ORF STATUS Function Best COG Functional category Pathways and functional systems
r_klactV0891 good R KOG3235 General function prediction only Subunit of the major N alpha-acetyltransferase
Only best alignment is shown:
BLASTP 2.2.3 [May-13-2002]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= r_klactV0891 310765 311454 230
(230 letters)
Database: KOG eukaryal database 04/03
60,738 sequences; 30,389,216 total letters
Searching..................................................done
Color Key for Alignment Scores: 
Score E
Sequences producing significant alignments: (bits) Value
YHR013c [R] KOG3235 Subunit of the major N alpha-acetyltransferase 310 8e-85
SPAC15E1.08 [R] KOG3235 Subunit of the major N alpha-acetyltrans... 179 3e-45
Hs14249280 [R] KOG3235 Subunit of the major N alpha-acetyltransf... 170 2e-42
CE18023 [R] KOG3235 Subunit of the major N alpha-acetyltransferase 170 2e-42
Hs10835057 [R] KOG3235 Subunit of the major N alpha-acetyltransf... 169 3e-42
At5g13780 [R] KOG3235 Subunit of the major N alpha-acetyltransfe... 162 5e-40
7294847 [R] KOG3235 Subunit of the major N alpha-acetyltransferase 156 2e-38
Hs7705823 [R] KOG3234 Acetyltransferase (GNAT) family 77 2e-14
7293615 [R] KOG3234 Acetyltransferase (GNAT) family 74 2e-13
At1g03150 [R] KOG3234 Acetyltransferase (GNAT) family 70 2e-12
CE25639 [R] KOG3234 Acetyltransferase (GNAT) family 67 2e-11
YPR131c [R] KOG3234 Acetyltransferase (GNAT) family 67 3e-11
At1g03650 [R] KOG3139 N-acetyltransferase 50 2e-06
ECU06g0460 [R] KOG3235 Subunit of the major N alpha-acetyltransf... 50 3e-06
>YHR013c [R] KOG3235 Subunit of the major N alpha-acetyltransferase
Length = 238
Score = 310 bits (795), Expect = 8e-85
Identities = 168/245 (68%), Positives = 195/245 (79%), Gaps = 22/245 (8%)
Query: 1 MPITIRHATIDDILAMQNANLHNLPENYMLKYYMYHILSWPEASFVATTTD-DVDDIMDQ 59
MPI IR ATI+DI+ MQNANLHNLPENYM+KYYMYHILSWPEASFVATTT D +D +Q
Sbjct: 1 MPINIRRATINDIICMQNANLHNLPENYMMKYYMYHILSWPEASFVATTTTLDCEDSDEQ 60
Query: 60 -------LTGEEEEDGKILSLPTETKLDPSYIAHTGEKLVGYVLAKMNDDPDSKETEPNG 112
LT + DG+ + KLDP+Y+A GEKLVGYVL KMNDDPD + PNG
Sbjct: 61 DENDKLELTLDGTNDGRTI------KLDPTYLA-PGEKLVGYVLVKMNDDPDQQNEPPNG 113
Query: 113 HITSLSVMRTYRRMGLAEKLMRQALFALCEVHKAKFVSLHVRQSNRAALHLYRDTLAFQV 172
HITSLSVMRTYRRMG+AE LMRQALFAL EVH+A++VSLHVRQSNRAALHLYRDTLAF+V
