPDYNEMFMWNSYLLDPIFSCIDTV----------YDWFQPIIHGFIDQVNVSLF 249
Y E +MWNS+L+ + + D + + +I GF + +
Sbjct: 178 --------YEEEYMWNSFLMQEMITYRDHLDTNLKQILDDEGFLTTVIRGFAETFVSYVK 229
Query: 250 GKSIYITLIGRRSHYFAGARFLKRGVNNKGYVANEVETEQIVADMSLTSFHSPARGFFDS 309
+ +T+I ++S AG RF RGV+++ VAN VETE I+ + S
Sbjct: 230 KLKVALTIISKQSWKRAGTRFNARGVDDEANVANFVETEFIM---------------YSS 274
Query: 310 DKYTSFVQHRGSIPLFWSQEASNLTAKPPI--SINITDPFYSAAAKHFDKLFQRYGGGTI 367
+F Q RGSIP+FW Q S + + I S T P + KH K ++YG +
Sbjct: 275 QYCYAFTQIRGSIPVFWEQGTSLINPRVQITRSFEATQPVFD---KHIMKSVEKYG--PV 329
Query: 368 QILNLIKTKEKNPRETKLGEEFERCIKYLNQFLPDIKKLEYKAWDMSKASKSHGQMVIEF 427
++NL+ TK +K +E K LN F DI E+ D K + G +
Sbjct: 330 HVVNLLSTKSSEIELSKRYKEHLTHSKKLN-FNKDIFLTEF---DFHKETSQEGFSGVRK 385
Query: 428 LEKYAKETVETTGIF-HNGKDFQSTSVQEGVCRTNCIDCLDRTNAAQFVIGKRALGEQLH 486
L +++ ++G + ++ ++ ++ S Q G+ RTNC+DCLDRTN AQ +I A L
Sbjct: 386 LIPLILDSLLSSGYYSYDVREKKNISEQHGIFRTNCLDCLDRTNLAQQIISLAAFRTFLE 445
Query: 487 AMGIIEEKFLEYDSDIVNILTELFHDHGDTIALQYGGSHLVNTMETYRKINQWSSHSRDM 546
+I D D V+ L+ DHGD I+ Y G++ + + + + + D
Sbjct: 446 DFRLISSNSFIDDDDFVSKHNTLWADHGDQISQIYTGTNALKSSFSRKGKMSLAGALSDA 505
Query: 547 VESIKRFYSNSFVDAQRQEAINLFLGHYIWSKDQPMLWDMSTDFYLHNLYEIS 599
+S+ R Y N+F+D ++Q+ I+ LG + K L+D ++ L +S
Sbjct: 506 TKSVSRIYINNFMDKEKQQNIDTLLGRLPYQK-AVQLYDPVNEYVSTKLQSMS 557
>At5g66020 [I] KOG1889 Putative phosphoinositide phosphatase
Length = 549
Score = 162 bits (409), Expect = 3e-39
Identities = 140/484 (28%), Positives = 213/484 (43%), Gaps = 59/484 (12%)
Query: 106 VIRFTACYYLVVITEMSQVAVLGGHSIYHIDDTELVPITKSTKKRDSTELRFIQSFQNLK 165
+++ A YLVV+TE V GH IY I+ + +P S + + + +
Sbjct: 68 MLKLLAGSYLVVVTESESVGSFLGHPIYKINSLKFLPCDHSLENPHEEQKKMETDDYSRL 127
Query: 166 LSKT-----FYFSYTFDITNTLQTNILRQKFLSVGRSDIEVPPGIPDYNEMFMWNSYLLD 220
LS YFSY ++T T Q + +G + ++ P F+WN+Y+L+
Sbjct: 128 LSVAERTTGLYFSYEINLTLTAQ------RLHDLG-DESKLLPLWRQAEPRFLWNNYMLE 180
Query: 221 PIFSCIDTVYDWFQ-PIIHGFIDQVNVSLFGKSIYITLIGRRSHYFAGARFLKRGVNNKG 279
+ ID D F P+I G I + ITLI RR G R +RG + G
Sbjct: 181 VL---IDNKLDQFLLPVIQGNI-----------VDITLIARRCSRRNGTRMWRRGADPDG 226
Query: 280 YVANEVETEQIVADMSLTSFHSPARGFFDSDKYTSFVQHRGSIPLFWSQEASNLTAKPPI 339
YVAN VETEQIV TS SFVQ RGS+P W Q +LT KP
Sbjct: 227 YVANFVETEQIVRMNGYTS---------------SFVQIRGSMPFMWEQIV-DLTYKPKF 270
Query: 340 SINITDPFYSAAAKHFDKLFQRYGGGTIQILNLIKTKEKNPRETKLGEEFERCIKYLNQF 399
I + A +HF L ++YG + + + E +L E F +++
Sbjct: 271 EIVQPEEAVRIAERHFLDLRKKYGS--------VLAVDLHGGEGRLSERFAGAMQH---- 318
Query: 400 LPDIKKLEYKAWDMSKASKSHGQMVIEFLEKYAKETVETTGIFHNGKDFQSTSVQEGVCR 459
I Y +D + L + ++ +E G F + + Q G+ R
Sbjct: 319 ---ITASRYLHFDFHHICGHIHFERLAILYEQMEDFLEKNGYFLLNEKGEKMKEQLGIVR 375
Query: 460 TNCIDCLDRTNAAQFVIGKRALGEQLHAMGII-EEKFLEYDSDIVNILTELFHDHGDTIA 518
TNCIDCLDRTN Q +IG++ L QL +G+ E+ + + L+ +HGD I+
Sbjct: 376 TNCIDCLDRTNVTQSMIGRKLLELQLKRIGVFGAEETIRSHQNFDECYKILWANHGDDIS 435
Query: 519 LQYGGSHLVNTMETYRKINQWSSHSRDMVESIKRFYSNSFVDAQRQEAINLFLGHYIWSK 578
+QY G+ + +D ++ R+Y N+F D +Q+AI+L GHYI +
Sbjct: 436 IQYSGTPALKGDFVRYGQRTIQGVLQDGWNALARYYLNNFADGTKQDAIDLVQGHYIVAV 495
Query: 579 DQPM 582
+ M
Sbjct: 496 SRDM 499
>SPBC2G2.02 [U] KOG0566 Inositol-145-triphosphate 5-phosphatase (synaptojanin)
INP51/INP52/INP53 family
Length = 1076
Score = 152 bits (385), Expect = 2e-36
Identities = 132/448 (29%), Positives = 196/448 (43%), Gaps = 57/448 (12%)
Query: 160 SFQNLKLSKTFYFSYTFDITNTLQTNILRQKFLSVGRSDIEVPPGIPDYNEMFMWNSYLL 219
S + L + +FYFS FDIT LQ S P + FMWN ++L
Sbjct: 143 SLRKLLTNGSFYFSLDFDITTRLQLRT----------SQTMTEPQYDSMHTQFMWNEFML 192
Query: 220 DPIF-----------SCIDTVYDWFQPIIHGFIDQVNVSLFGKSIYITLIGRRSHYFAGA 268
+ S +D +F I GF L ++I ++LI R S AG
Sbjct: 193 RQLIKFRSHLNGDEKSALDGCR-FFTCAIRGFASTEQFKLGIQTIRLSLISRLSSLRAGT 251
Query: 269 RFLKRGVNNKGYVANEVETEQIVADMSLTSFHSPARGFFDSDKY-TSFVQHRGSIPLFWS 327
RFL RGV++ G VAN VETE I+ DS KY S+ Q RGSIP+FW
Sbjct: 252 RFLSRGVDDDGNVANFVETETIL----------------DSSKYCVSYCQVRGSIPIFWE 295
