ORF STATUS Function Best COG Functional category Pathways and functional systems
r_klactV0618 good U KOG3983 Intracellular trafficking, secretion, and vesicular transport Golgi protein
Only best alignment is shown:
BLASTP 2.2.3 [May-13-2002]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= r_klactV0618 218196 217225 -324
(324 letters)
Database: KOG eukaryal database 04/03
60,738 sequences; 30,389,216 total letters
Searching..................................................done
Color Key for Alignment Scores: 
Score E
Sequences producing significant alignments: (bits) Value
YDR372c [U] KOG3983 Golgi protein 486 e-137
7295987 [U] KOG3983 Golgi protein 194 1e-49
CE24362 [U] KOG3983 Golgi protein 193 2e-49
Hs11545859 [U] KOG3983 Golgi protein 192 7e-49
Hs21361716 [U] KOG3983 Golgi protein 190 2e-48
HsM8922589 [U] KOG3983 Golgi protein 130 3e-30
SPAC5D6.13 [U] KOG3983 Golgi protein 87 3e-17
>YDR372c [U] KOG3983 Golgi protein
Length = 345
Score = 486 bits (1252), Expect = e-137
Identities = 246/343 (71%), Positives = 284/343 (82%), Gaps = 20/343 (5%)
Query: 2 SLQRRRVNKGDT--TESIPQI------------------DNEHDHKIVYDEQEAKLRDNT 41
+LQRRRVN+ D+ T SI DN + KI YD +E+KLRDN
Sbjct: 3 TLQRRRVNRADSGDTSSIHSSANNTKGDKIANIAVDGDDDNGTNKKIAYDPEESKLRDNI 62
Query: 42 SVPKLTLMEEVLLMGLKDKQGYLSFWNDNISYALRGCILIELALRGKIRCVDDPARKRYD 101
++P LTLMEEVLLMGL+D++GYLSFWND+ISYALRGCI+IELALRGKIR +DD ARKR+D
Sbjct: 63 NIPTLTLMEEVLLMGLRDREGYLSFWNDSISYALRGCIIIELALRGKIRILDDSARKRFD 122
Query: 102 VSERLIEVIDGSKTGEVLLDESLSLMKNDPPTSIVGWIDLLSGETWNLLKINYQLKQVRE 161
+SERLIEVID SKTGEVLLDE+L LMKND P SI WIDLLSGETWNLLKINYQLKQVRE
Sbjct: 123 LSERLIEVIDSSKTGEVLLDETLQLMKNDEPLSISNWIDLLSGETWNLLKINYQLKQVRE 182
Query: 162 RLAKGLVDKGVLRTEMKNFFLFDMATHPITDTTCKESIKRRILSILVSRNAELTYNTYFP 221
RLAKGLVDKGVLRTEMKNFFLFDMATHPI D +CKE+IKRR+LS+LVSRN EL+YN YFP
Sbjct: 183 RLAKGLVDKGVLRTEMKNFFLFDMATHPIADASCKEAIKRRVLSVLVSRNMELSYNEYFP 242
Query: 222 QDVSFKYIRTLSLICGAYGANVLENVLATLDYEVRDTGFARADEILAQFSEFPFPLDKQT 281
+ SFK IRTL+LICG+YGANVLENVL TL+YE RD +RA+EI+AQFS++PF L+K+T
Sbjct: 243 ETTSFKIIRTLALICGSYGANVLENVLTTLEYEKRDKAISRAEEIMAQFSQYPFDLEKET 302
Query: 282 STGVSVNLNKEISQELNNHPGSDLQLEVVAGVFEVFSRMDTLL 324
GVSVNLNKE+ +E+ N+PG DLQLEV+AGVFEVFSRMD LL
Sbjct: 303 ELGVSVNLNKEVKEEIENNPGHDLQLEVIAGVFEVFSRMDMLL 345
>7295987 [U] KOG3983 Golgi protein
Length = 294
Score = 194 bits (493), Expect = 1e-49
Identities = 115/249 (46%), Positives = 154/249 (61%), Gaps = 12/249 (4%)
Query: 21 DNEHDHKIVYDEQEAKLRDNTSVP-KLTLMEEVLLMGLKDKQGYLSFWNDNISYALRGCI 79
D+ D +QE + D S +LTLMEEVLL+GLKDK+GY SFWND IS LRGCI
Sbjct: 30 DDNQDALDNLKDQEDNIDDGDSKETRLTLMEEVLLLGLKDKEGYTSFWNDCISSGLRGCI 89
Query: 80 LIELALRGKIRCVDDPARKRYDVSERLIEVIDGSKTGEVLLDESLSLMK-NDPPTSIVGW 138
LIEL LRG++ R+R + +LI D +TG+VLLDE+L +K DPP ++ W
Sbjct: 90 LIELGLRGRVMIEKSGMRRRGLCTRKLILKSD-QQTGDVLLDEALKHIKETDPPETVQSW 148