Sbjct: 114 HITSLSVMRTYRRMGIAENLMRQALFALREVHQAEYVSLHVRQSNRAALHLYRDTLAFEV 173
Query: 173 LSVESSYYQDGEDAYAMEKRLELEQLLPSSF------QNAQE-EDNLESDLFEDIVKQGV 225
LS+E SYYQDGEDAYAM+K L+LE+L S+F +N ++ ED+LESDL EDI+KQGV
Sbjct: 174 LSIEKSYYQDGEDAYAMKKVLKLEELQISNFTHRRLKENEEKLEDDLESDLLEDIIKQGV 233
Query: 226 EEISV 230
+I V
Sbjct: 234 NDIIV 238
>SPAC15E1.08 [R] KOG3235 Subunit of the major N alpha-acetyltransferase
Length = 177
Score = 179 bits (454), Expect = 3e-45
Identities = 97/187 (51%), Positives = 120/187 (63%), Gaps = 39/187 (20%)
Query: 5 IRHATIDDILAMQNANLHNLPENYMLKYYMYHILSWPEASFVATTTDDVDDIMDQLTGEE 64
IR A I D+ MQN NLHNLPENY LKYY+YH +SWP S+VAT
Sbjct: 3 IRPARISDLTGMQNCNLHNLPENYQLKYYLYHAISWPMLSYVAT---------------- 46
Query: 65 EEDGKILSLPTETKLDPSYIAHTGEKLVGYVLAKMNDDPDSKETEPNGHITSLSVMRTYR 124
DP ++VGYVLAKM ++P K+ P+GHITS+SVMR+YR
Sbjct: 47 ---------------DPK------GRVVGYVLAKMEEEP--KDGIPHGHITSVSVMRSYR 83
Query: 125 RMGLAEKLMRQALFALCEVHKAKFVSLHVRQSNRAALHLYRDTLAFQVLSVESSYYQDGE 184
+GLA++LM Q+ A+ EV+ AK++SLHVR+SNRAA+HLYRDTL F V +ES YY DGE
Sbjct: 84 HLGLAKRLMVQSQRAMVEVYGAKYMSLHVRKSNRAAIHLYRDTLQFDVQGIESKYYADGE 143
Query: 185 DAYAMEK 191
DAYAM K
Sbjct: 144 DAYAMHK 150
>Hs14249280 [R] KOG3235 Subunit of the major N alpha-acetyltransferase
Length = 229
Score = 170 bits (430), Expect = 2e-42
Identities = 95/191 (49%), Positives = 121/191 (62%), Gaps = 40/191 (20%)
Query: 3 ITIRHATIDDILAMQNANLHNLPENYMLKYYMYHILSWPEASFVATTTDDVDDIMDQLTG 62
+ IR+A DD++ MQ+ NL LPENY +KYY+YH LSWP+ S++A
Sbjct: 1 MNIRNAQPDDLMNMQHCNLLCLPENYQMKYYLYHGLSWPQLSYIA--------------- 45
Query: 63 EEEEDGKILSLPTETKLDPSYIAHTGEKLVGYVLAKMNDDPDSKETEPNGHITSLSVMRT 122
E+EDGKI VGYVLAKM ++PD P+GHITSL+V R+
Sbjct: 46 -EDEDGKI---------------------VGYVLAKMEEEPDD---VPHGHITSLAVKRS 80
Query: 123 YRRMGLAEKLMRQALFALCEVHKAKFVSLHVRQSNRAALHLYRDTLAFQVLSVESSYYQD 182
+RR+GLA+KLM QA A+ E AK+VSLHVR+SNR ALHLY +TL FQ+ VE YY D
Sbjct: 81 HRRLGLAQKLMDQASRAMIENFNAKYVSLHVRKSNRPALHLYSNTLNFQISEVEPKYYAD 140
Query: 183 GEDAYAMEKRL 193
GEDAYAM++ L
Sbjct: 141 GEDAYAMKRDL 151
>CE18023 [R] KOG3235 Subunit of the major N alpha-acetyltransferase
Length = 182
Score = 170 bits (430), Expect = 2e-42
Identities = 91/191 (47%), Positives = 118/191 (61%), Gaps = 40/191 (20%)
Query: 3 ITIRHATIDDILAMQNANLHNLPENYMLKYYMYHILSWPEASFVATTTDDVDDIMDQLTG 62
+ IR A +DD+++MQNANL LPENY +KYY YH LSWP+ S++A