Query: 328 QEASNLTAKPPISINITDPFYSAAAKHFDKLFQRYGGGTIQILNLIKTKEKNPRETKLGE 387
QE + + + +A KHF L + YG + I+NL+ T E L E
Sbjct: 296 QEGVQMFGQKIDITRSLEATRAAFEKHFTSLIEEYG--PVHIINLLGT---GSGERSLSE 350
Query: 388 EFERCIKYLNQFLPDIKKLEYKAWDMSKASKSHGQMVIEFLEKYAKETVETTGIFHNGKD 447
+ I Q P+ + +D +S + ET G + +
Sbjct: 351 RLRQHI----QLSPEKDLIHLTEFDYHSQIRSFEDA--NKIRPMIYSDAETFGFYFENNE 404
Query: 448 FQSTSVQEGVCRTNCIDCLDRTNAAQFVIGKRALGEQLHAMGIIEEKFLEYDSDIVNILT 507
QS VQ+GV RTNC+DCLDRTN Q ++ + L + + I + Y D + +
Sbjct: 405 GQSIVVQDGVFRTNCLDCLDRTNVIQNLVSRVFLEQVM----IYTRQNAGY--DFWQVHS 458
Query: 508 ELFHDHGDTIALQYGGSHLVNTMETYRKINQWSSHSRDMVESIKRFYSNSFVDAQRQEAI 567
++ ++GD +A Y G+ + + T + + D+ +S+ R Y N+F D RQE I
Sbjct: 459 TIWANNGDALARIYTGTGALKSSFTRKGKLSIAGALNDLSKSVGRMYINNFQDKGRQETI 518
Query: 568 NLFLGHYIWSKDQPMLWDMSTDFYLHNL 595
+L LG I + +L+D ++ H L
Sbjct: 519 DLLLGRLI-DQHPVILYDPIHEYVNHEL 545
>At3g51830 [I] KOG1889 Putative phosphoinositide phosphatase
Length = 599
Score = 152 bits (384), Expect = 2e-36
Identities = 140/492 (28%), Positives = 221/492 (44%), Gaps = 55/492 (11%)
Query: 107 IRFTACYYLVVITEMSQVAVLGGHSIYHIDDTELVPITKSTK------KRDSTELRFIQS 160
IR A YL+VIT +V G I+ + + +P ++ + K+D T R +
Sbjct: 71 IRLLAGTYLLVITSREEVGNFLGLPIFRVTAMKFLPCNEALRFATAQEKKDETYFRTL-- 128
Query: 161 FQNLKLSKTFYFSYTFDITNTLQTNIL-----RQKFLSVGRSDIEVPPGIPDYNEMFMWN 215
Q L+ + YFSY D+T LQ +K + + P Y +WN
Sbjct: 129 LQALETTPGLYFSYETDLTLNLQRRCKLAEGWNRKPMWKQAEGLFACQADPRY----VWN 184
Query: 216 SYLLDPIFSCIDTVYDWFQPIIHGFIDQV-NVSLFGKSIYITLIGRRSHYFAGARFLKRG 274
+LL+ + C + I G QV + L ++++ RR G R +RG
Sbjct: 185 WHLLEDLIECKTVLQYMLFDINQGLSYQVAELKLKNSPAVVSIMSRRCTRRLGTRMWRRG 244
Query: 275 VNNKGYVANEVETEQIVADMSLTSFHSPARGFFDSDKYTSFVQHRGSIPLFWSQEASNLT 334
N +G AN VE+EQIV GF K+ S +Q RGSIPL W Q +L+
Sbjct: 245 ANLEGDAANFVESEQIVE----------INGF----KF-SLLQVRGSIPLLWEQIV-DLS 288
Query: 335 AKPPISINITDPFYSAAAKHFDKLFQRYGGGTIQILNLIKTKEKNPRETKLGEEFERCIK 394
KP + IN + +HF L QRYG +I+ + T + G+E
Sbjct: 289 YKPRLKINKHEETPKVVQRHFHDLCQRYG----EIMAVDLTDQH-------GDEGALSKA 337
Query: 395 YLNQF--LPDIKKLEYKAWDMSKASKSHGQMVIEFLEKYAKETVETTGIFHNGKDFQSTS 452
Y + LPD++ Y ++D + + + L + + E G F D
Sbjct: 338 YATEMEKLPDVR---YVSFDFHQVCGTTNFDNLGVLYEQIGDEFEKQGYFLVDADENILE 394
Query: 453 VQEGVCRTNCIDCLDRTNAAQFVIGKRALGEQLHAMGIIE--EKFLEYDSDIVNILTELF 510
Q+GV R+NCIDCLDRTN Q +G+++L QL +G+ + E ++ D T ++
Sbjct: 395 EQKGVIRSNCIDCLDRTNVTQSFMGQKSLNLQLQRIGVCDSTECISTFEDDYTKFRT-IW 453
Query: 511 HDHGDTIALQYGGSH-LVNTMETYRKINQWSSHSRDMVESIKRFYSNSFVDAQRQEAINL 569
+ GD ++LQY G++ L + Y K + +D + ++ R+Y N+F D RQ+A++L
Sbjct: 454 AEQGDEVSLQYAGTYALKGDLVRYGK-QTMTGAIKDGLSAMSRYYLNNFQDGVRQDALDL 512
Query: 570 FLGHYIWSKDQP 581
G Y P
Sbjct: 513 ISGRYTVGTHSP 524
>7300754 [I] KOG1890 Phosphoinositide phosphatase SAC1
Length = 987
Score = 152 bits (384), Expect = 2e-36
Identities = 121/410 (29%), Positives = 184/410 (44%), Gaps = 42/410 (10%)
Query: 169 TFYFSYTFDITNTLQTNILRQKFLSVGRSDIEVPPGIPDYNEMFMWNSYLLDPIFSCIDT 228
+FYFS+ DITN LQ + + E PD E F WN +++ + + D
Sbjct: 204 SFYFSFDCDITNNLQRHEAKS----------EESQSQPD--ERFFWNKHMIRDLINLNDK 251
Query: 229 VYDWFQPIIHGFIDQVNVSLFGKSIYITLIGRRSHYFAGARFLKRGVNNKGYVANEVETE 288
W PII GF+ N + + + L+ RRS + AG R+ +RGV+ KG AN VETE
Sbjct: 252 T--WILPIIQGFMQVENCVIGNECFTLALVSRRSRHRAGTRYKRRGVDEKGNCANYVETE 309
Query: 289 QIVADMSLTSFHSPARGFFDSDKYTSFVQHRGSIPLFWSQEASNLTAKPPISINITDPFY 348
QI+ SF SF Q RGS+P++WSQ P + + +
Sbjct: 310 QIL------SFR---------HHQLSFTQVRGSVPIYWSQPGYKYRPPPRLDRGVAET-Q 353
Query: 349 SAAAKHFDKLFQRYGGGTIQILNLIKTKEKNPRETKLGEEFERCIKYLNQFLPDIKKLEY 408
A HF K + Y G + I+NL+ E++ +E +G+ + + LN +L Y
Sbjct: 354 QAFELHFTKELETY--GRVCIVNLV---EQSGKEKTIGDAYADHVIKLNN-----DRLIY 403
Query: 409 KAWDMSKASKSHGQMVIEFLEKYAKETVETTGIFHNGKDFQSTSVQEGVCRTNCIDCLDR 468
+D + + L G FH Q+ V R NC+DCLDR
Sbjct: 404 VTFDFHDYCRGMRFENVSALIDAVGPEAGAMG-FHWRDQRGMICNQKSVFRVNCMDCLDR 462