Query: 139 IDLLSGETWNLLKINYQLKQVRERLAKGLVDKGVLRTEMKNFFLFDMATHPITDTTCKES 198
I+ LSGETWN LK+ YQLK VRERLAK LV+KGVL TE +NF LFDM THP++D K
Sbjct: 149 IEYLSGETWNPLKLRYQLKNVRERLAKNLVEKGVLTTEKQNFLLFDMTTHPLSDNVVKCR 208
Query: 199 IKRRILSILVSRNAELTYNTYFPQDVSFKYIRTLSLICGAYGANVLENVLATLDYEVRDT 258
+ ++I ++S+ + D R L+LI A+ ++V+EN A L+ + +
Sbjct: 209 LVKKIQDSVLSK---------WVNDPQRMDKRMLALIFLAHASDVIENAFAPLNDDDYEV 259
Query: 259 GFARADEIL 267
R E+L
Sbjct: 260 AMKRVRELL 268
>CE24362 [U] KOG3983 Golgi protein
Length = 301
Score = 193 bits (491), Expect = 2e-49
Identities = 109/258 (42%), Positives = 158/258 (60%), Gaps = 21/258 (8%)
Query: 3 LQRRRVNKGDTTESIPQIDNEHDHKIVYDEQEAKLRDNTSVPKLTLMEEVLLMGLKDKQG 62
+QRRR + TE + + + Q + DN +LTLME++LL+GLKD++G
Sbjct: 7 VQRRRKAEEPVTEKVDEASGD-------SAQSSDQEDNDKGTRLTLMEQILLLGLKDREG 59
Query: 63 YLSFWNDNISYALRGCILIELALRGKIRCVDDPARKRYDVSERLIEVIDGSKTGEVLLDE 122
Y SFWND IS LRGC+LIEL LRG+I+ ++ +R ++ R + V TG+V+LDE
Sbjct: 60 YTSFWNDCISSGLRGCVLIELVLRGRIQ-LEGGGMRRKNLLNRKVTVKSSEPTGDVILDE 118
Query: 123 SLSLMKN-DPPTSIVGWIDLLSGETWNLLKINYQLKQVRERLAKGLVDKGVLRTEMKNFF 181
+L MK +PP ++ WI+ LSGETWN LK+ YQL+ VRERLAK LV+KGVL T+ +NF
Sbjct: 119 ALRHMKETNPPETVTSWIEYLSGETWNPLKLRYQLRNVRERLAKNLVEKGVLTTDKQNFL 178
Query: 182 LFDMATHPITDTTCKESIKRRILSILVSRNAELTYNTYFPQDVSFKYIRTLSLICGAYGA 241
LF++ THP++D K + + + ++ + + DV + LSLI A+ +
Sbjct: 179 LFEITTHPLSDGNQKTKLIKEVQEAVLGK---------WTNDVHRMDKKMLSLIVLAHAS 229
Query: 242 NVLENVLATL---DYEVR 256
+VLEN A L DYEV+
Sbjct: 230 DVLENAFAPLSDQDYEVK 247
>Hs11545859 [U] KOG3983 Golgi protein
Length = 298
Score = 192 bits (487), Expect = 7e-49
Identities = 110/247 (44%), Positives = 159/247 (63%), Gaps = 11/247 (4%)
Query: 22 NEHDHKIVYDEQEAKLRDNTSVPKLTLMEEVLLMGLKDKQGYLSFWNDNISYALRGCILI 81
+E D + DEQ+ + ++ +LTLMEEVLL+GLKD++GY SFWND IS LRGC+LI
Sbjct: 36 SEDDAQSRRDEQDDDDKGDSKETRLTLMEEVLLLGLKDREGYTSFWNDCISSGLRGCMLI 95
Query: 82 ELALRGKIRCVDDPARKRYDVSERLIEVIDGSKTGEVLLDESLSLMKN-DPPTSIVGWID 140
ELALRG+++ R++ ++ ++I D + TG+VLLDE+L +K PP ++ WI+
Sbjct: 96 ELALRGRLQLEACGMRRKSLLTRKVICKSD-APTGDVLLDEALKHVKETQPPETVQNWIE 154
Query: 141 LLSGETWNLLKINYQLKQVRERLAKGLVDKGVLRTEMKNFFLFDMATHPITDTTCKESIK 200
LLSGETWN LK++YQL+ VRERLAK LV+KGVL TE +NF LFDM THP+T+ K+ +
Sbjct: 155 LLSGETWNPLKLHYQLRNVRERLAKNLVEKGVLTTEKQNFLLFDMTTHPLTNNNIKQRLI 214
Query: 201 RRILSILVSRNAELTYNTYFPQDVSFKYIRTLSLICGAYGANVLENVLATLDYEVRDTGF 260
+++ ++ + + D R L+LI A+ ++VLEN A L E D
Sbjct: 215 KKVQEAVLDK---------WVNDPHRMDRRLLALIYLAHASDVLENAFAPLLDEQYDLAT 265
Query: 261 ARADEIL 267
R ++L
Sbjct: 266 KRVRQLL 272
>Hs21361716 [U] KOG3983 Golgi protein
Length = 285
Score = 190 bits (483), Expect = 2e-48
Identities = 105/224 (46%), Positives = 150/224 (66%), Gaps = 11/224 (4%)
Query: 45 KLTLMEEVLLMGLKDKQGYLSFWNDNISYALRGCILIELALRGKIRCVDDPARKRYDVSE 104
