ORF STATUS Function Best COG Functional category Pathways and functional systems
r_klactV0879 good L KOG1968 Replication, recombination and repair Replication factor C, subunit RFC1 (large subunit)
Only best alignment is shown:
BLASTP 2.2.3 [May-13-2002]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= r_klactV0879 308568 306322 -749
(749 letters)
Database: KOG eukaryal database 04/03
60,738 sequences; 30,389,216 total letters
Searching..................................................done
Color Key for Alignment Scores: 
Score E
Sequences producing significant alignments: (bits) Value
YOR144c [L] KOG1968 Replication factor C subunit RFC1 (large sub... 239 9e-63
SPBC947.11c [L] KOG1968 Replication factor C subunit RFC1 (large... 64 6e-10
Hs19923605 [L] KOG1968 Replication factor C subunit RFC1 (large ... 53 2e-06
>YOR144c [L] KOG1968 Replication factor C subunit RFC1 (large subunit)
Length = 791
Score = 239 bits (611), Expect = 9e-63
Identities = 195/697 (27%), Positives = 329/697 (46%), Gaps = 76/697 (10%)
Query: 105 IILLDESPVKVDSANRFDASHITSDGLQAAKNSNIASFLNMERS-------------TVQ 151
I++ D+SP + ++ S D + S I S L ER+ T +
Sbjct: 93 IVISDKSPKSETNCSKIALSQEHEDDISIISTSRIKSSLLNERASKIKNFLKHETTDTFK 152
Query: 152 RQNKISKEQVLHAPLPHIQHTPHYILGKQN------SISLHKKVVKPLDLSFNASEYSFL 205
R N ISK + PLP H + +G + I L + + PL+ +F S+Y L
Sbjct: 153 RLNSISKLNEIEPPLP--LHQSIFPVGDKELSDRSVDIPLPFRTIPPLNHNFLPSDYESL 210
Query: 206 VNSDKPDGSKEALNINDRISYSDDTTNTQLWTSLFKPTSIEDVLIDSDTKSSVREWFKDA 265
+ + + + T W LFKP +++ VLI+ K ++ W + +
Sbjct: 211 KDKNSASCIPVRYQAPVLLGTNIKRNTTLTWPQLFKPVTLKQVLIEPKLKLRIKNWIETS 270
Query: 266 FDLLNRKTDRSALYNR----KVDG---DLDNFIVDD---------SFLGSGD-DTSVKQF 308
F L + T R+ L NR K G +L NFIV D F +G+ ++S+ +F
Sbjct: 271 FHTLEKPTLRNRLLNRINPNKQQGSGDELANFIVPDLEEDENLRPDFYRNGEANSSLSEF 330
Query: 309 VPLIILYGG-IGKNTLIDVLM-----DEQDAHIFEINCSMNRAKRDISDMLHDFATTKYV 362
VPL+IL+G IGK TLI +M D+ I+E+N +MNR+K+D+ D+L DF TT YV
Sbjct: 331 VPLMILHGNSIGKKTLIQTIMREIAGDDNSYQIYEVNSNMNRSKKDLLDILLDFTTTHYV 390
Query: 363 KDTQSK----GIILFDDVDVLLTESDKFFWNSVHATLIVSRRPVVITCGDYRFIPSNLLE 418
KD+ + G++LF+DVDVL E D+ +W + SRRP+V+TC D +PS L+
Sbjct: 391 KDSSKRKSDYGLVLFNDVDVLFKEHDRGYWAMISKLCEFSRRPLVLTCKDLSLVPSELIA 450
Query: 419 VAEEQHSIFNIKSAPKQQIMEYTSRCLEQKGIEXXXXXXXXXXXXXXYHIRKCLMDLQWV 478
+A EQ+S+F+ K + + ++ L+ IE IRKCLM LQ+
Sbjct: 451 LASEQNSLFHTKKISTSTVYAFLTKYLKSLEIEVCDDWLRDVVKQNNADIRKCLMHLQFW 510
Query: 479 C--TKPGVVPIKDSHFPRNQNDNTENIKDAWLKLDFSSSYDVIQNCIEGKSFVKDDIDLT 536
C T+ ++ K + P + ++KD D S DVI +S V+ +ID T
Sbjct: 511 CVDTEADLISSK-NRLPVLTSTLGSSVKDISQLTDLLSINDVIGQATLNRSMVRQEIDST 569
Query: 537 ------LNYAKHQISNDE-ETSYDVVWDYVEHLWDINHNTLFPWEKQMQSLMEEKCK--- 586
+N + Q +DE + +D V DY HL D N L P+E + ++E+ +
Sbjct: 570 TMTPEKVNTFQDQNLDDEMKLKFDYVIDYKLHLNDPNRQPLLPFELNIYQHIQEQLEARY 629
Query: 587 QFLRFNDNEDVNVVAHDKVSICVNEMIKYLKTRVNNSPQGNVLTMLGNTRSSRRKTGVLK 646
++R ++ N ++ + +L +R+ P+ + L TR+S++ + +L
Sbjct: 630 SYVREANHRLDNEYLVNRFKKMTESTLNFLASRI---PKYDHLQSARRTRNSKKISDILN 686
Query: 647 DYR--LKSEDNSDAFELDFINNLALEFSATHKLKDISRWYLPFMSRIAESETEIKNKNVS 704