Query: 469 TNAAQFVIGKRALGEQLHAMGIIEEKFLEYDSDIVNILTELFHDHGDTIALQYGGSHLVN 528
TN Q IGK L QL +G + + + + L+ ++GD I+ QY G++ +
Sbjct: 463 TNVVQTAIGKAVLESQLVKLG-LSPPYTPIPEQLKSPFMVLWANNGDIISRQYAGTNALK 521
Query: 529 TMETYRKINQWSSHSRDMVESIKRFYSNSFVDAQRQEAINLFLGHYIWSK 578
T + S +D + S R+Y F D+ RQ I+L LG+ + S+
Sbjct: 522 GDYTRTGERKISGMMKDGMNSANRYYLARFKDSYRQATIDLMLGNQVSSE 571
>CE20170 [I] KOG1890 Phosphoinositide phosphatase SAC1
Length = 783
Score = 142 bits (357), Expect = 3e-33
Identities = 123/417 (29%), Positives = 188/417 (44%), Gaps = 60/417 (14%)
Query: 167 SKTFYFSYTFDITNTLQTNILRQKFLSVGRSDIEVPPGIPDYNEMFMWNSYLLDPIFSCI 226
SK FYF + D+T I QK+ + + F WN ++ +
Sbjct: 152 SKDFYFCRSRDVT------ISSQKYFEKREAHTS--------EDSFFWNKRMVGNLGEA- 196
Query: 227 DTVYDWFQ-PIIHGFI--------DQVNVSLFGKSIYITLIGRRSHYFAGARFLKRGVNN 277
+ D F PI+ G++ DQ+N L IT+I RRS AGAR+L+RG++
Sbjct: 197 -KISDKFTCPIMQGYVATSQLEITDQINAYLT-----ITIISRRSTRRAGARYLRRGIDE 250
Query: 278 KGYVANEVETEQIVADMSLTSFHSPARGFFDSDKYTSFVQHRGSIPLFWSQEASNLTAKP 337
VAN VETE I+ F+ + SFVQ RGSIP+FWSQ +P
Sbjct: 251 ASNVANFVETELIL-------------NIFEHE--LSFVQCRGSIPVFWSQRGFKY--RP 293
Query: 338 PISINIT-DPFYSAAAKHFDKLFQRYGGGTIQILNLIKTKEKNPRETKLGEEF-ERCIKY 395
P+ IN + + + +HF +L Y + + ++ RE L + F E C+K
Sbjct: 294 PLIINRSVEETHGVFTEHFKRLKAHYDTPLVAV----SLVDQRGRELPLAQRFLEHCVK- 348
Query: 396 LNQFLPDIKKLEYKAWDMSKASKSHGQMVIEFLEKYAKETVETTGIFHNGKDFQSTSVQE 455
D + + ++D+ + + ++ L +ET++T G K + Q+
Sbjct: 349 -----ADDNDVTFFSFDLHQHCRGLNFQKLQTLISSMEETLKTIGFCWVDKTGEVVQSQK 403
Query: 456 GVCRTNCIDCLDRTNAAQFVIGKRALGEQLHAMGIIEEKFLEYDSDIVNILTELFHDHGD 515
GV RTNCIDCLDRTN Q I + +Q +GI E +V + ++ D+GD
Sbjct: 404 GVVRTNCIDCLDRTNLVQGQISLFVVLQQAQRLGIF-GPLCEPPEVLVQTMQTMWADNGD 462
Query: 516 TIALQYGGSHLVNTMETYRKINQWSSHSRDMVESIKRFYSNSFVDAQRQEAINLFLG 572
I+ QY G+ + T + +D S R+Y DAQRQ+AIN+ G
Sbjct: 463 VISTQYAGTAALKGDVTRNGERKLMGVMKDGYNSASRYYLTHTKDAQRQKAINIVTG 519
>At3g51460 [I] KOG1889 Putative phosphoinositide phosphatase
Length = 603
Score = 140 bits (352), Expect = 1e-32
Identities = 148/562 (26%), Positives = 242/562 (42%), Gaps = 106/562 (18%)
Query: 80 MEVLRKIEEADDDAXXXXXXXXXXXXVIRFTACYYLVVITEMSQVAVLGGHSIYHIDDTE 139
M+++ ++ E++ +++ A YLVV+TE +V GH I+ + +
Sbjct: 45 MKLIDQVPESNSVRVPKIRSIFGVVGMLKLLAGSYLVVVTESERVGSFLGHPIFKVTTLK 104
Query: 140 LVPITKSTKKRDSTELRFIQSFQNL----KLSKTFYFSYTFDITNTLQTNILRQKFLSVG 195
++P S K + + F L + + YFSY ++T + Q+ +G
Sbjct: 105 VLPCDHSLKNSPEEQKKMETEFSKLLSVAEKTTGLYFSYEVNLT------LSSQRLHEMG 158
Query: 196 RSDIEVPPGIPDYNEMFMWNSYLLDPIFSCIDTVYDWFQ-PIIHGFI--DQVNVSLFGKS 252
+P F+WN+Y+L+ + ID D F P+I G I Q + G+
Sbjct: 159 DESKSLPLW-RQAEPRFLWNNYMLEVL---IDNKLDQFLLPVIQGNILCYQFFETAIGRD 214
Query: 253 IY-ITLIGRR-----SHYFA-------------------------GARFLKRGVNNKGYV 281
I ITLI RR Y + G R +RG + GYV
Sbjct: 215 IVDITLIARRCTRRNERYMSLPAGNLNAEYCVVNVSSPLSWIVLQGTRMWRRGADLDGYV 274
Query: 282 ANEVETEQIVADMSLTSFHSPARGFFDSDKYTSFVQHRGSIPLFWSQEASNLTAKPPISI 341
AN VETEQIV TS SFVQ RGS+P W Q +LT KP I
Sbjct: 275 ANFVETEQIVQMNGYTS---------------SFVQVRGSMPFMWEQVV-DLTYKPKFEI 318
Query: 342 NITDPFYSAAAKHFDKLFQRYGGGTIQILNLIKTKEKNPRETKLGEEFERCIKYLNQFLP 401
+ A +HF L ++YG ++ ++L+ K E +L E++ ++++
Sbjct: 319 VQPEEAKRIAERHFLDLRKKYG--SVLAVDLVN---KQGGEGRLCEKYATVMQHITG--D 371
Query: 402 DIKKLEYKAWDMSKASKSHGQMVIEFLEKYAKETVETTGIFHNGKDFQSTSVQEGVCRTN 461
DI+ L + + H + + L + + +E G F + + Q GV R+N
Sbjct: 372 DIRYLHFDFHQI--CGHIHFER-LSILYEQIEGFLEKNGYFLLNEKGEKMKEQLGVVRSN 428
Query: 462 CIDCLDRTNAAQFVIGKRALGE-------QLHAMGIIEEKFLEYDSDIVNILTELFHDHG 514
CIDCLDRTN Q V K+ + + +HA + + D+ ++ +HG
Sbjct: 429 CIDCLDRTNVTQ-VSHKKTMMQLISYWPLLIHAAYFLPNAEHDRSKDV-----RIWANHG 482
Query: 515 DTIALQYGGS------------HLVNTMETYRKINQWSSHS--RDMVESIKRFYSNSFVD 560
D I++QY G+ H+ N +R ++H +D S++R+Y N+F D
Sbjct: 483 DEISIQYSGTPALKGDFVRYFCHMFNLGYGHR-----TAHGVLKDGWSSLRRYYLNNFAD 537
Query: 561 AQRQEAINLFLGHYIWSKDQPM 582
+Q+AI+L GHYI + + M
Sbjct: 538 GTKQDAIDLLQGHYIVAVSRDM 559