Sbjct: 1 MNIRCARVDDLMSMQNANLMCLPENYQMKYYFYHALSWPQLSYIA--------------- 45
Query: 63 EEEEDGKILSLPTETKLDPSYIAHTGEKLVGYVLAKMNDDPDSKETEPNGHITSLSVMRT 122
E+ G + VGYVLAKM +DP EP+GHITSL+V R+
Sbjct: 46 -EDHKGNV---------------------VGYVLAKMEEDPGE---EPHGHITSLAVKRS 80
Query: 123 YRRMGLAEKLMRQALFALCEVHKAKFVSLHVRQSNRAALHLYRDTLAFQVLSVESSYYQD 182
YRR+GLA K+M Q A+ E + AK+VSLHVR SNRAAL+LY++TL F+++ E YY D
Sbjct: 81 YRRLGLANKMMDQTARAMVETYNAKYVSLHVRVSNRAALNLYKNTLKFEIVDTEPKYYAD 140
Query: 183 GEDAYAMEKRL 193
GEDAYAM + L
Sbjct: 141 GEDAYAMRRDL 151
>Hs10835057 [R] KOG3235 Subunit of the major N alpha-acetyltransferase
Length = 235
Score = 169 bits (428), Expect = 3e-42
Identities = 95/191 (49%), Positives = 121/191 (62%), Gaps = 40/191 (20%)
Query: 3 ITIRHATIDDILAMQNANLHNLPENYMLKYYMYHILSWPEASFVATTTDDVDDIMDQLTG 62
+ IR+A +D++ MQ+ NL LPENY +KYY YH LSWP+ S++A
Sbjct: 1 MNIRNARPEDLMNMQHCNLLCLPENYQMKYYFYHGLSWPQLSYIA--------------- 45
Query: 63 EEEEDGKILSLPTETKLDPSYIAHTGEKLVGYVLAKMNDDPDSKETEPNGHITSLSVMRT 122
E+E+GKI VGYVLAKM +DPD P+GHITSL+V R+
Sbjct: 46 -EDENGKI---------------------VGYVLAKMEEDPDD---VPHGHITSLAVKRS 80
Query: 123 YRRMGLAEKLMRQALFALCEVHKAKFVSLHVRQSNRAALHLYRDTLAFQVLSVESSYYQD 182
+RR+GLA+KLM QA A+ E AK+VSLHVR+SNRAALHLY +TL FQ+ VE YY D
Sbjct: 81 HRRLGLAQKLMDQASRAMIENFNAKYVSLHVRKSNRAALHLYSNTLNFQISEVEPKYYAD 140
Query: 183 GEDAYAMEKRL 193
GEDAYAM++ L
Sbjct: 141 GEDAYAMKRDL 151
>At5g13780 [R] KOG3235 Subunit of the major N alpha-acetyltransferase
Length = 192
Score = 162 bits (409), Expect = 5e-40
Identities = 90/195 (46%), Positives = 124/195 (63%), Gaps = 41/195 (21%)
Query: 3 ITIRHATIDDILAMQNANLHNLPENYMLKYYMYHILSWPEASFVATTTDDVDDIMDQLTG 62
+ IR AT+DD+LAMQ NL LPENY +KYY+YHILSWP+ +VA
Sbjct: 2 VCIRRATVDDLLAMQACNLMCLPENYQMKYYLYHILSWPQLLYVA--------------- 46
Query: 63 EEEEDGKILSLPTETKLDPSYIAHTGEKLVGYVLAKMNDDPDSKETEPNGHITSLSVMRT 122
E+ +G+I VGYVLAKM ++ + E +GHITSL+V+RT
Sbjct: 47 -EDYNGRI---------------------VGYVLAKMEEESN----ECHGHITSLAVLRT 80
Query: 123 YRRMGLAEKLMRQALFALCEVHKAKFVSLHVRQSNRAALHLYRDTLAFQVLSVESSYYQD 182
+R++GLA KLM A A+ +V++A++VSLHVR+SNRAA +LY +TL +++ VE+ YY D
Sbjct: 81 HRKLGLATKLMTAAQAAMEQVYEAEYVSLHVRRSNRAAFNLYTETLGYKINDVEAKYYAD 140
Query: 183 GEDAYAMEKRLELEQ 197
GEDAY M K L+ +Q
Sbjct: 141 GEDAYDMRKNLKGKQ 155
>7294847 [R] KOG3235 Subunit of the major N alpha-acetyltransferase
Length = 196
Score = 156 bits (395), Expect = 2e-38