+LTLMEEVLL+GLKDK+GY SFWND IS LRG ILIELA+RG+I ++ P ++ + +
Sbjct: 45 RLTLMEEVLLLGLKDKEGYTSFWNDCISSGLRGGILIELAMRGRIY-LEPPTMRKKRLLD 103
Query: 105 RLIEVIDGSKTGEVLLDESLSLMKNDPPTSIVG-WIDLLSGETWNLLKINYQLKQVRERL 163
R + + S TG+VLLDE+L +K PT V WI+LL+GETWN K+ YQL+ VRER+
Sbjct: 104 RKVLLKSDSPTGDVLLDETLKHIKATEPTETVQTWIELLTGETWNPFKLQYQLRNVRERI 163
Query: 164 AKGLVDKGVLRTEMKNFFLFDMATHPITDTTCKESIKRRILSILVSRNAELTYNTYFPQD 223
AK LV+KG+L TE +NF LFDM THP+T+TT K+ + +++ ++ R + D
Sbjct: 164 AKNLVEKGILTTEKQNFLLFDMTTHPVTNTTEKQRLVKKLQDSVLER---------WVND 214
Query: 224 VSFKYIRTLSLICGAYGANVLENVLATLDYEVRDTGFARADEIL 267
RTL+L+ A+ ++VLENV ++L + D RA +++
Sbjct: 215 PQRMDKRTLALLVLAHSSDVLENVFSSLTDDKYDVAMNRAKDLV 258
>HsM8922589 [U] KOG3983 Golgi protein
Length = 201
Score = 130 bits (326), Expect = 3e-30
Identities = 73/184 (39%), Positives = 115/184 (61%), Gaps = 11/184 (5%)
Query: 85 LRGKIRCVDDPARKRYDVSERLIEVIDGSKTGEVLLDESLSLMKNDPPTSIVG-WIDLLS 143
+RG+I ++ P ++ + +R + + S TG+VLLDE+L +K PT V WI+LL+
Sbjct: 1 MRGRIY-LEPPTMRKKRLLDRKVLLKSDSPTGDVLLDETLKHIKATEPTETVQTWIELLT 59
Query: 144 GETWNLLKINYQLKQVRERLAKGLVDKGVLRTEMKNFFLFDMATHPITDTTCKESIKRRI 203
GETWN K+ YQL+ VRER+AK LV+KG+L TE +NF LFDM THP+T+TT K+ + +++
Sbjct: 60 GETWNPFKLQYQLRNVRERIAKNLVEKGILTTEKQNFLLFDMTTHPVTNTTEKQRLVKKL 119
Query: 204 LSILVSRNAELTYNTYFPQDVSFKYIRTLSLICGAYGANVLENVLATLDYEVRDTGFARA 263
++ R + D RTL+L+ A+ ++VLENV ++L + D RA
Sbjct: 120 QDSVLER---------WVNDPQRMDKRTLALLVLAHSSDVLENVFSSLTDDKYDVAMNRA 170
Query: 264 DEIL 267
+++
Sbjct: 171 KDLV 174
>SPAC5D6.13 [U] KOG3983 Golgi protein
Length = 99
Score = 87.0 bits (214), Expect = 3e-17
Identities = 47/101 (46%), Positives = 68/101 (66%), Gaps = 3/101 (2%)
Query: 225 SFKYIRTLSLICGAYGANVLENVLATLDYEVRDTGFARADEILAQFSEFPFPLDKQTSTG 284
SF+ +RT++L C +Y ANVLEN L L+YE R+ F+R DE+L FS++PF D S+
Sbjct: 1 SFRCLRTVALACSSYAANVLENALDNLNYEDREKAFSRVDELLCDFSQWPF--DLHASSS 58
Query: 285 VSVNLNKEISQELNNHPGSDLQ-LEVVAGVFEVFSRMDTLL 324
V NL + IS+EL++ L +EVVA V +VF+ +D+LL
Sbjct: 59 VGANLPELISEELSSVKEEQLLFIEVVAAVLQVFTHLDSLL 99
Database: KOG eukaryal database 04/03
Posted date: Apr 14, 2003 1:07 PM
Number of letters in database: 30,389,216
Number of sequences in database: 60,738
Lambda K H
0.319 0.137 0.389
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 18,817,750
Number of Sequences: 60738
Number of extensions: 780894
Number of successful extensions: 2061
Number of sequences better than 1.0e-05: 7
Number of HSP's better than 0.0 without gapping: 7
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 2041
Number of HSP's gapped (non-prelim): 7
length of query: 324
length of database: 30,389,216
effective HSP length: 106
effective length of query: 218
effective length of database: 23,950,988
effective search space: 5221315384
effective search space used: 5221315384
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)