>Hs4507335 [U] KOG0566 Inositol-145-triphosphate 5-phosphatase (synaptojanin)
INP51/INP52/INP53 family
Length = 1575
Score = 138 bits (348), Expect = 3e-32
Identities = 125/462 (27%), Positives = 207/462 (44%), Gaps = 54/462 (11%)
Query: 110 TACYYLVVITEMSQVAVLGGHSIYHIDDTELVPITKSTKKRDSTELRFIQSFQNLKLSKT 169
T +YLV++T V + ++ + TE + + + DS++ I + + S
Sbjct: 73 TMLHYLVLVTGCMSVGKIQESEVFRVTSTEFISL-----RIDSSDEDRISEVRKVLNSGN 127
Query: 170 FYFSYTFDITNTLQTNILRQKFLSVGRSDIEVPPGIPDYNEMFMWNSYLLDPIFSCIDTV 229
FYF+++ + I L+ RS E + F WN L +
Sbjct: 128 FYFAWS-------ASGISLDLSLNAHRSMQEQTT-----DNRFFWNQSLHLHLKHYGVNC 175
Query: 230 YDWFQPIIHGFIDQVNVSLFGKSIYITLIGRRSHYFAGARFLKRGVNNKGYVANEVETEQ 289
DW ++ G ++ + K LI R S AG RF RG N+ G+VAN VETEQ
Sbjct: 176 DDWLLRLMCGGVEIRTIYAAHKQAKACLISRLSCERAGTRFNVRGTNDDGHVANFVETEQ 235
Query: 290 IVADMSLTSFHSPARGFFDSDKYTSFVQHRGSIPLFWSQEASNLTAKPPISINITDPFYS 349
+V + D +SF+Q RGS+PLFW Q + + +
Sbjct: 236 VV---------------YLDDSVSSFIQIRGSVPLFWEQPGLQVGSHRVRMSRGFEANAP 280
Query: 350 AAAKHFDKLFQRYGGGTIQILNLIKTKEKNPRETKLGEEFERCIKYLNQFLPDIKKLEYK 409
A +HF L YG I +NL+ +KE E L + F+ +K ++ DI+ + +
Sbjct: 281 AFDRHFRTLKNLYGRQII--VNLLGSKEG---EHMLSKAFQSHLK-ASEHAADIQMVNFD 334
Query: 410 AWDMSKASKSHGQMVIEFLEKYAKETVETTGIFHNGKDFQSTSVQEGVCRTNCIDCLDRT 469
M K K+ + + L+ ++ ++ + NG + Q Q G RTNC+DCLDRT
Sbjct: 335 YHQMVKGGKA--EKLHSVLKPQVQKFLDYGFFYFNGSEVQRC--QSGTVRTNCLDCLDRT 390
Query: 470 NAAQFVIGKRALGEQLHAMGIIEEKFLEYDSDIVNILTELFHDHGDTIALQYGGSHLVNT 529
N+ Q +G L +QL A+G+ E+ L + + ++ +GD+I+ Y G+
Sbjct: 391 NSVQAFLGLEMLAKQLEALGLAEKPQLV--TRFQEVFRSMWSVNGDSISKIYAGT---GA 445
Query: 530 METYRKINQWSSHSRDMVESIKRFYSNSFVDAQRQEAINLFL 571
+E K+ +D S+ R N+F D+ +QEAI++ L
Sbjct: 446 LEGKAKL-------KDGARSVTRTIQNNFFDSSKQEAIDVLL 480
>Hs7662414 [I] KOG1890 Phosphoinositide phosphatase SAC1
Length = 1132
Score = 135 bits (340), Expect = 3e-31
Identities = 127/466 (27%), Positives = 207/466 (44%), Gaps = 86/466 (18%)
Query: 145 KSTKKRDSTELRFIQSFQNLKL-SKTFYFSYTFDITNTLQTNILRQKFLSVGRSDIEVPP 203
K +K+++ E R ++ + + S++FY+S T+D+TN++Q S G D P
Sbjct: 150 KESKEKEKLERRLLEELLKMFMDSESFYYSLTYDLTNSVQRQ-------STGERDGR--P 200
Query: 204 GIPDYNEMFMWNSYLLDPIFSCIDTVYD-WFQPIIHGF--IDQVNVSLFGKS-------- 252
++ F WN Y++ + D W P+I GF I+++ V+ S
Sbjct: 201 LWQKVDDRFFWNKYMIQDLTEIGTPDVDFWIIPMIQGFVQIEELVVNYTESSDDEKSSPE 260
Query: 253 ---------------IYITLIGRRSHYFAGARFLKRGVNNKGYVANEVETEQIVADMSLT 297
+ LI RRS + AG R+ +RGV+ G VAN VETEQ++ + T
Sbjct: 261 TPPQESTCVDDIHPRFLVALISRRSRHRAGMRYKRRGVDKNGNVANYVETEQLIHVHNHT 320
Query: 298 SFHSPARGFFDSDKYTSFVQHRGSIPLFWSQEASNLTAKPPI--SINITDPFYSAAAKHF 355
SFVQ RGS+P+FWSQ +P + S T ++ A HF
Sbjct: 321 ---------------LSFVQTRGSVPVFWSQVGYRYNPRPRLDRSEKETVAYFCA---HF 362
Query: 356 DKLFQRYGGGTIQILNLIKTKEKNPRETKLGEEFERCIKYLNQFLPDIKKLEYKAWDMSK 415
++ Y I +NL+ ++ RE +G+ + + + N L Y ++D +
Sbjct: 363 EEQLNIYKKQVI--INLV---DQAGREKIIGDAYLKQVLLFNN-----SHLTYVSFDFHE 412
Query: 416 ASKSHGQMVIEFLEKYAKETVETTGIFHNGKDFQSTSV--------QEGVCRTNCIDCLD 467
+ K+ T I+ D + V QEG+ R NC+DCLD
Sbjct: 413 HCRGM---------KFENVQTLTDAIYDIILDMKWCWVDEAGVICKQEGIFRVNCMDCLD 463
Query: 468 RTNAAQFVIGKRALGEQLHAMGII-EEKFLEYDSDIVNILTELFHDHGDTIALQYGGSHL 526
RTN Q I + + +QL +G++ E+ L + I ++ ++GD+I+ QY G+
Sbjct: 464 RTNVVQAAIARVVMEQQLKKLGVMPPEQPLPVKCN--RIYQIMWANNGDSISRQYAGTAA 521
Query: 527 VNTMETYRKINQWSSHSRDMVESIKRFYSNSFVDAQRQEAINLFLG 572
+ T + + +D V S R+Y N F DA RQ I+L G
Sbjct: 522 LKGDFTRTGERKLAGVMKDGVNSANRYYLNRFKDAYRQAVIDLMQG 567
>7291368 [U] KOG0566 Inositol-145-triphosphate 5-phosphatase (synaptojanin)
INP51/INP52/INP53 family
Length = 1218
Score = 135 bits (339), Expect = 4e-31
Identities = 129/479 (26%), Positives = 201/479 (41%), Gaps = 84/479 (17%)
Query: 114 YLVVITEMSQVAVLGGHSIYHIDDTELVPITKSTKKRDSTELRFIQSFQNLKLSKTFYF- 172
+LV++T + +G I+ I T V + + D I + L S TFYF
Sbjct: 78 FLVLVTGCVSMGKIGDIEIFRITQTTFVSLQNAAPNEDK-----ISEVRKLLNSGTFYFA 132
Query: 173 ------------SYTFDITNTLQTNILRQKFLSVGRSDIEVPPGIPDYNEMFMWNSYLLD 220