Identities = 92/211 (43%), Positives = 125/211 (58%), Gaps = 41/211 (19%)
Query: 3 ITIRHATIDDILAMQNANLHNLPENYMLKYYMYHILSWPEASFVATTTDDVDDIMDQLTG 62
+ IR A +D++ MQ+ NL LPENY +KYY YH L+WP+ S+VA VDD
Sbjct: 1 MNIRCAKPEDLMTMQHCNLLCLPENYQMKYYFYHGLTWPQLSYVA-----VDD------- 48
Query: 63 EEEEDGKILSLPTETKLDPSYIAHTGEKLVGYVLAKMNDDPDSKETEPNGHITSLSVMRT 122
+VGYVLAKM ++P+ E +GHITSL+V R+
Sbjct: 49 -------------------------KGAIVGYVLAKM-EEPEPNEESRHGHITSLAVKRS 82
Query: 123 YRRMGLAEKLMRQALFALCEVHKAKFVSLHVRQSNRAALHLYRDTLAFQVLSVESSYYQD 182
YRR+GLA+KLM QA A+ E A++VSLHVR+SNRAAL+LY + L F+++ VE YY D
Sbjct: 83 YRRLGLAQKLMNQASQAMVECFNAQYVSLHVRKSNRAALNLYTNALKFKIIEVEPKYYAD 142
Query: 183 GEDAYAMEKRLEL---EQLLPSSFQNAQEED 210
GEDAYAM + L E ++ Q+ +EE+
Sbjct: 143 GEDAYAMRRDLSEFADEDQAKAAKQSGEEEE 173
>Hs7705823 [R] KOG3234 Acetyltransferase (GNAT) family
Length = 178
Score = 77.4 bits (189), Expect = 2e-14
Identities = 59/195 (30%), Positives = 85/195 (43%), Gaps = 46/195 (23%)
Query: 4 TIRHATIDDILAMQNANLHNLPENYMLKYYMYHILSWPEASFVATTTDDVDDIMDQLTGE 63
T+R T DD+ N NL L E Y + +Y+ ++ WPE VA
Sbjct: 3 TLRAFTCDDLFRFNNINLDPLTETYGIPFYLQYLAHWPEYFIVAEAP------------- 49
Query: 64 EEEDGKILSLPTETKLDPSYIAHTGEKLVGYVLAKMNDDPDSKETEPNGHITSLSVMRTY 123
G +L+GY++ K +E +GH+T+LSV +
Sbjct: 50 ------------------------GGELMGYIMGKAEGSVAREEW--HGHVTALSVAPEF 83
Query: 124 RRMGLAEKLMRQALFALCEVHKAKFVSLHVRQSNRAALHLYRDTLAFQVLSVESSYY--- 180
RR+GLA KLM + L + E FV L VR SN+ A+++Y+ L + V YY
Sbjct: 84 RRLGLAAKLM-ELLEEISERKGGFFVDLFVRVSNQVAVNMYKQ-LGYSVYRTVIEYYSAS 141
Query: 181 --QDGEDAYAMEKRL 193
+ EDAY M K L
Sbjct: 142 NGEPDEDAYDMRKAL 156
>7293615 [R] KOG3234 Acetyltransferase (GNAT) family
Length = 175
Score = 73.6 bits (179), Expect = 2e-13
Identities = 58/192 (30%), Positives = 85/192 (44%), Gaps = 45/192 (23%)
Query: 4 TIRHATIDDILAMQNANLHNLPENYMLKYYMYHILSWPEASFVATTTDDVDDIMDQLTGE 63
T+R T DD+ N N L E Y L +Y ++ WPE +A
Sbjct: 3 TLRPFTCDDLFKFNNVNFDPLTETYGLSFYTQYLAKWPEYFQLA---------------- 46
Query: 64 EEEDGKILSLPTETKLDPSYIAHTGEKLVGYVLAKMNDDPDSKETEPNGHITSLSVMRTY 123
E G+I+ GY++ K+ D+ +GH+T+L+V Y
Sbjct: 47 ESPSGQIM---------------------GYIMGKVEGHLDNW----HGHVTALTVSPDY 81
Query: 124 RRMGLAEKLMRQALFALCEVHKAKFVSLHVRQSNRAALHLYRDTLAFQVLSVESSYY--Q 181
RR+GLA LM L + E +A FV L VR+SN+ A+++Y + L + + YY
Sbjct: 82 RRLGLAALLM-SFLEDISEKKRAYFVDLFVRKSNQVAINMYTN-LGYIIYRTILEYYSGD 139