++ E ++ E+D + SAT + I PF+ IA+S+ +KN+N
Sbjct: 687 QFKGIYNDETLNENAEIDLL-------SAT--TQQIKAEINPFVFEIAKSDANVKNENKQ 737
Query: 705 LFQRYREHYGPEYNANDIIQEMVDKRLILAAFFRGSP 741
+F+ + E+ E D++ ++ + ++ +F P
Sbjct: 738 IFELHSENVS-ERRYKDLVYQLSQEGVLKNVWFNADP 773
>SPBC947.11c [L] KOG1968 Replication factor C subunit RFC1 (large subunit)
Length = 920
Score = 64.3 bits (155), Expect = 6e-10
Identities = 53/244 (21%), Positives = 104/244 (41%), Gaps = 38/244 (15%)
Query: 235 LWTSLFKPTSIEDVLIDSDTKSSVREWFKD-------------AFDLLNRKTDRSALYNR 281
LW S + P+ +D S S + +W + + + T S ++
Sbjct: 324 LWVSKYAPSKTQDCCAFSQCLSKIADWLRSCRLTKPESSSVPPSSSISRSSTIHSCTSSK 383
Query: 282 KVDGDLDNFIVDDSFLGSGDDT--------------SVKQFVPLIILYG--GIGKNTLID 325
+ + L + + DD+ + QF +++ G GIGK + +
Sbjct: 384 RNEDSLSESDFEPDIIEEEDDSDEFNPSVSRKKAKLTSSQFSNWMLVTGVTGIGKTSCLY 443
Query: 326 VLMDEQDAHIFEINCSMNRAKRDISDMLHDFATTKYVKDTQSKG----IILFDDVDVLLT 381
+ E + + EI+ M R+ +++ + + + + V ++ +IL ++VD+L
Sbjct: 444 AICRELNFEVVEIHPGMRRSGKELLERIGELTQSHIVDKSRLNNTPDILILLEEVDILF- 502
Query: 382 ESDKFFWNSVHATLIVSRRPVVITCGDYRFIPSNLLEVAEEQHSIFNIKSAPKQQIMEYT 441
+ D+ FW +V + S+RPVV+TC + F+PS L +E H I +S + +Y
Sbjct: 503 QDDRGFWQAVSTLIEKSKRPVVMTCNETDFLPSAFL---QEDH-IVQFQSISSALLTDYI 558
Query: 442 SRCL 445
S L
Sbjct: 559 SSVL 562
>Hs19923605 [L] KOG1968 Replication factor C subunit RFC1 (large subunit)
Length = 1204
Score = 52.8 bits (125), Expect = 2e-06
Identities = 54/213 (25%), Positives = 89/213 (41%), Gaps = 18/213 (8%)
Query: 159 EQVLHAPLPHIQHTPHYILGKQNSISLHKKVVKPLDLSFNASEYSFLVNSDKPDGSKEAL 218
+Q L A + H + T ++ +NS S KK P + S N + N + SK
Sbjct: 984 KQELEADVSH-KETKRKLVEAENSKSKRKK---PNEYSKNLEK----TNRKSEELSKRNN 1035
Query: 219 NINDRISYSDDT-TNTQLWTSLFKPTSIEDVLIDSDTKSSVREWFKDAFDLLNRKTDRSA 277
+ ++ S D+ T LWT ++P + +++ + + W KD R+ +
Sbjct: 1036 SSGIKLDSSKDSGTEDMLWTEKYQPQTASELIGNELAIKKLHSWLKD----WKRRAELEE 1091
Query: 278 LYNRKVDGDL--DNFIVDDSFLGSGDDTSVKQFVPLIILYG--GIGKNTLIDVLMDEQDA 333
N K D ++F F GS DD + +++ G G+GK + E
Sbjct: 1092 RQNLKGKRDEKHEDFSGGIDFKGSSDDEEESRLCNTVLITGPTGVGKTAAVYACAQELGF 1151
Query: 334 HIFEINCSMNRAKRDISDMLHDFATTKYVKDTQ 366
IFE+N S R+ R I L + AT + D Q
Sbjct: 1152 KIFEVNASSQRSGRQILSQLKE-ATQSHQVDKQ 1183
Database: KOG eukaryal database 04/03
Posted date: Apr 14, 2003 1:07 PM
Number of letters in database: 30,389,216
Number of sequences in database: 60,738
Lambda K H
0.316 0.133 0.382
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 45,824,815
Number of Sequences: 60738
Number of extensions: 2057057
Number of successful extensions: 6355
Number of sequences better than 1.0e-05: 3
Number of HSP's better than 0.0 without gapping: 1
Number of HSP's successfully gapped in prelim test: 2
Number of HSP's that attempted gapping in prelim test: 6342
Number of HSP's gapped (non-prelim): 3
length of query: 749
length of database: 30,389,216
effective HSP length: 114
effective length of query: 635
effective length of database: 23,465,084
effective search space: 14900328340
effective search space used: 14900328340
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.6 bits)