SY FDIT Q Q + + F WN +
Sbjct: 133 HTNASASASGASSYRFDITLCAQRRQQTQ-----------------ETDNRFFWNRMMHI 175
Query: 221 PIFSCIDTVYDWFQPIIHGFIDQVNVSLFGKSIYITLIGRRSHYFAGARFLKRGVNNKGY 280
+ W + G ++ V + K +I R S AG RF RG N++GY
Sbjct: 176 HLMRFGIDCQSWLLQAMCGSVEVRTVYIGAKQARAAIISRLSCERAGTRFNVRGTNDEGY 235
Query: 281 VANEVETEQIVADMSLTSFHSPARGFFDSDKYTSFVQHRGSIPLFWSQEASNLTAKPPIS 340
VAN VETEQ++ + D D TS+VQ RGS+PLFW Q + +
Sbjct: 236 VANFVETEQVI--------------YVDGD-VTSYVQTRGSVPLFWEQPGVQVGSH---K 277
Query: 341 INITDPFYSAAA---KHFDKLFQRYGGGTIQIL---NLIKTKEKNPRETKLGEEFERCIK 394
+ ++ F ++AA +H + QRYG T+ L +L+ +KE E L EF+R
Sbjct: 278 VKLSRGFETSAAAFDRHMSMMRQRYGYQTVVNLLGSSLVGSKEG---EAMLSNEFQR--- 331
Query: 395 YLNQFLPDIKKLEYKAWDMSKASKSHGQMVIEFLEKYAKETVETTGIFHNGKDFQSTSVQ 454
+ + K + + +D + + + L++ G+FH + Q Q
Sbjct: 332 --HHGMSAHKDVPHVVFDYHQECRGGNFSALAKLKERIVACGANYGVFH-ASNGQVLREQ 388
Query: 455 EGVCRTNCIDCLDRTNAAQFVIGKRALGEQLHA--MGIIEEKFLEYDSDIVNILTELFHD 512
GV RTNC+DCLDRTN Q +G LG QL A MG ++ ++ I +++ +
Sbjct: 389 FGVVRTNCLDCLDRTNCVQTYLGLDTLGIQLEALKMGGKQQNISRFE----EIFRQMWIN 444
Query: 513 HGDTIALQYGGSHLVNTMETYRKINQWSSHSRDMVESIKRFYSNSFVDAQRQEAINLFL 571
+G+ ++ Y G+ + Q S D S R N+ +D +QEAI++ L
Sbjct: 445 NGNEVSKIYAGTGAI----------QGGSKLMDGARSAARTIQNNLLDNSKQEAIDVLL 493
>CE29050 [U] KOG0566 Inositol-145-triphosphate 5-phosphatase (synaptojanin)
INP51/INP52/INP53 family
Length = 1119
Score = 123 bits (309), Expect = 1e-27
Identities = 127/459 (27%), Positives = 200/459 (42%), Gaps = 59/459 (12%)
Query: 115 LVVITEMSQVAVLGGHSIYHIDDTELVPITKSTKKRDSTELRFIQSFQNLKLSKTFYFS- 173
LV +T + V L G I I + E + + ++ ++ + R I Q L S+ FYFS
Sbjct: 75 LVAVTGVLSVGQLYGADILKITNVEFISL-RTFGSVENVDSRIID-LQRLLSSQMFYFSS 132
Query: 174 -YTFDITNTLQTNILRQKFLSVGRSDIEVPPGIPDYNEMFMWNSYLLDPIFSCIDTVYDW 232
++D+T + Q S SD F WN L +W
Sbjct: 133 LQSYDLTRSAQHRD------SHDCSDAR-----------FFWNRSLHFSFQRYGIDTDNW 175
Query: 233 FQPIIHGFIDQVNVSLFGKSIYITLIGRRSHYFAGARFLKRGVNNKGYVANEVETEQIVA 292
+ G + V + + + LI R S G RF RG N G VAN VETEQ++
Sbjct: 176 LLKCMAGSVLVRVVYVGANTGRVALISRLSCERVGTRFNVRGANYLGNVANFVETEQLL- 234
Query: 293 DMSLTSFHSPARGFFDSDKYTSFVQHRGSIPLFWSQEASNLTAKPPISINITDPFYSAAA 352
FD +K S +Q RGSIPLFW Q N+ + + + + A
Sbjct: 235 -------------LFD-EKECSLLQIRGSIPLFWEQPGVNVGSHK-VKLRAFETSLPAYH 279
Query: 353 KHFDKLFQRYGGGTIQILNLIKTKEKNPRETKLGEEFERCIKYLNQFLPDIKKLEYKAWD 412
+H +L RYG I+NL+ KE E LG+ F+ K + F P + +++
Sbjct: 280 RHLSQLQHRYG--EFAIVNLLGRKEG---ERVLGDAFKTQHKS-SHFAPLVDFIDFDYHA 333
Query: 413 MSKASKSHGQMVIEFLEKYAKETVETTGIFHNGKDFQSTSVQEGVCRTNCIDCLDRTNAA 472
K SK + +++ +K + + + GK+ Q GV RTNC+DCLDRTNA
Sbjct: 334 QMKISK---EAIVQLKKKMSPHMTKHGFFYSMGKEIVKR--QTGVIRTNCLDCLDRTNAV 388
Query: 473 QFVIGKRALGEQLHAMGIIEEKFLEYDSDIVNILTELFHDHGDTIALQYGGSHLVNTMET 532
Q IG + +Q+ + + K + + + IL +L+ +GD + Y G+ ++
Sbjct: 389 QTAIGLQMSHDQVAFLNLNAGK-VNVEQRVEEILRDLWQKNGDQCSTIYAGTGALD---- 443
Query: 533 YRKINQWSSHSRDMVESIKRFYSNSFVDAQRQEAINLFL 571
S +D S+ R N+ +D +QE+ +LFL
Sbjct: 444 ------GKSKLKDASRSLARTIQNNLMDGAKQESFDLFL 476
>CE28239 [U] KOG0566 Inositol-145-triphosphate 5-phosphatase (synaptojanin)
INP51/INP52/INP53 family
Length = 1113
Score = 123 bits (309), Expect = 1e-27
Identities = 127/459 (27%), Positives = 200/459 (42%), Gaps = 59/459 (12%)
Query: 115 LVVITEMSQVAVLGGHSIYHIDDTELVPITKSTKKRDSTELRFIQSFQNLKLSKTFYFS- 173
LV +T + V L G I I + E + + ++ ++ + R I Q L S+ FYFS
Sbjct: 75 LVAVTGVLSVGQLYGADILKITNVEFISL-RTFGSVENVDSRIID-LQRLLSSQMFYFSS 132
Query: 174 -YTFDITNTLQTNILRQKFLSVGRSDIEVPPGIPDYNEMFMWNSYLLDPIFSCIDTVYDW 232
++D+T + Q S SD F WN L +W
Sbjct: 133 LQSYDLTRSAQHRD------SHDCSDAR-----------FFWNRSLHFSFQRYGIDTDNW 175
Query: 233 FQPIIHGFIDQVNVSLFGKSIYITLIGRRSHYFAGARFLKRGVNNKGYVANEVETEQIVA 292
+ G + V + + + LI R S G RF RG N G VAN VETEQ++
Sbjct: 176 LLKCMAGSVLVRVVYVGANTGRVALISRLSCERVGTRFNVRGANYLGNVANFVETEQLL- 234
Query: 293 DMSLTSFHSPARGFFDSDKYTSFVQHRGSIPLFWSQEASNLTAKPPISINITDPFYSAAA 352