Query: 182 DGEDAYAMEKRL 193
EDAY M K L
Sbjct: 140 QDEDAYDMRKAL 151
>At1g03150 [R] KOG3234 Acetyltransferase (GNAT) family
Length = 174
Score = 70.5 bits (171), Expect = 2e-12
Identities = 56/214 (26%), Positives = 91/214 (42%), Gaps = 44/214 (20%)
Query: 4 TIRHATIDDILAMQNANLHNLPENYMLKYYMYHILSWPEASFVATTTDDVDDIMDQLTGE 63
TIR + +D+L + NL +L E + + +YM ++ WP+ VA
Sbjct: 3 TIRRFSCNDLLRFTSVNLDHLTETFNMSFYMTYLARWPDYFHVAEGP------------- 49
Query: 64 EEEDGKILSLPTETKLDPSYIAHTGEKLVGYVLAKMNDDPDSKETEPNGHITSLSVMRTY 123
G +++GY++ K+ +S +GH+T+++V Y
Sbjct: 50 ------------------------GNRVMGYIMGKVEGQGESW----HGHVTAVTVSPEY 81
Query: 124 RRMGLAEKLMRQALFALCEVHKAKFVSLHVRQSNRAALHLYRDTLAFQVLSVESSYYQDG 183
RR LA+KLM ++ KA FV L VR SN A+ +Y + L + + YY
Sbjct: 82 RRQQLAKKLMNLLEDISDKIDKAYFVDLFVRASNTPAIKMY-EKLGYIIYRRVLRYYSGE 140
Query: 184 EDAYAMEKRL--ELEQLLPSSFQNAQEEDNLESD 215
ED M K L ++E+ + D LE D
Sbjct: 141 EDGLDMRKALSRDVEKKSVIPLKRPITPDELEYD 174
>CE25639 [R] KOG3234 Acetyltransferase (GNAT) family
Length = 173
Score = 67.0 bits (162), Expect = 2e-11
Identities = 53/192 (27%), Positives = 86/192 (44%), Gaps = 45/192 (23%)
Query: 4 TIRHATIDDILAMQNANLHNLPENYMLKYYMYHILSWPEASFVATTTDDVDDIMDQLTGE 63
T+R + D+ N NL E Y ++Y+++++++PE VA
Sbjct: 3 TLRPFDVMDMFKFNNVNLDINTETYGFQFYLHYMMNYPEYYQVAE--------------- 47
Query: 64 EEEDGKILSLPTETKLDPSYIAHTGEKLVGYVLAKMNDDPDSKETEPNGHITSLSVMRTY 123
H +++ YV+ K+ + ++T +GH+T+LSV +
Sbjct: 48 ----------------------HPNGEIMAYVMGKI----EGRDTNWHGHVTALSVAPNF 81
Query: 124 RRMGLAEKLMRQALFALCEVHKAKFVSLHVRQSNRAALHLYRDTLAFQVLSVESSYY--Q 181
RR+GLA +M + L E +A FV L VR SN+ A+ LY+ L + V YY
Sbjct: 82 RRLGLAAYMM-EFLERTSEARRAYFVDLFVRVSNKIAIELYK-KLGYVVYRQIIGYYTGD 139
Query: 182 DGEDAYAMEKRL 193
EDA+ M K L
Sbjct: 140 RDEDAFDMRKSL 151
>YPR131c [R] KOG3234 Acetyltransferase (GNAT) family
Length = 251
Score = 66.6 bits (161), Expect = 3e-11
Identities = 49/178 (27%), Positives = 82/178 (45%), Gaps = 39/178 (21%)
Query: 12 DILAMQNANLHNLPENYMLKYYMYHILSWPEASFVATTTDDVDDIMDQLTGEEEEDGKIL 71
D+ N NL L EN+ L++Y +++ WP+ F +
Sbjct: 67 DLFKTNNVNLDILTENFPLEFYFEYMIIWPDLFFKS------------------------ 102
Query: 72 SLPTETKLDPSYIAHTGEKLVGYVLAKMNDDPDSKETEPNGHITSLSVMRTYRRMGLAEK 131
+E +DP++ + GY++AK + K TE + HIT+++V +RR+ LA K
Sbjct: 103 ---SEMTVDPTF----KHNISGYMMAK----TEGKTTEWHTHITAVTVAPRFRRISLASK 151