FD +K S +Q RGSIPLFW Q N+ + + + + A
Sbjct: 235 -------------LFD-EKECSLLQIRGSIPLFWEQPGVNVGSHK-VKLRAFETSLPAYH 279
Query: 353 KHFDKLFQRYGGGTIQILNLIKTKEKNPRETKLGEEFERCIKYLNQFLPDIKKLEYKAWD 412
+H +L RYG I+NL+ KE E LG+ F+ K + F P + +++
Sbjct: 280 RHLSQLQHRYG--EFAIVNLLGRKEG---ERVLGDAFKTQHKS-SHFAPLVDFIDFDYHA 333
Query: 413 MSKASKSHGQMVIEFLEKYAKETVETTGIFHNGKDFQSTSVQEGVCRTNCIDCLDRTNAA 472
K SK + +++ +K + + + GK+ Q GV RTNC+DCLDRTNA
Sbjct: 334 QMKISK---EAIVQLKKKMSPHMTKHGFFYSMGKEIVKR--QTGVIRTNCLDCLDRTNAV 388
Query: 473 QFVIGKRALGEQLHAMGIIEEKFLEYDSDIVNILTELFHDHGDTIALQYGGSHLVNTMET 532
Q IG + +Q+ + + K + + + IL +L+ +GD + Y G+ ++
Sbjct: 389 QTAIGLQMSHDQVAFLNLNAGK-VNVEQRVEEILRDLWQKNGDQCSTIYAGTGALD---- 443
Query: 533 YRKINQWSSHSRDMVESIKRFYSNSFVDAQRQEAINLFL 571
S +D S+ R N+ +D +QE+ +LFL
Sbjct: 444 ------GKSKLKDASRSLARTIQNNLMDGAKQESFDLFL 476
>ECU03g1160 [I] KOG1889 Putative phosphoinositide phosphatase
Length = 518
Score = 120 bits (300), Expect = 1e-26
Identities = 116/452 (25%), Positives = 196/452 (42%), Gaps = 74/452 (16%)
Query: 106 VIRFTACYYLVVITEMSQVAVLGGHSIYHIDDTELVPITKSTKKRDSTELRFIQSFQNLK 165
+I + YL+++ + ++ H++Y I D E++ +T+ K + E++ ++ F
Sbjct: 49 MITISKSSYLILVVDAVIRGMMYEHAVYEIRDVEIIQLTREKAKNFTNEMKNVKKF---- 104
Query: 166 LSKTFYFSYTFDITNTLQTNILRQKFLSVGRSDIEVPPGIPDYNEMFMWNSYLLDPIFSC 225
L KT + T+ + T+ D ++ F++NS L+
Sbjct: 105 LEKTGIYFSTYPLYKTMSIK--------------------KDEDKDFLFNSLPLEKFLGH 144
Query: 226 IDTVYDWFQP-IIHGFIDQVNVSLFGKSIYITLIGRRSHYFAGARFLKRGVNNKGYVANE 284
F I GF V++ ++ + LI RRS AGAR+ RG + GYV+N
Sbjct: 145 AGDKGSLFSVWCIQGFFGSVDIG----TVCLRLISRRSWRRAGARYFSRGSDASGYVSNY 200
Query: 285 VETEQIVADMSLTSFHSPARGFFDSDKYTSFVQHRGSIPLFWSQEASNLTAKPPISINIT 344
VETEQI+ +D +K S +Q RGSIPL W + P I ++
Sbjct: 201 VETEQII---------------YDGEKTVSHLQVRGSIPLIW-EHVLGREYNPKIVVSDR 244
Query: 345 DPFYSAAAKHFDKLFQRYGGGTIQILNLIKTKEKNPRETKLGEEFERCIKYLNQFLPDIK 404
+ A DK G + LNLI+ G E Y + L + K
Sbjct: 245 KILHIADKVLRDKY------GDVFYLNLIRNS---------GYEGMLHCAYEKELLGNNK 289
Query: 405 KLEYKAWDMSKASKSHGQMVIEFLEKYAKETVETTGIFHNGKDFQSTSVQEGVCRTNCID 464
+ + + + G +FL ++ + + G G S+Q GV RTNCID
Sbjct: 290 EGVHFNF-FKEGGILEGDTRKKFL-GLVEQALLSFGYHGPG------SLQSGVIRTNCID 341
Query: 465 CLDRTNAAQFVIGKRALGEQLHAMGIIEEKFLEYDSDIVNILTELFHDHGDTIALQYGGS 524
CLDRTN +QF++G+ L +QL I ++K + L++D+G+++++QY GS
Sbjct: 342 CLDRTNISQFIMGEIILEKQLSHFDIEDKKHFCEQAKC------LWYDNGNSLSMQYSGS 395
Query: 525 HLVNTMETYRKINQWSSHSRDMVESIKRFYSN 556
+ + RK RD + +R++ N
Sbjct: 396 FALKSHFLSRKRQGVVDRLRDGIIGFQRYFIN 427
>Hs14747866 [U] KOG0566 Inositol-145-triphosphate 5-phosphatase (synaptojanin)
INP51/INP52/INP53 family
Length = 1496
Score = 117 bits (293), Expect = 8e-26
Identities = 116/462 (25%), Positives = 194/462 (41%), Gaps = 50/462 (10%)
Query: 110 TACYYLVVITEMSQVAVLGGHSIYHIDDTELVPITKSTKKRDSTELRFIQSFQNLKLSKT 169
T+ +LV++T + V + IY I T+ P+ + K+ + + + + + S
Sbjct: 74 TSLSFLVLVTGCTSVGRIPDAEIYKITATDFYPLQEEAKEEER-----LIALKKILSSGV 128
Query: 170 FYFSYTFDITNTLQTNILRQKFLSVGRSDIEVPPGIPDYNEMFMWNSYLLDPIFSCIDTV 229
FYFS+ D + + QK + D ++ F WN L P+ +
Sbjct: 129 FYFSWPND-GSRFDLTVRTQK-----QGDDS-----SEWGNSFFWNQLLHVPLRQHQVSC 177
Query: 230 YDWFQPIIHGFIDQVNVSLFGKSIYITLIGRRSHYFAGARFLKRGVNNKGYVANEVETEQ 289
DW II G + V K L+ R S G RF RGVN+ G+V+N VETEQ
Sbjct: 178 CDWLLKIICGVVTIRTVYASHKQAKACLVSRVSCERTGTRFHTRGVNDDGHVSNFVETEQ 237
Query: 290 IVADMSLTSFHSPARGFFDSDKYTSFVQHRGSIPLFWSQEASNLTAKPPISINITDPFYS 349
++ + D +SFVQ RGS+PLFW Q + + +
Sbjct: 238 MI---------------YMDDGVSSFVQIRGSVPLFWEQPGLQVGSHHLRLHRGLEANAP 282
Query: 350 AAAKHFDKLFQRYGGGTIQILNLIKTKEKNPRETKLGEEFERCIKYLNQFLPDIKKLEYK 409
A +H L ++YG ++NL+ ++ E L F++ + + + D + +
Sbjct: 283 AFDRHMVLLKEQYGQQV--VVNLLGSR---GGEEVLNRAFKKLL-WASCHAGDTPMINFD 336
Query: 410 AWDMSKASKSHGQMVIEFLEKYAKETVETTGIFHNGKDFQSTSVQEGVCRTNCIDCLDRT 469
+K K + + L K E +F G++ S Q+G R NC+DCLDRT
Sbjct: 337 FHQFAKGGKL--EKLETLLRPQLKLHWEDFDVFTKGENV-SPRFQKGTLRMNCLDCLDRT 393
Query: 470 NAAQFVIGKRALGEQLHAMGIIEEKFLEYDSDIVNILTELFHDHGDTIALQYGGSHLVNT 529
N Q I L QL +G+ + ++ V ++ +G +++ + GS +
Sbjct: 394 NTVQSFIALEVLHLQLKTLGLSSKPIVD---RFVESFKAMWSLNGHSLSKVFTGSRALEG 450
Query: 530 METYRKINQWSSHSRDMVESIKRFYSNSFVDAQRQEAINLFL 571
K+ +D S+ R ++F D +QEAI L L
Sbjct: 451 KAKVGKL-------KDGARSMSRTIQSNFFDGVKQEAIKLLL 485
>At3g59770 [I] KOG1888 Putative phosphoinositide phosphatase
Length = 1616
Score = 94.4 bits (233), Expect = 7e-19
Identities = 111/423 (26%), Positives = 167/423 (39%), Gaps = 80/423 (18%)
Query: 128 GGHSIYHIDDTELVPITK-STKKRDSTELRFIQSFQNLKLSKTFYFSYTFDITNTLQTNI 186
GG +Y + +++ V I + + + E + IQ L + YF T DIT + +
Sbjct: 113 GGGCVYTVAESQWVKIPLYNPQPQGKGETKNIQELTELDIDGKHYFCDTRDITRPFPSRM 172
Query: 187 LRQKFLSVGRSDIEVPPGIPDYNEMFMWNSYLLDPIFSCIDTVYDWFQPIIHGFIDQVNV 246
Q PD + F+WN +L P + + + ++ GF +
Sbjct: 173 PLQS---------------PD--DEFVWNRWLSVPFKNI--GLPEHCVILLQGFAEYRPF 213
Query: 247 SLFGK-SIYITLIGRRSHYFAGARFLKRGVNNKGYVANEVETEQIVADMSLTSFHSPARG 305
G+ + L+ RRS G R+L RG+N+ NEVE EQ+V P R
Sbjct: 214 GSSGQLEGIVALMARRSRLHPGTRYLARGINSCSGTGNEVECEQLV--------WIPKRN 265
Query: 306 FFDSDKYTSFVQHRGSIPLFWSQEASNLTAKPPISINITDPFYSAAAKHFDKLFQRYGGG 365
S + S++ RG+IP++W E A+ I + DP Y + +++ +L +RY
Sbjct: 266 G-QSIAFNSYIWRRGTIPIWWGAELKMTAAEAEIYVADRDP-YKGSTEYYQRLSKRYDTR 323
Query: 366 TIQI----------------LNLIKTKEKNPRETKLGEEFERCIKYLNQFLPDIKKLEYK 409
+ +NL+++ E E L + FE + F+ KL Y
Sbjct: 324 NLDAPVGENQKKKAFVPIVCVNLLRSGE-GKSECILVQHFEESMN----FIKSSGKLPYT 378
Query: 410 A-----WDMSKASKSHG-QMVIEFLEKYAKETVETTGIFHNG--------KD-------- 447
+D + K G Q IE L Y K GI KD
Sbjct: 379 RVHLINYDWHASVKLKGEQQTIEGLWMYLKSPTMAIGISEGDYLPSRQRLKDCRGEVICI 438
Query: 448 ------FQSTSVQEGVCRTNCIDCLDRTNAAQFVIGKRALGEQLHAMGIIEEKFLEYDSD 501
F S Q GV R NC D LDRTNAA F G + EQ +GI + L Y +
Sbjct: 439 DDIEGAFCLRSHQNGVIRFNCADSLDRTNAASFFGGLQVFVEQCRRLGISLDTDLGYGHN 498
Query: 502 IVN 504
VN
Sbjct: 499 SVN 501
>SPBC577.13 [U] KOG0566 Inositol-145-triphosphate 5-phosphatase (synaptojanin)
INP51/INP52/INP53 family
Length = 889
Score = 91.3 bits (225), Expect = 6e-18
Identities = 102/390 (26%), Positives = 166/390 (42%), Gaps = 41/390 (10%)
Query: 210 EMFMWNSYL---LDPIFSCIDTVYDWFQPIIHGFIDQVNVSLFGKSIYITLIGRRSHYFA 266
+++ WN +L LD FS + + ++H F V +F S+ +++I + S Y +
Sbjct: 202 DIYCWNRFLITELDNHFSEAHILEKFPNLLLHCFRGYVE-RMFIDSMSMSIISKVSSYGS 260
Query: 267 GARFLKRGVNNKGYVANEVETEQIVADMSLTSFHSPARGFFDSDKYTSFVQHRGSIPLFW 326
+ G+++ Y + VETE IV +++ T F SFVQ RG++P FW
Sbjct: 261 RQTYPPSGIDDSSYCSMFVETEFIV-EIAQTVF--------------SFVQVRGTVPCFW 305
Query: 327 SQEASNLTAKPPISINITDPFYSAAAKHFDKLFQRYGGGTIQILNLIKTKEKNPRETKLG 386
++ S+ + + S HF KL++ YG I +++L++TK E L
Sbjct: 306 EEQFSSWYGPSISFLRSSQASQSLFNFHFSKLYKAYGD--IYVIDLLQTKGF---EASLY 360
Query: 387 EEFERCIKYLNQFLPDIKKLEYKAWDMSKASKSHGQMVIEFLEKYAKETVETTGIFHNGK 446
E ++ + L F +KK + A + L KE T N
Sbjct: 361 EAYKHHLMLL-PFPAVVKKFHFTP---DPARPDIDPRLETDLADDLKEMGYTQKSIEND- 415
Query: 447 DFQSTSVQEGVCRTNCIDCLDRTNAAQFVIGKRALGEQLHAMGI-IEEKFLEYDSDIVNI 505
S Q+GV R N +DCL RTN Q+ I + L + + I + LEY
Sbjct: 416 --MLESFQKGVFRINDLDCLGRTNVIQYQISRLVLKDIFFNLQIGVTFNILEY------- 466
Query: 506 LTELFHDHGDTIALQYGGSHLVNTMETYRKINQWSSHSRDMVESIKRFYSNSFVDAQRQE 565
L L+ ++GD IA G + + T R + D+ +S R Y + D + Q
Sbjct: 467 LRHLWSNNGDAIAKLITGVGSIGSSATRRGRKSIAGSLSDISKSFGRMYVGRYPDVESQN 526
Query: 566 AINLFLGHYIWSKDQPMLWDMSTDFYLHNL 595
AI L LG + P+L S Y+ +
Sbjct: 527 AILLLLG--CFPNQSPVLISESVSSYIQGV 554
>ECU08g1420 [U] KOG0566 Inositol-145-triphosphate 5-phosphatase (synaptojanin)
INP51/INP52/INP53 family
Length = 453
Score = 84.3 bits (207), Expect = 7e-16
Identities = 81/318 (25%), Positives = 134/318 (41%), Gaps = 57/318 (17%)
Query: 254 YITLIGRRSHYFAGARFLKRGVNNKGYVANEVETEQIVADMSLTSFHSPARGFFDSDKYT 313
++ L+ S G R+L RG++ +G + V+T + T F
Sbjct: 180 HMKLLSLVSSNRVGTRYLCRGIDEEGNASLFVKTHFQTKRNNSTIF-------------- 225
Query: 314 SFVQHRGSIPLFWSQEASNLTAKPPISINITDPFYSAAAKHFDKLFQRYGGGTIQILNLI 373