Query: 132 LMRQALFALCEV--HKAKFVSLHVRQSNRAALHLYRDTLAFQVLSVESSYYQDGEDAY 187
L L + +V H+ F+ L V+ +N+ A+ LY + L + V YY ED Y
Sbjct: 152 LC-NTLETMTDVMPHEVNFIDLFVKCNNQLAIKLY-EKLGYSVYRRVVGYYNSAEDGY 207
>At1g03650 [R] KOG3139 N-acetyltransferase
Length = 158
Score = 50.4 bits (119), Expect = 2e-06
Identities = 32/76 (42%), Positives = 42/76 (55%), Gaps = 2/76 (2%)
Query: 114 ITSLSVMRTYRRMGLAEKLMRQALFALCEVHKAKFVSLHVRQSNRAALHLYRDTLAFQVL 173
IT L+V RR G E L+R A+ C K + VSLHV + +A++LY+ L FQV
Sbjct: 77 ITKLAVKENCRRQGHGEALLRAAIDK-CRSRKVQRVSLHVDPTRTSAVNLYK-KLGFQVD 134
Query: 174 SVESSYYQDGEDAYAM 189
+ SYY DAY M
Sbjct: 135 CLVKSYYSADRDAYRM 150
>ECU06g0460 [R] KOG3235 Subunit of the major N alpha-acetyltransferase
Length = 181
Score = 50.1 bits (118), Expect = 3e-06
Identities = 49/194 (25%), Positives = 79/194 (40%), Gaps = 48/194 (24%)
Query: 3 ITIRHATIDDILAMQNANLHNLPENYMLKYYMYHILSWPEASFVATTTDDVDDIMDQLTG 62
+ R D+L +Q+ N+ N EN++L +F++T +
Sbjct: 24 VVFRGMRFKDLLEVQHLNIRNSTENFLL------------GTFLSTLS------------ 59
Query: 63 EEEEDGKILSLPTETKLDPSYIAHTGEKLVGYVLAKMNDDPDSKETEPNGHITSLSVMRT 122
T S++A G K+VGY A D G I S+ V
Sbjct: 60 --------------TSYGTSFVADLGGKIVGYSEAVAFAD------RGRGQIYSICVDGA 99
Query: 123 YRRMGLAEKLMR---QALFALCEVHKAKFVSLHVRQSNRAALHLYRDTLAFQVLSVESSY 179
+RR G+ +L+ +++ A E +A + LHVR SN A+ LY+ ++ F V Y
Sbjct: 100 FRRRGIGRRLINLSVESIRAELEGKEACEIDLHVRASNAEAIGLYK-SVGFVVCEANIPY 158
Query: 180 YQDGEDAYAMEKRL 193
Y+ G A+ M L
Sbjct: 159 YEFGGLAHRMSLTL 172
Database: KOG eukaryal database 04/03
Posted date: Apr 14, 2003 1:07 PM
Number of letters in database: 30,389,216
Number of sequences in database: 60,738
Lambda K H
0.315 0.132 0.366
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 13,786,997
Number of Sequences: 60738
Number of extensions: 587946
Number of successful extensions: 1994
Number of sequences better than 1.0e-05: 14
Number of HSP's better than 0.0 without gapping: 7
Number of HSP's successfully gapped in prelim test: 7
Number of HSP's that attempted gapping in prelim test: 1965
Number of HSP's gapped (non-prelim): 25
length of query: 230
length of database: 30,389,216
effective HSP length: 103
effective length of query: 127
effective length of database: 24,133,202
effective search space: 3064916654
effective search space used: 3064916654
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.6 bits)