F RGS+P+FWSQ + AK I A AKHF KL + YG I ++NL+
Sbjct: 226 DFTIIRGSVPIFWSQRGHGIPAKVNI-YGEDGAVKKAFAKHFKKLRREYG--KIYVINLL 282
Query: 374 KTKEKNPRETKLGEEFERCIKYLNQFLPDIKKLEYKAWDMSKASKSHGQMVIEFLEKYAK 433
K+ E +L F R + D++ + Y +D++ + ++ + +FL +
Sbjct: 283 GEKKY---EKQLTSHFSRLL--------DLENIPYTTFDLNAHASNYDDL--KFLLYFK- 328
Query: 434 ETVETTGIFHNGKDFQSTSVQEGVCRTNCIDCLDRTNAAQFVIGKRALGEQLHAMGIIEE 493
Q Q+ V R NC+DCLDRTN AQ +I M E+
Sbjct: 329 --------------LQGIGQQDIVFRVNCLDCLDRTNVAQSLI----------CMFYFEK 364
Query: 494 KFLEYDSDIVNILTELFHDHGDTIALQYGGSHLVNTMETYRKINQWSSHSRDMVESIKRF 553
+ D + + + E + D+G++++ Y GS + + + + D V S R
Sbjct: 365 --VVCDGNALKRMQECWADNGNSLSNLYTGSDAMKRELALKGRRSFVGYMDDFVISATRL 422
Query: 554 YSNSFVDAQRQEAINLFL 571
+ F D Q+ IN+ L
Sbjct: 423 INGRFTDRQKHSIINVLL 440
>SPAC3C7.01c [I] KOG1889 Putative phosphoinositide phosphatase
Length = 323
Score = 75.5 bits (184), Expect = 3e-13
Identities = 63/222 (28%), Positives = 104/222 (46%), Gaps = 17/222 (7%)
Query: 353 KHFDKLFQRYGGGTIQILNLIKTKEKNPRETKLGEEFERCIKYLNQFLPDIKKLEYKAWD 412
KHF +L YG + ++NL+ K RE L FE+ K N+ P L Y +D
Sbjct: 4 KHFQELANDYGDNLV-VVNLLDQKG---REAPLRSGFEKLCKR-NKNPP----LSYVYYD 54
Query: 413 MSKASKSHGQMVIEFLEKYAKETVETTGIFHNGKDFQSTSVQEGVCRTNCIDCLDRTNAA 472
K + + + ++ E G ++ ++T++Q RTNC+DCLDRTN
Sbjct: 55 YHKQGSRNLPLFLAEIQSLLIE-----GKYYAEHGSKTTAMQTNFVRTNCMDCLDRTNVI 109
Query: 473 QFVIGKRALGEQLHAMGII--EEKFLEYDSDIVNILTELFHDHGDTIALQYGGSHLVNTM 530
Q I + L QLH +G++ E EYDS + + ++ + GD I+ Y G+ +
Sbjct: 110 QTSIAQFILNMQLHDIGVLSSSESLEEYDSFLQDFRL-IWANTGDYISDLYTGTPALKGD 168
Query: 531 ETYRKINQWSSHSRDMVESIKRFYSNSFVDAQRQEAINLFLG 572
T +D++ +R+ N+F D Q++ +L LG
Sbjct: 169 VTRHGTRTIFGAFKDLLNCFRRYILNNFFDGMLQDSYDLGLG 210
>YIL002c [U] KOG0566 Inositol-145-triphosphate 5-phosphatase (synaptojanin)
INP51/INP52/INP53 family
Length = 946
Score = 62.0 bits (149), Expect = 4e-09
Identities = 74/339 (21%), Positives = 139/339 (40%), Gaps = 58/339 (17%)
Query: 169 TFYFSYTFDITNTLQTNILRQKF-LSVGRSDIEVPPGIPDYNEMFMWNSYLLDPIFSCID 227
TFY+S FDI+N ++ + L +V D+ F+WN+ L + +
Sbjct: 159 TFYYSRDFDISNIVKNHGLSHNLEYTVDNQDLS-----------FIWNANLASEVINWRS 207
Query: 228 TVYD----------WFQPIIHGFIDQVNVSLFGKSIYITLIGRRSHYFAGARFLKRGVNN 277
+ + + +I G+ + + IT+I R S G++
Sbjct: 208 KISNEEKQLFANAGFLTFVIRGYCKTALIEDGPNTASITIISRISTESKQDTLELEGISE 267
Query: 278 KGYVANEVETEQIVADMSLTSFHSPARGFFDSDKYT-SFVQHRGSIPLFWSQEASNLTAK 336
G V+ VETE +V ++K+ S+ Q GSIPLFW S L
Sbjct: 268 DGRVSLFVETEIVVT----------------TEKFIFSYTQVNGSIPLFWESVESQLLYG 311
Query: 337 PPISINITDPFYSAAA--KHFDKLFQRYGGGTIQILNLIKTKEKNPRETKLGEEFERCIK 394
I + D + A +HFD L +Y G + I+N+IK K ++ + KL ++ C +
Sbjct: 312 KKIKVT-KDSIEAQGAFDRHFDNLTSKY--GVVSIVNIIKPKSES--QEKLALTYKDCAE 366
Query: 395 YLNQFLPDIKKLEYKAWDMSKASKSHGQMVIEFLEKYAKETVE-TTGIFHNGKDFQSTSV 453
I +EY + ++K+ ++ + + ++ + + GI+ +
Sbjct: 367 SKG---IKITNIEYSSSVLTKSPHKLLYLLKQDIYEFGAFAYDISRGIYF--------AK 415
Query: 454 QEGVCRTNCIDCLDRTNAAQFVIGKRALGEQLHAMGIIE 492
Q GV R + D +++ N + ++ K L + + + E
Sbjct: 416 QTGVLRISAFDSIEKPNTVERLVSKEVLELTTNEIDVFE 454
Database: KOG eukaryal database 04/03
Posted date: Apr 14, 2003 1:07 PM
Number of letters in database: 30,389,216
Number of sequences in database: 60,738
Lambda K H
0.318 0.135 0.395
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 52,375,304
Number of Sequences: 60738
Number of extensions: 2322775
Number of successful extensions: 6749
Number of sequences better than 1.0e-05: 33
Number of HSP's better than 0.0 without gapping: 16
Number of HSP's successfully gapped in prelim test: 17
Number of HSP's that attempted gapping in prelim test: 6568
Number of HSP's gapped (non-prelim): 45
length of query: 866
length of database: 30,389,216
effective HSP length: 115
effective length of query: 751
effective length of database: 23,404,346
effective search space: 17576663846
effective search space used: 17576663846
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)